OOIR: Observatory of International Research

Papers

(The TQCC of Drug Development and Industrial Pharmacy is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Macrophage targeting with the novel carbopol-based miltefosine-loaded transfersomal gel for the treatment of cutaneous leishmaniasis: in vitro and in vivo analyses	50
Emulgel: an effective drug delivery system	41
Medical application of biomimetic 4D printing	40
Synthesis of PEG-4000-co-poly (AMPS) nanogels by cross-linking polymerization as highly responsive networks for enhancement in meloxicam solubility	38
Stereolithography 3D printing technology in pharmaceuticals: a review	32
Glycyrrhizic acid-based self-assembled micelles for improving oral bioavailability of paeoniflorin	31
PEGylated drug delivery systems in the pharmaceutical field: past, present and future perspective	29
3D printing of immediate-release tablets containing olanzapine by filaments extrusion	26
Development and machine-learning optimization of mucoadhesive nanostructured lipid carriers loaded with fluconazole for treatment of oral candidiasis	26
Docetaxel/dimethyl-β-cyclodextrin inclusion complexes: preparation, in vitro evaluation and physicochemical characterization	25
A mechanistic review on the dissolution phase behavior and supersaturation stabilization of amorphous solid dispersions	20
Potential alternatives to current cholinesterase inhibitors: anin silicodrug repurposing approach	20
Development, validation and application of physiologically based biopharmaceutics model to justify the change in dissolution specifications for DRL ABC extended release tablets	19
Extemporaneous printing of diclofenac orodispersible films for pediatrics	19
Ternary solid dispersions: classification and formulation considerations	19
Preparation, characterization, and in vivo evaluation of perphenazine-loaded nanostructured lipid carriers for oral bioavailability improvement	18
Surfactant-free amorphous solid dispersion with high dissolution for bioavailability enhancement of hydrophobic drugs: a case of quercetin	18
A key role by polymers in microneedle technology: a new era	17
Dual loading of Nigella sativa oil-atorvastatin in chitosan–carboxymethyl cellulose nanogel as a transdermal delivery system	17
Development and evaluation of puerarin-loaded controlled release nanostructured lipid carries by central composite design	17
A review of stimuli-responsive polymeric micelles for tumor-targeted delivery of curcumin	16
Colon-specific tablets containing 5-fluorouracil microsponges for colon cancer targeting	16
Colon targeted dosage form of Capecitabine using folic acid anchored modified carbon nanotube: in vitro cytotoxicity, apoptosis and in vivo roentgenographic study	16
Formulation of chitosan coated nanoliposomes for the oral delivery of colistin sulfate: in vitro characterization, ^99mTc-radiolabeling and in vivo biodistribution studies	15
Mixed micelles for enhanced oral bioavailability and hypolipidemic effect of liquiritin: preparation, in vitro and in vivo evaluation	15

Development and characterization of orodispersible film containing cefixime trihydrate	15
Fabrication and optimization of amoxicillin-loaded niosomes: an appropriate strategy to increase antimicrobial and anti-biofilm effects against multidrug-resistant Staphylococcus aureus strains	15
Intranasal drug delivery of sumatriptan succinate-loaded polymeric solid lipid nanoparticles for brain targeting	15
Impact of bile salts and a medium chain fatty acid on the physical properties of self-emulsifying drug delivery systems	14
Improving gallic acid and quercetin bioavailability by polymeric nanoparticle formulation	13
Development of novel biopolymer-based nanoparticles loaded cream for potential treatment of topical fungal infections	13
Microneedle system: a modulated approach for penetration enhancement	13
Development and evaluation of tofacitinib transdermal system for the treatment of rheumatoid arthritis in rats	13
A rutin nanocrystal gel as an effective dermal delivery system for enhanced anti-photoaging application	12
Emerging theranostics to combat cancer: a perspective on metal-based nanomaterials	12
In-use stability studies: guidelines and challenges	12
Carbopol-olive oil-based bigel drug delivery system of doxycycline hyclate for the treatment of acne	12
Development and optimization of drug-loaded nanoemulsion system by phase inversion temperature (PIT) method using Box–Behnken design	12
An updated review of mesoporous carbon as a novel drug delivery system	12
Formulation design and optimization of cationic-charged liposomes of brimonidine tartrate for effective ocular drug delivery by design of experiment (DoE) approach	11
Electrostatic deposition assisted preparation, characterization and evaluation of chrysin liposomes for breast cancer treatment	11
Formulation and performance evaluation of polymeric mixed micelles encapsulated with baicalein for breast cancer treatment	11
Microneedle-assisted transdermal delivery of amlodipine besylate loaded nanoparticles	11
Development and evaluation of proniosomes to enhance the transdermal delivery of cilostazole and to ensure the safety of its application	11
Borneol-modified tanshinone IIA liposome improves cerebral ischemia reperfusion injury by suppressing NF-κB and ICAM-1 expression	11
Intranasal galantamine/chitosan complex nanoparticles elicit neuroprotection potentials in rat brains via antioxidant effect	11
Calcium alginate nanoparticle crosslinked phosphorylated polyallylamine to the controlled release of clindamycin for osteomyelitis treatment	11
Preparation, characterization, and pharmacodynamic study on deep second degree burns of total flavonoids composite phospholipids liposome gel of Oxytropis falcata Bunge	11
Enhancement of oral bioavailability of drugs using lipid-based carriers: a meta-analysis study	11
PEGylated solid lipid nanoparticles functionalized by aptamer for targeted delivery of docetaxel in mice bearing C26 tumor	10
Development and optimization of tibezonium iodide and lignocaine hydrochloride containing novel mucoadhesive buccal tablets: a pharmacokinetic investigation among healthy humans	10
Analytical method development, validation and forced degradation studies for rutin, quercetin, curcumin, and piperine by RP-UFLC method	10
Residence time and mixing capacity of a rotary tablet press feed frame	10
Nanostructured lipid carrier-mediated lung targeted drug delivery system to enhance the safety and bioavailability of clofazimine	10
Empagliflozin containing chitosan-alginate nanoparticles in orodispersible film: preparation, characterization, pharmacokinetic evaluation and itsin-vitroanticancer activity	10
Improved pharmaceutical properties of ritonavir through co-crystallization approach with liquid-assisted grinding method	9
Functional vinorelbine plus schisandrin B liposomes destroying tumor metastasis in treatment of gastric cancer	9
Pharmacokinetics and brain distribution studies of perphenazine-loaded solid lipid nanoparticles	9
Formulation and evaluation of interpenetrating polymeric network for controlled drug delivery	9
Raloxifene HCl – quercetin co-amorphous system: preparation, characterization, and investigation of its behavior in phosphate buffer	9
Nisin and nisin-loaded nanoparticles: a cytotoxicity investigation	9
In vitro and in vivo evaluation of taste-masked orodispersible tablets of fluoxetine hydrochloride for the treatment of depression	9
Amelioration of physicochemical, pharmaceutical, and pharmacokinetic properties of lornoxicam by cocrystallization with a novel coformer	9
Monoolein-based nanoparticles containing indinavir: a taste-masked drug delivery system	9
Engineered PLGA microspheres for extended release of brexpiprazole: in vitro and in vivo studies	8
Preparation and characterization of hydroxyapatite nanoparticles doped with nickel, tin, and molybdate ions for their antimicrobial effects	8
Comparative study of novel green UV-spectrophotometric platforms for simultaneous rapid analysis of flumethasone pivalate and clioquinol in their combined formulation	8
Development of UV–visible spectrophotometric methods for the quantitative andin silicostudies for cilazapril optimized by response surface methodology	8
Fabrication and characterization of dissolving microneedles for transdermal drug delivery of allopurinol	8
Design and optimization of a probiotic tablet for gastrointestinal tolerance by a simplex-centroid mixture	8
Application of HPMC HME polymer as hot melt extrusion carrier in carbamazepine solid dispersion	8
Sirolimus-exuding core-shell nanofibers as an implantable carrier for breast cancer therapy: preparation, characterization, in vitro cell studies, and in vivo anti-tumor activity	8
Biosynthesis of silver nanoparticles using Citrus hystrix leaf extract and evaluation of its anticancer efficacy against HeLa cell line	8
Topical delivery of pluronic F127/TPGS mixed micelles-based hydrogel loaded with glycyrrhizic acid for atopic dermatitis treatment	7
The potential of intranasal delivery of nanocrystals in powder form on the improvement of zaleplon performance: in-vitro, in-vivo assessment	7

One-pot synthesis of Eu-MOFs for bioimaging and drug delivery	7
Study on the mechanism of treating COVID-19 with Shenqi Wan based on network pharmacology	7
Reckoning γ-Glutamyl-S-allylcysteine as a potential main protease (m^pro) inhibitor of novel SARS-CoV-2 virus identified using docking and molecular dynamics simulation	7
Development and characterization of ibuprofen co-crystals granules prepared via fluidized bed granulation in a one-step process – a design of experiment approach	7
Toward simplified oral lipid-based drug delivery using mono-/di-glycerides as single component excipients	7
Matrix metalloproteinase enzyme responsive delivery of 5-Fluorouracil using Collagen-I peptide functionalized Dendrimer-Gold nanocarrier	7
In vitroandin vivoactivity of thermosensitive liposomes loaded with doxorubicin and cisplatin	7
In-vitro and in-vivo evaluation of taste-masked ibuprofen formulated in oral dry emulsions	7
Development of piperine nanoemulsions: an alternative topical application for hypopigmentation	7
Preparation, characterization and in-Vitro/in-Vivo evaluation of meloxicam extruded pellets with enhanced bioavailability and stability	7
In vitro characterization of tofacitinib loaded novel nanoemulgel for topical delivery for the management of rheumatic arthritis	7
Smart UV-spectrophotometric platforms for rapid green analysis of miconazole nitrate and nystatin in their combined suppositories and in vitro dissolution testing	7
Crystal engineering of valproic acid and carbamazepine to improve hygroscopicity and dissolution profile	7
Preparation and in vitro/in vivo evaluation of a clonidine hydrochloride drug–resin suspension as a sustained-release formulation	6
Solubility determination and solution thermodynamics of olmesartan medoxomil in (PEG-400 + water) cosolvent mixtures	6
New stability chiral RP-HPLC method for degradation products determination in midodrine hydrochloride	6
Nanosuspension coated multiparticulates for controlled delivery of albendazole	6
Intra-articular formulation of colchicine loaded nanoemulsion systems for enhanced locoregional drug delivery: in vitro characterization, ^99mTc coupling and in vivo biodistrib	6
Physicochemical characterization of dapagliflozin and its solid-state behavior in stress stability test	6
Fabrication of a dual stimuli-responsive magnetic nanohydrogel for delivery of anticancer drugs	6
Preparation and evaluation of liposome with ropivacaine ion-pairing in local pain management	6
Preformulation studies of thymopentin: analytical method development, physicochemical properties, kinetic degradation investigations and formulation perspective	6
Development and characterization of pluronic lecithin organogel containing fluocinolone acetonide	6
Fabrication and analysis of chitosan oligosaccharide based mucoadhesive patch for oromucosal drug delivery	6
Development of self-microemulsifying lipid-based formulations of trans-resveratrol by systematically constructing lipid-surfactant-water phase diagrams using long-chain lipids	6
Applicability of Raman and near-infrared spectroscopy in the monitoring of freeze-drying injectable ibuprofen	6
Enhanced full-thickness wound healing viaSophora gibbosaextract delivery based on a chitosan/gelatin dressing incorporating microemulsion	6
Are European marketed acyclovir 5% cream products similar? Comparison with EU and US reference product	6
Novel risperidone orally disintegrating minitablets for pediatric use: patient acceptance and dose adjustment	6
Glibenclamide–malonic acid cocrystal with an enhanced solubility and bioavailability	6
Optimized preparation of eugenol microcapsules and its effect on hepatic steatosis in HepG₂ cells	6
Development and evaluation of a novel methotrexate-loaded electrospun patch to alleviate psoriasis plaques	6
Modulation of gene expression by thymoquinone conjugated zinc oxide nanoparticles arrested cell cycle, DNA damage and increased apoptosis in triple negative breast cancer cell line MDA-MB-231	6
Fabrication of gelatin/silk fibroin/phage nanofiber scaffold effective against multidrug resistantPseudomonas aeruginosa	6
Nanostructured lipid carriers for enhanced in vitro and in vivo schistosomicidal activity of praziquantel: effect of charge	6