Intensive Care Medicine

Article	Citations
Coupled plasma filtration and adsorption for the treatment of septic shock	2148
Influenza and prophylactic antifungal therapy for aspergillosis: addressing some questions first	583
Double the risk of death and other ‘inconvenient truths’ about oliguria. Author's reply	279
Face-to-face courses: the environmental considerations for centralised vs local approaches using a free, open-access, online carbon cost calculator	237
When could airway plateau pressure above 30 cmH2O be acceptable in ARDS patients?	223
Potential role for interferon gamma in the treatment of recurrent ventilator-acquired pneumonia in patients with COVID-19: a hypothesis	178
Higher mortality in female versus male critically ill patients at comparable thresholds of mechanical power: necessity of normalization to functional lung size	170
Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study	157
Ten tips on fever	154
Anesthetic drugs for rapid sequence intubation: ketamine, but what dose?	146
Citrate anticoagulation for continuous renal replacement therapy	146
Using the helmet	130
Oxygen thresholds in critically ill patients: need for personalized targets	123
The legacy of the interprofessional family meeting	120
Diversity and inclusivity: the way to multidisciplinary intensive care medicine in Europe	113
Circular material flow in the intensive care unit—environmental effects and identification of hotspots	112
Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia	108
Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia	101
Long-term outcomes with haloperidol versus placebo in acutely admitted adult ICU patients with delirium	100
The REMDACTA trial: do interleukin receptor antagonists provide additional benefit in COVID-19?	100
Redefining the paradigm: incentivizing the peer review process for scientific advancement	98
Validation of pre-conditioning EASIX for prediction of sepsis after allogeneic stem cell transplantation	97
Helmet noninvasive support in hypoxemic respiratory failure	94
Full enteral nutrition should be avoided among patients with high vasopressor dose and low flow state	92
Use of stylet and airway management procedure in critically ill patients	86

Before AKI, renal microcirculation stress may be detected by urine biochemistry. Author’s reply	86
Chicken or the egg? Critical illness and mental health	85
Empirical antimicrobials in the intensive care unit	82
COVID-19-associated pulmonary aspergillosis (CAPA) might be associated with increased risk for pneumopleural fistula	78
Prehospital ventilation targets in severe traumatic brain injury	77
Effectiveness of blue light-emitting glasses for intensive care unit health care workers on night shifts during the COVID-19 pandemic	72
Where is the imperceptible difference?	72
The TARGET trial as a plea for model-informed precision dosing of piperacillin/tazobactam in patients with sepsis	71
No blood transfusion for my own anaemia—tit for tat?	71
The environmental impact of laboratory measurements in high-resource ICUs	68
Learning from our unit’s first exorcism	67
The Janus face of oxygen in traumatic brain injury	65
The relationship between treatment limitations and pressure on intensive care units in elderly patients	65
Bedside-available strategies to minimise P-SILI and VILI during ARDS	65
What should a “surviving severe ACLF campaign” look like?	64
Renal function in the ICU: always look both ways before initiating venous thromboprophylaxis	59
Complexity and unanswered questions in the pathophysiology of COVID-19 ARDS	58
Thirty years of career in Intensive Care Medicine	58
Decision-making process during limitation life-sustaining support meetings in French intensive care units	57
Is (1,3)-β-d-glucan useless to guide antifungal therapy in ICU?	57
Venous thromboembolism in critically ill adult patients with hematologic malignancy: a population-based cohort study	56
The cytokine adsorber Cytosorb® does not reduce ammonia concentrations in critically ill patients with liver failure	56
Decidual stromal cells for the treatment of severe COVID-19 ARDS	56
Immune-mediated thrombotic thrombocytopenic purpura: don’t miss the boat	55
Factors associated with successful liberation from continuous renal replacement therapy in children and young adults: analysis of the worldwide exploration of renal replacement outcomes collaborative	55
Transforming waste management in intensive care units: a path towards environmental sustainability and resource optimization	53
ICU-specific factors associated with venous thromboembolism and bleeding	52
Rapid syndromic multiplex PCR panels for the management of ventilator-associated lower respiratory tract infections: pondering important limitations. Author’s reply	51
The effectiveness of alkaline phosphatase in sepsis-associated acute kidney injury	50
One-year outcomes in acute respiratory distress syndrome survivors: COVID-19 versus seasonal influenza or pneumonia	50
Sometimes, less is just less…	49
Etomidate for endotracheal intubation in sepsis	49
Basic ultrasound skill for intensivists: future scope for expansion of the recommendations of the European Society of Intensive Care Medicine. Author's reply	49
Early prognostic value of non-invasive intracranial pressure methods in brain-injured patients	49
Attributable climate emissions: an important public- and patient-centered outcome for intensive care trials	48
Choice of priors: how much scepticism is appropriate?	48
The new global definition of ARDS loses one of the first games: a chromatic advice	46
Weaning strategy in patients at low-to-medium risk of extubation failure	46
Norepinephrine dose and concentration reporting: a closer look at the fine print	46
Noninvasive neuromonitoring in acute brain injured patients	45
Another trial for the TARGET trial. Author’s reply	45
COVID-19-associated autoimmunity as a feature of acute respiratory failure	45
Acute respiratory distress syndrome guidelines: oceans apart or rivers that merge?	45
Time course of physiological variables during inter-hospital helicopter transport of ventilated COVID-19 patients	45
What about permissive acidosis?	43
Fluid management in diabetic ketoacidosis: new tricks for old dogs?	42
Effect of proning and recruitment on physio-anatomical variables in COVID-19 pneumonia	42
Prognostication model for traumatic brain injury based on age and white matter diffusion metrics in MRI brain. Author’s reply	42
Characterising right ventricular dysfunction in acute respiratory distress syndrome due to COVID-19: which measurements are best?	42
Routine colonoscopy in patients with high risk of non-occlusive mesenteric ischemia	41

The choice of crystalloid type in the intensive care unit is likely more complex than expected: should doubt benefit the patient?	41
Fentanyl- and midazolam-induced coma each influence days of mechanical ventilation and 28-day mortality	40
A double plea for dyspnea as the next great cause of all ICU professions and for caution about the dyspnea-breathlessness equivalence	40
Ableism in the intensive care unit	40
Sequencing interventions in ARDS: the critical role of timing and order in standardized management	40
Pick your prior: scepticism about sceptical prior beliefs	39
Development and validation of early prediction models for new-onset functional impairment at hospital discharge of ICU admission	39
Ultrasound-guided catheterization and infectious risk in obese ICU patients	39
Greenery and outdoor facilities to improve the wellbeing of critically ill patients, their families and caregivers: things to consider	39
The AKI care bundle: all bundle components are created equal—are they?	38
Immune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial	37
De senectute and the art of medicine: how old is too old for ECMO in cardiogenic shock?	36
Nicotine patches in patients on mechanical ventilation for severe COVID-19: a randomized, double-blind, placebo-controlled, multicentre trial	36
Microcirculation as a guide for therapy: do not condemn an innocent without a fair trial	36
Racial and ethnic minority participants in clinical trials of acute respiratory distress syndrome	35
Size does matter. Sustainable choice of intravenous bags	33
Staying optimistic in the face of war	33
All that glitters is not gold: an unusual presentation of S. aureus sepsis during ECMO	33
Personalized medicine in COVID-19	33
Understanding purpura fulminans in adult patients	32
Ten myths about albumin: do not forget the endothelium	32
Decontamination regimens: do not forget half of the protocol. Author's reply	32
The pathophysiology of anaphylactic shock captured on computed tomography images	32
Intracranial pressure monitoring devices compatibility with magnetic resonance imaging	31
Pitfalls in the use of microcirculation as a resuscitation goal	31
Severe hemophagocytic lymphohistiocytosis in kidney transplant recipient: the etiology is on the tip of the tongue!	31
Acute respiratory failure from an obstructive fibrinous tracheal pseudomembrane	31
Management of supraventricular arrhythmias in the intensive care unit: a step in the right direction	31
Evolution of purpura fulminans	30
Close collaboration between pathologists and intensivists to understand (not just) coronavirus disease	29
Obituary and tribute to Professor J. Randall Curtis (Randy)	29
The certainty of parental love vs. the uncertainty of a “best” decision	29
What language conveys distress and reassurance?	28
Terlipressin use in hepatorenal syndrome-acute kidney injury in cirrhosis	28
Cardiac manifestations in critically ill patients with COVID-19: do we really know what hit us?	27
Basic ultrasound skill for intensivists: future scope for expansion of the recommendations of the European Society of Intensive Care Medicine	27
Workplace equity for clinicians with a disability: why it matters for all	26
Severe Pneumocystis jirovecii pneumonia: time to reassess our practices	26
18F-fluorodeoxyglucose positron emission tomography/computed tomography differentiates between pneumonia and atelectasis in a mechanically ventilated patient	26
Corticosteroids in H1N1, non-viral, and COVID-19 ARDS	26
The limitations of evidence-based medicine compel the practice of personalized medicine	25
Treating necrotizing skin and soft-tissue infections	25
Thrombolysis before venoarterial ECMO for high-risk pulmonary embolism: a retrospective cohort study	25
Post-intensive care unit follow-up: don’t stop it now!	25
Critical insights into venoarterial extracorporeal membrane oxygenation outcomes in immunocompromised patients: addressing uncertainties in cause of death and treatment strategies	25
Probiotic therapy in critical illness: does it hold water?	24
Tackling sepsis-associated acute kidney injury using routinely collected data	24
The effect of vasopressin and hydrocortisone on cytokine trajectories	24
Harlequin syndrome after surgery for aortic dissection	24
Hope will never be silent: standing tall with the LGBTQ + community	24
Beyond failure or success: reflections on the ethical justifications for time-limited trial of intensive care	24
Federated learning: a step in the right direction to improve data equity	24
Hypnotic suggestions of safety improve well-being in non-invasively ventilated patients in the intensive care unit	24
High prevalence of acute stress disorder and persisting symptoms in ICU survivors after COVID-19	23
Virtual reality in intensive care	23
Ten tips to manage severe acute pancreatitis in an intensive care unit	23
The moral problems with time-limited trials at the end-of-life, especially when clinicians and patients have different goals	23
Organ donation after circulatory death: please avoid undue haste!	22
The effects of pantoprazole vs. placebo on 1-year outcomes, resource use and employment status in ICU patients at risk for gastrointestinal bleeding: a secondary analysis of the SUP-ICU trial	22
Critical care ultrasound goal-directed versus early goal-directed therapy in septic shock	22
Dose of norepinephrine: the devil is in the details	22
Thromboprophylaxis in critical care	21
What's new with glucocorticoids in severe community-acquired pneumonia?	21
Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis	21
High-risk pulmonary embolism in the intensive care unit	21
Falsifiability in medicine: what clinicians can learn from Karl Popper	21
Obesity and risk of catheter-related infections in the ICU. A post hoc analysis of four large randomized controlled trials	21
Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial	21
Optimal oxygen and mean arterial blood pressure targets after cardiac arrest	21
The role of policy and law in shaping the ethics and quality of end-of-life care in intensive care	21
Real-time 4D transesophageal echocardiography in the evaluation of cardioaortic embolism: the value of completing a comprehensive protocol	21
Trash in/trash out? Using routinely collected clinical data for data science in the ICU: Con	21
Considerations for β-lactam antimicrobial continuous infusion. Authors’ reply to Massart et al. and Marzaroli et al.	21
Behavioural artificial intelligence technology for COVID-19 intensivist triage decisions: making the implicit explicit	20
Lung recruitment	20
Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis	20
Safety and efficacy of artesunate treatment in severely injured patients with traumatic hemorrhage. The TOP-ART randomized clinical trial	20
Pharyngeal abscess: a rare complication of repeated nasopharyngeal swabs	20
If not now, when? A clinical perspective on the unprecedented challenges facing ICUs during the COVID-19 pandemic	20
Status epilepticus in the ICU	20

Dichotomy between ventilator-associated pneumonia/-tracheobronchitis: did you ask the lung its opinion?	20
Bedside ultrasound monitoring of prone position induced lung inflation	19
Measuring patient’s effort on the ventilator	19
Navigating complex interventions in post-ICU care: insights from a randomized clinical trial of post-intensive care multidisciplinary consultations	19
Artificially intelligent reflection? Smoke and mirrors and a tale of two perspectives	19
Federated data access and federated learning: improved data sharing, AI model development, and learning in intensive care	19
High-flow oxygen during spontaneous breathing trial for patients at high risk of weaning failure	19
Determining the optimal number of lung ultrasound zones to monitor COVID-19 patients: can we keep it ultra-short and ultra-simple?	18
The 5-year pre- and post-hospitalization treated prevalence of mental disorders and psychotropic medication use in critically ill patients: a Canadian population-based study	18
Tocilizumab in COVID-19: a meta-analysis, trial sequential analysis, and meta-regression of randomized-controlled trials	18
Driving pressure: applying the concept at the bedside	18
Ventilator induced lung injury: a case for a larger umbrella?	18
Age and associated outcomes among patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory failure: analysis of the Extracorporeal Life Support Organization registry	18
No clinically relevant removal of meropenem by cytokine adsorber CytoSorb® in critically ill patients with sepsis or septic shock	17
Central venous catheter-related infection: does insertion site still matter? A French multicentric cohort study	17
Treating acute encephalitis	17
Fluid responsiveness in acute respiratory distress syndrome patients: a post hoc analysis of the HEMOPRED study	17
Sex-, gender-, and diversity-based analysis of the Intensive Care Medicine Journal’s most-cited articles of 2023	17
Paediatric intensive care challenges caused by indirect effects of the COVID-19 pandemic	17
Broad use of processed EEG: ready for prime time yet?	17
Early endothelial injury in cardiogenic shock patients on venoarterial ECMO	17
Quantifying benefit and harm of extracorporeal life support in cardiogenic shock complicating acute myocardial infarction	17
How environmental impact is considered in economic evaluations of critical care: a scoping review	17
Introducing an external team for ICU family communication during the pandemic: not without risks	17
Navigating the ventilator in acute brain injury: a forceful call for clarity and caution	17
Effect of the 1-h bundle on mortality in patients with suspected sepsis in the emergency department: faster is better for the sicker ones! Author’s reply	17
No ventilation, no ARDS: insights from four-dimensional computed tomography as dynamic imaging	17
Addressing key considerations in the use of 20% human albumin for fluid resuscitation in cardiac surgery. Author’s reply	17
End-of-life care awareness in a low–middle-income country: a plea for improvement	17
Post-hospital recovery trajectories of family members of critically ill COVID-19 survivors: an international qualitative investigation	17
Challenging management dogma where evidence is non-existent, weak, or outdated: part II	16
The use of echocardiography in the management of shock in critical care: a prospective, multi-centre, observational study	16
Long-term outcomes of critically ill patients with hematological malignancies: what is the impact of the coronavirus disease 2019 pandemic?	16
Should we abandon the CAM-ICU and practice “humanizing care” for all patients?	16
Subphenotypes in critical illness: a priori biological rationale is key	16
European Society of Intensive Care Medicine guidelines on end of life and palliative care in the intensive care unit	16
Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study	16
Understanding, assessing and treating immune, endothelial and haemostasis dysfunctions in bacterial sepsis	15
Use of vasopressors and inotropes in ECMO	15
Comparison of radiographic pneumothorax and pneumomediastinum in COVID-19 vs. non-COVID-19 acute respiratory distress syndrome	15
Monitoring cerebral oxygenation in acute brain-injured patients	15
Major adverse kidney events as an endpoint in acute kidney injury trials: is it time for a RE-MAKE?	15
“It’s all about setting the stage.” The nurse facilitator trial: perceived outcomes and implementation issues. A qualitative study among ICU clinicians and nurse facilitators	15
Association of vancomycin plus piperacillin–tazobactam with early changes in creatinine versus cystatin C in critically ill adults: a prospective cohort study	15
Long-term outcomes in nutrition trials: after all, this is what our patients are looking for!!	15
Challenges in optimizing the treatment of Pneumocystis pneumonia in the intensive care unit. Author’s reply	15
Moving from bytes to bedside: a systematic review on the use of artificial intelligence in the intensive care unit	15
Model-informed precision dosing of beta-lactam antibiotics and ciprofloxacin in critically ill patients: a multicentre randomised clinical trial	15
Intra-cycle power: is the flow profile a neglected component of lung protection?	14
Visitation policies in the ICU and the importance of family presence at the bedside	14
Electrical impedance tomography-guided positive end-expiratory pressure titration in ARDS: a systematic review and meta-analysis	14
SHAP model explainability in ECMO–PAL mortality prediction: a critical analysis	14
Liver transplantation for patients with severe acute on chronic liver failure: it is time to change paradigms	14
Resistance to unfractionated heparin in the ICU: evaluation and management options	14
Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions	14
Exposure to ambient air pollutants and acute respiratory distress syndrome risk in sepsis	14
Cardiac injury in COVID-19	14
ROX index to predict CPAP outcome in hypoxemic respiratory failure due to COVID-19	14
Back to the future: ARDS guidelines, evidence, and opinions	14
Lung-protective sedation: moving toward a new paradigm of precision sedation	14
Management of chimeric antigen receptor T (CAR-T) cell-associated toxicities	14
Spontaneous pulmonary-twist secondary to Legionnaire’s disease	14
The association of the COVID-19 pandemic and short-term outcomes of non-COVID-19 critically ill patients: an observational cohort study in Brazilian ICUs	13
Hospital factors that influence ICU admission decision-making: a qualitative study of eight hospitals	13
Impact of BMI on outcomes in respiratory ECMO: an ELSO registry study	13
Daily point-of-care ultrasound-assessment of central venous catheter-related thrombosis in critically ill patients: a prospective multicenter study	13
Plasma exchange in the intensive care unit: a narrative review	13
Frailty in intensive care medicine must be measured, interpreted and taken into account!	13
How to improve intubation in the intensive care unit. Update on knowledge and devices	13
Taskforce report on the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis	13
Precision management of acute kidney injury in the intensive care unit: current state of the art	13
Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets	13
Machine learning to predict poor school performance in paediatric survivors of intensive care: a population-based cohort study	13
Psychological distress and morbidity of family members experiencing virtual visiting in intensive care during COVID-19: an observational cohort study	13
High-level burnout in physicians and nurses working in adult ICUs: a systematic review and meta-analysis	13
Excess mortality among non-COVID-19 surgical patients attributable to the exposure of French intensive and intermediate care units to the pandemic	13
Interferon gamma-1b for the prevention of hospital-acquired pneumonia in critically ill patients: a phase 2, placebo-controlled randomized clinical trial	13
Correction to: Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial	12
Correction to: Noninvasive respiratory support in intensive care medicine	12
Correction: Partition of respiratory mechanics in patients with acute respiratory distress syndrome and association with outcome: a multicentre clinical study	12
Dyspnoea in acutely ill mechanically ventilated adult patients: an ERS/ESICM statement	12
Phrenic nerve stimulation to protect the diaphragm, lung, and brain during mechanical ventilation	12
Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study	12
Correction: Feasibility of conservative fluid administration and deresuscitation compared with usual care in critical illness: the Role of Active Deresuscitation Correction: After Resuscitation-2 (RAD	12
Correction: Intracranial pressure: current perspectives on physiology and monitoring	12
Correction: The role of centre and country factors on process and outcome indicators in critically ill patients with hospital-acquired bloodstream infections	12
Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury	12
Mental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort study	12
Variation in intensive care unit beds capacity in China from 2007 to 2021	12
Correction: Rapid multiplex PCR panels for the management of ventilator-associated pneumonia: pondering strengths and weaknesses	12
Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis	12
Dexmedetomidine vs other sedatives in critically ill mechanically ventilated adults: a systematic review and meta-analysis of randomized trials	12
Early physiologic changes after awake prone positioning predict clinical outcomes in patients with acute hypoxemic respiratory failure	11
Personalized oxygen targets are needed for extracorporeal membrane oxygenation	11
Fludrocortisone dose–response relationship in septic shock: a randomised phase II trial	11