Annual Review of Pharmacology and Toxicology

(The TQCC of Annual Review of Pharmacology and Toxicology is 25. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
Nanoparticle Toxicology163
Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span148
Arsenic: A Global Environmental Challenge129
Targeting NRF2 and Its Downstream Processes: Opportunities and Challenges76
Preventing and Treating Anthracycline Cardiotoxicity: New Insights75
Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy72
Thioredoxin Reductase Inhibition for Cancer Therapy64
E-Cigarette Toxicology55
A New Old Target: Androgen Receptor Signaling and Advanced Prostate Cancer55
TRP Channel Cooperation for Nociception: Therapeutic Opportunities53
Antisense Drugs Make Sense for Neurological Diseases51
Clinical Pharmacology and Interplay of Immune Checkpoint Agents: A Yin-Yang Balance51
Targeting Endocannabinoid Signaling: FAAH and MAG Lipase Inhibitors50
Immune Checkpoint Inhibitor Cardiotoxicity: Understanding Basic Mechanisms and Clinical Characteristics and Finding a Cure40
Oral Biologic Delivery: Advances Toward Oral Subunit, DNA, and mRNA Vaccines and the Potential for Mass Vaccination During Pandemics38
New Drugs, Old Targets: Tweaking the Dopamine System to Treat Psychostimulant Use Disorders37
Aryl Hydrocarbon Receptor and Its Diverse Ligands and Functions: An Exposome Receptor37
Drugs That Regulate Local Cell Signaling: AKAP Targeting as a Therapeutic Option37
Endocrine-Disrupting Chemicals and Child Health36
Noncanonical Metabotropic Glutamate Receptor 5 Signaling in Alzheimer's Disease35
Brain-Protective Mechanisms of Transcription Factor NRF2: Toward a Common Strategy for Neurodegenerative Diseases34
Structural Basis of SARS-CoV-2– and SARS-CoV–Receptor Binding and Small-Molecule Blockers as Potential Therapeutics33
Oxidative Stress and Metabolism: A Mechanistic Insight for Glyphosate Toxicology33
Endocannabinoid-Based Therapies33
Store-Operated Ca2+ Channels: Mechanism, Function, Pharmacology, and Therapeutic Targets32
Mechanism of Action of TiO2: Recommendations to Reduce Uncertainties Related to Carcinogenic Potential30
Pharmacologic Approach to Sinoatrial Node Dysfunction30
Development of New Tuberculosis Drugs: Translation to Regimen Composition for Drug-Sensitive and Multidrug-Resistant Tuberculosis29
Drug Target Identification in Tissues by Thermal Proteome Profiling29
Neuropathic Pain: Mechanisms, Sex Differences, and Potential Therapies for a Global Problem28
The CXCL12/CXCR4/ACKR3 Axis in the Tumor Microenvironment: Signaling, Crosstalk, and Therapeutic Targeting27
Two-Pore Domain Potassium Channels as Drug Targets: Anesthesia and Beyond27
The Gut Microbiome, Metformin, and Aging25
Use of DREADD Technology to Identify Novel Targets for Antidiabetic Drugs25
Challenges and Opportunities in Implementing Pharmacogenetic Testing in Clinical Settings25