OOIR: Observatory of International Research

Papers

(The median citation count of Biomedical Research-Tokyo is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Propranolol and landiolol inhibit cell proliferation enhanced by noradrenaline in human lung adenocarcinoma cells	15
RNA impacts formation of biomolecular condensates in the nucleus	10
The characteristics and prevalence of patent foramen ovale in Japanese people: a study using material from forensic autopsies	9
Multihormone-producing capabilities of normal pancreatic islet cells—spatial transcriptomics analysis using Xenium	9
Pro-gastrin-releasing peptide expression in Ewing sarcoma cells in vitro and in vivo demonstrates its availability as a valuable tumor marker	9
Quercetin protects human coronary artery endothelial cells against hypoxia/reoxygenation-induced mitochondrial apoptosis via the Nrf2/HO-1 axis	8
Intragastric administration of cuminaldehyde, a natural TRPA1 agonist, enhanced carbohydrate oxidation and reduced body fat accumulation in mice	8
Novel cell-based system to assay cell-cell fusion during myotube formation	8
Histological observation on the initial stage of vascular invasion into the secondary ossification of murine femoral epiphyseal cartilage	7
Spontaneous calcium responses of SF2 rat dental epithelial cells stably expressing the calcium sensor G-GECO	7
Methionine oxidation of TRPV2 regulates thermogenesis in brown adipocytes	6
IL-33 deficiency suppresses alveolar bone loss in a ligature-induced periodontitis model	6
Effects of ANP and BNP on the generation of respiratory rhythms in brainstem–spinal cord preparation isolated from newborn rats	6
Selective estrogen receptor modulators, acting as agonists of estrogen receptor α in osteoblasts, reduce the TGF-β-induced synthesis of macrophage colony-stimulating factor via inhibition of JNK signa	6
Serotonin reuptake inhibitor suppresses the activation of human platelets by a combination of thrombopoietin and collagen through inhibition of Rac and Rho/Rho-kinase	5
Gastric biopsy-derived cell line and its utility in assessing tumor cell drug sensitivity	5
Visualization of the localization of phospholipids in developing rat teeth by matrix-assisted laser desorption/ionization imaging mass spectrometry	5
Mitochondrial DNA copy number variations in Epstein-Barr virus-transformed B cells after exposure to radiation: A possible biomarker for dose assessment	4
A mathematical model of kinetochore-microtubule attachment regulated by Aurora A activity gradient describes chromosome oscillation and correction of erroneous attachments	4
Blockade of CD80/CD86-CD28 co-stimulation augments the inhibitory function of peptide antigen-specific regulatory T cells	4
The mouse experimental periodontitis by silk-ligature placement triggers systemic inflammation potentially exacerbating pulmonary inflammation	4
Efficacy of 1,5-anhydro-D-fructose on reducing mental stress: a randomized, double-blind, placebo-controlled trial—a pilot study	3
The lncRNA ADAMTS9-AS1/miR-185-5p/KAT7 ceRNA network inhibits cardiomyocyte hypertrophy in hypertrophic obstructive cardiomyopathy	3
CLN6’s luminal tail-mediated functional interference between CLN6 mutants as a novel pathomechanism for the neuronal ceroid lipofuscinoses	3
Inhibition of skeletal muscle differentiation by calciprotein particles in human primary myoblasts	3

3-Iodothyronamine, a trace amine-associated receptor agonist, regulates intracellular Ca2+ increases via CaMK II through Epac2 in rat cerebral arterioles	3
Erratum to: Efficacy of 1,5-anhydro-D-fructose on reducing mental stress: a randomized, double-blind, placebo-controlled trial—a pilot study	3
Activation of STAT3 (signal transducer and activator of transcription 3) in synovial tissues from the hip joint in the early stage of rapidly destructive coxopathy	3
Effects of linalool on respiratory neuron activity in the brainstem-spinal cord preparation from newborn rats	3
The effect of the formalin-fixed paraffin-embedded process on salivary microbiota profiling	3
Secondary bile acid lithocholic acid attenuates neurally evoked ion transport in the rat distal colon	3
Early reperfusion with hemoglobin vesicles into tracheal subepithelial capillaries in a mouse tracheal transplant model	2
The distinct effect between Amyloid β (1‒40) and Amyloid β (1‒42) on the TRAP-stimulated platelet activation in diabetes mellitus	2
Mumefural prevents insulin resistance and amyloid-beta accumulation in the brain by improving lowered interstitial fluid pH in type 2 diabetes mellitus	2
Calcium phosphate controls nucleation and growth of calcium oxalate crystal phases in kidney stones	2
Structure and barrier functions of the perineurium and its relationship with associated sensory corpuscles: A review	2
Oncostatin M reduces the synthesis of macrophage-colony stimulating factor stimulated by TGF-β via suppression of p44/p42 MAP kinase and JNK in osteoblasts	2
Diet-related changes of basal lamina fenestrations in the villous epithelium of the rat small intestine: Statistical analysis on scanning electron microscopy	2
Nicotinamide mononucleotide augments the cytotoxic activity of natural killer cells in young and elderly mice	2
Red foxtail millet upregulates brain-derived neurotrophic factor levels in vitro and in vivo	2
Fractalkine’s dual role in inflammation and hard tissue formation in cultured human dental pulp cells	1
Cell cycle dependence of cell survival following exposure to X-rays in synchronous HeLa cells expressing fluorescent ubiquitination-based cell cycle indicators	1
Finerenone alleviates the high glucose-induced fibrosis in HK-2 cells by inhibiting EMT via the TGF-β1/Smads signaling	1
<i>Meis1</i> plays roles in cortical development through regulation of cellular proliferative capacity in the embryonic cerebrum	1
Long non-coding RNA TUG1 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells by regulating the AMPK/mTOR/autophagy pathway	1
Changes in 5-hydroxytryptamine and its metabolite, 5-hydroxyindole-acetic acid, levels in the brain of rats administered with methotrexate	1
Neonatal isoflurane exposure disturbs granule cell migration in the rat dentate gyrus	1
Disposal of intestinal apoptotic epithelial cells and their fate via divergent routes	1
Mycophenolate mofetil reduces cell viability associated with the miR-205-PAX9 pathway in human lip fibroblast cells	1
Rutin promotes M2 phenotype microglia polarization by suppressing the JAK/STAT3 signaling to protect against retinal ischemia-reperfusion injury	1
Modulation of myocardial injury in polymicrobial sepsis: The dual role of interleukin-13 in cardiac inflammation and stress	1
Indoxyl sulfate contributes to colorectal cancer cell proliferation and increased EGFR expression by activating AhR and Akt	1
Silibinin promotes melanogenesis through the PKA and p38 MAPK signaling pathways in melanoma cells	1
Protective effects of chlorogenic acid on capillary regression caused by disuse muscle atrophy	1
SPERT gene silencing inhibits the growth of human colon cancer xenograft tumor in nude mice via p38MAPK/HSP27 signaling pathway	1
Effects of inactivity and exercise intervention on brain-derived neurotrophic factor in mice: Comparison of kinetics in serum, skeletal muscle, and brain	1
Anatomical background of the sensory function in the urethra: involvement of endocrine paraneurons and afferent nerves in divergent urogenital functions. A review	1
Disturbance on drug efficacy of dapagliflozin, an SGLT2 inhibitor, in mice	1
Fish oil consumption prevents hepatic lipid accumulation induced by high-cholesterol feeding in obese KK mice	1