Intensive Care Medicine

Article	Citations
Variation in intensive care unit beds capacity in China from 2007 to 2021	556
Obituary and tribute to Professor J. Randall Curtis (Randy)	200
The effects of pantoprazole vs. placebo on 1-year outcomes, resource use and employment status in ICU patients at risk for gastrointestinal bleeding: a secondary analysis of the SUP-ICU trial	176
Effect of proning and recruitment on physio-anatomical variables in COVID-19 pneumonia	174
Time course of physiological variables during inter-hospital helicopter transport of ventilated COVID-19 patients	171
Basic ultrasound skill for intensivists: future scope for expansion of the recommendations of the European Society of Intensive Care Medicine	156
Full enteral nutrition should be avoided among patients with high vasopressor dose and low flow state	147
Correction: Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis	140
Weaning strategy in patients at low-to-medium risk of extubation failure	138
Workplace equity for clinicians with a disability: why it matters for all	137
Major adverse kidney events as an endpoint in acute kidney injury trials: is it time for a RE-MAKE?	135
Personalized oxygen targets are needed for extracorporeal membrane oxygenation	127
Preventing stress ulcer bleeding	123
No ventilation, no ARDS: insights from four-dimensional computed tomography as dynamic imaging	109
Quantifying benefit and harm of extracorporeal life support in cardiogenic shock complicating acute myocardial infarction	106
Close collaboration between pathologists and intensivists to understand (not just) coronavirus disease	105
The certainty of parental love vs. the uncertainty of a “best” decision	102
Optimal oxygen and mean arterial blood pressure targets after cardiac arrest	98
Pitfalls in the use of microcirculation as a resuscitation goal	97
Correction to: Noninvasive respiratory support in intensive care medicine	95
Norepinephrine dose and concentration reporting: a closer look at the fine print	94
Staircase strategy, tier-three therapies, and effects on outcome in traumatic brain injured patients: the Triple-T TBI study	91
Lung-protective sedation: moving toward a new paradigm of precision sedation	86
Dose of norepinephrine: the devil is in the details	85
Status epilepticus in the ICU	84

Measuring patient’s effort on the ventilator	81
Delivering optimal renal replacement therapy to critically ill patients with acute kidney injury	80
Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized controlled trial	78
Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study	78
Using the helmet	77
Mental health sequelae in survivors of cardiogenic shock complicating myocardial infarction. A population-based cohort study	76
Persistent signs of poisoning after massive drug ingestion: move the ultrasound probe to the stomach	76
Comparing intravascular and surface cooling methods: a critical look at outcomes for out-of-hospital cardiac arrest patients—author's reply	74
Beyond inflammation: the role of metabolic dysregulation in sepsis diagnosis and treatment	72
Hemodynamic and neurological presentations of invasive meningococcal disease in adults: a nationwide study across 100+ French ICUs	72
Serum sickness: a mimic of septic shock	71
A double plea for dyspnea as the next great cause of all ICU professions and for caution about the dyspnea-breathlessness equivalence	69
Severe Pneumocystis jirovecii pneumonia: time to reassess our practices	68
Sequencing interventions in ARDS: the critical role of timing and order in standardized management	68
Greenery and outdoor facilities to improve the wellbeing of critically ill patients, their families and caregivers: things to consider	65
18F-fluorodeoxyglucose positron emission tomography/computed tomography differentiates between pneumonia and atelectasis in a mechanically ventilated patient	62
Correction: Expanding the role of PoCUS in tailoring diuretic strategies for congestion management in critical care	62
Anesthetic drugs for rapid sequence intubation: ketamine, but what dose?	61
Nicotine patches in patients on mechanical ventilation for severe COVID-19: a randomized, double-blind, placebo-controlled, multicentre trial	60
Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia	58
Frailty in intensive care medicine must be measured, interpreted and taken into account!	58
Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions	58
SHAP model explainability in ECMO–PAL mortality prediction: a critical analysis	56
ICU venous thromboembolism prophylaxis: revisiting external validity, vulnerable subgroups, and diagnostic standards, with future directions. Authors' reply	56
Age and associated outcomes among patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory failure: analysis of the Extracorporeal Life Support Organization registry	54
Left ventricular diastolic dysfunction is prevalent but not associated with mortality in patients with septic shock	53
Exposure to ambient air pollutants and acute respiratory distress syndrome risk in sepsis	53
Less is more. Atmospheric and environmental stakes - sedate with care	52
B-ICONIC vs. Reality: The Feasibility Gap in Neuro-Ultrasound Recommendations and Achievability. Authors’ reply	52
“Fake” or real hypoxia?: A brainy dilemma	51
Should we move beyond the concept of fluid responsiveness?	51
Ten myths about Albumin: don’t forget the endothelium. Author’s reply	50
Relationship of multidrug-resistant bacterial colonization and immune status of patients in the ICU	49
Dichotomy between ventilator associated-pneumonia/tracheobronchitis: did you ask the lung its opinion? Author's reply	49
Role of PEEP on the prognostic performance of the ROX index in hypoxemic respiratory failure due to COVID-19: any further gain in outcome prediction?	49
NeuroWatch in acute respiratory distress syndrome: time to tune strategies	48
Central venous pressure not appropriate to guide volume administration in patients with high-risk pulmonary embolism	48
The role of pleural pressure and airway closure during mechanical ventilation. Author's reply	48
Rapid temperature increases under isoflurane sedation	48
Correction: Determinants of fluid use and the association between volume of fluid used and effect of balanced solutions on mortality in critically ill patients: a secondary analysis of the BaSICS tria	48
Retraction Note: Influence of nimodipine and nifedipine on intrapulmonary shunting – a comparison to other vasoactive drugs	46
A call to measure family presence in the adult intensive care unit	46
Introduction to an intensive care recycling program	46
Bone marrow necrosis induced by massive Staphylococcus aureus infiltration	46
Towards evidence-based staffing: the promise and pitfalls of patient-to-intensivist ratios	45
Visco-elastic testing in traumatic bleeding	45
Ten myths about albumin	44
Management of diabetic ketoacidosis	44
How can assessing hemodynamics help to assess volume status?	43
The challenge of pharmacological thromboprophylaxis in ICU patients: anti-FXa activity does not constitute a simple solution	43

Humanizing Delirium Care	42
Frailty is crucial in FORECASTing outcomes in critical care	42
What’s new in intensive care: disease tolerance	42
Head up, face down—a practical framework for proning brain-injured patients with ARDS	41
Identifying distinct clusters of ICU survivors by integrating demographic, pre-admission quality of life, and clinical data: a large prospective cohort study	41
Septic shock secondary to a rat-bite fever	41
A common longitudinal intensive care unit data format (CLIF) for critical illness research	41
Sepsis subphenotypes, theragnostics and personalized sepsis care	41
Effects of small volume resuscitation with hypertonic saline on body water distribution in ICU patients after cardiac surgery	41
High versus low positive end-expiratory pressure during noninvasive ventilation for hypoxemic respiratory failure: balancing efficacy and lung protection—author’s reply	40
Correction: Association of hospital and intensive care unit occupancy and non-admission to the intensive care unit decisions: a retrospective cohort study	40
The role of pleural pressure on fluid dynamics and responsiveness	40
Left atrial reservoir strain: an essential tool for evaluating left ventricular diastolic dysfunction in 2025	40
Position paper on the physiology and nomenclature of dual circulation during venoarterial ECMO in adults	40
Can the terms “low resource setting” and “low-income country” be used interchangeably in the context of intensive care medicine?	39
Reevaluating definitions and modifiable factors in persistent severe acute kidney injury	39
Kidney replacement therapy in critically ill obese patients: an urgent call for precision and evidence-based practice!	38
Awareness of dying: adjustments in family relationships at the end of life	38
Penicillin allergy assessment and testing: worth the risk in critically ill patients	38
Correspondence on "Using toxidromes in the ICU"	38
Double sequential external defibrillation for refractory ventricular fibrillation	38
Defining basic (lung) ultrasound skills; not so basic after all? Author’s reply	38
Renal replacement therapy initiation strategies in comatose patients with severe acute kidney injury: a secondary analysis of a multicenter randomized controlled trial	37
Head-to-toe bedside ultrasound for adult patients on extracorporeal membrane oxygenation	36
Ten reasons for the presence of pharmacy professionals in the intensive care unit	35
Drugs for advanced life support	35
Monocyte HLA-DR expression in septic shock patients: insights from a 20-year real-world cohort of 1023 cases	35
Anesthetic drugs for rapid sequence intubation: ketamine, but what dose? Author’s reply	35
Selective digestive decontamination- Not sure	35
Undocumented migrants in French intensive care units in 2011–2018: retrospective nationwide study	35
Intensive Care admission aiming at organ donation as a duty of the intensivist: every organ, every time	34
What really matters with thrombocytopenia: absolute value, timing, etiology or management? Author's reply	34
Correction to: Palliative care interventions in intensive care unit patients	34
Effect of albumin bolus therapy on vasopressor requirement after cardiac surgery	33
Caring for the dying patient in ICU	33
Multiple intracardiac thrombi in a patient with extracorporeal membrane oxygenation	33
Long-term survival comparison of patients admitted to the intensive care unit following in-hospital cardiac arrest in perioperative and ward settings. A multicentre retrospective cohort study	32
Correction: ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia	32
Consumptive coagulopathy: how low-dose unfractionated heparin can prevent bleeding complications during extracorporeal life support	32
Building a better machine learning model of extubation for neurocritical care patients. Author’s reply	32
Achievement of therapeutic antibiotic exposures using Bayesian dosing software in critically unwell children and adults with sepsis	32
Melatonin for prevention of delirium in patients receiving mechanical ventilation in the intensive care unit: a multiarm multistage adaptive randomized controlled clinical trial (DEMEL)	31
Long-term outcomes of intensive care unit delirium	31
Ten tips on sepsis-induced thrombocytopenia	31
Treatment of positive catheter tip culture without bloodstream infections in critically ill patients. A case-cohort study from the OUTCOMEREA network	31
Lung and diaphragm protective ventilation guided by the esophageal pressure	31
Beyond the numbers: do nomograms capture the complexity of RRT dosing? Author’s reply	31
Noninvasive ventilation on reintubation in patients with obesity and hypoxemic respiratory failure following abdominal surgery: a post hoc analysis of a randomized clinical trial	30
ECMO PAL: using deep neural networks for survival prediction in venoarterial extracorporeal membrane oxygenation	30
Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome	30
Optimising aerosolized therapies in critically ill patients	30
Targeting inflammation in traumatic injury: entering a new era	30
Bronchoscopy for diagnosis of ventilator-associated pneumonia	29
Tracheal intubation in critically ill adults with a physiologically difficult airway. An international Delphi study	29
ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia	29
Microcirculation information in clinical decision making: Rome wasn't built in a day	29
Managing blood glucose control in the intensive care unit	28
Plasma exchange in septic shock: are we ready for prime time? PRO	28
Integrating multidisciplinary expertise in postoperative noninvasive ventilation management. Authors’ reply	28
Bronchoscopic examination of an invasive aspergillosis in acute myeloid leukemia	28
Reusable versus single-use ICU equipment: what’s the environmental footprint?	28
Effect of albumin bolus therapy on vasopressor requirement after cardiac surgery? Author’s reply	28
On acid-base bilingualism	28
De-adoption of chlorhexidine oral care and ICU mortality. Authors’ reply	28
Critical insights into venoarterial extracorporeal membrane oxygenation outcomes in immunocompromised patients: addressing uncertainties in cause of death and treatment strategies. Author’s reply	28
Terlipressin use in HRS-AKI and respiratory failure	28
Subphenotypes in critical illness: a priori biological rationale is key. Author’s reply	28
Delirium in ICU and Macbeth’s dagger: author’s reply	27
Understanding buffering of metabolic acidosis in critical illness	27
What intensivists need to know about cytomegalovirus infection in immunocompromised ICU patients	27
Hemoadsorption in septic shock – PRO	27
Bridging the gap: implementing ESICM end-of-life care guidelines in resource-limited settings	27
Caring for frail patients in the ICU: a multidimensional approach	26
AI in neurocritical care: what to expect	26
Unlocking consciousness through right median nerve stimulation. Has a potential cure arrived at our doorstep?	26
Acute kidney injury	26
Driving pressure as a target for lung protective strategies: from ARDS critically-ill patients to the operating room—Lessons from the IMPROVE-2 Trial	26
Prognostic value of global deep white matter DTI metrics for 1-year outcome prediction in ICU traumatic brain injury patients: an MRI-COMA and CENTER-TBI combined study	26
How to approach a patient hospitalized for pneumonia who is not responding to treatment?	26
Antibiotic therapy for severe bacterial infections	26

Open-source clinical classifiers for ARDS: democratizing precision or diluting biology?	26
Accuracy of continuous glucose monitoring systems in intensive care unit patients: a scoping review	26
Retraction Note: Phosphodiesterase-inhibitors enoximone and piroximone in cardiac surgery: influence on platelet count and function	25
Ecological effects of selective oral decontamination on multidrug-resistance bacteria acquired in the intensive care unit: a case–control study over 5 years	25
Invasive Fungal Diseases in Adult Patients in Intensive Care Unit (FUNDICU): 2024 consensus definitions from ESGCIP, EFISG, ESICM, ECMM, MSGERC, ISAC, and ISHAM	25
Machines that help machines to help patients: optimising antimicrobial dosing in patients receiving extracorporeal membrane oxygenation and renal replacement therapy using dosing software	25
High and intermediate risk pulmonary embolism in the ICU	25
Hyperoxia and traumatic brain injury: time to stop cooking the books?	24
Obituary and tribute to Professor Tobias Welte	24
Massive gaseous embolism during cardiopulmonary resuscitation for massive hemoptysis in a COVID-19-associated pulmonary aspergillosis	24
Come hell or high water: climate change through the lens of neurocritical care	24
We are proud of you Jamie	24
Analgesia as part of the orotracheal intubation induction sequence. Author's reply	24
Human albumin solution for on-pump cardiac surgery: benefit or burden? Author’s reply	24
Coronavirus disease 2019	24
Delirium Related to Sedation: Prevention Strategies and Patient Perspectives	23
Sex representation within intensive care trials in Australia and New Zealand	23
Characteristics of co-infection and secondary infection amongst critically ill COVID-19 patients in the first two waves of the pandemic	23
Correction to: Survival benefit of extracorporeal membrane oxygenation in severe COVID-19: a multi-centre-matched cohort study	23
Clinical governance in intensive care medicine	23
C-reactive protein rise in response to macronutrient deficit early in critical illness: sign of inflammation or mediator of infection prevention and recovery	23
My advice to the NEXT generation	23
Deploying AI in the ICU: learning from successes and failures	23
Preventing acute kidney injury and its longer-term impact in the critically ill	23
Equity in patient care in the intensive care unit	23
Early ICU mobilisation predicting functional impairment at hospital discharge. Author's reply	23
Confusion regarding the use of Natural Language Processing in ICU delirium assessment. Author’s reply	23
Contemporary management of major haemorrhage in critical care	22
The dawn of target trials in intensive care: time to move beyond association is not causation	22
Absence of candidemia in critically ill patients with COVID-19 receiving selective digestive decontamination	22
Ceremonial purification: which rite is right in liver failure?	22
Using ultrasound in ICU	22
Incidence and risk factors of mental illness among the spouses of patients with sepsis: a population-based cohort study	22
Neuromonitoring for prognostication under ECMO	22
Heterogeneity in a meta-analysis: randomized controlled trials versus observational studies	22
Monitoring cardiac output	22
Ketamine for emergency endotracheal intubation: insights into post-induction hemodynamic instability	22
How to optimize extubation?	21
Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial	21
Time-limited trial of intensive care is more than merely life sustaining	21
Central venous pressure (CVP)	21
Prevention of upper gastrointestinal bleeding in critical illness	21
Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial	21
Correction: Thrombocytopenia and platelet transfusions in ICU patients: an international inception cohort study (PLOT-ICU)	20
Challenges for a broad international implementation of the current severe community-acquired pneumonia guidelines	20
Air pollutant exposure and mortality risk of critically ill patients	20
War, from the inside	20
Respective roles of hypercapnia and acidosis in acute distress respiratory syndrome	20
Unraveling the enigma of genetics and phenotypes in ARDS	19
During the storm	19
Brave enough	19
Gymnopédie: music in the ICU	19
Correction: Variation in intensive care unit beds capacity in China from 2007 to 2021	19
Driving pressure: pitfalls of methods that do not use esophageal pressure measurement	19
Correction: Effect modification in a clinical trial should be assessed through interaction terms, not prognostic modelling	19
Human albumin solution for on-pump cardiac surgery: benefit or burden?	18
Correction: Influence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2: the multicentre, observational RECOVIDS study	18
Optimizing ICU antifungal therapy: overcoming pharmacokinetic limitations with combination strategies—author's reply	18
Validation of the “invasive pulmonary aspergillosis in immunocompromised patients with acute respiratory failure score” (IPA-GRRR-OH score)	18
The next big epidemic? Device shutdowns	18
The relationship of malnutrition, frailty, and sarcopenia in critical care	18
Retraction Note: The new phosphodiesterase inhibitor enoximone in patients following cardiac surgery – pharmacokinetics and influence on parameters of coagulation	18
To mobilise or not to mobilise: is that the right question?	18
The role of inferior vena cava in predicting fluid responsiveness	18
Shorter might not always be better: the case for longer antibiotic therapy for Pseudomonas aeruginosa pneumonia	18
Bidirectional ventricular tachycardia, a very rare and severe complication of digoxin poisoning	18
Retraction Note: Right ventricular function and cardiac surgery	18
Sex and gender differences in intensive care medicine	17
Correction: Direct assessment of microcirculation in shock: a randomized-controlled multicenter study	17
Post-intensive care syndrome is a potential consequence of critical care: can intensivists afford to look away?	17
REMAP-CAP corticosteroids: yet, another swing of the pendulum?	17
Increased risk of central line-associated bloodstream infection in COVID-19 patients associated with dexamethasone but not with interleukin antagonists	17
Author Correction: Hemoadsorption in septic shock—CON	17
Recommendations for clinical trial design in acute kidney injury from the 31st acute disease quality initiative consensus conference. A consensus statement	17
Norepinephrine pharmacolexicology: a chronological review of dose reporting and the implications of salt formulations	17
Shortening antibiotic therapy duration for hospital-acquired bloodstream infections in critically ill patients: a causal inference model from the international EUROBACT-2 database	17
Association between driving pressure and mortality may depend on timing since onset of acute respiratory distress syndrome	17
When ‘Early’ isn’t early: time to rethink the timing of mobilization in the ICU	17
Persistent severe AKI is bad—where to go now?	17
Correction: ESICM consensus-based recommendations for the management of very old patients in intensive care	17
Using diuretic therapy in the critically ill patient	17
Towards model-informed precision dosing of piperacillin: multicenter systematic external evaluation of pharmacokinetic models in critically ill adults with a focus on Bayesian forecasting	17
Hypervirulent Klebsiella pneumoniae: watch the eyes	17
Post-sepsis recovery: perspectives on measuring what matters. Author's reply	17
The forgotten relevance of central venous pressure monitoring	16
Onco-nephrology: what the intensivist needs to know	16
Intensive care management of acute-on-chronic liver failure	16
Clustering analysis of geriatric and acute characteristics in a cohort of very old patients on admission to ICU	16
Effect of aggressive vs conservative screening and confirmatory test on time to extubation among patients at low or intermediate risk: a randomized clinical trial	16
Retraction Note: The effects of pentoxifylline on circulating adhesion molecules in critically ill patients with acute renal failure treated by continuous veno-venous hemofiltration	16
Pressure control plus spontaneous ventilation versus volume assist-control ventilation in acute respiratory distress syndrome. A randomised clinical trial	16
The prediction of fluid responsiveness	16
The paradox of post-intensive care unit physical therapy	16
Challenges in optimizing the treatment of Pneumocystis pneumonia in the intensive care unit. Author’s reply	15
Venous thromboembolism in critically ill adult patients with hematologic malignancy: a population-based cohort study	15