OOIR: Observatory of International Research

Papers

(The median citation count of Critical Reviews in Biotechnology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Wastewater-borne viruses and bacteria, surveillance and biosensors at the interface of academia and field deployment	204
Advances in the development of phage-mediated cyanobacterial cell lysis	99
Functional genomics in sugarcane breeding: key challenges and strategies	81
Unveiling the potential of dendrobine: insights into bioproduction, bioactivities, safety, circular economy, and future prospects	73
Overview of resveratrol properties, applications, and advances in microbial precision fermentation	64
Sustainable utilization of fruit and vegetable waste bioresources for bioplastics production	52
A comprehensive review on microbial urease: features and industrial applications	51
Bioreactor configurations for adventitious root culture: recent advances toward the commercial production of specialized metabolites	50
Recent updates on green synthesis of lignin nanoparticle and its potential applications in modern biotechnology	48
Electrospun wound dressings with antibacterial function: a critical review of plant extract and essential oil incorporation	47
Design of novel enzymes with the incorporation of noncanonical amino acids	46
Smart reprograming of plants against salinity stress using modern biotechnological tools	46
Enzyme hybrid nanoflowers and enzyme@metal–organic frameworks composites: fascinating hybrid nanobiocatalysts	46
Advances in the metabolic engineering of Saccharomyces cerevisiae and Yarrowia lipolytica for the production of β	45
An update on experimental to large-scale production of bacteriophages against superbugs: a review	45
Bacterial genome reduction for optimal chassis of synthetic biology: a review	44
Diversity of fungus-mediated synthesis of gold nanoparticles: properties, mechanisms, challenges, and solving methods	43
Cold-active enzymes from deep marine psychrophiles: harnessing their potential in enhanced food production and sustainability	41
Synthetic biology for the food industry: advances and challenges	39
Biomaterials for eco-friendly packaging in dairy products: towards a cleaner, greener, and sustainable future	39
Enhancing plastic biodegradation process: strategies and opportunities	39
Advances in high-throughput screening approaches for biosurfactants: current trends, bottlenecks and perspectives	39
Biofilm formation in xenobiotic-degrading microorganisms	37
Antimicrobials from endophytes as novel therapeutics to counter drug-resistant pathogens	36
3D printing: trends and approaches toward achieving long-term sustainability in the food industry	34

Whole recombinant yeast-based vaccines: concept, importance, issues, and future scope	33
A close-up of regulatory networks and signaling pathways of MKK5 in biotic and abiotic stresses	32
A crosswalk on the genetic and conventional strategies for enhancing astaxanthin production in Haematococcus pluvialis	32
Electrochemical biosensor for breast cancer biomarker detection based on advanced carbon materials: recent progress and future prospects	32
Structural diversity, biosynthesis, and extraction of brown algae fucoidan and its bio-stimulant applications in crop improvement	32
Calcium-dependent protein kinase (CDPK/CPK)-mediated salicylic acid cascade: the key arsenal of plants under pathogens attack	32
Field and laboratory guidelines for reliable bioinformatic and statistical analysis of bacterial shotgun metagenomic data	31
Harnessing microbial division of labor for biomanufacturing: a review of laboratory and formal modeling approaches	31
Microbial lipids for a sustainable future: the growing potential of synthetic microbial engineering for consumer oils	30
Sustainable and biotechnological production of docosahexaenoic acid from marine protists and slaughterhouse waste	30
Unveiling the silent defenders: mycobacterial stress sensors at the forefront to combat tuberculosis	30
Critical analysis of analytical techniques developed for statins in biological fluids, environmental and fermentation samples	29
Microalgae-based strategies for cadmium remediation: insights, challenges, and future directions	29
A story of two kingdoms: unravelling the intricacies of protein phase separation in plants and animals	28
The thermal cycling methods for rapid PCR	28
Available strategies for improving the biosynthesis of surfactin: a review	27
Synergetic anaerobic digestion of food waste for enhanced production of biogas and value-added products: strategies, challenges, and techno-economic analysis	26
Sustainable production strategies of omega-3 PUFAs and their enrichment in the human diet	25
New strategies to study in depth the metabolic mechanism of astaxanthin biosynthesis in Phaffia rhodozyma	25
Research progress on the application of cell-free synthesis systems for enzymatic processes	24
Recent advances in hierarchically porous metal-organic frameworks mediated enzyme immobilization: progress and perspective	24
Nanobiosensors and their role in detection of adulterants and contaminants in food products	24
Microbial cell factories using Paenibacillus : status and perspectives	24
D-allulose 3-epimerase for low-calorie D-allulose synthesis: microbial production, characterization, and applications	24
Therapeutic recombinant L-asparaginases: a comprehensive review and way forward	23
The mini revolution: application of mini-bioreactors in adaptive laboratory evolution	23
Molecular modification and biotechnological applications of microbial aspartic proteases	23
Value-added biotransformation of agricultural byproducts by cellulolytic fungi: a review	23
Fashion meets science: how advanced breeding approaches could revolutionize the textile industry	23
Strategies to improve the efficiency and quality of mutant breeding using heavy-ion beam irradiation	23
Thraustochytrids as a promising source of fatty acids, carotenoids, and sterols: bioactive compound biosynthesis, and modern biotechnology	23
Amplification-free nucleic acids detection with next-generation CRISPR/dx systems	23
Extension characteristics of TdT and its application in biosensors	22
APETALA2/ethylene-responsive factors in higher plant and their roles in regulation of plant stress response	22
Bio-based vitamin B12: bridging biotechnology and sustainability for industrial production	22
Brassinosteroid-modified crops: key players for a modern Green Revolution	22
Microbial production of vitamin B5: current status and prospects	22
Metabolic engineering of Saccharomyces cerevisiae for the synthesis of valuable chemicals	21
Microbial alchemy: upcycling of brewery spent grains into high-value products through fermentation	21
How do probiotics alleviate constipation? A narrative review of mechanisms	21
Advancing transcriptional regulation in Yarrowia lipolytica : from endogenous promoter discovery to synthetic promoter engineering	20
Engineering industrial yeast for improved tolerance and robustness	19
Chinese cordyceps products, geographic traceability and authenticity assessment: current status, challenges, and future directions	19
Bioactive compounds from Cordyceps and their therapeutic potential	19
Emerging alternative food protein sources: production process, quality parameters, and safety point of view	19
Cyanobacterial myxoxanthophylls: biotechnological interventions and biological implications	19
Upcoming generation nanoengineered antimicrobial delivery system for targeting multidrug-resistant microbes	18
Glycosylation of cellulase: a novel strategy for improving cellulase	18
Microbial granules on reactors performance during organic butyrate digestion: clean production	18
Challenges and progress toward real-time detection of airborne viral pathogens	18

Bacteriophages: a potential game changer in food processing industry	17
Fungal pellets as biotechnological tools for addressing environmental and industrial challenges: a comprehensive review	17
From discovery to application: cytochrome P450 enzyme in filamentous fungi for biosynthesis of steroids	17
Current trends and possibilities of typical microbial protein production approaches: a review	17
Sustainable management of tea wastes: resource recovery and conversion techniques	17
A comprehensive review on the recent advances for 5-aminolevulinic acid production by the engineered bacteria	17
Iridoid glycosides from Picrorhiza genus endemic to the Himalayan region: phytochemistry, biosynthesis, pharmacological potential and biotechnological in	17
Strategies for modulating transglycosylation activity, substrate specificity, and product polymerization degree of engineered transglycosylases	17
Potato microtuberization: its regulation and applications	16
Pilot scale polyhydroxyalkanoates biopolymer production using pure cultures: current status and future opportunities	16
Microbial engineering for the conversion of C1 feedstocks into value-added bioproducts: recent advances and perspectives	16
Developed and emerging 1,4-butanediol commercial production strategies: forecasting the current status and future possibility	16
Advances, challenges, and opportunities in engineering C5 and C6 sugar transporters in yeast for bio-based industrial biotechnology	16
Algae: the game-changers in biohydrogen sector	16
Modern approaches to engineering human reporter cell lines using CRISPR within Safe Harbor loci and endogenous genes	15
Ultrasonic processing: effects on the physicochemical and microbiological aspects of dairy products	15
Antiviral and antibacterial properties of phloroglucinols: a review on naturally occurring and (semi)synthetic derivatives with potential therapeutic interest	15
Insight into recent advances in microalgae biogranulation in wastewater treatment	15
The development of active membranes: use of immobilized enzymes as fouling-reducing and self-cleaning agents	14
Oligonucleotide probes for imaging and diagnosis of bacterial infections	14
Regulation of fatty acid synthesis in oilseed crops: multidimensional insights and strategies for enhancing oil quality	14
Microbial bioprocess performance in nanoparticle-mediated composting	13
Chitin and chitosan from shellfish waste and their applications in agriculture and biotechnology industries	13
Advances in AI-based strategies and tools to facilitate natural product and drug development	13
Microbial assisted multifaceted amelioration processes of heavy-metal remediation: a clean perspective toward sustainable and greener future	13
Engineering traits through CRISPR/cas genome editing in woody species to improve forest diversity and yield	13
Transcriptional control in microalgae: co-regulated fatty acid biosynthesis and carbon dioxide fixation	13
Astaxanthin biosynthesis for functional food development and space missions	12
Development strategies for engineered live biotherapeutic products for metabolic diseases	12
Synthesis of C–N bonds by nicotinamide-dependent oxidoreductase: an overview	12
Biological production of nicotinamide mononucleotide: a review	12
Fungi in global hydrocarbon bioremediation: biodiversity, enzymatic pathways and technological innovations	12
Every road leads to Rome: diverse biosynthetic regulation of plant cell wall-degrading enzymes in filamentous fungi Penicillium oxalicum and Trichoderma r	12
Recent advances and prospects of Bacillus amyloliquefaciens as microbial cell factories: from rational design to industrial applications	12
Advanced diagnostic methods for identification of bacterial foodborne pathogens: contemporary and upcoming challenges	12
An overview on fermentation strategies to overcome lignocellulosic inhibitors in second-generation ethanol production using cell immobilization	12
Spotlight on pectinase: a comprehensive review of large-scale production strategies	11
Pulmonary delivery systems for antimicrobial peptides	11
Biotechnological application of Aureobasidium spp. as a promising chassis for biosynthesis of ornithine-urea cycle-derived bioproducts	11
Application of protein engineering to ene-reductase for the synthesis of chiral compounds through asymmetric reaction	11
Advances in pharmacology, biosynthesis, and metabolic engineering of Scutellaria -specialized metabolites	11
Utilization of arbuscular mycorrhizal fungi symbiosis-related genes from host plants in biotechnology for sustainable agriculture	11
Biodegradable acids for pyrite depression and green flotation separation – an overview	11
Mitigating toxic formaldehyde to promote efficient utilization of C1 resources	11
Air biofilters for a mixture of organic gaseous pollutants: an approach for industrial applications	11
Chassis engineering for high light tolerance in microalgae and cyanobacteria	11
Exploring future applications of the apiculate yeast Hanseniaspora	10
Xylooligosaccharides mediated gut microbiome modulation: prebiotics to postbiotics	10
N -Glycosylation differences between recombinant and wildtype glycoproteins revealed by mass spectrometry	10
Fast-growing cyanobacterial chassis for synthetic biology application	10
Biocontrol of plant pathogens in omics era—with special focus on endophytic bacilli	10
Deciphering the mechanism of microalgal metabolite-protein interaction for polyhydroxyalkanoates production	10
Biosynthesis, acquisition, regulation, and upcycling of heme: recent advances	10