American Journal of Physiology-Heart and Circulatory Physiology

Article	Citations
Expanding the supply of donor hearts through donation after circulatory death	90
Deletion of DWORF does not affect cardiac function in aging and in PLN-R14del cardiomyopathy	73
NADPH oxidase overexpression and mitochondrial OxPhos impairment are more profound in human hearts donated after circulatory death than brain death	65
Glycoprotein 130 orchestrates signal transduction network to promote cardiomyocyte proliferation for normal growth	65
Reverse is a complicated direction	63
Mannitol and hyponatremia regulate cardiac ventricular conduction in the context of sodium channel loss of function	57
A minimally invasive swine model of chronic kidney disease-associated heart failure	52
Long-term hemodynamic responses and reverse remodeling after pharmacotherapy in HFpEF versus HFrEF: a systematic review and meta-analysis	52
Sexual dimorphism in right ventricular adaptation to pressure overload involves differential angiogenic response.	48
Sexual Dimorphism in the Downregulation of Extracellular Matrix Genes Contribute to Aortic Structural Stiffness in Female Mice	47
More than just a small left ventricle: the right ventricular fibroblast and ECM in health and disease	43
Central command-related increases in blood velocity of anterior cerebral artery and prefrontal oxygenation at the onset of voluntary tapping	42
Relationship between LDL-cholesterol, small and dense LDL particles, and mRNA expression in a cohort of African Americans	42
Reply to Schmitz	41
Metabolic theory of preeclampsia: implications for maternal cardiovascular health	38
Cell therapy attenuates endothelial dysfunction in hypertensive rats with heart failure and preserved ejection fraction	38
Ischemic damage to every segment of the oxidative phosphorylation cascade elevates ETC driving force and ROS production in cardiac mitochondria	37
One method does not fit all: the importance of sex and using multiple methods to assess cardiac reserve in mice	36
Computer modeling to predict balloon pulmonary angioplasty success	35
Accelerated atherosclerosis in beta-thalassemia	35
Comprehensive analyses of the inotropic compound omecamtiv mecarbil in rat and human cardiac preparations	34
Spring cleaning: freshening up the portfolio	34
Prenatal ethanol exposure impairs the conduction delay at the atrioventricular junction in the looping heart	33
Scratching beneath the surface: IL4Rα blockade and the progression from myocardial ischemic injury to heart failure	33
Sex differences in microvascular function and arterial hemodynamics in nondialysis chronic kidney disease	33

Reply to De Mey et al.	32
Global Reach 2018: sympathetic neural and hemodynamic responses to submaximal exercise in Andeans with and without chronic mountain sickness	30
Reply to Trimaille et al.	30
Lower hemoglobin levels associate with higher baroreflex sensitivity and heart rate variability	30
Interplay between temporal and spatial dispersion of repolarization in the initiation and perpetuation of torsades de pointes in the chronic atrioventricular block dog	29
Understanding the estrogen paradox of pulmonary arterial hypertension in the context of right ventricular function	29
Cardiovascular consequences of preeclampsia: Is the reactivity to stress the missing piece of the puzzle?	28
Chronic perinatal hypoxia delays cardiac maturation in a mouse model for cyanotic congenital heart disease	28
Innervation of adipocytes is limited in mouse perivascular adipose tissue	28
Luseogliflozin, a sodium-glucose cotransporter-2 inhibitor, reverses cerebrovascular dysfunction and cognitive impairments in 18-mo-old diabetic animals	27
Vasomotor symptoms of menopause, autonomic dysfunction, and cardiovascular disease	26
Diving deep toward the bottlenose dolphins’ antiarterial aging secret: insight for the circulating milieu as a novel mechanism to preserve endothelial health	26
Real-time in vivo thoracic spinal glutamate sensing during myocardial ischemia	26
Sex differences in the impact of parental obesity on offspring cardiac SIRT3 expression, mitochondrial efficiency, and diastolic function early in life	25
Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum	25
Hypobaric hypoxia and cardiac baroreflex sensitivity in young women	25
Exercise-induced cardiac troponin release in athletes with versus without coronary atherosclerosis	24
Reply to Blaustein et al.	24
The importance of biological sex in cardiac cachexia	24
Find the stimulus, save the heart: a heroes’ story	24
Loss of talin in cardiac fibroblasts results in augmented ventricular cardiomyocyte hypertrophy in response to pressure overload	23
Nervy Issues of Fatty Tissues: a Deeper Dig into the innervation of fat	23
Cardiac autonomic function is preserved in young adults with major depressive disorder	23
Therapy-naïve malignancy causes cardiovascular disease: a state-of-the-art cardio-oncology perspective	23
The FXYD1 protein plays a protective role against pulmonary hypertension and arterial remodeling via redox and inflammatory mechanisms	23
Partial sleep restriction and blood pressure during exercise: surprising findings and future directions	23
Slower shortening kinetics of cardiac muscle performing Windkessel work-loops increase mechanical efficiency	23
Immune interactions in pembrolizumab (PD-1 inhibitor) cancer therapy and cardiovascular complications	22
Understanding Takotsubo syndrome: first evaluate your mouse model	22
Liposomal nanocarriers of preassembled glycocalyx expeditiously restore endothelial glycocalyx in endotoxemia	22
A novel role for PGE2-EP4 in the developmental programming of the mouse ductus arteriosus: consequences for vessel maturation and function	22
Correlations between salivary- and blood-derived gonadal hormone assessments and implications for inclusion of female participants in research studies	22
Ethanol: striking the cardiovascular system by harming the gut microbiota	22
Widespread intracoronary allogeneic cardiosphere-derived cell therapy with and without cyclosporine in reperfused myocardial infarction	22
Clinical physiology: the crucial role of MRI in evaluation of peripheral artery disease	22
Carotid dysfunction in senescent female mice is mediated by increased α1A‐adrenoceptor activity and COX-derived vasoconstrictor prostanoids	22
Adverse pregnancy outcomes and renal-vascular function in the early years after delivery	21
Activation of IP3R in atrial cardiomyocytes leads to generation of cytosolic cAMP	21
Sex differences in cardiovascular disease and dysregulation in Down syndrome	21
Calcium handling dysfunction and cardiac damage following acute ventricular preload challenge in the dystrophin-deficient mouse heart	20
Cardiac myosin motor deficits are associated with left ventricular dysfunction in human ischemic heart failure	20
Race-specific changes in endothelial inflammation and microRNA in response to an acute inflammatory stimulus	20
Cardiac expression and location of hexokinase changes in a mouse model of pure creatine deficiency	20
Hypoxia-inducible factor-2α enhances neutrophil survival to promote cardiac injury following myocardial infarction	20
Serum dihydrotestosterone levels are associated with adverse myocardial remodeling in patients with severe aortic valve stenosis before and after aortic valve replacement	20
Modulation of p66Shc impairs cerebrovascular myogenic tone in low renin but not low nitric oxide models of systemic hypertension	20
CORP: Standardizing methodology for assessing spontaneous baroreflex control of muscle sympathetic nerve activity in humans	19
Deletion of the Aryl Hydrocarbon Receptor in Endothelial Cells Improves Ischemic Angiogenesis in Chronic Kidney Disease	19
The meaning of volume responsiveness and its relationship to venous return	19
Volume responsiveness revisited: an observational multicenter study of continuous versus binary outcomes combining echocardiography and venous return physiology	19

Habituation attenuates the sex-specific associations between ischemic pain, blood pressure, and arterial stiffness in young adults	19
Sildenafil administration improves right ventricular function on 4D flow MRI in young adults born premature	19
Reperfused vs. nonreperfused myocardial infarction: when to use which model	19
Anthracycline cardiotoxicity is exacerbated by global p38β genetic ablation in a sexually dimorphic manner but unaltered by cardiomyocyte-specific p38α loss	18
Hemodynamic simulation of complete transposition of the great arteries for optimal treatment strategies based on its circulatory physiology	18
Implications of Sm22α-Cre expression in keratinocytes and unanticipated inflammatory skin lesion in a model of atherosclerosis	18
An in silico approach to understanding the interaction between cardiovascular and pulmonary lymphatic dysfunction	18
Refining the reproducibility of a murine model of stress-induced reversible cardiomyopathy	18
A novel method for the percutaneous induction of myocardial infarction by occlusion of small coronary arteries in the rabbit	17
Inorganic nitrate supplementation attenuates conduit artery retrograde and oscillatory shear in older adults	17
Ensemble machine learning model identifies patients with HFpEF from matrix-related plasma biomarkers	17
The protective effect of remote ischemic conditioning is lost in patients with hypercholesterolemia	17
Blood pressure oscillations impact signal-averaged sympathetic transduction of blood pressure: implications for the association with resting sympathetic outflow	17
Impact of coronary hyperemia on collateral flow correction of coronary microvascular resistance indices	17
Cerebral arteriolar and neurovascular dysfunction after chemically induced menopause in mice	17
Impact of angiotensin II receptor antagonism on the sex-selective dysregulation of cardiovascular function induced by in utero dexamethasone exposure	17
Proteolytic degradation of atrial sarcomere proteins underlies contractile defects in atrial fibrillation	17
Female rats are less prone to clinical heart failure than male rats in a juvenile rat model of right ventricular pressure load	17
Mavacamten preserves length-dependent contractility and improves diastolic function in human engineered heart tissue	17
Lower estimates of myocardial perfusion are associated with greater aortic perivascular adipose tissue density in humans independent of aortic stiffness	17
Mechanisms of pulmonary vascular dysfunction in pulmonary hypertension and implications for novel therapies	16
Reply to Liu et al.	16
Loss of lung microvascular endothelial Piezo2 expression impairs NO synthesis, induces EndMT, and is associated with pulmonary hypertension	16
Endothelial-derived extracellular vesicles from obese/hypertensive adults increase factors associated with hypertrophy and fibrosis in cardiomyocytes	16
Sclerostin ablation prevents aortic valve stenosis in mice	16
Coronary vasodilation mediated by T cells expressing choline acetyltransferase	16
Angiotensin II type 1 receptor is involved in flow-induced vasomotor responses of isolated middle cerebral arteries: role of oxidative stress	16
Glial cell activity in cardiovascular diseases and risk of acute myocardial infarction	16
MicroRNA in pediatric pulmonary hypertension microRNA profiling to inform disease classification, severity, and treatment response in pediatric pulmonary hypertension	16
Extracellular Matrix Instability and Chronic Inflammation Underlie Maladaptive Right Ventricular Pressure Overload Remodeling and Failure in Male Mice	16
Importance of β2AR elevation for re-endothelialization capacity mediated by late endothelial progenitor cells in hypertensive patients	15
Mechanism and potential treatment of the “no reflow” phenomenon after acute myocardial infarction: role of pericytes and GPR39	15
Regulation of cerebrovascular compliance compared with forearm vascular compliance in humans: a pharmacological study	15
IL-33 supplementation improves uterine artery resistance and maternal hypertension in response to placental ischemia	15
Characterization of βARKct engineered cellular extracellular vesicles and model specific cardioprotection	15
Empagliflozin improves circulating vascular regenerative cell content in people without diabetes with risk factors for adverse cardiac remodeling	15
Impaired microvascular insulin-dependent dilation in women with a history of gestational diabetes	15
Calcium signaling in endothelial and vascular smooth muscle cells: sex differences and the influence of estrogens and androgens	15
An in silico study of the effects of cardiovascular aging on carotid flow waveforms and indexes in a virtual population	15
Long-term cardiovascular health status and physical functioning of nonhospitalized patients with COVID-19 compared with non-COVID-19 controls	15
Evaluation of early bilateral ovariectomy in mice as a model of left heart disease	15
Exercise in hypertrophic cardiomyopathy: restrict or rethink	15
Isoproterenol improves hemodynamics and right ventricle-pulmonary artery coupling after heart transplantation	15
Combination of reduced uterine perfusion pressure and leptin infusion as a novel model of preeclampsia	15
Altered calcium handling in cardiomyocytes from arginine-glycine amidinotransferase-knockout mice is rescued by creatine	15
USP20 deletion promotes eccentric cardiac remodeling in response to pressure overload and increases mortality	14
Biomarkers of intestinal permeability are associated with inflammation in metabolically healthy obesity but not normal-weight obesity	14
Elevated postischemic tissue injury and leukocyte-endothelial adhesive interactions in mice with global deficiency in caveolin-2: role of PAI-1	14
Electrical remodeling of atrioventricular junction: a study on retrogradely perfused chick embryonic heart	14
Carotid intima-media thickness and flow-mediated dilation do not predict acute in-hospital outcomes in patients hospitalized with COVID-19	14
Intracoronary ECG ST-segment shift remission time during reactive myocardial hyperemia: a new method to assess hemodynamic coronary stenosis severity	14
Taking to “heart” the proposed legislation for permanent daylight saving time	14
Gene expression networks in endothelial cells from failing human hearts	14
Mechanisms and clinical implications of endothelium-dependent vasomotor dysfunction in coronary microvasculature	14
FoxO4 controls sGCβ transcription in vascular smooth muscle	14
The importance of myosin ubiquitination status for cardiac remodeling: USP20 has entered the chat	14
Prenatal stress induces sex- and tissue-specific alterations in insulin pathway of Wistar rats offspring	14
Hypertension promotes microbial translocation and dysbiotic shifts in the fecal microbiome of nonhuman primates	14
Female sex-specific considerations to improve rigor and reproducibility in cardiovascular research	14
Deacetylation mimetic mutation of mitochondrial SOD2 attenuates ANG II-induced hypertension by protecting against oxidative stress and inflammation	14
New insights into mechanisms of endothelial insulin resistance in type 2 diabetes	13
Obesity blunts amelioration of cardiac hypertrophy and fibrosis by human mesenchymal stem/stromal cell-derived extracellular vesicles	13
Disturbed flow in the juxta-anastomotic area of an arteriovenous fistula correlates with endothelial loss, acute thrombus formation, and neointimal hyperplasia	13
New insight in understanding the contribution of SGLT1 in cardiac glucose uptake: evidence for a truncated form in mice and humans	13
Deficiency in nebulin repeats of sarcomeric nebulette is detrimental for cardiomyocyte tolerance to exercise and biomechanical stress	13
Cardiac PANK1 deletion exacerbates ventricular dysfunction during pressure overload	13
Augmented T-cell mitochondrial reactive oxygen species in adults with major depressive disorder	13
Guidelines for assessing ventricular pressure-volume relationships in rodents	13
Gender-affirming estrogen therapy route of administration and cardiovascular risk: a systematic review and narrative synthesis	13
Moderate aerobic exercise prevents matrix degradation and death in a mouse model of aortic dissection and aneurysm	13
Sex-dependent attenuating effects of capsaicin administration on the mechanoreflex in healthy rats	13
Enhanced endothelial barrier function by monoclonal antibody activation of vascular endothelial cadherin	13
Cardiac myosin binding protein-C phosphorylation accelerates β-cardiac myosin detachment rate in mouse myocardium	13
Sympathoexcitatory responses to renal chemosensitive stimuli are exaggerated at nighttime in rats	13
SGLT2 inhibition potentiates the cardiovascular, renal, and metabolic effects of sGC stimulation in hypertensive rats with prolonged exposure to high-fat diet	13
Nonmyocytes as electrophysiological contributors to cardiac excitation and conduction	13
Short-term salicylate treatment improves microvascular endothelium-dependent dilation in young adults with major depressive disorder	13
The multifaceted roles of red blood cells in health and disease	12
What frozen human hearts can tell us about treating heart failure	12
Placenta-targeted treatment with nMitoQ prevents an endothelin receptor-A pathway cardiac phenotype observed in adult male offspring exposed to hypoxia in utero	12

Myocardial injury, troponin release, and cardiomyocyte death in brief ischemia, failure, and ventricular remodeling	12
ATP induces contraction of cultured brain capillary pericytes via activation of P2Y-type purinergic receptors	12
Multidirectional blood flow in the femoral artery via vector flow imaging: Doppler ultrasound imaging insights	12
Sertraline-induced 5-HT dysregulation in mouse cardiomyocytes and the impact on calcium handling	12
Developmental nicotine exposure alters cardiovascular structure and function in neonatal and juvenile rats	12
Empagliflozin attenuates arrhythmogenesis in diabetic cardiomyopathy by normalizing intracellular Ca2+ handling in ventricular cardiomyocytes	12
Activation of the nonneuronal cholinergic cardiac system by hypoxic preconditioning protects isolated adult cardiomyocytes from hypoxia/reoxygenation injury	12
Diabetes mellitus disrupts lncRNA Malat1 regulation of cardiac mitochondrial genome-encoded protein expression	12
New cardiac targets for empagliflozin: O-GlcNAcylation, CaMKII, and calcium handling	12
Effect of Insulin on Indices of Cerebral Blood Flow and Cerebrovascular Compliance in Young Adults	12
Role of perivascular nerve and sensory neurotransmitter dysfunction in inflammatory bowel disease	12
Impact of exercise training on pulse wave velocity in healthy and clinical populations: a systematic review of systematic reviews	12
On the use and misuse of cerebral hemodynamics terminology using transcranial Doppler ultrasound: a call for standardization	12
Creating diversity, equity, inclusion, and accessibility statements for your CV: a resource guide to effectiveness and comprehensiveness	12
Fully automated mouse echocardiography analysis using deep convolutional neural networks	11
Sexual dimorphism of psychological stress-induced susceptibility to ischemic heart disease: Is the king naked?	11
Prenatal dexamethasone programs autonomic dysregulation in female rats	11
Statistical shape modeling reveals the link between right ventricular shape, hemodynamic force, and myocardial function in patients with repaired tetralogy of Fallot	11
Aortic distensibility is equal in prepubertal girls and boys and increases with puberty in girls	11
Acute partial sleep deprivation attenuates blood pressure responses to cycling exercise	11
The effects of chronic stress on rat heart function following regional ischemia: a sex-dependent investigation	11
Tissue inhibitor of metalloproteinase-4 deletion in mice impacts maternal cardiac function during pregnancy and postpartum	11
High variability in the reproducibility of key hemodynamic responses to head-up tilt	11
Differential effects of myosin activators on myocardial contractile function in nonfailing and failing human hearts	11
Vascular calcification: a left-handed compliment for aging	11
Reply to Cristóbal et al.	11
FBXL19 in endothelial cells protects the heart from influenza A infection by enhancing antiviral immunity and reducing cellular senescence programs	11
A cell atlas of thoracic aortic perivascular adipose tissue: a focus on mechanotransducers	11
Artificial intelligence for a personalized diagnosis and treatment of atrial fibrillation	11
Increased length-dependent activation of human engineered heart tissue after chronic α1A-adrenergic agonist treatment: testing a novel heart failure therapy	11
Constipation as a new nontraditional significant contributor to cardiovascular disease	11
Effect of cardiomyocyte-specific lipid phosphate phosphatase 3 overexpression on high-fat diet-induced cardiometabolic dysfunction in mice	11
Cardiovascular dysfunction induced by combined exposure to nicotine inhalation and high-fat diet	11
Reply to Madias	11
NLRP3 inflammasome-induced pyroptosis and serum ASC specks are increased in patients with cardiogenic shock	11
Mitochondrial contributions to vascular endothelial dysfunction, arterial stiffness, and cardiovascular diseases	11
Male and female high-fat diet-fed Dahl SS rats are largely protected from vascular dysfunctions: PVAT contributions reveal sex differences	11
Further refining of the murine model of intraperitoneal injection of isoproterenol-induced takotsubo syndrome	10
Reduced uterine perfusion pressure as a model for preeclampsia and fetal growth restriction in murine: a systematic review and meta-analysis	10
Intracellular and exosomal microRNAome profiling of human vascular smooth muscle cells during replicative senescence	10
A practical guide to graduate school interviewing for historically excluded individuals	10
Neuraminidase inhibition improves endothelial function in diabetic mice	10
Fine tuning contractility: atrial sarcomere function in health and disease	10
Is there an “athlete’s vein”?	10
Riding the wave: a quantitative report of electrocardiogram utilization for myocardial infarction confirmation	10
Supporting and promoting Black physiologists: how can the APS help?	10
Sigmoidal heart rate response pattern during exercise in patients with chronic heart failure	10
Reply to Boedtkjer and Aalkjaer	10
ETB receptor-mediated vasodilation is regulated by estradiol in young women	10
Seeking clarity on sex differences in cardiovascular complications of Down syndrome	10
Vascular complications from SARS-CoV2: a unique finding or a common feature of viral infections?	10
Differential negative effects of acute exhaustive swim exercise on the right ventricle are associated with disproportionate hemodynamic loading	10
Pygo1 regulates pathological cardiac hypertrophy via a β-catenin-dependent mechanism	10
Rapid vasodilation within contracted skeletal muscle in humans: new insight from concurrent use of diffuse correlation spectroscopy and Doppler ultrasound	10
Mutation of the 5′-untranslated region stem-loop mRNA structure reduces type I collagen deposition and arterial stiffness in male obese mice	10
Cardiac structures in marine animals provide insight on potential directions for interventions for pediatric congenital heart defects	10
S100A1’s single cysteine is an indispensable redox switch for the protection against diastolic calcium waves in cardiomyocytes	10
Global Genomic Profile of Hippocampal Endothelial cells by single nuclei RNA sequencing in Female Diabetic Mice is Associated with Cognitive Dysfunction	10
Realizing the price of academic freedom	9
Impact of ischemia on left atrial remodeling and dysfunction in swine models of mitral regurgitation	9
High-impact opportunities to address ischemia: a focus on heart and circulatory research	9
A guide to establishing, implementing, and optimizing diversity, equity, inclusion, and accessibility (DEIA) committees	9
Development and characterization of a mass cytometry panel for detecting the effect of acute doxorubicin exposure on murine cardiac nonmyocytes	9
Sleep disturbance and sympathetic neural reactivity in postmenopausal females	9
Unraveling the thread of uncontrolled immune response in COVID-19 and STEMI: an emerging need for knowledge sharing	9
Obesity-related vascular dysfunction persists after weight loss and is associated with decreased vascular glucagon-like peptide receptor in female rats	9
Noninvasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM	9
Impacts of circulating microRNAs in exercise-induced vascular remodeling	9
Lab-grown, 3D extracellular matrix particles improve cardiac function and morphology in myocardial ischemia	9
MEK1-ERK1/2 signaling regulates the cardiomyocyte non-sarcomeric actin cytoskeletal network	9
Implications for neutrophils in cardiac arrhythmias	9
Cardiac fibroblasts: answering the call	9
An antisense oligonucleotide efficiently suppresses splicing of an alternative exon in vascular smooth muscle in vivo	9
Mitochondrial respiration analysis in permeabilized porcine left ventricular and human right atrial specimens with ischemia-reperfusion	9
Interpretation of field and LEAP potentials recorded from cardiomyocyte monolayers	9
Capillary communication: the role of capillaries in sensing the tissue environment, coordinating the microvascular, and controlling blood flow	9
Electronic hookah (waterpipe) vaping reduces vascular endothelial function: the role of nicotine	9
Understanding changes in echocardiographic parameters at different ages following fetal growth restriction: a systematic review and meta-analysis	9
D-dimer in Marfan syndrome: effect of obstructive sleep apnea induced blood pressure surges	9
Stop the beat to see the rhythm: excitation-contraction uncoupling in cardiac research	9
Development of a Framework for the Hemodynamic Impact of Positive End-Expiratory Pressure in Normal and Heart Failure Conditions	9
Getting it right: preventing drift in baseline cardiovascular phenotype when using Sprague–Dawley rats	9
Arterial stiffness mediates the association between age and processing speed at low levels of microvascular function in humans across the adult lifespan	9
MicroRNAs regulating signaling pathways in cardiac fibrosis: potential role of the exercise training	9
Closing the window on COVID-19 case-control studies	9
(Re)modeling high-salt diet-induced hypertension in mice	9
Hemorheological, cardiorespiratory, and cerebrovascular effects of pentoxifylline following acclimatization to 3,800 m	9
Exercise-mitigated sex-based differences in aging: from genetic alterations to heart performance	9
A song of AAs and fire: divergent sex-dependent renal inflammatory mechanisms in hypertensive SLE mice	9
Aging models make waves: predicting vascular aging in virtual patients	9
Acellular human amniotic fluid protects the ischemic-reperfused rat myocardium	9
Selective elevation in external carotid artery flow during acute gravitational transition to microgravity during parabolic flight	9
Hemodynamic response of the aortic valve during dobutamine onset then progressive aortic banding	9
Overexpression of dimethylarginine dimethylaminohydrolase 1 protects from angiotensin II-induced cardiac hypertrophy and vascular remodeling	8
The influence of hemoconcentration on hypoxic pulmonary vasoconstriction in acute, prolonged, and lifelong hypoxemia	8