Cancer Chemotherapy and Pharmacology

Papers
(The median citation count of Cancer Chemotherapy and Pharmacology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Quantitative proteomics profiling reveals the inhibition of trastuzumab antitumor efficacy by phosphorylated RPS6 in gastric carcinoma125
Pharmacogenomic associations of cyclophosphamide pharmacokinetic candidate genes with 4hydroxycyclophosphamide formation in children with Cancer38
A polo-like kinase 1 inhibitor enhances erastin sensitivity in head and neck squamous cell carcinoma cells in vitro30
Pazopanib and antacids: insights from the WHO pharmacovigilance database30
Population pharmacokinetics of ruxolitinib in children with hemophagocytic lymphohistiocytosis: focus on the drug–drug interactions29
A clinical scoring tool validated with machine learning for predicting severe hand–foot syndrome from sorafenib in hepatocellular carcinoma27
Impact of previous corticosteroid exposure on outcomes of patients receiving immune checkpoint inhibitors for advanced non-small cell lung cancer: a retrospective observational study25
Predictive significance of inflammatory markers and mGPS in metastatic castration-resistant prostate cancer treated with abiraterone or enzalutamide23
Determination of 5-azacitidine in human plasma by LC–MS/MS: application to pharmacokinetics pilot study in MDS/AML patients23
Aprepitant, fosaprepitant and risk of ifosfamide-induced neurotoxicity: a systematic review21
Exposure–response analysis of Camidanlumab tesirine in patients with relapsed or refractory classical Hodgkin lymphoma and non-Hodgkin lymphoma20
Biotransformation and disposition of C14-labeled sonrotoclax ([14C]BGB-11417) in preclinical safety species and characterization of unique contribution from gut microbiome20
Correlation analysis between camrelizumab trough concentration levels and efficacy or safety in East Asian patients with advanced lung cancer20
Pharmacokinetics of cisplatin in the systemic versus hyperthermic intrathoracic or intraperitoneal chemotherapy19
Comment on: Dose adjustment strategy for high dose methotrexate-induced toxicities in pediatric acute lymphoblastic leukemia: based on population PK analysis and exposure toxicity relationship19
Effects of cyclophosphamide related genetic variants on clinical outcomes of adult hematopoietic cell transplant patients18
Plasma clearance of 5-fluorouracil is more influenced by variations in glomerular filtration rate than by uracil concentration18
A case report: capillary leak syndrome in a patient receiving high-dose methotrexate, Tislelizumab and zanubrutinib for CNS lymphoma17
Mirvetuximab soravtansine in ovarian cancer therapy: expert opinion on pharmacological considerations17
A polymorphism in ABCA2 is associated with neutropenia induced by capecitabine in Japanese patients with colorectal cancer17
Correction: HER-2 SMASH17
Retraction Note: NO donor inhibits proliferation and induces apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells16
Development of a population pharmacokinetic/pharmacodynamic model for various oral paclitaxel formulations co-administered with ritonavir and thrombospondin-1 based on data from early phase clinical s16
Advanced statistics identification of participant and treatment predictors associated with severe adverse effects induced by fluoropyrimidine-based chemotherapy16
Pharmacokinetic drug–drug interaction between olaparib and apixaban: a case report15
Population pharmacokinetic analysis of bevacizumab in Japanese cancer patients with proteinuria: a prospective cohort study15
Drug resistance to nelarabine in leukemia cell lines might be caused by reduced expression of deoxycytidine kinase through epigenetic mechanisms15
Pharmacokinetics, safety, tolerability, and feasibility of apatinib in combination with gefitinib in stage IIIB-IV EGFR-mutated non-squamous NSCLC: a drug-drug interaction study15
Efficacy and safety exposure–response analyses of entrectinib in patients with advanced or metastatic solid tumors13
A phase I pharmacokinetic study of copanlisib in Chinese patients with relapsed indolent non-Hodgkin lymphoma13
Assessment of cytochrome P450 3A4-mediated drug–drug interactions for ipatasertib using a fit-for-purpose physiologically based pharmacokinetic model13
Optimized scaling of translational factors in oncology: from xenografts to RECIST13
Anti-tumor efficacy of RAF/MEK inhibitor VS6766 in KRAS-mutated colorectal cancer cells12
Immunoregulatory cyclophilin a improves low-dose chemotherapy with a modulation of the immune tumor microenvironment in experimental models of melanoma B16 and lymphoma EL4 in vivo12
Real-world pharmacokinetics of trametinib in pediatric low-grade glioma12
An interactive dose optimizer based on population pharmacokinetic study to guide dosing of methotrexate in Chinese patients with osteosarcoma12
Phase I trial of ATR inhibitor elimusertib with FOLFIRI in advanced or metastatic gastrointestinal malignancies (ETCTN 10406)12
Optimization of G-CSF dosing schedule in patients treated with eribulin: a modeling approach12
Phase I study of the VEGF/Ang-2 inhibitor BI 836880 alone or combined with the anti-programmed cell death protein-1 antibody ezabenlimab in Japanese patients with advanced solid tumors12
Combination of S-1 and the oral ATR inhibitor ceralasertib is effective against pancreatic cancer cells11
Fluoropyrimidine-associated toxicity and DPYD variants c.85T>C, c.496A>G, and c.1236G>A: impact of haplotype11
Hsp90 inhibition sensitizes DLBCL cells to cisplatin11
Platinum-based chemotherapy in metastatic prostate cancer: what possibilities?11
Emetine, a small molecule natural product, displays potent anti-gastric cancer activity via regulation of multiple signaling pathways11
Effect of fluconazole on the pharmacokinetics of fuzuloparib: an open-label, crossover study in Chinese healthy male volunteers11
Nanotechnology and nanobots unleashed: pioneering a new era in gynecological cancer management – a comprehensive review11
Alternative routes of drug administration: exposure of imatinib using different formulations11
Targeted therapy of angiogenesis using anti-VEGFR2 and anti-NRP-1 nanobodies11
Population pharmacokinetics and pharmacogenetics analyses of imatinib in Chinese patients with chronic myeloid leukemia in a real-world situation10
HMGB1 assists the predictive value of tumor PD-L1 expression for the efficacy of anti-PD-1/PD-L1 antibody in NSCLC10
18β-glycyrrhetinic acid suppresses Lewis lung cancer growth through protecting immune cells from ferroptosis10
Physiologically based pharmacokinetic modeling of ponatinib to describe drug–drug interactions in patients with cancer10
The effect of rifampin on the pharmacokinetics of famitinib in healthy subjects10
Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors10
Aclarubicin: contemporary insights into its mechanism of action, toxicity, pharmacokinetics, and clinical standing10
RETRACTED ARTICLE: New recommendations for reversal of high-dose methotrexate cytotoxicity with folinic acid9
Successful use of Palbociclib combined with Venetoclax and Azacitidine in an adult with refractory/relapsed therapy-related acute myeloid leukemia9
SOX8 promotes cetuximab resistance via HGF/MET bypass pathway activation in colorectal cancer9
Retraction Note: Induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in B[a]P-induced mouse skin tumorigenesis9
Peptides derived from the POU domain of BRN2 show antitumor activity against murine melanoma model cells in vitro and in vivo9
Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole9
Pharmacokinetics, mass balance, and metabolism of [14C]FCN-437c, a selective and potent CDK4/6 inhibitor in humans8
Combined treatment of All-trans retinoic acid with Tamoxifen suppresses ovarian cancer8
A phase 1 study of the combination of BH3-mimetic, navitoclax, and mTORC1/2 inhibitor, vistusertib, in patients with advanced solid tumors8
Population pharmacokinetic and exposure–response analyses of elotuzumab plus pomalidomide and dexamethasone for relapsed and refractory multiple myeloma8
Dihydropyrimidine enzyme activity and its effect on chemotherapy toxicity: importance of genetic testing8
Risk factors of proteinuria and potentially protective effect of renin–angiotensin system inhibitors in patients with renal cell carcinoma receiving axitinib8
A translational model-based approach to inform the choice of the dose in phase 1 oncology trials: the case study of erdafitinib8
Cytidine deaminase enzyme activity is a predictive biomarker in gemcitabine-treated cancer patients8
Pharmacokinetic exposure and treatment outcomes of lenvatinib in patients with renal cell carcinoma and differentiated thyroid carcinoma8
Targeting insulin-like growth factor-1 (IGF-1) by using metformin in non-diabetic metastatic breast cancer female patients: a randomized controlled trial8
Renal function-based versus standard dosing of pemetrexed: a randomized controlled trial8
Evaluating the indotecan–neutropenia relationship in patients with solid tumors by population pharmacokinetic modeling and sigmoidal Emax regressions8
Avermectin B1 mediates antitumor activity and induces autophagy in osteosarcoma through the AMPK/ULK1 signaling pathway8
Application of physiologically based pharmacokinetics modeling in the research of small-molecule targeted anti-cancer drugs8
Mass balance, metabolic disposition, and pharmacokinetics of a novel selective inhibitor of PI3Kδ [14C] SHC014748M in healthy Chinese subjects following oral administration7
PDI inhibitor LTI6426 enhances panobinostat efficacy in preclinical models of multiple myeloma7
Effects of infliximab, an anti-TNF-α, on cyclophosphamide-induced bone marrow toxicity7
PARP1 promotes EGFR-TKI drug-resistance via PI3K/AKT pathway in non-small-cell lung cancer7
Repurposed antipsychotic chlorpromazine inhibits colorectal cancer and pulmonary metastasis by inducing G2/M cell cycle arrest, apoptosis, and autophagy7
A feasibility study of lenvatinib plus pembrolizumab in Japanese patients with advanced solid tumors7
Protective effect of celecoxib against capecitabine induced hand and foot syndrome in patients with colorectal Cancer7
Somatic nuclear auto-antigenic sperm protein sensitizes human breast cancer cells to 5-Fluorouracil7
Gene polymorphisms of TACR1 serve as the potential pharmacogenetic predictors of response to the neurokinin-1 receptor antagonist-based antiemetic regimens: a candidate-gene association study in breas7
Assay performance and stability of uracil and dihydrouracil in clinical practice7
Removal rate of 5-fluorouracil and its metabolites in patients on hemodialysis: a report of two cases of colorectal cancer patients with end-stage renal failure7
Association of VEGFA and CCL4L2 polymorphisms with hand-foot skin reaction and survival of regorafenib in Japanese patients with colorectal cancer7
Phase 1 study of belinostat and adavosertib in patients with relapsed or refractory myeloid malignancies7
Prognostic value of RRM1 and its effect on chemoresistance in pancreatic cancer6
Correction to: Midostaurin drug interaction profile: a comprehensive assessment of CYP3A, CYP2B6, and CYP2C8 drug substrates, and oral contraceptives in healthy participants6
Effects of splicing-regulatory polymorphisms in ABCC2, ABCG2, and ABCB1 on methotrexate exposure in Chinese children with acute lymphoblastic leukemia6
Phase 1 studies of the indenoisoquinolines LMP776 and LMP744 in patients with solid tumors and lymphomas6
A phase Ib study of Oraxol (oral paclitaxel and encequidar) in patients with advanced malignancies6
Pharmacokinetic and bioequivalence study of two capecitabine tablets in Chinese patients with solid tumor cancer6
Integrated exposure–response analysis of efficacy and safety of lurbinectedin to support the dose regimen in small-cell lung cancer6
Overexposure to venetoclax is associated with prolonged-duration of neutropenia during venetoclax and azacitidine therapy in Japanese patients with acute myeloid leukemia6
Phase I pharmacokinetic, safety, and preliminary efficacy study of tiragolumab in combination with atezolizumab in Chinese patients with advanced solid tumors6
Exposure–response analyses of erdafitinib in patients with locally advanced or metastatic urothelial carcinoma6
A phase I trial of the pan-ERBB inhibitor neratinib combined with the MEK inhibitor trametinib in patients with advanced cancer with EGFR mutation/amplification, HER2 mutation/amplification, HER3/4 mu6
Clinical significance of KL-6 in immune-checkpoint inhibitor treatment for non-small cell lung cancer6
Veratricplatin inhibits the progression of hypopharyngeal squamous cell carcinoma FaDu cells in vitro and in vivo6
Population pharmacokinetic and exposure-toxicity analyses of nab-paclitaxel after pegylated recombinant human granulocyte colony-stimulating factor administration in patients with metastatic breast ca6
Cabozantinib-induced serum creatine kinase elevation and rhabdomyolysis: a retrospective case series6
A phase I study of MLN4924 and belinostat in relapsed/refractory acute myeloid leukemia or myelodysplastic syndrome6
Ruthenium–dihydroartemisinin complex: a promising new compound for colon cancer prevention via G1 cell cycle arrest, apoptotic induction, and adaptive immune regulation6
Phase I study to assess the effect of adavosertib (AZD1775) on the pharmacokinetics of substrates of CYP1A2, CYP2C19, and CYP3A in patients with advanced solid tumors6
Pazopanib pharmacokinetically guided dose optimization in three cancer patients with gastrointestinal resection6
Clinical outcomes and response to chemotherapy in a cohort of pancreatic cancer patients with germline variants of unknown significance (VUS) in BRCA1 and BRCA2 genes6
Adaptive dosing of sunitinib in a metastatic renal cell carcinoma patient: when in silico modeling helps to go quicker to the point6
Bioequivalence, food effect and comparative pharmacokinetics of SUVN-1105, a novel granule formulation of abiraterone acetate, to Zytiga in healthy male subjects5
The effects of pazopanib on doxorubicin pharmacokinetics in children and adults with non-rhabdomyosarcoma soft tissue sarcoma: a report from Children’s Oncology Group and NRG Oncology study ARST13215
Characterization of exposure–response relationships of ipatasertib in patients with metastatic castration-resistant prostate cancer in the IPATential150 study5
Variations in serum concentrations of sunitinib and its metabolites in patients receiving long-term sunitinib treatment5
Evaluation of cytogenetic and molecular markers with MTX-mediated toxicity in pediatric acute lymphoblastic leukemia patients5
Non-linear IV pharmacokinetics of the ATR inhibitor berzosertib (M6620) in mice5
Therapeutic drug monitoring of immune checkpoint inhibitors: based on their pharmacokinetic properties and biomarkers5
Correction to: Phase I study of the anti‑TIGIT antibody tiragolumab in combination with atezolizumab in Japanese patients with advanced or metastatic solid tumors5
Correction to: An IQ consortium analysis of starting dose selection for oncology small molecule first‑in‑patient trials suggests an alternative NOAEL‑based method can be safe while reducing time to th5
A phase I dose escalation, dose expansion and pharmacokinetic trial of gemcitabine and alisertib in advanced solid tumors and pancreatic cancer5
Phase I study of pegylated liposomal doxorubicin and cisplatin in patients with advanced osteosarcoma5
Idiopathic hyperammonemic encephalopathy secondary to gemcitabine–cisplatin treatment5
SMAGP regulates doxorubicin sensitivity in triple-negative breast cancer cells via modulating mitochondrial respiration5
Prospective validation of an equation based on plasma cystatin C for monitoring the glomerular filtration rate in children treated with cisplatin or ifosfamide for cancer5
The Gustave Roussy Immune score is a powerful biomarker for predicting therapeutic resistance to chemotherapy in gastric cancer patients5
Cabozantinib exposure–response analysis for the phase 3 CheckMate 9ER trial of nivolumab plus cabozantinib versus sunitinib in first-line advanced renal cell carcinoma5
A case report of typhlitis during novel use of ropidoxuridine–capecitabine–radiotherapy for treatment-naïve rectal cancer5
Clinical pharmacology and therapeutic applications of talazoparib: a comprehensive review5
Prediction of ROS1 and TRKA/B/C occupancy in plasma and cerebrospinal fluid for entrectinib alone and in DDIs using physiologically based pharmacokinetic (PBPK) modeling approach5
Differential tumor inhibitory effects induced by HER3 extracellular subdomain-specific mouse monoclonal antibodies5
Targeting pan-essential pathways in cancer with cytotoxic chemotherapy: challenges and opportunities5
Expression of molecular markers and synergistic anticancer effects of chemotherapy with antimicrobial peptides on glioblastoma cells5
Effects of a novel toll-like receptor 4 antagonist IAXO-102 in a murine model of chemotherapy-induced gastrointestinal toxicity5
Cytotoxic mechanisms of doxorubicin at clinically relevant concentrations in breast cancer cells4
Polatuzumab vedotin pharmacokinetics in a hemodialysis patient with diffuse large B-cell lymphoma4
Development of a novel nomogram for predicting delayed methotrexate excretion following high-dose methotrexate in adult patients with hematologic malignancies4
Berberine chloride suppresses pancreatic adenocarcinoma proliferation and growth by targeting inflammation-related genes: an in silico analysis with in vitro and vivo validation4
ETV1 genetic polymorphisms as a candidate prognosis biomarker of Gastrointestinal stromal tumor4
The effect of liver dysfunction on the pharmacokinetic disposition of belinostat and its five metabolites in patients with advanced cancers4
AKR1C4 regulates the sensitivity of colorectal cancer cells to chemotherapy through ferroptosis modulation4
Assessing pharmacokinetics and drug-drug interactions of the combination therapy of myelofibrosis with ruxolitinib and lenalidomide by a new eco-friendly HPLC method for their simultaneous determinati4
High MCM10 expression mediates TMZ resistance and promotes the progression of glioma4
Quantitative characterization of the effects of fulvestrant alone or in combination with taselisib (PI3Kinase inhibitor) on longitudinal tumor growth in patients with estrogen receptor-positive, HER2-4
A phase I study of the OX40 agonist BGB-A445 with or without tislelizumab, an anti–PD-1 monoclonal antibody, in patients with advanced solid tumors: dose-escalation results4
Association between chemotherapy-induced myelosuppression and curative efficacy of 2-cycle chemotherapy in small cell lung cancer4
Exposure–response analyses for the MET inhibitor tepotinib including patients in the pivotal VISION trial: support for dosage recommendations4
Adjuvant treatment with Capecitabine in patients who received orthotopic liver transplantation with incidental diagnosis of intrahepatic cholangiocarcinoma. Implications on DPYD polymorphisms assessme4
Disulfiram enhances chemotherapeutic effects of doxorubicin liposomes against human hepatocellular carcinoma via activating ROS-induced cell stress response pathways4
Influence of DPYD gene polymorphisms on 5-Fluorouracil toxicities in Thai colorectal cancer patients4
Endoglin as a predictive biomarker for pemetrexed sensitivity in non-small-cell lung cancer: a cellular study4
Evaluation of mycophenolic acid exposure in a patient with immune-related hepatotoxicity caused by nivolumab and ipilimumab therapy for malignant melanoma: a case report4
Intestinal toll-like receptor 4 knockout alters the functional capacity of the gut microbiome following irinotecan treatment4
Anlotinib in cancer therapy: mechanisms of action, clinical applications, and future perspectives4
The landscape of very important pharmacogenes variants and potential clinical relevance in the Chinese Jingpo population: a comparative study with worldwide populations4
The combination of brentuximab vedotin and chidamide synergistically suppresses the proliferation of T-cell lymphoma cells through the enhancement of apoptosis4
Roles of DNA polymerase ζ in the radiotherapy sensitivity and oxidative stress of lung cancer cells4
Genetic polymorphisms as predictive biomarkers of adverse events during preoperative chemotherapy in esophageal cancer4
Larotrectinib-associated withdrawal symptoms resolved following initiation of GLP-1 receptor agonist: a case report4
Vitamin D suppresses CD133+/CD44 + cancer stem cell stemness by inhibiting NF-κB signaling and reducing NLRP3 expression in triple-negative breast cancer4
Continuous 72-h infusion of zosuquidar with chemotherapy in patients with newly diagnosed acute myeloid leukemia stratified for leukemic blast P-glycoprotein phenotype4
Population pharmacokinetics of cisplatin in small cell lung cancer patients guided with informative priors4
A phase IV study evaluating QT interval, pharmacokinetics, and safety following fractionated dosing of gemtuzumab ozogamicin in patients with relapsed/refractory CD33-positive acute myeloid leukemia4
Is age just a number? A population pharmacokinetic study of gemcitabine4
Safety and pharmacokinetics of imaradenant (AZD4635) in Japanese patients with advanced solid malignancies: a phase I, open-label study4
Disulfiram/copper induces antitumor activity against gastric cancer cells in vitro and in vivo by inhibiting S6K1 and c-Myc4
Re-thinking the possible interaction between proton pump inhibitors and capecitabine4
Pharmacokinetics of metronomic temozolomide in cerebrospinal fluid of children with malignant central nervous system tumors4
Exposure-response analysis of asciminib efficacy and safety in patients with chronic myelogenous leukemia in chronic phase4
Entrectinib dose confirmation in pediatric oncology patients: pharmacokinetic considerations4
Comparison of the immunomodulatory potential of platinum-based anti-cancer drugs and anthracyclins on human monocyte-derived cells4
Effect of Metformin on vascular endothelial injury in patients with non-small cell lung cancer treated with chemotherapy combined with bevacizumab4
A phase I study of AZD2171 and Temsirolimus in patients with advanced gynecological malignancies4
TMEM120A-mediated regulation of chemotherapy sensitivity in colorectal cancer cells4
Distribution of therapeutic monoclonal antibodies into ascites in advanced gastric cancer patients with peritoneal metastasis: case reports and literature review4
Clinical results of the EVESOR trial, a multiparameter phase I trial of everolimus and sorafenib combination in solid tumors4
New approach to busulfan dosing in infants and children based on a population pharmacokinetic analysis4
Anti-drug antibodies in the current management of cancer3
Pre-treatment amino acids and risk of paclitaxel-induced peripheral neuropathy in SWOG S02213
A phase 1 and pharmacodynamic study of chronically-dosed, single-agent veliparib (ABT-888) in patients with BRCA1- or BRCA2-mutated cancer or platinum-refractory ovarian or triple-negative breast canc3
A sub-pharmacological test dose does not predict individual docetaxel exposure in prostate cancer patients3
Adavosertib (AZD1775) does not prolong the QTc interval in patients with advanced solid tumors: a phase I open-label study3
A phase 1b study of erlotinib and momelotinib for the treatment of EGFR-mutated, tyrosine kinase inhibitor-naive metastatic non-small cell lung cancer3
A three-marker signature identifies senescence in human breast cancer exposed to neoadjuvant chemotherapy3
Extracellular vesicles carry miR-27a-3p to promote drug resistance of glioblastoma to temozolomide by targeting BTG23
Exploring the effect of BRCA1/2 status on chemotherapy-induced hematologic toxicity in patients with ovarian cancer3
Impact of pre-hydration duration on high-dose methotrexate induced nephrotoxicity in childhood acute lymphoblastic leukaemia in resource constraint centers: a randomized crossover study3
Impact of ALDH1A1 and NQO1 gene polymorphisms on the response and toxicity of chemotherapy in Bangladeshi breast cancer patients3
WT161, a selective HDAC6 inhibitor, decreases growth, enhances chemosensitivity, promotes apoptosis, and suppresses motility of melanoma cells3
Absorption, distribution, metabolism, and excretion of [14C]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats3
Model-informed drug repurposing of proton pump inhibitors for the prevention of oxaliplatin induced peripheral neuropathy: A real-world data analysis and pharmacometrics approach3
A phase I study of the ceramide nanoliposome in patients with advanced solid tumors3
Lurbinectedin-induced thrombocytopenia: the role of body surface area3
DPYD genotype should be extended to rare variants: report on two cases of phenotype / genotype discrepancy3
Interactions between natural products and cancer treatments: underlying mechanisms and clinical importance3
A bavachinin analog, D36, induces cell death by targeting both autophagy and apoptosis pathway in acute myeloid leukemia cells3
Substitution of ifosfamide for cyclophosphamide in the TI-CE regimen: pharmacology and dose justification in a patient with refractory metastatic germ-cell tumor post-nephrectomy—A case report3
Dosing chemotherapy in children with obesity: literature review and evaluation of local practices3
Population pharmacokinetics and toxicity correlation analysis of free and liposome-encapsulated doxorubicin in Chinese patients with advanced breast cancer3
Infections occurring following IL6 blockade for the management of cytokine release syndrome in onco-hematology patients3
Progressive erythrocytosis under lenvatinib treatment in patients with advanced hepatocellular carcinoma3
Systemic exposure to cisplatin and paclitaxel after intraperitoneal chemotherapy in ovarian cancer3
Ferroptosis – a potential feature underlying neratinib-induced colonic epithelial injury3
Retraction Note: Atrial natriuretic peptide protects against cisplatin‑induced granulocytopenia3
Clinical implications and chemo-sensitivity of adjuvant chemotherapy in patients with poorly cohesive cells-gastric cancer3
The CNS-penetrating taxane drug TPI 287 potentiates antiglioma activity of the AURKA inhibitor alisertib in vivo3
Physiologically-based pharmacokinetic models versus allometric scaling for prediction of tyrosine-kinase inhibitor exposure from adults to children3
Napabucasin targets resistant triple negative breast cancer through suppressing STAT3 and mitochondrial function3
Inhibition of proteinase-activated receptor 2 (PAR2) decreased the malignant progression of lung cancer cells and increased the sensitivity to chemotherapy3
Role of renin angiotensin system inhibitors and metformin in Glioblastoma Therapy: a review3
Multicenter randomized phase II study on S-1 and oxaliplatin therapy as an adjuvant after hepatectomy for colorectal liver metastases (YCOG1001)3
Landscape analysis of adverse events and dose intensity for FDA approved oncology small molecules3
Correction to: Inhibition of proteinase-activated receptor 2 (PAR2) decreased the malignant progression of lung cancer cells and increased the sensitivity to chemotherapy3
Excessive vincristine exposure in a child being treated for acute lymphoblastic leukaemia with underlying Dubin–Johnson syndrome: a case report3
Population pharmacokinetic modelling of imatinib in healthy subjects receiving a single dose of 400 mg3
Osthole inhibits malignant phenotypes and induces ferroptosis in KRAS-mutant colorectal cancer cells via suppressing AMPK/Akt signaling3
UGT1A4 Polymorphism is not Associated with a Clinically Relevant Change in Giredestrant Exposure3
Successful desensitization in a patient with metastatic colorectal cancer presenting with regorafenib-mediated fix drug eruption3
Model-informed development of a cost-saving dosing regimen for enfortumab vedotin3
A comparison of the renal function biomarkers serum creatinine, pro-enkephalin and cystatin C to predict clearance of pemetrexed3
Pharmacokinetics, mass balance, and metabolism of [14C]envonalkib (TQ-B3139), a novel ALK tyrosine kinase inhibitor, in healthy Chinese subjects2
A bioequivalence study of trifluridine/tipiracil tablets in Chinese metastatic colorectal cancer patients under fed conditions2
Population pharmacokinetics and exposure-response analysis of durvalumab in combination with gemcitabine and cisplatin in patients with advanced biliary tract cancer2
Editorial Expression of Concern for: Induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in B[a]P-induced mouse skin tumorig2
The role of alternative splicing in lung cancer2
Relative bioavailability of fedratinib through various alternative oral administration methods in healthy adults2
Dose-dependent bioavailability, absorption-rate limited elimination, and tissue distribution of the ATR inhibitor BAY-1895344 (elimusertib) in mice2
Are novel oral oncolytics underdosed in obese patients?2
Effect of massive ascites on ramucirumab pharmacokinetics in patients with gastrointestinal cancers: a population pharmacokinetic analysis2
Ivermectin induces nonprotective autophagy by downregulating PAK1 and apoptosis in lung adenocarcinoma cells2
Correction to: Evaluation of the absolute oral bioavailability of the anaplastic lymphoma kinase/c-ROS oncogene 1 kinase inhibitor lorlatinib in healthy participants2
Population pharmacokinetics analysis of camidanlumab tesirine in patients with relapsed or refractory Hodgkin lymphoma and non-Hodgkin lymphoma2
Itraconazole interferes in the pharmacokinetics of fuzuloparib in healthy volunteers2
Safety, antitumor activity, and pharmacokinetics of dostarlimab, an anti-PD-1, in patients with advanced solid tumors: a dose–escalation phase 1 trial2
Rituximab biosimilar for the treatment of diffuse large B-cell lymphoma: a phase 3 randomized study in India2
Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data2
Correction to: A phase I, first-in-human study of TAK-164, an antibody–drug conjugate, in patients with advanced gastrointestinal cancers expressing guanylyl cyclase C2
Evaluation of urinary vanin-1 for the early prediction of cisplatin-induced acute kidney injury during neoadjuvant chemotherapy for esophageal cancer2
Long non-coding RNAs: controversial roles in drug resistance of solid tumors mediated by autophagy2
An update on antibody–drug conjugates in urothelial carcinoma: state of the art strategies and what comes next2
Evaluation of FTO polymorphism in 6-mercaptopurine related intolerance in children with acute lymphoblastic leukemia2
HER-2 SMASH2
Pharmacokinetics of UGN‑102, an investigational mitomycin‑containing reverse thermal gel for the treatment of non-muscle invasive bladder cancer2
A PK-PD model linking biomarker dynamics to progression-free survival in patients treated with everolimus and sorafenib combination therapy, EVESOR phase I trial2
Pharmacokinetics of trastuzumab and its efficacy and safety in HER2-positive cancer patients2
Alterations in pharmacogenetic genes and their implications for imatinib resistance in Chronic Myeloid Leukemia patients from an admixed population2
Plasma endothelin-1 may predict bevacizumab-induced proteinuria in patients with colorectal cancer2
Andrographolide inhibits Burkitt’s lymphoma by binding JUN and CASP3 proteins2
Selinexor targeting XPO1 promotes PEG3 nuclear accumulation and suppresses cholangiocarcinoma progression2
Starting dose selection of palbociclib in Chinese patients with breast cancer based on population kinetic–pharmacodynamic model of neutropenia2
Dose adjustment strategy for high-dose methotrexate-induced toxicities in pediatric acute lymphoblastic leukemia: based on population PK analysis and exposure-toxicity relationship2
Targeting Wee1 kinase to suppress proliferation and survival of cisplatin-resistant head and neck squamous cell carcinoma2
0.17116808891296