OOIR: Observatory of International Research

Papers

(The TQCC of Heterocycles is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Contents	34
Contents	11
A Series of Novel Coumarin Derivatives: Design, Synthesis and Evaluation of Anti-Tumor Activity	11
Diversity-Oriented Synthesis of 2-Substituted Purine Nucleosides from Available Nucleosides via the Late-Stage Nitration/Derivatization	7
Synthesis of Novel 2,3-Disubstituted Thiophenes via Tandem Thia-Michael/Aldol Reaction of Allenyl Esters	7
Substituent Effects on Physical Properties of Azole Based Ionic Liquids	7
Synthesis, Characterization and Biological Screening of New N-Substituted-7-chloro-4-hydroxy-2-quinolone-3-carboxamides as Promising Anticancer Agents	6
Synthesis of 2-Trifluoroacetonyl-3-alkyl/alkoxychromones and Their Reactions with 1,2-Bidentate Nucleophiles	6
Inhibition of Amyloid-β Aggregation by p-Terphenyls from the Mushroom Polyozellus multiplex and Their Neuroprotective Effects	6
Synthesis and Stereochemical Analysis of Planar Chiral Nine-Membered Aza-Orthocyclophyne	5
Azuleno[6,5-b]indoles: Palladium-Catalyzed Oxidative Ring-Closing Reaction of 6-(Arylamino)azulenes	5
Synthesis and Antimicrobial Activity of 2,5-bis(Pyrazol-3-yl or Triazol-4-yl)-1,3,4-oxadiazoles	5
Direct Arylation of Benzothiophene and Benzofuran Catalyzed by a Dinuclear Palladium Complex	5
A New Natural Butenolide, (5R)-3-Tetradecyl-5-methyl-2(5H)-furanone, from Octocoral Cladiella conifera	4
Strategy for the Synthesis of C-Aryl Glucosides as Sodium Glucose Cotransporter 2 Inhibitors	4
Synthesis and Antitumor Activity of Heterocylic Aurone and Its Analogue Indanone Derivatives	4
N-Heterocyclic Analogs of Indenocorannulene	4
Isolation of Ikahonone, 4-Methyl-2,4-dihydroxy-3-pentanone from Bacillus cereus IFM12235	4
Synthesis of Penicolinates A, C and D	4
Design and Synthesis of New Quinoline Linked to Pyranotriazolopyrimidines Conjugates as Novel Targets to Discover Promising Anti-SARS-COV-2	4
Synthesis of 2,3-Anthracenedicarboxylic-acid-derived Fluorophore and Chemiluminophore Incorporating Dipicolylaminomethyl Receptors, and Their Luminescence Responses to Metal Ions	4
N-Alkylation of Azoles with Enones Assisted by P(III) or Fe2O3-Nanoparticles as Recyclable Catalyst	4
Concise Synthesis of (±)-Cephalotaxine	4
3-[2-Oxo-2H-chromen-3(6)(8)-yl]-1-aryl/heteroaryl-1H-pyrazole-4-carbaldehydes: Synthesis, Reactions and Applications	4
A Convenient Synthesis of 1,2,4-Triazino[2,3-b]indazol-3-amine Derivatives via Tandem Abnormal Staudinger/Aza-Wittig/Isomerization Reaction	3

An Efficient Method for the Synthesis of N-Aryl Substituted C1-Functionalized 1,2,3,4-Tetrahydroisoquinolines	3
Design, Synthesis and Evaluation of Catechol-Based Amyloid Beta Aggregation Inhibitors	3
Synthesis and Fungicidal Activities of 5-Aryl-1,3,4-oxadiazolyl 2-Thioether Derivatives Containing Strobilurin Motif	3
Synthesis of Covalent Boroxine Frameworks by Polycondensation of Tetrahydroxydiboron	3
A Review on the Biological Activity of β-Carboline Derivatives	3
Mechano-Biocatalytic Rapid Synthesis of 2-Amino-3-cyano-4H-pyran Derivatives	3
Chemical Structures and Cell Death Inducing Activities of Constituents Isolated from Hibiscus tiliaceus	3
Contents	3
2-Arylazoimidazoles Revamped by Quarternization or Dimerization; Another Gain in Functionality of an Industrial Dyestuff Family by Task-Specific Side-Chain Substituents	3
Synthesis and Utilization of Tetrahydronaphthalene-1,3-dicarbonitrile as a Source of Benzo[f]quinazoline, Pyridine, Imidazole Derivatives with Antitumor Activity and Molecular Docking and Dynamics Stu	3
Three-Component Synthesis of Tetrahydrobenzo[b]pyrans Catalyzed by Sodium Cyclamate	3
A Review on Indole[2,3-a]quinolizidine: The Synthetic Approaches to the Development of Bioactive Indolo[2,3-a]quinolizidine Scaffolds	3
Syntheses of Two New Fluorous Crown Ethers Carrying Sugar Molecules with a Multivalent Bfp Modification: Investigations of Their Partition Ratios in Fluorous Biphasic Systems and Recyclability During	3
Novel Synthesis and Properties of Optically Pure N-Trifluoroacetylphenylglycine Hydroxysuccinimide Ester	3
New Bioactive Sesquiterpenoid from Malaysian Soft Coral Genus Lemnalia	3
Triazene-Bridged Nitrogen-Rich Heterocyclic Energetic Compounds 4,4'-(Triaz-1-ene-1,3-diyl)bis(1,2,5-oxadiazol-3-amine) - Synthesis, Characterization and Properties	3
One-Pot Synthesis of Fully Substituted Oxazol-2-amines via Staudinger/Aza-Wittig/Isomerization Reaction	3
Design, Synthesis and Biological Evaluation of Pyrimidinamine Derivatives Containing Urea Moiety	3
Rapid, Environmentally Greener and Ultrasound-Assisted One-Pot Synthesis of Quinoline, Benzimidazole and Pyrimidine Combined Moiety as Potential Antimicrobial Agents	2
Selective Synthesis of 2,2-Diamino-4,4,6,6-tetrakis(aryloxy)cyclotriphosphazenes N3P3-2,2-(NH2)2-4,4,6,6-(ArO)4	2
Design and Synthesis of 1,3-Bis(3-(trifluoromethyl)diazirin-3-yl)phenylalanine for Efficient Photo Cross-Linking	2
Microwave-Assisted Approach to Nitroaniline/Aminopyridine and Its Inhibition Activity of Seed Germination	2
Application of Reversible Detection Method for N-Terminus Amino Groups: Solid Phase Synthesis of Stylissatin B	2
Novel Pyrazolines and Benzothiazepines as Tubulin Polymerization Inhibitors: Synthesis, Biological Evaluation, and Molecular Docking	2
Contents	2
Asymmetric Intramolecular Aldol Reactions Mediated by Chiral Triamines Bearing a Pyrrolidine Scaffold to Provide a Wieland–Miescher Ketone	2
Diterpenoid Alkaloids from Aconitum elliotii Lauener	2
Supramolecular Chirogenesis in Amide-Linked Bis(Zinc Porphyrin): Application for Absolute Configurational Assignment of Chiral Calboxylic Acids and Chiral Amino Acids	2
A New C,C-Linked Functionalized Bipyrazole: Synthesis, Crystal Structure, Spectroscopies and DFT Studies. Evaluation of the Antibacterial Activity and Catalytic Properties	2
Large-Scale Synthesis of the Key Intermediates of Tetrahydropyran Derivatives under Flow Conditions	2
Antiviral Activity of Some C3-Symmetrical N-Methyl Benzylamine-Substituted 1,3,5-Triazines and Related Compounds	2
Synthesis of Hexahydroquinoline-3-carboxamide Derivatives and Their HIV-1 Antiviral Activity	2
Heterocycles Award	2
Synthesis of Hepta-arbutin-branched β-Cyclodextrins at Their Primary Sides via Click Reaction	2
Acid, Metal and Peroxide-Free Synthesis of 2,4,5-Trisubstituted Imidazoles Commencing from Internal Alkenes Using an Iodine/DMSO System	2
Contents	2
Briarane-Type Diterpenoids from the Cultured Octocoral Briareum stechei (Kükenthal, 1908)	2
Synthesis, Characterization, Molecular Docking Studies and Antimicrobial Activity of Azomethine Derivatives of 1,3-Substituted Pyrazoles	2
Synthesis of 2-Anilino-2,4,4,6,6-pentachlorocyclotriphosphazenes (N3P3Cl5(NAr(R)))	2
Iodine-Promoted Cyclization of Alkylidene Barbiturates in Water: Facile Synthesis of Dihydrofuryl Spirobarbiturates	2
A Comprehensive Study of Pyrimidine and Its Medicinal Applications	2
An Efficient Route for the Synthesis of 2-Arylbenzothiazoles in an Ionic Liquid, Using Ultrasound Irradiation	1
Transnitrosation of Alicyclic N-Nitrosamines Containing Sulfur Atoms in Five- or Six-Membered Rings	1
Click Chemistry toward the Synthesis of Anticancer Agents	1
Diterpene Glycosides Derived from Aster spathulifolius Have Immunomodulatory Effects	1
Design, Synthesis and Biological Evaluation of Novel Indole-Containing Sorafenib Derivatives	1
A New Monoterpenoid Indole Alkaloid from Uncaria rhynchophylla	1
Synthesis, Antioxidant Activity and Molecular Docking of Some New Thiazolyl-Pyrazolinyl-Pyran-2-One Derivatives	1
FAB-MS Measurement of 2-Hydroxyestrone and Monosaccharides Assisted by 4-Pyridineboronic Ester Derivatization	1
Fischer Glycosidation Using Organotitanium Catalyst ORGATIX	1

Silver-Catalyzed Conversion of CO2 and 2-Ethynylanilines into 4-Hydroxyquinolin-2(1H)-ones in Protic Ionic Liquid at Atmospheric Pressure	1
Efficient One-Pot, Three-Step Synthesis of 1,2,3,5-Tetrasubstituted Pyrroles via Aza-Michael Addition of Methyl 3-Iminoacrylates	1
A Convenient One-Pot Synthesis of Novel 1,4-Dihydro-1,2-Benzoxaphosphinino[4,3-C]Pyrazoles	1
Characterization and Antitumor Activity of Furazano[3,4-g]pteridine-2,4(1H,3H)-dione	1
Contents	1
Synthesis and Radical Scavenging Activity of Substituted Dihydrobenzofuran-5-ols	1
Diastereoselective Synthesis of 2,8-Dioxabicyclo[3.3.1]Nonane Derivatives via I2-Mediated Cascade Reactions	1
The Continuous-flow Synthesis of 1H-Indazoles via Reaction of o-Fluorobenzaldehydes with tert-Butyl Carbazate under High Teperature	1
Reaction Pathway and Kinetic Study of 4,5-Dihydroxyimidazolidine-2-thione Synthesis by HPLC and NMR	1
New Dimeric Cytisine-Type Alkaloid and Lavandulyl Biflavonoid from Sophora flavescens AIT. and Their Inhibitory Effect on Cancer Cells	1
Sparsomycin – a Review and Re-assessment	1
Heterocycles Award	1
Regiodivergent Medium-Ring Oxasilacycle Synthesis from Diallylsilanes	1
Microwave-Assisted Synthesis of Phenylisoxazole Derivatives via 1,3-Dipolar Cycloaddition	1
Evaluation of 4,4'-Diaminodiphenylmethane as a Platform for Proton, pH, and Metal Ion Responsive Fluorescent Probe	1
Three New Nervogenic Acid Derivatives from Liparis nervosa	1
Improved Synthesis of Naldemedine Tosylate and Crystal Structures of Four Related Solid Forms	1
Contents	1
Synthesis of N3-Substituted Quinazoline-2,4-diones via C-4 Amination-Cyclization of Isatoic Anhydrides	1
Design, Synthesis, and Biological Evaluation of 4H-Pyrido[1,2-a]pyrimidin-4-one Derivatives as Anticancer Agents via ROR1 Inhibition	1
A Transition Metal-Free System for C3-H Nitrosation of Imidazo[1,2-a]pyridine Using Sodium Nitrite at Room Temperature	1
Contents	1
Ultrasound Assisted One Pot, Three-Component Reaction for Facile Design of Novel 1,2,3-Diazaphosphole, 1,5,2-Diazaphosphinine and 1,5,2-Diazaphosphepine Compounds Containing Coumarin Ring	1
Stereospecific Skeletal Rearrangement of Epoxides Derived from Methylenecyclobutane-Fused N-Heterocycles	1
Contents	1
Diversity-Oriented, One Step Synthesis of Chromeno[2,3-b]Indoles and Thiochromeno[2,3-b]Indoles under Microwave-Assisted Conditions	1
Diastereoselective Synthesis of Amide-Bridged Axially Chiral Biaryls through Point-to-Axial Asymmetric C-H Arylation	1
Contents	1
Synthetic Approaches for Construction of Novel Angular Heterocyclic Systems Containing Chromeno[2,3-b]quinoline	1
Chiral 1,2-Diaminocyclohexane-α-Amino Acid-Derived Amidphos/Ag(I)-Catalyzed Divergent Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides	1
The Utility of Oxoammonium Species in Organic Synthesis: Beyond Alcohol Oxidation	1
Functionalization of Phenothiazine Derivatives by Ammonium Bridge	1
An Unprecedented Synthesis of 8b-Hydroxy-3a-(1H-pyrrol-2-yl)/(1H-indol-3-yl)-3a,8b-dihydroindeno[1,2-b]pyrrol-4(1H)-one Derivatives from Pyrrole/Indole with Ninhydrin and β‑Enaminocarbonyls	1
New C19-Diterpeniod Alkaloids from Aconitum novoluridum	1
Theoretical Investigation on the Mechanism and Selectivity of Catalyst-Free Annulation of Ynediones and (Iso)quinoline N-Oxides	1
Diterpenoid Alkaloids from Delphinium pachycentrum Hemsl.	1
Total Synthesis of (−)-Exiguolide, a Potent Anticancer Marine Macrolide	1
Heterocycles Award	1
Development of 5-Trifluoromethylpyrimidine Derivatives as Dual Inhibitors of EGFR and Src for Cancer Therapy	1
Total Synthesis of Natural Products and Medicinal Molecules via Chelation-Controlled Diastereoselective Hydride Reduction of Amino Ketones	1
(7S)-Macaureas A and B, Two Urea Analogues from the Roots of Lepidium meyenii	1
Design, Synthesis, and Biological Activity Analysis of Novel Quinazolinyl Ether Derivatives Containing Piperidinamide Structure	1
Reactivity of 4-Bromoacetyl-1,2,3-triazoles towards Amines and Phenols: Synthesis and Antimicrobial Activity of Novel Heterocycles	1
Synthesis of Benzo[d]pyrrolo[1,2-a]imidazoles by Iminocyclopropane Rearrangement of C-Cyclopropylbenzimidazoles	1
Novel Heteroannulated Chromeno[2,3-b]pyridines and Related Compounds Using 6-Methylchromone-3-carbonitrile	1
The Xanthate Route to Benzazepinones and Their Aza Congeners	1
Antimicrobial Activities of Heliciopsis terminalis Trunk Extract	1
Synthesis and Characterization of 6-Chloro-N-(substituted benzylidene)benzothiazol-2-amine by Microwave Irradiation	1
L-Malic Acid as Chiral Auxiliary and Building Block in the Asymmetric Synthesis of (S)-(−)-Crispine A	1
Ruthenium(II)-Catalyzed ortho Hydroxymethylation of 6-Arylpurines with Paraformaldehyde via Purine-Directed C-H Activation	1
New Reactions of Indoline-2-thiones and Aryl Aldehydes: Microwave-Induced One Step Synthesis of Structurally Diverse Thiopyrano-Diindoles	1
An Efficient Synthesis of (Aryl)(4-(2-(arylethynyl)-phenyl)-1H-pyrrol-3-yl)methanone from the Reaction of (E)-1-Aryl-3-(2-(arylethynyl)phenyl)prop-2-en-1-one and p-Toluenesulfonylmethyl Isocyanide	1