OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Biotechnology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Wastewater-borne viruses and bacteria, surveillance and biosensors at the interface of academia and field deployment	198
Overview of resveratrol properties, applications, and advances in microbial precision fermentation	157
Bioreactor configurations for adventitious root culture: recent advances toward the commercial production of specialized metabolites	89
Design of novel enzymes with the incorporation of noncanonical amino acids	77
A comprehensive review on microbial urease: features and industrial applications	67
Smart reprograming of plants against salinity stress using modern biotechnological tools	59
Unveiling the potential of dendrobine: insights into bioproduction, bioactivities, safety, circular economy, and future prospects	57
Sustainable utilization of fruit and vegetable waste bioresources for bioplastics production	51
Recent updates on green synthesis of lignin nanoparticle and its potential applications in modern biotechnology	47
Advances in the development of phage-mediated cyanobacterial cell lysis	45
Electrospun wound dressings with antibacterial function: a critical review of plant extract and essential oil incorporation	44
Functional genomics in sugarcane breeding: key challenges and strategies	44
Enzyme hybrid nanoflowers and enzyme@metal–organic frameworks composites: fascinating hybrid nanobiocatalysts	43
An update on experimental to large-scale production of bacteriophages against superbugs: a review	42
Cold-active enzymes from deep marine psychrophiles: harnessing their potential in enhanced food production and sustainability	40
Advances in the metabolic engineering of Saccharomyces cerevisiae and Yarrowia lipolytica for the production of β	40
3D printing: trends and approaches toward achieving long-term sustainability in the food industry	40
Advances in high-throughput screening approaches for biosurfactants: current trends, bottlenecks and perspectives	39
Biomaterials for eco-friendly packaging in dairy products: towards a cleaner, greener, and sustainable future	38
Enhancing plastic biodegradation process: strategies and opportunities	37
Antimicrobials from endophytes as novel therapeutics to counter drug-resistant pathogens	37
Synthetic biology for the food industry: advances and challenges	36
Bacterial genome reduction for optimal chassis of synthetic biology: a review	36
Biofilm formation in xenobiotic-degrading microorganisms	35
Whole recombinant yeast-based vaccines: concept, importance, issues, and future scope	35

Diversity of fungus-mediated synthesis of gold nanoparticles: properties, mechanisms, challenges, and solving methods	35
Harnessing microbial division of labor for biomanufacturing: a review of laboratory and formal modeling approaches	33
Current trends in solid tannery waste management	33
A close-up of regulatory networks and signaling pathways of MKK5 in biotic and abiotic stresses	32
Structural diversity, biosynthesis, and extraction of brown algae fucoidan and its bio-stimulant applications in crop improvement	31
Calcium-dependent protein kinase (CDPK/CPK)-mediated salicylic acid cascade: the key arsenal of plants under pathogens attack	30
Unveiling the silent defenders: mycobacterial stress sensors at the forefront to combat tuberculosis	30
A crosswalk on the genetic and conventional strategies for enhancing astaxanthin production in Haematococcus pluvialis	30
Sustainable and biotechnological production of docosahexaenoic acid from marine protists and slaughterhouse waste	29
Field and laboratory guidelines for reliable bioinformatic and statistical analysis of bacterial shotgun metagenomic data	29
Crucial aspects of metabolism and cell biology relating to industrial production and processing of Saccharomyces biomass	28
Critical analysis of analytical techniques developed for statins in biological fluids, environmental and fermentation samples	28
Systems seed biology to understand and manipulate rice grain quality and nutrition	28
Microalgae-based strategies for cadmium remediation: insights, challenges, and future directions	27
Microbial lipids for a sustainable future: the growing potential of synthetic microbial engineering for consumer oils	27
The thermal cycling methods for rapid PCR	26
A story of two kingdoms: unravelling the intricacies of protein phase separation in plants and animals	26
Synergetic anaerobic digestion of food waste for enhanced production of biogas and value-added products: strategies, challenges, and techno-economic analysis	25
A comprehensive review on tissue culture studies and secondary metabolite production in Bacopa monnieri L. Pennell: a nootropic plant	25
Available strategies for improving the biosynthesis of surfactin: a review	25
Molecular modification and biotechnological applications of microbial aspartic proteases	25
Nanobiosensors and their role in detection of adulterants and contaminants in food products	24
Catalytic mechanisms underlying fungal fatty acid desaturases activities	24
Research progress on the application of cell-free synthesis systems for enzymatic processes	23
Thraustochytrids as a promising source of fatty acids, carotenoids, and sterols: bioactive compound biosynthesis, and modern biotechnology	22
D-allulose 3-epimerase for low-calorie D-allulose synthesis: microbial production, characterization, and applications	22
New strategies to study in depth the metabolic mechanism of astaxanthin biosynthesis in Phaffia rhodozyma	22
Bio-based vitamin B12: bridging biotechnology and sustainability for industrial production	22
Recent advances in hierarchically porous metal-organic frameworks mediated enzyme immobilization: progress and perspective	22
Amplification-free nucleic acids detection with next-generation CRISPR/dx systems	22
Microbial cell factories using Paenibacillus : status and perspectives	22
Value-added biotransformation of agricultural byproducts by cellulolytic fungi: a review	21
Strategies to improve the efficiency and quality of mutant breeding using heavy-ion beam irradiation	21
Fashion meets science: how advanced breeding approaches could revolutionize the textile industry	21
The mini revolution: application of mini-bioreactors in adaptive laboratory evolution	21
Extension characteristics of TdT and its application in biosensors	20
Brassinosteroid-modified crops: key players for a modern Green Revolution	20
Microbial production of vitamin B5: current status and prospects	20
Microbial alchemy: upcycling of brewery spent grains into high-value products through fermentation	20
Metabolic engineering of Saccharomyces cerevisiae for the synthesis of valuable chemicals	19
Bioactive compounds from Cordyceps and their therapeutic potential	19
Cyanobacterial myxoxanthophylls: biotechnological interventions and biological implications	19
How do probiotics alleviate constipation? A narrative review of mechanisms	19
Advancing transcriptional regulation in Yarrowia lipolytica : from endogenous promoter discovery to synthetic promoter engineering	19
APETALA2/ethylene-responsive factors in higher plant and their roles in regulation of plant stress response	19
Harnessing the advances of genetic engineering in microalgae for the production of cannabinoids	18
Challenges and progress toward real-time detection of airborne viral pathogens	17
Emerging green cell disruption techniques to obtain valuable compounds from macro and microalgae: a review	17
Engineering industrial yeast for improved tolerance and robustness	17
Chinese cordyceps products, geographic traceability and authenticity assessment: current status, challenges, and future directions	17

Emerging alternative food protein sources: production process, quality parameters, and safety point of view	17
Bacteriophages: a potential game changer in food processing industry	16
Microbial granules on reactors performance during organic butyrate digestion: clean production	16
A comprehensive review on the recent advances for 5-aminolevulinic acid production by the engineered bacteria	16
Upcoming generation nanoengineered antimicrobial delivery system for targeting multidrug-resistant microbes	16
Glycosylation of cellulase: a novel strategy for improving cellulase	16
Iridoid glycosides from Picrorhiza genus endemic to the Himalayan region: phytochemistry, biosynthesis, pharmacological potential and biotechnological intercessions to b	16
Current trends and possibilities of typical microbial protein production approaches: a review	16
Algae: the game-changers in biohydrogen sector	15
Potato microtuberization: its regulation and applications	15
Insight into recent advances in microalgae biogranulation in wastewater treatment	15
Developed and emerging 1,4-butanediol commercial production strategies: forecasting the current status and future possibility	15
Sustainable management of tea wastes: resource recovery and conversion techniques	15
Fungal pellets as biotechnological tools for addressing environmental and industrial challenges: a comprehensive review	15
Ultrasonic processing: effects on the physicochemical and microbiological aspects of dairy products	15
Antiviral and antibacterial properties of phloroglucinols: a review on naturally occurring and (semi)synthetic derivatives with potential therapeutic interest	14
Oligonucleotide probes for imaging and diagnosis of bacterial infections	14
Strategies for modulating transglycosylation activity, substrate specificity, and product polymerization degree of engineered transglycosylases	14
Modern approaches to engineering human reporter cell lines using CRISPR within Safe Harbor loci and endogenous genes	14
Rhodococcus: sequences of genetic parts, analysis of their functionality, and development prospects as a molecular biology platform	14
Regulation of fatty acid synthesis in oilseed crops: multidimensional insights and strategies for enhancing oil quality	14
The development of active membranes: use of immobilized enzymes as fouling-reducing and self-cleaning agents	14
Pilot scale polyhydroxyalkanoates biopolymer production using pure cultures: current status and future opportunities	14
Microbial bioprocess performance in nanoparticle-mediated composting	13
Engineering traits through CRISPR/cas genome editing in woody species to improve forest diversity and yield	13
Transcriptional control in microalgae: co-regulated fatty acid biosynthesis and carbon dioxide fixation	13
Microbial assisted multifaceted amelioration processes of heavy-metal remediation: a clean perspective toward sustainable and greener future	13
Advances in AI-based strategies and tools to facilitate natural product and drug development	13
Biological production of nicotinamide mononucleotide: a review	12
Astaxanthin biosynthesis for functional food development and space missions	12
Synthesis of C–N bonds by nicotinamide-dependent oxidoreductase: an overview	12
Advanced diagnostic methods for identification of bacterial foodborne pathogens: contemporary and upcoming challenges	12
Recent advances and prospects of Bacillus amyloliquefaciens as microbial cell factories: from rational design to industrial applications	12
Every road leads to Rome: diverse biosynthetic regulation of plant cell wall-degrading enzymes in filamentous fungi Penicillium oxalicum and Trichoderma r	12
Fungi in global hydrocarbon bioremediation: biodiversity, enzymatic pathways and technological innovations	12
Chitin and chitosan from shellfish waste and their applications in agriculture and biotechnology industries	12
An overview on fermentation strategies to overcome lignocellulosic inhibitors in second-generation ethanol production using cell immobilization	12
Biodegradable acids for pyrite depression and green flotation separation – an overview	11
Cold stress regulates accumulation of flavonoids and terpenoids in plants by phytohormone, transcription process, functional enzyme, and epigenetics	11
Advances in pharmacology, biosynthesis, and metabolic engineering of Scutellaria -specialized metabolites	11
Graphene as a nano-delivery vehicle in agriculture – current knowledge and future prospects	11
Pulmonary delivery systems for antimicrobial peptides	11
Cambial meristematic cell culture: a sustainable technology toward in vitro specialized metabolites production	11
Application of protein engineering to ene-reductase for the synthesis of chiral compounds through asymmetric reaction	10
Utilization of arbuscular mycorrhizal fungi symbiosis-related genes from host plants in biotechnology for sustainable agriculture	10
Biocontrol of plant pathogens in omics era—with special focus on endophytic bacilli	10
Biotechnological application of Aureobasidium spp. as a promising chassis for biosynthesis of ornithine-urea cycle-derived bioproducts	10
Mitigating toxic formaldehyde to promote efficient utilization of C1 resources	10
Deciphering the mechanism of microalgal metabolite-protein interaction for polyhydroxyalkanoates production	10
Chassis engineering for high light tolerance in microalgae and cyanobacteria	10
Spotlight on pectinase: a comprehensive review of large-scale production strategies	10
Air biofilters for a mixture of organic gaseous pollutants: an approach for industrial applications	10
Exploring future applications of the apiculate yeast Hanseniaspora	10
Xylooligosaccharides mediated gut microbiome modulation: prebiotics to postbiotics	10