Drug Development and Industrial Pharmacy

Article	Citations
Macrophage targeting with the novel carbopol-based miltefosine-loaded transfersomal gel for the treatment of cutaneous leishmaniasis: in vitro and in vivo analyses	50
Emulgel: an effective drug delivery system	41
Medical application of biomimetic 4D printing	40
Synthesis of PEG-4000-co-poly (AMPS) nanogels by cross-linking polymerization as highly responsive networks for enhancement in meloxicam solubility	38
Stereolithography 3D printing technology in pharmaceuticals: a review	32
Glycyrrhizic acid-based self-assembled micelles for improving oral bioavailability of paeoniflorin	31
PEGylated drug delivery systems in the pharmaceutical field: past, present and future perspective	29
3D printing of immediate-release tablets containing olanzapine by filaments extrusion	26
Development and machine-learning optimization of mucoadhesive nanostructured lipid carriers loaded with fluconazole for treatment of oral candidiasis	26
Docetaxel/dimethyl-β-cyclodextrin inclusion complexes: preparation, in vitro evaluation and physicochemical characterization	25
A mechanistic review on the dissolution phase behavior and supersaturation stabilization of amorphous solid dispersions	20
Potential alternatives to current cholinesterase inhibitors: anin silicodrug repurposing approach	20
Development, validation and application of physiologically based biopharmaceutics model to justify the change in dissolution specifications for DRL ABC extended release tablets	19
Extemporaneous printing of diclofenac orodispersible films for pediatrics	19
Ternary solid dispersions: classification and formulation considerations	19
Preparation, characterization, and in vivo evaluation of perphenazine-loaded nanostructured lipid carriers for oral bioavailability improvement	18
Surfactant-free amorphous solid dispersion with high dissolution for bioavailability enhancement of hydrophobic drugs: a case of quercetin	18
A key role by polymers in microneedle technology: a new era	17
Dual loading of Nigella sativa oil-atorvastatin in chitosan–carboxymethyl cellulose nanogel as a transdermal delivery system	17
Development and evaluation of puerarin-loaded controlled release nanostructured lipid carries by central composite design	17
A review of stimuli-responsive polymeric micelles for tumor-targeted delivery of curcumin	16
Colon-specific tablets containing 5-fluorouracil microsponges for colon cancer targeting	16
Colon targeted dosage form of Capecitabine using folic acid anchored modified carbon nanotube: in vitro cytotoxicity, apoptosis and in vivo roentgenographic study	16
Formulation of chitosan coated nanoliposomes for the oral delivery of colistin sulfate: in vitro characterization, 99mTc-radiolabeling and in vivo biodistribution studies	15
Mixed micelles for enhanced oral bioavailability and hypolipidemic effect of liquiritin: preparation, in vitro and in vivo evaluation	15

Development and characterization of orodispersible film containing cefixime trihydrate	15
Fabrication and optimization of amoxicillin-loaded niosomes: an appropriate strategy to increase antimicrobial and anti-biofilm effects against multidrug-resistant Staphylococcus aureus strains	15
Intranasal drug delivery of sumatriptan succinate-loaded polymeric solid lipid nanoparticles for brain targeting	15
Impact of bile salts and a medium chain fatty acid on the physical properties of self-emulsifying drug delivery systems	14
Improving gallic acid and quercetin bioavailability by polymeric nanoparticle formulation	13
Development of novel biopolymer-based nanoparticles loaded cream for potential treatment of topical fungal infections	13
Microneedle system: a modulated approach for penetration enhancement	13
Development and evaluation of tofacitinib transdermal system for the treatment of rheumatoid arthritis in rats	13
A rutin nanocrystal gel as an effective dermal delivery system for enhanced anti-photoaging application	12
Emerging theranostics to combat cancer: a perspective on metal-based nanomaterials	12
In-use stability studies: guidelines and challenges	12
Carbopol-olive oil-based bigel drug delivery system of doxycycline hyclate for the treatment of acne	12
Development and optimization of drug-loaded nanoemulsion system by phase inversion temperature (PIT) method using Box–Behnken design	12
An updated review of mesoporous carbon as a novel drug delivery system	12
Formulation design and optimization of cationic-charged liposomes of brimonidine tartrate for effective ocular drug delivery by design of experiment (DoE) approach	11
Electrostatic deposition assisted preparation, characterization and evaluation of chrysin liposomes for breast cancer treatment	11
Formulation and performance evaluation of polymeric mixed micelles encapsulated with baicalein for breast cancer treatment	11
Microneedle-assisted transdermal delivery of amlodipine besylate loaded nanoparticles	11
Development and evaluation of proniosomes to enhance the transdermal delivery of cilostazole and to ensure the safety of its application	11
Borneol-modified tanshinone IIA liposome improves cerebral ischemia reperfusion injury by suppressing NF-κB and ICAM-1 expression	11
Intranasal galantamine/chitosan complex nanoparticles elicit neuroprotection potentials in rat brains via antioxidant effect	11
Calcium alginate nanoparticle crosslinked phosphorylated polyallylamine to the controlled release of clindamycin for osteomyelitis treatment	11
Preparation, characterization, and pharmacodynamic study on deep second degree burns of total flavonoids composite phospholipids liposome gel of Oxytropis falcata Bunge	11
Enhancement of oral bioavailability of drugs using lipid-based carriers: a meta-analysis study	11
PEGylated solid lipid nanoparticles functionalized by aptamer for targeted delivery of docetaxel in mice bearing C26 tumor	10
Development and optimization of tibezonium iodide and lignocaine hydrochloride containing novel mucoadhesive buccal tablets: a pharmacokinetic investigation among healthy humans	10
Analytical method development, validation and forced degradation studies for rutin, quercetin, curcumin, and piperine by RP-UFLC method	10
Residence time and mixing capacity of a rotary tablet press feed frame	10
Nanostructured lipid carrier-mediated lung targeted drug delivery system to enhance the safety and bioavailability of clofazimine	10
Empagliflozin containing chitosan-alginate nanoparticles in orodispersible film: preparation, characterization, pharmacokinetic evaluation and itsin-vitroanticancer activity	10
Improved pharmaceutical properties of ritonavir through co-crystallization approach with liquid-assisted grinding method	9
Functional vinorelbine plus schisandrin B liposomes destroying tumor metastasis in treatment of gastric cancer	9
Pharmacokinetics and brain distribution studies of perphenazine-loaded solid lipid nanoparticles	9
Formulation and evaluation of interpenetrating polymeric network for controlled drug delivery	9
Raloxifene HCl – quercetin co-amorphous system: preparation, characterization, and investigation of its behavior in phosphate buffer	9
Nisin and nisin-loaded nanoparticles: a cytotoxicity investigation	9
In vitro and in vivo evaluation of taste-masked orodispersible tablets of fluoxetine hydrochloride for the treatment of depression	9
Amelioration of physicochemical, pharmaceutical, and pharmacokinetic properties of lornoxicam by cocrystallization with a novel coformer	9
Monoolein-based nanoparticles containing indinavir: a taste-masked drug delivery system	9
Engineered PLGA microspheres for extended release of brexpiprazole: in vitro and in vivo studies	8
Preparation and characterization of hydroxyapatite nanoparticles doped with nickel, tin, and molybdate ions for their antimicrobial effects	8
Comparative study of novel green UV-spectrophotometric platforms for simultaneous rapid analysis of flumethasone pivalate and clioquinol in their combined formulation	8
Development of UV–visible spectrophotometric methods for the quantitative andin silicostudies for cilazapril optimized by response surface methodology	8
Fabrication and characterization of dissolving microneedles for transdermal drug delivery of allopurinol	8
Design and optimization of a probiotic tablet for gastrointestinal tolerance by a simplex-centroid mixture	8
Application of HPMC HME polymer as hot melt extrusion carrier in carbamazepine solid dispersion	8
Sirolimus-exuding core-shell nanofibers as an implantable carrier for breast cancer therapy: preparation, characterization, in vitro cell studies, and in vivo anti-tumor activity	8
Biosynthesis of silver nanoparticles using Citrus hystrix leaf extract and evaluation of its anticancer efficacy against HeLa cell line	8
Topical delivery of pluronic F127/TPGS mixed micelles-based hydrogel loaded with glycyrrhizic acid for atopic dermatitis treatment	7
The potential of intranasal delivery of nanocrystals in powder form on the improvement of zaleplon performance: in-vitro, in-vivo assessment	7

One-pot synthesis of Eu-MOFs for bioimaging and drug delivery	7
Study on the mechanism of treating COVID-19 with Shenqi Wan based on network pharmacology	7
Reckoning γ-Glutamyl-S-allylcysteine as a potential main protease (mpro) inhibitor of novel SARS-CoV-2 virus identified using docking and molecular dynamics simulation	7
Development and characterization of ibuprofen co-crystals granules prepared via fluidized bed granulation in a one-step process – a design of experiment approach	7
Toward simplified oral lipid-based drug delivery using mono-/di-glycerides as single component excipients	7
Matrix metalloproteinase enzyme responsive delivery of 5-Fluorouracil using Collagen-I peptide functionalized Dendrimer-Gold nanocarrier	7
In vitroandin vivoactivity of thermosensitive liposomes loaded with doxorubicin and cisplatin	7
In-vitro and in-vivo evaluation of taste-masked ibuprofen formulated in oral dry emulsions	7
Development of piperine nanoemulsions: an alternative topical application for hypopigmentation	7
Preparation, characterization and in-Vitro/in-Vivo evaluation of meloxicam extruded pellets with enhanced bioavailability and stability	7
In vitro characterization of tofacitinib loaded novel nanoemulgel for topical delivery for the management of rheumatic arthritis	7
Smart UV-spectrophotometric platforms for rapid green analysis of miconazole nitrate and nystatin in their combined suppositories and in vitro dissolution testing	7
Crystal engineering of valproic acid and carbamazepine to improve hygroscopicity and dissolution profile	7
Fabrication and analysis of chitosan oligosaccharide based mucoadhesive patch for oromucosal drug delivery	6
Development of self-microemulsifying lipid-based formulations of trans-resveratrol by systematically constructing lipid-surfactant-water phase diagrams using long-chain lipids	6
Applicability of Raman and near-infrared spectroscopy in the monitoring of freeze-drying injectable ibuprofen	6
Enhanced full-thickness wound healing viaSophora gibbosaextract delivery based on a chitosan/gelatin dressing incorporating microemulsion	6
Are European marketed acyclovir 5% cream products similar? Comparison with EU and US reference product	6
Novel risperidone orally disintegrating minitablets for pediatric use: patient acceptance and dose adjustment	6
Glibenclamide–malonic acid cocrystal with an enhanced solubility and bioavailability	6
Optimized preparation of eugenol microcapsules and its effect on hepatic steatosis in HepG2 cells	6
Development and evaluation of a novel methotrexate-loaded electrospun patch to alleviate psoriasis plaques	6
Modulation of gene expression by thymoquinone conjugated zinc oxide nanoparticles arrested cell cycle, DNA damage and increased apoptosis in triple negative breast cancer cell line MDA-MB-231	6
Fabrication of gelatin/silk fibroin/phage nanofiber scaffold effective against multidrug resistantPseudomonas aeruginosa	6
Nanostructured lipid carriers for enhanced in vitro and in vivo schistosomicidal activity of praziquantel: effect of charge	6
Preparation and in vitro/in vivo evaluation of a clonidine hydrochloride drug–resin suspension as a sustained-release formulation	6
Solubility determination and solution thermodynamics of olmesartan medoxomil in (PEG-400 + water) cosolvent mixtures	6
New stability chiral RP-HPLC method for degradation products determination in midodrine hydrochloride	6
Nanosuspension coated multiparticulates for controlled delivery of albendazole	6
Intra-articular formulation of colchicine loaded nanoemulsion systems for enhanced locoregional drug delivery: in vitro characterization, 99mTc coupling and in vivo biodistrib	6
Physicochemical characterization of dapagliflozin and its solid-state behavior in stress stability test	6
Fabrication of a dual stimuli-responsive magnetic nanohydrogel for delivery of anticancer drugs	6
Preparation and evaluation of liposome with ropivacaine ion-pairing in local pain management	6
Preformulation studies of thymopentin: analytical method development, physicochemical properties, kinetic degradation investigations and formulation perspective	6
Development and characterization of pluronic lecithin organogel containing fluocinolone acetonide	6
Hepatoprotective effects ofPsidium guajavaon mitochondrial enzymes and inflammatory markers in carbon tetrachloride-induced hepatotoxicity	5
Characterization, in vitro dissolution, and pharmacokinetics of different batches of efavirenz raw materials	5
Impact of the functional coating of silver nanoparticles on their in vivo performance and biosafety	5
Network pharmacology prediction and molecular docking-based strategy to explore the pharmacodynamic substances and mechanism of “Mung Bean” against bacterial infection	5
Chitosan based controlled release drug delivery of mycophenolate mofetil loaded in nanocarriers system: synthesis and in-vitro evaluation	5
Investigating crystallization tendency, miscibility, and molecular interactions of drug–polymer systems for the development of amorphous solid dispersions	5
Effect of mechanochemical inclusion of triamterene into sulfobutylether-β-cyclodextrin and its improved dissolution behavior	5
EthoLeciplex: a new tool for effective cutaneous delivery of minoxidil	5
Influence of hydrotrope on solubility and bioavailability of curcumin: its complex formation and solid-state characterization	5
Enhancement of oral bioavailability and anti-colitis effect of luteolin-loaded polymer micelles with RA (rosmarinic acid)-SS-mPEG as carrier	5
Brigatinib loaded poly(d,l-lactide-co-glycolide) nanoparticles for improved anti-tumoral activity against non-small cell lung cancer cell lines	5
A comparative study of consistency between Paeonia rubra hort traditional decoction and dispensing granule decoctions from different sources	5
Structure activity evaluation and computational analysis identify potent, novel 3-benzylidene chroman-4-one analogs with anti-fungal, anti-oxidant, and anti-cancer activities	5
Design and evaluation of hyaluronic acid-coated PLGA nanoparticles of raloxifene hydrochloride for treatment of breast cancer	5
Applications of bio-predictive dissolution tools for the development of solid oral dosage forms: current industry experience	5
Amphotericin B liposomal formulation: applicable preparation methods, challenges, and tips	5
Nanostructured polyelectrolyte complexes based on chitosan and sodium alginate containing rifampicin for the potential treatment of tuberculosis	5
Implantable drug delivery systems for the treatment of osteomyelitis	5
Mapping the technological landscape of SARS, MERS, and SARS-CoV-2 vaccines	5
Comparison of the performance of two grades of metformin hydrochloride elaboration by means of the SeDeM system, compressibility, compactability, and process capability indices	5
Synthesis and characterization of magnetic Ag–Fe 3 O 4 @polymer hybrid nanocomposite systems with promising antibacterial applicat	5
Effectual nanotherapy against oral squamous cell carcinoma	5
Ocular delivery of sunitinib-loaded nanoparticles doped in tragacanthic acid hydrogel in treatment of diabetic retinopathy in rats	5
Transferrin decorated PLGA encumbered moxifloxacin nanoparticles andin vitrocellular studies	5
Formulation and in vitro and in vivo evaluation of surfactant-stabilized mucoadhesive nanogels for vaginal delivery of fluconazole	5
Development and greenness assessment of a stability-indicating HPLC-DAD method for simultaneous determination of allopurinol and benzbromarone	5
Experimental measurement – correlation of solubility and dissolution thermodynamics study of itraconazole in pure monosolvents at various temperatures	5
Evaluation of tissue-clearing techniques for intraorgan imaging of distribution of polymeric nanoparticles as drug carriers	5
Effects of different air change rates on cleanroom ‘in operation’ status	4
Preparation and characterization of triamterene complex with ascorbic acid derivatives	4
Dual-targeted delivery system using hollow silica nanoparticles with H + -triggered bubble generating characteristic coated with hyaluronic acid and AS1411 for cance	4
A multistage oral delivery system of PTX for improving oral bioavailability and enhancing anticancer efficacy	4
Multi-sensitive curcumin-loaded nanomicelle based on ABC-CBA block copolymer for sustained drug delivery	4
Insight of the variousin silicoscreening techniques developed for assortment of cocrystal formers and their thermodynamic characterization	4
Study on the taste-masking effect and mechanism of Acesulfame K on berberine hydrochloride	4
Formulation, biopharmaceutical evaluation and in-vitro screening of polyherbal phytosomes for breast cancer therapy	4
Ecofriendly phytosynthesized zirconium oxide nanoparticles as antibiofilm and quorum quenching agents against Acinetobacter baumannii	4
The nano-based theranostics for respiratory complications of COVID-19	4
Temozolomide nano-in-nanofiber delivery system with sustained release and enhanced cellular uptake by U87MG cells	4
Development of bifunctional vaginal suppositories by joint use terconazole and probiotic for treatment and prophylaxis of vulvovaginal candidiasis	4
Choline and PEG dually modified artemether nano delivery system targeting intra-erythrocytic Plasmodium and its pharmacodynamics in vivo	4
Effect of roll compaction pressure on the properties of high drug-loaded piracetam granules and tablets	4
Preparation, in vitro and in vivo evaluation of pinocembrin-loaded TPGS modified liposomes with enhanced bioavailability and antihyperglycemic activity	4
Development of purified cashew gum mucoadhesive buccal tablets containing nystatin for treatment of oral candidiasis	4
Preparation and evaluation of oral self-microemulsifying drug delivery system of Chlorophyll	4

Curcumin-loaded microemulsion: formulation, characterization, and in vitro skin penetration	4
DSPE-PEG polymers for improving pulmonary absorption of poorly absorbed macromolecules in rats and relative mechanism	4
Formulation and optimization of silymarin-encapsulated binary micelles for enhanced amyloid disaggregation activity	4
In vitroenzyme inhibition andin vivoanti-hyperuricemic potential of eugenol: an experimental approach	4
Bicyclol alleviates high-fat diet-induced hepatic ER stress- and autophagy-associated non-alcoholic fatty liver disease/non-alcoholic steatohepatitis in mice	4
Ibuprofen-loaded centrifugally spun microfibers for quick relief of inflammation in rats	4
Development of herpetrione nanosuspensions stabilized by glycyrrhizin for enhancing bioavailability and synergistic hepatoprotective effect	4
Design and fabrication of Sesamol-loaded transfersomal gel for wound healing: physicochemical characterization and in-vivo evaluation	4
Synthesis of novel combinatorial drug delivery system (nCDDS) for co-delivery of 5-fluorouracil and leucovorin calcium for colon targeting and controlled drug release	4
Influence of chitosan thioglycolic acid conjugate in improving bioavailability of an antiparkinson drug; Rasagiline Mesylate from transdermal patch	4
Development of pediatric orally disintegrating mini-tablets containing atomoxetine hydrochloride-β-cyclodextrin inclusion complex using experimental design	4
Aloe vera and artemisia vulgaris hydrogels: exploring the toxic effects of structural transformation of the biocompatible materials	3
Preparation and evaluation of sublingual film of ketorolac tromethamine	3
Multifunctional nanoparticles encapsulating methotrexate and curcumin for holistic management of rheumatoid arthritis: in-vitro and pre-clinical assessment	3
Hydrophobic ion pairing with cationic derivatives of α-, ß-, and γ-cyclodextrin as a novel approach for development of a self-nano-emulsifying drug delivery system (SNEDDS) for oral delivery of hepari	3
Shellac- a natural carrier for colon targeting of indomethacin using hot melt extrusion	3
Spray dried nanospheres for inclusion complexes of cefpodoxime proxetil with β-cyclodextrin, 2-hydroxypropyl-β-cyclodextrin and methyl-β-cyclodextrin: improved dissolution and enhanced antibacterial a	3
Investigating the fate and toxicity of green synthesized gold nanoparticles in albino mice	3
A review of twin screw wet granulation mechanisms in relation to granule attributes	3
Preparation and characterization of aqueous vitamin E/Soluplus® dispersions for film coating applications	3
In silicomolecular docking for assessing anti-fungal competency of hydroxychavicol, a phenolic compound of betel leaf (Piper betleL.) against COVID-19 associated maiming mycotic infectio	3
Visualizing fluid transport inside orally disintegrating tablets and changes in tablets using real-time X-ray radiography and X-ray computed tomography	3
A sensitive and high-throughput LC-ESI-MS/MS method to detect budesonide in human plasma: application to an evaluation of pharmacokinetics of budesonide intranasal formulations with and without charco	3
Chitosan-coated alginate (CCA) nanoparticles for augmentation of topical antihistaminic activity of diphenhydramine:in-vitrooptimization, skin histopathology and pharmacodynamic studies with in	3
Multiobjective nonlinear model predictive control of pharmaceutical batch crystallizers	3
Co-encapsulation of metformin and ginger into the liposomes: in vitro characterization and in vivo anti-psoriasis evaluation	3
Oral formulation of Prussian blue with improved efficacy for prophylactic use against thallium	3
Study on co-delivery of pemetrexed disodium and Bcl-2 siRNA by poly-γ-glutamic acid-modified cationic liposomes for the inhibition of NSCLC	3
Crisaborole loaded nanoemulgel for the mitigation of atopic dermatitis in mice model	3
Fabrication of pH responsive hydrogel blends of chondroitin sulfate/pluronic F-127 for the controlled release of ketorolac: its characterization and acute oral toxicity study	3
Curcuma comosa loaded transfersomal gel for transdermal application: formulation, in vitro and in vivo evaluation	3
The mechanisms of immune-chemotherapy with nanocomplex codelivery of pTRP-2 and adjuvant of paclitaxel against melanoma	3
Multivesicular liposomal depot system for sustained delivery of risperidone: development, characterization, and toxicity assessment	3
Nasal residence time and rheological properties of a new bentonite-based thixotropic gel emulsion nasal spray – AM-301	3
Preparation and characterization of itraconazole loaded nanomicelles based on dextran–behenic acid for cutaneous leishmaniasis treatment	3
Boron phenyl alanine targeted chitosan–PNIPAAm core–shell thermo-responsive nanoparticles: boosting drug delivery to glioblastoma in BNCT	3
Budesonide-liposomes inclusion complex in thermosensitive gel alleviates DSS-induced ulcerative colitis in mice	3
Ginsenoside Rg3 liposomes regulate tumor microenvironment for the treatment of triple negative breast cancer	3
Synergistic effects of quercetin-loaded CoFe 2 O 4 @Liposomes regulate DNA damage and apoptosis in MCF-7 cancer cells: based on bi	3
Dual-drug amorphous formulation of gliclazide	3
The potential of ODFs as carriers for drugs/vaccines against COVID-19	3
Targeted delivery of epirubicin to breast cancer cells using poly-aptamer DNA nanocarriers prepared by the RCA method with multiple repeats of aptamers of FOXM1 and AS1411	3
Multivariate analysis for optimization and validation of the industrial tablet-manufacturing process	3
Polymer-based prolonged-release nanoformulation of duloxetine: fabrication, characterization and neuropharmacological assessments	3
Exploring the influence factors and improvement strategies of drug polymorphic transformation combined kinetic and thermodynamic perspectives during the formation of nanosuspensions	3
Solid state characterization, solubility, intrinsic dissolution and stability behavior of allopurinol hydrochloride salt	3
Improved anti-inflammatory effect of curcumin by designing self-emulsifying drug delivery system	3
Incentives to promote the US pharmaceutical innovation: empirical research based on the case of Epogen	3
Efficient drug development of oseltamivir capsules based on process control, bioequivalence and PBPK modeling	3
Eutectic solutions for healing: a comprehensive review on therapeutic deep eutectic solvents (TheDES)	3
Development and validation of HPLC method for simultaneous determination of Leflunomide and folic acid in the nanoparticulate system by reversed-phase HPLC	3
Preparation and optimization of multi-functional directly compressible excipient: an integrated approach of principal component analysis and design of experiments	3
Formulation and rheological evaluation of liposomes-loaded carbopol hydrogels based on thermal waters	3
Bone regeneration in rat using polycaprolactone/gelatin/epinephrine scaffold	3
Preparation and in vitro/in vivo evaluation of a self-microemulsifying drug delivery system containing chrysin	3
Development and validation of LC/MS method for the determination of meclizine enantiomers in pharmaceutical formulations	3
Design and development of donepezil hydrochloride loaded nanostructured lipid carriers for efficient management of Alzheimer’s disease	3
Exploration of polymethacrylate and Hypromellose for the development of a non-sulfhydryl ACE inhibitor mucoadhesive system using Box-Behnken design: in-vitro and ex-vivo evaluation	3
Pharmacokinetic and pharmacodynamic studies of iloperidone-loaded lipid nanoemulsions via oral route of administration	3
Microneedles assisted controlled and improved transdermal delivery of high molecular drugs viain situforming depot thermoresponsive poloxamers gels in skin microchannels	3