Biotechnology Advances

Papers
(The median citation count of Biotechnology Advances is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-02-01 to 2024-02-01.)
ArticleCitations
A review of high value-added molecules production by microalgae in light of the classification255
Stabilization of enzymes via immobilization: Multipoint covalent attachment and other stabilization strategies253
Using machine learning approaches for multi-omics data analysis: A review249
Microalgae as a future food source249
Fungal potential for the degradation of petroleum-based polymers: An overview of macro- and microplastics biodegradation218
The approved gene therapy drugs worldwide: from 1998 to 2019204
The challenge and prospect of mRNA therapeutics landscape202
A critical review on exploiting the pharmaceutical potential of plant endophytic fungi195
Technologies for biological removal and recovery of nitrogen from wastewater185
Extracellular matrix-derived biomaterials in engineering cell function156
Evaluation of biological degradation of polyurethanes155
Enzyme co-immobilization: Always the biocatalyst designers' choice…or not?139
Bacterial cellulose micro-nano fibres for wound healing applications136
Paper-based point-of-care immunoassays: Recent advances and emerging trends133
RNA-based technologies for insect control in plant production128
Lignin nanoparticles enter the scene: A promising versatile green tool for multiple applications115
Molecular priming as an approach to induce tolerance against abiotic and oxidative stresses in crop plants113
Microbial extracellular electron transfer and strategies for engineering electroactive microorganisms113
Genetic engineering of microalgae for enhanced biorefinery capabilities112
Molecular farming – The slope of enlightenment111
Biotechnological potential and applications of microbial consortia107
Biotechnological production of astaxanthin from the microalga Haematococcus pluvialis105
Microbial electrosynthesis: Towards sustainable biorefineries for production of green chemicals from CO2 emissions105
Biopolymer-liposome hybrid systems for controlled delivery of bioactive compounds: Recent advances104
Microbial enzymes catalyzing keratin degradation: Classification, structure, function100
Purple phototrophic bacteria for resource recovery: Challenges and opportunities100
Consolidated bio-saccharification: Leading lignocellulose bioconversion into the real world96
Fermentation transforms the phenolic profiles and bioactivities of plant-based foods94
Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications94
Recent developments in the use of peroxygenases – Exploring their high potential in selective oxyfunctionalisations94
Mammalian cell culture for production of recombinant proteins: A review of the critical steps in their biomanufacturing93
Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts89
Biodegradation and up-cycling of polyurethanes: Progress, challenges, and prospects87
Algae biostimulants: A critical look at microalgal biostimulants for sustainable agricultural practices87
Potential of phytohormones as a strategy to improve microalgae productivity for biotechnological applications86
Strategies for improving the electroactivity and specific metabolic functionality of microorganisms for various microbial electrochemical technologies84
Microbial melanin: Recent advances in biosynthesis, extraction, characterization, and applications81
Prospects and development of algal-bacterial biotechnology in environmental management and protection79
Library preparation for next generation sequencing: A review of automation strategies77
Neural tissue engineering with structured hydrogels in CNS models and therapies76
Adaptive laboratory evolution principles and applications in industrial biotechnology75
Glycoside hydrolase family 18 chitinases: The known and the unknown75
Expanding the chemical diversity through microorganisms co-culture: Current status and outlook73
Lipase immobilization on ceramic supports: An overview on techniques and materials70
The invisible life inside plants: Deciphering the riddles of endophytic bacterial diversity70
Flavoprotein monooxygenases: Versatile biocatalysts69
Nanostructured antimicrobial peptides: The last push towards clinics69
Biological production of medium-chain carboxylates through chain elongation: An overview69
Biomaterializing the promise of cardiac tissue engineering66
Ecofriendly biopolymers and composites: Preparation and their applications in water-treatment65
The Yin and Yang of exosome isolation methods: conventional practice, microfluidics, and commercial kits65
Metabolic engineering of Saccharomyces cerevisiae for the production of top value chemicals from biorefinery carbohydrates65
Archaea Biotechnology64
Strategic enhancement of genetic gain for nutraceutical development in buckwheat: A genomics-driven perspective63
Consolidated bioprocessing of raw starch to ethanol by Saccharomyces cerevisiae: Achievements and challenges63
Vero cell upstream bioprocess development for the production of viral vectors and vaccines62
β-Galactosidases: A great tool for synthesizing galactose-containing carbohydrates61
Iron-assisted biological wastewater treatment: Synergistic effect between iron and microbes60
Current and novel approaches to downstream processing of microalgae: A review60
Anthocyanins, multi-functional natural products of industrial relevance: Recent biotechnological advances59
Developing Aspergillus niger as a cell factory for food enzyme production59
Molecularly imprinted polymers for the selective recognition of microorganisms59
Current trends in the production of biodegradable bioplastics: The case of polyhydroxyalkanoates58
Production of plant natural products through engineered Yarrowia lipolytica57
Soft and flexible material-based affinity sensors57
Antimicrobial properties and applications of metal nanoparticles biosynthesized by green methods56
Biodegradation of polyethylene and polystyrene: From microbial deterioration to enzyme discovery56
Bacterial cellulose and its potential for biomedical applications56
Biotechnological production of lipid and terpenoid from thraustochytrids55
Pseudomonas aeruginosa biofilms and their partners in crime54
Strategies to manipulate the performance of aptamers in SELEX, post-SELEX and microenvironment53
Combination of bioelectrochemical systems and electrochemical capacitors: Principles, analysis and opportunities53
Acetate as a potential feedstock for the production of value-added chemicals: Metabolism and applications53
Alternative sources and metabolic engineering of Taxol: Advances and future perspectives52
Microalgae with artificial intelligence: A digitalized perspective on genetics, systems and products52
In depth natural product discovery - Myxobacterial strains that provided multiple secondary metabolites52
Prospects on bio-based 2,3-butanediol and acetoin production: Recent progress and advances52
Biotechnological approaches for the production of natural colorants by Talaromyces/Penicillium: A review51
Downstream processing technologies in the biocatalytic production of oligosaccharides50
Biological and conventional food processing modifications on food proteins: Structure, functionality, and bioactivity50
Microbial production of limonene and its derivatives: Achievements and perspectives50
Inspired by nature: Microbial production, degradation and valorization of biodegradable bioplastics for life-cycle-engineered products49
Challenges in biodegradation of non-degradable thermoplastic waste: From environmental impact to operational readiness49
Whole-cell biocatalysis using cytochrome P450 monooxygenases for biotransformation of sustainable bioresources (fatty acids, fatty alkanes, and aromatic amino acids)49
Genetic engineering of microalgae for enhanced lipid production49
Whole-cell biocatalytic, enzymatic and green chemistry methods for the production of resveratrol and its derivatives49
Strategies employed in the design of antimicrobial peptides with enhanced proteolytic stability49
Flavonoids, terpenoids, and polyketide antibiotics: Role of glycosylation and biocatalytic tactics in engineering glycosylation48
Review of advances in the development of laccases for the valorization of lignin to enable the production of lignocellulosic biofuels and bioproducts48
Advances in the profiling of N6-methyladenosine (m6A) modifications47
Computational design of enzymes for biotechnological applications47
Sperm selection in assisted reproduction: A review of established methods and cutting-edge possibilities46
A navigation guide of synthetic biology tools for Pseudomonas putida46
Stress response in Rhodococcus strains45
A comprehensive and critical review on key elements to implement enzymatic PET depolymerization for recycling purposes45
Self-assembling peptide-based hydrogels: Fabrication, properties, and applications44
Trends in the development of innovative nanobiocatalysts and their application in biocatalytic transformations44
Bio-synthesis of food additives and colorants-a growing trend in future food43
Mechanical properties of single cells: Measurement methods and applications43
Smart microalgae farming with internet-of-things for sustainable agriculture43
How can ethanol enhance direct interspecies electron transfer in anaerobic digestion?43
Understanding gradients in industrial bioreactors43
Review: Remotely controlled magneto-regulation of therapeutics from magnetoelastic gel matrices43
Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics42
Engineering of Saccharomyces cerevisiae as a consolidated bioprocessing host to produce cellulosic ethanol: Recent advancements and current challenges42
Boosting extracellular vesicle secretion40
Algal metabolites: An inevitable substitute for antibiotics40
Production of polyunsaturated fatty acids by Schizochytrium (Aurantiochytrium) spp.40
How does the Internet of Things (IoT) help in microalgae biorefinery?40
Next-generation metabolic engineering approaches towards development of plant cell suspension cultures as specialized metabolite producing biofactories40
Engineering unnatural methylotrophic cell factories for methanol-based biomanufacturing: Challenges and opportunities40
Towards manufacturing of human organoids40
Physical methods for controlling bacterial colonization on polymer surfaces39
Ionic liquids for regulating biocatalytic process: Achievements and perspectives39
Biotechnological production and high potential of furan-based renewable monomers and polymers39
Unlocking the secret of lignin-enzyme interactions: Recent advances in developing state-of-the-art analytical techniques38
Plant synthetic biology for producing potent phyto-antimicrobials to combat antimicrobial resistance38
On the verge of the market – Plant factories for the automated and standardized production of biopharmaceuticals38
Harnessing cells to deliver nanoparticle drugs to treat cancer37
Amidase as a versatile tool in amide-bond cleavage: From molecular features to biotechnological applications37
Recent advances in lipid metabolic engineering of oleaginous yeasts37
Biopolymers production from microalgae and cyanobacteria cultivated in wastewater: Recent advances37
Recent trends in methane to bioproduct conversion by methanotrophs37
Microbial starch debranching enzymes: Developments and applications36
Expansion of human mesenchymal stem/stromal cells (hMSCs) in bioreactors using microcarriers: lessons learnt and what the future holds36
Biocatalytic oxidation of fatty alcohols into aldehydes for the flavors and fragrances industry36
From bumblebee to bioeconomy: Recent developments and perspectives for sophorolipid biosynthesis36
A review on the progress, challenges and prospects in commercializing microalgal fucoxanthin36
Microbial production of vitamin K2: current status and future prospects36
Engineer probiotic bifidobacteria for food and biomedical applications - Current status and future prospective35
Models of microalgal cultivation for added-value products - A review35
Biotransformation of dietary phytoestrogens by gut microbes: A review on bidirectional interaction between phytoestrogen metabolism and gut microbiota35
Can anaerobic digestion be a suitable end-of-life scenario for biodegradable plastics? A critical review of the current situation, hurdles, and challenges35
Developing fungal heterologous expression platforms to explore and improve the production of natural products from fungal biodiversity35
Predicting drug-microbiome interactions with machine learning35
What do we learn from enzyme behaviors in organic solvents? – Structural functionalization of ionic liquids for enzyme activation and stabilization35
Current status and future prospects in cannabinoid production through in vitro culture and synthetic biology34
Marine drugs: Biology, pipelines, current and future prospects for production34
Mycolicibacterium cell factory for the production of steroid-based drug intermediates34
Current advances in microsphere based cell culture and tissue engineering33
Bacterial and enzymatic degradation of poly(cis-1,4-isoprene) rubber: Novel biotechnological applications33
Pathogens and predators impacting commercial production of microalgae and cyanobacteria33
Anodic electro-fermentation: Empowering anaerobic production processes via anodic respiration33
From lignocellulose to plastics: Knowledge transfer on the degradation approaches by fungi32
Electro-fermentation: Sustainable bioproductions steered by electricity32
Extremophilic lipases for industrial applications: A general review32
Waste-to-nutrition: a review of current and emerging conversion pathways32
Non-viral transfection technologies for next-generation therapeutic T cell engineering31
Biofilm control by interfering with c-di-GMP metabolism and signaling31
Advances in enzymatic oxyfunctionalization of aliphatic compounds31
Biotechnological applications of the non-conventional yeast Meyerozyma guilliermondii31
Insights on the emerging biotechnology of histidine-rich peptides31
Marine macroalgae in a circular economy context: A comprehensive analysis focused on residual biomass30
Common problems associated with the microbial productions of aromatic compounds and corresponding metabolic engineering strategies30
Refactoring transcription factors for metabolic engineering30
Hot spots-making directed evolution easier30
Chemical modification of enzymes to improve biocatalytic performance30
Harmonization of immunoassays for biomarkers in diabetes mellitus29
Adaptive defensive mechanism of bioleaching microorganisms under extremely environmental acid stress: Advances and perspectives29
Controlling biofilms using synthetic biology approaches29
Engineering whole-cell microbial biosensors: Design principles and applications in monitoring and treatment of heavy metals and organic pollutants29
Phosphorylase-catalyzed bottom-up synthesis of short-chain soluble cello-oligosaccharides and property-tunable cellulosic materials29
Biofilm application in the microbial biochemicals production process29
From fungal secretomes to enzymes cocktails: The path forward to bioeconomy29
Xylanases of glycoside hydrolase family 30 – An overview29
Heterologous expression of lytic polysaccharide monooxygenases (LPMOs)29
Lipid metabolism research in oleaginous fungus Mortierella alpina: Current progress and future prospects29
Microbial chassis engineering drives heterologous production of complex secondary metabolites28
Engineering of primary carbon metabolism in filamentous fungi28
Engineering salt tolerance of photosynthetic cyanobacteria for seawater utilization28
Cellular engineering strategies toward sustainable omega-3 long chain polyunsaturated fatty acids production: State of the art and perspectives28
Synthetic biology-inspired strategies and tools for engineering of microbial natural product biosynthetic pathways28
Comparative analysis of the chemical and biochemical synthesis of keto acids28
Genetic control of grain appearance quality in rice28
Towards Green Nanoscience: From extraction to nanoformulation28
Cyanobacteria and microalgae in supporting human habitation on Mars27
Dehydrogenases of acetic acid bacteria27
Strategies for improving antimicrobial peptide production27
Sowing seeds for the future: The need for on-site plant diagnostics27
Protein folding and assembly in confined environments: Implications for protein aggregation in hydrogels and tissues27
Microbial-enabled green biosynthesis of nanomaterials: Current status and future prospects27
Lactic acid bacteria-derived α-glucans: From enzymatic synthesis to miscellaneous applications27
Noble metal nanoparticles in agriculture: impacts on plants, associated microorganisms, and biotechnological practices27
Cyanobacterial sigma factors: Current and future applications for biotechnological advances27
The tale of a versatile enzyme: Molecular insights into keratinase for its industrial dissemination26
Towards a new avenue for producing therapeutic proteins: Microalgae as a tempting green biofactory26
Towards efficient enzymatic saccharification of pretreated lignocellulose: Enzyme inhibition by lignin-derived phenolics and recent trends in mitigation strategies26
Opportunities and challenges of the tag-assisted protein purification techniques: Applications in the pharmaceutical industry26
Agrobacterium strains and strain improvement: Present and outlook26
Surrogate broodstock to enhance biotechnology research and applications in aquaculture26
Bionanomaterials based on protein self-assembly: Design and applications in biotechnology25
Bacterial membrane vesicle functions, laboratory methods, and applications25
Gum polysaccharide/nanometal hybrid biocomposites in cancer diagnosis and therapy25
An overview and future prospects of sialic acids25
Rhodopseudomonas palustris: A biotechnology chassis25
Advanced glycosidases as ingenious biosynthetic instruments24
Data mining of Saccharomyces cerevisiae mutants engineered for increased tolerance towards inhibitors in lignocellulosic hydrolysates24
Cellulose- and xylan-degrading yeasts: Enzymes, applications and biotechnological potential24
Synthetic protein scaffolds for the colocalisation of co-acting enzymes24
Type II methanotrophs: A promising microbial cell-factory platform for bioconversion of methane to chemicals24
Recent advances in fed-batch microscale bioreactor design24
Agarose degradation for utilization: Enzymes, pathways, metabolic engineering methods and products23
Photocatalyst-enzyme hybrid systems for light-driven biotransformation23
Recent advances in human respiratory epithelium models for drug discovery23
Progress in biohythane production from microalgae-wastewater sludge co-digestion: An integrated biorefinery approach22
Bacterial sialyltransferases and their use in biocatalytic cascades for sialo-oligosaccharide production22
Microbial inhibition and biosensing with multifunctional carbon dots: Progress and perspectives22
Medicinal plants used in the treatment of tuberculosis - Ethnobotanical and ethnopharmacological approaches22
Adaptive innovation of green plants by horizontal gene transfer22
The evolving art of creating genetic diversity: From directed evolution to synthetic biology22
Bacterial membrane transporter systems for aromatic compounds: Regulation, engineering, and biotechnological applications21
The vast repertoire of carbohydrate oxidases: An overview21
Advances in synthetic biology tools paving the way for the biomanufacturing of unusual fatty acids using the Yarrowia lipolytica chassis21
Cellular pathways of recombinant adeno-associated virus production for gene therapy21
Immobilized fungal enzymes: Innovations and potential applications in biodegradation and biosynthesis21
Recent advances in biocatalysis of nitrogen-containing heterocycles20
Genetic toolkits for engineering Rhodococcus species with versatile applications20
Bacterial protein acetylation and its role in cellular physiology and metabolic regulation20
The biomedical and bioengineering potential of protein nanocompartments20
Bioprospecting for bioactive compounds in microalgae: Antimicrobial compounds20
Recent advancements and challenges in emerging applications of biochar-based catalysts20
Bacterial biofilms as platforms engineered for diverse applications20
Mimicking natural strategies to create multi-environment enzymatic reactors: From natural cell compartments to artificial polyelectrolyte reactors20
CRISPR-based enrichment strategies for targeted sequencing20
Advances in engineering UDP-sugar supply for recombinant biosynthesis of glycosides in microbes20
Recent advances in enzyme-enhanced immunosensors20
Insights to improve the plant nutrient transport by CRISPR/Cas system20
Computer-aided understanding and engineering of enzymatic selectivity20
Biopolymers and their derivatives: Key components of advanced biomedical technologies19
Plant-made immunotoxin building blocks: A roadmap for producing therapeutic antibody-toxin fusions19
Recent advances in tuning the expression and regulation of genes for constructing microbial cell factories19
Heterologous production of cellulose- and starch-degrading hydrolases to expand Saccharomyces cerevisiae substrate utilization: Lessons learnt19
4D printing: Perspectives for the production of sustainable plastics for agriculture19
Kluyveromyces marxianus as a microbial cell factory for lignocellulosic biomass valorisation19
The bacterial phylum Planctomycetes as novel source for bioactive small molecules19
Chromosome genomics uncovers plant genome organization and function19
Nanoantibiotics to fight multidrug resistant infections by Gram-positive bacteria: hope or reality?19
Exploration of space to achieve scientific breakthroughs19
Insect odorant receptor-based biosensors: Current status and prospects18
New trends in biotechnological applications of photosynthetic microorganisms18
Metabolic engineering of microbes for monoterpenoid production18
Improving microalgae for biotechnology — From genetics to synthetic biology – Moving forward but not there yet18
Bacillus licheniformis: The unexplored alternative for the anaerobic production of lipopeptide biosurfactants?18
Resveratrol and cyclodextrins, an easy alliance: Applications in nanomedicine, green chemistry and biotechnology18
Factors affecting the quality of therapeutic proteins in recombinant Chinese hamster ovary cell culture18
Plants arabinogalactans: From structures to physico-chemical and biological properties17
Halocins, natural antimicrobials of Archaea: Exotic or special or both?17
Application of microbial 3-ketosteroid Δ1-dehydrogenases in biotechnology17
Genome edited wheat- current advances for the second green revolution17
Engineering Staphylococcal Protein A for high-throughput affinity purification of monoclonal antibodies17
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