OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Labelled Compounds & Radiopharmaceuticals is 0. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Radiosynthesis and validation of [¹⁸F]fluoroestradiol in a Synthra plus research platform for use in routine clinical practice	13
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A synthesis of [¹⁴C]formamidine acetate	7
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Formulation of patient dose of [¹⁷⁷Lu]Lu‐Trastuzumab using in‐house developed freeze‐dried kit: A path forward for clinical translation	6
Meet our Special Issue Editor: Jessica Bridoux	6
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Meet our advisors: Mathew Thakur	5
Determination of isotope abundance for deuterium‐labeled compounds by quantitative ¹H NMR + ²H NMR	4
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Preparation of [1′‐¹³C]citric acid as a probe in a breath test to evaluate tricarboxylic acid cycle flux	4
Practical approaches to labelling terminal alkynes with deuterium	4
Automated radiolabeling and handling of ¹⁷⁷Lu‐ and ²²⁵Ac‐PSMA‐617 using a robotic pipettor	4
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Meet our advisors: Bart Cornelissen	3
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Comparison of three different methods in [⁶⁸Ga]Ga‐PSMA11 radiolabeling	3
Preclinical evaluation of anti‐VEGFR2 monoclonal antibody ramucirumab labelled with zirconium‐89 for tumour imaging	3
Highly effective liquid and solid phase extraction methods to concentrate radioiodine isotopes for radioiodination chemistry	3
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A comparative study on Suzuki‐type ¹¹C‐methylation of aromatic organoboranes performed in two reaction media	3
Meet our advisors: Crist N. Filer	3
Meet our advisors: Neil Vasdev	3
Efficient Reductive N‐¹¹C‐Methylation Using Arylamines or Alkylamines and In Situ–Generated [¹¹C]Formaldehyde From [¹¹C]Methyl Iodide	2
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Radiosynthesis of ³H‐ and ¹⁴C‐labeled Veliparib	2
Synthesis and preclinical evaluation of a selective MET kinase positron emission tomography tracer	2
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Abstracts From the 29th International Isotope Society UK Meeting 17th November 2023	2
Total synthesis of [¹³C₂]‐labeled phytosiderophores of the mugineic and avenic acid families	2
Direct Multi‐Deuterium Labelling of Pirtobrutinib	2
Tritium hydrogen‐isotope exchange with electron‐poor tertiary benzenesulfonamide moiety; application in late‐stage labeling of T0901317	2
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Strategies for designing novel positron emission tomography (PET) radiotracers to cross the blood–brain barrier	2
Meet our advisors: Jordi Llop	2
Efficient synthesis of carbon‐14 labeled metabolites of the strobilurin fungicide mandestrobin using biomimetic iron‐porphyrin catalyzed oxidation	2
A flow electrochemistry‐enabled synthesis of 2‐substituted N‐(methyl‐d)piperidines	2
¹⁴C‐radiolabeling of a new steroidal antiandrogen with a C‐18 angular methyl extension	1
Applications of radiolabeled antibodies in neuroscience and neuro‐oncology	1
Synthesis of trifold‐labeled versatile reagent [3,5‐¹³C₂,4‐¹⁵ N]4‐phenyl‐1,2,4‐triazoline‐3,5‐dione	1
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Synthesis of ¹³C‐labelled ω‐hydroxy carboxylic acids of the general formula HO₂¹³C‐(CH₂)_n‐CH₂OH or HO₂C‐(CH₂	1
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Meet our advisors—Matteo Zanda	1
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Enzymatic synthesis of halogen derivatives of L‐phenylalanine and phenylpyruvic acid stereoselectively labeled with hydrogen isotopes in the side chain	1
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Synthesis of N‐acetyl‐l‐aspartyl‐l‐glutamic acid; [³H]NAAG	1
Synthesis of BI 894416 and BI 1342561, two potent and selective spleen tyrosine kinase inhibitors, labeled with carbon 14 and with deuterium	1
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Synthesis of deuterium‐labeled CCR2 antagonist JNJ‐26131300, [4‐(1H‐indol‐ 3‐yl)‐piperidin‐1‐yl]‐{1‐[3‐(3,4,5‐trifluoro‐phenyl)‐acryloyl]‐piperidin‐4‐yl}‐acetic acid	1
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Radioiodination of balsalazide, bioevaluation, and characterization as a highly selective radiotracer for imaging of ulcerative colitis in mice	1
Research on preparation and in vitro evaluation of the dendrimer–peptide nuclear acid conjugate for amplification pretargeting	1
Development of a high‐performance liquid chromatography method for rapid radiochemical purity measurement of [¹⁸F]PSMA‐1007, a PET radiopharmaceutical for detection of prostate cancer	1
Preparation and biological evaluation of radioiodine‐labeled triphenylphosphine derivatives as mitochondrial targeting probes	1
Low‐scale syringe‐made synthesis of ¹⁵N‐labeled oligonucleotides	1
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Development of ¹¹C‐labeled CRANAD‐102 for positron emission tomography imaging of soluble Aβ‐species	1
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Highly selective catalytic transfer hydrodeuteration of cyclic alkenes	0
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Review: Self‐radiolysis of compounds containing tritium and carbon‐14	0
A Brief Review of Radiolabelling Nucleic Acid‐Based Molecules for Tracking and Monitoring	0
Development of an automated production process of [⁶⁴Cu][Cu (ATSM)] for positron emission tomography imaging and theranostic applications	0
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A facile synthesis of precursor for the σ‐1 receptor PET radioligand [¹⁸F]FTC‐146 and its radiofluorination	0
Synthesis and evaluation of ¹¹¹In‐labeled tetrapeptide‐based compounds as single‐photon emission computed tomography imaging probes targeting granzyme B	0
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Site‐specifically radiolabeled nanobodies for imaging blood‐brain barrier penetration and targeting in the brain	0
Meet the editors: Danielle Vugts	0
RO6807936 as a novel positron emission tomography (PET) radiotracer for in vitro and in vivo visualization and quantification of beta‐site amyloid precursor protein cleaving enzyme (BACE1) in the rode	0
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Fully Automated Cassette‐Based Synthesis of 2‐Deoxy‐2‐[¹⁸F]Fluorocellobiose Using Trasis AllInOne Module	0
Meet our advisors: An interview with John Katzenellenbogen	0
Preparation, Characterization, and Radiolabeling of Anti‐HER2 scFv With Technetium Tricarbonyl and Stability Studies	0
Tritium and deuterium labelling of a kainate receptor antagonist and evaluation as a radioligand	0
[¹⁸F]‐labeled positron emission tomography ligand for the histamine H4 receptor	0
Improving Routine ⁸⁹Zr‐Immuno‐PET Applications: Mild Iron Removal Can Favor the Use of Fe‐DFO‐N‐suc‐TFP Ester Over p‐NCS‐Bz‐DFO	0
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Automated radiosynthesis of [¹⁸F]CETO, a PET radiotracer for imaging adrenal glands, on Synthra RNplus	0
¹¹C‐Carbonylation for PET Imaging and Drug Discovery	0
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Synthesis and Preclinical Evaluation of [¹⁸F]AlF‐NOTA‐Asp₂‐PEG₂‐Folate as a Novel Folate‐Receptor‐Targeted Tracer for PET Imaging	0
Synthesis of Deuterated Endochin‐Like Quinolones	0
Synthesis of [H‐3]‐ and [C‐14]‐labeled elagolix	0
Carbon 14 synthesis of glycine transporter 1 inhibitor Iclepertin (BI 425809) and its major metabolites	0
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Automated radiosynthesis of the adenosine A_2A receptor‐targeting radiotracer [¹⁸F]FLUDA	0
A practical and environmentally friendly protocol for synthesis of α‐deuterated carboxylic acids	0
Lead‐212/Bismuth‐212 In Vivo Generator Based on Ultrasmall Silver Telluride Nanoparticles	0
Next Generation of Solid Target Radionuclide Antibody Conjugates for Tumor Immuno‐Therapy	0
Synthesis of [³H]Org24598 using in‐house prepared [³H]MeI	0
Synthesis and analysis of isotopically stable labeled nitrosamines as mass spectrometry standards for drug impurity quality control	0
Validation of a good manufacturing practice procedure for the production of [¹¹C]AZD4747, a CNS penetrant KRAS^G12c inhibitor	0
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Development of an economical method to synthesize O‐(2‐[¹⁸F]fluoroethyl)‐L‐tyrosine (¹⁸FFET)	0
Stable isotope synthesis of glycine transporter 1 inhibitor Iclepertin (BI 425809) and its major metabolites	0
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Novel developed HPLC analyses of [⁶⁸Ga]Ga/[¹⁷⁷Lu]Lu‐EDTMP and [⁶⁸Ga]Ga/[¹⁷⁷Lu]Lu‐DOTA‐Zoledronate	0
Synthesis and radiolabeling of a polar [¹²⁵I]I‐1,2,4,5‐tetrazine	0
Meet the advisors ‐ Suzy Lapi	0
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Simplified Flow Photosynthesis of Deuterium‐Labeled Pyocyanin	0
Synthesis of [²H₅]baricitinib via [²H₅]ethanesulfonyl chloride	0
¹⁸F‐Fluorination of a supported 2‐(aryl‐di‐tert‐butylsilyl)‐N‐methyl‐imidazole for indirect ¹⁸F‐labeling of a V_HH single‐variable domain	0
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Synthesis and spectroscopic characterization of ¹³C₄‐labeled 4‐cyano‐2‐oxobutyraldehyde semicarbazone: A metabolite of nitrofurazone	0
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Polyethylene oxide–polyacrylic acid–folic acid (PEO‐PAAc) nanogel as a^99mTc targeting receptor for cancer diagnostic imaging	0
High‐yielding, automated radiosynthesis of [¹¹C]martinostat using [¹¹C]methyl triflate	0
Copper‐mediated radioiodination reaction through aryl boronic acid or ester precursor and its application to direct radiolabeling of a cyclic peptide	0
Synthesis of Stable Isotope, Tritiated, and Carbon‐14 Labeled Balcinrenone	0
Simplified and accessible [¹⁸F]F‐AraG synthesis procedure for preclinical PET	0
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Exploration of alcohol‐enhanced Cu‐mediated radiofluorination toward practical labeling	0
Automated radiochemical synthesis of pharmaceutical grade [¹⁸F]FLT using 3‐N‐Boc‐5′‐O‐dimethoxytrityl‐3′‐O‐nosyl‐thymidine precursor and its Sep‐Pak® purification employing selective elutio	0
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[11C]CO2 BOP fixation with amines to access 11C‐labeled ureas for PET imaging	0
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Synthesis of [¹³C₆]‐ibrutinib	0
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Carbon‐11 carboxylation of terminal alkynes with [¹¹C]CO₂	0
A practical approach to the optimization of positron emission tomography imaging agents for the central nervous system	0
Radiolabeling and brain penetration of [¹¹C]VU0071063, a ligand of type 1 sulfonylurea receptors for positron emission tomography imaging	0
[¹⁸F]Fluoropyridine‐losartan: A new approach toward human Positron Emission Tomography imaging of Angiotensin II Type 1 receptors	0
Application of Microfluidic Devices for Automated Two‐Step Radiolabeling of Antibodies	0
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Carbon‐14 Labeling Synthesis of RORγt Inhibitor JNJ‐61803534	0
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An improved synthesis of [¹⁸F]VAT and its precursor	0
Automated radiosynthesis of mGluR5 PET tracer [¹⁸F]FPEB from aryl‐chloro precursor and validation for clinical application	0
Obituary	0
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Novel synthesis of ¹¹C‐labeled imidazolines via Pd(0)‐mediated ¹¹C‐carbomethoxylation using [¹¹C]CO and arylborons	0
Mild and selective hydrogen–deuterium exchange for aromatic hydrogen of amines	0
Synthesis of Radiolabeled [¹⁴C]Rimsulfuron and Stable Isotope Labeled Rimsulfuron‐[M + 3] to Support Crop Metabolism Studies for Reregistration	0
Copper‐mediated nucleophilic radiofluorination of [¹⁸F]β‐CFT for positron emission tomography imaging of dopamine transporter	0
Synthesis and Evaluation of a Cathepsin B–Recognizing Trifunctional Chelating Agent to Improve Tumor Retention of Radioimmunoconjugates	0
The synthesis of deuteriated tri‐tert‐butyl phosphine	0
[⁶⁸Ga]Ga‐PentixaFor: Development of a fully automated in hospital production on the Trasis miniAllinOne synthesizer	0
A practical approach to the optimization of positron emission tomography imaging agents for the central nervous system	0
Synthesis of tritium labeled 30‐KDa PEG and conjugation to form [³H]Pegbelfermin	0
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Synthesis and Application of D‐ and ¹³C‐Labelled tert‐Butyl Hoechst Dye	0
Detailed radiosynthesis of [¹⁸F]mG4P027 as a positron emission tomography radiotracer for mGluR4	0
Carbon 14 and Carbon 13 Syntheses of Velagliflozin	0
Blood Brain Barrier – tactics and attributes in developing successful neuroimaging agents	0
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Exploring the enzyme‐catalyzed synthesis of isotope labeled cyclopropanes	0
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Synthesis and automated fluorine‐18 radiolabeling of new PSMA‐617 derivatives with a CuAAC radiosynthetic approach	0
An efficient and general method for the synthesis of stable isotope deuterium labeled phthalate esters	0
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Good manufacturing procedure production of [¹⁸F]SynVesT‐1, a radioligand for in vivo positron emission tomography imaging of synaptic vesicle glycoprotein 2A	0
Small‐scale two‐dimensional liquid chromatography for a preparative re‐purification of a highly labile tritium‐labeled compound	0
Preparation and evaluation of radiolabeled acetaminosalol microspheres: A new potential selective radiotracer for ulcerative colitis early diagnosis	0
Facile synthesis of ¹⁴C‐nitrofurazone from ¹⁴C‐urea	0
Evaluating N‐difluoromethyltriazolium triflate as a precursor for the synthesis of high molar activity [¹⁸F]fluoroform	0
Luminescence enhancement by deuterium	0
Ultra‐fast liquid chromatography method coupled with ultraviolet detection to quantify dimethylsulfoxide, dimethylformamide and dimethylacetamide in short half‐lives radiopharmaceuticals	0
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Initial evaluation of ^99mTc‐labeled anti‐carcinoembryonic antigen single‐chain fragment variable for micro‐single‐photon emission computed tomography imaging in mice with colorectal cancer	0
Synthesis of ¹³C‐labeled parabens from isotopically enriched phenols using the Houben–Hoesch reaction	0
Nitrilase mediated mild hydrolysis of a carbon‐14 nitrile for the radiosynthesis of 4‐(7‐hydroxycarbamoyl‐[1‐¹⁴C‐heptanoyl]‐oxy)‐benzoic acid methyl ester, [¹⁴C]‐SHP‐141: A novel	0
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A practical protocol for large‐scale copper‐mediated radioiodination of organoboronic precursors: Radiosynthesis of [¹²³I]KX‐1 for Auger radiotherapy	0
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Development of radiotracers for riboflavin transporter 3 imaging in diseases—A brief overview	0
Automated radiosynthesis of 1‐(2‐[¹⁸F]fluoroethyl)‐L‐tryptophan ([¹⁸F]FETrp) for positron emission tomography (PET) imaging of cancer in humans	0
Meet our advisors: Billy Kerr	0
An improved radiosynthesis of [¹⁸F]FAraG, a PET radiotracer for imaging T‐cell activation	0
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Meet the advisors: An interview with Gunnar Antoni	0
In vivo and in vitro binding of [¹²⁵I]I‐R‐(+)‐TISCH: A dopamine D₁ receptor ligand for studying pancreatic β‐cell mass	0
Meet the editorial staff—Interview series	0
Peptides for trans‐blood–brain barrier delivery	0
Fully automated production of the fibroblast activation protein radiotracer [¹⁸F]FAPI‐74	0
Synthesis of a dual carbon‐14‐labeled calcitonin gene‐related peptide receptor antagonist for use in a human absorption–distribution–metabolism–elimination study	0
An Improved HPLC Separation Method for TSPO Radioligand [¹¹C]ER176 Clinical Production	0
Improved protocol for the radiosynthesis of [¹⁸F]FTC‐146: A potent and selective sigma‐1 receptor radioligand	0
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Benzylic deuteration of alkylnitroaromatics via amine‐base catalysed exchange with deuterium oxide	0
Automated production of ¹¹C‐labeled carboxylic acids and esters via “in‐loop” ¹¹C‐carbonylation using GE FX synthesis modules	0
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Development and physicochemical characterization of a biodegradable microspheres formulation loaded with samarium‐153 and doxorubicin for chemo‐radioembolization of liver tumours	0
Synthesis of beta‐site amyloid precursor protein‐cleaving enzyme 1 inhibitors BI 1147560 and BI 1181181 labeled with carbon‐14 and deuterium	0
Meet our advisors: Dieter Muri	0
Preliminary Research of Radiolabeled Atezolizumab for the Noninvasive Evaluation of TNBC PD‐L1 Expression In Vivo	0
An optimized radiosynthesis of [¹⁸F]DK222, a PET radiotracer for imaging PD‐L1	0
Preliminary PET imaging of [¹¹C]evobrutinib in mouse models of colorectal cancer, SARS‐CoV‐2, and lung damage: Radiosynthesis via base‐aided palladium‐NiXantphos‐mediated ¹¹C‐car	0
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Open‐source flow setup for rapid and efficient [¹⁸F]fluoride drying for automation of PET tracer syntheses	0
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Radioiodination, purification, and evaluation of antihuman tumor‐derived immunoglobulin G light chain monoclonal antibody in tumor‐bearing nude mice	0
The inverse electron demand Diels–Alder cycloaddition with carbon‐11 and fluorine‐18: A gateway to pretargeted imaging across the blood–brain barrier	0
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An improved one‐pot preparation of [¹⁸F]FMISO based on solid phase extraction purification: Pitfalls on the analytical method reported in the Ph.Eur.'s monograph	0
Carbon 14 and stable isotope synthesis of two potent and selective phosphodiesterase type 4 inhibitors	0
Photocatalyzed radiosynthesis of ¹¹C‐phenylacetic acids	0
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⁶⁸Ga Radiolabeling of NODASA‐Functionalized Phage Display–Derived Peptides for Prospective Assessment as Tuberculosis‐Specific PET Radiotracers	0
Wiley Young Scientist Awards were handed over at the 14th International Symposium on the synthesis on the Synthesis and Applications of Isotopically Labelled Compounds in Raleigh, USA	0
Towards Optimal Automated ⁶⁸Ga‐Radiolabeling Conditions of the DOTA‐Bisphosphonate BPAMD Without Pre‐Purification of the Generator Eluate	0
A facile synthesis of isotope labeled acylcarnitines	0
A simplified protocol for the automated production of 2‐[¹⁸F]fluoro‐3‐[2‐((S)‐3‐pyrrolinyl)methoxy]pyridine ([¹⁸F]nifene) on an IBA Synthera® module	0
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Automated synthesis of (R)‐[¹⁸F]MH.MZ on the iPhase Flexlab reaction platform	0
Synthesis of deuterium‐labeled cinnamic acids: Understanding the volatile benzenoid pathway in the flowers of the Japanese loquat Eriobotrya japonica	0
Meet our advisors: Bill Lockley	0
Evaluation and improvement of CuI‐mediated ¹¹C‐cyanation	0
Synthesis of carbon‐14 and stable isotope labeled Censavudine	0