OOIR: Observatory of International Research

Papers

(The TQCC of American Journal of Physiology-Regulatory Integrative and Comparative is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
The glycocalyx: a central regulator of vascular function	67
Renal functional reserve: from physiological phenomenon to clinical biomarker and beyond	56
LPS versus Poly I:C model: comparison of long-term effects of bacterial and viral maternal immune activation on the offspring	46
Occupational heat exposure and the risk of chronic kidney disease of nontraditional origin in the United States	31
What is the physiological role of hypothalamic tanycytes in metabolism?	29
Developmental programming of peripheral diseases in offspring exposed to maternal obesity during pregnancy	28
ACE2: a key modulator of the renin-angiotensin system and pregnancy	24
High-altitude exposures and intestinal barrier dysfunction	24
Unique inflammatory profile is associated with higher SARS-CoV-2 acute respiratory distress syndrome (ARDS) mortality	23
Mineralocorticoid receptors in the pathogenesis of insulin resistance and related disorders: from basic studies to clinical disease	23
Objective pain stimulation intensity and pain sensation assessment using machine learning classification and regression based on electrodermal activity	23
Indole-3-propionic acid, a tryptophan-derived bacterial metabolite, increases blood pressure via cardiac and vascular mechanisms in rats	23
Early life stress in mice alters gut microbiota independent of maternal microbiota inheritance	23
Sepsis: network pathophysiology and implications for early diagnosis	22
NTS and VTA oxytocin reduces food motivation and food seeking	21
Sex differences in integrated neurocardiovascular control of blood pressure following acute intermittent hypercapnic hypoxia	20
Signal-averaged resting sympathetic transduction of blood pressure: is it time to account for prevailing muscle sympathetic burst frequency?	19
Parasympathetic activity is the key regulator of heart rate variability between decelerations during brief repeated umbilical cord occlusions in fetal sheep	19
Exercising muscle mass influences neuromuscular, cardiorespiratory, and perceptual responses during and following ramp-incremental cycling to task failure	19
Effects of regular sauna bathing in conjunction with exercise on cardiovascular function: a multi-arm, randomized controlled trial	18
Ventromedial hypothalamic nucleus glycogen regulation of metabolic-sensory neuron AMPK and neurotransmitter expression: role of lactate	18
Exogenous ketosis increases blood and muscle oxygenation but not performance during exercise in hypoxia	17
Flight training in a migratory bird drives metabolic gene expression in the flight muscle but not liver, and dietary fat quality influences select genes	17
Pre-locus coeruleus neurons in rat and mouse	16
The complex role of prostaglandin E₂-EP receptor signaling in wound healing	16

TRPV4 channel blockade does not modulate skin vasodilation and sweating during hyperthermia or cutaneous postocclusive reactive and thermal hyperemia	16
Sympathetic innervation of the mouse kidney and liver arising from prevertebral ganglia	16
Chronic hindbrain administration of oxytocin elicits weight loss in male diet-induced obese mice	15
Metabolism- and sex-dependent critical WBGT limits at rest and during exercise in the heat	15
Spectrum of myelinated pulmonary afferents (III): cracking intermediate adapting receptors	15
Progesterone-induced blocking factor improves blood pressure, inflammation, and pup weight in response to reduced uterine perfusion pressure (RUPP)	15
Effects of an acute exercise bout in hypoxia on extracellular vesicle release in healthy and prediabetic subjects	15
Lower citrate synthase activity, mitochondrial complex expression, and fewer oxidative myofibers characterize skeletal muscle from growth-restricted fetal sheep	15
Quantification of body fluid compartmentalization by combined time-domain nuclear magnetic resonance and bioimpedance spectroscopy	14
Lack of evidence for impaired preload or Bezold-Jarisch activation during brief umbilical cord occlusions in fetal sheep	14
Amylin antibodies frequently display cross-reactivity with CGRP: characterization of eight amylin antibodies	14
(Pro)renin receptor in the kidney: function and significance	14
Alamandine but not angiotensin-(1–7) produces cardiovascular effects at the rostral insular cortex	14
Proteomic analysis of mitochondrial biogenesis in cardiomyocytes differentiated from human induced pluripotent stem cells	14
Body mass-normalized moderate dose of dietary nitrate intake improves endothelial function and walking capacity in patients with peripheral artery disease	14
The role of astrocytes in the nucleus tractus solitarii in maintaining central control of autonomic function	14
The heat shock connection: skeletal muscle hypertrophy and atrophy	13
Hyperinsulinemia blunts sympathetic vasoconstriction: a possible role of β-adrenergic activation	13
Transcytosis within PVN capillaries: a mechanism determining both hypertension-induced blood-brain barrier dysfunction and exercise-induced correction	13
Activation of brain lactate receptor GPR81 aggravates exercise-induced central fatigue	13
Signaling in rat brainstem via Gpr160 is required for the anorexigenic and antidipsogenic actions of cocaine- and amphetamine-regulated transcript peptide	13
Impact of chorionic somatomammotropin RNA interference on uterine blood flow and placental glucose uptake in the absence of intrauterine growth restriction	13
High-fat feeding disrupts daily eating behavior rhythms in obesity-prone but not in obesity-resistant male inbred mouse strains	13
Hibernation is super complex: distribution, dynamics, and stability of electron transport system supercomplexes in Ictidomys tridecemlineatus	13
Effects of sex and menstrual cycle on volume-regulatory responses to 24-h fluid restriction	13
Insulin-like growth factor 1 signaling in the placenta requires endothelial nitric oxide synthase to support trophoblast function and normal fetal growth	13
Sympathetic transduction of blood pressure during graded lower body negative pressure in young healthy adults	12
Dynamic fluctuations in ascending heart-to-brain communication under mental stress	12
l-Citrulline supplementation during pregnancy improves perinatal and postpartum maternal vascular function in a mouse model of preeclampsia	12
Obese adipose tissue modulates proinflammatory responses of mouse airway epithelial cells	12
Role of angiotensin II in chronic intermittent hypoxia-induced hypertension and cognitive decline	12
How does density of the inner mitochondrial membrane influence mitochondrial performance?	12
Multiomic profiling of iron-deficient infant monkeys reveals alterations in neurologically important biochemicals in serum and cerebrospinal fluid before the onset of anemia	12
Metabolomic profiles are reflective of hypoxia-induced insulin resistance during exercise in healthy young adult males	12
Hydroxyurea improves nitric oxide bioavailability in humanized sickle cell mice	12
Activation of G protein-coupled estrogen receptor 1 ameliorates proximal tubular injury and proteinuria in Dahl salt-sensitive female rats	12
Increased vascular α1-adrenergic receptor sensitivity in older adults with posttraumatic stress disorder	11
Stimulation of soluble guanylate cyclase diminishes intrauterine growth restriction in a rat model of placental ischemia	11
Contribution of intracranial pressure to human dynamic cerebral autoregulation after acute brain injury	11
Menstrual phase and ambient temperature do not influence iron regulation in the acute exercise period	11
Determinants of cerebral blood flow velocity change during squat-stand maneuvers	11
Peripheral nerve adaptations to 10 days of horizontal bed rest in healthy young adult males	11
Skeletal muscle bioenergetic health and function in people living with HIV: association with glucose tolerance and alcohol use	11
Male bias in ACE2 basic science research: missed opportunity for discovery in the time of COVID-19	11
Chronic ablation of TRPV1-sensitive skeletal muscle afferents attenuates the muscle metaboreflex	11
Effects of exercise on thoracic blood volumes, lung fluid accumulation, and pulmonary diffusing capacity in heart failure with preserved ejection fraction	11
Neuromodulation or energy failure? Metabolic limitations silence network output in the hypoxic amphibian brainstem	10
Direct advice for directing an academic biomedical research laboratory	10
Fetal e-cigarette exposure programs a neonatal brain hypoxic-ischemic sensitive phenotype via altering DNA methylation patterns and autophagy signaling pathway	10
The 2021 Carl Ludwig Lecture. Unsympathetic autonomic regulation in heart failure: patient-inspired insights	10

Neural control of the spleen as an effector of immune responses to inflammation: mechanisms and treatments	10
Blunted sweating does not alter the rise in core temperature in people with multiple sclerosis exercising in the heat	10
V_1a and V_1b vasopressin receptors within the paraventricular nucleus contribute to hypertension in male rats exposed to chronic mild unpredictable stress	10
Inhibition of POMC neurons in mice undergoing activity-based anorexia selectively blunts food anticipatory activity without affecting body weight or food intake	10
Unilateral vagotomy alters astrocyte and microglial morphology in the nucleus tractus solitarii of the rat	10
Sugar-sweetened soft drink consumption acutely decreases spontaneous baroreflex sensitivity and heart rate variability	10
G protein-coupled lactate receptor GPR81 control of ventrolateral ventromedial hypothalamic nucleus glucoregulatory neurotransmitter and 5′-AMP-activated protein kinase expression	10
Talking the talk: tips for effective oral presentations in biomedical research	10
Migratory disposition alters lean mass dynamics and protein metabolism in migratory white-throated sparrows (Zonotrichia albicollis)	10
Body mass index, but not sex, influences exertional heat stroke risk in young healthy men and women	10
Global REACH 2018: volume regulation in high-altitude Andeans with and without chronic mountain sickness	10
Liver circadian clock disruption alters perivascular adipose tissue gene expression and aortic function in mice	9
Assessing functional sympatholysis during rhythmic handgrip exercise using Doppler ultrasound and near-infrared spectroscopy: sex differences and test-retest reliability	9
Aging reduces the maximal level of peripheral fatigue tolerable and impairs exercise capacity	9
Effects of chronic intermittent hypoxia on left cardiac function in young and aged mice	9
Interferon γ neutralization reduces blood pressure, uterine artery resistance index, and placental oxidative stress in placental ischemic rats	9
Publishing particulars: Part 1. The big picture	9
Pulsatile flow in venous perforators of the lower limb	9
Systematic review of the impact of genistein on diabetes-related outcomes	9
Pulmonary hypertension is attenuated and ventilation-perfusion matching is maintained during chronic hypoxia in deer mice native to high altitude	9
Acyloxyacyl hydrolase is a host determinant of gut microbiome-mediated pelvic pain	9
From skeletal muscle damage and regeneration to the hypertrophy induced by exercise: what is the role of different macrophage subsets?	9
Activation of the carotid body increases directly recorded cardiac sympathetic nerve activity and coronary blood flow in conscious sheep	9
Loss of hepatic PPARα in mice causes hypertension and cardiovascular disease	9
Effects of altitude and recombinant human erythropoietin on iron metabolism: a randomized controlled trial	9
Characterization of the circulating and tissue-specific alterations to the lipidome in response to moderate and major cold stress in mice	9
Time course of changes in V̇o_2peak and O₂ extraction during ramp cycle exercise following HIIT versus moderate-intensity continuous training in type 2 diabetes	8
Electrical pulse stimulation-induced muscle contraction alters the microRNA and mRNA profiles of circulating extracellular vesicles in mice	8
Effects of allergic airway inflammation and chronic intermittent hypoxia on systemic blood pressure	8
Publishing particulars: Part 3. General writing tips, editing, and responding to peer review	8
Seasonal changes of mitochondrial autophagy and oxidative response in the testis of the wild ground squirrels (Spermophilus dauricus)	8
Revisiting the question of nucleated versus enucleated erythrocytes in birds and mammals	8
Targeting the Toll-like receptor pathway as a therapeutic strategy for neonatal infection	8
The protective role of SOD1 overexpression in central mediation of bradycardia following chronic intermittent hypoxia in mice	8
Low-dose fentanyl reduces pain perception, muscle sympathetic nerve activity responses, and blood pressure responses during the cold pressor test	8
Use of a carbonic anhydrase Ca17a knockout to investigate mechanisms of ion uptake in zebrafish (Danio rerio)	8
Rapid and persistent decrease in brain tissue oxygenation in ovine gram-negative sepsis	8
Cardiometabolic effects of DOCA-salt in male C57BL/6J mice are variably dependent on sodium and nonsodium components of diet	8
Relationships between reproductive hormones and maternal pregnancy physiology in women conceiving with or without in vitro fertilization	8
Orexin facilitates the ventilatory and behavioral responses of rats to hypoxia	8
Autophagic response to exercise in peripheral blood mononuclear cells from young men is intensity-dependent and is altered by exposure to environmental heat	8
A comparison of medium-term heat acclimation by post-exercise hot water immersion or exercise in the heat: adaptations, overreaching, and thyroid hormones	8
Hypertension is associated with blunted NO-mediated leg vasodilator responsiveness that is reversed by high-intensity training in postmenopausal women	8
Impact of acute antioxidant supplementation on vascular function and autonomic nervous system modulation in young adults with PTSD	8
Aldehyde dehydrogenase 2 deficiency promotes skeletal muscle atrophy in aged mice	8
Endothelial HSP72 is not reduced in type 2 diabetes nor is it a key determinant of endothelial insulin sensitivity	8
Chemogenetic activation of noradrenergic A5 neurons increases blood pressure and visceral sympathetic activity in adult rats	8
Chronic binge alcohol and ovariectomy-mediated impaired insulin responsiveness in SIV-infected female rhesus macaques	8
Revisiting the evaluation of central versus peripheral thermoregulatory control in humans	8
Fetal growth, high altitude, and evolutionary adaptation: a new perspective	8
Nesfatin-1 stimulates the hypothalamus-pituitary-interrenal axis hormones in goldfish	8
Changes of the cardiac baroreflex bandwidth during postural challenges	8
Chronic hypoxia alters cardiac mitochondrial complex protein expression and activity in fetal guinea pigs in a sex-selective manner	8
Effect of endoplasmic reticulum stress on endothelial ischemia-reperfusion injury in humans	7
Cyclooxygenase-2 deficiency attenuates lipopolysaccharide-induced inflammation, apoptosis, and acute lung injury in adult mice	7
Maternal vitamin B₁₂ in mice positively regulates bone, but not muscle mass and strength in post-weaning and mature offspring	7
High-fat/high-sucrose diet worsens metabolic outcomes and widespread hypersensitivity following early-life stress exposure in female mice	7
Thermogenic responses to different clamped skin temperatures in cold-exposed men and women	7
Astrocytic responses to high glucose impair barrier formation in cerebral microvessel endothelial cells	7
The involvement of renal afferents in the maintenance of cardiorenal diseases	7
From inhibition of trophoblast cell invasion to proapoptosis: what are the potential roles of kisspeptins in preeclampsia?	7
Elephant seal muscle cells adapt to sustained glucocorticoid exposure by shifting their metabolic phenotype	7
Skeletal muscle blood flow during exercise is reduced in a rat model of pulmonary hypertension	7
Species-specific metabolic responses of songbird, shorebird, and murine cultured myotubes to n-3 polyunsaturated fatty acids	7
Anemic hypoxemia reduces myoblast proliferation and muscle growth in late-gestation fetal sheep	7
Hypoxic preconditioning reduces endothelial ischemia-reperfusion injury in older adults	7
Nerve transfer for restoration of lower motor neuron-lesioned bladder function. Part 1: attenuation of purinergic bladder smooth muscle contractions	7
Publishing particulars: Part 2. Tips for effective manuscript development	7
Effects of air pollution exposure on inflammatory and endurance performance in recreationally trained cyclists adapted to traffic-related air pollution	7
Renal and hypothalamic inflammation in renovascular hypertension: role of afferent renal nerves	7
HIF-1 regulates energy metabolism of the Tibetan chicken brain during embryo development under hypoxia	7
Individual arcuate nucleus proopiomelanocortin neurons project to select target sites	7
Impact of sex and diet-induced weight loss on vascular insulin sensitivity in type 2 diabetes	7
Epithelial sodium channels in macrophage migration and polarization: role of proinflammatory cytokines TNFα and IFNγ	7
Lipid oxidation during thermogenesis in high-altitude deer mice (Peromyscus maniculatus)	7
Targeting mineralocorticoid receptors in diet-induced hepatic steatosis and insulin resistance	7
Independent and interactive effects of thermal stress and mental fatigue on manual dexterity	7