Lung

Article	Citations
Lung Cancer in Never Smokers: Delving into Epidemiology, Genomic and Immune Landscape, Prognosis, Treatment, and Screening	111
Roles of Pyruvate Kinase M2 in Pulmonary Diseases: What Do We Know So Far?	70
Genetic Testing Goes Beyond Imaging and Histological Evaluation in Pleuroparenchymal Fibroelastosis	53
Hyperresponsiveness to Extracellular Acidification-Mediated Contraction in Isolated Bronchial Smooth Muscles of Murine Experimental Asthma	44
Diaphragm Ultrasonography: Reference Values and Influencing Factors for Thickness, Thickening Fraction, and Excursion in the Seated Position	42
Type 2 Biomarkers and Bronchiectasis	40
Serum Free Fatty Acid Concentration Predicts ARDS after Off-Pump CABG: A Prospective Observational Study	40
Neutralization of CX3CL1 Attenuates TGF-β-Induced Fibroblast Differentiation Through NF-κB Activation and Mitochondrial Dysfunction in Airway Fibrosis	39
Lung Tissue Compliance Interacts with Smooth Muscle and Drives Hyperresponsiveness in Mice with Experimental Asthma	35
Cmpk2 Protects Against Acute Lung Injury in Mice	35
Lung Microbiome as a Treatable Trait in Chronic Respiratory Disorders	35
Prognostic Impact of Cancer Inflammation Prognostic Index for Non-small Cell Lung Cancer	33
Illuminating Airway Nerve Structure and Function in Chronic Cough	30
Factors Associated with Corticosteroid Adherence in Sarcoidosis	29
Associations of the Serum KL-6 with Severity and Prognosis in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease	28
LUNG Year in Review: 2024	28
Impact of Functional Status at the Time of Transplant on Short-Term Pediatric Lung Transplant Outcomes in the USA	26
First Exploration of the Altered Microbial Gut–Lung Axis in the Pathogenesis of Human Refractory Chronic Cough	26
Pseudomonas aeruginosa Infection and Inflammation in Cystic Fibrosis: A Pilot Study With Lung Explants and a Novel Histopathology Scoring System	25
Outcomes of Concomitant Cardiac Surgical Procedures Performed During Pediatric Lung Transplantation in the United States	24
Pathophysiological Changes in Rhesus Monkeys with Paraquat-Induced Pulmonary Fibrosis	24
Exhaled Breath Analysis Using a Novel Electronic Nose for Different Respiratory Disease Entities	23
Burden of Disease Associated with Refractory and Unexplained Chronic Cough in Canada: Results from a National Survey	22
Thoracic Ultrasound in COVID-19: Use of Lung and Diaphragm Ultrasound in Evaluating Dyspnea in Survivors of Acute Respiratory Distress Syndrome from COVID-19 Pneumonia in a Post-ICU Clinic	22
Narrowing the Differential Diagnosis of Cystic Lesions in Smokers with Expiratory CT Acquisition Using the Cyst-Airway Communication Hypothesis	22

Role of Slc7a11 in Bleomycin-Induced Lung Injury	21
Percent Predicted vs. Absolute Six-Minute Walk Distance as Predictors of Lung Transplant-Free Survival in Fibrosing Interstitial Lung Diseases	21
Authors’ Reply to Letter to the Editor Regarding the Article “Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: a Two-Sample Mendelian Randomization Study”	20
Collagen-V and K-α-1 Tubulin Antibodies as Potential Markers of Unsuspected GERD-Related Lung Damage: Insights from a Cross-Sectional Analysis	19
Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: A Two-Sample Mendelian Randomization Study	19
The Association Between Insulin Use and Asthma: An Epidemiological Observational Analysis and Mendelian Randomization Study	18
Lower Oxygen Tension and Intracranial Hemorrhage in Veno-venous Extracorporeal Membrane Oxygenation	18
Prophylactic Inhaled Antibiotics for Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis of Incidence and Mortality Outcomes	18
Real-Life Response to Biologics in Severe Asthma with Nasal Polyposis: Insights from the Belgian Severe Asthma Registry	18
Role of Peripheral Blood Markers for Detecting Response and Predicting Prognosis in Patients with Non-small-cell Lung Cancer Undergoing Neoadjuvant Therapy and Surgery	17
MMP19 Variants in Familial and Sporadic Idiopathic Pulmonary Fibrosis	17
Current Applications of Artificial Intelligence in Sarcoidosis	16
Impact of Multidrug-Resistant Bacterial Colonization on Clinical Characteristics, Antibiotic Treatment, and Clinical Outcomes of Hospital-Acquired Pneumonia	16
Association of Cough Severity with Asthma Control and Quality of Life in Patients with Severe Asthma	16
Effectiveness of Inhalational Tranexamic Acid in Patients with Nonmassive Hemoptysis–A Systematic Review and Meta-Analysis	16
Osteoprotegerin is an Early Marker of the Fibrotic Process and of Antifibrotic Treatment Responses in Ex Vivo Lung Fibrosis	16
The Contribution of Carbapenem-Resistant Pseudomonas Aeruginosa Isolation to Clinical Outcomes in Hospitalized Patients with Exacerbations of Bronchiectasis: A Retrospective Cohort Study	15
Association of World Trade Center (WTC) Occupational Exposure Intensity with Chronic Obstructive Pulmonary Disease (COPD) and Asthma COPD Overlap (ACO)	15
Factors Influencing the Efficacy and Safety of Monoclonal Antibody Biologics in Chronic Obstructive Pulmonary Disease: A Meta-analysis of Randomized Controlled Trials	15
Efficacy and Safety of Superior Laryngeal Nerve Block in the Management of Neuropathic Cough: A Systematic Review	15
Tackling the Neuropathic Cough of Idiopathic Pulmonary Fibrosis (IPF): More Needs to be Done	14
The Down-Regulation of Lactoferrin Expression Induced by Cigarette Smoke can Induce Ferroptosis in COPD	14
Elastolysis in COPD: a Target for Therapy	14
Inhibition of Mettl3 by STM2457 and Loss of Macrophage Mettl3 Alleviate Pulmonary Hypertension and Right Heart Remodeling	14
PDE4B Modulates Phosphorylation of p65 (Ser468) via cAMP/PKA in Acute Lung Injury	13
The Advantages of FEV1 Percent Predicted Change During Bronchial Challenge Testing	13
Poly I:C Exacerbates Airway Inflammation and Remodeling in Cigarette Smoke-Exposed Mice	13
The Effect of Long-Term Azithromycin on Objective and Subjective Cough in Chronic Respiratory Disease: A Systematic Review and Meta-analysis of Randomised Controlled Trials and Noncomparative Studies	13
Effectiveness of Nintedanib in Progressive Pulmonary Fibrosis Assessed by Progression Criteria: An Italian, Observational, Multicenter Study	13
Diagnostic Accuracy of Breath Tests to Detect Pulmonary Tuberculosis: A Systematic Review	13
Supratherapeutic Inhaled Corticosteroid Use in Patients Initiating on Biologic Therapies for Severe Asthma: A Nationwide Cohort Study	13
Heat-Induced Secretion of Heat Shock Proteins 70 and 90 Does not Affect the Expression of the Glucocorticoid Receptor in Primary Airway Cells in COPD	13
Chronic Thromboembolic Pulmonary Hypertension	13
Factors Affecting Domiciliary Non-Invasive Ventilation Compliance	13
Prognostic Value of Geriatric Nutritional Risk Index for Patients with Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis	13
Exploration of IgE Specific to Staphylococcal Serine Protease-Like Protein A as a Phenotypic Marker in Late-Onset Asthma	12
Right Ventricular-Pulmonary Arterial Uncoupling Thresholds in Acute Pulmonary Embolism	12
Melatonin Protects Against Hyperoxia-Induced Apoptosis in Alveolar Epithelial type II Cells by Activating the MT2/PI3K/AKT/ETS1 Signaling Pathway	12
Tidal Breathing Analysis as a Prognostic Index for Airway Obstruction Trajectory and Asthma in Preterm Infants	12
Deep Learning Models for Predicting Malignancy Risk in CT-Detected Pulmonary Nodules: A Systematic Review and Meta-analysis	12
Surgical and Bronchoscopic Lung Volume Reduction for Severe Emphysema: A Systematic Review and Network Meta-analysis	11
Serum Soluble Toll-Like Receptor 4 is a Predictive Biomarker for Acute Exacerbation and Prognosis of Idiopathic Pulmonary Fibrosis: A Retrospective Study	11
Novel Robotic-Assisted Cryobiopsy for Peripheral Pulmonary Lesions	11
Pulmonary Protection from Left Ventricular Distension During Venoarterial Extracorporeal Membrane Oxygenation: Review and Management Algorithm	11
Analytic Morphomics in Myositis-Related Interstitial Lung Disease	11
Pulmonary Function and Quality of Life in Adults with Cystic Fibrosis	11
Canadian Health Care Professionals’ Familiarity with Chronic Cough Guidelines and Experiences with Diagnosis and Management: A Cross-Sectional Survey	10
Characterizing the Racial Discrepancy in Hypoxemia Detection in Venovenous Extracorporeal Membrane Oxygenation: An Extracorporeal Life Support Organization Registry Analysis	10
Quantitative Computed Tomography: What Clinical Questions Can it Answer in Chronic Lung Disease?	10
Anti-inflammatory Properties of the Alpha-Melanocyte-Stimulating Hormone in Models of Granulomatous Inflammation	10

Inhibition of Prostaglandin-Degrading Enzyme 15-PGDH Mitigates Acute Murine Lung Allograft Rejection	9
Circulating Osteopontin Predicts Clinical and Radiological Response in First-Line Treatment of Advanced Non-Small Cell Lung Cancer	9
The Lymphatic Highway: How Lymphatics Drive Lung Health and Disease	9
Stratifying GAP Stages by MUC5B rs35705950 T-Allele Carriage Refines Survival Prediction in IPF	9
Kappa and Mu Opioid Receptors in Chronic Cough: Current Evidence and Future Treatment	9
Pulmonary Fibrosis Diagnosis and Disease Progression Detected Via Hair Metabolome Analysis	9
Early Desaturation During 6-Minute Walk Test is a Predictor of Mortality in COPD	9
Genetic Factors Explain Half of the Individual Susceptibility to Chronic Bronchitis, Airflow Obstruction and COPD Regardless of the Spirometric Definition: A Nationwide Twin Study	9
COPD Risk Phenotypes in Older Smokers: Evaluation in GLI- and GOLD-Defined Respiratory Impairment	9
Identification of Idiopathic Pulmonary Fibrosis and Prediction of Disease Severity via Machine Learning Analysis of Comprehensive Metabolic Panel and Complete Blood Count Data	9
Overexpression of BPIFB4 Alleviates COPD Inflammatory Damage by Inhibiting M1 Macrophage Activation via the PI3K/AKT Pathway	9
Dasatinib-Associated Chylothorax: A Review of Cases Reported to the FDA Adverse Event Reporting System and the Published Literature	9
Assessment and Management of Cough in Idiopathic Pulmonary Fibrosis: A Narrative Review	8
Lung Transplantation in the United States for COVID-19 Related Lung Disease During the Pandemic	8
Efficacy of Biologics in Patients with Allergic Bronchopulmonary Aspergillosis: A Systematic Review and Meta-Analysis	8
Relationship Between Diaphragm Thickness, Thickening Fraction, Dome Excursion, and Respiratory Pressures in Healthy Subjects: An Ultrasound Study	8
Human Bronchial Epithelial Cell Transcriptome Changes in Response to Serum from Patients with Different Status of Inflammation	8
A Clinical Decision Tool for Risk Stratifying Patients with Systemic Sclerosis-Related Pulmonary Hypertension	8
Effects of Azithromycin on Blood Inflammatory Gene Expression and Cytokine Production in Sarcoidosis	8
Missing Nuts and Bolts: Translating Pulmonary Fibrosis from Preclinical Murine Models to Human Clinical Trials	7
Oxidative Stress and Epithelial–Mesenchymal Transition: The Impact of Ubiquitin C-terminal Hydrolase L1 in Cigarette Smoke-Induced COPD	7
Nebulized Tranexamic Acid in the Management of Hemoptysis: An Integrative Review	7
Elevated Eosinophil Counts in Acute Exacerbations of Bronchiectasis: Unveiling a Distinct Clinical Phenotype	7
Performance of the FORD Versus Other Available Models for the Noninvasive Prediction of Pulmonary Hypertension in Patients with Interstitial Lung Disease	7
Predictors of Initial CPAP Prescription and Subsequent Course with CPAP in Patients with Central Sleep Apneas at a Single Center	7
Emerging Therapeutics in COPD: Mapping Innovation to Treatable Traits	7
The Therapeutic Landscape in Chronic Cough	7
Feasibility and Utility of a Smartphone Application-Based Longitudinal Cough Monitoring in Chronic Cough Patients in a Real-World Setting	7
Bronchodilators in bronchiectasis: we urgently need more trials	7
Different Impacts of Blood and Sputum Eosinophil Counts on Lung Function and Clinical Outcomes in Asthma: Findings from the COREA Cohort	7
EUS-B-FNA Enhances the Diagnostic Yield of EBUS Bronchoscope for Intrathoracic Lesions	7
Synergistic Interactions Between the Quinolone-Derived Compound HT61 and Tobramycin Against a Range of Clinical Isolates of Pseudomonas aeruginosa In Vitro	7
Alveolar Epithelial Type 2 Cell Dysfunction in Idiopathic Pulmonary Fibrosis	6
Shortened Telomere Length in Sputum Cells of Bronchiectasis Patients is Associated with Dysfunctional Inflammatory Pathways	6
The Characteristics of the Concavity of Descending Limb of Maximal Expiratory Flow-Volume Curves Generated by Spirometry	6
Healthcare-Seeking Behaviour Due to Cough in Finnish Elderly: Too Much and Too Little	6
Prevalence and Predictors of Response to Antifibrotics in Long-Term Survivors with Idiopathic Pulmonary Fibrosis	6
Cytokines in Lung Transplantation	6
Mucus Transpiration as the Basis for Chronic Cough and Cough Hypersensitivity	6
Endobronchial Ultrasound Guided Transbronchial Needle Aspiration and PD-L1 Yields	6
Exhaled Volatile Organic Compounds Detection in Pneumonia Screening: A Comprehensive Meta-analysis	6
Airway Mucus Plugs in Patients with Chronic Cough: A Single-Center Observational Study	6
Relationship of Lung Function and the Preserved Ratio Impaired Spirometry Pattern with Aortic and Left Ventricular Structure and Function on Magnetic Resonance Imaging: The Jackson Heart Study	6
Adam19 Deficiency Impacts Pulmonary Function: Human GWAS Follow-up in a Mouse Knockout Model	6
Patient Perception of Cough in Interstitial Lung Disease; Impact of Cough Hypersensitivity	6
Modified Tracheobronchoplasty for Chronic Cough Due to Excessive Dynamic Airway Collapse: A Case Series	6
Serum Creatinine/Cystatin C Ratio as a Predictor of In-hospital Mortality in Patients Hospitalized with Acute Exacerbation of Chronic Obstructive Pulmonary Disease	6
Examination of Firefighting as an Occupational Exposure Criteria for Lung Cancer Screening	6
IgG Concentrations Distinguish People with Cystic Fibrosis and Mycobacterium abscessus	6
Efficacy and Safety of Dexmedetomidine in the Prone Position in Elderly Patients with Pneumonia: A Prospective, Double-Blind, Randomized Controlled Study	6
Impact of High-Grade Patterns in Early-Stage Lung Adenocarcinoma: A Multicentric Analysis	6
Acute Effect of Bronchodilator on Intrathoracic Airway Wall Compliance in COPD Patients	6
Commentary: Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: A Two‑Sample Mendelian Randomization Study	6
Sesamin Induces the Transdifferentiation of Type II Alveolar Epithelial Cells via AnnexinA1 and TRPV1	5
Association of Serum Biomarkers with Outcomes and Treatment Success of Inhaled Hyaluronan in COVID19	5
Association of Gas Diffusing Capacity of the Lung for Carbon Monoxide with Cardiovascular Morbidity and Survival in a Disadvantaged Clinical Population	5
The Cough Response to Inhaled Mannitol in Healthy Subjects	5
Plasma Reticulocalbin 3 (RCN3) is a Novel Biomarker for the Early Diagnosis of Hepatopulmonary Syndrome in Cirrhotic Patients	5
Lactate and Lactylation in Respiratory Diseases: from Molecular Mechanisms to Targeted Strategies	5
Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry	5
Respiratory Outcomes and Aspergillus Serology Following Elexacaftor/Tezacaftor/Ivacaftor Therapy in People with Cystic Fibrosis and a History of Aspergillus fumigatus Infection	5
Update 2025: Management of Non‑Small-Cell Lung Cancer	5
The Mitochondrial Fusion Promoter M1 Mitigates Cigarette Smoke-Induced Airway Inflammation and Oxidative Stress via the PI3K-AKT Signaling Pathway	5
Gut–lung Microbiota Interactions in Chronic Obstructive Pulmonary Disease (COPD): Potential Mechanisms Driving Progression to COPD and Epidemiological Data	5
Airway and Systemic Immunoglobulin Profiling and Immune Response in Adult Asthma	5
Disulfiram Alleviates MTX-Induced Pulmonary Fibrosis by Inhibiting EMT in Type 2 Alveolar Epithelial Cells	5
Outcomes of Extracorporeal Life Support (ECLS) in Acute Severe Asthma: A Narrative Review	5
The Effects of Diabetes on Gas Transfer Capacity, Lung Volumes, Muscle Strength, and Cardio-pulmonary Responses During Exercise	5
Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain: A Retrospective Multicenter Study	5
Estimating the Impact of Asthma and COPD on Lung Cancer Screening in the USA	5
Genomic Analysis Reveals the Prognostic and Immunotherapeutic Response Characteristics of Ferroptosis in Lung Squamous Cell Carcinoma	5
FLRT3 Overexpression Attenuates Ischemia–Reperfusion Induced Vascular Hyperpermeability and Lung Injury Through RND3	5
Clinical Relevance of Staphylococcus aureus Nasal Colonization and Staphylococcal Enterotoxin-Specific IgE Sensitization in Late-Onset Asthma	5
Nanopore-Based Metagenomic Sequencing in Respiratory Tract Infection: A Developing Diagnostic Platform	5
Cancer, Phase Angle and Sarcopenia: The Role of Diet in Connection with Lung Cancer Prognosis	5
Longitudinal Cough Frequency Monitoring in Persistent Coughers: Daily Variability and Predictability	5
The Decrease in Serum sRAGE Levels Upon Smoking is Associated with Activated Neutrophils	5
Effects of Pulmonary Rehabilitation Including Inspiratory Muscle Training in Patients with Chronic Obstructive Pulmonary Disease after Stratification by the Degree of Static Hyperinflation	4
Genetic Spectrum and Clinical Characteristics of Patients with Primary Ciliary Dyskinesia: a Belgian Single Center Study	4
Cyclophilin D Contributes to Airway Epithelial Mitochondrial Damage in Chronic Obstructive Pulmonary Disease	4

Differences in Blood Eosinophil Level During Stable Disease and During Exacerbation of COPD and Exacerbation Risks	4
Refractory Chronic Cough is all in Your Head?	4
Tiotropium in Patients with Bronchiectasis: A Prospective Cohort Study	4
Biologics in COPD: Do We Need a Divide and Conquer Approach?	4
Is Laryngeal Hypersensitivity Phenotype the Commonest Presentation Amongst Patients with Refractory Chronic Cough?	4
The Relationship Between Serum Angiotensin Converting Enzyme Level and the Decision to Escalate Treatment of Sarcoidosis	4
Lung Cancer Screening Penetration in an Urban Underserved County	4
Forced Vital Capacity and Low Frequency Reactance Area Measurements Are Associated with Asthma Control and Exacerbations	4
Decreasing Hospital Readmissions Utilizing an Evidence-Based COPD Care Bundle	4
The Diagnostic Efficiency and Safety of Transbronchial Lung Cryobiopsy Using 1.1-mm Cryoprobe in Diagnosing Interstitial Lung Disease	4
National Trends and Outcomes of Combined Lung–Liver Transplantation: An Analysis of the UNOS Registry	4
Use of Telomere Length as a Biomarker in Idiopathic Pulmonary Fibrosis	4
Comparative Efficacy of CFTR Modulators: A Network Meta-analysis	4
Plasma Lipid Profiling Identifies Phosphatidylcholine 34:3 and Triglyceride 52:3 as Potential Markers Associated with Disease Severity and Oxidative Status in Chronic Obstructive Pulmonary Disease	4
Clinical and Functional Outcomes Associated with Quality of Life in Patients with Lymphangioleiomyomatosis: A Cross-Sectional Study	4
The Associations of Long-Term Temperature and Precipitation with Chronic Respiratory Symptoms: Projections for the Changing Climate	4
ADAMTS7 Attenuates House Dust Mite-Induced Airway Inflammation and Th2 Immune Responses	4
Predictive Value of CT Biomarkers in Lung Transplantation Survival: Preliminary Investigation in a Diverse, Underserved, Urban Population	4
Effects of Active Chronic Cigarette-Smoke Exposure on Circulating Fibrocytes	4
Static Respiratory System Compliance as a Predictor of Extubation Failure in Patients with Acute Respiratory Failure	4
Is this the Dawning of AI for Sarcoidosis?	4
A Longitudinal Study of Respiratory Mechanics in Pregnant Women with Obesity and Overweight	4
Transcriptomic Expression of T2-Inflammation Genes in Peripheral Blood Mononuclear Cells and Longitudinal Clinical Outcomes in Asthma: Insights from the COREA Study	4