OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Ethnopharmacology is 60. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Ligustrazine mitigates chronic venous disease-induced pain hyperalgesia through desensitization of inflammation-associated TRPA1 activity in DRG	837
Acori Tatarinowii Rhizoma-Curcumae Radix Herbal pair ameliorates depression by regulating microglia M1/M2 polarization via TLR4/MyD88/NF-κB pathway	310
Naringin promotes hair regeneration via wnt/β-catenin pathway: A dose-dependent study in C57BL/6J mice	218
Efficacy and safety of Shenqi Dihuang decoction for lupus nephritis: A systematic review and meta-analysis	183
Tianlong kechuanling ameliorated COPD-PH through DNMT3A-GSDMD axis-dependent regulation of endothelial cell pyroptosis	180
Aloperine exerts anti-ovarian cancer effects by regulating the tricarboxylic acid cycle and glycolysis: A comprehensive study integrating network pharmacology, molecular docking, metabolomics, and exp	134
Evaluating the toxicity of the roots of Asarum heterotropoides var. mandshuricum extracted using the decoction method: Genotoxicity, single-dose toxicity, and 13-week repeated-dose toxicity studies	130
Total flavonoids isolated from Fructus Mume (Prunus mume Sieb. et Zucc.) mitigate Parkinson's disease progression by promoting neuronal mitophagy via activation of the CaMKKβ/AMPK signaling pathway	129
Phytochemical profiling and anti-inflammatory activity of Gentiana lutea roots from Pollino National Park	128
YuPingFengSan ameliorates LPS-induced acute lung injury and gut barrier dysfunction in mice	118
Cyathulae radix: A comprehensive review of botany, ethnopharmacology, phytochemistry, pharmacological effects, pharmacokinetics, safety and toxicity, processing methods, analysis methods, and quality	111
Network pharmacology integrated with experimental validation revealed potential molecular mechanisms of Camellia nitidissima C. W. Chi in the treatment of lung cancer	110
Potential therapeutic effects of Chinese herbal medicine in postpartum depression: Mechanisms and future directions	106
Decipher the pharmacological mechanisms of raw and wine-processed Curculigo orchioides Gaertn. on bone destruction in rheumatoid arthritis rats using metabolomics	106
Therapeutic effect of the total saponin from Panax Japonicus on experimental autoimmune encephalomyelitis by attenuating inflammation and regulating gut microbiota in mice	105
Diabetes mellitus and Alzheimer's disease: Understanding disease mechanisms, their correlation, and promising dual activity of selected herbs	104
In vitro and in vivo studies of the therapeutic potential of Tinospora crispa extracts in osteoarthritis: Targeting oxidation, inflammation, and chondroprotection	99
Marsdenia tenacissima (Roxb.) Moon injection exerts a potential anti-tumor effect in prostate cancer through inhibiting ErbB2-GSK3β-HIF1α signaling axis	98
Multi-omics and chemical profiling approaches to understand the material foundation and pharmacological mechanism of sophorae tonkinensis radix et rhizome-induced liver injury in mice	97
Shen-Ling-Bai-Zhu-San alleviates Crohn's disease-like colitis by modulating fatty acid degradation via the peroxisome proliferation-activated receptor pathway: An integrated approach combining network	87
Angong Niuhuang Pill pretreatment alleviates cerebral ischemia-reperfusion injury by inhibiting excessive autophagy through the SIRT1-H4K16ac axis	86
The interaction of alkaloids in Coptis chinensis Franch -Tetradium ruticarpum (A. Juss.) T.G. Hartley with hOCT1 and hOCT2	85
Research progress in the treatment of schistosomiasis with traditional Chinese medicine	85
Miao medicine Gu Yan Xiao tincture inhibits mTOR to stimulate chondrocyte autophagy in a rabbit model of osteoarthritis	83
Mechanism of Huanglian Zhimu Decoction in improving hepatic lipid deposition in type 2 diabetes based on lipidomics and transcriptomics	81

Anti-inflammatory and non-toxic effects of Doyerea emetocathartica aqueous extract in mice	81
The safety evaluation of Shenze Shugan capsule and mechanism of apoptosis induced by five potentially nephrotoxic components	79
Corrigendum to “Modified Dingchuan Decoction treats cough-variant asthma by suppressing lung inflammation and regulating the lung microbiota” [J. Ethnopharmacol. 306 (2023) 116171]	78
Corrigendum to “Discovery of the active compounds of Smilacis Glabrae Rhizoma by utilizing the relationship between the individual differences in blood drug concentration and the pharmacological effec	78
Corrigendum to “Icariin improves learning and memory function in Aβ1-42-induced AD mice through regulation of the BDNF-TrκB signaling pathway”[J. Ethnopharmacol. 318 (2024) 117029]	78
Corrigendum to “Antidepressant effects of Parishin C in chronic social defeat stress-induced depressive mice” [J. Ethnopharmacol. 325 (2024) 117891]	77
Corrigendum to “Integrating serum pharmacochemistry, network pharmacology, and metabolomics to elucidate the detoxification and effect-adjusting mechanism of Chebulae Fructus-processing on Mongolian m	76
Desmodium caudatum (Thunb.) DC. extract attenuates hyperuricemia-induced renal fibrosis via modulating TGF-β1 pathway and uric acid transporters: Evidence from in vitro and in vivo studies	75
Metabolomics reveals the role of PPARα in Tripterygium Wilfordii-induced liver injury	74
Research progress of natural medicine Astragalus mongholicus Bunge in treatment of myocardial fibrosis	74
Maternal-fetal toxicity of Strychnos pseudoquina extract treatment during pregnancy	74
Potential shared therapeutic and hepatotoxic mechanisms of Tripterygium wilfordii polyglycosides treating three kinds of autoimmune skin diseases by regulating IL-17 signaling pathway and Th17 cell di	73
Integrated in vitro - in vivo evaluation of Angelica sinensis essential oil as an anti-acne agent: Mechanistic insights into bioactive compounds and multi-target therapeutic actions	73
Integrated serum pharmacochemistry with network pharmacology and pharmacological validation to elucidate the mechanism of yiqitongmai decoction (YQTMD) against myocardial infarction	72
Shaoyao-Gancao-Tang regulates the T-helper-type 1/T-helper-type 2 ratio in the lung and gut and alters gut microbiota in rats with ovalbumin-induced asthma	71
Confirmation of pain-related neuromodulation mechanism of Bushen Zhuangjin Decoction on knee osteoarthritis	70
Banxia Houpo Decoction reduces lysosomal leakage of prefrontal astrocytes through the OGT-CTSB-NLRP3 pathway to improve depressive-like behaviors	70
Antrodia cinnamomea and its compound dehydroeburicoic acid attenuate nonalcoholic fatty liver disease by upregulating ALDH2 activity	68
Corrigendum to ‘Research progress on the regulation of interstitial cell of Cajal autophagy and apoptosis crosstalk by traditional Chinese medicine in gastrointestinal motility disorders’[J. Ethnophar	67
Xiaozhi formula attenuates non-alcoholic fatty liver disease by regulating lipid metabolism via activation of AMPK and PPAR pathways	67
Shaoyao Gancao decoction alleviates the central hyperalgesia of recurrent NTG-induced migraine in rats by regulating the NGF/TRPV1/COX-2 signal pathway	66
Efficacy and safety of the Chinese herbal medicine Xiao-qing-long-tang for allergic rhinitis: A systematic review and meta-analysis of randomized controlled trials	66
A review of the ethnopharmacology, phytochemistry, pharmacology and toxicology of Fructus Gardeniae (Zhi-zi)	66
Xin-Zi-Sheng-Wan decoction alleviates hyperuricemia-induced renal injury by modulating SPP1-CD44-mediated macrophage infiltration and SRC/FAK/β-catenin signaling pathway	65
Protease inhibitor from Libidibia ferrea seeds attenuates inflammatory and nociceptive responses in mice	64
In vitro and in vivo evaluation of the anti-infective potential of the essential oil extracted from the leaves of Plectranthus amboinicus (lour.) spreng against Klebsiella pneumoniae and elucidation o	63
Loquat (Eriobotrya japonica (Thunb) Lindl.): Evaluation of nutritional value, polyphenol composition, antidiabetic effect, and toxicity of leaf aqueous extract	63
The Protective Effects and Material Basis of Astragalus membranaceus in the Prevention and Treatment of Radiation-Induced Lung Injury via Modulation of the Keap1-Nrf2 Signaling Pathway	62
Integration of metabolomics and transcriptomics reveals that Da Chuanxiong Formula improves vascular cognitive impairment via ACSL4/GPX4 mediated ferroptosis	62
Ginsenoside Rg1 attenuates lipopolysaccharide-induced chronic liver damage by activating Nrf2 signaling and inhibiting inflammasomes in hepatic cells	62
Bamboo leaf: A review of traditional medicinal property, phytochemistry, pharmacology, and purification technology	61
Overcoming multi drug resistance mediated by ABC transporters by a novel acetogenin- annonacin from Annona muricata L.	61
Protective effects of Hawk Tea aqueous extract against copper sulfate-induced oxidative damage in zebrafish model	60
Regulation of optimized new Shengmai powder on cardiomyocyte apoptosis and ferroptosis in ischemic heart failure rats: The mediating role of phosphatidylinositol-3-kinase/protein kinase B/tumor protei	60
YiMu-QingGong san alleviates lipopolysaccharide-induced endometritis in mice via inhibiting inflammation and oxidative stress through regulating macrophage polarization	60
Ginkgolide C attenuates cerebral ischemia/reperfusion-induced inflammatory impairments by suppressing CD40/NF-κB pathway	60