Toxicology Letters

Article	Citations
Repeated-oral dose toxicity of polyethylene microplastics and the possible implications on reproduction and development of the next generation	124
Pesticides, cognitive functions and dementia: A review	91
Adverse health effects of 5G mobile networking technology under real-life conditions	77
Urinary 8-isoprostane as a biomarker for oxidative stress. A systematic review and meta-analysis	46
Low doses of individual and combined deoxynivalenol and zearalenone in naturally moldy diets impair intestinal functions via inducing inflammation and disrupting epithelial barrier in the intestine of	43
Arsenite-induced transgenerational glycometabolism is associated with up-regulation of H3K4me2 via inhibiting spr-5 in caenorhabditis elegans	43
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice	43
Indole microbial intestinal metabolites expand the repertoire of ligands and agonists of the human pregnane X receptor	42
Systemic toxicity eliciting metal ion levels from metallic implants and orthopedic devices – A mini review	41
Carbon monoxide – beyond toxicity?	40
Endoplasmic reticulum stress, an important factor in the development of Parkinson’s disease	40
Classification, hepatotoxic mechanisms, and targets of the risk ingredients in traditional Chinese medicine-induced liver injury	37
Arsenic-induced autophagic alterations and mitochondrial impairments in HPG-S axis of mature male mice offspring (F1-generation): A persistent toxicity study	37
Metabolism and pharmacokinetics of pharmaceuticals in cats (Felix sylvestris catus) and implications for the risk assessment of feed additives and contaminants	36
Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice	35
The influence of air pollution on respiratory microbiome: A link to respiratory disease	34
Ambient PM2.5 chronic exposure leads to cognitive decline in mice: From pulmonary to neuronal inflammation	34
Metabolomics describes previously unknown toxicity mechanisms of isoniazid and rifampicin	34
Cadmium exposure activates NADPH oxidase, renin–angiotensin system and cyclooxygenase 2 pathways in arteries, inducing hypertension and vascular damage	31
Poly (ADP-Ribose) polymerase-1 (PARP-1) overactivity plays a pathogenic role in bile acids-induced nephrotoxicity in cholestatic rats	31
Sevoflurane increases intracellular calcium to induce mitochondrial injury and neuroapoptosis	30
Colchicine increases intestinal permeability, suppresses inflammatory responses, and alters gut microbiota in mice	30
Cadmium and breast cancer – Current state and research gaps in the underlying mechanisms	30
Predicting the reproductive toxicity of chemicals using ensemble learning methods and molecular fingerprints	29
Recent advances in understanding the mechanisms of PM2.5-mediated neurodegenerative diseases	29

The inhibition of NFкB signaling and inflammatory response as a strategy for blunting bile acid-induced hepatic and renal toxicity	28
Transfer of pathological α-synuclein from neurons to astrocytes via exosomes causes inflammatory responses after METH exposure	28
Preclinical safety profile of disitamab vedotin：a novel anti-HER2 antibody conjugated with MMAE	27
Human variability in glutathione-S-transferase activities, tissue distribution and major polymorphic variants: Meta-analysis and implication for chemical risk assessment	27
Nrf2 activation protects auditory hair cells from cisplatin-induced ototoxicity independent on mitochondrial ROS production	27
Effect of PFOA on DNA Methylation and Alternative Splicing in Mouse Liver	26
Drp1, a potential therapeutic target for Parkinson’s disease, is involved in olfactory bulb pathological alteration in the Rotenone-induced rat model	26
Oxidative stress, glutathione, and gene expression as key indicators in SH-SY5Y cells exposed to zearalenone metabolites and beauvericin	25
Urinary biomonitoring of subjects with different smoking habits. Part I: Profiling mercapturic acids	25
Repeated radon exposure induced lung injury and epithelial–mesenchymal transition through the PI3K/AKT/mTOR pathway in human bronchial epithelial cells and mice	25
Methamphetamine induced neuroinflammation in mouse brain and microglial cell line BV2: Roles of the TLR4/TRIF/Peli1 signaling axis	24
CircRNA_0026344 via exosomal miR-21 regulation of Smad7 is involved in aberrant cross-talk of epithelium-fibroblasts during cigarette smoke-induced pulmonary fibrosis	24
Paraquat induces pulmonary fibrosis through Wnt/β-catenin signaling pathway and myofibroblast differentiation	24
Ocular toxicity of mustard gas: A concise review	24
Developmental toxicity caused by sanguinarine in zebrafish embryos via regulating oxidative stress, apoptosis and wnt pathways	24
Quantitative elucidation of maternal-to-fetal transfer of neonicotinoid pesticide clothianidin and its metabolites in mice	24
Induction of lipid droplets in THP-1 macrophages by multi-walled carbon nanotubes in a diameter-dependent manner: A transcriptomic study	23
Assessment of occupational exposure to stainless steel welding fumes – A human biomonitoring study	23
Plasticizer exposure of infants during cardiac surgery	23
Evaluating the effect of ozone in UV induced skin damage	23
International landscape of limits and recommendations for occupational exposure to engineered nanomaterials	22
Prediction of hERG potassium channel blockage using ensemble learning methods and molecular fingerprints	21
Assessment of children’s exposure to currently used pesticides in wallonia, Belgium	21
Cortex dictamni-induced liver injury in mice: The role of P450-mediated metabolic activation of furanoids	21
Pod-based menthol and tobacco flavored e-cigarettes cause mitochondrial dysfunction in lung epithelial cells	21
ZEA-induced autophagy in TM4 cells was mediated by the release of Ca2+ activates CaMKKβ-AMPK signaling pathway in the endoplasmic reticulum	21
Evaluation of the epigenetic alterations and gene expression levels of HepG2 cells exposed to zearalenone and α-zearalenol	21
Lead exposure induces metabolic reprogramming in rat models	20
Anticoagulant activity of black snake (Elapidae: Pseudechis) venoms: Mechanisms, potency, and antivenom efficacy	20
Roxadustat attenuates experimental pulmonary fibrosis in vitro and in vivo	20
Acrylamide induces ferroptosis in HSC-T6 cells by causing antioxidant imbalance of the XCT-GSH-GPX4 signaling and mitochondrial dysfunction	20
Inhibition of NLRP3 inflammasome by glibenclamide attenuated dopaminergic neurodegeneration and motor deficits in paraquat and maneb-induced mouse Parkinson’s disease model	20
Non-occupational exposure to phthalates in Finland	20
Aconitine induces mitochondrial energy metabolism dysfunction through inhibition of AMPK signaling and interference with mitochondrial dynamics in SH-SY5Y cells	20
NIX compensates lost role of parkin in cd-induced mitophagy in HeLa cells through phosphorylation	19
The long persistence of pyrrolizidine alkaloid-derived pyrrole-protein adducts in vivo: Kinetic study following multiple exposures of a pyrrolizidine alkaloid containing extract of Gynura japonica	19
Autophagy-dependent ferroptosis contributes to cisplatin-induced hearing loss	19
Changes and relationship of N6-methyladenosine modification and long non-coding RNAs in oxidative damage induced by cadmium in pancreatic β-cells	19
Differential activation of human pregnane X receptor PXR by isomeric mono-methylated indoles in intestinal and hepatic in vitro models	19
Urban particulate matter regulates tight junction proteins by inducing oxidative stress via the Akt signal pathway in human nasal epithelial cells	19
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells	18
P2X7R orchestrates the progression of murine hepatic fibrosis by making a feedback loop from macrophage to hepatic stellate cells	18
DNA damage signaling in the cellular responses to mustard vesicants	18
Comparative toxicity and liver transcriptomics of legacy and emerging brominated flame retardants following 5-day exposure in the rat	18
In vivo and in vitro α-amanitin metabolism studies using molecular networking	18
Toxic metal (Cd, Hg, Mn, Pb) partition in the maternal/foetal unit: A systematic mini — review of recent epidemiological studies	17
In vivo treatment with varespladib, a phospholipase A2 inhibitor, prevents the peripheral neurotoxicity and systemic disorders induced by Micrurus corallinus (coral snake) venom in rats	17
Toxic consequences and oxidative protein carbonylation from chloropicrin exposure in human corneal epithelial cells	17
Zinc oxide nanoparticle causes toxicity to the development of mouse oocyte and early embryo	17
Dose-dependent emergence of acute and recurrent corneal lesions in sulfur mustard-exposed rabbit eyes	17

High‐refined carbohydrate diet leads to polycystic ovary syndrome-like features and reduced ovarian reserve in female rats	17
LncRNA PCA3 promotes antimony-induced lipid metabolic disorder in prostate cancer by targeting MIR-132-3 P/SREBP1 signaling	17
The genotoxicity potential of luteolin is enhanced by CYP1A1 and CYP1A2 in human lymphoblastoid TK6 cells	17
Glibenclamide attenuates 2,5-hexanedione-induced neurotoxicity in the spinal cord of rats through mitigation of NLRP3 inflammasome activation, neuroinflammation and oxidative stress	17
MircoRNA-143-3p regulating ARL6 is involved in the cadmium-induced inhibition of osteogenic differentiation in human bone marrow mesenchymal stem cells	17
Zearalenone exposure triggered porcine granulosa cells apoptosis via microRNAs-mediated focal adhesion pathway	17
Disruption of normal adipocyte development and function by methyl- and propyl- paraben exposure	16
Hepatoxicity mechanism of cantharidin-induced liver LO2 cells by LC–MS metabolomics combined traditional approaches	16
Cadmium induces iron deficiency anemia through the suppression of iron transport in the duodenum	16
Chloropicrin-induced toxicity in the respiratory system	16
The ameliorative effect of niclosamide on bile duct ligation induced liver fibrosis via suppression of NOTCH and Wnt pathways	16
AhR-mediated CYP1A1 and ROS overexpression are involved in hepatotoxicity of decabromodiphenyl ether (BDE-209)	16
iTRAQ-based quantitative proteomics analysis of Sprague-Dawley rats liver reveals perfluorooctanoic acid-induced lipid metabolism and urea cycle dysfunction	16
Arsenite-induced downregulation of occludin in mouse lungs and BEAS-2B cells via the ROS/ERK/ELK1/MLCK and ROS/p38 MAPK signaling pathways	16
ATF4-mediated autophagy-dependent glycolysis plays an important role in attenuating apoptosis induced by Cr (VI) in A549 cells	16
Novel approach for the detection of alkylated bases using the enzyme-modified comet assay	16
Up-regulation of DNMT3b contributes to HOTAIRM1 silencing via DNA hypermethylation in cells transformed by long-term exposure to hydroquinone and workers exposed to benzene	16
Clinical implications of differential procoagulant toxicity of the palearctic viperid genus Macrovipera, and the relative neutralization efficacy of antivenoms and enzyme inhibitors	16
The mycotoxin beauvericin impairs development, fertility and life span in the nematode Caenorhabditis elegans accompanied by increased germ cell apoptosis and lipofuscin accumulation	15
Overexpression of endogenous lipoic acid synthase attenuates pulmonary fibrosis induced by crystalline silica in mice	15
Short-term exposure of decabromodiphenyl ether in female adult Balb/c mice: Immune toxicity and self-recovery	15
Airway basal cell injury after acute diacetyl (2,3-butanedione) vapor exposure	15
Differential susceptibility of rat primary neurons and neural stem cells to PFOS and PFOA toxicity	15
Mass spectrometry imaging reveals lipid upregulation and bile acid changes indicating amitriptyline induced steatosis in a rat model	15
The development of an in vitro 3D model of goblet cell hyperplasia using MUC5AC expression and repeated whole aerosol exposures	15
Aging-related changes in the sensitivity of behavioral effects of the neonicotinoid pesticide clothianidin in male mice	15
Internal exposure of firefighting instructors to polycyclic aromatic hydrocarbons (PAH) during live fire training	15
Generation of pro-and anti-inflammatory mediators after acetaminophen overdose in surviving and non-surviving patients	14
Anticoagulant Micrurus venoms: Targets and neutralization	14
Human Variability in Carboxylesterases and carboxylesterase-related Uncertainty Factors for Chemical Risk Assessment	14
Transcriptome profile analysis reveals a silica-induced immune response and fibrosis in a silicosis rat model	14
Depletion of serotonin relieves concanavalin A-induced liver fibrosis in mice by inhibiting inflammation, oxidative stress, and TGF-β1/Smads signaling pathway	14
Fumonisin B1 triggers the formation of bovine neutrophil extracellular traps	14
Regulation of the SIRT1 signaling pathway in NMDA-induced Excitotoxicity	14
Triptolide and atorvastatin synergistically promote hepatotoxicity in cultured hepatocytes and female Sprague-Dawley rats by inhibiting pregnane X receptor-mediated transcriptional activation of CYP3A	14
Manganese induced nervous injury by α-synuclein accumulation via ATP-sensitive K(+) channels and GABA receptors	14
Doxorubicin induces arterial stiffness: A comprehensive in vivo and ex vivo evaluation of vascular toxicity in mice	14
Environmental factors in Parkinson’s disease: New insights into the molecular mechanisms	13
Reactive oxygen species production by BP-1,6-quinone and its effects on the endothelial dysfunction: Involvement of the mitochondria	13
Immunotoxicity and uterine transcriptome analysis of the effect of zearalenone (ZEA) in sows during the embryo attachment period	13
Effects of oral exposure to arsenite on arsenic metabolism and transport in rat kidney	13
Autophagy mediates bronchial cell malignant transformation induced by chronic arsenic exposure via MEK/ERK1/2 pathway	13
Pharmacokinetics of Three Oximes in a Guinea Pig Model and Efficacy of Combined Oxime Therapy	13
Reference ranges of oxidative stress biomarkers selected for non-invasive biological surveillance of nanotechnology workers: Study protocol and meta-analysis results for 8-OHdG in exhaled breath conde	13
Shp2 regulates PM2.5-induced airway epithelial barrier dysfunction by modulating ERK1/2 signaling pathway	13
Copper exposure disrupts ovarian steroidogenesis in human ovarian granulosa cells via the FSHR/CYP19A1 pathway and alters methylation patterns on the SF-1 gene promoter	13
Soluble silver ions from silver nanoparticles induce a polarised secretion of interleukin-8 in differentiated Caco-2 cells	13
The potential diagnostic and therapeutic applications of exosomes in drug-induced liver injury	13
Regulation of CRMP2 by Cdk5 and GSK-3β participates in sevoflurane-induced dendritic development abnormalities and cognitive dysfunction in developing rats	13
Early molecular events associated with liver and colon sub-acute responses to 1,2-dimethylhydrazine: Potential implications on preneoplastic and neoplastic lesion development	13
The disruption and hyperpermeability of blood-labyrinth barrier mediates cisplatin-induced ototoxicity	13
Cadmium causes hepatopathy by changing the status of DNA methylation in the metabolic pathway	13
Exposure to harmful and potentially harmful constituents decreased in smokers switching to Carbon-Heated Tobacco Product	13
Modulation of NAD+ biosynthesis activates SIRT1 and resists cisplatin-induced ototoxicity	13
Dual role of cadmium in rat liver: Inducing liver injury and inhibiting the progression of early liver cancer	12
Differences in teratogenicity of some vitamin K antagonist substances used as human therapeutic or rodenticide are due to major differences in their fate after an oral administration	12
In vitro detoxication of microcystins in human samples: variability among variants with different hydrophilicity and structure	12
Modes of action considerations in threshold expectations for health effects of benzene	12
α-asarone induces cardiac defects and QT prolongation through mitochondrial apoptosis pathway in zebrafish	12
Buccal micronucleus cytome assay: Inter-laboratory scoring exercise and micronucleus and nuclear abnormalities frequencies in different populations from Brazil	12
Glutathione is a potential therapeutic target for acrolein toxicity in the cornea	12
Melamine impairs working memory and reduces prefrontal activity associated with inhibition of AMPA receptor GluR2/3 subunit expression	12
In vivo and in vitro inflammatory responses to fine particulate matter (PM2.5) from China and California	12
Benchmark dose analyses of toxic endpoints in lung cells provide sensitivity and toxicity ranking across metal oxide nanoparticles and give insights into the mode of action	12
JUUL e-liquid exposure elicits cytoplasmic Ca2+ responses and leads to cytotoxicity in cultured airway epithelial cells	12
Mechanism of hepatotoxicity of first-line tyrosine kinase inhibitors: Gefitinib and afatinib	12
The neuroprotective effect of oxytocin on vincristine-induced neurotoxicity in mice	12
A suitable silicosis mouse model was constructed by repeated inhalation of silica dust via nose	12
Extended regorafenib treatment can be linked with mitochondrial damage leading to cardiotoxicity	12
Biomonitoring of the benzene metabolite s-phenylmercapturic acid and the toluene metabolite s-benzylmercapturic acid in urine from firefighters	12
Assessment of the absorbed dose after exposure to surgical smoke in an operating room	12
Glycochenodeoxycholic acid impairs transcription factor E3 -dependent autophagy-lysosome machinery by disrupting reactive oxygen species homeostasis in L02 cells	11
Perinatal exposure to the thyroperoxidase inhibitors methimazole and amitrole perturbs thyroid hormone system signaling and alters motor activity in rat offspring	11
Paraquat mediates BV-2 microglia activation by raising intracellular ROS and inhibiting Akt1 phosphorylation	11
Therapeutic measures for sulfur mustard-induced ocular injury	11
Dechlorination and demethylation of ochratoxin A enhance blocking activity of PXR activation, suppress PXR expression and reduce cytotoxicity	11
Effect of combustion-derived particles on genotoxicity and telomere length: A study on human cells and exposed populations	11
Meloxicam methyl group determines enzyme specificity for thiazole bioactivation compared to sudoxicam	11
Glucocorticoid-insulin-like growth factor 1 (GC-IGF1) axis programming mediated hepatic lipid-metabolic in offspring caused by prenatal ethanol exposure	11
A versatile toxicity evaluation of ethyl carbamate (urethane) on zebrafish embryos: Morphological, physiological, histopathological, immunohistochemical, transcriptional and behavioral approaches	11

Possible role of n-hexane as an endocrine disruptor in occupationally exposed women at reproductive age	11
Exploration study on serum metabolic profiles of Chinese male patients with artificial stone silicosis, silicosis, and coal worker's pneumoconiosis	11
Optimization of aqueous aerosol extract (AqE) generation from e-cigarettes and tobacco heating products for in vitro cytotoxicity testing	11
Downregulation of vdac2 inhibits spermatogenesis via JNK and P53 signalling in mice exposed to cadmium	11
In vivo toxicity assessment of four types of graphene quantum dots (GQDs) using mRNA sequencing	11
Trimeresurus albolabris snakebite treatment implications arising from ontogenetic venom comparisons of anticoagulant function, and antivenom efficacy	11
Harmful chemicals of heat not burn product and its induced oxidative stress of macrophages at air-liquid interface: Comparison with ultra-light cigarette	11
Energy disorders caused by mitochondrial dysfunction contribute to α-amatoxin-induced liver function damage and liver failure	11
The unreliability of the reliability criteria in the estimation of QSAR for skin sensitivity: A pun or a reliable law?	11
MicroRNA-195-3p promotes hepatic stellate cell activation and liver fibrosis by suppressing PTEN expression	11
An in vitro study on the transport and phase II metabolism of the mycotoxin alternariol in combination with the structurally related gut microbial metabolite urolithin C	11
Comparative genotoxic potential of 27 polycyclic aromatic hydrocarbons in three human cell lines	11
Impaired activation of Notch-1 signaling hinders repair processes of bronchial epithelial cells exposed to cigarette smoke	11
1,2-Dichloroethane induces cerebellum granular cell apoptosis via mitochondrial pathway in vitro and in vivo	11
Effect of PM10 on pulmonary immune response and fetus development	11
Sphingosine 1-phosphate receptor-1 specific agonist SEW2871 ameliorates ANIT-induced dysregulation of bile acid homeostasis in mice plasma and liver	11
Frailty syndrome, biomarkers and environmental factors – A pilot study	10
Metabolism of glyphosate by the human fecal microbiota	10
Human phase I in vitro liver metabolism of two bisphenolic diglycidyl ethers BADGE and BFDGE	10
Alpha-lipoic acid attenuates silica-induced pulmonary fibrosis by improving mitochondrial function via AMPK/PGC1α pathway activation in C57BL/6J mice	10
Vitamin D3 protects against nitrogen mustard-induced apoptosis of the bronchial epithelial cells via activating the VDR/Nrf2/Sirt3 pathway	10
Ochratoxin A induces reprogramming of glucose metabolism by switching energy metabolism from oxidative phosphorylation to glycolysis in human gastric epithelium GES-1 cells in vitro	10
Chronic cadmium exposure induces epithelial mesenchymal transition in prostate cancer cells through a TGF-β-independent, endoplasmic reticulum stress induced pathway	10
Exposure to traffic-generated air pollution promotes alterations in the integrity of the brain microvasculature and inflammation in female ApoE-/- mice	10
Evaluation of a high-throughput in vitro endothelial cell migration assay for the assessment of nicotine and tobacco delivery products	10
TP53-induced glycolysis and apoptosis regulator (TIGAR) ameliorates lysosomal damage in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-mediated mouse model of Parkinson’s disease	10
Repression of mercury accumulation and adverse effects of methylmercury exposure is mediated by cystathionine γ-lyase to produce reactive sulfur species in mouse brain	10
Grouping of phthalates for risk characterization of human exposures	10
Enhanced mitophagy mediated by the YAP/Parkin pathway protects against DOX-induced cardiotoxicity	10
Microcystin-LR impairs glucose metabolism in pancreatic β cells in vivo and in vitro	10
Subchronic exposure to acrylamide caused behaviour disorders and related pathological and molecular changes in rat cerebellum	10
Urinary biomonitoring of subjects with different smoking habits. Part II: an untargeted metabolomic approach and the comparison with the targeted measurement of mercapturic acids	10
Background contamination of perfluoralkyl substances in a Belgian general population	10
LncRNA Meg3-mediated regulation of the Smad pathway in atRA-induced cleft palate	10
CypD deficiency confers neuroprotection against mitochondrial abnormality caused by lead in SH-SY5Y cell	10
Advances in sulfur mustard-induced DNA adducts: Characterization and detection	10
Refinement of health-based guidance values for cadmium in the French population based on modelling	10
Systematic comparison of the male reproductive tract in fetal and adult Wistar rats exposed to DBP and DINP in utero during the masculinisation programming window	10
Towards a recommended biomonitoring strategy for assessing the occupational exposure of roofers to PAHs	10
Differential coagulotoxicity of metalloprotease isoforms from Bothrops neuwiedi snake venom and consequent variations in antivenom efficacy	10
The dual role of immune response in acetaminophen hepatotoxicity: Implication for immune pharmacological targets	10
Myricetin and M10, a myricetin-3-O-β-d-lactose sodium salt, modify composition of gut microbiota in mice with ulcerative colitis	10
NAD+ in sulfur mustard toxicity	10
Differential response of human T-lymphocytes to arsenic and uranium	10
Suppression of Th2 cytokines as a potential mechanism for reduced antibody response following PFOA exposure in female B6C3F1 mice	10
Clinical implications of ontogenetic differences in the coagulotoxic activity of Bothrops jararacussu venoms	10
A lncRNA Gpr137b-ps/miR-200a-3p/CXCL14 axis modulates hepatic stellate cell (HSC) activation	9
Are pigs a suitable animal model for in vivo metabolism studies of new psychoactive substances? A comparison study using different in vitro/in vivo tools and U-47700 as model drug	9
N-acetyl cysteine protects against chlorine-induced tissue damage in an ex vivo model	9
Tributyltin and triphenyltin induce 11β-hydroxysteroid dehydrogenase 2 expression and activity through activation of retinoid X receptor α	9
Tissue-specific expression and activity of cytochrome P450 1A and 3A in rainbow trout (Oncorhynchus mykiss)	9
Paternal nicotine exposure promotes hepatic fibrosis in offspring	9
Local renal complement activation mediates immune kidney injury by inducing endothelin-1 signalling and inflammation in trichloroethylene-sensitised mice	9
Getting stoned: Characterisation of the coagulotoxic and neurotoxic effects of reef stonefish (Synanceia verrucosa) venom	9
Effects of prenatal chlorocholine chloride exposure on pubertal development and reproduction of male offspring in rats	9
Interactions of bisphenol diglycidyl ethers with estrogen receptors α: Fluorescence polarization, reporter gene, and molecular modeling investigations	9
Effects of Ochratoxin A exposure on DNA damage in porcine granulosa cells in vitro	9
Exploration of zebrafish larvae as an alternative whole-animal model for nephrotoxicity testing	9
Platelets prevent the development of monocrotaline-induced liver injury in mice	9
Cigarette Smoke Extract induces H19 in Esophageal Squamous Cell Carcinoma in Smoking Patients: Based on A Chronic Exposed Cell Model	9
Arsenic disrupts neuronal insulin signaling through increasing free PI3K-p85 and decreasing PI3K activity	9
PPARγ mediates the anti-pulmonary fibrosis effect of icaritin	9
Transfer of α-synuclein from neurons to oligodendrocytes triggers myelin sheath destruction in methamphetamine administration mice	9
Bioactivation of trichloroethylene to three regioisomeric glutathione conjugates by liver fractions and recombinant human glutathione transferases: Species differences and implications for human risk	9
High-mobility group box 1 promotes epithelial-to-mesenchymal transition in crystalline silica induced pulmonary inflammation and fibrosis	9
Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling	9
Tumorigenic response in lung tumor susceptible A/J mice after sub-chronic exposure to calcium chromate or iron (III) oxide	9
The main mechanisms of trimethyltin chloride-induced neurotoxicity: Energy metabolism disorder and peroxidation damage	8
Application of HepG2/C3A liver spheroids as a model system for genotoxicity studies	8
FBXO22, ubiquitination degradation of PHLPP1, ameliorates rotenone induced neurotoxicity by activating AKT pathway	8
Mechanism of LncRNA XIST/ miR-101–3p/ZEB1 axis in EMT associated with silicosis	8
Mechanistic understanding of dendritic cell activation in skin sensitization: additional evidences to support potency classification	8
A human relevant mixture of persistent organic pollutants (POPs) and perfluorooctane sulfonic acid (PFOS) enhance nerve growth factor (NGF)-induced neurite outgrowth in PC12 cells	8
Arsenic exposure impairs intestinal stromal cells	8
Analysis of serum metabolome of workers occupationally exposed to hexavalent chromium: A preliminary study	8
Role of endothelial biomarkers in predicting acute kidney injury in Bothrops envenoming	8
Notch1-mediated histone demethylation of HCN4 contributes to aconitine-induced ventricular myocardial dysrhythmia	8
Targeted and untargeted metabolomics applied to occupational exposure to hyperbaric atmosphere	8
Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR	8
A genome-wide screen for differentially methylated long noncoding RNAs identified that lncAC007255.8 is regulated by promoter DNA methylation in Beas-2B cells malignantly transformed by NNK	8
Monomethylated arsenic was the Major methylated arsenic in Red blood cells of acute promyelocytic leukemia patients treated with arsenic trioxide	8
Sex-specific effects of triphenyltin chloride (TPT) on thyroid disruption and metabolizing enzymes in adult zebrafish (Danio rerio)	8
DNA damage in colon mucosa of Pirc rats, an Apc-driven model of colon tumorigenesis	8
The mouse Anxa6/miR-9-5p/Anxa2 axis modulates TGF-β1-induced mouse hepatic stellate cell (mHSC) activation and CCl4-caused liver fibrosis	8
Investigation of cardiac glycosides from oleander in a human induced pluripotent stem cells derived cardiomyocyte model	8
Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation	8
Acrolein-conjugated proteomics in brains of adult C57BL/6 mice chronically exposed to acrolein and aged APP/PS1 transgenic AD mice	8
3-Monochloropropane-1,2-diol causes spermatogenesis failure in male rats via Sertoli cell dysfunction but not testosterone reduction	8
Genotoxicity of cationic lipopeptide nanoparticles	8
Derivation of an occupational exposure limit for benzene using epidemiological study quality assessment tools	8
Nicotine facilitates pancreatic fibrosis by promoting activation of pancreatic stellate cells via α7nAChR-mediated JAK2/STAT3 signaling pathway in rats	8
High mobility group box-1 protects against Aflatoxin G1-induced pulmonary epithelial cell damage in the lung inflammatory environment	8
The MIR100HG/miR-29a-3p/Tab1 axis modulates TGF-β1-induced fibrotic changes in type II alveolar epithelial cells BLM-caused lung fibrogenesis in mice	8
PXR-mediated expression of FABP4 promotes valproate-induced lipid accumulation in HepG2 cells	8
Methamphetamine mediates apoptosis of vascular smooth muscle cells via the chop-related endoplasmic reticulum stress pathway	8