Cancer Investigation

Article	Citations
Clinical Characteristics and Impact on Prognosis of Melanoma Accompanied by Multiple Primary Malignancies: A Retrospective Analysis	85
Artificial Intelligence in Cancer Clinical Research: V. What We Have Learned About Human Intelligence from Artificial Intelligence	26
Use of Antiperspirant Products and Risk of Breast Cancer: A Meta-Analysis of Case-Control Studies	23
Fooled by Randomness. The Misleading Effect of Treatment Crossover in Randomized Trials of Therapies with Marginal Treatment Benefit	22
Adverse Events Induced by Nivolumab Plus Ipilimumab vs. Nivolumab Monotherapy among Cancer Patients: A Systematic Review and Meta-Analysis	20
Effect of Androgen–Androgen Receptor Directed Therapy on COVID-19 Outcome in Prostate Cancer Patients	20
Racial Diversity and Reporting in United States Food and Drug Administration Registration Trials for Thoracic Malignancies from 2006 to 2020	18
A Nomogram for Predicting Survival in Advanced Non-Small-Cell Lung Carcinoma Patients: A Population-Based Study	17
Tumor Properties Mediate the Relationship between Peripheral Blood Monocytes and Tumor-Associated Macrophages in Breast Cancer	16
COVID-19 Outbreak Impact on Cancer Multidisciplinary Team Meetings. A Multicenter French Experience	15
Development and Validation of a Nomogram for Prognosis Prediction in Patients with Synchronous Primary Thyroid and Breast Cancer Based on SEER Database	14
Clinical Analysis of the Efficacy and Safety of Different Neoadjuvant Strategies in the Treatment of Locally Advanced Rectal Cancer	13
PARP Inhibitors Rising as an Epoch-Making Strategy in First-Line Maintenance Therapy of Ovarian Cancer: A Systematic Review and Meta-Analysis	13
Clinical validation of a ctDNA-Based Assay for Multi-Cancer Detection: An Interim Report from a Vietnamese Longitudinal Prospective Cohort Study of 2795 Participants	13
Decision Aids for Decision Making about Locally Advance Breast Cancer: A Systematic Review	12
Perception, Cognition and Thought: Part I Nature, Evolution and Development of Conceptual and Symbolic Processes	11
The Democratization of Hematology-Oncology Medical Education during the COVID-19 Pandemic	11
Determinants of Post-Traumatic Growth and Quality of Life in Ghanaian Breast Cancer Survivors	10
Elevated Expression of LGR5 and WNT Signaling Factors in Neuroblastoma Cells With Acquired Drug Resistance	10
Gene Expression Analysis of Early Stage Changes in Pancreatic Cancer by Kras G12D Transfer in Pancreatic Progenitor-	10
The Relationship Between Body Image and Meaning of Life Among Women with Breast Cancer in Kerman, Iran	10
Correction	10
A Mechanistic Review of Methotrexate and Celecoxib as a Potential Metronomic Chemotherapy for Oral Squamous Cell Carcinoma	10
Long Non-Coding RNA and Chemoresistance in Bladder Cancer – A Mini Review	10
Clinical Validation of Local Versus Commercial Genomic Testing in Cancer: A Comparison of Tissue and Plasma Concordance	9

The Prevalence of Polypharmacy and Potential Drug–Drug Interactions among Iranian Cancer Patients: Which Patients were at Risk?	9
Assessing Chemotherapy-Induced Peripheral Neuropathy in Postmenopausal Breast Cancer Patients Using Vibration Perception Threshold	9
Correction	9
Webinar as an Informational Resource on Trastuzumab Biosimilars: Planning, Promotion, Execution, and Evaluation	8
Comparative Evaluation of Serum Irisin Levels in Cancer Patients and Healthy Individuals: A Systematic Review and Meta-Analysis of Diagnostic Evidence	8
Dynamic Changes of Peripheral NK Cells Predict Outcome in Patients with PD-L1 Positive Non-small-cell Lung Cancer Undergoing Immune Checkpoint Inhibitors as Second-line Therapy	8
Sepsis-related outcomes of patients with Philadelphia-negative myeloproliferative neoplasms	7
A Review on Emerging Techniques for Diagnosis of Colorectal Cancer	7
Integrative Analysis Developing and Validating Potential Candidate Biomarkers for Cancer Stemness Features of Pan-Renal Cell Carcinoma	7
Tumoral Overexpression of Hepcidin is Associated with Poor Prognosis of Patients with Clear Cell Renal Cell Carcinoma	7
Approaches for Head and Neck Cancer Research – Current Status and the Way Forward	7
Evaluation of High-Dimensional Data Classification for Skin Malignancy Detection Using DL-Based Techniques	6
The Nature, Origin and Evolution of Life: Part II The Origin of Life	6
Capecitabine-Enhanced Brachytherapy in Locally Advanced Cervical Cancer: A Phase II Non-Randomized Trial on Safety and Efficacy	6
Human Mycobiota and Its Role in Cancer Progression, Diagnostics and Therapeutics: A Link Lesser-Known	6
Early Changes in Lymphocyte/Monocyte Ratio on Treatment as a Prognostic Marker to Predict Overall Survival in Patients with Advanced Cancer Treated with Immune Checkpoint Inhibitors	6
Analytical and Clinical Validation of a Target-Enhanced Whole Genome Sequencing-Based Comprehensive Genomic Profiling Test	6
Update on Pediatric Thyroid Cancer Incidence and Mortality Trends in the United States, 2000-2018	6
p53 Missense Mutation is Associated with Immune Cell PD-L1 Expression in Triple-Negative Breast Cancer	6
Signaling Pathways Involved in 5-FU Drug Resistance in Cancer	6
An Overview of Cancer Biology, Pathophysiological Development and It’s Treatment Modalities: Current Challenges of Cancer anti-Angiogenic Therapy	6
Retrospective Analyses of PD-L1, LAG-3, TIM-3, OX40L Expressions and MSI Status in Gastroenteropancreatic Neuroendocrine Neoplasms	6
Curcumin Enhances the Efficacy of Docetaxel by Promoting Anti-Tumor Immune Response in Head and Neck Squamous Cell Carcinoma	6
Neoadjuvant Therapy and Axillary Lymph Node Status in HER2-Positive Breast Cancer	6
Fusobacterium Detected in Barrett’s Esophagus and Esophageal Adenocarcinoma Tissues	6
Engineering Novel CD19/CD22 Dual-Target CAR-T Cells for Improved Anti-Tumor Activity	5
Real World Presentation and Treatment Outcomes with a Predominant Induction Chemotherapy Based Approach in Nasopharyngeal Carcinoma: A Sixteen Year Report from a Teaching Hospital in India	5
Immunomodulation of the Breast Cancer Microenvironment by Tumor-Derived Exosomes: Implications for Immunotherapy	5
Recurrence Patterns and Clinical Management after a Positive Sentinel Node Biopsy in Melanoma Patients	5
Interplay Between ERK1/2 Signaling Pathway and Estradiol Receptor Modulates ER Targeted Genes Involved in Progression of Estrogen Responsive Breast Cancers	5
Perceptions of COVID-19 Vaccination in Patients with Genitourinary Cancers: Correspondence	5
Telomere Shortening of Barrett’s Esophagus and Esophageal Adenocarcinoma in Japanese Patients	5
Metagenomic Analysis of Biliary Microbial Flora in Patients with Gallbladder Cancer or Gallstones-Associated Chronic Cholecystitis	5
Flamingo Search Sailfish Optimizer Based SqueezeNet for Detection of Breast Cancer Using MRI Images	5
Efficacy and Safety of First-Line Platinum-Based Doublet Chemotherapy in Advanced Primary Pulmonary Salivary Gland Tumors (PSGTs)	4
Evidence-Based Medicine and Complementary and Alternative Medicine – Attitudes and Knowledge of German Medical Students	4
Increased Risk of Hyperglycemia in Advanced Urothelial Cancer Patients Treated with Enfortumab Vedotin: A Systematic Review and Meta-Analysis	4
A Comprehensive Insight into Apoptosis: Molecular Mechanisms, Signaling Pathways, and Modulating Therapeutics	4
Glucose Metabolism and Glucose Transporters in Head and Neck Squamous Cell Carcinoma	4
Perceptions of COVID-19 Vaccination in Patients with Genitourinary Cancers: A Survey Study	4
Gender, Bladder Cancer Healthcare and Burden of COVID-19	4
Fear of Cancer Recurrence and COVID-19 Anxiety Among Cancer Survivors: A Cross-Sectional Study in Southeast Iran	4
Postoperative Radiotherapy for Cutaneous Melanoma in Patients at High Risk of Local-Regional Recurrence after Surgery Alone	4
TTYH3 Promotes Cervical Cancer Progression by Activating the Wnt/ β -Catenin Signaling Pathway	4
Does Aspirin Use Reduce the Risk for Ovarian Cancer?	4
Comorbidity in Small Cell Lung Cancer: Prognostic Impacts of Hypertension/Coronary Artery Disease, Diabetes Mellitus, and Chronic Obstructive Pulmonary Disease	4
Beyond the Horizon: A Cutting-Edge Review of the Latest Checkpoint Inhibitors in Cancer Treatment	4
Cognitive Dysfunction in Non-CNS Metastatic Cancer: Comparing Brain Metastasis, Non-CNS Metastasis, and Healthy Controls	4
Trends and Projections of Stomach Cancer Incidence in Hong Kong: A Population-Based Study	4
Evaluation of Impression Cytology for Diagnosis of Ocular Surface Squamous Neoplasia in Two Kenyan Tertiary Hospitals	3

Vitamin D Receptor Expression Is Significantly Decreased in Bone Metastases Compared to Matched Primary Breast Cancer Tumours	3
Microvessel Density (MVD) in Patients with Osteosarcoma: A Systematic Review and Meta-Analysis	3
A Systematic Review of the Treatment Outcomes among Prostate Cancer Patients in Africa	3
Identifying Optimal Candidates for Primary Tumor Resection Among Metastatic Pancreatic Cancer Patients: A Population-Based Predictive Model	3
Artificial intelligence in Cancer Clinical Research: IV. Inherent Limitations of Artificial Intelligence	3
Inhibiting L1CAM Reverses Cisplatin Resistance of Triple Negative Breast Cancer Cells by Blocking AKT Signaling Pathway	3
Correction	3
Comparative Analysis of miRNA and EMT Markers in Metastatic Colorectal Cancer	3
Professional Challenges for United States Hematology/Oncology Trainees during COVID-19	3
Ethical Principles in the Analysis of Prostate Cancer Diagnostics	3
Perineural Invasion as a Predictive Biomarker of Groin Metastases and Survival Outcomes in Vulvar Cancer: A Meta-Analysis	3
Outcomes of Cancer Patients with COVID-19: The Virginia Commonwealth University Experience	3
Impacts of Perioperative Comprehensive Nursing Intervention on Postoperative Urinary Incontinence and Quality of Life of Patients Undergoing Laparoscopic Radical Prostatectomy	3
Suspension of Oncology Randomized Clinical Trials during the COVID-19 Pandemic: A Cross-Sectional Evaluation of COVID-Related Suspensions	3
Chemotherapy-Induced Oral Complications and Prophylaxis Strategies	3
Modified Le-Net Model with Multiple Image Features for Skin Cancer Detection	3
The Sledgehammer in Precision Medicine: Dexamethasone and Immunotherapeutic Treatment of Glioma	3
Prognostic Significance of Combining Cytokeratin-19, E-Cadherin and Ki-67 Analysis in Triple-Negative Breast Cancer with Basal-Like and Non-Basal-Like Phenotype	3
The Prognostic Value of ADAMTS8 and Its Role as a Tumor Suppressor in Breast Cancer	3
Barthel Index and Age as Predictors of Discharge Destination in Patients with Glioblastoma	3
Magnetic Resonance Imaging Guided Prostate Biopsy in Patients with ≥ One Negative Systematic Transrectal Ultrasound-Guided Biopsy: A Systemic Review and Meta-Analysis	3
Radiation Therapy for Primary Cutaneous Gamma Delta Lymphoma Prior to Stem Cell Transplantation	3
The Impact of Prophylactic Post-Chemotherapy G-CSF on the Relapse Rates in Patients with Acute Myeloid Leukemia: A Meta-Analysis	3
Research Progress on CARM1 and its Relationship with Colorectal Cancer	3
Ulceration vs. Mitosis in Cutaneous Melanoma: Which Is Superior for Predicting Prognosis Across Clinical Stages?	2
Clinical Characteristics and Outcomes of COVID-19 in 1294 New Cancer Patients: Single-Center, Prospective Cohort Study from Iran	2
Elevated Vitamin B12, Risk of Cancer, and Mortality: A Systematic Review	2
Three Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer: Similarities and Differences	2
Where the Sidewalk Ends: Parenting as a Trainee during COVID-19	2
PD-L1 Expression and Intra-Tumoral CD8+ T Lymphocytes in Esophageal Carcinosarcoma	2
Risk of SARS-CoV2-Related Mortality in Non-Small Cell Lung Cancer Patients Treated with First-Line Immunotherapy Alone or in Combination with Chemotherapy	2
Less is More? First Impressions From COSMIC-313	2
Medical Oncology Care – An Evolving Future	2
Exercise interventions to combat cancer-related fatigue in cancer patients undergoing treatment: a review	2
Biomarker Potential of DNA Repair Genes XRCC1, XRCC3 and RAD51 Polymorphisms in Ovarian Cancer Patients	2
Artificial Intelligence in Cancer Clinical Research: II. Development and Validation of Clinical Prediction Models	2
Drug Repurposing Analysis for Colorectal Cancer through Network Medicine Framework: Novel Candidate Drugs and Small Molecules	2
Optimizing Diagnostic Tools & Outcomes Evaluation for t (9;22)-Positive Leukemias in Pediatric Low Middle-Income Country (LMIC) Patients	2
Resilience, Social Support, and Anxious Preoccupation in Patients with Advanced Cancer during COVID-19 Pandemic	2
TTN Mutation in Endometrial Endometrioid Carcinoma Is Associated with Poor Clinical Outcomes and High Tumor Mutation Burden	2
Thyroid Cancer Detection Using Py-SpinalNet: A Pyramid and SpinalNet Approach	2
Integrated Analysis of Slow Transit Constipation and Colorectal Cancer Reveals the Co-Pathogenic Targets and Their Potential Clinical Value	2
Comparative Analysis of the Chemotherapy-Related Cognitive Impairments in Patients with Breast Cancer: A Community-Based Research	2
Sucrose Nonfermenting-Related Kinase Expression Is Related to a Metabolic Switch in Ovarian Cancer Cells That Results in Increased Fatty Acid Oxidation	2
The Roles of MicroRNA in Pancreatic Cancer Progression	2
A 15-Inflammation-Related Gene Signature Predicts the Prognosis of Patients With Pancreatic Ductal Adenocarcinoma	2
Lung Cancer Treatment Advances in 2022	2
The Journey of Resveratrol from Vineyards to Clinics	2
Grade 4 Neutropenia Frequency as a Binary Risk Predictor for Adverse Clinical Consequences of Chemotherapy‑Induced Neutropenia: A Meta-analysis	2
The Use of Modified Surrogate End Points in Cancer Clinical Trials	2
LDHB Mediates Histone Lactylation to Activate PD-L1 and Promote Ovarian Cancer Immune Escape	2
The Pittsburgh Sleep Quality Index (PSQI) Applied to Cancer Patients: Psychometric Properties and Factors Affecting Sleep Quality	2
An Introduction to the Relationship Between Lewis x and Malignancy Mainly Related to Breast Cancer and Head Neck Squamous Cell Carcinoma (HNSCC)	2
Variation of Plasma Damage-Associated Molecular Patterns in Patients with Advanced Solid Tumors after Standard of Care Systemic Treatment	2
Veliparib‑Induced Toxicity in Cancer Patients: A Systematic Review and Meta‑Analysis	2
AURKA Enhances Antitumor Immunity by Activating CD4+ T Cell Proliferation in Colorectal Cancer	2
Spine Instability Neoplastic Score (SINS) as a Predictive Tool in Conventional Radiotherapy: A Narrative Review	2
Conceptualization of Breast Cancer and Attitudes toward Breast Cancer Screening: A Qualitative Study on Iranian and Australian Women	1
The Effect of Hypnosis on the Intensity of Pain and Anxiety in Cancer Patients: A Systematic Review of Controlled Experimental Trials	1
Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Concurrent Use of Crocin During Chemoradiation for Esophageal Squamous Cell Carcinoma	1
Metabolism-Related Programmed Cell Death: Unveiling Prognostic Biomarkers, Immune Checkpoints, and Therapeutic Strategies in Ovarian Cancer	1
Development of a Novel Prognostic Model for Esophageal Squamous Cell Carcinoma: Insights into Immune Cell Interactions and Drug Sensitivity	1
Rapid Progress in Intelligent Radiotherapy and Future Implementation	1
Attenuated Total Reflection-Fourier Transform Infrared (ATR-FTIR) Spectroscopy Analysis of Saliva as a Diagnostic Specimen for Rapid Classification of Oral Squamous Cell Carcinoma Using Chemometrics M	1
Suitability of Metastatic Lung Tumors for Stereotactic Body Radiotherapy	1
Tandem Dual CAR-T Cells Targeting HER2 and Mesothelin Enhance anti-Tumor Effects in Pancreatic Cancer	1
Immune-related Liver Injury is a Poor Prognostic Factor in Patients with Nonsmall Cell Lung Cancer Treated with Immune Checkpoint Inhibitors	1
Cancer Patients’ Unmet Needs in Three Low- to Middle- Income Countries: Perspectives from Health Care Providers	1
The Nature, Origin, and Evolution of Life: Part IV Cellular Differentiation and the Emergence of Multicellular Life	1
Once-a-Week Ablative Radiotherapy as Replacement of Prolonged Fractionation in Frail Patients: Feasibility and Toxicity Results	1
Tertiary Lymphoid Structures, Immune Response, and Prognostic Relevance in Non-Small Cell Lung Cancer	1
Efficacy and Safety of Current Treatment Regimens for Acute Myeloid Leukemia in Elderly Patients	1
Decoding Cervical Cancer Biomarkers: An Integrated Framework of Bioinformatics, Machine Learning, and Experimental Confirmation	1
Poorly Controlled Diabetes Mellitus Increases the Risk of Deaths and Castration-Resistance in Locally Advanced Prostate Cancer Patients	1
Efficacy of Adjuvant First-Generation TKIs versus Chemotherapy in Patients with Completely Resected EGFR-Mutant Non-Small Cell Lung Cancer: A Meta-Analysis	1
Gustative Roussy Immune Score is a Predictor for Major Pathological Response in Rectal Cancer: A Result from the Preoperative Intraarterial Chemoembolization Combined with Radiotherapy (PCAR) Study	1
The Nature, Origin, and Evolution of Life: Part V Bringing It Together: Concepts, Constraints, and Closure	1
Late Mortality in Childhood Cancer Survivors according to Pediatric Cancer Diagnosis and Treatment Era in the Dutch LATER Cohort	1
Viral Hepatitis in Western Patients with Advanced Intrahepatic Cholangiocarcinoma: Retrospective Assessment of Prevalence, Prognostic and Predictive Significance	1
Routine Skin Cancer Screening: Balance between Overdiagnosis and Prevention	1

Social Support as a Protective Factor for Patients with Cancer during the Pandemic	1
Characteristics of Invasive Cribriform Carcinoma	1
Chronic Inflammation and Cancer: Key Pathways and Targeted Therapies	1
Accuracy of the ‘CUT’ Score for Assessing Malignancy in Bethesda 3 and 4 Thyroid Nodules in North American Population: A Retrospective Study	1
Perception, Cognition and Thought: Part III: Reasoning, Judgement and Decision-Making	1
Evaluation of the Efficacy of Postoperative Adjuvant Therapy for HER2-Positive Ductal Carcinoma in Situ with Microinvasion	1
Pathology Reports: Discrepancy Patterns of Second Opinions in a Referral Cancer Center	1
Management of Non-Small Cell Lung Cancer: Updates from the European Lung Cancer Congress 2022	1
Anxiety, Depression, and Coping Strategies during Chemotherapy Treatment: A Comparison of Older and Younger Adults with Advanced Cancer in Brazil	1
Multi-Modal Lung Cancer Detection Using Pyramidal Cascade Neuro-Fuzzy Fractional Network	1
Examining the Direct and Indirect Effects of Socioeconomic Status on Colorectal Cancer Using Structural Equation Modeling	1
Application in Gene Editing in Ovarian Cancer Therapy	1
Clinical Challenges and Evolving Treatments in Desmoid Fibromatosis: A Single Institution Experience	1
The Markers Auxiliary in Differential Diagnosis of Early Melanomas and Benign Nevi Sharing Some Similar Features Potentially Leading to Misdiagnosis – A Review of Immunohistochemical Studies	1
Impact of the Multidisciplinary Cancer Team on the Diagnostic and Therapeutic Care Pathway of Early Breast Cancer Patients and Perception of Team Members: The Experience of a Cancer Centre in Italy	1
Predictive Modeling of Long-Term Prognosis After Resection in Typical Pulmonary Carcinoid: A Machine Learning Perspective	1
International Society of Urological Pathology (ISUP)-Grade Grouping in Prostatic Adenocarcinoma and its Prognostic Implications	1
Tumor Differentiation as a Prognostic Marker in Clinically Staged T1bN0 Esophageal Adenocarcinoma	1
A Bioinformatic Analysis of Gut Microbiota Related with Immune Cell Infiltration in Colorectal Cancer	1
Genomic Alterations of Signaling and DNA Damage Repair Pathways in Non-Muscle Invasive Bladder Cancer	1
Prognostic Effects of Sarcopenia on Patients with Bladder Cancer: A Systematic Review and Meta-Analysis	1
Self-Supervised Learning Method for Breast Cancer Detection with Image Feature Set and Modified U-Net Segmentation Using Whole Slide Image	1
Metastasis to Breast from Extramammary Solid Tumors and Lymphomas: A 20-Year Population-Based Study	1