OOIR: Observatory of International Research

Papers

(The TQCC of Drug Metabolism Reviews is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
The annoying flaws of gerontological research	42
Drug transporters in drug disposition – the year 2022 in review	36
Cell-Biomaterial constructs for wound healing and skin regeneration	33
Enantioselectivity in some physiological and pathophysiological roles of hydroxyeicosatetraenoic acids	29
Differential modulation of cytochrome P450 enzymes by arsenicals in non-human experimental models	26
Mechanisms of intestinal pharmacokinetic natural product-drug interactions	23
New strategy for rational use of antihypertensive drugs in clinical practice in high-altitude hypoxic environments	19
Bioanalytical strategies in drug discovery and development	19
Assessing and mitigating pH-mediated DDI risks in drug development – formulation approaches and clinical considerations	17
Rodent genetic models of Ah receptor signaling	15
Cytochrome P450-mediated carbon-carbon bond formation in drug metabolism	15
Transporter-mediated drug-drug interactions: regulatory guidelines, in vitro and in vivo methodologies and translation, special population	13
Biopolymers as promising vehicles for drug delivery to the brain	13
Clinical pharmacokinetics of nebivolol: a systematic review	12
Genetic determinants of paclitaxel-induced peripheral neuropathy: a review of current literature	12
A transcriptional regulatory network of HNF4α and HNF1α involved in human diseases and drug metabolism	11
Metabolic activation of tyrosine kinase inhibitors: recent advance and further clinical practice	11
Scaling factors to inform in vitro - in vivo extrapolation from preclinical and livestock animals: state of the field and recommendations	11
Favipiravir, remdesivir, and lopinavir: metabolites, degradation products and their analytical methods	10
In silico ADME and target prediction studies of Alogliptin as drug molecule	10
Recent advances in drug transporter sciences: highlights from the year 2020	10
Reinforcing our defense or weakening the enemy? A comparative overview of defensive and offensive strategies developed to confront COVID-19	10