American Journal of Physiology-Cell Physiology

Papers
(The TQCC of American Journal of Physiology-Cell Physiology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Adipose tissue inflammation and metabolic dysfunction in obesity489
Decoding SARS-CoV-2 hijacking of host mitochondria in COVID-19 pathogenesis235
Long-term complications of COVID-19192
A brief history of organoids178
Mitochondrial metabolic manipulation by SARS-CoV-2 in peripheral blood mononuclear cells of patients with COVID-19139
Purinergic signaling, DAMPs, and inflammation121
Exosomes derived from mmu_circ_0000250-modified adipose-derived mesenchymal stem cells promote wound healing in diabetic mice by inducing miR-128-3p/SIRT1-mediated autophagy117
Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism88
Long non-coding RNA MALAT1 promotes angiogenesis and immunosuppressive properties of HCC cells by sponging miR-14073
The H+-ATPase (V-ATPase): from proton pump to signaling complex in health and disease70
The kynurenine connection: how exercise shifts muscle tryptophan metabolism and affects energy homeostasis, the immune system, and the brain62
In vitro and ex vivo models of adipocytes62
Single-cell transcriptomic analysis identifies extensive heterogeneity in the cellular composition of mouse Achilles tendons62
Aquaporin-3 in the epidermis: more than skin deep61
Extracellular matrix dynamics in vascular remodeling60
Depletion of resident muscle stem cells negatively impacts running volume, physical function, and muscle fiber hypertrophy in response to lifelong physical activity60
Neuroendocrine signaling in the skin with a special focus on the epidermal neuropeptides52
Molecular nature and physiological role of the mitochondrial calcium uniporter channel51
Extracellular vesicles as signaling mediators in type 2 diabetes mellitus50
Wound healing and fibrosis: a contrasting role for periostin in skin and the oral mucosa49
The CC and CXC chemokines: major regulators of tumor progression and the tumor microenvironment48
Neutrophil heterogeneity and fate in inflamed tissues: implications for the resolution of inflammation48
Stem cells and lung regeneration46
H2S as a potential defense against COVID-19?45
The intersection of metformin and inflammation44
Tenascin-C in cardiac disease: a sophisticated controller of inflammation, repair, and fibrosis44
Soluble ACE2 as a potential therapy for COVID-1942
Is REDD1 a metabolic double agent? Lessons from physiology and pathology38
Conjunction junction, what’s the function? CCN proteins as targets in fibrosis and cancers38
Heterogeneity within molecular subtypes of breast cancer38
The vitamin D receptor regulates mitochondrial function in C2C12 myoblasts37
Drivers of dynamic intratumor heterogeneity and phenotypic plasticity36
Integrative view of serpins in health and disease: the contribution of serpinA335
Hydrogen sulfide rescues high glucose-induced migration dysfunction in HUVECs by upregulating miR-126-3p34
Cellular metabolomics of pulmonary fibrosis, from amino acids to lipids33
Mitochondrial redox regulation and myocardial ischemia-reperfusion injury33
Extracellular vesicle secretion is tissue-dependent ex vivo and skeletal muscle myofiber extracellular vesicles reach the circulation in vivo33
Irradiation-induced senescence of bone marrow mesenchymal stem cells aggravates osteogenic differentiation dysfunction via paracrine signaling33
Microglia depletion exacerbates acute seizures and hippocampal neuronal degeneration in mouse models of epilepsy31
Advances in aquaporin-2 trafficking mechanisms and their implications for treatment of water balance disorders29
ARF family GTPases with links to cilia29
Upregulating microRNA-874-3p inhibits CXCL12 expression to promote angiogenesis and suppress inflammatory response in ischemic stroke29
More than a cell biosensor: aryl hydrocarbon receptor at the intersection of physiology and inflammation28
Factors mediating spaceflight-induced skeletal muscle atrophy28
The glycosaminoglycan interactome 2.028
Muscle-nerve communication and the molecular assessment of human skeletal muscle denervation with aging28
Long noncoding RNA Kcnq1ot1 promotes sC5b-9-induced podocyte pyroptosis by inhibiting miR-486a-3p and upregulating NLRP328
Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension27
Cell physiology and molecular mechanism of anion transport by erythrocyte band 3/AE127
Mitochondria-cytokine crosstalk following skeletal muscle injury and disuse: a mini-review27
The role of lamina cribrosa tissue stiffness and fibrosis as fundamental biomechanical drivers of pathological glaucoma cupping27
Heterogeneous groups of alveolar type II cells in lung homeostasis and repair27
TNFα and IL-17 alkalinize airway surface liquid through CFTR and pendrin27
Role of glypican-1 in regulating multiple cellular signaling pathways27
Translating the force—mechano-sensing GPCRs26
The olfactory G protein-coupled receptor (Olfr-78/OR51E2) modulates the intestinal response to colitis26
LncRNA GAS5 inhibits miR-579-3p to activate SIRT1/PGC-1α/Nrf2 signaling pathway to reduce cell pyroptosis in sepsis-associated renal injury26
New aspects of hepatic endothelial cells in physiology and nonalcoholic fatty liver disease25
TRPV4-Rho signaling drives cytoskeletal and focal adhesion remodeling in trabecular meshwork cells25
Thrombospondin-1 in maladaptive aging responses: a concept whose time has come24
Breast cancer-associated skeletal muscle mitochondrial dysfunction and lipid accumulation is reversed by PPARG24
Monocyte recruitment and fate specification after myocardial infarction24
Aerobic exercise and resistance exercise alleviate skeletal muscle atrophy through IGF-1/IGF-1R-PI3K/Akt pathway in mice with myocardial infarction24
LncRNA GAS5 attenuates fibroblast activation through inhibiting Smad3 signaling24
Engineering fiber anisotropy within natural collagen hydrogels23
Disuse-induced skeletal muscle atrophy in disease and nondisease states in humans: mechanisms, prevention, and recovery strategies23
Mitochondrial DNA damage as driver of cellular outcomes22
Macrophages in myocardial infarction22
Out of breath, out of time: interactions between HIF and circadian rhythms22
Alamandine enhances cardiomyocyte contractility in hypertensive rats through a nitric oxide-dependent activation of CaMKII22
The role of the sphingolipid pathway in liver fibrosis: an emerging new potential target for novel therapies22
miRNA degradation in the mammalian brain22
Osteoclast-derived exosomal let-7a-5p targets Smad2 to promote the hypertrophic differentiation of chondrocytes22
Recent advances in understanding cancer-associated fibroblasts in pancreatic cancer22
Cardiac tissue remodeling in healthy aging: the road to pathology22
A glitch in the matrix: the pivotal role for extracellular matrix remodeling during muscle hypertrophy22
Role of SERCA and sarcolipin in adaptive muscle remodeling22
Sequential paracrine mechanisms are necessary for the therapeutic benefits of stem cell therapy22
Mitochondrial quality surveillance: mitophagy in cardiovascular health and disease22
Control of coronary vascular resistance by eicosanoids via a novel GPCR21
Assessment of the effects of Syk and BTK inhibitors on GPVI-mediated platelet signaling and function21
Resolution of inflammation in immune and nonimmune cells by interleukin-1921
Regulatory networks coordinating mitochondrial quality control in skeletal muscle21
The CD38 glycohydrolase and the NAD sink: implications for pathological conditions21
Characterization of cellular oxidative stress response by stoichiometric redox proteomics21
Sex omission and male bias are still widespread in cell experiments21
Proteasome inhibition in multiple myeloma: lessons for other cancers20
G protein-coupled receptor signaling: transducers and effectors20
Electrically stimulated contractile activity-induced transcriptomic responses and metabolic remodeling in C2C12 myotubes: twitch vs. tetanic contractions20
Aquaporin water channels as regulators of cell-cell adhesion proteins20
Bioenergetics underlying single-cell migration on aligned nanofiber scaffolds20
“SLC-omics” of the kidney: solute transporters along the nephron20
3-Mercaptopyruvate sulfurtransferase/hydrogen sulfide protects cerebral endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury via mitoprotection and inhibition of the RhoA/20
Actin dynamics as critical ion channel regulator: ENaC and Piezo in focus20
Exploring mechanistic links between extracellular branched-chain amino acids and muscle insulin resistance: an in vitro approach19
Mitochondrial transplantation in cardiomyocytes: foundation, methods, and outcomes19
Aquaporin-5 regulation of cell–cell adhesion proteins: an elusive “tail” story19
Mechanisms of exercise as a preventative measure to muscle wasting19
Recent progress in assays for GPCR drug discovery19
The importance of mitochondrial quality control for maintaining skeletal muscle function across health span19
GPCR systems pharmacology: a different perspective on the development of biased therapeutics19
LRRC8A homohexameric channels poorly recapitulate VRAC regulation and pharmacology19
Suppression of long noncoding RNA MALAT1 inhibits the development of uveal melanoma via microRNA-608-mediated inhibition of HOXC419
Knockdown of the E3 ubiquitin ligase UBR5 and its role in skeletal muscle anabolism19
The microRNA-29 family: role in metabolism and metabolic disease19
WNKs are potassium-sensitive kinases19
Mechanisms and mathematical modeling of ROS production by the mitochondrial electron transport chain19
Generation and optimization of highly pure motor neurons from human induced pluripotent stem cells via lentiviral delivery of transcription factors19
Diseases caused by mutations in the Na+/K+ pump α1 gene ATP1A118
Role of oxygen in fetoplacental endothelial responses: hypoxia, physiological normoxia, or hyperoxia?18
Role of metaplasia during gastric regeneration18
The emerging role of MEIS1 in cell proliferation and differentiation18
Protein biomarkers in breast cancer-derived extracellular vesicles for use in liquid biopsies18
The essential role of intraflagellar transport protein IFT81 in male mice spermiogenesis and fertility18
Serum extracellular vesicle miR-203a-3p content is associated with skeletal muscle mass and protein turnover during disuse atrophy and regrowth18
NAD+ precursors protect corneal endothelial cells from UVB-induced apoptosis18
LDL induces cholesterol loading and inhibits endothelial proliferation and angiogenesis in Matrigels: correlation with impaired angiogenesis during wound healing18
Let-7d-5p suppresses inflammatory response in neonatal rats with necrotizing enterocolitis via LGALS3-mediated TLR4/NF-κB signaling pathway18
Sex-specific adaptations to high-salt diet preserve electrolyte homeostasis with distinct sodium transporter profiles17
Different modalities of host cell death and their impact onMycobacterium tuberculosisinfection17
Next-generation inward rectifier potassium channel modulators: discovery and molecular pharmacology17
Coreceptor functions of cell surface heparan sulfate proteoglycans17
Identification and characterization of Fbxl22, a novel skeletal muscle atrophy-promoting E3 ubiquitin ligase17
Indoxyl sulfate impairs angiogenesis via chronic aryl hydrocarbon receptor activation17
MicroRNA-195 regulates Tuft cell function in the intestinal epithelium by altering translation of DCLK117
The role of phospholamban and GSK3 in regulating rodent cardiac SERCA function17
Milk exosomes in nutrition and drug delivery17
Bioprinting stem cells: building physiological tissues one cell at a time17
Burn-induced hypermetabolism and skeletal muscle dysfunction17
WNK3 and WNK4 exhibit opposite sensitivity with respect to cell volume and intracellular chloride concentration17
Epigenetic evidence for distinct contributions of resident and acquired myonuclei during long-term exercise adaptation using timed in vivo myonuclear labeling17
Skeletal muscle progenitors are sensitive to collagen architectural features of fibril size and cross linking16
Recent progress on surfactant protein A: cellular function in lung and kidney disease development16
Global changes to HepG2 cell metabolism in response to galactose treatment16
Nonclassical monocytes in cardiovascular physiology and disease16
Rho GTPases and the emerging role of tunneling nanotubes in physiology and disease16
Neuronal G protein-gated K+ channels16
The septate junction protein Mesh is required for epithelial morphogenesis, ion transport, and paracellular permeability in theDrosophilaMalpighian tubule16
Super-relaxed state of myosin in human skeletal muscle is fiber-type dependent16
Changes in endothelial glycocalyx layer protective ability after inflammatory stimulus16
Coordinated alpha-crystallin B phosphorylation and desmin expression indicate adaptation and deadaptation to resistance exercise-induced loading in human skeletal muscle15
Barriers and opportunities for gemcitabine in pancreatic cancer therapy15
Immunoengineering approaches for cytokine therapy15
A semiautomated measurement of muscle fiber size using the Imaris software15
Chloride transport modulators as drug candidates15
Spatiotemporal diversity and regulation of glycosaminoglycans in cell homeostasis and human disease15
Murine models of Duchenne muscular dystrophy: is there a best model?15
Advances in the development of novel compounds targeting cation-chloride cotransporter physiology15
Mitochondrial stress responses in Duchenne muscular dystrophy: metabolic dysfunction or adaptive reprogramming?15
Notch enhances Ca2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K+ channels15
Potassium channels in intestinal epithelial cells and their pharmacological modulation: a systematic review15
MiR-4674 regulates angiogenesis in tissue injury by targeting p38K signaling in endothelial cells15
Discovery of thymosin β4 as a human exerkine and growth factor15
Overlapping and distinct biological effects of IL-6 classic and trans-signaling in vascular endothelial cells14
The role of Cland K+efflux in NLRP3 inflammasome and innate immune response activation14
Female sex and Western-style diet protect mouse resistance arteries during acute oxidative stress14
Coordinate adaptations of skeletal muscle and kidney to maintain extracellular [K+] during K+-deficient diet14
Recent advances in measuring and understanding the regulation of exercise-mediated protein degradation in skeletal muscle14
Proteolysis: a key post-translational modification regulating proteoglycans14
Circulating miRNAs associated with nonalcoholic fatty liver disease14
The septate junction protein Tetraspanin 2A is critical to the structure and function of Malpighian tubules inDrosophila melanogaster14
The cellular and molecular basis of in vivo synaptic plasticity in rodents14
Procoagulant platelets: novel players in thromboinflammation14
Skeletal muscle wasting: the estrogen side of sexual dimorphism14
From initial segment to cauda: a regional characterization of mouse epididymal CD11c+ mononuclear phagocytes based on immune phenotype and function14
Microfluidic confinement enhances phenotype and function of hepatocyte spheroids14
TRPV1 activation stimulates NKCC1 and increases hydrostatic pressure in the mouse lens14
Bioinspired in vitro microenvironments to control cell fate: focus on macromolecular crowding14
Hypoxia-inducible factor-1 mediates pancreatic β-cell dysfunction by intermittent hypoxia14
Hypoxia-inducible factor as a bridge between healthy barrier function, wound healing, and fibrosis14
Inhibition of miR-155 potentially protects against lipopolysaccharide-induced acute lung injury through the IRF2BP2-NFAT1 pathway13
Hyaluronan in pathophysiology of vascular diseases: specific roles in smooth muscle cells, endothelial cells, and macrophages13
Junctional sarcoplasmic reticulum motility in adult mouse ventricular myocytes13
Oncosuppressive roles of decorin through regulation of multiple receptors and diverse signaling pathways13
Chaperone-mediated autophagy protects cardiomyocytes against hypoxic-cell death13
Moving human muscle physiology research forward: an evaluation of fiber type-specific protein research methodologies13
KATP channels in lymphatic function13
Ca2+dependency of limb muscle fiber contractile mechanics in young and older adults13
Novel HIF-1-target gene isthmin1 contributes to hypoxia-induced hyperpermeability of pulmonary microvascular endothelial cells monolayers13
The role of mitochondria in the pathophysiology and treatment of common metabolic diseases in humans13
Adaptive and maladaptive roles of lipid droplets in health and disease13
Synemin-related skeletal and cardiac myopathies: an overview of pathogenic variants13
TRPV1 activation mitigates hypoxic injury in mouse cardiomyocytes by inducing autophagy through the AMPK signaling pathway13
The regulation of polyamine pathway proteins in models of skeletal muscle hypertrophy and atrophy: a potential role for mTORC113
Suppression of lncRNA HOTAIR alleviates RCC angiogenesis through regulating miR-126/EGFL7 axis13
Aggrecan and versican: two brothers close or apart13
Plasminogen activator receptor assemblies in cell signaling, innate immunity, and inflammation13
Mechanosensitive myosin II but not cofilin primarily contributes to cyclic cell stretch-induced selective disassembly of actin stress fibers13
miR-19b-3p is associated with a diametric response to resistance exercise in older adults and regulates skeletal muscle anabolism via PTEN inhibition13
The effect of young and old ex vivo human serum on cellular protein synthesis and growth in an in vitro model of aging12
The β1-integrin plays a key role in LEC invasion in an optimized 3-D collagen matrix model12
Mitochondrial ion channels in cardiac function12
Pituitary adenylate cyclase-activating polypeptide-induced PAC1 receptor internalization and recruitment of MEK/ERK signaling enhance excitability of dentate gyrus granule cells12
lncRNAs in T lymphocytes: RNA regulation at the heart of the immune response12
Ex vivo use of cell-permeable succinate prodrug attenuates mitochondrial dysfunction in blood cells obtained from carbon monoxide-poisoned individuals12
CD47 and thrombospondin-1 regulation of mitochondria, metabolism, and diabetes12
Downregulation of AAA-domain-containing protein 2 restrains cancer stem cell properties in esophageal squamous cell carcinoma via blockade of the Hedgehog signaling pathway12
Brefeldin A and kifunensine modulate LPS-induced lung endothelial hyperpermeability in human and bovine cells12
Role of platelets in regulating activated coagulation factor XI activity12
Active modulation of human erythrocyte mechanics12
MicroRNA-99b-5p downregulates protein synthesis in human primary myotubes11
Nicotinamide N-methyltransferase upregulation via the mTORC1-ATF4 pathway activation contributes to palmitate-induced lipotoxicity in hepatocytes11
Caveolin-1 stabilizes ATP7A, a copper transporter for extracellular SOD, in vascular tissue to maintain endothelial function11
Impaired glucose partitioning in primary myotubes from severely obese women with type 2 diabetes11
Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance-related vascular damage11
Emerging roles of calcium-sensing receptor in the local regulation of intestinal transport of ions and calcium11
Effect of luminal flow on doming of mpkCCD cells in a 3D perfusable kidney cortical collecting duct model11
Glycosaminoglycans in cancer therapy11
Role of proton-activated G protein-coupled receptors in pathophysiology11
Syncytialization alters the extracellular matrix and barrier function of placental trophoblasts11
ALY688 elicits adiponectin-mimetic signaling and improves insulin action in skeletal muscle cells11
Reversing mitochondrial defects in aged hearts: role of mitochondrial calpain activation11
Transforming nanobodies into high-precision tools for protein function analysis11
Mechanisms of altered skeletal muscle action potentials in the R6/2 mouse model of Huntington’s disease10
Dystrophin-negative slow-twitch soleus muscles are not susceptible to eccentric contraction induced injury over the lifespan of the mdx mouse10
Kir5.1 channels: potential role in epilepsy and seizure disorders10
Myristoylated alanine-rich C kinase substrate-like protein-1 regulates epithelial sodium channel activity in renal distal convoluted tubule cells10
Protective and anti-inflammatory effects of acetylcholine in the heart10
Manipulation of the miR-378a/mt-ATP6 regulatory axis rescues ATP synthase in the diabetic heart and offers a novel role for lncRNA Kcnq1ot110
Identification of variants of ISL1 gene promoter and cellular functions in isolated ventricular septal defects10
MicroRNA-145 suppresses gastric cancer progression by targeting Hu-antigen R10
Glucose-induced, duration-dependent genome-wide DNA methylation changes in human endothelial cells10
Inwardly rectifying K+ channels 4.1 and 5.1 (Kir4.1/Kir5.1) in the renal distal nephron10
Role of complement 3 in renin generation during the differentiation of mesenchymal stem cells to smooth muscle cells10
Effect of rapamycin on mitochondria and lysosomes in fibroblasts from patients with mtDNA mutations10
miR-135b-dependent downregulation of S100B promotes neural stem cell differentiation in a hypoxia/ischemia-induced cerebral palsy rat model10
Loss of calpains-1 and -2 prevents repair of plasma membrane scrape injuries, but not small pores, and induces a severe muscular dystrophy10
Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature10
Exercise mitigates the Toll of muscle atrophy: a narrative review of the effects of exercise on Toll-like receptor-4 in leukocytes and skeletal muscle10
The mechanobiome: a goldmine for cancer therapeutics10
Skeletal tissue regulation by catalase overexpression in mitochondria10
The ocular pulse decreases aqueous humor outflow resistance by stimulating nitric oxide production10
TRIM59 inhibits PPM1A through ubiquitination and activates TGF-β/Smad signaling to promote the invasion of ectopic endometrial stromal cells in endometriosis10
Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity10
Role of glycolysis in the development of atherosclerosis10
β2 integrin activation and signal transduction in leukocyte recruitment10
Dynamics and mechanistic underpinnings to pharmacology of class A GPCRs: an NMR perspective9
Downregulation of the Ca2+-activated K+ channel KCa3.1 in mouse preosteoblast cells treated with vitamin D receptor agonist9
Role of hepatic lipid species in the progression of nonalcoholic fatty liver disease9
Vessel-on-a-chip models for studying microvascular physiology, transport, and function in vitro9
Targeting syndecan-1: new opportunities in cancer therapy9
Effect of the ketogenic diet in excitable tissues9
Inhibiting fusion with cellular membrane system: therapeutic options to prevent severe acute respiratory syndrome coronavirus-2 infection9
Essential hypertension is associated with blunted smooth muscle cell vasodilator responsiveness and is reversed by 10-20-30 training in men9
Relocation of phosphofructokinases within epithelial cells is a novel event preceding breast cancer recurrence that accurately predicts patient outcomes9
Skeletal muscle memory9
Isolation and characterization of muscle stem cells, fibro-adipogenic progenitors, and macrophages from human skeletal muscle biopsies9
Maresin-1 induces cardiomyocyte hypertrophy through IGF-1 paracrine pathway9
Kir6.1 and SUR2B in Cantú syndrome9
Isoform-specific Na,K-ATPase and membrane cholesterol remodeling in motor endplates in distinct mouse models of myodystrophy9
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