Intensive Care Medicine

Article	Citations
Obituary and tribute to Professor J. Randall Curtis (Randy)	723
Basic ultrasound skill for intensivists: future scope for expansion of the recommendations of the European Society of Intensive Care Medicine	242
Weaning strategy in patients at low-to-medium risk of extubation failure	239
Workplace equity for clinicians with a disability: why it matters for all	207
Personalized oxygen targets are needed for extracorporeal membrane oxygenation	183
Preventing stress ulcer bleeding	174
Quantifying benefit and harm of extracorporeal life support in cardiogenic shock complicating acute myocardial infarction	165
Close collaboration between pathologists and intensivists to understand (not just) coronavirus disease	157
The certainty of parental love vs. the uncertainty of a “best” decision	156
Pitfalls in the use of microcirculation as a resuscitation goal	151
ICU venous thromboembolism prophylaxis: revisiting external validity, vulnerable subgroups, and diagnostic standards, with future directions. Authors' reply	144
Norepinephrine dose and concentration reporting: a closer look at the fine print	135
Exposure to ambient air pollutants and acute respiratory distress syndrome risk in sepsis	132
Variation in intensive care unit beds capacity in China from 2007 to 2021	130
Status epilepticus in the ICU	117
The UNDERSCORE for RRT weaning prediction: promising but not yet ready to unplug. Author's reply	113
Hemodynamic and neurological presentations of invasive meningococcal disease in adults: a nationwide study across 100+ French ICUs	108
Persistent signs of poisoning after massive drug ingestion: move the ultrasound probe to the stomach	106
Comparing intravascular and surface cooling methods: a critical look at outcomes for out-of-hospital cardiac arrest patients—author's reply	102
SHAP model explainability in ECMO–PAL mortality prediction: a critical analysis	98
A double plea for dyspnea as the next great cause of all ICU professions and for caution about the dyspnea-breathlessness equivalence	98
Optimal oxygen and mean arterial blood pressure targets after cardiac arrest	97
Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis	96
Correction: Expanding the role of PoCUS in tailoring diuretic strategies for congestion management in critical care	89
ICU communication: ‘state of the art’	86

Major adverse kidney events as an endpoint in acute kidney injury trials: is it time for a RE-MAKE?	85
Age and associated outcomes among patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory failure: analysis of the Extracorporeal Life Support Organization registry	84
The ultrasound of silence	84
Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury	83
Left ventricular diastolic dysfunction is prevalent but not associated with mortality in patients with septic shock	81
Lung-protective sedation: moving toward a new paradigm of precision sedation	78
18F-fluorodeoxyglucose positron emission tomography/computed tomography differentiates between pneumonia and atelectasis in a mechanically ventilated patient	76
Nicotine patches in patients on mechanical ventilation for severe COVID-19: a randomized, double-blind, placebo-controlled, multicentre trial	75
Using the helmet	75
Staircase strategy, tier-three therapies, and effects on outcome in traumatic brain injured patients: the Triple-T TBI study	74
Mental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort study	74
Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions	72
Serum sickness: a mimic of septic shock	68
Sequencing interventions in ARDS: the critical role of timing and order in standardized management	67
Weaning of neuromuscular patients: the reality is probably somewhere in between. Author’s reply	65
Reassessing open lung ventilation in ARDS: an updated meta-analysis of the 2023 ESICM guidelines highlights risks of routine use and supports individualized strategies	64
Family-administered delirium screening improves satisfaction among ICU caregivers: a prospective cohort study	64
Severe Pneumocystis jirovecii pneumonia: time to reassess our practices	64
Effects of PEEP on ICP in ABI patients and its relationship with etiology	63
Plasminogen supplementation reverses fibrinolytic insufficiency in sepsis-induced disseminated intravascular coagulation: a pilot study	63
Author Correction: Cyclosporine versus placebo pretreatment of brain-dead donors and kidney graft function (Cis-A-Rein trial): a multicenter, double-blind, randomized, controlled trial	62
Frailty in intensive care medicine must be measured, interpreted and taken into account!	60
No ventilation, no ARDS: insights from four-dimensional computed tomography as dynamic imaging	60
Measuring patient’s effort on the ventilator	59
Greenery and outdoor facilities to improve the wellbeing of critically ill patients, their families and caregivers: things to consider	58
Correction to: Noninvasive respiratory support in intensive care medicine	57
Beyond inflammation: the role of metabolic dysregulation in sepsis diagnosis and treatment	57
“Fake” or real hypoxia?: A brainy dilemma	56
From online lessons to bedside insight: learning through the ESICM fellowship experience	56
Retraction Note: Influence of nimodipine and nifedipine on intrapulmonary shunting – a comparison to other vasoactive drugs	56
Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study	56
Five-year mortality and functional trajectories in older survivors of intensive care compared to the general population	56
Rapid temperature increases under isoflurane sedation	55
Dichotomy between ventilator associated-pneumonia/tracheobronchitis: did you ask the lung its opinion? Author's reply	55
Central venous pressure not appropriate to guide volume administration in patients with high-risk pulmonary embolism	54
The role of pleural pressure and airway closure during mechanical ventilation. Author's reply	53
A call to measure family presence in the adult intensive care unit	52
NeuroWatch in acute respiratory distress syndrome: time to tune strategies	52
A common longitudinal intensive care unit data format (CLIF) for critical illness research	51
What’s new in intensive care: disease tolerance	51
Heart–lungs interactions in mechanically ventilated patients: physiology and clinical implications	51
Simultaneous polymicrobial obstructive pyelonephritis and gastrointestinal bleeding revealing ureteroenteric fistula	51
Visco-elastic testing in traumatic bleeding	50
The challenge of pharmacological thromboprophylaxis in ICU patients: anti-FXa activity does not constitute a simple solution	50
Haemoglobin buffering capacity: the missing variable in transfusion physiology after acute brain injury	50
Less is more. Atmospheric and environmental stakes - sedate with care	50
Humanizing Delirium Care	49
Effects of small volume resuscitation with hypertonic saline on body water distribution in ICU patients after cardiac surgery	48
Relationship of multidrug-resistant bacterial colonization and immune status of patients in the ICU	48
Correction: Determinants of fluid use and the association between volume of fluid used and effect of balanced solutions on mortality in critically ill patients: a secondary analysis of the BaSICS tria	47

Management of diabetic ketoacidosis	47
Role of PEEP on the prognostic performance of the ROX index in hypoxemic respiratory failure due to COVID-19: any further gain in outcome prediction?	46
How can assessing hemodynamics help to assess volume status?	46
Severe community-acquired pneumonia: current concepts and controversies	46
Introduction to an intensive care recycling program	46
Should we move beyond the concept of fluid responsiveness?	45
Frailty is crucial in FORECASTing outcomes in critical care	45
B-ICONIC vs. Reality: The Feasibility Gap in Neuro-Ultrasound Recommendations and Achievability. Authors’ reply	45
Epistemology of the error: Kant, Shakespeare, and the intensive care unit	44
Septic shock secondary to a rat-bite fever	44
Central venous-minus-arterial PCO2 to arterial-minus-central venous O2 content ratio is tricky tool to solve the puzzle of lactate sources. Author’s reply	44
Ten myths about Albumin: don’t forget the endothelium. Author’s reply	43
Which issues should be addressed in future trials regarding the use of corticosteroids in community acquired pneumonia? A survey of REMAP-CAP investigators	43
Identifying distinct clusters of ICU survivors by integrating demographic, pre-admission quality of life, and clinical data: a large prospective cohort study	43
Head up, face down—a practical framework for proning brain-injured patients with ARDS	43
The role of pleural pressure on fluid dynamics and responsiveness	42
Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults	42
Left atrial reservoir strain: an essential tool for evaluating left ventricular diastolic dysfunction in 2025	42
Disorders of consciousness diagnosis, interventions, and prognostication for the intensivist: Report of the 2025 ISICEM roundtable	42
Sepsis subphenotypes, theragnostics and personalized sepsis care	42
Awareness of dying: adjustments in family relationships at the end of life	41
Lung and diaphragm protective ventilation guided by the esophageal pressure	41
Reevaluating definitions and modifiable factors in persistent severe acute kidney injury	41
Correspondence on "Using toxidromes in the ICU"	41
High versus low positive end-expiratory pressure during noninvasive ventilation for hypoxemic respiratory failure: balancing efficacy and lung protection—author’s reply	41
Effect of albumin bolus therapy on vasopressor requirement after cardiac surgery	40
What really matters with thrombocytopenia: absolute value, timing, etiology or management? Author's reply	40
Building a better machine learning model of extubation for neurocritical care patients. Author’s reply	40
Portal venous gas on point-of-care ultrasound	40
Multiple intracardiac thrombi in a patient with extracorporeal membrane oxygenation	40
Kidney replacement therapy in critically ill obese patients: an urgent call for precision and evidence-based practice!	40
Intensive Care admission aiming at organ donation as a duty of the intensivist: every organ, every time	40
Correction: Association of hospital and intensive care unit occupancy and non-admission to the intensive care unit decisions: a retrospective cohort study	39
Penicillin allergy assessment and testing: worth the risk in critically ill patients	38
Beyond the numbers: do nomograms capture the complexity of RRT dosing? Author’s reply	38
Microcirculation information in clinical decision making: Rome wasn't built in a day	38
Treatment of positive catheter tip culture without bloodstream infections in critically ill patients. A case-cohort study from the OUTCOMEREA network	38
Double sequential external defibrillation for refractory ventricular fibrillation	37
Can the terms “low resource setting” and “low-income country” be used interchangeably in the context of intensive care medicine?	37
Between two worlds: from ESICM lives back to my ICU—a perspective from Tunisia	36
Optimising aerosolized therapies in critically ill patients	36
Noninvasive ventilation on reintubation in patients with obesity and hypoxemic respiratory failure following abdominal surgery: a post hoc analysis of a randomized clinical trial	36
Caring for the dying patient in ICU	35
Ten tips on sepsis-induced thrombocytopenia	35
Ten reasons for the presence of pharmacy professionals in the intensive care unit	35
Renal replacement therapy initiation strategies in comatose patients with severe acute kidney injury: a secondary analysis of a multicenter randomized controlled trial	35
Selective digestive decontamination- Not sure	35
Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome	34
Head-to-toe bedside ultrasound for adult patients on extracorporeal membrane oxygenation	34
Monocyte HLA-DR expression in septic shock patients: insights from a 20-year real-world cohort of 1023 cases	34
Long-term outcomes of intensive care unit delirium	33
Correction: ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia	33
Consumptive coagulopathy: how low-dose unfractionated heparin can prevent bleeding complications during extracorporeal life support	33
ECMO PAL: using deep neural networks for survival prediction in venoarterial extracorporeal membrane oxygenation	33
Melatonin for prevention of delirium in patients receiving mechanical ventilation in the intensive care unit: a multiarm multistage adaptive randomized controlled clinical trial (DEMEL)	33
Long-term survival comparison of patients admitted to the intensive care unit following in-hospital cardiac arrest in perioperative and ward settings. A multicentre retrospective cohort study	32
Bronchoscopy for diagnosis of ventilator-associated pneumonia	32
Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis	31
Restrictive nutrition in shock: reassuring renal signals—but no proof of safety	31
Tracheal intubation in critically ill adults with a physiologically difficult airway. An international Delphi study	31
Critical insights into venoarterial extracorporeal membrane oxygenation outcomes in immunocompromised patients: addressing uncertainties in cause of death and treatment strategies. Author’s reply	31
ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia	31
Targeting inflammation in traumatic injury: entering a new era	31
Effect of albumin bolus therapy on vasopressor requirement after cardiac surgery? Author’s reply	30
Integrating multidisciplinary expertise in postoperative noninvasive ventilation management. Authors’ reply	30
Hemoadsorption in septic shock – PRO	30
Terlipressin use in HRS-AKI and respiratory failure	30
Bronchoscopic examination of an invasive aspergillosis in acute myeloid leukemia	30
Driving pressure as a target for lung protective strategies: from ARDS critically-ill patients to the operating room—Lessons from the IMPROVE-2 Trial	29
Delirium in ICU and Macbeth’s dagger: author’s reply	29
AI in neurocritical care: what to expect	29
Subphenotypes in critical illness: a priori biological rationale is key. Author’s reply	29
Bridging the gap: implementing ESICM end-of-life care guidelines in resource-limited settings	29
What intensivists need to know about cytomegalovirus infection in immunocompromised ICU patients	28
Acute kidney injury and chronic kidney disease in the aging critically ill patient	28
On acid-base bilingualism	28
Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software	28
Understanding buffering of metabolic acidosis in critical illness	27
Critical care in hematologic emergencies	27
Plasma exchange in septic shock: are we ready for prime time? PRO	27

When capacity exceeds justification: technology, proportionality, and care in the ICU	27
Alveolar gas equation and its clinical implications	27
Unlocking consciousness through right median nerve stimulation. Has a potential cure arrived at our doorstep?	27
Ups and downs of cerebral autoregulation in the intensive care unit: why should we care?	27
Accuracy of continuous glucose monitoring systems in intensive care unit patients: a scoping review	26
How to approach a patient hospitalized for pneumonia who is not responding to treatment?	26
Open-source clinical classifiers for ARDS: democratizing precision or diluting biology?	26
Managing blood glucose control in the intensive care unit	26
Current standard of care for septic shock	26
Acute kidney injury	26
Dr Rick van Saene 1946–2026	26
Ecological effects of selective oral decontamination on multidrug-resistance bacteria acquired in the intensive care unit: a case–control study over 5 years	26
Analgesia as part of the orotracheal intubation induction sequence. Author's reply	25
Low versus standard calorie and protein feeding and renal dysfunction in ventilated adults with shock: a NUTRIREA-3 post hoc analysis	25
Caring for frail patients in the ICU: a multidimensional approach	25
Come hell or high water: climate change through the lens of neurocritical care	25
Human albumin solution for on-pump cardiac surgery: benefit or burden? Author’s reply	25
Hyperoxia and traumatic brain injury: time to stop cooking the books?	25
High and intermediate risk pulmonary embolism in the ICU	25
Coronavirus disease 2019	25
Characteristics of co-infection and secondary infection amongst critically ill COVID-19 patients in the first two waves of the pandemic	25
Reusable versus single-use ICU equipment: what’s the environmental footprint?	25
Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM	25
Antibiotic therapy for severe bacterial infections	25
Obituary and tribute to Professor Tobias Welte	25
Massive gaseous embolism during cardiopulmonary resuscitation for massive hemoptysis in a COVID-19-associated pulmonary aspergillosis	25
Early ICU mobilisation predicting functional impairment at hospital discharge. Author's reply	24
How to optimize extubation?	24
Contemporary management of major haemorrhage in critical care	24
Heterogeneity in a meta-analysis: randomized controlled trials versus observational studies	24
Ceremonial purification: which rite is right in liver failure?	24
Prevention of upper gastrointestinal bleeding in critical illness	24
Author Correction: Current standard of care for septic shock	24
Confusion regarding the use of Natural Language Processing in ICU delirium assessment. Author’s reply	24
The dawn of target trials in intensive care: time to move beyond association is not causation	24
Using ultrasound in ICU	24
Deploying AI in the ICU: learning from successes and failures	23
Challenges for a broad international implementation of the current severe community-acquired pneumonia guidelines	23
Equity in patient care in the intensive care unit	23
Clinical governance in intensive care medicine	23
Monitoring cardiac output	23
Immunosuppressive treatment in solid organ transplant critically ill patients: still an unanswered question?	23
Retraction Note: Phosphodiesterase-inhibitors enoximone and piroximone in cardiac surgery: influence on platelet count and function	23
Neuromonitoring for prognostication under ECMO	22
Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial	22
Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial	22
Preventing acute kidney injury and its longer-term impact in the critically ill	22
Sex representation within intensive care trials in Australia and New Zealand	22
Central venous pressure (CVP)	22
Reconsidering transfusion thresholds in traumatic brain injury with multiple trauma: implications from the HEMOTION sub-study	22
Challenges and strategies in the care of older adults across the continuum of intensive and post-intensive care medicine	22
Delirium Related to Sedation: Prevention Strategies and Patient Perspectives	21
Unraveling the enigma of genetics and phenotypes in ARDS	21
During the storm	21
Human albumin solution for on-pump cardiac surgery: benefit or burden?	21
REMAP-CAP corticosteroids: yet, another swing of the pendulum?	21
Driving pressure: pitfalls of methods that do not use esophageal pressure measurement	21
War, from the inside	21
The role of inferior vena cava in predicting fluid responsiveness	21
Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's reply	21
The paradox of post-intensive care unit physical therapy	21
Gymnopédie: music in the ICU	21
Respective roles of hypercapnia and acidosis in acute distress respiratory syndrome	21
Bidirectional ventricular tachycardia, a very rare and severe complication of digoxin poisoning	21
Validation of the “invasive pulmonary aspergillosis in immunocompromised patients with acute respiratory failure score” (IPA-GRRR-OH score)	21
The relationship of malnutrition, frailty, and sarcopenia in critical care	21
Update on long-term physical disability after critical illness: the burden of post-intensive care syndrome	20
Correction: Variation in intensive care unit beds capacity in China from 2007 to 2021	20
Hypervirulent Klebsiella pneumoniae: watch the eyes	20
Biomarkers and the prediction of acute kidney injury and renal replacement therapy initiation: a dream within a dream	20
Post-sepsis recovery: perspectives on measuring what matters. Author's reply	20
When ‘Early’ isn’t early: time to rethink the timing of mobilization in the ICU	20
Association between driving pressure and mortality may depend on timing since onset of acute respiratory distress syndrome	20
Breaking the dogma: from contraindication to personalized prone positioning in brain-injured patients. Author’s reply	20
Air pollutant exposure and mortality risk of critically ill patients	20
Retraction Note: The new phosphodiesterase inhibitor enoximone in patients following cardiac surgery – pharmacokinetics and influence on parameters of coagulation	19
Onco-nephrology: what the intensivist needs to know	19
Shorter might not always be better: the case for longer antibiotic therapy for Pseudomonas aeruginosa pneumonia	19
Pressure control plus spontaneous ventilation versus volume assist-control ventilation in acute respiratory distress syndrome. A randomised clinical trial	19
Increased risk of central line-associated bloodstream infection in COVID-19 patients associated with dexamethasone but not with interleukin antagonists	19
The second brain in the line of fire: addressing surrogate cognitive dysautoregulation	19
Retraction Note: Right ventricular function and cardiac surgery	19
Persistent severe AKI is bad—where to go now?	19
Shortening antibiotic therapy duration for hospital-acquired bloodstream infections in critically ill patients: a causal inference model from the international EUROBACT-2 database	19
HeartMate 3–related ECG artefact resolved by 40‑Hz low‑pass filtering	19
Correction: Effect modification in a clinical trial should be assessed through interaction terms, not prognostic modelling	18
Correction: ESICM consensus-based recommendations for the management of very old patients in intensive care	18
Using diuretic therapy in the critically ill patient	18
When the heart goes to the wrong side	18
Correction: Influence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2: the multicentre, observational RECOVIDS study	18
Author Correction: Hemoadsorption in septic shock—CON	18
Alveolar gas equation: a metabolic perspective	18
Correction: Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)	18
To mobilise or not to mobilise: is that the right question?	18
Early biomarker detection: fundamentally disputable?	18