OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology Advances is 64. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Editorial Board	274
Editorial Board	200
Methanol metabolism in synthetic methylotrophic microorganisms	176
Targeted analysis of metagenomes: divide and conquer	157
New perspectives into Gluconobacter-catalysed biotransformations	156
Microbial cell surface engineering for high-level synthesis of bio-products	151
Collagen processing with mesoscale aggregates as templates and building blocks	151
Advancements of astaxanthin production in Haematococcus pluvialis: Update insight and way forward	133
Development of isopentenyl phosphate kinases and their application in terpenoid biosynthesis	133
Biotechnological production and emerging applications of betalains: A review	132
Evolving perspectives on lutein production from microalgae - A focus on productivity and heterotrophic culture	131
Decoding microbial interactions: Interaction networks and regulatory strategies for medium-chain fatty acid biosynthesis through anaerobic chain elongation	131
Recent advances in human respiratory epithelium models for drug discovery	117
Computer-aided understanding and engineering of enzymatic selectivity	115
Anaerobic digestion integrated with microbial electrolysis cell to enhance biogas production and upgrading in situ	114
Use of additives to improve collective biogas plant performances: A comprehensive review	113
Accessing hidden microbial biosynthetic potential from underexplored sources for novel drug discovery	108
Benzylisoquinoline alkaloid production: Moving from crop farming to chemical and biosynthesis	107
Recent advances and perspectives on production of value-added organic acids through metabolic engineering	103
Think outside the box: 3D bioprinting concepts for biotechnological applications – recent developments and future perspectives	102
Potential for microbial plastic degradation via assimilation of non-carbon moieties in additives	101
Opportunities for visual techniques to determine characteristics and limitations of electro-active biofilms	99
Phosphorylated polysaccharides: Applications, natural abundance, and new-to-nature structures generated by chemical and enzymatic functionalisation	97
Biosensors in microalgae: A roadmap for new opportunities in synthetic biology and biotechnology	96
Pickering emulsion biocatalysis: Bridging interfacial design with enzymatic reactions	95

Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications	93
Chiral helical scaffolds: Unlocking their potential in biomolecular interactions and biomedical applications	93
The path to biotechnological singularity: Current breakthroughs and outlook	92
Editorial Board	92
Editorial Board	92
Emerging research insights and future perspectives on the advancement of eccDNA: A comprehensive review	90
Biotechnological applications of purine and pyrimidine deaminases	88
Charting the landscape of RNA polymerases to unleash their potential in strain improvement	86
Polyethylene biodegradation: A multifaceted approach	86
Plant cell wall biosynthesis: Immune signaling, genome editing, and physiological implications for biomass valorization	84
Enzymatic de novo oligonucleotide synthesis: Emerging techniques and advancements	83
Methanotrophs as a reservoir for bioactive secondary metabolites: Pitfalls, insights and promises	83
Advances in gene editing-led route for hybrid breeding in crops	81
Haloferax and the Haloferacaceae: Potential role in bioindustry	81
Alpha-ketoacid decarboxylases: Diversity, structures, reaction mechanisms, and applications for biomanufacturing of platform chemicals and fuels	81
Growth-coupled high throughput selection for directed enzyme evolution	81
Protease engineering: Approaches, tools, and emerging trends	80
Biological valorization of lignin to flavonoids	79
Recent advances in machine learning applications in metabolic engineering	76
Genome-scale metabolic network models for industrial microorganisms metabolic engineering: Current advances and future prospects	76
Unlocking the secret of lignin-enzyme interactions: Recent advances in developing state-of-the-art analytical techniques	76
Electrode functional microorganisms in bioelectrochemical systems and its regulation: A review	75
Elucidation and biosynthesis of tetrahydroisoquinoline alkaloids: Recent advances and prospects	75
Ex-situ biomethanation for CO2 valorization: State of the art, recent advances, challenges, and future prospective	73
Biocatalytic oxyfunctionalization of unsaturated fatty acids to oxygenated chemicals via hydroxy fatty acids	72
Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics	71
Advances in bacterial glycoprotein engineering: A critical review of current technologies, emerging challenges, and future directions	71
Recent advances in research for potential utilization of unexplored lichen metabolites	70
Rutinosidase and other diglycosidases: Rising stars in biotechnology	70
Guidelines toward ecologically-informed bioprospecting for microbial plastic degradation	70
Resource allocation in mammalian systems	70
Emerging advances in glycoengineering of carbohydrates/glycans and their industrial applications	70
Bioinspired nanoplatforms for human-machine interfaces: Recent progress in materials and device applications	67
Loop engineering in enzymes from structure to function: Mechanisms, methodologies, and engineering strategies	66
Problems and corresponding strategies for converting CO2 into value-added products in Cupriavidus necator H16 cell factories	65
Engineering oleaginous red yeasts as versatile chassis for the production of oleochemicals and valuable compounds: Current advances and perspectives	65
Research progress of engineering microbial cell factories for pigment production	65
Unlocking the bacterial domain for industrial biotechnology applications using universal parts and tools	65
Improving recombinant protein production in CHO cells using the CRISPR-Cas system	64
Strategies for overcoming the limitations of enzymatic carbon dioxide reduction	64