Critical Reviews in Biotechnology

Article	Citations
Elucidation of transfer RNAs as stress regulating agents and the experimental strategies to conceive the functional role of tRNA-derived fragments in plants	135
Overview of resveratrol properties, applications, and advances in microbial precision fermentation	127
Unveiling the potential of dendrobine: insights into bioproduction, bioactivities, safety, circular economy, and future prospects	87
Recent updates on green synthesis of lignin nanoparticle and its potential applications in modern biotechnology	85
Advances in the development of phage-mediated cyanobacterial cell lysis	76
Sustainability of biodegradable plastics: a review on social, economic, and environmental factors	76
Plant lipid phosphate phosphatases: current advances and future outlooks	62
Wastewater-borne viruses and bacteria, surveillance and biosensors at the interface of academia and field deployment	60
Sustainable utilization of fruit and vegetable waste bioresources for bioplastics production	59
Yarrowia lipolytica as a biorefinery platform for effluents and solid wastes valorization – challenges and opportunities	57
Electrospun wound dressings with antibacterial function: a critical review of plant extract and essential oil incorporation	56
Bioreactor configurations for adventitious root culture: recent advances toward the commercial production of specialized metabolites	54
Enzyme hybrid nanoflowers and enzyme@metal–organic frameworks composites: fascinating hybrid nanobiocatalysts	52
Smart reprograming of plants against salinity stress using modern biotechnological tools	51
Potential use of gene drive modified insects against disease vectors, agricultural pests and invasive species poses new challenges for risk assessment	50
Advances in production of high-value lipids by oleaginous yeasts	47
Advances in the metabolic engineering of Saccharomyces cerevisiae and Yarrowia lipolytica for the production of β	45
Biological and biorational management of blast diseases in cereals caused by Magnaporthe oryzae	44
Neurodegenerative disorders management: state-of-art and prospects of nano-biotechnology	43
Fermentation strategies to improve propionic acid production withpropionibacteriumssp.: a review	43
Advances in high-throughput screening approaches for biosurfactants: current trends, bottlenecks and perspectives	41
Synthetic biology for the food industry: advances and challenges	40
Recent development of phenyllactic acid: physicochemical properties, biotechnological production strategies and applications	40
Biomaterials for eco-friendly packaging in dairy products: towards a cleaner, greener, and sustainable future	39
3D printing: trends and approaches toward achieving long-term sustainability in the food industry	39

Diversity of fungus-mediated synthesis of gold nanoparticles: properties, mechanisms, challenges, and solving methods	39
Role of proteins in the biosynthesis and functioning of metallic nanoparticles	38
Bacterial genome reduction for optimal chassis of synthetic biology: a review	38
Enhancing plastic biodegradation process: strategies and opportunities	37
Production and waste treatment of polyesters: application of bioresources and biotechniques	37
Antimicrobials from endophytes as novel therapeutics to counter drug-resistant pathogens	36
Biofilm formation in xenobiotic-degrading microorganisms	36
A close-up of regulatory networks and signaling pathways of MKK5 in biotic and abiotic stresses	35
Perfusion culture of Chinese Hamster Ovary cells for bioprocessing applications	35
Harnessing microbial division of labor for biomanufacturing: a review of laboratory and formal modeling approaches	35
Cold-active enzymes from deep marine psychrophiles: harnessing their potential in enhanced food production and sustainability	35
A crosswalk on the genetic and conventional strategies for enhancing astaxanthin production in Haematococcus pluvialis	34
Current trends in solid tannery waste management	34
Proteomics for abiotic stresses in legumes: present status and future directions	33
Unveiling the silent defenders: mycobacterial stress sensors at the forefront to combat tuberculosis	32
Marine algal flavonoids and phlorotannins; an intriguing frontier of biofunctional secondary metabolites	32
Improving environmental stress resilience in crops by genome editing: insights from extremophile plants	31
Pluripotent stem cells for skeletal tissue engineering	31
Advances in sustainable approaches utilizing orange peel waste to produce highly value-added bioproducts	31
Field and laboratory guidelines for reliable bioinformatic and statistical analysis of bacterial shotgun metagenomic data	31
Critical analysis of analytical techniques developed for statins in biological fluids, environmental and fermentation samples	30
Crucial aspects of metabolism and cell biology relating to industrial production and processing of Saccharomyces biomass	30
Available strategies for improving the biosynthesis of surfactin: a review	30
A story of two kingdoms: unravelling the intricacies of protein phase separation in plants and animals	29
Systems seed biology to understand and manipulate rice grain quality and nutrition	29
Synergetic anaerobic digestion of food waste for enhanced production of biogas and value-added products: strategies, challenges, and techno-economic analysis	28
Amylases from thermophilic bacteria: structure and function relationship	28
Microbial cell factories using Paenibacillus : status and perspectives	28
Recent trends in nanomaterial-based signal amplification in electrochemical aptasensors	28
New strategies to study in depth the metabolic mechanism of astaxanthin biosynthesis in Phaffia rhodozyma	27
Molecular modification and biotechnological applications of microbial aspartic proteases	27
Insights into organic loading rates of anaerobic digestion for biogas production: a review	25
Amplification-free nucleic acids detection with next-generation CRISPR/dx systems	25
D-allulose 3-epimerase for low-calorie D-allulose synthesis: microbial production, characterization, and applications	25
Membrane bioreactors for syngas permeation and fermentation	24
Nanobiosensors and their role in detection of adulterants and contaminants in food products	24
Co-culturing microbial consortia: approaches for applications in biomanufacturing and bioprocessing	24
Strategies to improve the efficiency and quality of mutant breeding using heavy-ion beam irradiation	24
Research progress on the application of cell-free synthesis systems for enzymatic processes	24
Catalytic mechanisms underlying fungal fatty acid desaturases activities	24
Optimum chalcone synthase for flavonoid biosynthesis in microorganisms	24
A comprehensive review on tissue culture studies and secondary metabolite production in Bacopa monnieri L. Pennell: a nootropic plant	24
Thraustochytrids as a promising source of fatty acids, carotenoids, and sterols: bioactive compound biosynthesis, and modern biotechnology	23
Fashion meets science: how advanced breeding approaches could revolutionize the textile industry	23
Emerging trends in high-solids enzymatic saccharification of lignocellulosic feedstocks for developing an efficient and industrially deployable sugar platform	23
How do probiotics alleviate constipation? A narrative review of mechanisms	23
A review on biomass-derived levulinic acid for application in drug synthesis	23
Value-added biotransformation of agricultural byproducts by cellulolytic fungi: a review	23
Microbial production of vitamin B5: current status and prospects	22
Microbial alchemy: upcycling of brewery spent grains into high-value products through fermentation	22

Extension characteristics of TdT and its application in biosensors	22
APETALA2/ethylene-responsive factors in higher plant and their roles in regulation of plant stress response	20
Efficient heterologous expression of cytochrome P450 enzymes in microorganisms for the biosynthesis of natural products	20
Engineering industrial yeast for improved tolerance and robustness	20
Harnessing the advances of genetic engineering in microalgae for the production of cannabinoids	19
Cyanobacterial myxoxanthophylls: biotechnological interventions and biological implications	19
Production, properties, and applications of fructosyltransferase: a current appraisal	18
Bioactive compounds from Cordyceps and their therapeutic potential	18
Emerging green cell disruption techniques to obtain valuable compounds from macro and microalgae: a review	18
Emerging alternative food protein sources: production process, quality parameters, and safety point of view	17
Glycosylation of cellulase: a novel strategy for improving cellulase	17
Metabolic engineering of Saccharomyces cerevisiae for the synthesis of valuable chemicals	17
Progress of metabolic engineering for the production of eicosapentaenoic acid	17
Deciphering the role of miRNA in reprogramming plant responses to drought stress	16
Current trends and possibilities of typical microbial protein production approaches: a review	16
A comprehensive review on the recent advances for 5-aminolevulinic acid production by the engineered bacteria	16
Bioproduction of l- and d-lactic acids: advances and trends in microbial strain application and engineering	16
Delineating the epigenetic regulation of heat and drought response in plants	16
Molecular prospective on the wheat grain development	16
Microbial granules on reactors performance during organic butyrate digestion: clean production	16
Au-courant and novel technologies for efficient doubled haploid development in barley (Hordeum vulgare L.)	16
Developed and emerging 1,4-butanediol commercial production strategies: forecasting the current status and future possibility	15
Sustainable management of tea wastes: resource recovery and conversion techniques	15
Pilot scale polyhydroxyalkanoates biopolymer production using pure cultures: current status and future opportunities	15
Insights in detection and analysis of organophosphates using organophosphorus acid anhydrolases (OPAA) enzyme-based biosensors	15
Bacteriophages: a potential game changer in food processing industry	15
Insight into recent advances in microalgae biogranulation in wastewater treatment	15
Iridoid glycosides from Picrorhiza genus endemic to the Himalayan region: phytochemistry, biosynthesis, pharmacological potential and biotechnological intercessions to b	15
Advances in biological production of acetoin: a comprehensive overview	14
Antiviral and antibacterial properties of phloroglucinols: a review on naturally occurring and (semi)synthetic derivatives with potential therapeutic interest	14
Microbial torularhodin – a comprehensive review	14
Rhodococcus: sequences of genetic parts, analysis of their functionality, and development prospects as a molecular biology platform	14
Potential use of fungal-bacterial co-cultures for the removal of organic pollutants	14
Algae: the game-changers in biohydrogen sector	14
Strategies for modulating transglycosylation activity, substrate specificity, and product polymerization degree of engineered transglycosylases	14
Microbial bioprocess performance in nanoparticle-mediated composting	14
Ultrasonic processing: effects on the physicochemical and microbiological aspects of dairy products	14
Bioelimination of low methane concentrations emitted from wastewater treatment plants: a review	13
Advances in AI-based strategies and tools to facilitate natural product and drug development	13
Engineering traits through CRISPR/cas genome editing in woody species to improve forest diversity and yield	13
Chitin and chitosan from shellfish waste and their applications in agriculture and biotechnology industries	13
Oligonucleotide probes for imaging and diagnosis of bacterial infections	13
The challenges of using NAD+-dependent formate dehydrogenases for CO2conversion	13
Microbial assisted multifaceted amelioration processes of heavy-metal remediation: a clean perspective toward sustainable and greener future	13
Advanced diagnostic methods for identification of bacterial foodborne pathogens: contemporary and upcoming challenges	12
Metabolic engineering strategies for sesquiterpene production in microorganism	12
Intracellular biosensor-based dynamic regulation to manipulate gene expression at the spatiotemporal level	12
Biological production of nicotinamide mononucleotide: a review	12
Recent advances and prospects of Bacillus amyloliquefaciens as microbial cell factories: from rational design to industrial applications	12
Enzyme producing insect gut microbes: an unexplored biotechnological aspect	11
Current evidence in high throughput ultrafiltration toward the purification of monoclonal antibodies (mAbs) and biotechnological protein-type molecules	11
Every road leads to Rome: diverse biosynthetic regulation of plant cell wall-degrading enzymes in filamentous fungi Penicillium oxalicum and Trichoderma r	11
Strategies for tailoring pH performances of glycoside hydrolases	11
Astaxanthin biosynthesis for functional food development and space missions	11
Rediscovering bacterial exopolysaccharides of terrestrial and marine origins: novel insights on their distribution, biosynthesis, biotechnological production, and future perspectives	11
Phospholipids (PLs) know-how: exploring and exploiting phospholipase D for its industrial dissemination	11
Immobilized enzyme for screening and identification of anti-diabetic components from natural products by ligand fishing	11
Response mechanisms to acid stress of acid-resistant bacteria and biotechnological applications in the food industry	11
An overview on fermentation strategies to overcome lignocellulosic inhibitors in second-generation ethanol production using cell immobilization	10
Plant response to silver nanoparticles: a critical review	10
Enzymes and pathways in microbial production of 2,3-butanediol and 3-acetoin isomers	10
Graphene as a nano-delivery vehicle in agriculture – current knowledge and future prospects	10
Cold stress regulates accumulation of flavonoids and terpenoids in plants by phytohormone, transcription process, functional enzyme, and epigenetics	10
Synthesis of C–N bonds by nicotinamide-dependent oxidoreductase: an overview	10
Cambial meristematic cell culture: a sustainable technology toward in vitro specialized metabolites production	10
High-throughput genetic engineering tools for regulating gene expression in a microbial cell factory	10
Use of elicitors to enhance or activate the antibiotic production in streptomyces	10
Application of protein engineering to ene-reductase for the synthesis of chiral compounds through asymmetric reaction	9
Biodegradable acids for pyrite depression and green flotation separation – an overview	9
Challenges and opportunities for the production of lactic acid bacteria inoculants aimed for ensiling processes	9
Air biofilters for a mixture of organic gaseous pollutants: an approach for industrial applications	9
Pulmonary delivery systems for antimicrobial peptides	9
Microalgae harvesting techniques: updates and recent technological interventions	9
Bioactive components from Moringa oleifera seeds: production, functionalities and applications – a critical review	9
Liamocins biosynthesis, its regulation in Aureobasidium spp., and their bioactivities	9
Mitigating toxic formaldehyde to promote efficient utilization of C1 resources	9
Advances in pharmacology, biosynthesis, and metabolic engineering of Scutellaria -specialized metabolites	9
Chassis engineering for high light tolerance in microalgae and cyanobacteria	9
Exploring future applications of the apiculate yeast Hanseniaspora	8
Fast-growing cyanobacterial chassis for synthetic biology application	8

Xylooligosaccharides mediated gut microbiome modulation: prebiotics to postbiotics	8
A strategy of co-fermentation of distillers dried grains with solubles (DDGS) and lignocellulosic feedstocks as swine feed	8
Biosynthesis, acquisition, regulation, and upcycling of heme: recent advances	8
Biotechnological application of Aureobasidium spp. as a promising chassis for biosynthesis of ornithine-urea cycle-derived bioproducts	8
Recent advancements in CRISPR-Cas toolbox for imaging applications	8
Advancements in multi-omics for nutraceutical enhancement and traits improvement in buckwheat	8