Biotechnology Advances

Article	Citations
Using machine learning approaches for multi-omics data analysis: A review	377
Stabilization of enzymes via immobilization: Multipoint covalent attachment and other stabilization strategies	350
Technologies for biological removal and recovery of nitrogen from wastewater	267
Enzyme co-immobilization: Always the biocatalyst designers' choice…or not?	161
Lignin nanoparticles enter the scene: A promising versatile green tool for multiple applications	161
Microbial extracellular electron transfer and strategies for engineering electroactive microorganisms	156
Fermentation transforms the phenolic profiles and bioactivities of plant-based foods	155
Microbial electrosynthesis: Towards sustainable biorefineries for production of green chemicals from CO2 emissions	137
Microbial enzymes catalyzing keratin degradation: Classification, structure, function	135
Algae biostimulants: A critical look at microalgal biostimulants for sustainable agricultural practices	133
Biopolymer-liposome hybrid systems for controlled delivery of bioactive compounds: Recent advances	132
Genetic engineering of microalgae for enhanced biorefinery capabilities	131
Biodegradation and up-cycling of polyurethanes: Progress, challenges, and prospects	124
Biotechnological production of astaxanthin from the microalga Haematococcus pluvialis	123
Mammalian cell culture for production of recombinant proteins: A review of the critical steps in their biomanufacturing	123
Recent developments in the use of peroxygenases – Exploring their high potential in selective oxyfunctionalisations	120
Biodegradation of polyethylene and polystyrene: From microbial deterioration to enzyme discovery	119
Purple phototrophic bacteria for resource recovery: Challenges and opportunities	119
Microbial melanin: Recent advances in biosynthesis, extraction, characterization, and applications	113
Potential of phytohormones as a strategy to improve microalgae productivity for biotechnological applications	112
Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts	106
Adaptive laboratory evolution principles and applications in industrial biotechnology	106
Biological production of medium-chain carboxylates through chain elongation: An overview	102
Prospects and development of algal-bacterial biotechnology in environmental management and protection	100
Flavoprotein monooxygenases: Versatile biocatalysts	94

Glycoside hydrolase family 18 chitinases: The known and the unknown	93
Ecofriendly biopolymers and composites: Preparation and their applications in water-treatment	91
Pseudomonas aeruginosa biofilms and their partners in crime	89
The Yin and Yang of exosome isolation methods: conventional practice, microfluidics, and commercial kits	88
Strategies to manipulate the performance of aptamers in SELEX, post-SELEX and microenvironment	88
Archaea Biotechnology	86
The invisible life inside plants: Deciphering the riddles of endophytic bacterial diversity	86
Vero cell upstream bioprocess development for the production of viral vectors and vaccines	86
Bacterial cellulose and its potential for biomedical applications	84
Nanostructured antimicrobial peptides: The last push towards clinics	84
Antimicrobial properties and applications of metal nanoparticles biosynthesized by green methods	84
Prospects on bio-based 2,3-butanediol and acetoin production: Recent progress and advances	82
Anthocyanins, multi-functional natural products of industrial relevance: Recent biotechnological advances	81
Developing Aspergillus niger as a cell factory for food enzyme production	81
Metabolic engineering of Saccharomyces cerevisiae for the production of top value chemicals from biorefinery carbohydrates	80
Iron-assisted biological wastewater treatment: Synergistic effect between iron and microbes	80
Strategies employed in the design of antimicrobial peptides with enhanced proteolytic stability	75
Current and novel approaches to downstream processing of microalgae: A review	75
Boosting extracellular vesicle secretion	74
A comprehensive and critical review on key elements to implement enzymatic PET depolymerization for recycling purposes	72
Molecularly imprinted polymers for the selective recognition of microorganisms	72
Microbial production of limonene and its derivatives: Achievements and perspectives	72
Production of plant natural products through engineered Yarrowia lipolytica	70
Inspired by nature: Microbial production, degradation and valorization of biodegradable bioplastics for life-cycle-engineered products	69
Acetate as a potential feedstock for the production of value-added chemicals: Metabolism and applications	69
Challenges in biodegradation of non-degradable thermoplastic waste: From environmental impact to operational readiness	67
Review of advances in the development of laccases for the valorization of lignin to enable the production of lignocellulosic biofuels and bioproducts	67
Computational design of enzymes for biotechnological applications	65
Advances in the profiling of N6-methyladenosine (m6A) modifications	64
Stress response in Rhodococcus strains	64
Genetic engineering of microalgae for enhanced lipid production	64
Microalgae with artificial intelligence: A digitalized perspective on genetics, systems and products	63
Amidase as a versatile tool in amide-bond cleavage: From molecular features to biotechnological applications	61
Biotechnological production of lipid and terpenoid from thraustochytrids	61
Recent trends in methane to bioproduct conversion by methanotrophs	61
Recent advancements and challenges in emerging applications of biochar-based catalysts	61
Understanding gradients in industrial bioreactors	61
Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics	61
Downstream processing technologies in the biocatalytic production of oligosaccharides	59
A navigation guide of synthetic biology tools for Pseudomonas putida	59
Self-assembling peptide-based hydrogels: Fabrication, properties, and applications	58
Biotechnological approaches for the production of natural colorants by Talaromyces/Penicillium: A review	58
Alternative sources and metabolic engineering of Taxol: Advances and future perspectives	56
Bio-synthesis of food additives and colorants-a growing trend in future food	56
Mechanical properties of single cells: Measurement methods and applications	56
Biofilm control by interfering with c-di-GMP metabolism and signaling	55
Production of polyunsaturated fatty acids by Schizochytrium (Aurantiochytrium) spp.	55
How can ethanol enhance direct interspecies electron transfer in anaerobic digestion?	55
On the verge of the market – Plant factories for the automated and standardized production of biopharmaceuticals	54
Biotechnological production and high potential of furan-based renewable monomers and polymers	54

Pathogens and predators impacting commercial production of microalgae and cyanobacteria	54
How does the Internet of Things (IoT) help in microalgae biorefinery?	54
Smart microalgae farming with internet-of-things for sustainable agriculture	54
Unlocking the secret of lignin-enzyme interactions: Recent advances in developing state-of-the-art analytical techniques	54
Review: Remotely controlled magneto-regulation of therapeutics from magnetoelastic gel matrices	53
Engineering of Saccharomyces cerevisiae as a consolidated bioprocessing host to produce cellulosic ethanol: Recent advancements and current challenges	53
Can anaerobic digestion be a suitable end-of-life scenario for biodegradable plastics? A critical review of the current situation, hurdles, and challenges	53
Extremophilic lipases for industrial applications: A general review	52
Engineering whole-cell microbial biosensors: Design principles and applications in monitoring and treatment of heavy metals and organic pollutants	52
Trends in the development of innovative nanobiocatalysts and their application in biocatalytic transformations	51
Strategies for improving antimicrobial peptide production	51
Next-generation metabolic engineering approaches towards development of plant cell suspension cultures as specialized metabolite producing biofactories	51
Biopolymers production from microalgae and cyanobacteria cultivated in wastewater: Recent advances	51
Hot spots-making directed evolution easier	51
Biocatalytic oxidation of fatty alcohols into aldehydes for the flavors and fragrances industry	50
Algal metabolites: An inevitable substitute for antibiotics	50
Genetic control of grain appearance quality in rice	49
A review on the progress, challenges and prospects in commercializing microalgal fucoxanthin	49
What do we learn from enzyme behaviors in organic solvents? – Structural functionalization of ionic liquids for enzyme activation and stabilization	48
Plant synthetic biology for producing potent phyto-antimicrobials to combat antimicrobial resistance	48
Cyanobacteria and microalgae in supporting human habitation on Mars	48
From bumblebee to bioeconomy: Recent developments and perspectives for sophorolipid biosynthesis	47
Refactoring transcription factors for metabolic engineering	47
From lignocellulose to plastics: Knowledge transfer on the degradation approaches by fungi	47
Ionic liquids for regulating biocatalytic process: Achievements and perspectives	47
Microbial starch debranching enzymes: Developments and applications	46
Recent advances in lipid metabolic engineering of oleaginous yeasts	46
Physical methods for controlling bacterial colonization on polymer surfaces	46
Waste-to-nutrition: a review of current and emerging conversion pathways	46
Engineer probiotic bifidobacteria for food and biomedical applications - Current status and future prospective	45
Biotransformation of dietary phytoestrogens by gut microbes: A review on bidirectional interaction between phytoestrogen metabolism and gut microbiota	45
Current status and future prospects in cannabinoid production through in vitro culture and synthetic biology	45
Marine drugs: Biology, pipelines, current and future prospects for production	45
Electro-fermentation: Sustainable bioproductions steered by electricity	44
Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds	44
Chemical modification of enzymes to improve biocatalytic performance	44
Mycolicibacterium cell factory for the production of steroid-based drug intermediates	44
Bacterial volatile organic compounds as biopesticides, growth promoters and plant-defense elicitors: Current understanding and future scope	44
Bacterial and enzymatic degradation of poly(cis-1,4-isoprene) rubber: Novel biotechnological applications	44
Opportunities and challenges of the tag-assisted protein purification techniques: Applications in the pharmaceutical industry	43
Microbial-enabled green biosynthesis of nanomaterials: Current status and future prospects	43
Predicting drug-microbiome interactions with machine learning	42
Exploitation of lignocellulosic-based biomass biorefinery: A critical review of renewable bioresource, sustainability and economic views	41
Biotechnological applications of the non-conventional yeast Meyerozyma guilliermondii	41
Marine macroalgae in a circular economy context: A comprehensive analysis focused on residual biomass	40
Anodic electro-fermentation: Empowering anaerobic production processes via anodic respiration	40
Lactic acid bacteria-derived α-glucans: From enzymatic synthesis to miscellaneous applications	40
Cellulose- and xylan-degrading yeasts: Enzymes, applications and biotechnological potential	40
Towards efficient enzymatic saccharification of pretreated lignocellulose: Enzyme inhibition by lignin-derived phenolics and recent trends in mitigation strategies	40
Developing fungal heterologous expression platforms to explore and improve the production of natural products from fungal biodiversity	39
Models of microalgal cultivation for added-value products - A review	39
Insights on the emerging biotechnology of histidine-rich peptides	39
Non-viral transfection technologies for next-generation therapeutic T cell engineering	39
Lipid metabolism research in oleaginous fungus Mortierella alpina: Current progress and future prospects	38
Biomass directional pyrolysis based on element economy to produce high-quality fuels, chemicals, carbon materials – A review	38
Bacterial membrane vesicle functions, laboratory methods, and applications	38
Has the time finally come for green oleochemicals and biodiesel production using large-scale enzyme technologies? Current status and new developments	37
Xylanases of glycoside hydrolase family 30 – An overview	37
Noble metal nanoparticles in agriculture: impacts on plants, associated microorganisms, and biotechnological practices	37
Surrogate broodstock to enhance biotechnology research and applications in aquaculture	37
Comparative analysis of the chemical and biochemical synthesis of keto acids	37
Type II methanotrophs: A promising microbial cell-factory platform for bioconversion of methane to chemicals	37
Dehydrogenases of acetic acid bacteria	37
The tale of a versatile enzyme: Molecular insights into keratinase for its industrial dissemination	37
Biopolymers and their derivatives: Key components of advanced biomedical technologies	37
Rhodopseudomonas palustris: A biotechnology chassis	37
Agrobacterium strains and strain improvement: Present and outlook	37
From fungal secretomes to enzymes cocktails: The path forward to bioeconomy	37
Advances and perspectives on mass transfer and enzymatic hydrolysis in the enzyme-mediated lignocellulosic biorefinery: A review	36
Biofilm application in the microbial biochemicals production process	36
Phosphorylase-catalyzed bottom-up synthesis of short-chain soluble cello-oligosaccharides and property-tunable cellulosic materials	35
Bacillus licheniformis: The unexplored alternative for the anaerobic production of lipopeptide biosurfactants?	35
Insertions and deletions in protein evolution and engineering	35
Microbial chassis engineering drives heterologous production of complex secondary metabolites	35
Advances in enzymatic oxyfunctionalization of aliphatic compounds	35
Bionanomaterials based on protein self-assembly: Design and applications in biotechnology	34
Recent advances in fed-batch microscale bioreactor design	34
4D printing: Perspectives for the production of sustainable plastics for agriculture	34
Data mining of Saccharomyces cerevisiae mutants engineered for increased tolerance towards inhibitors in lignocellulosic hydrolysates	34
Microbial inhibition and biosensing with multifunctional carbon dots: Progress and perspectives	34

Synthetic biology-inspired strategies and tools for engineering of microbial natural product biosynthetic pathways	34
Genetically encoded biosensors for microbial synthetic biology: From conceptual frameworks to practical applications	33
Agarose degradation for utilization: Enzymes, pathways, metabolic engineering methods and products	33
Progress in biohythane production from microalgae-wastewater sludge co-digestion: An integrated biorefinery approach	32
Bacterial membrane transporter systems for aromatic compounds: Regulation, engineering, and biotechnological applications	32
Towards Green Nanoscience: From extraction to nanoformulation	32
Photocatalyst-enzyme hybrid systems for light-driven biotransformation	32
Engineering of primary carbon metabolism in filamentous fungi	32
Computer-aided understanding and engineering of enzymatic selectivity	32
An overview and future prospects of sialic acids	32