OOIR: Observatory of International Research

Papers

(The median citation count of Lung is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Hyperresponsiveness to Extracellular Acidification-Mediated Contraction in Isolated Bronchial Smooth Muscles of Murine Experimental Asthma	158
Serum Free Fatty Acid Concentration Predicts ARDS after Off-Pump CABG: A Prospective Observational Study	77
Roles of Pyruvate Kinase M2 in Pulmonary Diseases: What Do We Know So Far?	60
Lung Cancer in Never Smokers: Delving into Epidemiology, Genomic and Immune Landscape, Prognosis, Treatment, and Screening	47
Type 2 Biomarkers and Bronchiectasis	46
Genetic Testing Goes Beyond Imaging and Histological Evaluation in Pleuroparenchymal Fibroelastosis	42
Diaphragm Ultrasonography: Reference Values and Influencing Factors for Thickness, Thickening Fraction, and Excursion in the Seated Position	42
Cmpk2 Protects Against Acute Lung Injury in Mice	39
Lung Tissue Compliance Interacts with Smooth Muscle and Drives Hyperresponsiveness in Mice with Experimental Asthma	39
Lung Microbiome as a Treatable Trait in Chronic Respiratory Disorders	37
Illuminating Airway Nerve Structure and Function in Chronic Cough	36
Factors Associated with Corticosteroid Adherence in Sarcoidosis	36
Neutralization of CX3CL1 Attenuates TGF-β-Induced Fibroblast Differentiation Through NF-κB Activation and Mitochondrial Dysfunction in Airway Fibrosis	32
Prognostic Impact of Cancer Inflammation Prognostic Index for Non-small Cell Lung Cancer	31
Thoracic Ultrasound in COVID-19: Use of Lung and Diaphragm Ultrasound in Evaluating Dyspnea in Survivors of Acute Respiratory Distress Syndrome from COVID-19 Pneumonia in a Post-ICU Clinic	30
Pathophysiological Changes in Rhesus Monkeys with Paraquat-Induced Pulmonary Fibrosis	29
Associations of the Serum KL-6 with Severity and Prognosis in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease	28
LUNG Year in Review: 2024	27
Outcomes of Concomitant Cardiac Surgical Procedures Performed During Pediatric Lung Transplantation in the United States	26
First Exploration of the Altered Microbial Gut–Lung Axis in the Pathogenesis of Human Refractory Chronic Cough	25
Impact of Functional Status at the Time of Transplant on Short-Term Pediatric Lung Transplant Outcomes in the USA	24
Exhaled Breath Analysis Using a Novel Electronic Nose for Different Respiratory Disease Entities	23
Pseudomonas aeruginosa Infection and Inflammation in Cystic Fibrosis: A Pilot Study With Lung Explants and a Novel Histopathology Scoring System	23
Burden of Disease Associated with Refractory and Unexplained Chronic Cough in Canada: Results from a National Survey	23
Role of Slc7a11 in Bleomycin-Induced Lung Injury	22

Narrowing the Differential Diagnosis of Cystic Lesions in Smokers with Expiratory CT Acquisition Using the Cyst-Airway Communication Hypothesis	22
Authors’ Reply to Letter to the Editor Regarding the Article “Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: a Two-Sample Mendelian Randomization Study”	21
Lower Oxygen Tension and Intracranial Hemorrhage in Veno-venous Extracorporeal Membrane Oxygenation	20
Collagen-V and K-α-1 Tubulin Antibodies as Potential Markers of Unsuspected GERD-Related Lung Damage: Insights from a Cross-Sectional Analysis	20
Real-Life Response to Biologics in Severe Asthma with Nasal Polyposis: Insights from the Belgian Severe Asthma Registry	20
The Association Between Insulin Use and Asthma: An Epidemiological Observational Analysis and Mendelian Randomization Study	19
Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: A Two-Sample Mendelian Randomization Study	18
Prophylactic Inhaled Antibiotics for Ventilator-Associated Pneumonia: A Systematic Review and Meta-Analysis of Incidence and Mortality Outcomes	18
Percent Predicted vs. Absolute Six-Minute Walk Distance as Predictors of Lung Transplant-Free Survival in Fibrosing Interstitial Lung Diseases	17
Current Applications of Artificial Intelligence in Sarcoidosis	17
Osteoprotegerin is an Early Marker of the Fibrotic Process and of Antifibrotic Treatment Responses in Ex Vivo Lung Fibrosis	17
Association of World Trade Center (WTC) Occupational Exposure Intensity with Chronic Obstructive Pulmonary Disease (COPD) and Asthma COPD Overlap (ACO)	17
MMP19 Variants in Familial and Sporadic Idiopathic Pulmonary Fibrosis	17
Impact of Multidrug-Resistant Bacterial Colonization on Clinical Characteristics, Antibiotic Treatment, and Clinical Outcomes of Hospital-Acquired Pneumonia	16
Association of Cough Severity with Asthma Control and Quality of Life in Patients with Severe Asthma	16
Efficacy and Safety of Superior Laryngeal Nerve Block in the Management of Neuropathic Cough: A Systematic Review	15
Tackling the Neuropathic Cough of Idiopathic Pulmonary Fibrosis (IPF): More Needs to be Done	15
The Contribution of Carbapenem-Resistant Pseudomonas Aeruginosa Isolation to Clinical Outcomes in Hospitalized Patients with Exacerbations of Bronchiectasis: A Retrospective Cohort Study	15
Inhibition of Mettl3 by STM2457 and Loss of Macrophage Mettl3 Alleviate Pulmonary Hypertension and Right Heart Remodeling	15
Effectiveness of Inhalational Tranexamic Acid in Patients with Nonmassive Hemoptysis–A Systematic Review and Meta-Analysis	15
Elastolysis in COPD: a Target for Therapy	15
The Down-Regulation of Lactoferrin Expression Induced by Cigarette Smoke can Induce Ferroptosis in COPD	15
PDE4B Modulates Phosphorylation of p65 (Ser468) via cAMP/PKA in Acute Lung Injury	14
Effectiveness of Nintedanib in Progressive Pulmonary Fibrosis Assessed by Progression Criteria: An Italian, Observational, Multicenter Study	14
Heat-Induced Secretion of Heat Shock Proteins 70 and 90 Does not Affect the Expression of the Glucocorticoid Receptor in Primary Airway Cells in COPD	14
Factors Influencing the Efficacy and Safety of Monoclonal Antibody Biologics in Chronic Obstructive Pulmonary Disease: A Meta-analysis of Randomized Controlled Trials	14
Supratherapeutic Inhaled Corticosteroid Use in Patients Initiating on Biologic Therapies for Severe Asthma: A Nationwide Cohort Study	13
Poly I:C Exacerbates Airway Inflammation and Remodeling in Cigarette Smoke-Exposed Mice	13
The Effect of Long-Term Azithromycin on Objective and Subjective Cough in Chronic Respiratory Disease: A Systematic Review and Meta-analysis of Randomised Controlled Trials and Noncomparative Studies	13
Diagnostic Accuracy of Breath Tests to Detect Pulmonary Tuberculosis: A Systematic Review	13
Exploration of IgE Specific to Staphylococcal Serine Protease-Like Protein A as a Phenotypic Marker in Late-Onset Asthma	12
Tidal Breathing Analysis as a Prognostic Index for Airway Obstruction Trajectory and Asthma in Preterm Infants	12
Serum Soluble Toll-Like Receptor 4 is a Predictive Biomarker for Acute Exacerbation and Prognosis of Idiopathic Pulmonary Fibrosis: A Retrospective Study	12
The Advantages of FEV1 Percent Predicted Change During Bronchial Challenge Testing	12
Right Ventricular-Pulmonary Arterial Uncoupling Thresholds in Acute Pulmonary Embolism	12
Melatonin Protects Against Hyperoxia-Induced Apoptosis in Alveolar Epithelial type II Cells by Activating the MT2/PI3K/AKT/ETS1 Signaling Pathway	12
Prognostic Value of Geriatric Nutritional Risk Index for Patients with Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis	12
Surgical and Bronchoscopic Lung Volume Reduction for Severe Emphysema: A Systematic Review and Network Meta-analysis	11
Analytic Morphomics in Myositis-Related Interstitial Lung Disease	11
Deep Learning Models for Predicting Malignancy Risk in CT-Detected Pulmonary Nodules: A Systematic Review and Meta-analysis	11
Novel Robotic-Assisted Cryobiopsy for Peripheral Pulmonary Lesions	11
Pulmonary Protection from Left Ventricular Distension During Venoarterial Extracorporeal Membrane Oxygenation: Review and Management Algorithm	10
Genetic Factors Explain Half of the Individual Susceptibility to Chronic Bronchitis, Airflow Obstruction and COPD Regardless of the Spirometric Definition: A Nationwide Twin Study	10
Early Desaturation During 6-Minute Walk Test is a Predictor of Mortality in COPD	10
Pulmonary Fibrosis Diagnosis and Disease Progression Detected Via Hair Metabolome Analysis	10
Characterizing the Racial Discrepancy in Hypoxemia Detection in Venovenous Extracorporeal Membrane Oxygenation: An Extracorporeal Life Support Organization Registry Analysis	10
Identification of Idiopathic Pulmonary Fibrosis and Prediction of Disease Severity via Machine Learning Analysis of Comprehensive Metabolic Panel and Complete Blood Count Data	10
Overexpression of BPIFB4 Alleviates COPD Inflammatory Damage by Inhibiting M1 Macrophage Activation via the PI3K/AKT Pathway	10
Pulmonary Function and Quality of Life in Adults with Cystic Fibrosis	10
Circulating Osteopontin Predicts Clinical and Radiological Response in First-Line Treatment of Advanced Non-Small Cell Lung Cancer	10

Canadian Health Care Professionals’ Familiarity with Chronic Cough Guidelines and Experiences with Diagnosis and Management: A Cross-Sectional Survey	9
Stratifying GAP Stages by MUC5B rs35705950 T-Allele Carriage Refines Survival Prediction in IPF	9
The Lymphatic Highway: How Lymphatics Drive Lung Health and Disease	9
Dasatinib-Associated Chylothorax: A Review of Cases Reported to the FDA Adverse Event Reporting System and the Published Literature	9
Assessment and Management of Cough in Idiopathic Pulmonary Fibrosis: A Narrative Review	9
Kappa and Mu Opioid Receptors in Chronic Cough: Current Evidence and Future Treatment	9
COPD Risk Phenotypes in Older Smokers: Evaluation in GLI- and GOLD-Defined Respiratory Impairment	9
Inhibition of Prostaglandin-Degrading Enzyme 15-PGDH Mitigates Acute Murine Lung Allograft Rejection	9
Predictors of Initial CPAP Prescription and Subsequent Course with CPAP in Patients with Central Sleep Apneas at a Single Center	8
The Therapeutic Landscape in Chronic Cough	8
Different Impacts of Blood and Sputum Eosinophil Counts on Lung Function and Clinical Outcomes in Asthma: Findings from the COREA Cohort	8
Efficacy of Biologics in Patients with Allergic Bronchopulmonary Aspergillosis: A Systematic Review and Meta-Analysis	8
Oxidative Stress and Epithelial–Mesenchymal Transition: The Impact of Ubiquitin C-terminal Hydrolase L1 in Cigarette Smoke-Induced COPD	8
A Clinical Decision Tool for Risk Stratifying Patients with Systemic Sclerosis-Related Pulmonary Hypertension	8
Emerging Therapeutics in COPD: Mapping Innovation to Treatable Traits	8
Lung Transplantation in the United States for COVID-19 Related Lung Disease During the Pandemic	8
Relationship Between Diaphragm Thickness, Thickening Fraction, Dome Excursion, and Respiratory Pressures in Healthy Subjects: An Ultrasound Study	8
EUS-B-FNA Enhances the Diagnostic Yield of EBUS Bronchoscope for Intrathoracic Lesions	8
Effects of Azithromycin on Blood Inflammatory Gene Expression and Cytokine Production in Sarcoidosis	8
Bronchodilators in bronchiectasis: we urgently need more trials	8
Human Bronchial Epithelial Cell Transcriptome Changes in Response to Serum from Patients with Different Status of Inflammation	8
Alveolar Epithelial Type 2 Cell Dysfunction in Idiopathic Pulmonary Fibrosis	7
Examination of Firefighting as an Occupational Exposure Criteria for Lung Cancer Screening	7
Performance of the FORD Versus Other Available Models for the Noninvasive Prediction of Pulmonary Hypertension in Patients with Interstitial Lung Disease	7
IgG Concentrations Distinguish People with Cystic Fibrosis and Mycobacterium abscessus	7
Efficacy and Safety of Dexmedetomidine in the Prone Position in Elderly Patients with Pneumonia: A Prospective, Double-Blind, Randomized Controlled Study	7
Airway Mucus Plugs in Patients with Chronic Cough: A Single-Center Observational Study	7
Synergistic Interactions Between the Quinolone-Derived Compound HT61 and Tobramycin Against a Range of Clinical Isolates of Pseudomonas aeruginosa In Vitro	7
Nebulized Tranexamic Acid in the Management of Hemoptysis: An Integrative Review	7
The Characteristics of the Concavity of Descending Limb of Maximal Expiratory Flow-Volume Curves Generated by Spirometry	7
Feasibility and Utility of a Smartphone Application-Based Longitudinal Cough Monitoring in Chronic Cough Patients in a Real-World Setting	7
Serum Creatinine/Cystatin C Ratio as a Predictor of In-hospital Mortality in Patients Hospitalized with Acute Exacerbation of Chronic Obstructive Pulmonary Disease	7
Elevated Eosinophil Counts in Acute Exacerbations of Bronchiectasis: Unveiling a Distinct Clinical Phenotype	7
Missing Nuts and Bolts: Translating Pulmonary Fibrosis from Preclinical Murine Models to Human Clinical Trials	7
Exhaled Volatile Organic Compounds Detection in Pneumonia Screening: A Comprehensive Meta-analysis	7
Endobronchial Ultrasound Guided Transbronchial Needle Aspiration and PD-L1 Yields	7
Disulfiram Alleviates MTX-Induced Pulmonary Fibrosis by Inhibiting EMT in Type 2 Alveolar Epithelial Cells	6
Modified Tracheobronchoplasty for Chronic Cough Due to Excessive Dynamic Airway Collapse: A Case Series	6
Prevalence and Predictors of Response to Antifibrotics in Long-Term Survivors with Idiopathic Pulmonary Fibrosis	6
Clinical Relevance of Staphylococcus aureus Nasal Colonization and Staphylococcal Enterotoxin-Specific IgE Sensitization in Late-Onset Asthma	6
Gut–lung Microbiota Interactions in Chronic Obstructive Pulmonary Disease (COPD): Potential Mechanisms Driving Progression to COPD and Epidemiological Data	6
Plasma Reticulocalbin 3 (RCN3) is a Novel Biomarker for the Early Diagnosis of Hepatopulmonary Syndrome in Cirrhotic Patients	6
Lactate and Lactylation in Respiratory Diseases: from Molecular Mechanisms to Targeted Strategies	6
FLRT3 Overexpression Attenuates Ischemia–Reperfusion Induced Vascular Hyperpermeability and Lung Injury Through RND3	6
Association of Gas Diffusing Capacity of the Lung for Carbon Monoxide with Cardiovascular Morbidity and Survival in a Disadvantaged Clinical Population	6
Cytokines in Lung Transplantation	6
Healthcare-Seeking Behaviour Due to Cough in Finnish Elderly: Too Much and Too Little	6
Impact of High-Grade Patterns in Early-Stage Lung Adenocarcinoma: A Multicentric Analysis	6
Airway and Systemic Immunoglobulin Profiling and Immune Response in Adult Asthma	6
The Mitochondrial Fusion Promoter M1 Mitigates Cigarette Smoke-Induced Airway Inflammation and Oxidative Stress via the PI3K-AKT Signaling Pathway	6
Nanopore-Based Metagenomic Sequencing in Respiratory Tract Infection: A Developing Diagnostic Platform	6
The Cough Response to Inhaled Mannitol in Healthy Subjects	6
Commentary: Genetic Association of Circulating Adipokines with Risk of Idiopathic Pulmonary Fibrosis: A Two‑Sample Mendelian Randomization Study	6
Relationship of Lung Function and the Preserved Ratio Impaired Spirometry Pattern with Aortic and Left Ventricular Structure and Function on Magnetic Resonance Imaging: The Jackson Heart Study	6
Mucus Transpiration as the Basis for Chronic Cough and Cough Hypersensitivity	6
Adam19 Deficiency Impacts Pulmonary Function: Human GWAS Follow-up in a Mouse Knockout Model	6
Patient Perception of Cough in Interstitial Lung Disease; Impact of Cough Hypersensitivity	6
Estimating the Impact of Asthma and COPD on Lung Cancer Screening in the USA	6
Association of Serum Biomarkers with Outcomes and Treatment Success of Inhaled Hyaluronan in COVID19	6
The Effects of Diabetes on Gas Transfer Capacity, Lung Volumes, Muscle Strength, and Cardio-pulmonary Responses During Exercise	5
Differences in Blood Eosinophil Level During Stable Disease and During Exacerbation of COPD and Exacerbation Risks	5
Static Respiratory System Compliance as a Predictor of Extubation Failure in Patients with Acute Respiratory Failure	5
Comparative Efficacy of CFTR Modulators: A Network Meta-analysis	5
Longitudinal Cough Frequency Monitoring in Persistent Coughers: Daily Variability and Predictability	5
Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry	5
Update 2025: Management of Non‑Small-Cell Lung Cancer	5
Tiotropium in Patients with Bronchiectasis: A Prospective Cohort Study	5
Effects of Active Chronic Cigarette-Smoke Exposure on Circulating Fibrocytes	5
A Longitudinal Study of Respiratory Mechanics in Pregnant Women with Obesity and Overweight	5
The Diagnostic Efficiency and Safety of Transbronchial Lung Cryobiopsy Using 1.1-mm Cryoprobe in Diagnosing Interstitial Lung Disease	5
Sesamin Induces the Transdifferentiation of Type II Alveolar Epithelial Cells via AnnexinA1 and TRPV1	5
Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain: A Retrospective Multicenter Study	5
Outcomes of Extracorporeal Life Support (ECLS) in Acute Severe Asthma: A Narrative Review	5
Use of Telomere Length as a Biomarker in Idiopathic Pulmonary Fibrosis	5
National Trends and Outcomes of Combined Lung–Liver Transplantation: An Analysis of the UNOS Registry	5
Is this the Dawning of AI for Sarcoidosis?	5
Respiratory Outcomes and Aspergillus Serology Following Elexacaftor/Tezacaftor/Ivacaftor Therapy in People with Cystic Fibrosis and a History of Aspergillus fumigatus Infection	5
The Decrease in Serum sRAGE Levels Upon Smoking is Associated with Activated Neutrophils	5