Intensive Care Medicine

Article	Citations
Variation in intensive care unit beds capacity in China from 2007 to 2021	582
Obituary and tribute to Professor J. Randall Curtis (Randy)	203
The effects of pantoprazole vs. placebo on 1-year outcomes, resource use and employment status in ICU patients at risk for gastrointestinal bleeding: a secondary analysis of the SUP-ICU trial	187
Effect of proning and recruitment on physio-anatomical variables in COVID-19 pneumonia	180
Time course of physiological variables during inter-hospital helicopter transport of ventilated COVID-19 patients	177
Basic ultrasound skill for intensivists: future scope for expansion of the recommendations of the European Society of Intensive Care Medicine	161
Full enteral nutrition should be avoided among patients with high vasopressor dose and low flow state	150
Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis	145
Weaning strategy in patients at low-to-medium risk of extubation failure	142
Workplace equity for clinicians with a disability: why it matters for all	141
Major adverse kidney events as an endpoint in acute kidney injury trials: is it time for a RE-MAKE?	140
Personalized oxygen targets are needed for extracorporeal membrane oxygenation	133
Preventing stress ulcer bleeding	128
No ventilation, no ARDS: insights from four-dimensional computed tomography as dynamic imaging	115
Quantifying benefit and harm of extracorporeal life support in cardiogenic shock complicating acute myocardial infarction	112
Close collaboration between pathologists and intensivists to understand (not just) coronavirus disease	110
The certainty of parental love vs. the uncertainty of a “best” decision	106
Optimal oxygen and mean arterial blood pressure targets after cardiac arrest	102
Pitfalls in the use of microcirculation as a resuscitation goal	100
Correction to: Noninvasive respiratory support in intensive care medicine	96
ICU venous thromboembolism prophylaxis: revisiting external validity, vulnerable subgroups, and diagnostic standards, with future directions. Authors' reply	91
Norepinephrine dose and concentration reporting: a closer look at the fine print	89
Staircase strategy, tier-three therapies, and effects on outcome in traumatic brain injured patients: the Triple-T TBI study	86
Dose of norepinephrine: the devil is in the details	84
Persistent signs of poisoning after massive drug ingestion: move the ultrasound probe to the stomach	83

Mental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort study	82
Comparing intravascular and surface cooling methods: a critical look at outcomes for out-of-hospital cardiac arrest patients—author's reply	81
A double plea for dyspnea as the next great cause of all ICU professions and for caution about the dyspnea-breathlessness equivalence	79
Beyond inflammation: the role of metabolic dysregulation in sepsis diagnosis and treatment	79
Sequencing interventions in ARDS: the critical role of timing and order in standardized management	77
Severe Pneumocystis jirovecii pneumonia: time to reassess our practices	77
Greenery and outdoor facilities to improve the wellbeing of critically ill patients, their families and caregivers: things to consider	76
Age and associated outcomes among patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory failure: analysis of the Extracorporeal Life Support Organization registry	75
Correction: Expanding the role of PoCUS in tailoring diuretic strategies for congestion management in critical care	74
18F-fluorodeoxyglucose positron emission tomography/computed tomography differentiates between pneumonia and atelectasis in a mechanically ventilated patient	71
Frailty in intensive care medicine must be measured, interpreted and taken into account!	70
Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury	69
Lung-protective sedation: moving toward a new paradigm of precision sedation	65
Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions	65
SHAP model explainability in ECMO–PAL mortality prediction: a critical analysis	63
Nicotine patches in patients on mechanical ventilation for severe COVID-19: a randomized, double-blind, placebo-controlled, multicentre trial	63
Hemodynamic and neurological presentations of invasive meningococcal disease in adults: a nationwide study across 100+ French ICUs	62
Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia	62
Serum sickness: a mimic of septic shock	61
Measuring patient’s effort on the ventilator	60
Exposure to ambient air pollutants and acute respiratory distress syndrome risk in sepsis	58
Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial	57
Anesthetic drugs for rapid sequence intubation: ketamine, but what dose?	55
Using the helmet	55
Reassessing open lung ventilation in ARDS: an updated meta-analysis of the 2023 ESICM guidelines highlights risks of routine use and supports individualized strategies	54
Left ventricular diastolic dysfunction is prevalent but not associated with mortality in patients with septic shock	54
Status epilepticus in the ICU	54
Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study	54
Should we move beyond the concept of fluid responsiveness?	53
B-ICONIC vs. Reality: The Feasibility Gap in Neuro-Ultrasound Recommendations and Achievability. Authors’ reply	53
“Fake” or real hypoxia?: A brainy dilemma	52
Ten myths about Albumin: don’t forget the endothelium. Author’s reply	52
Relationship of multidrug-resistant bacterial colonization and immune status of patients in the ICU	51
Role of PEEP on the prognostic performance of the ROX index in hypoxemic respiratory failure due to COVID-19: any further gain in outcome prediction?	51
Rapid temperature increases under isoflurane sedation	50
Dichotomy between ventilator associated-pneumonia/tracheobronchitis: did you ask the lung its opinion? Author's reply	50
Central venous pressure not appropriate to guide volume administration in patients with high-risk pulmonary embolism	50
Correction: Determinants of fluid use and the association between volume of fluid used and effect of balanced solutions on mortality in critically ill patients: a secondary analysis of the BaSICS tria	49
NeuroWatch in acute respiratory distress syndrome: time to tune strategies	48
The role of pleural pressure and airway closure during mechanical ventilation. Author's reply	48
A call to measure family presence in the adult intensive care unit	47
Bone marrow necrosis induced by massive Staphylococcus aureus infiltration	47
Head up, face down—a practical framework for proning brain-injured patients with ARDS	46
Retraction Note: Influence of nimodipine and nifedipine on intrapulmonary shunting – a comparison to other vasoactive drugs	46
Identifying distinct clusters of ICU survivors by integrating demographic, pre-admission quality of life, and clinical data: a large prospective cohort study	46
Visco-elastic testing in traumatic bleeding	45
Introduction to an intensive care recycling program	45
Towards evidence-based staffing: the promise and pitfalls of patient-to-intensivist ratios	44
The challenge of pharmacological thromboprophylaxis in ICU patients: anti-FXa activity does not constitute a simple solution	44
Effects of small volume resuscitation with hypertonic saline on body water distribution in ICU patients after cardiac surgery	43

Humanizing Delirium Care	43
Septic shock secondary to a rat-bite fever	42
Five-year mortality and functional trajectories in older survivors of intensive care compared to the general population	42
Central venous-minus-arterial PCO2 to arterial-minus-central venous O2 content ratio is tricky tool to solve the puzzle of lactate sources. Author’s reply	42
Less is more. Atmospheric and environmental stakes - sedate with care	42
Frailty is crucial in FORECASTing outcomes in critical care	42
A common longitudinal intensive care unit data format (CLIF) for critical illness research	41
Ten myths about albumin	41
Management of diabetic ketoacidosis	41
Haemoglobin buffering capacity: the missing variable in transfusion physiology after acute brain injury	41
Correction: Association of hospital and intensive care unit occupancy and non-admission to the intensive care unit decisions: a retrospective cohort study	40
Sepsis subphenotypes, theragnostics and personalized sepsis care	40
Left atrial reservoir strain: an essential tool for evaluating left ventricular diastolic dysfunction in 2025	40
What’s new in intensive care: disease tolerance	40
The role of pleural pressure on fluid dynamics and responsiveness	40
Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults	40
How can assessing hemodynamics help to assess volume status?	40
Reevaluating definitions and modifiable factors in persistent severe acute kidney injury	39
High versus low positive end-expiratory pressure during noninvasive ventilation for hypoxemic respiratory failure: balancing efficacy and lung protection—author’s reply	39
Penicillin allergy assessment and testing: worth the risk in critically ill patients	39
Kidney replacement therapy in critically ill obese patients: an urgent call for precision and evidence-based practice!	38
Awareness of dying: adjustments in family relationships at the end of life	38
Double sequential external defibrillation for refractory ventricular fibrillation	38
Defining basic (lung) ultrasound skills; not so basic after all? Author’s reply	37
Renal replacement therapy initiation strategies in comatose patients with severe acute kidney injury: a secondary analysis of a multicenter randomized controlled trial	36
Selective digestive decontamination- Not sure	36
Correspondence on "Using toxidromes in the ICU"	36
What really matters with thrombocytopenia: absolute value, timing, etiology or management? Author's reply	35
Anesthetic drugs for rapid sequence intubation: ketamine, but what dose? Author’s reply	35
Intensive Care admission aiming at organ donation as a duty of the intensivist: every organ, every time	35
Drugs for advanced life support	35
Correction to: Palliative care interventions in intensive care unit patients	35
Caring for the dying patient in ICU	34
Multiple intracardiac thrombi in a patient with extracorporeal membrane oxygenation	34
Effect of albumin bolus therapy on vasopressor requirement after cardiac surgery	34
Building a better machine learning model of extubation for neurocritical care patients. Author’s reply	33
Long-term outcomes of intensive care unit delirium	33
Correction: ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia	33
Microcirculation information in clinical decision making: Rome wasn't built in a day	32
Head-to-toe bedside ultrasound for adult patients on extracorporeal membrane oxygenation	32
Ten reasons for the presence of pharmacy professionals in the intensive care unit	32
Targeting inflammation in traumatic injury: entering a new era	32
Consumptive coagulopathy: how low-dose unfractionated heparin can prevent bleeding complications during extracorporeal life support	32
Treatment of positive catheter tip culture without bloodstream infections in critically ill patients. A case-cohort study from the OUTCOMEREA network	32
Beyond the numbers: do nomograms capture the complexity of RRT dosing? Author’s reply	32
Noninvasive ventilation on reintubation in patients with obesity and hypoxemic respiratory failure following abdominal surgery: a post hoc analysis of a randomized clinical trial	31
Ten tips on sepsis-induced thrombocytopenia	31
Optimising aerosolized therapies in critically ill patients	31
Lung and diaphragm protective ventilation guided by the esophageal pressure	31
Tracheal intubation in critically ill adults with a physiologically difficult airway. An international Delphi study	30
Bronchoscopy for diagnosis of ventilator-associated pneumonia	30
Melatonin for prevention of delirium in patients receiving mechanical ventilation in the intensive care unit: a multiarm multistage adaptive randomized controlled clinical trial (DEMEL)	30
Long-term survival comparison of patients admitted to the intensive care unit following in-hospital cardiac arrest in perioperative and ward settings. A multicentre retrospective cohort study	30
Undocumented migrants in French intensive care units in 2011–2018: retrospective nationwide study	30
Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis	30
ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia	29
Can the terms “low resource setting” and “low-income country” be used interchangeably in the context of intensive care medicine?	29
Critical insights into venoarterial extracorporeal membrane oxygenation outcomes in immunocompromised patients: addressing uncertainties in cause of death and treatment strategies. Author’s reply	29
Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome	29
ECMO PAL: using deep neural networks for survival prediction in venoarterial extracorporeal membrane oxygenation	29
Monocyte HLA-DR expression in septic shock patients: insights from a 20-year real-world cohort of 1023 cases	29
Effect of albumin bolus therapy on vasopressor requirement after cardiac surgery? Author’s reply	28
Integrating multidisciplinary expertise in postoperative noninvasive ventilation management. Authors’ reply	28
Hemoadsorption in septic shock – PRO	28
Bronchoscopic examination of an invasive aspergillosis in acute myeloid leukemia	28
Terlipressin use in HRS-AKI and respiratory failure	28
Subphenotypes in critical illness: a priori biological rationale is key. Author’s reply	28
Delirium in ICU and Macbeth’s dagger: author’s reply	28
On acid-base bilingualism	28
De-adoption of chlorhexidine oral care and ICU mortality. Authors’ reply	28
Bridging the gap: implementing ESICM end-of-life care guidelines in resource-limited settings	28
Prognostic value of global deep white matter DTI metrics for 1-year outcome prediction in ICU traumatic brain injury patients: an MRI-COMA and CENTER-TBI combined study	28
Caring for frail patients in the ICU: a multidimensional approach	27
What intensivists need to know about cytomegalovirus infection in immunocompromised ICU patients	27
How to approach a patient hospitalized for pneumonia who is not responding to treatment?	27
Managing blood glucose control in the intensive care unit	27
AI in neurocritical care: what to expect	27
Open-source clinical classifiers for ARDS: democratizing precision or diluting biology?	27
Antibiotic therapy for severe bacterial infections	26
Unlocking consciousness through right median nerve stimulation. Has a potential cure arrived at our doorstep?	26

Driving pressure as a target for lung protective strategies: from ARDS critically-ill patients to the operating room—Lessons from the IMPROVE-2 Trial	26
Reusable versus single-use ICU equipment: what’s the environmental footprint?	25
Plasma exchange in septic shock: are we ready for prime time? PRO	25
Acute kidney injury	25
Understanding buffering of metabolic acidosis in critical illness	25
Accuracy of continuous glucose monitoring systems in intensive care unit patients: a scoping review	25
Ecological effects of selective oral decontamination on multidrug-resistance bacteria acquired in the intensive care unit: a case–control study over 5 years	25
High and intermediate risk pulmonary embolism in the ICU	24
Retraction Note: Phosphodiesterase-inhibitors enoximone and piroximone in cardiac surgery: influence on platelet count and function	24
Come hell or high water: climate change through the lens of neurocritical care	24
We are proud of you Jamie	24
Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software	24
Hyperoxia and traumatic brain injury: time to stop cooking the books?	24
Coronavirus disease 2019	24
Analgesia as part of the orotracheal intubation induction sequence. Author's reply	24
Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM	24
Massive gaseous embolism during cardiopulmonary resuscitation for massive hemoptysis in a COVID-19-associated pulmonary aspergillosis	24
Obituary and tribute to Professor Tobias Welte	24
Characteristics of co-infection and secondary infection amongst critically ill COVID-19 patients in the first two waves of the pandemic	23
Early ICU mobilisation predicting functional impairment at hospital discharge. Author's reply	23
Clinical governance in intensive care medicine	23
Correction to: Survival benefit of extracorporeal membrane oxygenation in severe COVID-19: a multi-centre-matched cohort study	23
My advice to the NEXT generation	23
Absence of candidemia in critically ill patients with COVID-19 receiving selective digestive decontamination	23
Sex representation within intensive care trials in Australia and New Zealand	23
Human albumin solution for on-pump cardiac surgery: benefit or burden? Author’s reply	23
Confusion regarding the use of Natural Language Processing in ICU delirium assessment. Author’s reply	23
Delirium Related to Sedation: Prevention Strategies and Patient Perspectives	23
How to optimize extubation?	23
Heterogeneity in a meta-analysis: randomized controlled trials versus observational studies	22
The dawn of target trials in intensive care: time to move beyond association is not causation	22
Incidence and risk factors of mental illness among the spouses of patients with sepsis: a population-based cohort study	22
Using ultrasound in ICU	22
Time-limited trial of intensive care is more than merely life sustaining	22
Ceremonial purification: which rite is right in liver failure?	22
Monitoring cardiac output	22
Ketamine for emergency endotracheal intubation: insights into post-induction hemodynamic instability	22
Prevention of upper gastrointestinal bleeding in critical illness	21
Equity in patient care in the intensive care unit	21
Central venous pressure (CVP)	21
Neuromonitoring for prognostication under ECMO	21
Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial	21
Deploying AI in the ICU: learning from successes and failures	21
Challenges for a broad international implementation of the current severe community-acquired pneumonia guidelines	21
Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial	21
Preventing acute kidney injury and its longer-term impact in the critically ill	20
Contemporary management of major haemorrhage in critical care	20
Respective roles of hypercapnia and acidosis in acute distress respiratory syndrome	20
During the storm	19
Gymnopédie: music in the ICU	19
The next big epidemic? Device shutdowns	19
Correction: Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)	19
Correction: Variation in intensive care unit beds capacity in China from 2007 to 2021	19
Unraveling the enigma of genetics and phenotypes in ARDS	19
Driving pressure: pitfalls of methods that do not use esophageal pressure measurement	19
War, from the inside	19
Correction: Effect modification in a clinical trial should be assessed through interaction terms, not prognostic modelling	19
Correction: Influence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2: the multicentre, observational RECOVIDS study	19
Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's reply	18
Persistent severe AKI is bad—where to go now?	18
Norepinephrine pharmacolexicology: a chronological review of dose reporting and the implications of salt formulations	18
Author Correction: Hemoadsorption in septic shock—CON	18
The role of inferior vena cava in predicting fluid responsiveness	18
Retraction Note: The new phosphodiesterase inhibitor enoximone in patients following cardiac surgery – pharmacokinetics and influence on parameters of coagulation	18
Validation of the “invasive pulmonary aspergillosis in immunocompromised patients with acute respiratory failure score” (IPA-GRRR-OH score)	18
Correction: ESICM consensus-based recommendations for the management of very old patients in intensive care	18
Post-sepsis recovery: perspectives on measuring what matters. Author's reply	18
The relationship of malnutrition, frailty, and sarcopenia in critical care	18
Bidirectional ventricular tachycardia, a very rare and severe complication of digoxin poisoning	18
Human albumin solution for on-pump cardiac surgery: benefit or burden?	18
Correction: Direct assessment of microcirculation in shock: a randomized-controlled multicenter study	18
Shortening antibiotic therapy duration for hospital-acquired bloodstream infections in critically ill patients: a causal inference model from the international EUROBACT-2 database	18
Retraction Note: Right ventricular function and cardiac surgery	18
Onco-nephrology: what the intensivist needs to know	17
REMAP-CAP corticosteroids: yet, another swing of the pendulum?	17
Air pollutant exposure and mortality risk of critically ill patients	17
Shorter might not always be better: the case for longer antibiotic therapy for Pseudomonas aeruginosa pneumonia	17
Pressure control plus spontaneous ventilation versus volume assist-control ventilation in acute respiratory distress syndrome. A randomised clinical trial	17
Clustering analysis of geriatric and acute characteristics in a cohort of very old patients on admission to ICU	17
Hypervirulent Klebsiella pneumoniae: watch the eyes	17
Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting	17
Sex and gender differences in intensive care medicine	17
To mobilise or not to mobilise: is that the right question?	17
Intensive care management of acute-on-chronic liver failure	17
The paradox of post-intensive care unit physical therapy	17
Breaking the dogma: from contraindication to personalized prone positioning in brain-injured patients. Author’s reply	17
Association between driving pressure and mortality may depend on timing since onset of acute respiratory distress syndrome	17
Increased risk of central line-associated bloodstream infection in COVID-19 patients associated with dexamethasone but not with interleukin antagonists	17
Using diuretic therapy in the critically ill patient	17
When ‘Early’ isn’t early: time to rethink the timing of mobilization in the ICU	17
Prognostication model for traumatic brain injury based on age and white matter diffusion metrics in MRI brain. Author’s reply	16
Retraction Note: The effects of pentoxifylline on circulating adhesion molecules in critically ill patients with acute renal failure treated by continuous veno-venous hemofiltration	16
The TARGET trial as a plea for model-informed precision dosing of piperacillin/tazobactam in patients with sepsis	16
What language conveys distress and reassurance?	16
Another trial for the TARGET trial. Author’s reply	16