Toxicology Letters

Article	Citations
The MIR100HG/miR-29a-3p/Tab1 axis modulates TGF-β1-induced fibrotic changes in type II alveolar epithelial cells BLM-caused lung fibrogenesis in mice	61
Toxicokinetic relationship between the adducts in globin and their cleavage products in the urine: Implications for human biomonitoring	48
Non-alcoholic fatty liver disease changes the expression and activity of hepatic drug-metabolizing enzymes and transporters in rats	41
Exosomal miR-196b secreted from bronchial epithelial cells chronically exposed to low-dose PM2.5 promotes invasiveness of adjacent and lung cancer cells	40
An approach to evaluate metabolite-related phototoxicity with combined use of photochemical properties and skin deposition	37
Cognitive changes after methanol exposure: Longitudinal perspective	36
Analysis of the microRNA and mRNA expression profile of ricin toxin-treated RAW264.7 cells reveals that miR-155-3p suppresses cell inflammation by targeting GAB2	33
The mouse Anxa6/miR-9-5p/Anxa2 axis modulates TGF-β1-induced mouse hepatic stellate cell (mHSC) activation and CCl4-caused liver fibrosis	32
P02-46 Cultivation conditions in microfluidic environments: insights from 2D and 3D cell culture models	30
S05-03 The development of a human liver-based In Vitro test battery to detect liver steatotic potential of chemicals from various applicability domains	30
Effects of chlorpyrifos on transient receptor potential channels	30
P07-09 Spatio-temporal multi-omics analysis of lung tissue and matched biofluids identifies circulatory safety biomarkers for monitoring inhaled drug induced lung injury	28
P01-39 Mitochondrial toxicity screening to support the R&D crop protection pipeline	28
P11-01 BPS and BPF by acting as mitochondrial disrupting chemicals cause changes in energy metabolism in human ovarian granulosa cells	27
P02-47 A rat in vitro 3D airway model for translational toxicology	26
P02-26 Optimized iPSC-derived hepatocytes offer a novel liver cell model for in vitro predictive toxicity and drug efficacy studies	24
P09-10 The synthetic cannabinoid ADB-FUBINACA disrupts mitochondrial biogenesis of NG108-15 neuroblastoma cells during neuronal differentiation at human-relevant concentrations	24
P12-13 Role of endoplasmic reticulum stress in sunitinib-induced hepatotoxicity	24
S20-04 Generic pharmacokinetic models for mother-to-offspring transfer of environmental chemicals	24
P08-03 Comprehensive digital documentation and computer-assisted evaluation of the skeleton of Alizarin Red and Alcian Bluestained rat foetuses	23
P17-07 Prenatal exposure to acrylamide and metabolic status at 20 years of age: a prospective biomarker-based cohort study from Denmark	23
P07-05 Miniaturization of haematology sampling in rodents on toxicology studies	22
P21-54 Searching for links in binding patterns among androgen and progesterone receptor ligands	22
The toxicology of inhaled nanomaterials and examples of risk assessment and regulation	21
P14-06 The cytotoxicity of bortezomib in AC16 cardiac cells and possible therapeutic options involving Nrf2	21

P19-50 In-chemico reactivity methods based on molecular initiating event of skin sensitization: refinements and possible application to cosmetic formulations	21
P07-18 Acute phase proteins in Göttingen minipigs: comparison between haptoglobin, Pig-MAPP and CRP in the context of a vaccine study	21
P13-36 In silico analysis of positive and negative effects of isothiocyanates in breast cancer	20
P06-04 Advancing bladder cancer detection: unveiling a novel urinary biomarker panel through metabolomics	20
P08-10 Advancing the use of New Approach Methodologies for assessing teratogenicity using a tiered approach: metabolism consideration to improve the human relevance	20
P02-22 Establishment of a microfluidic neurotoxicity screening model using human iPSCs-differentiated motor neurons within the New Approach Methodologies for chemical safety developed for Precision To	20
P19-03 Integration of transcriptomics data for ED assessments using an Adverse Outcome Pathway Network approach	20
P20-27 Zinc suphide – considerations and challenges for acute inhalation toxicity testing and classification under REACH	20
P08-21 Lack of genotoxicity of Rhamnus Purshiana, Sennae Fructus, and Rhamnus Frangula in a micronucleus assay in vitro (OECD 787)	19
P22-02: The Renal Proximal Tubule TXG-MAPr: Safety Assessment Based On Quantitative Gene Network Analysis	19
LP-17: Evaluation of Genistein as a Mitochondrial Modulator and its Effects on Sperm Motility	18
P14-04 Compartmental toxicokinetic model for urinary excretion of cleavage products resulting from adducts with globin	18
LP-27: Combination of air- and biomonitoring to control cadmium exposure at the workplace	18
P16-01 Silver nanoparticles suppressed retinoic acid-induced neuronal differentiation in SH-SY5Y cells	18
P19-08 New values of occupational exposure limits (OELs) of inhalation anesthetics: enflurane, isoflurane, sevoflurane and desflurane in Poland	18
P16-05 Influence of the new potential antidepressant SMe1EC2M3 treatment on neuronal outgrowth and arborization	18
P03-03 Autopsy findings and toxicological results in Khat-related fatalities in Jazan, Saudi Arabia	17
P25-13: Polo-like kinase 4 (PLK4) Safety Review – distilling the risks with a rapid augmented intelligence approach	17
P23-05: Urinary monohydroxyl-polycyclic aromatic hydrocarbons and metals in firefighters with active participation in controlled structure fires	17
P08-15 Assessing of in vitro genotoxicity testing strategy for T-2 mycotoxin	16
P17-26 Assessment of anabolic steroids impact on 5β-reductase by virtual screening and in vitro approaches	16
S-29-02 Assessing the risk of mitochondrially active compounds in medicines development	16
P08-18 Predicting non-genotoxic carcinogenic potential of agrochemicals: a mechanistic approach	16
P04-19 Selecting drug like structures using in silico tools	16
P08-08 Toxicogenic effects of leaf extracts from an Andean medicinal plant	16
P19-07 Dermal occupational exposure assessment – comparison of selected modeling tools	16
P03-21 Magic mushrooms and psilocybin: pharmacokinetics, pharmacodynamics, and clinical applications	16
P22-31: Training the next-generation toxicologists	15
P22-35: Mapping of DNT NAMs’ signaling pathways in human physiology and disease for regulatory application	15
P22-16: Heated tobacco and e-vapour products induce lower biological activity compared to cigarettes using the ToxProfiler assay	15
P05-06 Protective role of peroxiredoxin V against UVB-induced apoptosis of epidermal keratinocytes	15
P19-05: Comparison of in vitro and in vivo study results for classification of plant protection products	14
P13-07 Addition of physiologically relevant conditions has the potential to effect the toxicology of engineered nanomaterial hazards in an in vitro co-culture of the alveolar region of the lung	14
P17-36: Ti-alloy (TiAl6Nb7) metal powder toxicity in human embryonic kidney (HEK-293T) cell line	14
A pharma stepwise approach to the evaluation of Nitrosamines in drug products: regulatory scenario and the role of in silico approaches	14
Acute phase response and inflammation in mice following exposure to metal oxide nanoparticles	14
P06-22 Reproductive and developmental toxicity testing of a complex UVCB: implications of current dose setting advice under REACH for generating meaningful study outcomes	14
LP-40: Non-clinical Safety profile of a new i.v. Formulation of Rifabutin (BV100) – an Opportunity for new Treatments	14
P21-17 Risk assessment of chemicals in the Dutch red meat production chain	14
HUB Organoids™ improve pre-clinical toxicology, metabolism, and pharmacokinetic studies for drug discovery and development	14
Occupational welding exposure and lung cancer-related epigenetic modifications	14
P21-31 Criteria for selecting physiologically-based kinetic models for use in developing new models for data-poor analogues via a read-across approach	14
P22-17 Acrylamide exposure estimates in the EuroMix biomonitoring study using a probabilistic approach	14
LP-46: Counterfeit drugs awareness among a Mexican sample: An underappreciated health risk	14
Assessment of the toxic effects of 2-dodecanone in the insect model species Drosophila melanogaster	13
P13-07: High-dimensional profiling of immune response to vaccines using bio-stabilized and injectable natural human skin	13
CEC07-03 Towards internal threshold of toxicological concern (iTTC): Implementation of Pharmacokinetics (PK) in the safety assessment	13
S09-03: NAMs in DART testing of pharmaceuticals under ICHS5(R3)	13
PL04-01 Challenges and opportunities for regulatory toxicology under the chemicals strategy for sustainability	13
P10-09: Toxicological aspects of the Horizon EDIAQI project	13

Comparison of genotoxic activity of benzimidazole pesticides	13
Reviewers	13
P09-46: Preliminary results of the second National Human Biomonitoring program in Slovenia: bisphenols, parabens, PFAS, glyphosate and trace elements in children and adolescents	13
S-01-03 Integrating in vitro distribution kinetics analysis in IVIVE-PBK	13
S12A-03: Occupational exposure to copper in dust: Chemical characterization and impact on regulation	13
S-17-02 Prioritization of contaminants for evaluation in food by WHO/FAO expert committees	13
KL02 | EUROTOX Lecture Award	13
S-03-02 Development of T2 MRI biomarker of neurotoxicity as a noninvasive quantitative approach	13
SOC-I-06 Differentially expressed microRNAs in human bronchial epithelial cells after exposure to nanofibrillar, microfibrillar or nanocrystalline cellulose	13
P09-34: Unraveling hormonal dependencies and associated species-specificities of neurodevelopmental key events to improve EDC risk assessment	13
Gentamicin administration leads to synaptic dysfunction in inner hair cells	12
OS03-10: Predictive Modeling of Deltamethrin Exposure in Fetal Brain Tissue: Implications for Human Health Risk Assessment	12
LP-10 Comparative analysis of occupational exposure limits (OELs) for inhibiting RNA therapeutics	12
The harmful acute effects of clomipramine in the rat liver: Impairments in mitochondrial bioenergetics	12
Comparative effects of e-cigarette and conventional cigarette smoke on in vitro bronchial epithelial cell responses	12
Evidence for adduction of biologic amines with reactive metabolite of 8-epidiosbulbin E acetate in vitro and in vivo	12
Exploring potential structure-activity relationships of graphene-based materials.	12
S23-02 Assessment and modelling of metabolites: the conazole case study	12
Lysosomal membrane permeabilization mediated apoptosis involve in perphenazine-induced hepatotoxicity in vitro and in vivo	12
Cigarette smoke extract mediates cell premature senescence in chronic obstructive pulmonary disease patients by up-regulating USP7 to activate p300-p53/p21 pathway	12
A suitable silicosis mouse model was constructed by repeated inhalation of silica dust via nose	12
S11-01: A regulatory perspective: hazard identification and potency classification	12
Batch-to-batch variation of Ames test results for S. typhimurium TA 98 and TA 100 correlates with growth kinetics	12
Evaluating applicability domain of acute toxicity QSAR models for military and industrial chemical risk assessment	12
A battery of assays for chasing ricin and its activity	12
P17-27: Role of oxidative stress in microplastic polymethyl methacrylate (PMMA)-induced hepatotoxicity with HepG2/THP-1 co-culture model	11
P03-22: Sensitivity of primary human hepatocytes and HepG2 cells for genotoxicity testing of N-nitrosamines in the in vitro alkaline comet assay	11
LP-20 Halogen-free flame retardant is friendlier to the aquatic environment than PBDEs	11
Toxicity prediction using target, interactome, and pathway profiles as descriptors	11
P17-03 Toxic and essential metals in breast milk: Preliminary results from Bosnia and Herzegovina	11
S23-01 The ASPIS-initiated Safety Profiling Algorithm (ASPA): setting the stage for Next-Generation Risk Assessment	11
A critical review of microplastics toxicity and potential adverse outcome pathway in human gastrointestinal tract following oral exposure	11
Do urinary metabolites reflect occupational exposure to organophosphate flame retardants? A case study in electronic waste recycling workers.	11
The suitability of a polydimethylsiloxane-based (PDMS) microfluidic two compartment system for the toxicokinetic analysis of organophosphorus compounds	11
P01-62 Development of an in vitro model of dry nose	11
P02-18 Using individual-centric model to detect immune-mediated idiosyncratic drug-induced liver injury at preclinical stage	11
Toxicokinetic analysis of the highly toxic nerve agent VX in commercially available multi-organ-chips – Ways to overcome compound absorption	11
BDE-47 induces metabolic dysfunction-associated steatotic liver disease (MASLD) through CD36-mediated increased fatty acid uptake and PPARα-induced abnormal fatty acid oxidation in BALB/c mice	11
P17-09: Polystyrene microplastics of varying sizes and shapes induce distinct redox and mitochondrial stress responses in a Caco-2 monolayer	11
The relative efficacy of chemically diverse small-molecule enzyme-inhibitors against anticoagulant activities of Black Snake (Pseudechis spp.) venoms	11
S24-02 Biomarkers of neurodevelopmental effect can reduce uncertainty when assessing the risks of thyroid disrupting chemicals	11
P25-07 Do co-formulants influence PPP genotoxicity? – a case study	11
CEC04-02 Comparison of outdoor and indoor air pollution on cardio-pulmonary health	11
P21-56 Shedding light on the epidermal alterations induced by blue light and heated tobacco products co-exposure: an in vitro study	10
P19-32 Advancing the application of New Approach Methodologies (NAMs) in systemic toxicity assessment of cosmetic ingredients: insights from cosmetics Europe long range science strategy (2016–2022) ca	10
CEC01-01 Introduction into the AOP framework: Integrating Theory and Practice in AOP Development	10
Endocrine disruptors and microplastics: facing complexity with connection	10
P01-63 The secretion of interleukin 18 by reconstructed human epidermis is a biomarker for in vitro prediction of skin photosensitization	10
P02-30 Generation and evaluation of a historical control database for the creation of assay acceptance criteria for a comparative in vitro hepatic enzyme assay	10
P23-11 Assessment of PAH exposure in trainee firefighters using a PAH CALUX bioassay	10
OS02-03 Using a systems biology approach to construct adverse outcome pathway networks aligned with the FAIR principles	10
Adefovir accumulation in the renal interstitium triggers mast cell degranulation and promotes renal interstitial fibrosis	10
P26-02 Ensuring pharmaceutical packaging safety: an integrated approach for assessing extractable profiles and toxicological risk	10
P03-03 Quantitative in vitro to in vivo extrapolation (QIVIVE) for liver-induced thyroid toxicity risk assessment	10
Binding of ligands to the aryl hydrocarbon receptor: An overview of methods	10
S12-06 Finding European research funding and writing a competitive research proposal	10
P18-15 Determination of tramadol and its metabolite O-desmethyltramadol in blood and vitreous humor samples	10
Title Page	10
P19-26 Moving towards a framework for in vitro risk assessment and determination of human relevance of rodent liver-mediated thyroid toxicity	10
S23-04 RapidTox: decision-based workflow environment to advance human health assessment	10
S02-04 Computational Toxicology in Drug Safety	10
P13-03 Comparative study of mutagenic/antimutagenic and genotoxic/antigenotoxic activities of ethanolic and aqueous extracts prepared from Arbutus unedo fruits	10
Corrigendum to “Furocoumarins affect hepatic cytochrome P450 and renal organic ion transporters in mice” [Toxicol. Lett. 209 (2012) 67–77]	10
P09-18 Comprehensive search for genes that vary across three developmental neurotoxicants	10
Low-cost toxicogenomic profiling of Human iPSC derived minibrain reveals key adverse outcome pathways	9
P11-26 Exosomes derived from primed mesenchymal stem cells improve cell viability on an APAP-induced hepatic injury in vitro model	9
Uptake, fate, and gut toxicity of perfluorooctanoic acid (PFOA) in vitro	9
miR-520f-3p blocks MNNG-induced gastric precancerous lesions via the KLF7/NFκB pathway	9
The influence of the anticancer drugs doxorubicin and mitoxantrone on cardiac metabolism and autophagy	9
P12-08 Biological evaluation of pharmaceuticals inhibiting 11β-hydroxylase identified by virtual screening	9
In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay	9
Editorial Board	9
P23-03: Applying the Multiple Path Particle Dosimetry model for assessing Occupational Exposure to Active Pharmaceutical Ingredients	9
S-31-01 Setting the scene: human health impacts of micro- and nanoplastics (MNPs)	9
Editorial Board	9
Transcriptomic and morphological study of the influence of all-trans retinoic acid’s duration exposure on the zebrafish developmental mechanisms	9
P12-32 An all-human cell based tri-culture system distinguished through morphology, longevity, and functionality	9
PPARγ activation inhibits endocytosis of claudin-4 and protects against deoxynivalenol-induced intestinal barrier dysfunction in IPEC-J2 cells and weaned piglets	9
S-26-01 Methylmercury-induced modification of selenocysteine in selenoprotein P – Implication to its physiological function	9
Toxicology brought to justice: Risk assessments and liability assessments related to high levels of PFAS	9

P16-21: Applications of an isogenic human iPSC-derived blood-brain barrier (BBB) model	9
Rodent thyroid toxicity and potential child neurodevelopmental impairment	9
Effects of chrysene and benzo-a-pyrene on placental estrogen receptors	9
An in vitro lung-on-chip model of Streptococcus pneumoniae infection as a preclinical efficacy tool	9
Think beyond cytotoxicity: Does toxic-induced immunogenic cell death (ICD) contribute to lung inflammation and serve as predictive biomarker?	8
Editorial Board	8
P12-59 Assessing the placental transfer of dexamethasone via ex vivo human placenta perfusions: a step-up towards model informeddrug dosing in pregnancy	8
Gut microbiota and human health through lifespan	8
P01-04: Development of an Adverse Outcome Pathway (AOP) to assess the neurotoxicity of the exposure to benzo(a)pyrene	8
S-05-02 How can grouping and read-across support safe(r)-by-design of nanomaterials and advanced materials? GRACIOUS	8
CEC01-01: A hands-on introduction to applied artificial intelligence in toxicology	8
P04-06: Toxicity of particulate matter from experimental burning of domestic waste	8
S13-01: How far are we with the implementation of NGRA for cosmetics?	8
How can systematic review methods help now and also prepare for future decision making on mechanistic data?	8
P17-30: Amorphous silica nanomaterials effects on human dendritic cells promote the T-cell response to the pneumallergen Bet v 1a	8
P03-04 Validation of an analytical method to identify and quantify selected amphetamine-related drugs (ARDs) in whole blood (WB) using UPLC-qTOF-MS after extraction by MMSPE	8
P25-05: Media representation of Glyphosate in Slovenian Printed Media over 10 year period	8
P22-11: Case study of resveratrol as a cosmetic ingredient for systemic toxicity using the new approachmethodologies of next generation risk assessment	8
CEC06-03: Documenting pesticide exposures from field studies: what is known and why we should know more	8
P10-03: Cadmium levels are related to clonal hematopoiesis and mortality	8
P01-02: An updated adverse outcome pathway network on chemical-induced liver steatosis	8
P08-12 The surfactant co-formulant POEA in the glyphosate-based herbicide RangerPro but not glyphosate alone causes necrosis and ER stress in mammalian cell lines	8
Toxicity of nanomaterials in the user phase	8
P22-08: New strategies for the safety assessment of proteins in food/feed derived from biotechnology – the way forward	8
P04-16 In silico applications for the prediction and hazard assessment of transformation products originated from water disinfection treatment processes	8
P11-05 Toxic microelements levels in the blood clot of wild boar (Sus scrofa) for monitoring the contamination and biomarkers changes	8
P22-03: Read-Across case study – from hypothesis to regulatory acceptance	8
KL06 | Keynote Lecture	8
P06-40: Integrating physiologically-based pharmacokinetic modelling and 'omics data to derive a health-based guidance value for perfluorooctanoic acid	8
P10-12 Investigation of the effects of endocrine disruptors on T cells differentiation	8
LncRNA PCA3 promotes antimony-induced lipid metabolic disorder in prostate cancer by targeting MIR-132-3 P/SREBP1 signaling	7
P22-05 Identification and hazard assessment of oligoesters, nonintentionally added substances present in food contact coating extracts	7
Machine learning in silico models in chemical hazard identification	7
P22-27 Exposure assessment of total DON in urine of Portuguese adult population under the HBM4EU aligned studies	7
An in vitro harmonized strategy to assess the toxicity of chemicals using multiple human induced pluripotent stem cell (hiPSC)-derived models	7
P26-11: Acute and subacute toxicity profiles in Sprague-Dawley (SD) rats treated with Piperis Longi Fructus (PLF) Powder	7
WGCNA in vivo rat liver co-expressed modules to derive human in vitro reporters associated with pathology	7
S-20-03 Towards an ADME-competent human 4-organ chip for risk assessment	7
Suppression of Th2 cytokines as a potential mechanism for reduced antibody response following PFOA exposure in female B6C3F1 mice	7
Triphenyltin (TPT) exposure causes SD rat liver injury via lipid metabolism disorder and ER stress revealed by transcriptome analysis	7
Nephrotoxic liability assessment using hiPSC-derived renal glomerular and proximal tubular epithelial cells	7
Corrigendum to “Quantitative skin exposure assessment of metals: A case study” [Toxicol. Lett. 351 (2021) 135–144]	7
Cytotoxic effects of bisphenol A alternatives in TM3 mice Leydig cells in vitro	7
Exogenous activation of toll-like receptor 5 signaling mitigates acetaminophen-induced hepatotoxicity in mice	7
Hypercholesterolemia reduces the expression and function of hepatic drug metabolizing enzymes and transporters in rats	7
P16-17 The senescence-associated secretory phenotype (SASP) from colorectal cancer cells induce neurotoxicity: novel mechanism involvement of CD38-NAD+ pathways	7
LP-37 Biokinetics of fluorophore-conjugated microplastics in marine mussels	7
The exposome: drugs, toxicants, and metabolites	7
P11-02: Online methods and tools for assessing chemical exposure in humans: a systematic scoping review for the ONTOX project	7
Molecular mechanisms of hepatotoxic cholestasis by clavulanic acid in human hepatocytes	7
Editorial Board	7
SOC-III-09 Comparison of key players involved in endocrine-related effects across different vertebrate species	7
Aristolochic acid I promotes renal tubulointerstitial fibrosis by up-regulating expression of indoleamine 2,3-dioxygenase-1 (IDO1)	7
Analysis of structure phototoxicity relationship towards the de-risking of phototoxic liabilities in early drug discovery	7
P17-12 Molecular network pathway analysis of arsenic and cisplatin in cancer	7
Expression of Concern: “α-Zearalanol attenuates oxLDL-induced ET-1 gene expression, ET-1 secretion and redox-sensitive intracellular signaling activation in human umbilical vein endothelial cells” [To	7
P22-11 Current challenges in water quality require advanced risk assessment	7
Nicotine facilitates pancreatic fibrosis by promoting activation of pancreatic stellate cells via α7nAChR-mediated JAK2/STAT3 signaling pathway in rats	7
P21-16 Cytotoxicity: regulatory definitions versus scientific knowledge	7
LP-04: Adverse Outcome Pathways of Toxicity-Induced Dry Eye: implication of ferroptosis and pyroptosis in corneal neuroepithelial entity	7
LP-23 Molecular glue degrader reproductive toxicity: what did we learn?	7
P10-25: Cytotoxic and genotoxic effects of particulate matter emitted in beauty salons	7
Screening for new ligands of the MB327-PAM-1 binding site of the nicotinic acetylcholine receptor	7
P15-02: Exploring the impact of citrinin mycotoxin on SH-SY5Y cells: Apoptosis, cell cycle, oxidative stress, and mitochondrial function	7
20-Hydroxytetraenoic acid induces hepatic fibrosis via the TGF-β1/Smad3 signaling pathway	7
Heme induces inflammatory injury by directly binding to the complex of myeloid differentiation protein 2 and toll-like receptor 4	7
Borderline ranges for in chemico and in vitro skin sensitization methods determined from ring trial data - acknowledging experimental uncertainty in defined approaches	7
Introducing the OECD guidance document on occupational biomonitoring: A harmonized methodology for deriving occupational biomonitoring levels (OBL)	7
Medaka eggs tests, a screening tool to evaluate the Endocrine Disruption* potential of new ingredients?	7
Inhibition of NLRP3 inflammasome by glibenclamide attenuated dopaminergic neurodegeneration and motor deficits in paraquat and maneb-induced mouse Parkinson’s disease model	7
Editorial Board	6
Human kidney organoids model of Esculentoside A nephrotoxicity to investigate the role of epithelial-mesenchymal transition via STING signaling	6
LP-25: The curious case of Adverse Outcome Pathways: the stressor agnostic approach bridging disciplines by embracing evidence from diverse initiating factors	6
P11-19 Chaperone-mediated autophagy regulates the degradation of sortilin in the liver	6
P24-06: Applicability of the DPRA on mixture testing: Challenges and opportunities	6
P13-03 Propylene glycol monobuthyl ether (PGBE) exerts higher toxicity than propylene glycol monomethyl ether (PGME) in human lung cells	6
P14-09 Oxidative bioactivation of the sodium-glucose cotransporter 2 inhibitor Dapagliflozin: identification of potential biomarkers	6
P24-31: The Human Health dataset of the approved biocidal active substances	6
Use of in vitro metabolomics in NRK cells to help predicting nephrotoxicity and differentiating the MoA of nephrotoxicants	6
Developing a quick, affordable and effective screening multi-method for most commonly used veterinary antibiotics in livestock products	6
Cisterna Magna Administration: A Robust Alternative Non-Systemic Route of Delivery for New Drug Entities in Non-Human Primates	6
Ecotoxicological influence of single-walled carbon nanotubes, graphene nanoribbons, and graphene quantum dots on marine microalgae	6
The Minipig – A Rising Star for Nonclinical Safety Testing in Support of Development of Paediatric Medicines?	6
P24-25: Comparative Pharmacokinetics and Safety Assessment of Nanocrystal Formulated Zileuton at the Gastrointestinal Tract Reveals Sex-Dependent Mucosal Immune Response, Epithelial Permeability and D	6
P23-09: Filling in safety data sheets for data-poor substances relevant to drug development	6
P25-02: Derivation of a target value of acrylic acid in drinking water	6
SOC-VI-02 Establishment and validation of co-culture system of human colon organoids and THP-1 derived macrophages	6
Applying the adverse outcome pathways network for understanding and predicting neurotoxicity	6
Reevaluation of Concentration addition: ligands with different maximal effects cause curvature of isoboles	6
Development of multiparametric kinetic measurements and analytics workflows for the generation of an IPSC derived cardiomyocyte based cardiovascular model	6
LP-32: Chronic exposure to graphene oxide can modify the digestive enzymes activity of Acheta domesticus	6
P18-02 The validation study of spectro-DPRA, which is improved in chemico alternative assay for skin sensitization test	6
P24-10: Lessons learned in method's validation	6
P16-16 Mitochondrial respiratory chain inhibitor pesticides alter expression of dopa decarboxylase and growth differentiation factor 15 in SH-SY5Y neurons	6
P10-04 Development of alternative test method for immunotoxicity prediction on chemical substances through profiling of cytokines production from THP-1 cell line	6