Biotechnology Advances

(The TQCC of Biotechnology Advances is 30. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
Stabilization of enzymes via immobilization: Multipoint covalent attachment and other stabilization strategies284
Using machine learning approaches for multi-omics data analysis: A review274
A review of high value-added molecules production by microalgae in light of the classification272
Microalgae as a future food source263
Fungal potential for the degradation of petroleum-based polymers: An overview of macro- and microplastics biodegradation227
The challenge and prospect of mRNA therapeutics landscape219
The approved gene therapy drugs worldwide: from 1998 to 2019214
Technologies for biological removal and recovery of nitrogen from wastewater197
Extracellular matrix-derived biomaterials in engineering cell function165
Enzyme co-immobilization: Always the biocatalyst designers' choice…or not?145
Bacterial cellulose micro-nano fibres for wound healing applications144
Lignin nanoparticles enter the scene: A promising versatile green tool for multiple applications127
Molecular priming as an approach to induce tolerance against abiotic and oxidative stresses in crop plants120
Microbial extracellular electron transfer and strategies for engineering electroactive microorganisms118
Genetic engineering of microalgae for enhanced biorefinery capabilities116
Molecular farming – The slope of enlightenment114
Microbial enzymes catalyzing keratin degradation: Classification, structure, function111
Biotechnological potential and applications of microbial consortia110
Microbial electrosynthesis: Towards sustainable biorefineries for production of green chemicals from CO2 emissions110
Biotechnological production of astaxanthin from the microalga Haematococcus pluvialis109
Fermentation transforms the phenolic profiles and bioactivities of plant-based foods108
Biopolymer-liposome hybrid systems for controlled delivery of bioactive compounds: Recent advances108
Purple phototrophic bacteria for resource recovery: Challenges and opportunities103
Recent developments in the use of peroxygenases – Exploring their high potential in selective oxyfunctionalisations102
Consolidated bio-saccharification: Leading lignocellulose bioconversion into the real world102
Algae biostimulants: A critical look at microalgal biostimulants for sustainable agricultural practices100
Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications99
Mammalian cell culture for production of recombinant proteins: A review of the critical steps in their biomanufacturing98
Biodegradation and up-cycling of polyurethanes: Progress, challenges, and prospects97
Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts94
Potential of phytohormones as a strategy to improve microalgae productivity for biotechnological applications92
Microbial melanin: Recent advances in biosynthesis, extraction, characterization, and applications90
Adaptive laboratory evolution principles and applications in industrial biotechnology86
Prospects and development of algal-bacterial biotechnology in environmental management and protection85
Library preparation for next generation sequencing: A review of automation strategies84
Glycoside hydrolase family 18 chitinases: The known and the unknown82
Biological production of medium-chain carboxylates through chain elongation: An overview79
Neural tissue engineering with structured hydrogels in CNS models and therapies78
The invisible life inside plants: Deciphering the riddles of endophytic bacterial diversity78
Flavoprotein monooxygenases: Versatile biocatalysts77
Biodegradation of polyethylene and polystyrene: From microbial deterioration to enzyme discovery76
Expanding the chemical diversity through microorganisms co-culture: Current status and outlook74
Ecofriendly biopolymers and composites: Preparation and their applications in water-treatment73
Lipase immobilization on ceramic supports: An overview on techniques and materials71
The Yin and Yang of exosome isolation methods: conventional practice, microfluidics, and commercial kits71
Nanostructured antimicrobial peptides: The last push towards clinics71
Metabolic engineering of Saccharomyces cerevisiae for the production of top value chemicals from biorefinery carbohydrates69
Vero cell upstream bioprocess development for the production of viral vectors and vaccines68
Strategies to manipulate the performance of aptamers in SELEX, post-SELEX and microenvironment67
Pseudomonas aeruginosa biofilms and their partners in crime67
Biomaterializing the promise of cardiac tissue engineering67
Archaea Biotechnology67
Consolidated bioprocessing of raw starch to ethanol by Saccharomyces cerevisiae: Achievements and challenges65
Developing Aspergillus niger as a cell factory for food enzyme production64
Iron-assisted biological wastewater treatment: Synergistic effect between iron and microbes64
Current and novel approaches to downstream processing of microalgae: A review63
Antimicrobial properties and applications of metal nanoparticles biosynthesized by green methods62
Bacterial cellulose and its potential for biomedical applications62
Anthocyanins, multi-functional natural products of industrial relevance: Recent biotechnological advances61
Production of plant natural products through engineered Yarrowia lipolytica61
Molecularly imprinted polymers for the selective recognition of microorganisms61
Prospects on bio-based 2,3-butanediol and acetoin production: Recent progress and advances60
Current trends in the production of biodegradable bioplastics: The case of polyhydroxyalkanoates60
Acetate as a potential feedstock for the production of value-added chemicals: Metabolism and applications58
Biotechnological production of lipid and terpenoid from thraustochytrids57
Strategies employed in the design of antimicrobial peptides with enhanced proteolytic stability56
Inspired by nature: Microbial production, degradation and valorization of biodegradable bioplastics for life-cycle-engineered products56
Microbial production of limonene and its derivatives: Achievements and perspectives55
Alternative sources and metabolic engineering of Taxol: Advances and future perspectives54
Microalgae with artificial intelligence: A digitalized perspective on genetics, systems and products54
Challenges in biodegradation of non-degradable thermoplastic waste: From environmental impact to operational readiness54
Advances in the profiling of N6-methyladenosine (m6A) modifications53
Downstream processing technologies in the biocatalytic production of oligosaccharides53
Biological and conventional food processing modifications on food proteins: Structure, functionality, and bioactivity53
Biotechnological approaches for the production of natural colorants by Talaromyces/Penicillium: A review52
Genetic engineering of microalgae for enhanced lipid production52
A comprehensive and critical review on key elements to implement enzymatic PET depolymerization for recycling purposes52
Computational design of enzymes for biotechnological applications51
Flavonoids, terpenoids, and polyketide antibiotics: Role of glycosylation and biocatalytic tactics in engineering glycosylation50
Boosting extracellular vesicle secretion50
Review of advances in the development of laccases for the valorization of lignin to enable the production of lignocellulosic biofuels and bioproducts50
Stress response in Rhodococcus strains50
Self-assembling peptide-based hydrogels: Fabrication, properties, and applications49
Whole-cell biocatalysis using cytochrome P450 monooxygenases for biotransformation of sustainable bioresources (fatty acids, fatty alkanes, and aromatic amino acids)49
Sperm selection in assisted reproduction: A review of established methods and cutting-edge possibilities49
Understanding gradients in industrial bioreactors49
A navigation guide of synthetic biology tools for Pseudomonas putida48
Review: Remotely controlled magneto-regulation of therapeutics from magnetoelastic gel matrices47
Smart microalgae farming with internet-of-things for sustainable agriculture47
Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics46
Mechanical properties of single cells: Measurement methods and applications46
How does the Internet of Things (IoT) help in microalgae biorefinery?45
How can ethanol enhance direct interspecies electron transfer in anaerobic digestion?45
Bio-synthesis of food additives and colorants-a growing trend in future food45
Trends in the development of innovative nanobiocatalysts and their application in biocatalytic transformations45
Production of polyunsaturated fatty acids by Schizochytrium (Aurantiochytrium) spp.44
Engineering of Saccharomyces cerevisiae as a consolidated bioprocessing host to produce cellulosic ethanol: Recent advancements and current challenges44
Algal metabolites: An inevitable substitute for antibiotics43
Unlocking the secret of lignin-enzyme interactions: Recent advances in developing state-of-the-art analytical techniques43
Ionic liquids for regulating biocatalytic process: Achievements and perspectives42
Can anaerobic digestion be a suitable end-of-life scenario for biodegradable plastics? A critical review of the current situation, hurdles, and challenges42
Biotechnological production and high potential of furan-based renewable monomers and polymers42
Recent trends in methane to bioproduct conversion by methanotrophs41
On the verge of the market – Plant factories for the automated and standardized production of biopharmaceuticals41
Next-generation metabolic engineering approaches towards development of plant cell suspension cultures as specialized metabolite producing biofactories41
Amidase as a versatile tool in amide-bond cleavage: From molecular features to biotechnological applications40
Physical methods for controlling bacterial colonization on polymer surfaces40
Biopolymers production from microalgae and cyanobacteria cultivated in wastewater: Recent advances40
Biotransformation of dietary phytoestrogens by gut microbes: A review on bidirectional interaction between phytoestrogen metabolism and gut microbiota40
Recent advances in lipid metabolic engineering of oleaginous yeasts40
What do we learn from enzyme behaviors in organic solvents? – Structural functionalization of ionic liquids for enzyme activation and stabilization40
Biofilm control by interfering with c-di-GMP metabolism and signaling40
A review on the progress, challenges and prospects in commercializing microalgal fucoxanthin39
Pathogens and predators impacting commercial production of microalgae and cyanobacteria39
Microbial starch debranching enzymes: Developments and applications39
Plant synthetic biology for producing potent phyto-antimicrobials to combat antimicrobial resistance39
From bumblebee to bioeconomy: Recent developments and perspectives for sophorolipid biosynthesis38
Bacterial and enzymatic degradation of poly(cis-1,4-isoprene) rubber: Novel biotechnological applications38
Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds38
Biocatalytic oxidation of fatty alcohols into aldehydes for the flavors and fragrances industry38
Harnessing cells to deliver nanoparticle drugs to treat cancer38
Engineer probiotic bifidobacteria for food and biomedical applications - Current status and future prospective37
Extremophilic lipases for industrial applications: A general review37
Waste-to-nutrition: a review of current and emerging conversion pathways37
Mycolicibacterium cell factory for the production of steroid-based drug intermediates37
Models of microalgal cultivation for added-value products - A review37
Marine drugs: Biology, pipelines, current and future prospects for production36
Refactoring transcription factors for metabolic engineering36
Electro-fermentation: Sustainable bioproductions steered by electricity36
Anodic electro-fermentation: Empowering anaerobic production processes via anodic respiration36
Current status and future prospects in cannabinoid production through in vitro culture and synthetic biology35
Insights on the emerging biotechnology of histidine-rich peptides35
Predicting drug-microbiome interactions with machine learning35
Hot spots-making directed evolution easier35
Developing fungal heterologous expression platforms to explore and improve the production of natural products from fungal biodiversity35
Chemical modification of enzymes to improve biocatalytic performance34
Non-viral transfection technologies for next-generation therapeutic T cell engineering33
Biotechnological applications of the non-conventional yeast Meyerozyma guilliermondii33
From lignocellulose to plastics: Knowledge transfer on the degradation approaches by fungi33
Cyanobacteria and microalgae in supporting human habitation on Mars32
Advances in enzymatic oxyfunctionalization of aliphatic compounds32
Adaptive defensive mechanism of bioleaching microorganisms under extremely environmental acid stress: Advances and perspectives32
Marine macroalgae in a circular economy context: A comprehensive analysis focused on residual biomass32
Towards efficient enzymatic saccharification of pretreated lignocellulose: Enzyme inhibition by lignin-derived phenolics and recent trends in mitigation strategies32
Strategies for improving antimicrobial peptide production31
Microbial-enabled green biosynthesis of nanomaterials: Current status and future prospects31
Genetic control of grain appearance quality in rice31
Common problems associated with the microbial productions of aromatic compounds and corresponding metabolic engineering strategies31
Engineering whole-cell microbial biosensors: Design principles and applications in monitoring and treatment of heavy metals and organic pollutants31
Dehydrogenases of acetic acid bacteria31
Comparative analysis of the chemical and biochemical synthesis of keto acids30
Biofilm application in the microbial biochemicals production process30
The tale of a versatile enzyme: Molecular insights into keratinase for its industrial dissemination30
Microbial chassis engineering drives heterologous production of complex secondary metabolites30
Lipid metabolism research in oleaginous fungus Mortierella alpina: Current progress and future prospects30
Recent advancements and challenges in emerging applications of biochar-based catalysts30
Phosphorylase-catalyzed bottom-up synthesis of short-chain soluble cello-oligosaccharides and property-tunable cellulosic materials30
Controlling biofilms using synthetic biology approaches30