OOIR: Observatory of International Research

Papers

(The median citation count of Biomedical Research-Tokyo is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Propranolol and landiolol inhibit cell proliferation enhanced by noradrenaline in human lung adenocarcinoma cells	12
The characteristics and prevalence of patent foramen ovale in Japanese people: a study using material from forensic autopsies	10
RNA impacts formation of biomolecular condensates in the nucleus	9
Quercetin protects human coronary artery endothelial cells against hypoxia/reoxygenation-induced mitochondrial apoptosis via the Nrf2/HO-1 axis	9
Histological observation on the initial stage of vascular invasion into the secondary ossification of murine femoral epiphyseal cartilage	8
Intragastric administration of cuminaldehyde, a natural TRPA1 agonist, enhanced carbohydrate oxidation and reduced body fat accumulation in mice	8
Novel cell-based system to assay cell-cell fusion during myotube formation	8
IL-33 deficiency suppresses alveolar bone loss in a ligature-induced periodontitis model	7
Spontaneous calcium responses of SF2 rat dental epithelial cells stably expressing the calcium sensor G-GECO	7
Selective estrogen receptor modulators, acting as agonists of estrogen receptor α in osteoblasts, reduce the TGF-β-induced synthesis of macrophage colony-stimulating factor via inhibition of JNK signa	6
Effects of ANP and BNP on the generation of respiratory rhythms in brainstem–spinal cord preparation isolated from newborn rats	6
Visualization of the localization of phospholipids in developing rat teeth by matrix-assisted laser desorption/ionization imaging mass spectrometry	5
Gastric biopsy-derived cell line and its utility in assessing tumor cell drug sensitivity	5
Serotonin reuptake inhibitor suppresses the activation of human platelets by a combination of thrombopoietin and collagen through inhibition of Rac and Rho/Rho-kinase	5
3-Iodothyronamine, a trace amine-associated receptor agonist, regulates intracellular Ca2+ increases via CaMK II through Epac2 in rat cerebral arterioles	4
A mathematical model of kinetochore-microtubule attachment regulated by Aurora A activity gradient describes chromosome oscillation and correction of erroneous attachments	4
Efficacy of 1,5-anhydro-D-fructose on reducing mental stress: a randomized, double-blind, placebo-controlled trial—a pilot study	4
Blockade of CD80/CD86-CD28 co-stimulation augments the inhibitory function of peptide antigen-specific regulatory T cells	4
The mouse experimental periodontitis by silk-ligature placement triggers systemic inflammation potentially exacerbating pulmonary inflammation	4
Effects of linalool on respiratory neuron activity in the brainstem-spinal cord preparation from newborn rats	4
Mitochondrial DNA copy number variations in Epstein-Barr virus-transformed B cells after exposure to radiation: A possible biomarker for dose assessment	4
The lncRNA ADAMTS9-AS1/miR-185-5p/KAT7 ceRNA network inhibits cardiomyocyte hypertrophy in hypertrophic obstructive cardiomyopathy	4
Calcium phosphate controls nucleation and growth of calcium oxalate crystal phases in kidney stones	3
CLN6’s luminal tail-mediated functional interference between CLN6 mutants as a novel pathomechanism for the neuronal ceroid lipofuscinoses	3
The effect of the formalin-fixed paraffin-embedded process on salivary microbiota profiling	3

Activation of STAT3 (signal transducer and activator of transcription 3) in synovial tissues from the hip joint in the early stage of rapidly destructive coxopathy	3
Erratum to: Efficacy of 1,5-anhydro-D-fructose on reducing mental stress: a randomized, double-blind, placebo-controlled trial—a pilot study	3
Inhibition of skeletal muscle differentiation by calciprotein particles in human primary myoblasts	3
Secondary bile acid lithocholic acid attenuates neurally evoked ion transport in the rat distal colon	3
Diet-related changes of basal lamina fenestrations in the villous epithelium of the rat small intestine: Statistical analysis on scanning electron microscopy	2
Mumefural prevents insulin resistance and amyloid-beta accumulation in the brain by improving lowered interstitial fluid pH in type 2 diabetes mellitus	2
Long non-coding RNA TUG1 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells by regulating the AMPK/mTOR/autophagy pathway	2
Oncostatin M reduces the synthesis of macrophage-colony stimulating factor stimulated by TGF-β via suppression of p44/p42 MAP kinase and JNK in osteoblasts	2
Early reperfusion with hemoglobin vesicles into tracheal subepithelial capillaries in a mouse tracheal transplant model	2
Nicotinamide mononucleotide augments the cytotoxic activity of natural killer cells in young and elderly mice	2
Red foxtail millet upregulates brain-derived neurotrophic factor levels in vitro and in vivo	2
Structure and barrier functions of the perineurium and its relationship with associated sensory corpuscles: A review	2
Modulation of myocardial injury in polymicrobial sepsis: The dual role of interleukin-13 in cardiac inflammation and stress	2
Indoxyl sulfate contributes to colorectal cancer cell proliferation and increased EGFR expression by activating AhR and Akt	2
Fish oil consumption prevents hepatic lipid accumulation induced by high-cholesterol feeding in obese KK mice	1
Cell cycle dependence of cell survival following exposure to X-rays in synchronous HeLa cells expressing fluorescent ubiquitination-based cell cycle indicators	1
CD44 as a pathological marker for the early detection of calcineurin inhibitor-induced nephrotoxicity post kidney transplantation	1
Specific inhibition of α5 subunit-containing GABA<sub>A</sub> receptors enhances locomotor activity and neuronal activity in the motor cortex	1
Disposal of intestinal apoptotic epithelial cells and their fate via divergent routes	1
Effects of inactivity and exercise intervention on brain-derived neurotrophic factor in mice: Comparison of kinetics in serum, skeletal muscle, and brain	1
Rutin promotes M2 phenotype microglia polarization by suppressing the JAK/STAT3 signaling to protect against retinal ischemia-reperfusion injury	1
Neonatal isoflurane exposure disturbs granule cell migration in the rat dentate gyrus	1
Mycophenolate mofetil reduces cell viability associated with the miR-205-PAX9 pathway in human lip fibroblast cells	1
Pathological examination of Ym1, a chitinase family protein, in <i>Mesocestoides corti</i>-infected mice	1
Validation of mitotic harvesting method with human cervical carcinoma HeLa cells expressing fluorescent ubiquitination-based cell cycle indicators for radiation research	1
Changes in 5-hydroxytryptamine and its metabolite, 5-hydroxyindole-acetic acid, levels in the brain of rats administered with methotrexate	1
Anatomical background of the sensory function in the urethra: involvement of endocrine paraneurons and afferent nerves in divergent urogenital functions. A review	1
Fractalkine’s dual role in inflammation and hard tissue formation in cultured human dental pulp cells	1
Protective effects of chlorogenic acid on capillary regression caused by disuse muscle atrophy	1
SPERT gene silencing inhibits the growth of human colon cancer xenograft tumor in nude mice via p38MAPK/HSP27 signaling pathway	1
Protective effects of hachimijiogan (HJG), a Japanese Kampo medicine, on cancer cachectic muscle wasting in mice	1
Role of aquaporin 5 and glandular blood flow in the acetylcholine-induced secretion of saliva in rats	1
Silibinin promotes melanogenesis through the PKA and p38 MAPK signaling pathways in melanoma cells	1
<i>Meis1</i> plays roles in cortical development through regulation of cellular proliferative capacity in the embryonic cerebrum	1