Toxicology Letters

Papers
(The median citation count of Toxicology Letters is 0. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Repeated-oral dose toxicity of polyethylene microplastics and the possible implications on reproduction and development of the next generation115
Pesticides, cognitive functions and dementia: A review90
Adverse health effects of 5G mobile networking technology under real-life conditions76
Cadmium-induced cytotoxicity in mouse liver cells is associated with the disruption of autophagic flux via inhibiting the fusion of autophagosomes and lysosomes47
Urinary 8-isoprostane as a biomarker for oxidative stress. A systematic review and meta-analysis44
Low doses of individual and combined deoxynivalenol and zearalenone in naturally moldy diets impair intestinal functions via inducing inflammation and disrupting epithelial barrier in the intestine of43
Arsenite-induced transgenerational glycometabolism is associated with up-regulation of H3K4me2 via inhibiting spr-5 in caenorhabditis elegans43
Choking agents and chlorine gas – History, pathophysiology, clinical effects and treatment43
Indole microbial intestinal metabolites expand the repertoire of ligands and agonists of the human pregnane X receptor42
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice40
Endoplasmic reticulum stress, an important factor in the development of Parkinson’s disease39
Systemic toxicity eliciting metal ion levels from metallic implants and orthopedic devices – A mini review39
Carbon monoxide – beyond toxicity?38
Arsenic-induced autophagic alterations and mitochondrial impairments in HPG-S axis of mature male mice offspring (F1-generation): A persistent toxicity study37
Classification, hepatotoxic mechanisms, and targets of the risk ingredients in traditional Chinese medicine-induced liver injury37
Metabolism and pharmacokinetics of pharmaceuticals in cats (Felix sylvestris catus) and implications for the risk assessment of feed additives and contaminants36
Metabolomics describes previously unknown toxicity mechanisms of isoniazid and rifampicin34
The influence of air pollution on respiratory microbiome: A link to respiratory disease34
Ambient PM2.5 chronic exposure leads to cognitive decline in mice: From pulmonary to neuronal inflammation33
Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice33
Recent sulfur mustard attacks in Middle East and experience of health professionals33
Andrographolide ameliorates bleomycin-induced pulmonary fibrosis by suppressing cell proliferation and myofibroblast differentiation of fibroblasts via the TGF-β1-mediated Smad-dependent and -independe31
Poly (ADP-Ribose) polymerase-1 (PARP-1) overactivity plays a pathogenic role in bile acids-induced nephrotoxicity in cholestatic rats31
Hedgehog signaling pathway regulates hexavalent chromium-induced liver fibrosis by activation of hepatic stellate cells31
Cadmium exposure activates NADPH oxidase, renin–angiotensin system and cyclooxygenase 2 pathways in arteries, inducing hypertension and vascular damage31
Cadmium and breast cancer – Current state and research gaps in the underlying mechanisms30
Predicting the reproductive toxicity of chemicals using ensemble learning methods and molecular fingerprints28
Colchicine increases intestinal permeability, suppresses inflammatory responses, and alters gut microbiota in mice28
Recent advances in understanding the mechanisms of PM2.5-mediated neurodegenerative diseases28
Metabolism and urinary excretion kinetics of di(2-ethylhexyl) adipate (DEHA) in four human volunteers after a single oral dose28
Transfer of pathological α-synuclein from neurons to astrocytes via exosomes causes inflammatory responses after METH exposure28
Sevoflurane increases intracellular calcium to induce mitochondrial injury and neuroapoptosis27
The inhibition of NFкB signaling and inflammatory response as a strategy for blunting bile acid-induced hepatic and renal toxicity27
Human variability in glutathione-S-transferase activities, tissue distribution and major polymorphic variants: Meta-analysis and implication for chemical risk assessment26
Drp1, a potential therapeutic target for Parkinson’s disease, is involved in olfactory bulb pathological alteration in the Rotenone-induced rat model26
Urinary biomonitoring of subjects with different smoking habits. Part I: Profiling mercapturic acids25
Effect of PFOA on DNA Methylation and Alternative Splicing in Mouse Liver25
Nrf2 activation protects auditory hair cells from cisplatin-induced ototoxicity independent on mitochondrial ROS production24
Preclinical safety profile of disitamab vedotin:a novel anti-HER2 antibody conjugated with MMAE24
Repeated radon exposure induced lung injury and epithelial–mesenchymal transition through the PI3K/AKT/mTOR pathway in human bronchial epithelial cells and mice24
Oxidative stress, glutathione, and gene expression as key indicators in SH-SY5Y cells exposed to zearalenone metabolites and beauvericin24
Ocular toxicity of mustard gas: A concise review24
Methamphetamine induced neuroinflammation in mouse brain and microglial cell line BV2: Roles of the TLR4/TRIF/Peli1 signaling axis24
Methamphetamine-induced alterations in intestinal mucosal barrier function occur via the microRNA-181c/ TNF-α/tight junction axis23
Evaluating the effect of ozone in UV induced skin damage23
Developmental toxicity caused by sanguinarine in zebrafish embryos via regulating oxidative stress, apoptosis and wnt pathways23
Induction of lipid droplets in THP-1 macrophages by multi-walled carbon nanotubes in a diameter-dependent manner: A transcriptomic study23
Plasticizer exposure of infants during cardiac surgery23
Quantitative elucidation of maternal-to-fetal transfer of neonicotinoid pesticide clothianidin and its metabolites in mice22
Paraquat induces pulmonary fibrosis through Wnt/β-catenin signaling pathway and myofibroblast differentiation22
ZEA-induced autophagy in TM4 cells was mediated by the release of Ca2+ activates CaMKKβ-AMPK signaling pathway in the endoplasmic reticulum21
Cortex dictamni-induced liver injury in mice: The role of P450-mediated metabolic activation of furanoids21
Prediction of hERG potassium channel blockage using ensemble learning methods and molecular fingerprints21
Assessment of children’s exposure to currently used pesticides in wallonia, Belgium21
Benzo(a)pyrene regulated A549 cell migration, invasion and epithelial-mesenchymal transition by up-regulating long non-coding RNA linc0067321
Assessment of occupational exposure to stainless steel welding fumes – A human biomonitoring study21
Acute severe intoxication with cyclopropylfentanyl, a novel synthetic opioid20
Anticoagulant activity of black snake (Elapidae: Pseudechis) venoms: Mechanisms, potency, and antivenom efficacy20
Non-occupational exposure to phthalates in Finland20
Particulate matters induce acute exacerbation of allergic airway inflammation via the TLR2/NF-κB/NLRP3 signaling pathway20
Inhibition of NLRP3 inflammasome by glibenclamide attenuated dopaminergic neurodegeneration and motor deficits in paraquat and maneb-induced mouse Parkinson’s disease model20
Roxadustat attenuates experimental pulmonary fibrosis in vitro and in vivo20
CircRNA_0026344 via exosomal miR-21 regulation of Smad7 is involved in aberrant cross-talk of epithelium-fibroblasts during cigarette smoke-induced pulmonary fibrosis20
Pod-based menthol and tobacco flavored e-cigarettes cause mitochondrial dysfunction in lung epithelial cells20
Changes and relationship of N6-methyladenosine modification and long non-coding RNAs in oxidative damage induced by cadmium in pancreatic β-cells19
Lead exposure induces metabolic reprogramming in rat models19
Aconitine induces mitochondrial energy metabolism dysfunction through inhibition of AMPK signaling and interference with mitochondrial dynamics in SH-SY5Y cells19
Evaluation of the epigenetic alterations and gene expression levels of HepG2 cells exposed to zearalenone and α-zearalenol19
Acrylamide induces ferroptosis in HSC-T6 cells by causing antioxidant imbalance of the XCT-GSH-GPX4 signaling and mitochondrial dysfunction19
NIX compensates lost role of parkin in cd-induced mitophagy in HeLa cells through phosphorylation19
The long persistence of pyrrolizidine alkaloid-derived pyrrole-protein adducts in vivo: Kinetic study following multiple exposures of a pyrrolizidine alkaloid containing extract of Gynura japonica19
International landscape of limits and recommendations for occupational exposure to engineered nanomaterials19
Differential activation of human pregnane X receptor PXR by isomeric mono-methylated indoles in intestinal and hepatic in vitro models19
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells18
DNA damage signaling in the cellular responses to mustard vesicants18
Comparative toxicity and liver transcriptomics of legacy and emerging brominated flame retardants following 5-day exposure in the rat18
Urban particulate matter regulates tight junction proteins by inducing oxidative stress via the Akt signal pathway in human nasal epithelial cells18
Toxic metal (Cd, Hg, Mn, Pb) partition in the maternal/foetal unit: A systematic mini — review of recent epidemiological studies17
In vivo treatment with varespladib, a phospholipase A2 inhibitor, prevents the peripheral neurotoxicity and systemic disorders induced by Micrurus corallinus (coral snake) venom in rats17
Zearalenone exposure triggered porcine granulosa cells apoptosis via microRNAs-mediated focal adhesion pathway17
In vivo and in vitro α-amanitin metabolism studies using molecular networking17
Dose-dependent emergence of acute and recurrent corneal lesions in sulfur mustard-exposed rabbit eyes17
MircoRNA-143-3p regulating ARL6 is involved in the cadmium-induced inhibition of osteogenic differentiation in human bone marrow mesenchymal stem cells17
LncRNA PCA3 promotes antimony-induced lipid metabolic disorder in prostate cancer by targeting MIR-132-3 P/SREBP1 signaling17
P2X7R orchestrates the progression of murine hepatic fibrosis by making a feedback loop from macrophage to hepatic stellate cells17
Glibenclamide attenuates 2,5-hexanedione-induced neurotoxicity in the spinal cord of rats through mitigation of NLRP3 inflammasome activation, neuroinflammation and oxidative stress17
Toxic consequences and oxidative protein carbonylation from chloropicrin exposure in human corneal epithelial cells17
Zinc oxide nanoparticle causes toxicity to the development of mouse oocyte and early embryo17
Clinical implications of differential procoagulant toxicity of the palearctic viperid genus Macrovipera, and the relative neutralization efficacy of antivenoms and enzyme inhibitors16
High‐refined carbohydrate diet leads to polycystic ovary syndrome-like features and reduced ovarian reserve in female rats16
AhR-mediated CYP1A1 and ROS overexpression are involved in hepatotoxicity of decabromodiphenyl ether (BDE-209)16
ATF4-mediated autophagy-dependent glycolysis plays an important role in attenuating apoptosis induced by Cr (VI) in A549 cells16
Application of the fentanyl analog screening kit toward the identification of emerging synthetic opioids in human plasma and urine by LC-QTOF16
Arsenite-induced downregulation of occludin in mouse lungs and BEAS-2B cells via the ROS/ERK/ELK1/MLCK and ROS/p38 MAPK signaling pathways16
Chloropicrin-induced toxicity in the respiratory system16
Up-regulation of DNMT3b contributes to HOTAIRM1 silencing via DNA hypermethylation in cells transformed by long-term exposure to hydroquinone and workers exposed to benzene16
Novel approach for the detection of alkylated bases using the enzyme-modified comet assay16
Hepatoxicity mechanism of cantharidin-induced liver LO2 cells by LC–MS metabolomics combined traditional approaches16
The genotoxicity potential of luteolin is enhanced by CYP1A1 and CYP1A2 in human lymphoblastoid TK6 cells15
The mycotoxin beauvericin impairs development, fertility and life span in the nematode Caenorhabditis elegans accompanied by increased germ cell apoptosis and lipofuscin accumulation15
Transcriptomic analysis reveals the mechanism of sulfasalazine-induced liver injury in mice15
iTRAQ-based quantitative proteomics analysis of Sprague-Dawley rats liver reveals perfluorooctanoic acid-induced lipid metabolism and urea cycle dysfunction15
Autophagy-dependent ferroptosis contributes to cisplatin-induced hearing loss15
The development of an in vitro 3D model of goblet cell hyperplasia using MUC5AC expression and repeated whole aerosol exposures15
Differential susceptibility of rat primary neurons and neural stem cells to PFOS and PFOA toxicity15
Mass spectrometry imaging reveals lipid upregulation and bile acid changes indicating amitriptyline induced steatosis in a rat model15
The ameliorative effect of niclosamide on bile duct ligation induced liver fibrosis via suppression of NOTCH and Wnt pathways15
Cadmium induces iron deficiency anemia through the suppression of iron transport in the duodenum15
Short-term exposure of decabromodiphenyl ether in female adult Balb/c mice: Immune toxicity and self-recovery15
Disruption of normal adipocyte development and function by methyl- and propyl- paraben exposure14
Anticoagulant Micrurus venoms: Targets and neutralization14
Critical role of toll-like receptor 4 (TLR4) in ricin toxin-induced inflammatory responses in macrophages14
Internal exposure of firefighting instructors to polycyclic aromatic hydrocarbons (PAH) during live fire training14
Manganese induced nervous injury by α-synuclein accumulation via ATP-sensitive K(+) channels and GABA receptors14
Regulation of the SIRT1 signaling pathway in NMDA-induced Excitotoxicity14
Aging-related changes in the sensitivity of behavioral effects of the neonicotinoid pesticide clothianidin in male mice14
Transcriptome profile analysis reveals a silica-induced immune response and fibrosis in a silicosis rat model14
Airway basal cell injury after acute diacetyl (2,3-butanedione) vapor exposure14
Fumonisin B1 triggers the formation of bovine neutrophil extracellular traps14
Overexpression of endogenous lipoic acid synthase attenuates pulmonary fibrosis induced by crystalline silica in mice14
Triptolide and atorvastatin synergistically promote hepatotoxicity in cultured hepatocytes and female Sprague-Dawley rats by inhibiting pregnane X receptor-mediated transcriptional activation of CYP3A14
Depletion of serotonin relieves concanavalin A-induced liver fibrosis in mice by inhibiting inflammation, oxidative stress, and TGF-β1/Smads signaling pathway13
Reactive oxygen species production by BP-1,6-quinone and its effects on the endothelial dysfunction: Involvement of the mitochondria13
Effects of oral exposure to arsenite on arsenic metabolism and transport in rat kidney13
Evaluation of high-affinity phenyltetrahydroisoquinoline aldoximes, linked through anti-triazoles, as reactivators of phosphylated cholinesterases13
Generation of pro-and anti-inflammatory mediators after acetaminophen overdose in surviving and non-surviving patients13
Modulation of NAD+ biosynthesis activates SIRT1 and resists cisplatin-induced ototoxicity13
Regulation of CRMP2 by Cdk5 and GSK-3β participates in sevoflurane-induced dendritic development abnormalities and cognitive dysfunction in developing rats13
Immunotoxicity and uterine transcriptome analysis of the effect of zearalenone (ZEA) in sows during the embryo attachment period13
Exposure to harmful and potentially harmful constituents decreased in smokers switching to Carbon-Heated Tobacco Product13
Human Variability in Carboxylesterases and carboxylesterase-related Uncertainty Factors for Chemical Risk Assessment13
The potential diagnostic and therapeutic applications of exosomes in drug-induced liver injury13
Pharmacokinetics of Three Oximes in a Guinea Pig Model and Efficacy of Combined Oxime Therapy13
Early molecular events associated with liver and colon sub-acute responses to 1,2-dimethylhydrazine: Potential implications on preneoplastic and neoplastic lesion development13
Cadmium causes hepatopathy by changing the status of DNA methylation in the metabolic pathway13
Doxorubicin induces arterial stiffness: A comprehensive in vivo and ex vivo evaluation of vascular toxicity in mice13
Autophagy mediates bronchial cell malignant transformation induced by chronic arsenic exposure via MEK/ERK1/2 pathway13
Protein adduct binding properties of tabun-subtype nerve agents after exposure in vitro and in vivo13
The disruption and hyperpermeability of blood-labyrinth barrier mediates cisplatin-induced ototoxicity12
Biomonitoring of the benzene metabolite s-phenylmercapturic acid and the toluene metabolite s-benzylmercapturic acid in urine from firefighters12
Soluble silver ions from silver nanoparticles induce a polarised secretion of interleukin-8 in differentiated Caco-2 cells12
A catalytic bioscavenger with improved stability and reduced susceptibility to oxidation for treatment of acute poisoning with neurotoxic organophosphorus compounds12
In vitro detoxication of microcystins in human samples: variability among variants with different hydrophilicity and structure12
Environmental factors in Parkinson’s disease: New insights into the molecular mechanisms12
Reference ranges of oxidative stress biomarkers selected for non-invasive biological surveillance of nanotechnology workers: Study protocol and meta-analysis results for 8-OHdG in exhaled breath conde12
Benchmark dose analyses of toxic endpoints in lung cells provide sensitivity and toxicity ranking across metal oxide nanoparticles and give insights into the mode of action12
α-asarone induces cardiac defects and QT prolongation through mitochondrial apoptosis pathway in zebrafish12
Assessment of the absorbed dose after exposure to surgical smoke in an operating room12
Melamine impairs working memory and reduces prefrontal activity associated with inhibition of AMPA receptor GluR2/3 subunit expression12
In vivo and in vitro inflammatory responses to fine particulate matter (PM2.5) from China and California12
Modes of action considerations in threshold expectations for health effects of benzene12
Shp2 regulates PM2.5-induced airway epithelial barrier dysfunction by modulating ERK1/2 signaling pathway12
JUUL e-liquid exposure elicits cytoplasmic Ca2+ responses and leads to cytotoxicity in cultured airway epithelial cells12
Copper exposure disrupts ovarian steroidogenesis in human ovarian granulosa cells via the FSHR/CYP19A1 pathway and alters methylation patterns on the SF-1 gene promoter12
Buccal micronucleus cytome assay: Inter-laboratory scoring exercise and micronucleus and nuclear abnormalities frequencies in different populations from Brazil12
Differences in teratogenicity of some vitamin K antagonist substances used as human therapeutic or rodenticide are due to major differences in their fate after an oral administration12
A suitable silicosis mouse model was constructed by repeated inhalation of silica dust via nose12
Extended regorafenib treatment can be linked with mitochondrial damage leading to cardiotoxicity12
The unreliability of the reliability criteria in the estimation of QSAR for skin sensitivity: A pun or a reliable law?11
Paraquat mediates BV-2 microglia activation by raising intracellular ROS and inhibiting Akt1 phosphorylation11
Optimization of aqueous aerosol extract (AqE) generation from e-cigarettes and tobacco heating products for in vitro cytotoxicity testing11
Downregulation of vdac2 inhibits spermatogenesis via JNK and P53 signalling in mice exposed to cadmium11
The neuroprotective effect of oxytocin on vincristine-induced neurotoxicity in mice11
Energy disorders caused by mitochondrial dysfunction contribute to α-amatoxin-induced liver function damage and liver failure11
Glycochenodeoxycholic acid impairs transcription factor E3 -dependent autophagy-lysosome machinery by disrupting reactive oxygen species homeostasis in L02 cells11
Comparison of the toxic mechanism of T-2 toxin and deoxynivalenol on human chondrocytes by microarray and bioinformatics analysis11
Therapeutic measures for sulfur mustard-induced ocular injury11
Dechlorination and demethylation of ochratoxin A enhance blocking activity of PXR activation, suppress PXR expression and reduce cytotoxicity11
Effect of combustion-derived particles on genotoxicity and telomere length: A study on human cells and exposed populations11
Harmful chemicals of heat not burn product and its induced oxidative stress of macrophages at air-liquid interface: Comparison with ultra-light cigarette11
Perinatal exposure to the thyroperoxidase inhibitors methimazole and amitrole perturbs thyroid hormone system signaling and alters motor activity in rat offspring11
Mechanism of hepatotoxicity of first-line tyrosine kinase inhibitors: Gefitinib and afatinib11
Comparative genotoxic potential of 27 polycyclic aromatic hydrocarbons in three human cell lines11
Dual role of cadmium in rat liver: Inducing liver injury and inhibiting the progression of early liver cancer11
1,2-Dichloroethane induces cerebellum granular cell apoptosis via mitochondrial pathway in vitro and in vivo11
Glucocorticoid-insulin-like growth factor 1 (GC-IGF1) axis programming mediated hepatic lipid-metabolic in offspring caused by prenatal ethanol exposure11
Subchronic exposure to acrylamide caused behaviour disorders and related pathological and molecular changes in rat cerebellum10
Enhanced mitophagy mediated by the YAP/Parkin pathway protects against DOX-induced cardiotoxicity10
An in vitro study on the transport and phase II metabolism of the mycotoxin alternariol in combination with the structurally related gut microbial metabolite urolithin C10
Background contamination of perfluoralkyl substances in a Belgian general population10
NAD+ in sulfur mustard toxicity10
Frailty syndrome, biomarkers and environmental factors – A pilot study10
Impaired activation of Notch-1 signaling hinders repair processes of bronchial epithelial cells exposed to cigarette smoke10
Repression of mercury accumulation and adverse effects of methylmercury exposure is mediated by cystathionine γ-lyase to produce reactive sulfur species in mouse brain10
Sphingosine 1-phosphate receptor-1 specific agonist SEW2871 ameliorates ANIT-induced dysregulation of bile acid homeostasis in mice plasma and liver10
Clinical implications of ontogenetic differences in the coagulotoxic activity of Bothrops jararacussu venoms10
The dual role of immune response in acetaminophen hepatotoxicity: Implication for immune pharmacological targets10
Vitamin D3 protects against nitrogen mustard-induced apoptosis of the bronchial epithelial cells via activating the VDR/Nrf2/Sirt3 pathway10
Exploration study on serum metabolic profiles of Chinese male patients with artificial stone silicosis, silicosis, and coal worker's pneumoconiosis10
Encapsulation of oxime K027 into cucurbit[7]uril: In vivo evaluation of safety, absorption, brain distribution and reactivation effectiveness10
Exposure to traffic-generated air pollution promotes alterations in the integrity of the brain microvasculature and inflammation in female ApoE-/- mice10
CypD deficiency confers neuroprotection against mitochondrial abnormality caused by lead in SH-SY5Y cell10
Trimeresurus albolabris snakebite treatment implications arising from ontogenetic venom comparisons of anticoagulant function, and antivenom efficacy10
In vivo toxicity assessment of four types of graphene quantum dots (GQDs) using mRNA sequencing10
Advances in sulfur mustard-induced DNA adducts: Characterization and detection10
Evaluation of a high-throughput in vitro endothelial cell migration assay for the assessment of nicotine and tobacco delivery products10
Ochratoxin A induces reprogramming of glucose metabolism by switching energy metabolism from oxidative phosphorylation to glycolysis in human gastric epithelium GES-1 cells in vitro10
Differential response of human T-lymphocytes to arsenic and uranium10
Differential coagulotoxicity of metalloprotease isoforms from Bothrops neuwiedi snake venom and consequent variations in antivenom efficacy10
Towards a recommended biomonitoring strategy for assessing the occupational exposure of roofers to PAHs10
Urinary biomonitoring of subjects with different smoking habits. Part II: an untargeted metabolomic approach and the comparison with the targeted measurement of mercapturic acids10
MicroRNA-195-3p promotes hepatic stellate cell activation and liver fibrosis by suppressing PTEN expression10
Chronic cadmium exposure induces epithelial mesenchymal transition in prostate cancer cells through a TGF-β-independent, endoplasmic reticulum stress induced pathway10
Refinement of health-based guidance values for cadmium in the French population based on modelling10
Systematic comparison of the male reproductive tract in fetal and adult Wistar rats exposed to DBP and DINP in utero during the masculinisation programming window10
Glutathione is a potential therapeutic target for acrolein toxicity in the cornea10
LncRNA Meg3-mediated regulation of the Smad pathway in atRA-induced cleft palate10
Meloxicam methyl group determines enzyme specificity for thiazole bioactivation compared to sudoxicam10
Microcystin-LR impairs glucose metabolism in pancreatic β cells in vivo and in vitro10
Alpha-lipoic acid attenuates silica-induced pulmonary fibrosis by improving mitochondrial function via AMPK/PGC1α pathway activation in C57BL/6J mice9
Paternal nicotine exposure promotes hepatic fibrosis in offspring9
Getting stoned: Characterisation of the coagulotoxic and neurotoxic effects of reef stonefish (Synanceia verrucosa) venom9
A lncRNA Gpr137b-ps/miR-200a-3p/CXCL14 axis modulates hepatic stellate cell (HSC) activation9
TP53-induced glycolysis and apoptosis regulator (TIGAR) ameliorates lysosomal damage in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-mediated mouse model of Parkinson’s disease9
Tributyltin and triphenyltin induce 11β-hydroxysteroid dehydrogenase 2 expression and activity through activation of retinoid X receptor α9
Grouping of phthalates for risk characterization of human exposures9
Exploration of zebrafish larvae as an alternative whole-animal model for nephrotoxicity testing9
Possible role of n-hexane as an endocrine disruptor in occupationally exposed women at reproductive age9
A versatile toxicity evaluation of ethyl carbamate (urethane) on zebrafish embryos: Morphological, physiological, histopathological, immunohistochemical, transcriptional and behavioral approaches9
Cigarette Smoke Extract induces H19 in Esophageal Squamous Cell Carcinoma in Smoking Patients: Based on A Chronic Exposed Cell Model9
Are pigs a suitable animal model for in vivo metabolism studies of new psychoactive substances? A comparison study using different in vitro/in vivo tools and U-47700 as model drug9
Interactions of bisphenol diglycidyl ethers with estrogen receptors α: Fluorescence polarization, reporter gene, and molecular modeling investigations9
Effects of Ochratoxin A exposure on DNA damage in porcine granulosa cells in vitro9
Platelets prevent the development of monocrotaline-induced liver injury in mice9
Human phase I in vitro liver metabolism of two bisphenolic diglycidyl ethers BADGE and BFDGE9
Comparison of the toxicity of sulfur mustard and its oxidation products in vitro9
Local renal complement activation mediates immune kidney injury by inducing endothelin-1 signalling and inflammation in trichloroethylene-sensitised mice9
N-acetyl cysteine protects against chlorine-induced tissue damage in an ex vivo model9
Metabolism of glyphosate by the human fecal microbiota9
Effect of PM10 on pulmonary immune response and fetus development9
DNA damage in colon mucosa of Pirc rats, an Apc-driven model of colon tumorigenesis8
Arsenic exposure impairs intestinal stromal cells8
Analysis of serum metabolome of workers occupationally exposed to hexavalent chromium: A preliminary study8
Application of HepG2/C3A liver spheroids as a model system for genotoxicity studies8
A genome-wide screen for differentially methylated long noncoding RNAs identified that lncAC007255.8 is regulated by promoter DNA methylation in Beas-2B cells malignantly transformed by NNK8
Monomethylated arsenic was the Major methylated arsenic in Red blood cells of acute promyelocytic leukemia patients treated with arsenic trioxide8
Sex-specific effects of triphenyltin chloride (TPT) on thyroid disruption and metabolizing enzymes in adult zebrafish (Danio rerio)8
The mouse Anxa6/miR-9-5p/Anxa2 axis modulates TGF-β1-induced mouse hepatic stellate cell (mHSC) activation and CCl4-caused liver fibrosis8
The MIR100HG/miR-29a-3p/Tab1 axis modulates TGF-β1-induced fibrotic changes in type II alveolar epithelial cells BLM-caused lung fibrogenesis in mice8
Derivation of an occupational exposure limit for benzene using epidemiological study quality assessment tools8
Genotoxicity of cationic lipopeptide nanoparticles8
Molecular determinants of binding of non-oxime bispyridinium nerve agent antidote compounds to the adult muscle nAChR8
Mechanistic understanding of dendritic cell activation in skin sensitization: additional evidences to support potency classification8
Transfer of α-synuclein from neurons to oligodendrocytes triggers myelin sheath destruction in methamphetamine administration mice8
Investigation of cardiac glycosides from oleander in a human induced pluripotent stem cells derived cardiomyocyte model8
Bioactivation of trichloroethylene to three regioisomeric glutathione conjugates by liver fractions and recombinant human glutathione transferases: Species differences and implications for human risk 8
3-Monochloropropane-1,2-diol causes spermatogenesis failure in male rats via Sertoli cell dysfunction but not testosterone reduction8
FBXO22, ubiquitination degradation of PHLPP1, ameliorates rotenone induced neurotoxicity by activating AKT pathway8
Suppression of Th2 cytokines as a potential mechanism for reduced antibody response following PFOA exposure in female B6C3F1 mice8
High mobility group box-1 protects against Aflatoxin G1-induced pulmonary epithelial cell damage in the lung inflammatory environment8
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