OOIR: Observatory of International Research

Papers

(The H4-Index of Biotechnology Advances is 66. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Editorial Board	321
Editorial Board	183
Use of additives to improve collective biogas plant performances: A comprehensive review	171
Targeted analysis of metagenomes: divide and conquer	166
Collagen processing with mesoscale aggregates as templates and building blocks	161
Biotechnological production and emerging applications of betalains: A review	157
Advancements of astaxanthin production in Haematococcus pluvialis: Update insight and way forward	154
Decoding microbial interactions: Interaction networks and regulatory strategies for medium-chain fatty acid biosynthesis through anaerobic chain elongation	140
Development of isopentenyl phosphate kinases and their application in terpenoid biosynthesis	134
Biotechnological advances in key regulatory genes of phenylpropanoid and terpenoid biosynthesis pathways in Panax ginseng: Current insights and future prospects	130
Evolving perspectives on lutein production from microalgae - A focus on productivity and heterotrophic culture	128
Anaerobic digestion integrated with microbial electrolysis cell to enhance biogas production and upgrading in situ	123
New perspectives into Gluconobacter-catalysed biotransformations	118
Biosensors in microalgae: A roadmap for new opportunities in synthetic biology and biotechnology	118
Machine learning methods for small data and upstream bioprocessing applications: A comprehensive review	118
Methanol metabolism in synthetic methylotrophic microorganisms	118
Benzylisoquinoline alkaloid production: Moving from crop farming to chemical and biosynthesis	114
Opportunities for visual techniques to determine characteristics and limitations of electro-active biofilms	113
Accessing hidden microbial biosynthetic potential from underexplored sources for novel drug discovery	113
Pickering emulsion biocatalysis: Bridging interfacial design with enzymatic reactions	111
Potential for microbial plastic degradation via assimilation of non-carbon moieties in additives	107
Microbial computing: Review and Perspectives	103
Glycosylation in extracellular vesicles: Isolation, characterization, composition, analysis and clinical applications	103
Chiral helical scaffolds: Unlocking their potential in biomolecular interactions and biomedical applications	102
Phosphorylated polysaccharides: Applications, natural abundance, and new-to-nature structures generated by chemical and enzymatic functionalisation	100

Recent advances and perspectives on production of value-added organic acids through metabolic engineering	100
Think outside the box: 3D bioprinting concepts for biotechnological applications – recent developments and future perspectives	96
Editorial Board	96
Biological valorization of lignin to flavonoids	92
Plant cell wall biosynthesis: Immune signaling, genome editing, and physiological implications for biomass valorization	90
The path to biotechnological singularity: Current breakthroughs and outlook	90
Electrode functional microorganisms in bioelectrochemical systems and its regulation: A review	89
Genome-scale metabolic network models for industrial microorganisms metabolic engineering: Current advances and future prospects	86
Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics	85
Ex-situ biomethanation for CO2 valorization: State of the art, recent advances, challenges, and future prospective	84
Droplet microfluidics for single-cell analysis: From improved cell encapsulation and sorting technologies to innovative applications	82
Advances in gene editing-led route for hybrid breeding in crops	82
Methanotrophs as a reservoir for bioactive secondary metabolites: Pitfalls, insights and promises	81
Emerging research insights and future perspectives on the advancement of eccDNA: A comprehensive review	81
Biotechnological applications of purine and pyrimidine deaminases	78
Alpha-ketoacid decarboxylases: Diversity, structures, reaction mechanisms, and applications for biomanufacturing of platform chemicals and fuels	77
Advances and challenges in enzymatic rubber degradation: Exploring genetic, molecular, and biotechnological aspects	77
Haloferax and the Haloferacaceae: Potential role in bioindustry	76
Advances in transcription factor-based biosensors for natural product biosynthesis: Optimization, emerging technologies, and future prospects	76
Recent advances in machine learning applications in metabolic engineering	76
Enzymatic de novo oligonucleotide synthesis: Emerging techniques and advancements	75
Computational methods for spatial multi-omics integration	75
Elucidation and biosynthesis of tetrahydroisoquinoline alkaloids: Recent advances and prospects	75
Protease engineering: Approaches, tools, and emerging trends	74
Polyethylene biodegradation: A multifaceted approach	74
Growth-coupled high throughput selection for directed enzyme evolution	74
Biocatalytic oxyfunctionalization of unsaturated fatty acids to oxygenated chemicals via hydroxy fatty acids	74
Bioinspired nanoplatforms for human-machine interfaces: Recent progress in materials and device applications	73
Strategies for overcoming the limitations of enzymatic carbon dioxide reduction	72
Editorial Board	71
Unlocking the bacterial domain for industrial biotechnology applications using universal parts and tools	71
Emerging advances in glycoengineering of carbohydrates/glycans and their industrial applications	71
Advances in in vitro cultivation techniques for comprehensive analysis of human gut microbiome	70
Expanding sugar alcohol industry: Microbial production of sugar alcohols and associated chemocatalytic derivatives	70
Influence of elevated pressure and pressurized fluids on microenvironment and activity of enzymes	69
Utilization of gene manipulation system for advancing the biotechnological potential of halophiles: A review	69
The fungal cure: Harnessing mycelial approach as sustainable green solution for industrial waste treatment	68
Recent advances in research for potential utilization of unexplored lichen metabolites	67
Optimizing prime editing: Advances in efficiency enhancement	67
Advances in bacterial glycoprotein engineering: A critical review of current technologies, emerging challenges, and future directions	67
Resource allocation in mammalian systems	66