Pharmaceutical Research

Papers
(The median citation count of Pharmaceutical Research is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Ethosomes as Nanocarriers for the Development of Skin Delivery Formulations105
Biodistribution and Non-linear Gene Expression of mRNA LNPs Affected by Delivery Route and Particle Size75
Nanoparticle-Mediated Cytoplasmic Delivery of Messenger RNA Vaccines: Challenges and Future Perspectives72
Applications, Challenges, and Outlook for PBPK Modeling and Simulation: A Regulatory, Industrial and Academic Perspective65
Review: Role of Model-Informed Drug Development Approaches in the Lifecycle of Drug Development and Regulatory Decision-Making63
Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery59
Enhanced Biosynthesis Synthesis of Copper Oxide Nanoparticles (CuO-NPs) for their Antifungal Activity Toxicity against Major Phyto-Pathogens of Apple Orchards54
Therapeutic Potential of Semaglutide, a Newer GLP-1 Receptor Agonist, in Abating Obesity, Non-Alcoholic Steatohepatitis and Neurodegenerative diseases: A Narrative Review47
Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain—a Game Changing Parameter for CNS Drug Discovery and Development46
Interactions of Lipids, Lipoproteins, and Apolipoproteins with the Blood-Brain Barrier43
Targeting Transporters for Drug Delivery to the Brain: Can We Do Better?40
Free Drug Theory – No Longer Just a Hypothesis?38
Taste Masking Study Based on an Electronic Tongue: the Formulation Design of 3D Printed Levetiracetam Instant-Dissolving Tablets36
Recent Developments on Ionic Liquids and Deep Eutectic Solvents for Drug Delivery Applications35
Antibiofilm Effects of Macrolide Loaded Microneedle Patches: Prospects in Healing Infected Wounds35
Performance of Area under the Concentration-Time Curve Estimations of Vancomycin with Limited Sampling by a Newly Developed Web Application34
Effect of Particle Size and Surface Charge on Nanoparticles Diffusion in the Brain White Matter33
Nanotechnology-Assisted Metered-Dose Inhalers (MDIs) for High-Performance Pulmonary Drug Delivery Applications32
Potential Application of Exosomes in Vaccine Development and Delivery31
Molecular, Solid-State and Surface Structures of the Conformational Polymorphic Forms of Ritonavir in Relation to their Physicochemical Properties30
Grand Challenges in Pharmaceutical Research Series: Ridding the Cold Chain for Biologics30
A Comprehensive Assessment of All-Oleate Polysorbate 80: Free Fatty Acid Particle Formation, Interfacial Protection and Oxidative Degradation29
Novel Curcumin-Resveratrol Solid Nanoparticles Synergistically Inhibit Proliferation of Melanoma Cells29
Recent Advancement and Technical Challenges in Developing Small Extracellular Vesicles for Cancer Drug Delivery27
Physiologically Based Pharmacokinetics Modeling in Biopharmaceutics: Case Studies for Establishing the Bioequivalence Safe Space for Innovator and Generic Drugs27
Analysis of Magneto-Hyperthermia Duration in Nano-sized Drug Delivery System to Solid Tumors Using Intravascular-Triggered Thermosensitive-Liposome27
Carboxylic Acid Counterions in FDA-Approved Pharmaceutical Salts26
A Machine Learning Approach to Predict Interdose Vancomycin Exposure26
Targeted Delivery of Combination Therapeutics Using Monoclonal Antibody 2C5-Modified Immunoliposomes for Cancer Therapy25
Development of CD133 Targeting Multi-Drug Polymer Micellar Nanoparticles for Glioblastoma - In Vitro Evaluation in Glioblastoma Stem Cells25
Olmesartan niosomes ameliorates the Indomethacin-induced gastric ulcer in rats: Insights on MAPK and Nrf2/HO-1 signaling pathway24
Quality Assurance of PBPK Modeling Platforms and Guidance on Building, Evaluating, Verifying and Applying PBPK Models Prudently under the Umbrella of Qualification: Why, When, What, How and By Whom?24
“Focused Ultrasound-mediated Drug Delivery in Humans – a Path Towards Translation in Neurodegenerative Diseases”24
The Use of Physiologically Based Pharmacokinetic Analyses—in Biopharmaceutics Applications -Regulatory and Industry Perspectives23
Susceptibility of Lung Carcinoma Cells to Nanostructured Lipid Carrier of ARV-825, a BRD4 Degrading Proteolysis Targeting Chimera23
Dual Encapsulated Dacarbazine and Zinc Phthalocyanine Polymeric Nanoparticle for Photodynamic Therapy of Melanoma23
Efficacy of Targeted ECO/miR-200c Nanoparticles for Modulating Tumor Microenvironment and Treating Triple Negative Breast Cancer as Non-invasively Monitored by MR Molecular Imaging22
Pharmacoproteomics of Brain Barrier Transporters and Substrate Design for the Brain Targeted Drug Delivery22
Identification of the specific causes of polysorbate 20 degradation in monoclonal antibody formulations containing multiple lipases22
Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates22
Strategies to improve the physicochemical properties of peptide-based drugs22
Novel 3D Printed Modular Tablets Containing Multiple Anti-Viral Drugs: a Case of High Precision Drop-on-Demand Drug Deposition22
Pharmacokinetic and Pharmacodynamic Modeling of siRNA Therapeutics – a Minireview22
Induced Pluripotent Stem Cells (iPSCs) Provide a Potentially Unlimited T Cell Source for CAR-T Cell Development and Off-the-Shelf Products21
Role of Surfactants on Release Performance of Amorphous Solid Dispersions of Ritonavir and Copovidone21
Modeling Approach to Predict the Impact of Inflammation on the Pharmacokinetics of CYP2C19 and CYP3A4 Substrates21
In Vitro - in Vivo Extrapolation of Hepatic Clearance in Preclinical Species20
BSA/Silver Nanoparticle-Loaded Hydrogel Film for Local Photothermal Treatment of Skin Cancer20
Revising Pharmacokinetics of Oral Drug Absorption: II Bioavailability-Bioequivalence Considerations20
Machine Learning Attempts for Predicting Human Subcutaneous Bioavailability of Monoclonal Antibodies20
Applications of Model-Based Meta-Analysis in Drug Development20
Re-writing Oral Pharmacokinetics Using Physiologically Based Finite Time Pharmacokinetic (PBFTPK) Models20
Folate Modified Long Circulating Nano-Emulsion as a Promising Approach for Improving the Efficiency of Chemotherapy Drugs in Cancer Treatment20
Dried Blood Spot Technique Applied in Therapeutic Drug Monitoring of Anticancer Drugs: a Review on Conversion Methods to Correlate Plasma and Dried Blood Spot Concentrations20
Size-Dependent Absorption through Stratum Corneum by Drug-Loaded Liposomes20
Natural Bioactive Compounds as Potential Browning Agents in White Adipose Tissue19
Recent Developments in Ionic Liquid-Assisted Topical and Transdermal Drug Delivery19
Role of Disease Progression Models in Drug Development19
Red Blood Cell Inspired Strategies for Drug Delivery: Emerging Concepts and New Advances19
Lipid Nanoparticles for Nucleic Acid Delivery to Endothelial Cells18
Nisin ZP, an Antimicrobial Peptide, Induces Cell Death and Inhibits Non-Small Cell Lung Cancer (NSCLC) Progression in vitro in 2D and 3D Cell Culture18
Ionic Liquids: Emerging Antimicrobial Agents18
Microneedle Mediated Iontophoretic Delivery of Tofacitinib Citrate18
Multiphysics Modeling and Simulation of Subcutaneous Injection and Absorption of Biotherapeutics: Model Development18
Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions18
Application of Confocal Raman Microscopy for the Characterization of Topical Semisolid Formulations and their Penetration into Human Skin Ex Vivo17
Optimization of Vancomycin Initial Dose in Term and Preterm Neonates by Machine Learning17
Subcutaneous Injection Site Pain of Formulation Matrices17
Co-Delivery Using pH-Sensitive Liposomes to Pancreatic Cancer Cells: the Effects of Curcumin on Cellular Concentration and Pharmacokinetics of Gemcitabine17
Challenges and Strategies to Enhance the Systemic Absorption of Inhaled Peptides and Proteins17
Spray Freeze Drying of Biologics: A Review and Applications for Inhalation Delivery17
Cannabidiol for the Treatment of Brain Disorders: Therapeutic Potential and Routes of Administration17
Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells17
Endosomal Escape of Bioactives Deployed via Nanocarriers: Insights Into the Design of Polymeric Micelles16
On the Use of Computational Fluid Dynamics (CFD) Modelling to Design Improved Dry Powder Inhalers16
Evaluating Dermal Pharmacokinetics and Pharmacodymanic Effect of Soft Topical PDE4 Inhibitors: Open Flow Microperfusion and Skin Biopsies16
Ligand Bound Fatty Acid Binding Protein 7 (FABP7) Drives Melanoma Cell Proliferation Via Modulation of Wnt/β-Catenin Signaling16
Multiphysics Modeling and Simulation of Subcutaneous Injection and Absorption of Biotherapeutics: Sensitivity Analysis16
Enhancement of the Mechanical and Drug-Releasing Properties of Poloxamer 407 Hydrogels with Casein16
High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT316
Development of a Spray-Dried Formulation of Peptide-DNA Nanoparticles into a Dry Powder for Pulmonary Delivery Using Factorial Design16
Exosomes as Carriers for Drug Delivery in Cancer Therapy16
Drug complexes: Perspective from Academic Research and Pharmaceutical Market15
A Review on Immunological Responses to SARS-CoV-2 and Various COVID-19 Vaccine Regimens15
Lipophilic Conjugates of Drugs: A Tool to Improve Drug Pharmacokinetic and Therapeutic Profiles15
Cefmetazole as an Alternative to Carbapenems Against Extended-Spectrum Beta-Lactamase-Producing Escherichia coli Infections Based on In Vitro and In Vivo Pharmacokinetics/Pharmacodynamics Experiments15
Biophysical, Molecular and Proteomic Profiling of Human Retinal Organoid-Derived Exosomes15
Current State and Opportunities with Long-acting Injectables: Industry Perspectives from the Innovation and Quality Consortium “Long-Acting Injectables” Working Group15
Inhaled Indomethacin-Loaded Liposomes as Potential Therapeutics against Non-Small Cell Lung Cancer (NSCLC)15
Can Extracellular Vesicles as Drug Delivery Systems Be a Game Changer in Cardiac Disease?15
Impact of Surfactants on the Performance of Clopidogrel-Copovidone Amorphous Solid Dispersions: Increased Drug Loading and Stabilization of Nanodroplets15
3D Printing Methyl Cellulose Hydrogel Wound Dressings with Parameter Exploration Via Computational Fluid Dynamics Simulation15
Translational Modeling Identifies Synergy between Nanoparticle-Delivered miRNA-22 and Standard-of-Care Drugs in Triple-Negative Breast Cancer15
High-Throughput, Fluorescence-Based Esterase Activity Assay for Assessing Polysorbate Degradation Risk during Biopharmaceutical Development15
Ionic Liquids: Promising Approach for Oral Drug Delivery15
Gel Strength of Hydrophilic Matrix Tablets in Terms of In Vitro Robustness14
Evaluating a Modified High Purity Polysorbate 20 Designed to Reduce the Risk of Free Fatty Acid Particle Formation14
Directing the Way—Receptor and Chemical Targeting Strategies for Nucleic Acid Delivery14
Uptake Pathway of Apple-derived Nanoparticle by Intestinal Cells to Deliver its Cargo14
Zinc Oxide Nanoparticles Promise Anticancer and Antibacterial Activity in Ovarian Cancer14
Antibody-Targeted Liposomes for Enhanced Targeting of the Blood-Brain Barrier14
Design, Fabrication and Evaluation of Stabilized Polymeric mixed micelles for Effective Management in Cancer Therapy13
Melt Crystallization of Celecoxib-Carbamazepine Cocrystals with the Synchronized Release of Drugs13
Effect of Fatty Acid Composition in Polysorbate 80 on the Stability of Therapeutic Protein Formulations13
CNS Delivery of Nucleic Acid Therapeutics: Beyond the Blood–Brain Barrier and Towards Specific Cellular Targeting13
Use of Bead Mixtures as a Novel Process Optimization Approach to Nanomilling of Drug Suspensions13
Optimizing the Design of Blood–Brain Barrier-Penetrating Polymer-Lipid-Hybrid Nanoparticles for Delivering Anticancer Drugs to Glioblastoma13
Current State and Challenges of Physiologically Based Biopharmaceutics Modeling (PBBM) in Oral Drug Product Development13
Berberine Improves the Protective Effects of Metformin on Diabetic Nephropathy in db/db Mice through Trib1-dependent Inhibiting Inflammation13
Strategy for Cytoplasmic Delivery Using Inorganic Particles13
Pulmonary Delivery of Emerging Antibacterials for Bacterial Lung Infections Treatment13
TPGS Decorated Liposomes as Multifunctional Nano-Delivery Systems13
Population Pharmacokinetic Analysis and Dosing Optimization Based on Unbound Daptomycin Concentration and Cystatin C in Nonobese Elderly Patients with Hypoalbuminemia and Chronic Kidney Disease12
Consideration of Fractional Distribution Parameter fd in the Chen and Gross Method for Tissue-to-Plasma Partition Coefficients: Comparison of Several Methods12
Emerging Technologies to Target Drug Delivery to the Skin – the Role of Crystals and Carrier-Based Systems in the Case Study of Dapsone12
The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infec12
Novel Deep Eutectic Solvent–Hydrogel Systems for Synergistic Transdermal Delivery of Chinese Herb Medicine and Local Treatments for Rheumatoid Arthritis12
The Effects of Solid Particle Containing Inks on the Printing Quality of Porous Pharmaceutical Structures Fabricated by 3D Semi-Solid Extrusion Printing12
The Role of Elevated Liver-Type Fatty Acid-Binding Proteins in Liver Diseases12
Light-Induced Histidine Adducts to an IgG1 Molecule Via Oxidized Histidine Residue and the Potential Impact of Polysorbate-20 Concentration12
Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides12
Exposure–Response Analysis of Osimertinib in EGFR Mutation Positive Non-Small Cell Lung Cancer Patients in a Real-Life Setting12
Fabrication of Polymeric Microneedles using Novel Vacuum Compression Molding Technique for Transdermal Drug Delivery12
Recent Update on Bacteria as a Delivery Carrier in Cancer Therapy: From Evil to Allies12
Understanding the Phagocytosis of Particles: the Key for Rational Design of Vaccines and Therapeutics12
Combination of co-crystal and nanocrystal techniques to improve the solubility and dissolution rate of poorly soluble drugs12
Predicting Viable Skin Concentration: Modelling the Subpapillary Plexus12
Advancement of the Infant Air-Jet Dry Powder Inhaler (DPI): Evaluation of Different Positive-Pressure Air Sources and Flow Rates12
Research on Preparation of 5-ASA Colon-Specific Hydrogel Delivery System without Crosslinking Agent by Mechanochemical Method11
Parametric Optimization of 3D Printed Hydrogel-Based Cardiovascular Stent11
SNAC for Enhanced Oral Bioavailability: An Updated Review11
Characterization of Biological Material Adsorption to the Surface of Nanoparticles without a Prior Separation Step: a Case Study of Glioblastoma-Targeting Peptide and Lipid Nanocapsules11
Towards a Better Understanding of the Post-Gastric Behavior of Enteric-Coated Formulations11
Ocular Physiologically Based Pharmacokinetic Modeling for Ointment Formulations11
RETRACTED ARTICLE: Nanoformulation of Apolipoprotein E3-Tagged Liposomal Nanoparticles for the co-Delivery of KRAS-siRNA and Gemcitabine for Pancreatic Cancer Treatment11
Assessing the Interrelationship of Microstructure, Properties, Drug Release Performance, and Preparation Process for Amorphous Solid Dispersions Via Noninvasive Imaging Analytics and Material Characte11
Simultaneous Pharmacokinetic Analysis of Nitrate and its Reduced Metabolite, Nitrite, Following Ingestion of Inorganic Nitrate in a Mixed Patient Population11
A Mechanistic Understanding of Monoclonal Antibody Interfacial Protection by Hydrolytically Degraded Polysorbate 20 and 80 under IV Bag Conditions10
In-Silico Screening of Lipid-Based Drug Delivery Systems10
Spray-Dried and Spray-Freeze-Dried Powder Formulations of an Anti-Interleukin-4Rα Antibody for Pulmonary Delivery10
Re-examining digoxin bioavailability after half a century: Time for changes in the bioavailability concepts10
PET Imaging in Preclinical Anti-Aβ Drug Development10
Ephedra Herb, Mao, Inhibits Antigen-Induced Mast Cell Degranulation by Induction of the Affinity Receptor for IgE Internalization10
Pharmaceutical Excipients Enhance Iron-Dependent Photo-Degradation in Pharmaceutical Buffers by near UV and Visible Light: Tyrosine Modification by Reactions of the Antioxidant Methionine in Citrate B10
miRNA Signature of Urine Extracellular Vesicles Shows the Involvement of Inflammatory and Apoptotic Processes in Diabetic Chronic Kidney Disease10
Evaluation of Intranasal Vaccine Delivery Using Anatomical Replicas of Infant Nasal Airways10
Dissolution Kinetics of Nifedipine—Ionizable Polymer Amorphous Solid Dispersion: Comparison Between Bicarbonate and Phosphate Buffers10
Transdermal Delivery of a Hydrogen Sulphide Donor, ADT-OH Using Aqueous Gel Formulations for the Treatment of Impaired Vascular Function: an Ex Vivo Study10
Oral Delivery of Nucleic Acid Therapies for Local and Systemic Action10
Defining Endocytic Pathways of Fucoidan-Coated PIBCA Nanoparticles from the Design of their Surface Architecture10
Review: Milk Small Extracellular Vesicles for Use in the Delivery of Therapeutics10
Inhibition of Insulin Degrading Enzyme to Control Diabetes Mellitus and its Applications on some Other Chronic Disease: a Critical Review10
Pharmacokinetics/Pharmacodynamics Evaluation of Flomoxef against Extended-Spectrum Beta-Lactamase-Producing Escherichia coli In Vitro and In Vivo in a Murine Thigh Infection Model10
In Vitro ADME and Preclinical Pharmacokinetics of Ulotaront, a TAAR1/5-HT1A Receptor Agonist for the Treatment of Schizophrenia10
Recent Advances in Inhaled Nanoformulations of Vaccines and Therapeutics Targeting Respiratory Viral Infections9
A Liposomal Gemcitabine, FF-10832, Improves Plasma Stability, Tumor Targeting, and Antitumor Efficacy of Gemcitabine in Pancreatic Cancer Xenograft Models9
Development and Evaluation of Dissolving Microarray Patches for Co-administered and Repeated Intradermal Delivery of Long-acting Rilpivirine and Cabotegravir Nanosuspensions for Paediatric HIV Antiret9
Calcium Enabled Remote Loading of a Weak Acid Into pH-sensitive Liposomes and Augmented Cytosolic Delivery to Cancer Cells via the Proton Sponge Effect9
Research and Education Needs for Complex Generics9
Direct Granule Feeding of Thermal Droplet Deposition 3D Printing of Porous Pharmaceutical Solid Dosage Forms Free of Plasticisers9
Dual Drug Loaded pH-sensitive Micelles for Efficient Bacterial Infection Treatment9
Enhancing the Cellular Production of Extracellular Vesicles for Developing Therapeutic Applications9
Spray Dried Rugose Lipid Particle Platform for Respiratory Drug Delivery9
Generation of Ophthalmic Nanosuspension of Prednisolone Acetate Using a Novel Technology9
Development of Physiology Based Pharmacokinetic Model to Predict the Drug Interactions of Voriconazole and Venetoclax9
The Mitochondrial mitoNEET Ligand NL-1 Is Protective in a Murine Model of Transient Cerebral Ischemic Stroke9
Lack of an Effect of Polysorbate 80 on Intestinal Drug Permeability in Humans9
Mathematical and Pharmacokinetic Approaches for the Design of New 3D Printing Inks Using Ricobendazole9
Effect of Insulin Receptor-Knockdown on the Expression Levels of Blood–Brain Barrier Functional Proteins in Human Brain Microvascular Endothelial Cells9
Application of a Two-Analyte Integrated Population Pharmacokinetic Model to Evaluate the Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Polatuzumab Vedotin in Patients with Non-H9
Prediction of Mefenamic Acid Crystal Shape by Random Forest Classification9
Thermodynamics and In-Plane Viscoelasticity of Anionic Phospholipid Membranes Modulated by an Ionic Liquid9
RETRACTED ARTICLE: Dual Blockade of PD-1 and LAG3 Immune Checkpoints Increases Dendritic Cell Vaccine Mediated T Cell Responses in Breast Cancer Model9
Reduced Fine API Agglomeration After Dry Coating for Enhanced Blend Uniformity and Processability of Low Drug Loaded Blends9
Challenges and Opportunities for Celecoxib Repurposing9
Pharmacokinetic/Pharmacodynamic Modeling of a Cell-Penetrating Peptide Phosphorodiamidate Morpholino Oligomer in mdx Mice9
Targeted Drug Delivery for Chronic Lymphocytic Leukemia9
In Vitro and In Silico Investigations on Drug Delivery in the Mouth-Throat Models with Handihaler®9
Participation of Monocarboxylate Transporter 8, But Not P-Glycoprotein, in Carrier-Mediated Cerebral Elimination of Phenytoin across the Blood-Brain Barrier9
Ocular Fluid Mechanics and Drug Delivery: A Review of Mathematical and Computational Models9
Progress in Intradermal and Transdermal Gene Therapy with Microneedles8
A Hybrid Algorithm Combining Population Pharmacokinetic and Machine Learning for Isavuconazole Exposure Prediction8
Surfactant-Free Glibenclamide Nanoparticles: Formulation, Characterization and Evaluation of Interactions with Biological Barriers8
The Interface Motion and Hydrodynamic Shear of the Liquid Slosh in Syringes8
Advancements in Particle Engineering for Inhalation Delivery of Small Molecules and Biotherapeutics8
Droplet-Based Microfluidic Tool to Quantify Viscosity of Concentrating Protein Solutions8
Brain Targeted Curcumin Loaded Turmeric Oil Microemulsion Protects Against Trimethyltin Induced Neurodegeneration in Adult Zebrafish: A Pharmacokinetic and Pharmacodynamic Insight8
Traditional Chinese Medicine “Pill”, an Ancient Dosage Form with Surprising Modern Pharmaceutical Characteristics8
Development of a Physiologically-Based Pharmacokinetic Model for Whole-Body Disposition of MMAE Containing Antibody-Drug Conjugate in Mice8
Which Analysis Approach Is Adequate to Leverage Clinical Microdialysis Data? A Quantitative Comparison to Investigate Exposure and Response Exemplified by Levofloxacin8
Strategies for Browning Agent Delivery8
Physiologically Based Biopharmaceutics Model for Selumetinib Food Effect Investigation and Capsule Dissolution Safe Space – Part I: Adults8
In Vitro Regional Deposition of Nasal Sprays in an Idealized Nasal Inlet: Comparison with In Vivo Gamma Scintigraphy8
In-Vivo and Ex-Vivo Brain Uptake Studies of Peptidomimetic Neurolysin Activators in Healthy and Stroke Animals8
Ionic Liquids-Based Drug Delivery: a Perspective8
Physiologically based Pharmacokinetic Models under the Prism of the Finite Absorption Time Concept8
Manufacturing Stable Bacteriophage Powders by Including Buffer System in Formulations and Using Thin Film Freeze-drying Technology8
The Implications of Drug-Polymer Interactions on the Physical Stability of Amorphous Solid Dispersions8
Investigation of Physical Properties of Disodium Etidronate Tetrahydrate and Application of Phosphorus K-Edge X-Ray Absorption Near-Edge Structure Spectroscopy8
Predicting Spray Dried Dispersion Particle Size Via Machine Learning Regression Methods8
Metal Ion Interactions with mAbs: Part 2. Zinc-Mediated Aggregation of IgG1 Monoclonal Antibodies8
Lipophilic Salts and Lipid-Based Formulations: Enhancing the Oral Delivery of Octreotide8
Drug Release from Surfactant-Containing Amorphous Solid Dispersions: Mechanism and Role of Surfactant in Release Enhancement8
Development of a Once-Daily Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK2982772 using DiffCORE Technology8
A Photopolymerized Semi-Interpenetrating Polymer Networks-Based Hydrogel Incorporated with Nanoparticle for Local Chemotherapy of Tumors7
Control of Drug-Excipient Particle Attributes with Droplet Microfluidic-based Extractive Solidification Enables Improved Powder Rheology7
Increasing Intracellular Levels of Iron with Ferric Ammonium Citrate Leads to Reduced P-glycoprotein Expression in Human Immortalised Brain Microvascular Endothelial Cells7
Lipid Microparticles Show Similar Efficacy With Lipid Nanoparticles in Delivering mRNA and Preventing Cancer7
Shedding Light on the Blood–Brain Barrier Transport with Two-Photon Microscopy In Vivo7
Temperature and Heat Transfer Control During Freeze Drying. Effect of Vial Holders and Influence of Pressure7
Role of Tissue Hydraulic Permeability in Convection-Enhanced Delivery of Nanoparticle-Encapsulated Chemotherapy Drugs to Brain Tumour7
Spray-Congealing and Wet-Sieving as Alternative Processes for Engineering of Inhalation Carrier Particles: Comparison of Surface Properties, Blending and In Vitro Performance7
Improved Transdermal Delivery of Rabies Vaccine using Iontophoresis Coupled Microneedle Approach7
pH-Dependent supersaturation from amorphous solid dispersions of weakly basic drugs7
Physiologically Based Pharmacokinetic Modeling of Rosuvastatin to Predict Transporter-Mediated Drug-Drug Interactions7
Simultaneous Targeting of Multiple oncomiRs with Phosphorothioate or PNA-Based Anti-miRs in Lymphoma Cell Lines7
Opportunities in an Evolving Pharmaceutical Development Landscape: Product Differentiation of Biopharmaceutical Drug Products7
Advanced Solid Formulations For Vulvovaginal Candidiasis7
Using Filters to Estimate Regional Lung Deposition with Dry Powder Inhalers7
Minimal Physiologically-based Pharmacokinetic Model to Investigate the Effect of Charge on the Pharmacokinetics of Humanized anti-HCV-E2 IgG Antibodies in Sprague–Dawley Rats7
Computational Fluid Dynamics (CFD) Guided Spray Drying Recommendations for Improved Aerosol Performance of a Small-Particle Antibiotic Formulation7
Friend or Foe: Xenobiotic Activation of Nrf2 in Disease Control and Cardioprotection7
Applications of Model Informed Drug Development (MIDD) in Drug Development Lifecycle and Regulatory Review7
Polymorphism of Pradofloxacin: Crystal Structure Analysis, Stability Study, and Phase Transformation Behavior7
Vehicles for Drug Administration to Children: Results and Learnings from an In-Depth Screening of FDA-Recommended Liquids and Soft Foods for Product Quality Assessment7
Peptide Isolation via Spray Drying: Particle Formation, Process Design and Implementation for the Production of Spray Dried Glucagon7
Physiologically-Based Pharmacokinetic Modeling of PAXLOVID™ with First-Order Absorption Kinetics7
Development of a Prototype, Once-Daily, Modified-Release Formulation for the Short Half-Life RIPK1 Inhibitor GSK29827727
Rational Development of Stable PYY3–36 Peptide Y2 Receptor Agonists7
Remodeling of Adipose Tissues by Fatty Acids: Mechanistic Update on Browning and Thermogenesis by n-3 Polyunsaturated Fatty Acids6
Dissolution Profiles of Carbamazepine Cocrystals with Cis–Trans Isomeric Coformers6
Densifying Co-Precipitated Amorphous Dispersions to Achieve Improved Bulk Powder Properties6
Epicutaneous Allergen Administration with Microneedles as a Novel Method of Immunotherapy for House Dust Mite (HDM) Allergic Rhinitis6
Surfactant Protection Efficacy at Surfaces Varies with the Nature of Hydrophobic Materials6
Prediction of Oral Drug Absorption in Rats from In Vitro Data6
A Physiology-Based Mathematical Model to Understand Drug Delivery from Contact Lenses to the Back of the Eye6
Correlative Image-Based Release Prediction and 3D Microstructure Characterization for a Long Acting Parenteral Implant6
Unambiguous Identification of Glucose-Induced Glycation in mAbs and other Proteins by NMR Spectroscopy6
Analysis of Host Cell Proteins in Monoclonal Antibody Therapeutics Through Size Exclusion Chromatography6
Trends in Light and Temperature Sensitivity Recommendations among Licensed Biotechnology Drug Products6
Testing Precision Limits of Neural Network-Based Quality Control Metrics in High-Throughput Digital Microscopy6
Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients6
An Enthalpy-Balance Model for Timewise Evolution of Temperature during Wet Stirred Media Milling of Drug Suspensions6
Azelaic Acid Promotes Caenorhabditis elegans Longevity at Low Temperature Via an Increase in Fatty Acid Desaturation6
Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib6
Uncovering the Role of Glycogen in Brown Adipose Tissue6
Delivery of Corn-Derived Nanoparticles with Anticancer Activity to Tumor Tissues by Modification with Polyethylene Glycol for Cancer Therapy6
Effect of Buffer Salts on Physical Stability of Lyophilized and Spray-Dried Protein Formulations Containing Bovine Serum Albumin and Trehalose6
Translational Modeling of Chloroquine and Hydroxychloroquine Dosimetry in Human Airways for Treating Viral Respiratory Infections6
PBPK Analysis to Study the Impact of Genetic Polymorphism of NAT2 on Drug-Drug Interaction Potential of Isoniazid6
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