Brain Research Bulletin

Article	Citations
Brain–gut–microbiota axis in depression: A historical overview and future directions	110
Melatonin improves hypoxic-ischemic brain damage through the Akt/Nrf2/Gpx4 signaling pathway	81
Adolescent drug exposure: A review of evidence for the development of persistent changes in brain function	75
Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules	70
Analysis of knowledge bases and research focuses of cerebral ischemia-reperfusion from the perspective of mapping knowledge domain	70
Hypothermia protects neurons against ischemia/reperfusion-induced pyroptosis via m6A-mediated activation of PTEN and the PI3K/Akt/GSK-3β signaling pathway	69
Mental Health Issues During and After COVID-19 Vaccine Era	60
Case-fatality, disability and recurrence rates after first-ever stroke: A study from bigdata observatory platform for stroke of China	59
Brain-spleen axis in health and diseases: A review and future perspective	46
LncRNA BDNF-AS promotes autophagy and apoptosis in MPTP-induced Parkinson’s disease via ablating microRNA-125b-5p	45
Mesenchymal stem cells-derived mitochondria transplantation mitigates I/R-induced injury, abolishes I/R-induced apoptosis, and restores motor function in acute ischemia stroke rat model	44
Epilepsy and Alzheimer’s Disease: Potential mechanisms for an association	44
cGAS knockdown promotes microglial M2 polarization to alleviate neuroinflammation by inhibiting cGAS-STING signaling pathway in cerebral ischemic stroke	43
Gut microbiome improves postoperative cognitive function by decreasing permeability of the blood-brain barrier in aged mice	42
Naringenin improves depressive- and anxiety-like behaviors in mice exposed to repeated hypoxic stress through modulation of oxido-inflammatory mediators and NF-kB/BDNF expressions	42
The interplay between sleep and gut microbiota	42
Bone marrow mesenchymal stem cell-derived exosomal microRNA-125a promotes M2 macrophage polarization in spinal cord injury by downregulating IRF5	41
Butyrate alleviates PTZ-induced mitochondrial dysfunction, oxidative stress and neuron apoptosis in mice via Keap1/Nrf2/HO-1 pathway	40
Curcumin alleviates neuroinflammation, enhances hippocampal neurogenesis, and improves spatial memory after traumatic brain injury	40
Effects of vanillic acid on Aβ1-40-induced oxidative stress and learning and memory deficit in male rats	40
Astrocyte-derived exosome-transported microRNA-34c is neuroprotective against cerebral ischemia/reperfusion injury via TLR7 and the NF-κB/MAPK pathways	37
An Overview on the Mechanisms of Neuroprotection and Neurotoxicity of Isoflurane and Sevoflurane in Experimental Studies	37
RNA demethylase Alkbh5 is widely expressed in neurons and decreased during brain development	36
Proteolytic cleavage of proBDNF to mBDNF in neuropsychiatric and neurodegenerative diseases	36
Concomitant enlargement of perivascular spaces and decrease in glymphatic transport in an animal model of cerebral small vessel disease	35

Ferroptosis and traumatic brain injury	34
IN VITRO AND IN VIVO MODELS OF AMYOTROPHIC LATERAL SCLEROSIS: AN UPDATED OVERVIEW	34
Echinacoside protects dopaminergic neurons by inhibiting NLRP3/Caspase-1/IL-1β signaling pathway in MPTP-induced Parkinson’s disease model	33
Selenium inhibits ferroptosis and ameliorates autistic-like behaviors of BTBR mice by regulating the Nrf2/GPx4 pathway	33
Impairment of learning and memory induced by perinatal exposure to BPA is associated with ERα-mediated alterations of synaptic plasticity and PKC/ERK/CREB signaling pathway in offspring rats	32
Geniposide protects depression through BTK/JAK2/STAT1 signaling pathway in lipopolysaccharide-induced depressive mice	32
Anti-inflammatory and immunomodulatory effects of baicalin in cerebrovascular and neurological disorders	32
Melatonin ameliorates anxiety-like behaviors induced by sleep deprivation in mice: Role of oxidative stress, neuroinflammation, autophagy and apoptosis	31
Sodium orthovanadate improves learning and memory in intracerebroventricular-streptozotocin rat model of Alzheimer’s disease through modulation of brain insulin resistance induced tau pathology	31
Hydrogen sulfide antagonizes sleep deprivation-induced depression- and anxiety-like behaviors by inhibiting neuroinflammation in a hippocampal Sirt1-dependent manner	29
Exosomal microRNA-23b-3p from bone marrow mesenchymal stem cells maintains T helper/Treg balance by downregulating the PI3k/Akt/NF-κB signaling pathway in intracranial aneurysm	28
Multiple inflammatory profiles of microglia and altered neuroimages in APP/PS1 transgenic AD mice	28
Gut microbiota modulates stress-induced hypertension through the HPA axis	27
Modulation of nose-to-brain delivery of a P-glycoprotein (MDR1) substrate model drug (quinidine) in rats	26
Plasma levels of ceramides relate to ischemic stroke risk and clinical severity	26
IGF-1R stimulation alters microglial polarization via TLR4/NF-κB pathway after cerebral hemorrhage in mice	26
Metformin attenuates sevoflurane-induced neurocognitive impairment through AMPK-ULK1-dependent autophagy in aged mice	26
Ganoderma lucidum polysaccharides ameliorated depression-like behaviors in the chronic social defeat stress depression model via modulation of Dectin-1 and the innate immune system	26
Repeated exposure to propofol in the neonatal period impairs hippocampal synaptic plasticity and the recognition function of rats in adulthood	26
Treadmill exercise ameliorates chronic REM sleep deprivation-induced anxiety-like behavior and cognitive impairment in C57BL/6J mice	25
Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: The role of medial prefrontal cortex 5-HT1A and CB1 rec	25
Unraveling correlative roles of dopamine transporter (DAT) and Parkin in Parkinson’s disease (PD) – A road to discovery?	25
lncRNA Mtss1 promotes inflammatory responses and secondary brain injury after intracerebral hemorrhage by targeting miR-709 in mice	25
Oral treatment with glycyrrhizin inhibits NLRP3 inflammasome activation and promotes microglial M2 polarization after traumatic spinal cord injury	24
Antidepressant effect of catalpol on corticosterone-induced depressive-like behavior involves the inhibition of HPA axis hyperactivity, central inflammation and oxidative damage probably via dual regu	24
Targeting pyroptosis to regulate ischemic stroke injury: Molecular mechanisms and preclinical evidences	24
Sericin protects against acute sleep deprivation-induced memory impairment via enhancement of hippocampal synaptic protein levels and inhibition of oxidative stress and neuroinflammation in mice	23
Downregulation of lncRNA KCNQ1OT1 relieves traumatic brain injury induced neurological deficits via promoting "M2" microglia polarization	23
Up-regulated microRNA-218-5p ameliorates the damage of dopaminergic neurons in rats with Parkinson’s disease via suppression of LASP1	23
Berberine exerts neuroprotective activities against cerebral ischemia/reperfusion injury through up-regulating PPAR-γ to suppress NF-κB-mediated pyroptosis	23
Electroacupuncture pretreatment prevents ischemic stroke and inhibits Wnt signaling-mediated autophagy through the regulation of GSK-3β phosphorylation	22
The central role of tau in Alzheimer’s disease: From neurofibrillary tangle maturation to the induction of cell death	22
BMSCs-exosomes containing GDF-15 alleviated SH-SY5Y cell injury model of Alzheimer's disease via AKT/GSK-3β/β-catenin	22
Treadmill exercise mitigates neuroinflammation and increases BDNF via activation of SIRT1 signaling in a mouse model of T2DM	22
Electroacupuncture alleviated the depression-like behavior by regulating FGF2 and astrocytes in the hippocampus of rats with chronic unpredictable mild stress	22
Mirror therapy in upper limb motor recovery and activities of daily living, and its neural correlates in stroke individuals: A systematic review and meta-analysis	22
hUC-MSCs ameliorated CUMS-induced depression by modulating complement C3 signaling-mediated microglial polarization during astrocyte-microglia crosstalk	22
Promotion of Momordica Charantia polysaccharides on neural stem cell proliferation by increasing SIRT1 activity after cerebral ischemia/reperfusion in rats	21
Saikosaponin d downregulates microRNA-155 and upregulates FGF2 to improve depression-like behaviors in rats induced by unpredictable chronic mild stress by negatively regulating NF-κB	21
Complexities and paradoxes in understanding the role of dopamine in incentive motivation and instrumental action: Exertion of effort vs. anhedonia	21
Effects of sub-concussion on neuropsychological performance and its potential mechanisms: A narrative review	21
RETRACTED: Bone marrow mesenchymal stem cells-derived extracellular vesicles carrying microRNA-221-3p protect against ischemic stroke via ATF3	21
Agmatine improves the behavioral and cognitive impairments associated with chronic gestational ethanol exposure in rats	21
Effect of Wnt signaling pathway on neurogenesis after cerebral ischemia and its therapeutic potential	20
The significance of sialylation on the pathogenesis of Alzheimer’s disease	20
Microarray assay of circular RNAs reveals cicRNA.7079 as a new anti-apoptotic molecule in spinal cord injury in mice	20
Sodium aescinate provides neuroprotection in experimental traumatic brain injury via the Nrf2-ARE pathway	20
Post-stroke depression: Chaos to exposition	20
Repetitive transcranial magnetic stimulation in traumatic brain injury: Evidence from animal and human studies	20
Neuroprotective effects of leptin on cerebral ischemia through JAK2/STAT3/PGC-1-mediated mitochondrial function modulation	20

Cerebral ischemia-reperfusion aggravated cerebral infarction injury and possible differential genes identified by RNA-Seq in rats	19
TRPA1 involvement in depression- and anxiety-like behaviors in a progressive multiple sclerosis model in mice	19
Corilagin ameliorates sleep deprivation-induced memory impairments by inhibiting NOX2 and activating Nrf2	19
N2L, a novel lipoic acid-niacin dimer, attenuates ferroptosis and decreases lipid peroxidation in HT22 cells	19
Molecular targets and therapeutic interventions for iron induced neurodegeneration	19
Inhibition of ERK1/2 phosphorylation attenuates spinal cord injury induced astrocyte activation and inflammation through negatively regulating aquaporin-4 in rats	19
The barrier and interface mechanisms of the brain barrier, and brain drug delivery	19
ECM hydrogel improves the delivery of PEG microsphere-encapsulated neural stem cells and endothelial cells into tissue cavities caused by stroke	19
Involvement of endoplasmic reticulum stress in amyloid β (1-42)-induced Alzheimer’s like neuropathological process in rat brain	19
Rapid acting antidepressants in the mTOR pathway: Current evidence	19
The effects of glucagon-like peptide 1 receptor agonist (exenatide) on memory impairment, and anxiety- and depression-like behavior induced by REM sleep deprivation	18
Effects of acute versus recurrent insulin-induced hypoglycemia on ventromedial hypothalamic nucleus metabolic-sensory neuron AMPK activity: Impact of alpha1-adrenergic receptor signaling	18
Regulation of SPARC family proteins in disorders of the central nervous system	18
Esketamine alleviates postoperative cognitive decline via stimulator of interferon genes/ TANK‐binding kinase 1 signaling pathway in aged rats	18
Lin28a attenuates cerebral ischemia/reperfusion injury through regulating Sirt3-induced autophagy	18
Role of the locus coeruleus and basal forebrain in arousal and attention	18
NOD2 regulates microglial inflammation through the TAK1-NF-κB pathway and autophagy activation in murine pneumococcal meningitis	18
A literature overview on epilepsy and inflammasome activation	18
Long-lasting effects of postweaning sodium butyrate exposure on social behaviors in adult mice	18
SNHG16 aggravates chronic constriction injury-induced neuropathic pain in rats via binding with miR-124-3p and miR-141-3p to upregulate JAG1	18
Age-dependent Alteration in Mitochondrial Dynamics and Autophagy in Hippocampal Neuron of Cannabinoid CB1 Receptor-deficient Mice	18
MicroRNAs expressed in neuronal differentiation and their associated pathways: Systematic review and bioinformatics analysis	18
Chronic hyperglycemia induces tau hyperphosphorylation by downregulating OGT-involved O-GlcNAcylation in vivo and in vitro	18
Constraint-induced movement therapy improves functional recovery after ischemic stroke and its impacts on synaptic plasticity in sensorimotor cortex and hippocampus	18
Morin exerts protective effects on encephalopathy and sepsis-associated cognitive functions in a murine sepsis model	17
Therapeutic potential of catalpol and geniposide in Alzheimer’s and Parkinson’s diseases: A snapshot of their underlying mechanisms	17
Time-dependent effects of platelet-rich plasma on the memory and hippocampal synaptic plasticity impairment in vascular dementia induced by chronic cerebral hypoperfusion	17
Ketamine reversed short-term memory impairment and depressive-like behavior in animal model of Parkinson's disease	17
Ruthenium red, mitochondrial calcium uniporter inhibitor, attenuates cognitive deficits in STZ-ICV challenged experimental animals	17
Validation of reference genes for gene expression analysis following experimental traumatic brain injury in a pediatric mouse model	17
Salidroside shows anticonvulsant and neuroprotective effects by activating the Nrf2-ARE pathway in a pentylenetetrazol-kindling epileptic model	17
Mechanistic evaluation of Ursolic acid against rotenone induced Parkinson’s disease– emphasizing the role of mitochondrial biogenesis	17
Epimedium flavonoids protect neurons and synapses in the brain via activating NRG1/ErbB4 and BDNF/Fyn signaling pathways in a chronic cerebral hypoperfusion rat model	17
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway	17
Maternal separation plus social isolation during adolescence reprogram brain dopamine and endocannabinoid systems and facilitate alcohol intake in rats	17
NLRP3 inflammasome inhibition by histone acetylation ameliorates sevoflurane-induced cognitive impairment in aged mice by activating the autophagy pathway	17
Brain-gut-microbiota axis in Parkinson’s disease: A historical review and future perspective	17
GYY4137 protects against MCAO via p38 MAPK mediated anti-apoptotic signaling pathways in rats	16
Sleep-wake and arousal dysfunctions in post-traumatic stress disorder: Role of orexin systems	16
Effect of electroacupuncture on the expression of P2 × 4, GABAA γ 2 and long-term potentiation in spinal cord of rats with neuropathic pain	16
A novel model of blast induced traumatic brain injury caused by compressed gas produced sustained cognitive deficits in rats: involvement of phosphorylation of tau at the Thr205 epitope	16
Antioxidant and anti-apoptotic effects of cannabidiol in model of ischemic stroke in rats	16
Adult conditional knockout of PGC-1α in GABAergic neurons causes exaggerated startle reactivity, impaired short-term habituation and hyperactivity	16
Potassium channels and their emerging role in parkinson's disease	16
Comprehensive circular RNA profiling reveals that hsa_circ_0001368 is involved in growth hormone-secreting pituitary adenoma development	15
FTY720 in CNS injuries: Molecular mechanisms and therapeutic potential	15
Sex-related patterns of the gut-microbiota-brain axis in the neuropsychiatric conditions	15
Antibiotic-induced gut microbiota depletion from early adolescence exacerbates spatial but not recognition memory impairment in adult male C57BL/6 mice with Alzheimer-like disease	15
Prevention and reversal of ketamine-induced experimental psychosis in mice by the neuroactive flavonoid, hesperidin: The role of oxidative and cholinergic mechanisms	15
Neuroprotective effects of microRNA-140-5p on ischemic stroke in mice via regulation of the TLR4/NF-κB axis	15
WBSCR22 confers cell survival and predicts poor prognosis in glioma	15
Downregulation of LncRNA Gas5 inhibits apoptosis and inflammation after spinal cord ischemia-reperfusion in rats	15
Chronic unpredictable stress negatively regulates hippocampal neurogenesis and promote anxious depression-like behavior via upregulating apoptosis and inflammatory signals in adult rats	15
Cerebral cavernous malformation 3 relieves subarachnoid hemorrhage-induced neuroinflammation in rats through inhibiting NF-kB signaling pathway	15
Preventive putative mechanisms involved in the psychopathologies of mice passively coping with psychosocial defeat stress by quercetin	15
The abnormal firing of Purkinje cells in the knockin mouse model of DYT1 dystonia	15
Silencing lncRNA HOTAIR improves the recovery of neurological function in ischemic stroke via the miR-148a-3p/KLF6 axis	15
Neuroprotective role of alendronate against APP processing and neuroinflammation in mice fed a high fat diet	15
The effects of astaxanthin treatment on a rat model of Alzheimer’s disease	15
The neuroprotective effect of MicroRNA-149-5p and coenzymeQ10 by reducing levels of inflammatory cytokines and metalloproteinases following focal brain ischemia in rats	14
Angiopoietin-like 4 promotes angiogenesis and neurogenesis in a mouse model of acute ischemic stroke	14
The selenocompound 1-methyl-3-(phenylselanyl)-1H-indole attenuates depression-like behavior, oxidative stress, and neuroinflammation in streptozotocin-treated mice	14
Nuclear receptor TLX may be through regulating the SIRT1/NF-κB pathway to ameliorate cognitive impairment in chronic cerebral hypoperfusion	14
Research on developing drugs for Parkinson's disease	14
Regulation of neurotoxicity in the striatum and colon of MPTP-induced Parkinson’s disease mice by gut microbiome	14
Voluntary wheel-running exercise attenuates brain aging of rats through activating miR-130a-mediated autophagy	14
The role of nicotinic acetylcholine receptors in alcohol-related behaviors	14
Protective effects of fraxin on cerebral ischemia-reperfusion injury by mediating neuroinflammation and oxidative stress through PPAR-γ/NF-κB pathway	14
Chronic NaHS treatment improves spatial and passive avoidance learning and memory and anxiety-like behavior and decreases oxidative stress in rats fed with a high-fat diet	14
Overexpression of HDAC6, but not HDAC3 and HDAC4 in the penumbra after photothrombotic stroke in the rat cerebral cortex and the neuroprotective effects of α-phenyl tropolone, HPOB, and sodium valproa	14
CB1-cannabinoid-, TRPV1-vanilloid- and NMDA-glutamatergic-receptor-signalling systems interact in the prelimbic cerebral cortex to control neuropathic pain symptoms	14
Nicotinamide mononucleotide administration after sever hypoglycemia improves neuronal survival and cognitive function in rats	14
Pubertal probiotics mitigate lipopolysaccharide-induced programming of the hypothalamic-pituitary-adrenal axis in male mice only	14
miR-18b attenuates cerebral ischemia/reperfusion injury through regulation of ANXA3 and PI3K/Akt signaling pathway	14
An early increase in glutamate is critical for the development of depression-like behavior in a chronic restraint stress (CRS) model	14
XQ-1H regulates Wnt/GSK3β/β-catenin pathway and ameliorates the integrity of blood brain barrier in mice with acute ischemic stroke	14
BDNF promotes neuronal survival after neonatal hypoxic-ischemic encephalopathy by up-regulating Stx1b and suppressing VDAC1	13
MiR-410-3p overexpression ameliorates neurological deficits in rats with hypoxic-ischemic brain damage	13
The L1 cell adhesion molecule affects protein kinase D1 activity in the cerebral cortex in a mouse model of Alzheimer’s disease	13
Magnesium-L-threonate alleviate colonic inflammation and memory impairment in chronic-plus-binge alcohol feeding mice	13

Intramuscular insulin-like growth factor-1 gene therapy modulates reactive microglia after traumatic brain injury	13
Restoring lost nigrostriatal fibers in Parkinson’s disease based on clinically-inspired design criteria	13
Tanshinone IIA suppresses lipopolysaccharide-induced neuroinflammatory responses through NF-κB/MAPKs signaling pathways in human U87 astrocytoma cells	13
Down-regulated long non-coding RNA RMST ameliorates dopaminergic neuron damage in Parkinson’s disease rats via regulation of TLR/NF-κB signaling pathway	13
MiR-26b-5p-modified hUB-MSCs derived exosomes attenuate early brain injury during subarachnoid hemorrhage via MAT2A-mediated the p38 MAPK/STAT3 signaling pathway	13
Role of calcium/calmodulin-dependent kinase 2 in neurodevelopmental disorders	13
Guanosine protects against behavioural and mitochondrial bioenergetic alterations after mild traumatic brain injury	13
Commensal microbe-derived propionic acid mediates juvenile social isolation-induced social deficits and anxiety-like behaviors	13
Characterization of transection spinal cord injuries by monitoring somatosensory evoked potentials and motor behavior	13
Potential neurotoxic activity of diverse molecules released by astrocytes	13
Iron toxicity in intracerebral hemorrhage: Physiopathological and therapeutic implications	13
Bidirectional communication between mast cells and the gut-brain axis in neurodegenerative diseases: Avenues for therapeutic intervention	13
Formalin-induced inflammatory pain increases excitability in locus coeruleus neurons	12
Electromagnetic field protects against cognitive and synaptic plasticity impairment induced by electrical kindling in rats	12
Safinamide in neurological disorders and beyond: Evidence from preclinical and clinical studies	12
The neuroprotective effects of Insulin-Like Growth Factor 1 via the Hippo/YAP signaling pathway are mediated by the PI3K/AKT cascade following cerebral ischemia/reperfusion injury	12
The role of endocannabinoid pathway in the neuropathology of Alzheimer’s disease: Can the inhibitors of MAGL and FAAH prove to be potential therapeutic targets against the cognitive impairment associa	12
Alterations in the behavior, cognitive function, and BDNF level in adult male rats following neonatal blockade of GABA-A receptors	12
Aerobic exercise training decreases cognitive impairment caused by demyelination by regulating ROCK signaling pathway in aging mice	12
Hydrogen-saturated saline mediated neuroprotection through autophagy via PI3K/AKT/mTOR pathway in early and medium stages of rotenone-induced Parkinson’s disease rats	12
Minocycline inhibits sleep deprivation-induced aberrant microglial activation and Keap1-Nrf2 expression in mouse hippocampus	12
Multiple roles of fucoxanthin and astaxanthin against Alzheimer's disease: Their pharmacological potential and therapeutic insights	12
MicroRNA-455–5p/CPEB1 pathway mediates Aβ-related learning and memory deficits in a mouse model of Alzheimer’s disease	12
Dynamic changes of activated AHR in microglia and astrocytes in the substantia nigra-striatum system in an MPTP-induced Parkinson’s disease mouse model	12
The role of REST/NRSF, TrkB and BDNF in neurobiological mechanisms of different susceptibility to seizure in a PTZ model of epilepsy	12
STAT4 and COL1A2 are potential diagnostic biomarkers and therapeutic targets for heart failure comorbided with depression	12
De novo proteomic methods for examining the molecular mechanisms underpinning long-term memory	12
Antidepressant-like effects of acupuncture via modulation of corticosterone, sex hormones, and hippocampal BDNF expression in male rats	12
Immunomodulation by dimethyl fumarate treatment improves mouse sciatic nerve regeneration	12
Alterations of sleep oscillations in Alzheimer's disease: A potential role for GABAergic neurons in the cortex, hippocampus, and thalamus	12
Aquaporin 4 knockout increases complete freund's adjuvant-induced spinal central sensitization	12
Cerebral ischemia-reperfusion causes a down regulation of HCN1 expression via enhancing the nuclear NRSF-HDAC4 gathering that contributes to neuron damage	11
Neuronal activity-dependent myelin repair promotes motor function recovery after contusion spinal cord injury	11
P2X7 receptor in inflammation and pain	11
T-distribution stochastic neighbor embedding for fine brain functional parcellation on rs-fMRI	11
Tacrine accelerates spatial long-term memory via improving impaired neural oscillations and modulating GAD isomers including neuro-receptors in the hippocampus of APP/PS1 AD mice	11
Optogenetic activation of DRN 5-HT neurons induced active wakefulness, not quiet wakefulness	11
Cotinine ameliorates memory and learning impairment in senescent mice	11
LINC02381 contributes to cell proliferation and hinders cell apoptosis in glioma by transcriptionally enhancing CBX5	11
Zebrafish and mouse models for anxiety evaluation – A comparative study with xanthotoxin as a model compound	11
Cannabidiol attenuated the maintenance and reinstatement of extinguished methylphenidate-induced conditioned place preference in rats	11
Resilience in the LPS-induced acute depressive-like behaviors: Increase of CRMP2 neuroprotection and microtubule dynamics in hippocampus	11
The prefrontal cortex and the caudate nucleus respond conjointly to methylphenidate (Ritalin). Concomitant behavioral and neuronal recording study	11
Dexmedetomidine exerts a protective effect on ischemic brain injury by inhibiting the P2X7R/NLRP3/Caspase-1 signaling pathway	11
Mechanism of TREM2/DAP12 complex affecting β-amyloid plaque deposition in Alzheimer's disease modeled mice through mediating inflammatory response	11
Risk of ischemic stroke in patients with COVID-19 infection: A systematic review and meta-analysis	11
Anti-inflammatory and antioxidant effects of astaxanthin following spinal cord injury in a rat animal model	11
Dimethyl fumarate exerts neuroprotection by modulating calcineurin/NFAT1 and NFκB dependent BACE1 activity in Aβ1-42 treated neuroblastoma SH-SY5Y cells	11
Treatment with edaravone improves the structure and functional changes in the hippocampus after chronic cerebral hypoperfusion in rat	11
CZ-7, a new derivative of Claulansine F, promotes remyelination induced by cuprizone by enhancing myelin debris clearance	11
Treadmill exercise alleviates neuronal damage by suppressing NLRP3 inflammasome and microglial activation in the MPTP mouse model of Parkinson’s disease	11
Plasmalogen in the brain: Effects on cognitive functions and behaviors attributable to its properties	11
VSIG4 alleviates intracerebral hemorrhage induced brain injury by suppressing TLR4-regulated inflammatory response	11
RETRACTED: Knockdown EZH2 attenuates cerebral ischemia-reperfusion injury via regulating microRNA-30d-3p methylation and USP22	11
Inspiration for the prevention and treatment of neuropsychiatric disorders: New insight from the bone-brain-axis	10
LINC00511 knockdown suppresses glioma cell malignant progression through miR-15a-5p/AEBP1 axis	10
Glycyrrhizic acid protects juvenile epileptic rats against hippocampal damage through activation of Sirtuin3	10
PPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related ge	10
Application of neurotrophic factor-secreting cells (astrocyte - Like cells) in the in-vitro Alzheimer’s disease-like pathology on the human neuroblastoma cells	10
Long noncoding RNA SOX2OT silencing alleviates cerebral ischemia-reperfusion injury via miR-135a-5p-mediated NR3C2 inhibition	10
Long non-coding RNA ATXN8OS promotes ferroptosis and inhibits the temozolomide-resistance of gliomas through the ADAR/GLS2 pathway	10
Agmatine ameliorates manifestation of depression-like behavior and hippocampal neuroinflammation in mouse model of Alzheimer’s disease	10
Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats	10
Neurogenic and cognitive enhancing effects of human dental pulp stem cells and its secretome in animal model of hippocampal neurodegeneration	10
Manifestations and mechanisms of central nervous system damage caused by SARS-CoV-2	10
Effect of morphine exposure on novel object memory of the offspring: The role of histone H3 and ΔFosB	10
Xenon modulates the GABA and glutamate responses at genuine synaptic levels in rat spinal neurons	10
Theta burst stimulation ameliorates symptoms of experimental autoimmune encephalomyelitis and attenuates reactive gliosis	10
Effect of metformin in autistic BTBR T + Itpr3tf/J mice administered a high-fat diet	10
Neuroprotective effects of auraptene following traumatic brain injury in male rats: The role of oxidative stress	10
NLRP3 inflammasome deficiency attenuates cerebral ischemia-reperfusion injury by inhibiting ferroptosis	10
RETRACTED: MicroRNA-16-5p/BTG2 axis affects neurological function, autophagy and apoptosis of hippocampal neurons in Alzheimer's disease	10
High-frequency spinal cord stimulation treatment attenuates the increase in spinal glutamate release and spinal miniature excitatory postsynaptic currents in rats with spared nerve injury-induced neur	10
JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE	10
Interaction between zinc, the GPR39 zinc receptor and the serotonergic system in depression	10
Glucokinase in stellate ganglia cooperates with P2X3 receptor to develop cardiac sympathetic neuropathy in type 2 diabetes rats	10
IL-1R-/- alleviates cognitive deficits through microglial M2 polarization in AD mice	10
RETRACTED: The antidepressant effects of L-arginine on chronic mild stress-induced depression by augmenting the expression of brain-derived neurotrophic factor in rats	10
Pramipexole regulates depression-like behavior via dopamine D3 receptor in a mouse model of Parkinson’s disease	10
Angiotensin II induces cognitive decline and anxiety-like behavior via disturbing pattern of theta-gamma oscillations	10
Targeting the TLR4/NF-κB pathway in β-amyloid-stimulated microglial cells: A possible mechanism that oxysophoridine exerts anti-oxidative and anti-inflammatory effects in an in vitro model of Alzheime	10
Skin-derived precursor Schwann cells protect SH-SY5Y cells against 6-OHDA-induced neurotoxicity by PI3K/AKT/Bcl-2 pathway	10
Critical role of dysfunctional mitochondria and defective mitophagy in autism spectrum disorders	10
RETRACTED: MicroRNA-29a-3p strengthens the effect of dexmedetomidine on improving neurologic damage in newborn rats with hypoxic-ischemic brain damage by inhibiting HDAC4	10
Parkin mutation decreases neurite complexity and maturation in neurons derived from human fibroblasts	10
Brain–heart communication in health and diseases	10
ZFP36 protects against oxygen-glucose deprivation/reoxygenation-induced mitochondrial fragmentation and neuronal apoptosis through inhibiting NOX4-DRP1 pathway	10
Extracellular vesicle-derived miR-511–3p from hypoxia preconditioned adipose mesenchymal stem cells ameliorates spinal cord injury through the TRAF6/S1P axis	10
MicroRNA-214–5p involves in the protection effect of Dexmedetomidine against neurological injury in Alzheimer’s disease via targeting the suppressor of zest 12	10
Electroacupuncture alleviates ischaemic brain injury by regulating the miRNA-34/Wnt/autophagy axis	10
Neuroprotective effect of low-intensity transcranial ultrasound stimulation in endothelin-1-induced middle cerebral artery occlusion in rats	10
Sex-dependent effects of chronic fluoxetine exposure during adolescence on passive avoidance memory, nociception, and prefrontal brain-derived neurotrophic factor mRNA expression	10
Repeated social defeat stress inhibits development of hippocampus neurons through mitophagy and autophagy	9
Activation of the N-methyl-D-aspartate receptor contributes to orofacial neuropathic and inflammatory allodynia by facilitating calcium-calmodulin-dependent protein kinase II phosphorylation in mice	9
Sigma-1 receptor increases intracellular calcium in cultured astrocytes and contributes to mechanical allodynia in a model of neuropathic pain	9