Biotechnology Advances

Article	Citations
Using machine learning approaches for multi-omics data analysis: A review	329
Stabilization of enzymes via immobilization: Multipoint covalent attachment and other stabilization strategies	327
Microalgae as a future food source	287
A review of high value-added molecules production by microalgae in light of the classification	287
Technologies for biological removal and recovery of nitrogen from wastewater	229
Extracellular matrix-derived biomaterials in engineering cell function	185
Enzyme co-immobilization: Always the biocatalyst designers' choice…or not?	159
Bacterial cellulose micro-nano fibres for wound healing applications	158
Lignin nanoparticles enter the scene: A promising versatile green tool for multiple applications	148
Microbial extracellular electron transfer and strategies for engineering electroactive microorganisms	140
Fermentation transforms the phenolic profiles and bioactivities of plant-based foods	136
Microbial enzymes catalyzing keratin degradation: Classification, structure, function	127
Microbial electrosynthesis: Towards sustainable biorefineries for production of green chemicals from CO2 emissions	125
Biopolymer-liposome hybrid systems for controlled delivery of bioactive compounds: Recent advances	125
Genetic engineering of microalgae for enhanced biorefinery capabilities	124
Algae biostimulants: A critical look at microalgal biostimulants for sustainable agricultural practices	119
Biotechnological production of astaxanthin from the microalga Haematococcus pluvialis	116
Biodegradation and up-cycling of polyurethanes: Progress, challenges, and prospects	115
Recent developments in the use of peroxygenases – Exploring their high potential in selective oxyfunctionalisations	112
Mammalian cell culture for production of recombinant proteins: A review of the critical steps in their biomanufacturing	111
Purple phototrophic bacteria for resource recovery: Challenges and opportunities	110
Microbial melanin: Recent advances in biosynthesis, extraction, characterization, and applications	103
Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts	102
Potential of phytohormones as a strategy to improve microalgae productivity for biotechnological applications	102
Biodegradation of polyethylene and polystyrene: From microbial deterioration to enzyme discovery	99

Adaptive laboratory evolution principles and applications in industrial biotechnology	99
Library preparation for next generation sequencing: A review of automation strategies	93
Prospects and development of algal-bacterial biotechnology in environmental management and protection	92
Neural tissue engineering with structured hydrogels in CNS models and therapies	90
Glycoside hydrolase family 18 chitinases: The known and the unknown	88
Flavoprotein monooxygenases: Versatile biocatalysts	88
Biological production of medium-chain carboxylates through chain elongation: An overview	86
Strategies to manipulate the performance of aptamers in SELEX, post-SELEX and microenvironment	81
The invisible life inside plants: Deciphering the riddles of endophytic bacterial diversity	81
The Yin and Yang of exosome isolation methods: conventional practice, microfluidics, and commercial kits	81
Nanostructured antimicrobial peptides: The last push towards clinics	80
Ecofriendly biopolymers and composites: Preparation and their applications in water-treatment	79
Archaea Biotechnology	77
Pseudomonas aeruginosa biofilms and their partners in crime	77
Developing Aspergillus niger as a cell factory for food enzyme production	77
Metabolic engineering of Saccharomyces cerevisiae for the production of top value chemicals from biorefinery carbohydrates	76
Vero cell upstream bioprocess development for the production of viral vectors and vaccines	76
Antimicrobial properties and applications of metal nanoparticles biosynthesized by green methods	76
Bacterial cellulose and its potential for biomedical applications	75
Anthocyanins, multi-functional natural products of industrial relevance: Recent biotechnological advances	74
Lipase immobilization on ceramic supports: An overview on techniques and materials	74
Iron-assisted biological wastewater treatment: Synergistic effect between iron and microbes	73
Prospects on bio-based 2,3-butanediol and acetoin production: Recent progress and advances	72
Biomaterializing the promise of cardiac tissue engineering	71
Current and novel approaches to downstream processing of microalgae: A review	70
Consolidated bioprocessing of raw starch to ethanol by Saccharomyces cerevisiae: Achievements and challenges	68
Current trends in the production of biodegradable bioplastics: The case of polyhydroxyalkanoates	67
Microbial production of limonene and its derivatives: Achievements and perspectives	67
Strategies employed in the design of antimicrobial peptides with enhanced proteolytic stability	67
Molecularly imprinted polymers for the selective recognition of microorganisms	65
Production of plant natural products through engineered Yarrowia lipolytica	65
Acetate as a potential feedstock for the production of value-added chemicals: Metabolism and applications	64
Inspired by nature: Microbial production, degradation and valorization of biodegradable bioplastics for life-cycle-engineered products	63
Boosting extracellular vesicle secretion	63
A comprehensive and critical review on key elements to implement enzymatic PET depolymerization for recycling purposes	63
Challenges in biodegradation of non-degradable thermoplastic waste: From environmental impact to operational readiness	62
Review of advances in the development of laccases for the valorization of lignin to enable the production of lignocellulosic biofuels and bioproducts	59
Genetic engineering of microalgae for enhanced lipid production	59
Microalgae with artificial intelligence: A digitalized perspective on genetics, systems and products	59
Biotechnological production of lipid and terpenoid from thraustochytrids	58
Advances in the profiling of N6-methyladenosine (m6A) modifications	58
Stress response in Rhodococcus strains	58
Computational design of enzymes for biotechnological applications	57
Flavonoids, terpenoids, and polyketide antibiotics: Role of glycosylation and biocatalytic tactics in engineering glycosylation	56
Biotechnological approaches for the production of natural colorants by Talaromyces/Penicillium: A review	56
Downstream processing technologies in the biocatalytic production of oligosaccharides	56
Understanding gradients in industrial bioreactors	56
Self-assembling peptide-based hydrogels: Fabrication, properties, and applications	56
Alternative sources and metabolic engineering of Taxol: Advances and future perspectives	55
Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics	53

How can ethanol enhance direct interspecies electron transfer in anaerobic digestion?	53
A navigation guide of synthetic biology tools for Pseudomonas putida	53
Bio-synthesis of food additives and colorants-a growing trend in future food	52
Amidase as a versatile tool in amide-bond cleavage: From molecular features to biotechnological applications	52
Mechanical properties of single cells: Measurement methods and applications	51
Smart microalgae farming with internet-of-things for sustainable agriculture	51
Engineering of Saccharomyces cerevisiae as a consolidated bioprocessing host to produce cellulosic ethanol: Recent advancements and current challenges	51
How does the Internet of Things (IoT) help in microalgae biorefinery?	50
Biotechnological production and high potential of furan-based renewable monomers and polymers	50
Review: Remotely controlled magneto-regulation of therapeutics from magnetoelastic gel matrices	50
On the verge of the market – Plant factories for the automated and standardized production of biopharmaceuticals	50
Can anaerobic digestion be a suitable end-of-life scenario for biodegradable plastics? A critical review of the current situation, hurdles, and challenges	49
Production of polyunsaturated fatty acids by Schizochytrium (Aurantiochytrium) spp.	48
Algal metabolites: An inevitable substitute for antibiotics	48
Biofilm control by interfering with c-di-GMP metabolism and signaling	48
Trends in the development of innovative nanobiocatalysts and their application in biocatalytic transformations	48
Next-generation metabolic engineering approaches towards development of plant cell suspension cultures as specialized metabolite producing biofactories	47
Recent advancements and challenges in emerging applications of biochar-based catalysts	47
Recent trends in methane to bioproduct conversion by methanotrophs	47
Unlocking the secret of lignin-enzyme interactions: Recent advances in developing state-of-the-art analytical techniques	46
Pathogens and predators impacting commercial production of microalgae and cyanobacteria	46
Extremophilic lipases for industrial applications: A general review	46
Ionic liquids for regulating biocatalytic process: Achievements and perspectives	46
Biocatalytic oxidation of fatty alcohols into aldehydes for the flavors and fragrances industry	45
What do we learn from enzyme behaviors in organic solvents? – Structural functionalization of ionic liquids for enzyme activation and stabilization	45
Hot spots-making directed evolution easier	45
Plant synthetic biology for producing potent phyto-antimicrobials to combat antimicrobial resistance	45
Biopolymers production from microalgae and cyanobacteria cultivated in wastewater: Recent advances	45
Refactoring transcription factors for metabolic engineering	44
Recent advances in lipid metabolic engineering of oleaginous yeasts	44
Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds	44
A review on the progress, challenges and prospects in commercializing microalgal fucoxanthin	44
From bumblebee to bioeconomy: Recent developments and perspectives for sophorolipid biosynthesis	43
Physical methods for controlling bacterial colonization on polymer surfaces	43
Microbial starch debranching enzymes: Developments and applications	42
Biotransformation of dietary phytoestrogens by gut microbes: A review on bidirectional interaction between phytoestrogen metabolism and gut microbiota	42
Waste-to-nutrition: a review of current and emerging conversion pathways	41
Engineer probiotic bifidobacteria for food and biomedical applications - Current status and future prospective	41
Chemical modification of enzymes to improve biocatalytic performance	41
Strategies for improving antimicrobial peptide production	41
Bacterial and enzymatic degradation of poly(cis-1,4-isoprene) rubber: Novel biotechnological applications	41
Genetic control of grain appearance quality in rice	40
Mycolicibacterium cell factory for the production of steroid-based drug intermediates	40
Cyanobacteria and microalgae in supporting human habitation on Mars	40
Engineering whole-cell microbial biosensors: Design principles and applications in monitoring and treatment of heavy metals and organic pollutants	40
Predicting drug-microbiome interactions with machine learning	40
Marine drugs: Biology, pipelines, current and future prospects for production	39
Insights on the emerging biotechnology of histidine-rich peptides	38
Electro-fermentation: Sustainable bioproductions steered by electricity	38
Harnessing cells to deliver nanoparticle drugs to treat cancer	38
Models of microalgal cultivation for added-value products - A review	38
Anodic electro-fermentation: Empowering anaerobic production processes via anodic respiration	38
Developing fungal heterologous expression platforms to explore and improve the production of natural products from fungal biodiversity	38
Current status and future prospects in cannabinoid production through in vitro culture and synthetic biology	37
Non-viral transfection technologies for next-generation therapeutic T cell engineering	37
Dehydrogenases of acetic acid bacteria	36
From lignocellulose to plastics: Knowledge transfer on the degradation approaches by fungi	36
Biotechnological applications of the non-conventional yeast Meyerozyma guilliermondii	36
Opportunities and challenges of the tag-assisted protein purification techniques: Applications in the pharmaceutical industry	36
Microbial-enabled green biosynthesis of nanomaterials: Current status and future prospects	36
Adaptive defensive mechanism of bioleaching microorganisms under extremely environmental acid stress: Advances and perspectives	35
The tale of a versatile enzyme: Molecular insights into keratinase for its industrial dissemination	35
Marine macroalgae in a circular economy context: A comprehensive analysis focused on residual biomass	35
Rhodopseudomonas palustris: A biotechnology chassis	35
Advances in enzymatic oxyfunctionalization of aliphatic compounds	35
Xylanases of glycoside hydrolase family 30 – An overview	35
Towards efficient enzymatic saccharification of pretreated lignocellulose: Enzyme inhibition by lignin-derived phenolics and recent trends in mitigation strategies	35
Agrobacterium strains and strain improvement: Present and outlook	34
Biopolymers and their derivatives: Key components of advanced biomedical technologies	34
Lactic acid bacteria-derived α-glucans: From enzymatic synthesis to miscellaneous applications	34
Phosphorylase-catalyzed bottom-up synthesis of short-chain soluble cello-oligosaccharides and property-tunable cellulosic materials	33
Type II methanotrophs: A promising microbial cell-factory platform for bioconversion of methane to chemicals	33
Data mining of Saccharomyces cerevisiae mutants engineered for increased tolerance towards inhibitors in lignocellulosic hydrolysates	33
Comparative analysis of the chemical and biochemical synthesis of keto acids	33
Noble metal nanoparticles in agriculture: impacts on plants, associated microorganisms, and biotechnological practices	33
Lipid metabolism research in oleaginous fungus Mortierella alpina: Current progress and future prospects	33
Bacterial membrane vesicle functions, laboratory methods, and applications	33
Biofilm application in the microbial biochemicals production process	33
Common problems associated with the microbial productions of aromatic compounds and corresponding metabolic engineering strategies	33
Synthetic biology-inspired strategies and tools for engineering of microbial natural product biosynthetic pathways	32

Microbial chassis engineering drives heterologous production of complex secondary metabolites	32
Cellulose- and xylan-degrading yeasts: Enzymes, applications and biotechnological potential	31
From fungal secretomes to enzymes cocktails: The path forward to bioeconomy	31
Exploitation of lignocellulosic-based biomass biorefinery: A critical review of renewable bioresource, sustainability and economic views	31
Engineering of primary carbon metabolism in filamentous fungi	31