OOIR: Observatory of International Research

Papers

(The TQCC of Annual Review of Pharmacology and Toxicology is 34. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-09-01 to 2024-09-01.)

Article	Citations
Nanoparticle Toxicology	192
Arsenic: A Global Environmental Challenge	170
Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span	167
Preventing and Treating Anthracycline Cardiotoxicity: New Insights	95
Targeting NRF2 and Its Downstream Processes: Opportunities and Challenges	88
Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy	84
E-Cigarette Toxicology	79
Thioredoxin Reductase Inhibition for Cancer Therapy	78
A New Old Target: Androgen Receptor Signaling and Advanced Prostate Cancer	67
Antisense Drugs Make Sense for Neurological Diseases	60
TRP Channel Cooperation for Nociception: Therapeutic Opportunities	60
Clinical Pharmacology and Interplay of Immune Checkpoint Agents: A Yin-Yang Balance	55
Targeting Endocannabinoid Signaling: FAAH and MAG Lipase Inhibitors	55
Aryl Hydrocarbon Receptor and Its Diverse Ligands and Functions: An Exposome Receptor	47
Brain-Protective Mechanisms of Transcription Factor NRF2: Toward a Common Strategy for Neurodegenerative Diseases	46
Neuropathic Pain: Mechanisms, Sex Differences, and Potential Therapies for a Global Problem	46
Endocrine-Disrupting Chemicals and Child Health	45
Immune Checkpoint Inhibitor Cardiotoxicity: Understanding Basic Mechanisms and Clinical Characteristics and Finding a Cure	44
Oxidative Stress and Metabolism: A Mechanistic Insight for Glyphosate Toxicology	43
Noncanonical Metabotropic Glutamate Receptor 5 Signaling in Alzheimer's Disease	42
Endocannabinoid-Based Therapies	41
New Drugs, Old Targets: Tweaking the Dopamine System to Treat Psychostimulant Use Disorders	41
Oral Biologic Delivery: Advances Toward Oral Subunit, DNA, and mRNA Vaccines and the Potential for Mass Vaccination During Pandemics	39
Drugs That Regulate Local Cell Signaling: AKAP Targeting as a Therapeutic Option	39
The CXCL12/CXCR4/ACKR3 Axis in the Tumor Microenvironment: Signaling, Crosstalk, and Therapeutic Targeting	38

CaMKII as a Therapeutic Target in Cardiovascular Disease	37
Structural Basis of SARS-CoV-2– and SARS-CoV–Receptor Binding and Small-Molecule Blockers as Potential Therapeutics	36
Store-Operated Ca²⁺ Channels: Mechanism, Function, Pharmacology, and Therapeutic Targets	36
Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond	36
G Protein–Coupled Estrogen Receptor GPER: Molecular Pharmacology and Therapeutic Applications	35
Development of New Tuberculosis Drugs: Translation to Regimen Composition for Drug-Sensitive and Multidrug-Resistant Tuberculosis	35
Drug Target Identification in Tissues by Thermal Proteome Profiling	34
The Gut Microbiome, Metformin, and Aging	34
Artificial Intelligence for Drug Discovery: Are We There Yet?	34
Pharmacologic Approach to Sinoatrial Node Dysfunction	34