OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Labelled Compounds & Radiopharmaceuticals is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Use of radioiodine in nuclear medicine—A brief overview	23
Radiosynthesis and quality control testing of the tau imaging positron emission tomography tracer [¹⁸F]PM‐PBB3 for clinical applications	16
Radioiodination of balsalazide, bioevaluation, and characterization as a highly selective radiotracer for imaging of ulcerative colitis in mice	13
Production of [⁸⁹Zr]Oxinate₄ and cell radiolabeling for human use	12
Automated radiosynthesis of [⁶⁸Ga]Ga‐PSMA‐11 and [¹⁷⁷Lu]Lu‐PSMA‐617 on the iPHASE MultiSyn module for clinical applications	11
Strategies for designing novel positron emission tomography (PET) radiotracers to cross the blood–brain barrier	8
Fully automated production of the fibroblast activation protein radiotracer [¹⁸F]FAPI‐74	8
Review: Self‐radiolysis of compounds containing tritium and carbon‐14	7
Polyethylene oxide–polyacrylic acid–folic acid (PEO‐PAAc) nanogel as a^99mTc targeting receptor for cancer diagnostic imaging	7
Copper‐mediated radioiodination reaction through aryl boronic acid or ester precursor and its application to direct radiolabeling of a cyclic peptide	7
Peptides for trans‐blood–brain barrier delivery	6
A practical approach to the optimization of positron emission tomography imaging agents for the central nervous system	6
Development of an automated production process of [⁶⁴Cu][Cu (ATSM)] for positron emission tomography imaging and theranostic applications	6
Preclinical evaluation of anti‐VEGFR2 monoclonal antibody ramucirumab labelled with zirconium‐89 for tumour imaging	5
Evaluating N‐difluoromethyltriazolium triflate as a precursor for the synthesis of high molar activity [¹⁸F]fluoroform	5
Carbon‐11 carboxylation of terminal alkynes with [¹¹C]CO₂	4
Synthesis and automated fluorine‐18 radiolabeling of new PSMA‐617 derivatives with a CuAAC radiosynthetic approach	4
Synthesis of [H‐3]‐ and [C‐14]‐labeled elagolix	4
Synthesis of deuterium‐labeled cinnamic acids: Understanding the volatile benzenoid pathway in the flowers of the Japanese loquat Eriobotrya japonica	4
Preparation, Characterization, and Radiolabeling of Anti‐HER2 scFv With Technetium Tricarbonyl and Stability Studies	4
Detailed radiosynthesis of [¹⁸F]mG4P027 as a positron emission tomography radiotracer for mGluR4	4
The impact of radiochemistry in drug projects: The use of C‐14 label in the AZD8529, AZD7325, and AZD6280 projects	4
Synthesis and analysis of isotopically stable labeled nitrosamines as mass spectrometry standards for drug impurity quality control	3
A practical and environmentally friendly protocol for synthesis of α‐deuterated carboxylic acids	3
Exploration of alcohol‐enhanced Cu‐mediated radiofluorination toward practical labeling	3

Carbon 14 synthesis of glycine transporter 1 inhibitor Iclepertin (BI 425809) and its major metabolites	3
Comparison of three different methods in [⁶⁸Ga]Ga‐PSMA11 radiolabeling	3
Isotopically labelled compounds in research projects of life sciences	3
Highly selective catalytic transfer hydrodeuteration of cyclic alkenes	3
Luminescence enhancement by deuterium	3
The inverse electron demand Diels–Alder cycloaddition with carbon‐11 and fluorine‐18: A gateway to pretargeted imaging across the blood–brain barrier	3
Synthesis of [¹³C₆]‐ibrutinib	3
An improved one‐pot preparation of [¹⁸F]FMISO based on solid phase extraction purification: Pitfalls on the analytical method reported in the Ph.Eur.'s monograph	3
Automated radiosynthesis of 1‐(2‐[¹⁸F]fluoroethyl)‐L‐tryptophan ([¹⁸F]FETrp) for positron emission tomography (PET) imaging of cancer in humans	3
Development of a novel [¹⁸F]fluorobenzyl derivative of the AT₁ receptor antagonist Candesartan	3
Synthesis of ¹³C‐labelled cutin and suberin monomeric dicarboxylic acids of the general formula HO₂¹³C‐(CH₂)_n‐¹³CO₂H (n<	3
An optimized radiosynthesis of [¹⁸F]DK222, a PET radiotracer for imaging PD‐L1	2
Radiosynthesis of ³H‐ and ¹⁴C‐labeled Veliparib	2
Good manufacturing procedure production of [¹⁸F]SynVesT‐1, a radioligand for in vivo positron emission tomography imaging of synaptic vesicle glycoprotein 2A	2
Novel developed HPLC analyses of [⁶⁸Ga]Ga/[¹⁷⁷Lu]Lu‐EDTMP and [⁶⁸Ga]Ga/[¹⁷⁷Lu]Lu‐DOTA‐Zoledronate	2
An efficient and general method for the synthesis of stable isotope deuterium labeled phthalate esters	2
Process validation, current good manufacturing practice production, dosimetry, and toxicity studies of the carbonic anhydrase IX imaging agent [¹¹¹In]In‐XYIMSR‐01 for phase I regulatory app	2
Development of a ⁶⁸Ga‐labelled PET tracer for carbonic anhydrase IX‐overexpressed tumors using the artificial sweetener saccharin	2
Benzylic deuteration of alkylnitroaromatics via amine‐base catalysed exchange with deuterium oxide	2
Enzymatic synthesis of halogen derivatives of L‐phenylalanine and phenylpyruvic acid stereoselectively labeled with hydrogen isotopes in the side chain	2
High‐yield synthesis of a tau PET radioligand and its nonradioactive ligand using an alternative protection and deprotection strategy	2
Automated synthesis of (R)‐[¹⁸F]MH.MZ on the iPhase Flexlab reaction platform	2
Automated radiosynthesis of the adenosine A_2A receptor‐targeting radiotracer [¹⁸F]FLUDA	2
Development of radiotracers for riboflavin transporter 3 imaging in diseases—A brief overview	2
Improved protocol for the radiosynthesis of [¹⁸F]FTC‐146: A potent and selective sigma‐1 receptor radioligand	2
Synthesis of [²H₅]baricitinib via [²H₅]ethanesulfonyl chloride	2
Preparation, quality control, and biodistribution assessment of [¹¹¹In]In‐DOTA‐PR81 in BALB/c mice bearing breast tumors	2
An updated synthesis of N₁′‐([¹¹C]methyl)naltrindole for positron emission tomography imaging of the delta opioid receptor	2
Development and physicochemical characterization of a biodegradable microspheres formulation loaded with samarium‐153 and doxorubicin for chemo‐radioembolization of liver tumours	2
Fluorine‐18 labeled aldehydes as prosthetic groups for oxime coupling with a FVIIa protein	2
Copper‐mediated nucleophilic radiofluorination of [¹⁸F]β‐CFT for positron emission tomography imaging of dopamine transporter	2
Automated radiosynthesis of [¹¹C]MTP38—a phosphodiesterase 7 imaging tracer—using [¹¹C]hydrogen cyanide for clinical applications	2
Synthesis of a dual carbon‐14‐labeled calcitonin gene‐related peptide receptor antagonist for use in a human absorption–distribution–metabolism–elimination study	2
Mild and selective hydrogen–deuterium exchange for aromatic hydrogen of amines	1
[¹⁸F]Fluoropyridine‐losartan: A new approach toward human Positron Emission Tomography imaging of Angiotensin II Type 1 receptors	1
Issue Information	1
Research on preparation and in vitro evaluation of the dendrimer–peptide nuclear acid conjugate for amplification pretargeting	1
Tritium hydrogen‐isotope exchange with electron‐poor tertiary benzenesulfonamide moiety; application in late‐stage labeling of T0901317	1
Determination of isotope abundance for deuterium‐labeled compounds by quantitative ¹H NMR + ²H NMR	1
An Improved HPLC Separation Method for TSPO Radioligand [¹¹C]ER176 Clinical Production	1
Simplified and accessible [¹⁸F]F‐AraG synthesis procedure for preclinical PET	1
Fully Automated Cassette‐Based Synthesis of 2‐Deoxy‐2‐[¹⁸F]Fluorocellobiose Using Trasis AllInOne Module	1
In vivo and in vitro binding of [¹²⁵I]I‐R‐(+)‐TISCH: A dopamine D₁ receptor ligand for studying pancreatic β‐cell mass	1
Synthesis of ¹³C‐labeled parabens from isotopically enriched phenols using the Houben–Hoesch reaction	1
A facile synthesis of isotope labeled acylcarnitines	1
An improved synthesis of [¹⁸F]VAT and its precursor	1
Preparation and biological evaluation of radioiodine‐labeled triphenylphosphine derivatives as mitochondrial targeting probes	1
Total synthesis of [¹³C₂]‐labeled phytosiderophores of the mugineic and avenic acid families	1
Highly effective liquid and solid phase extraction methods to concentrate radioiodine isotopes for radioiodination chemistry	1
Radiosynthesis and validation of [¹⁸F]fluoroestradiol in a Synthra plus research platform for use in routine clinical practice	1

Synthesis of beta‐site amyloid precursor protein‐cleaving enzyme 1 inhibitors BI 1147560 and BI 1181181 labeled with carbon‐14 and deuterium	1
Exploring the enzyme‐catalyzed synthesis of isotope labeled cyclopropanes	1
The impact of zirconium‐89 solution formulation on the efficiency of [⁸⁹Zr]Zr‐deferoxamine synthesis	1
Synthesis and radiolabeling of a polar [¹²⁵I]I‐1,2,4,5‐tetrazine	1
Automated radiochemical synthesis of pharmaceutical grade [¹⁸F]FLT using 3‐N‐Boc‐5′‐O‐dimethoxytrityl‐3′‐O‐nosyl‐thymidine precursor and its Sep‐Pak® purification employing selective elutio	1
RO6807936 as a novel positron emission tomography (PET) radiotracer for in vitro and in vivo visualization and quantification of beta‐site amyloid precursor protein cleaving enzyme (BACE1) in the rode	1
The synthesis of deuteriated tri‐tert‐butyl phosphine	1
Low‐scale syringe‐made synthesis of ¹⁵N‐labeled oligonucleotides	1
Efficient synthesis of carbon‐14 labeled metabolites of the strobilurin fungicide mandestrobin using biomimetic iron‐porphyrin catalyzed oxidation	1
A comparative study on Suzuki‐type ¹¹C‐methylation of aromatic organoboranes performed in two reaction media	1
Synthesis of [4S‐²H]NADH, [4R‐²H]NADH, [4‐²H₂]NADH and [4‐²H]NAD⁺ cofactors through heterogeneous biocatalysis in heavy	1
Preliminary PET imaging of [¹¹C]evobrutinib in mouse models of colorectal cancer, SARS‐CoV‐2, and lung damage: Radiosynthesis via base‐aided palladium‐NiXantphos‐mediated ¹¹C‐car	1
Ultra‐fast liquid chromatography method coupled with ultraviolet detection to quantify dimethylsulfoxide, dimethylformamide and dimethylacetamide in short half‐lives radiopharmaceuticals	1
Synthesis of tritium labeled 30‐KDa PEG and conjugation to form [³H]Pegbelfermin	1
Site‐specifically radiolabeled nanobodies for imaging blood‐brain barrier penetration and targeting in the brain	1
Small‐scale two‐dimensional liquid chromatography for a preparative re‐purification of a highly labile tritium‐labeled compound	1