Journal of Pharmaceutical and Biomedical Analysis

Papers
(The TQCC of Journal of Pharmaceutical and Biomedical Analysis is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Chiral high-performance liquid chromatography analysis of mono-, di-, and triacylglycerols with amylose- and cellulose-phenylcarbamate-based stationary phases227
Development of bioassay platforms for biopharmaceuticals using Jurkat-CAR cells by AICD80
Unraveling the cytotoxicity and cellular uptake of low, medium and high molecular weight polyethylene glycol polymers in MCF-7 cells by green UPLC-MS/MS methods80
Indicator displacement-based colorimetric assay for dibutyl phthalate in pharmaceutical products with titanium(IV)-pyridylazo resorcinol (PAR)75
Extrahepatic in vitro metabolism of peptides; comparison of human kidney and intestinal S9 fraction, human plasma and proximal tubule cells, using cyclosporine A, leuprorelin, and cetrorelix as model 65
Identifying potential ligands specifically binding to beta1-adrenoceptor from Radix Aconiti Lateralis Praeparata extract by affinity chromatographic method61
Emerging analytical techniques for pharmaceutical quality control: Where are we in 2022?56
The first RP-UHPLC method for simultaneous quantification of abiraterone acetate, its four degradants, and six specified process impurities and correct identification of all analytes based on molecula53
Hepatic in vitro metabolism of peptides; Comparison of human liver S9, hepatocytes and Upcyte hepatocytes with cyclosporine A, leuprorelin, desmopressin and cetrorelix as model compounds52
LC-MS/MS studies for identification and characterization of new forced degradation products of dabrafenib and establishment of their degradation pathway44
Development of a highly sensitive method for the quantitative analysis of modified nucleosides using UHPLC-UniSpray-MS/MS44
LC and LC–MS/MS studies for identification and characterization of new degradation products of ibrutinib and elucidation of their degradation pathway43
Synthesis and standardization of an impurity of acetaminophen, development and validation of liquid chromatographic method42
Simultaneous determination of praziquantel, fipronil, eprinomectin, (S)-methoprene, their key related substances and butylated hydroxytoluene (BHT) in a topical veterinary drug product by a single sta41
The POWER saga from 2007 to 2022: An example of a sexual enhancement dietary supplement tainted by different adulterants and still on the market40
Identification of ADB-5’Br-BINACA in plant material and analytical characterization using GC-MS, LC-QTOF-MS, NMR and ATR-FTIR39
Efficacy evaluation and metabolomics analysis of raw and salt-processed Achyranthes bidentata Radix in zebrafish larvae for osteoporosis treatment38
Transcriptomics and UHPLC-QQQ-MS analyses reveal the dysregulation of branched chain amino acids metabolism in renal fibrotic rats35
Development and validation of a sensitive LC-MS/MS assay of GT-14, a novel Gαi2 inhibitor, in rat plasma, and its application in pharmacokinetic study35
Comprehensive evaluation of the mechanism of Banxia Baizhu Tianma Decoction in ameliorating posterior circulation ischemia vertigo based on integrating fecal short-chain fatty acids and 16S rRNA seque34
Exploring the gut microbiota mediated biotransformation of Senecio scandens Buch.-Ham.: Insights from metabolite spectrum with UHPLC-Q-Orbitrap HRMS and bioinformatics analysis of gut microbiota metab33
Exploring the composition and properties of Centella asiatica metabolites and investigating their impact on BSA glycation, LDL oxidation and α-amylase inhibition33
Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis32
Amanitin determination in bile samples by UHPLC-MS: LR-MS and HR-MS analytical performance32
Comparison of whole-blood sirolimus concentrations measured by EMIT-based Siemens Viva-ProE® System and LC-MS/MS in Chinese transplant patients31
Quantitation of total antibody (tAb) from antibody drug conjugate (ADC) PYX-201 in rat and monkey plasma using an enzyme-linked immunosorbent assay (ELISA) and its application in preclinical studies31
A study on cholesterol-cholesteryl ester metabolic homeostasis and drug intervention in hyperlipidemic hamsters using UHPLC-MS/MS31
Determination of related substances in egg yolk lecithin by HPLC-CAD and characterization of its profiling by HPLC-Q-TOF-MS30
One-pot synthesis of β-cyclodextrin modified silver nanoparticles for highly sensitive detection of ciprofloxacin30
N-glycosylation structure – function characterization of omalizumab, an anti-asthma biotherapeutic product29
Altered amino acid metabolism between coronary heart disease patients with and without type 2 diabetes by quantitative 1H NMR based metabolomics29
Anti-heart failure mechanism of saponin extract of black ginseng based on metabolomics28
A fit-for-purpose LC-MS/MS method for the analysis of selected Streptococcal quorum sensing peptides in human saliva28
Influence of drying process on furostanoside and spirostanoside profiles of Paridis Rhizoma by combination of HPLC, UPLC and UPLC-QTOF-MS/MS analyses28
Antioxidant compounds of Kielmeyera coriacea Mart. with α-amylase, lipase and advanced glycation end-product inhibitory activities28
In vitro characterization of S-23 metabolites produced by human liver microsomes, and subsequent application to urine after a controlled oral administration28
Metabolism of dipentylone in zebrafish and human liver microsomes determined by liquid chromatography–high resolution mass spectrometry27
Small volume rapid equilibrium dialysis (RED) measures effects of interstitial parameters on the protein-bound fraction of topical drugs27
Analytical approaches to assess metabolic changes in psoriasis27
Determination of fluoroquinolones in dried plasma spots by using microwave-assisted extraction coupled to ultra-high performance liquid chromatography-tandem mass spectrometry for therapeutic drug mon26
Metabolic characteristic profiling of 1-amino-3,3-dimethyl-1-oxobutan-2-yl-derived indole and indazole synthetic cannabinoids in vitro26
Development and evaluation of a new test kit for determination of immunosuppressants in blood by UHPLC-MS/MS26
Systematic investigation of the pharmacological mechanism of Tanreqing injection in treating respiratory diseases by UHPLC/Q-TOF-MS/MS based on multiple in-house chemical libraries coupled with networ26
Quality evaluation of Qiangli Tianma Duzhong (QLTMDZ) employing UHPLC-MS: A multivariate statistical analysis across multiple dosage forms and manufacturers26
Optimization of pretreatment methods for cerebrospinal fluid metabolomics based on ultrahigh performance liquid chromatography/mass spectrometry25
The nitrosamine contamination of drugs, part 3: Quantification of 4-Methyl-1-nitrosopiperazine in rifampicin capsules by LC-MS/HRMS25
Characterization and comparison of polysaccharides from Achyranthes bidentata, Cyathula officinalis and Achyranthes aspera by saccharides mapping25
Susceptibility of cosmeceutical peptides to proteases activity: Development of dermal stability test by LC-MS/MS analysis25
Integrated UHPLC-MS untargeted metabolomics and gut microbe metabolism pathway-targeted metabolomics to reveal the prevention mechanism of Gushudan on kidney-yang-deficiency-syndrome rats25
Detection of antibody-conjugate payload in cynomolgus monkey serum by a high throughput capture LC–MS/MS bioanalysis method25
Matrix-assisted laser desorption/ionization mass spectrometric imaging the spatial distribution of biodegradable vascular stents using a self-made semi-quantitative target plate25
Development and validation of bioanalytical assays for the quantification of 9MW2821, a nectin-4-targeting antibody–drug conjugate25
Development and validation of an HPLC-MS/MS method for the quantification of the anti-leishmanial drug miltefosine in human skin tissue25
Simultaneous determination of 13 nitrosamine impurities in biological medicines using salting-out liquid-liquid extraction coupled with liquid chromatography tandem mass spectrometry25
HILIC-UV determination of lysine and chloride counterions in active pharmaceutical ingredients25
Editorial Board25
Kinetic and mechanism study of the spontaneous, solvent- and base-catalyzed degradation of the precursor of the β-nitro alcohol metaraminol by combining HPLC/electronic circular dichroism/theoretical 24
Qualitative and quantitative evaluations of Chuanxiong dispensing granules by using chemical fingerprint in combination with chemometrics methods24
Tackling quantitative polymorphic analysis through fixed-dose combination tablets production. Pyrazinamide polymorphic assessment24
Single-type reporter multiplexing with A single droplet through bead-based digital microfluidics24
Quantitative measurements of IR780 in formulations and tissues24
Multinuclear NMR screening of pharmaceuticals using standardization by 2H integral of a deuterated solvent24
A validated UHPLC-MS/MS method for quantification of total and free tedizolid concentrations in human plasma24
Enabling direct and definitive free fraction determination for highly-bound compounds in protein binding assay24
Chemical profiles, differentiation, and quality evaluation of Radix et Rhizoma Thalictri Foliolosi based on LC-MS24
l-Asparaginase and HCP quantification by SWATH LC-MS/MS for new and improved purification step in Erwinia chrysanthemi l-asparaginase manufacture23
New stochastic devices for simultaneous analysis of mismatch repair proteins and KRAS in biological samples23
Updating the European Pharmacopoeia impurity profiling method for cetirizine and suggesting alternative column, using design space comparison23
Quantitative Quadrupolar NMR (qQNMR) via nitrogen-14 for the accurate control of L-carnitine in food supplements23
A ratiometric electrochemical biosensor via alkaline phosphatase mediated dissolution of nano-MnO2 and Ru(III) redox recycling for the determination of dimethoate23
Mass spectrum oriented metabolomics for evaluating the efficacy and discovering the metabolic mechanism of Naoling Pian for insomnia23
Insight into the degradation of amino substituted benzimidazo[1,2-a]quinolines via a combined experimental and density functional theory study23
Development and validation of an LC-MS/MS assay for the quantification of cintirorgon (LYC-55716) in mouse plasma and tissue homogenates23
2-μm fused-core column ultra-high-performance liquid chromatography/tandem mass spectrometric determination of donepezil in human plasma: Application to a bioequivalence study22
Quantitative study of ternary polycrystalline mixtures of prulifloxacin based on Raman spectra and Raman imaging maps22
Correlation analysis of physicochemical properties with anti-inflammatory activity of Andrographis paniculata (Burm.f.) Nees based on HPLC-DAD, colorimeter and multivariate statistics: A comprehensive22
Development, methodological evaluation and application of a cell-based TRF assay for analysis of ADCC activity22
Mariani wine: What's really in it? Analysis of the most popular tonic drink of the 19th century after 100 years of storage22
NMR-based metabolomics of dried berries in comparison with dietary supplements21
Comparative analysis of chemical components in fruits of Chebulae Fructus and its pulp based on chromatographic technology coupled with multivariate chemometric methods21
Ultra Performance Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry (UPLC-Q-TOF-MS)-based metabolomic analysis of mycelial biomass of three Ganoderma isolates from the Lower Volta Rive21
Experimental design of a stable isotope labeling derivatized UHPLC–MS/MS method for the detection/quantification of primary/secondary bile acids in biofluids21
Development of organic three-phase laminar flow microfluidic chip for extraction of ginsenosides from Panax ginseng21
Urinary metabolomics analysis to reveal metabolic mechanism of guanxinning injection on heart failure with renal dysfunction21
Serum and urine metabolomics study revealed the amelioration of Gynura bicolor extract on high fat diet-fed and streptozotocin-induced type 2 diabetic mice based on UHPLC-MS/MS21
An UPLC-MS/MS method for targeted analysis of microbial and host tryptophan metabolism after administration of polysaccharides from Atractylodes macrocephala Koidz. in ulcerative colitis mice21
Green, rapid and simultaneous determination of ‘alternative preservatives’ in cosmetic formulations by gas chromatography-mass spectrometry21
Disposable nanosensor for the electrochemical determination of the interaction between DNA, and a mycotoxin, patulin21
Separation and quantification of Azvudine in plasma of patients with COVID-19 using LC-MS/MS21
UHPLC-HRMS-based serum untargeted lipidomics: Phosphatidylcholines and sphingomyelins are the main disturbed lipid markers to distinguish colorectal advanced adenoma from cancer21
Detection and differentiation of active and inactive isoforms of coagulation factors II, VII, IX, and X in prothrombin complex concentrate by mass spectrometry21
Qualitative and quantitative analysis of the component variations of Raphani Semen during the stir-frying process and elucidation of transformation pathways of multiple components21
Screening and identification of Euphorbiae pekinensis Rupr. anti-angiogenic multi-components with UPLC-QTOF-MS in zebrafish20
A comprehensive strategy for the identification of biologics by liquid-chromatography–mass spectrometry for release testing in a regulated environment20
Development and application of immunoassays for rapid quality control of the antimalarial drug combination artesunate-mefloquine20
Comparative LC-MS/MS-based molecular networking, DNA fingerprinting, and in vitro anti-Helicobacter pylori activity of three Egyptian Ficus cultivars20
Hair-based rapid UPLC-MS/MS analysis of 36 phencyclidine-type substances in forensic cases20
Challenges in sample preparation for swellable core technology tablets: Approaches for the removal of polyethylene oxide and optimization of API recovery20
Electrochemistry/mass spectrometry (EC/MS) for fast generation and identification of novel reactive metabolites of two unsymmetrical bisacridines with anticancer activity20
A preclinical study on online monitoring of exhaled ciprofol concentration by the ultraviolet time-of-flight spectrometer and prediction of anesthesia depth in beagles20
Characterization of the metabolite of cabozantinib generated from liver microsomes and hepatocytes by ultra-high performance liquid chromatography coupled to quadrupole/orbitrap high resolution mass s20
Editorial Board20
LC-MS/MS based metabolomic analysis of serum from patients with cerebrovascular stenosis20
Development and validation of LC-MS/MS methods for the quantification of 101BHG-D01, a novel, long-acting and selective muscarinic receptor antagonist, and its main metabolite M6 in human plasma, urin19
Spatial metabolomics reveal mechanisms of dexamethasone against pediatric pneumonia19
Separation and purification of glycosides from medicinal plants based on strong polar separation medium with online closed-loop mode19
Equine in vivo metabolite profiling of the selective androgen receptor modulator LGD-3303 for doping control19
Selective and sensitive measurement of human neutrophil elastase in clinical samples based on a novel assay principle for protease activity measurement19
Development of a novel method for the simultaneous detection of trimethylamine N-oxide and creatinine in the saliva of patients with chronic kidney disease – Its utility in saliva as an alternative to19
Identification and quantification of markers in Azedarach Fructus and Toosendan Fructus19
Development of a fast and robust liquid chromatography-mass spectrometry-based metabolomics analysis method for neonatal dried blood spots19
Study on material basis and anti-hypertensive metabolomics of different extraction methods of the Uncaria rhynchophylla Scrophularia Formula19
Chemometric evaluation of repeatability of internal standard methods in high-performance liquid chromatography with a Japanese pharmacopoeia assay for indomethacin as an example19
Biosensing strategies for the detection of SARS-CoV-2 nucleic acids19
A feasible HPTLC method for concurrent quantitation of allopurinol-montelukast co-therapy in plasma and evaluation of their hepatic and renal effects in rats: Analytical, biochemical, and histopatholo19
Identification and characterization of forced degradation products of 5-hydroxymethyl-2-furaldehyde (5-HMF) by HPLC, LC-LTQ/Orbitrap and NMR studies19
Deciphering in vivo metabolic profile and pharmacological mechanisms of Jitongning Tablet for the treatment of Ankylosing spondylitis18
Use of qNMR to determine HPLC relative response factors for botanical reference standards used in pharmacopeial monographs18
A high-throughput analytical method for multiple DNA targets based on microdroplet PCR coupled with DGGE18
Characterization of antigen presentation capability for neoantigen-based products using targeted LC-MS/MS method18
Determination of famprofazone, amphetamine and methamphetamine in liver samples using enzymatic cell dispersion and SPE-LC-ESI-MS18
Editorial Board18
Understanding the retention mechanisms of a reversed-phase/anion exchange/cation-exchange column for the separation of epinephrine and norepinephrine18
Analysis of heparinase derived LMWH products using a MHC 2D LC system linked to Q-TOF MS18
Development and validation of a ligand-binding assay for quantification of the F(ab')2 antivenom of Daboia russelii siamensis in human serum and its application to a phase I clinical study18
Development by design of experiment and validation of a HPLC-UV method for simultaneous quantification of 1-nitro-2-phenylethane and methyleugenol: Application to nail permeation/retention studies18
A new strategy based on PCA for inter-batches quality consistency evaluation18
Determination of free sulfhydryl contents for proteins including monoclonal antibodies by use of SoloVPE18
Rapid determination of essential oils functional groups using compositional methods and VisNIR spectroscopy18
Amino acids analysis reveals serum methionine contributes to diagnosis of the Kawasaki disease in mice and children18
Facile synthesis of nickel phosphate nanorods as biomimetic enzyme with excellent electrocatalytic activity for highly sensitive detection of superoxide anion released from living cells18
Editorial Board18
Microdialysis as a sampling tool for the chemotherapeutic agent Doxorubicin18
Unraveling the mechanisms of Fenugreek seed for managing different gynecological disorders: steroidal saponins and isoflavones revealed as key bioactive metabolites18
Ligand fishing approach to explore Amaryllidaceae alkaloids as potential antiviral candidates targeting SARS-CoV-2 Nsp417
An immobilization of 2-(Aminomethyl) thiazole on multi-walled carbon nanotubes used for rapid extraction of manganese ions in hepatic patients17
HR/MS-based lipidome analysis of rat brain modulated by tolcapone17
Precolumn derivatization LC-MS/MS method to simultaneous quantitation of 10 monosaccharides in rat plasma17
Full evaporation headspace gas chromatography with thermal conductivity detection for the direct determination of water in solid pharmaceutical bulk products17
Editorial Board17
Editorial Board17
Synergistic mechanism of stir-baked curcumae radix with vinegar in dysmenorrhea rats based on UPLC-Q-TOF/MS metabolomics17
Development of the stability-indicating method, structural elucidation of new photodegradation products from terconazole by LC-MS TOF, and in vitro toxicity17
Determination of serum carbamazepine and its metabolite by validated tandem mass spectrometric method and the effect of carbamazepine on various hematological and biochemical parameters17
Optimization of the quantitative protocol for organic acid in fecal samples using gas chromatography-mass spectrometry17
Extraction and preconcentration of parabens from the human follicular fluid through dispersive micro solid phase extraction using microporous MIL-68 (In) followed by in-situ effervescence-boosted disp17
A high-throughput droplet digital PCR system aiming eight DNA methylation targets for age prediction17
Integrated cell metabolomics and network pharmacology approach deciphers the anti-testosterone deficiency mechanisms of Bushen Zhuanggu Tang17
Analysis of the polymerized impurities in cefmetazole sodium based on novel separation principle by liquid chromatography tandem ion trap/time-of-flight mass spectrometry17
Universal response method for the quantitative analysis of photodegradation impurities in lomefloxacin hydrochloride ear drops by liquid chromatography coupled with charged aerosol detector17
Pteridine and tryptophan pathways in children with type 1 diabetes: Isoxanthopterin as an indicator of endothelial dysfunction16
Validating a sensitive LCMS method for the quantitation of artemisinin in Artemisia spp. including material used in retracted clinical trials16
Structural characterization of novel hydrolytic and oxidative degradation products of acalabrutinib by LC-Q-TOF-MS, H/D exchange and NMR16
Editorial Board16
Screening and characterization of potential anti-gout components from Polygonum cuspidatum by integration off-line two-dimensional liquid chromatography-mass spectrometry with affinity ultrafiltration16
Novel quality control strategies for the determination of 25-hydroxyvitamin D by LC-MS/MS16
Stability of diazepam’s phase II metabolites in dried blood spots on filter paper16
A multicomponent LC-MS/MS method for drugs of abuse testing using volumetric DBS and a clinical evaluation by comparison with urine16
Vortex-blending matrix solid-phase dispersion and UPLC-Q-TOF/MS were proposed to extract and examine the urushiols from Toxicodendron vernicifluum bark16
Simultaneous determination of iguratimod and its metabolite in rat plasma using a UPLC-MS/MS method: Application for drug-drug interaction16
Characterization of interactions between local anesthetics and histamine H1 receptor by cell membrane chromatography model16
Study on the hydrolytic degradation behaviour of bictegravir by LC-PDA-Q/TOF-MS/MS NMR and in silico toxicity assessment16
Simultaneous determination of BGT-002 and its acyl glucuronide metabolite ZM326E-M2 in human plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study16
Separation and identification of a complex flurbiprofen-polyethylene glycol mono- and diester mixture via a hyphenated HPLC-DAD-HRMS/SPE NMR system16
Classification of polymorphic forms of fluconazole in pharmaceuticals by FT-IR and FT-NIR spectroscopy16
High-molecular weight impurity screening by size-exclusion chromatography on a reversed-phase column16
Pharmacokinetic and tissue distribution analysis of bioactive compounds from Fuke Qianjin capsules in rats by a validated UPLC MS/MS method16
Metabolic and lipidomic characterization of radioresistant MDA-MB-231 human breast cancer cells to investigate potential therapeutic targets16
Development and validation of a LC–MS/MS method for the quantification of phenolic compounds in human saliva after intake of a procyanidin-rich pine bark extract16
An evaluation of qH NMR: A complementary approach to GC-FID for quantification of Thymol and trans-Anethole in essential oils and supplements15
Enantioseparation and quantitative analysis of three alkaloids in Rhizoma Corydalis by chiral LC-MS/MS15
Protocol development, validation, and troubleshooting of in-situ fiber optic bathless dissolution system (FODS) for a pharmaceutical drug testing15
Untargeted GC/MS-based approach for identification of anti-inflammatory alkaloids from Hippeastrum elegans (Amaryllidaceae) using a human neutrophil model15
Simplification of pharmacopoeial liquid chromatography methods for related substances of statins by hyphenated ultraviolet and charged aerosol detection15
A sensitive UPLC-MS/MS method for the simultaneous determination of the metabolites in the tryptophan pathway in rat plasma15
A LC-MS-based serum pharmacochemistry approach to reveal the compatibility features of mutual promotion/assistance herb pairs in Xijiao Dihuang decoction15
Mass spectrometry imaging-based metabolomics highlights spatial metabolic alterations in three types of liver injuries15
Rapid quantitative detection of the discrepant compounds in differently processed Curcumae Rhizoma products by FT-NIR combined with VCPA-GA technology15
Urine proteome changes in a chronic unpredictable mild stress (CUMS) mouse model of major depressive disorder15
Co-stimulatory pathway competitive assay development using Liquid chromatography–tandem mass spectrometry (LC-MS/MS)15
In vivo and in vitro studies of Banhahoobak-tang tablets using UPLC-ESI-MS/MS with polarity switching15
Antiglycation, antioxidant and cytotoxicity activities of crude extract of Turnera ulmifolia L. before and after microencapsulation process15
“Plant Golden” C. sativus: Qualitative and quantitative analysis of major components in stigmas and petals and their biological activity in vitro15
Iris pseudacorus as an easily accessible source of antibacterial and cytotoxic compounds15
Boron nitride nanotubes for extraction of angiotensin receptor blockers from human plasma15
Development of a rapid and sensitive UPLC–MS/MS assay for simultaneous quantitation of Vorolanib and its metabolite in human plasma and application to a pharmacokinetics study15
Development of salting-out extraction methodology for the determination of piroxicam from polymeric based nanocarriers and biological samples14
Development and evaluation of a HILIC-MS method for the determination of amino acid and non-amino acid impurities in histidine14
Editorial Board14
Development of a platform method for rapid detection and characterization of domain-specific post-translational modifications in bispecific antibodies14
Ruxolitinib photodegradation mechanisms by theoretical and experimental chemistry14
A strategy for deciphering the bioactive metabolites of Farfarae Flos by the inter-individual variability of the antitussive effect14
Study on the effect of calibration standards prepared with different matrix on the accuracy of bile acid quantification using LC-MS/MS14
A targeted UHPLC-MS/MS method to monitor lipidomic changes during a physical effort: Optimization and application to blood microsamples from athletes14
Improving Chuanxiong Rhizoma quality standards using an effect-constituent index based bioassay14
High stability amino-derived reversed-phase/anion-exchange mixed-mode phase based on polysilsesquioxane microspheres for simultaneous separation of compound drugs14
Facile synthesis of surface functionalized Pd2+@P-CDP/COFs for highly sensitive detection of norfloxacin drug based on the host-guest interaction14
Analyzing proteolytic stability and metabolic hotspots of therapeutic peptides in two rodent pulmonary fluids14
Molecular classification and clinical diagnosis of acute-on-chronic liver failure patients by serum metabolomics14
Investigating the anti-atherosclerotic effects and potential mechanism of Dalbergia odorifera in ApoE-deficient mice using network pharmacology combined with metabolomics14
A burst of fenoterol excretion during the recovery of a weight loss protocol14
Characterization of chemotype-dependent terpenoids profile in cannabis by headspace gas-chromatography coupled to time-of-flight mass spectrometry14
Hybrid organic/inorganic hybrid surface technology for increasing the performance of LC/MS(MS)-based drug metabolite identification studies: Application to gefitinib and metabolites in mouse plasma an14
Development of a deep eutectic solvent-based ultrasound-assisted homogenous liquid-liquid microextraction method for simultaneous extraction of daclatasvir and sofosbuvir from urine samples14
Ultrasensitive detection of phenolphthalein in slimming products by gold-based immunochromatographic paper14
Recent advances in wearable medical diagnostic sensors and new therapeutic dosage forms for fever in children14
Chromatographic measurement of 3-hydroxyanthranilate 3,4-dioxygenase activity reveals that edaravone can mitigate the formation of quinolinic acid through a direct enzyme inhibition14
Identification and characterization of the in-vivo metabolites of the novel soluble epoxide hydrolase inhibitor EC5026 using liquid chromatography quadrupole time of flight mass spectrometry14
Reply to “Letter to the Editor 3,4-Methylenedioxymethamphetamine quantification via benchtop 1H qNMR spectroscopy: Method validation and its application to ecstasy tablets collected at music festivals14
A multiplex UPLC-MS/MS method for the quantification of three PD-L1 checkpoint inhibitors, atezolizumab, avelumab, and durvalumab, in human serum14
A simplified non-reduced peptide mapping method with faster and efficient enzymatic digestion for characterization of native disulfide bonds in monoclonal and bispecific antibodies14
A Systematic Analysis of the Effect of Extraction Solvents on the Chemical Composition of Extraction Solutions and the Analytical Implications in Extractables and Leachables Studies14
High-level structural analysis of proanthocyanidins using full collision energy ramp-MS2 spectrum14
Tyrosine and tryptophan in urine as biomarkers for prostate cancer: A validation study14
Development and validation of a sensitive and simple LC-MS/MS method for simultaneous quantitation of valsartan, sacubitril and sacubitrilat in pediatric population14
Rapid and accurate verification of drug identity, purity and quality by 1H-NMR using similarity calculations and differential NMR13
Phenolic composition and correlation with antioxidant properties of various organic fractions from Hertia cheirifolia extracts13
Quality assessment of Curcuma dietary supplements: Complementary data from LC-MS and 1H NMR13
Metabolomics and pharmacodynamic analysis reveal the therapeutic role of Prunella vulgaris oil on intrauterine adhesion rats13
Plasma metabolomic profiles reveal regulatory effect of chitosan oligosaccharides on loperamide-induced constipation in mice13
Purification free N-glycan analysis by capillary zone electrophoresis: Hunt for the lost glycans13
Drug discovery from natural products – Old problems and novel solutions for the treatment of neurodegenerative diseases13
Pharmacokinetic study of midazolam and α-hydroxymidazolam in guinea pig blood and hair roots after a single dose of midazolam13
A photonic dual nano-hybrid assay for detection of cell-free circulating mitochondrial DNA13
Characterization of phenolics and discovery of α-glucosidase inhibitors in Artemisia argyi leaves based on ultra-performance liquid chromatography-tandem mass spectrometry and relevance analysis13
The development and validation of a novel LC-MS/MS method for the simultaneous quantification of Molnupiravir and its metabolite ß-d-N4-hydroxycytidine in human plasma and saliva13
Development and clinical validation of a simple and fast UPLC-ESI-MS/MS method for simultaneous quantification of nine kinase inhibitors and two antiandrogen drugs in human plasma: Interest for their 13
Development of visualization and analysis methods for evaluating intratumoral nanoparticle kinetics for tumor-targeted drug delivery using Förster resonance energy transfer in vivo live imaging and ti13
The pharmacokinetic study of Tanreqing and the interaction with cefixime in rat model of pneumonia by validated UPLC-MS/MS13
Optimization of a rapid sample pretreatment for the quantification of COCAINE and its main metabolites in hair through a new and validated GC-MS/MS method13
Volumetric dried blood microsampling for monitoring imatinib mesylate therapy: Method development and clinical application in patients with chronic myeloid leukemia13
Effects of sulfur-fumigated ginseng on the global quality of Si-Jun-Zi decoction, a traditional ginseng-containing multi-herb prescription, evaluated by metabolomics and glycomics strategies13
Validation and application of a quantitative liquid chromatography tandem mass spectrometry assay for the analysis of rifapentine and 25-O-desacetyl rifapentine in human milk13
Real-time concentration monitoring using a compact composite sensor array for in situ quality control of aqueous formulations13
Determination of lithium concentration in capillary blood using volumetric dried blood spots13
Rapid screening of bioactive compound in Sanzi Yangqin Decoction and investigating of binding mechanism by immobilized β2-adrenogic receptor chromatography coupled with molecular docking13
Authentication of Hedyotis products by adaptor ligation-mediated PCR and metabarcoding13
Quantitative determination and characterization of polyphenols from Cissus quadrangularis L. and dietary supplements using UHPLC-PDA-MS, LC-QToF and HPTLC13
Quantification of anti-SARS-CoV-2 antibodies in human serum with LC-QTOF-MS13
LC-HRMS and NMR studies for characterization of forced degradation impurities of ponatinib, a tyrosine kinase inhibitor, insights into in-silico degradation and toxicity profiles13
Qualitative and quantitative comparison of flavor chemicals in tobacco heating products, traditional tobacco products and flavoring capsules13
Validation of an LC-MS/MS assay for the simultaneous determination of bictegravir, doravirine, and raltegravir in human plasma13
Recent applications of quantitative mass spectrometry in biopharmaceutical process development and manufacturing13
Determination of CYP450 activities in diabetes mellitus rats by a UHPLC-MS/MS method13
Obesity influences the microbiotic biotransformation of chlorogenic acid13
Quantitative determination of ICG-001 in rat plasma using HPLC-MS/MS: A pharmacokinetic study13
Development and validation of an LC-MS/MS methodology for the quantification of thyroid hormones in dko MCT8/OATP1C1 mouse brain13
Comparison of the metabolome in urine prior and eight weeks after radical prostatectomy uncovers pathologic and molecular features of prostate cancer12
Chiral LC-MS/MS method for the simultaneous determination of (R,S)-ketamine, (R,S)-norketamine, and (2R,6R;2S,6S)-hydroxynorketamine in mouse plasma and brain12
Quality evaluation of Pterocephali Herba through simultaneously quantifying 18 bioactive components by UPLC-TQ-MS/MS analysis12
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