Archives of Toxicology

Article	Citations
A modular strategy for the testing and assessment of non-genotoxic carcinogens	894
Optimized methods for measuring competitive binding of chemical substances to thyroid hormone distributor proteins transthyretin and thyroxine binding globulin	270
Cell–cell contacts prevent t-BuOOH-triggered ferroptosis and cellular damage in vitro by regulation of intracellular calcium	246
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity	145
miR-451a and miR-486-5p: biomarkers for benzene-induced hematotoxicity	131
Induction of clastogenesis and gene mutations by carbamazepine (at its therapeutically effective serum levels) in mammalian cells and the dependence on human CYP2B6 enzyme activity	101
Influence of deoxynivalenol and zearalenone on the immunohistochemical expression of oestrogen receptors and liver enzyme genes in vivo in prepubertal gilts	93
SIRT3/GLUT4 signaling activation by metformin protect against cisplatin-induced ototoxicity in vitro	89
Novel insight into mechanisms for ATR activation by chromatin structures	84
Developmental brain lipidomics is influenced by postnatal chlorpyrifos exposure and APOE genetic background in mice	81
Single-cell RNA sequencing to reveal non-parenchymal cell heterogeneity and immune network of acetaminophen-induced liver injury in mice	73
7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells	72
Estimating the reduction in US mortality if cigarettes were largely replaced by e-cigarettes	70
Comprehensive ubiquitome analysis reveals persistent mitochondrial remodeling disruptions from doxorubicin-induced cardiotoxicity in aged CD-1 male mice	70
Sex-specific differences in toxicology: does the sex make the poison?	67
Unraveling the Hsp70-ROS-autophagy axis in pentachlorophenol-challenged lung and liver epithelial cells	63
Neonatal opioid toxicity: opioid withdrawal (abstinence) syndrome with emphasis on pharmacogenomics and respiratory depression	62
Impaired intestinal stem cell activity in ETEC infection: enterotoxins, cyclic nucleotides, and Wnt signaling	62
The role of redox signaling in mitochondria and endoplasmic reticulum regulation in kidney diseases	60
Mystery of methamphetamine-induced autophagosome accumulation in hippocampal neurons: loss of syntaxin 17 in defects of dynein–dynactin driving and autophagosome–late endosome/lysosome fusion	59
Investigating the applicability domain of the hiPSC-based PluriLum assay: an embryotoxicity assessment of chemicals and drugs	58
Activation of (un)regulated cell death as a new perspective for bispyridinium and imidazolium oximes	57
Exposure limits for indoor volatile substances concerning the general population: The role of population-based differences in sensory irritation of the eyes and airways for assessment factors	56
Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice	56
Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds—a hypo	55

Canine coronavirus infection is intensified by 2,3,7,8-tetrachlorodibenzo-p-dioxin	51
The role of genetic polymorphisms for inducing genotoxicity in workers occupationally exposed to benzene: a systematic review	51
Laser vs. thermal treatments of green pigment PG36: coincidence and toxicity of processes	47
Metabolism-mediated cytotoxicity and genotoxicity of pyrrolizidine alkaloids	46
Coenzyme Q0 defeats NLRP3-mediated inflammation, EMT/metastasis, and Warburg effects by inhibiting HIF-1α expression in human triple-negative breast cancer cells	45
Yttrium chloride-induced cytotoxicity and DNA damage response via ROS generation and inhibition of Nrf2/PPARγ pathways in H9c2 cardiomyocytes	44
Dynamically monitoring cellular γ-H2AX reveals the potential of carcinogenicity evaluation for genotoxic compounds	44
In vitro metabolism of helenalin and its inhibitory effect on human cytochrome P450 activity	42
N-acetyltransferase 2 acetylator genotype-dependent N-acetylation and toxicity of the arylamine carcinogen β-naphthylamine in cryopreserved human hepatocytes	41
Effects of low concentrations of ozone gas exposure on percutaneous oxygen saturation and inflammatory responses in a mouse model of Dermatophagoides farinae-induced asthma	40
ITGA1, the alpha 1 subunit of integrin receptor, is a novel marker of drug-resistant senescent melanoma cells in vitro	40
Perfluoroalkyl substances (PFASs) are substrates of the renal human organic anion transporter 4 (OAT4)	39
Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell models	38
Application of physiologically based (PBK) modeling to quantify the effect of the antibiotic tobramycin on bile acid levels in human plasma	38
Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole ‘nitazene’ synthetic opioid	37
What do we currently know about Novichoks? The state of the art	37
Identification, synthesis and quantification of eutylone consumption markers in a chemsex context	36
Apelin-13 protects against cisplatin-induced ototoxicity by inhibiting apoptosis and regulating STAT1 and STAT3	35
In vitro-in silico analysis reveals that loss of tankyrase1/2 improves bile acid handling in genetically engineered HepG2 cultures	35
Impact of plastic-related compounds on the gene expression signature of HepG2 cells transfected with CYP3A4	34
Combined use of multiparametric high-content-screening and in vitro circadian reporter assays in neurotoxicity evaluation	34
Nε-(1-Carboxymethyl)-L-lysine, an advanced glycation end product, exerts malignancy on chondrosarcoma via the activation of cancer stemness	34
Toxicokinetics of benzotriazole UV stabilizer UV-P in humans after single oral administration	34
In silico structural and mechanistic sights into the N-glycosidase mechanism of Shiga toxin	33
Evaluation of the toxicity of combustion smokes at the air–liquid interface: a comparison between two lung cell models and two exposure methods	32
Internal exposure to heat-induced food contaminants in omnivores, vegans and strict raw food eaters: biomarkers of exposure to 2- and 3-monochloropropanediol (urinary excretion) and glycidol (hemoglob	32
Acute exposure to microcystin-LR induces hepatopancreas toxicity in the Chinese mitten crab (Eriocheir sinensis)	32
Development of a transcriptome-based determination of innate immune suppressor (TDIS) assay as an in vitro test for immunotoxicity	32
Dipyanone, a new methadone-like synthetic opioid: In vitro and in vivo human metabolism and pharmacological profiling	31
Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis	31
Comparative metabolism of aflatoxin B1 in mouse, rat and human primary hepatocytes using HPLC–MS/MS	31
Polymorphisms of an oncogenic gene, mesothelin, predict the risk and prognosis of gastric cancer in a Chinese Han population	30
Recent research on Novichok	30
Impact of administration routes and dose frequency on the toxicology of SARS-CoV-2 mRNA vaccines in mice model	30
Correction to: Dynamics in zebrafish development define transcriptomic specificity after angiogenesis inhibitor exposure	29
A benchmark concentration-based strategy for evaluating the combined effects of genotoxic compounds in TK6 cells	29
Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment	29
Time for CHANGE: system-level interventions for bringing forward the date of effective use of NAMs in regulatory toxicology	28
Toxicity of ACP-105: a substance used as doping in sports: application of in silico methods for prediction of selected toxicological endpoints	28
Low-dose tributyltin triggers human chondrocyte senescence and mouse articular cartilage aging	28
Targeting MLKL ameliorates T-2 toxin-induced cartilage damage by inhibiting chondrocyte death and matrix degradation in mice	28
Higher paracetamol levels are associated with elevated glucocorticoid concentrations in hair: findings from a large cohort of young adults	28
Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes	27
Involvement of mitochondrial dynamics and mitophagy in diabetic endothelial dysfunction and cardiac microvascular injury	27
Muller and mutations: mouse study of George Snell (a postdoc of Muller) fails to confirm Muller’s fruit fly findings, and Muller fails to cite Snell’s findings	26
Response to 10.1007/s00204-022-03330-1 by Prof. D.A. Ribeiro ‘What are the criteria and conditions for performing the micronucleus assay in oral exfoliated cells from children continuously exposed to	25
Progress in retinal toxicity research	25
Evaluating the in vitro developmental toxicity potency of a series of petroleum substance extracts using new approach methodologies (NAMs)	25
Evaluation of developmental toxicity of chlorpyrifos through new approach methodologies: a systematic review	25
Liver transcriptome analyses of acute poisoning and recovery of male ICR mice exposed to the mushroom toxin α-amanitin	24

Development of a novel in vitro respiratory sensitization assay and its application in an integrated testing strategy (ITS)	23
Quo vadis blood protein adductomics?	23
Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents	23
Mitigation of depleted uranium-induced mitochondrial damage by ethylmalonic encephalopathy 1 protein via modulation of hydrogen sulfide and glutathione pathways	23
Repetitive diacetyl vapor exposure promotes ubiquitin proteasome stress and precedes bronchiolitis obliterans pathology	23
Physiologically based kinetic modelling predicts the in vivo relative potency of riddelliine N-oxide compared to riddelliine in rat to be dose dependent	22
Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice	22
Categorizing the characteristics of human carcinogens: a need for specificity	22
Optimization of the IL-2 Luc assay for immunosuppressive drugs: a novel in vitro immunotoxicity test with high sensitivity and predictivity	22
A systematic evaluation of the cucurbit[7]uril pharmacokinetics and toxicity after a single dose and short-term repeated administration in mice	22
Toxicity assessment of flavour chemicals used in e-cigarettes: current state and future challenges	22
Metabolism study of two phenethylamine − derived new psychoactive substances using in silico, in vivo, and in vitro approaches	21
E-cigarettes increase the risk of adenoma formation in murine colorectal cancer model	21
A comparison of the chemo- and radiotoxicity of thorium and uranium at different enrichment grades	21
Human metabolism and excretion kinetics of the surfactant 2,4,7,9-tetramethyl-5-decyne-4,7-diol (TMDD) after oral and dermal administration	21
In vitro to in vivo extrapolation to derive a metabolism factor for estimating the aggregate exposure to salicylic acid after dermal exposure of its esters	21
The presence of carcinogenic compounds in gene-edited NGOs causes cancer in humans	21
Correction: Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes	21
Molecular docking and molecular dynamics simulations revealed interaction mechanism of acetylcholinesterase with organophosphorus pesticides and their alternatives	21
Species-differences in the in vitro biotransformation of trifluoroethene (HFO-1123)	21
Involvement of gut microbiota in chlorpyrifos-induced subchronic toxicity in mice	21
High molecular weight polycyclic aromatic hydrocarbon (HMW-PAH) isomers: unveiling distinct toxic effects from cytotoxicity to oxidative stress-induced DNA damage	20
Extending the viability of human precision-cut intestinal slice model for drug metabolism studies	20
Associations among global long interspersed nuclear element-1 DNA methylation, metal exposure, and chronic kidney disease	20
Therapeutic potential of 4-phenylbutyric acid against methylmercury-induced neuronal cell death in mice	20
Evaluation of genetic variants in nucleosome remodeling and deacetylase (NuRD) complex subunits encoding genes and gastric cancer susceptibility	20
Development of two ultra-sensitive UHPLC–QqQ-MS/MS methods for the simultaneous determination of hydroxyzine and its active metabolite (cetirizine) in human blood: applications to real cases of forens	20
Artificial intelligence (AI)—it’s the end of the tox as we know it (and I feel fine)*	19
Genotoxicity and safety pharmacology of the rVSVInd(GML)-mspSGtc vaccine against SARS-CoV-2 in Sprague–Dawley rats and Beagle dogs	19
First identification, chemical analysis and pharmacological characterization of N-piperidinyl etonitazene (etonitazepipne), a recent addition to the 2-benzylbenzimidazole opioid subclass	19
Kinetically-derived maximal dose (KMD) indicates lack of human carcinogenicity of ethylbenzene	19
Impact of perfluoroalkyl substances (PFAS) and PFAS mixtures on lipid metabolism in differentiated HepaRG cells as a model for human hepatocytes	19
Tat_BioV: tattoo ink exposure and biokinetics of selected tracers in a short-term clinical study of 24 subjects	19
Inhalation of hydrogenated vegetable oil combustion exhaust and genotoxicity responses in humans	19
Caspase-3/GSDME dependent pyroptosis contributes to offspring lung injury induced by gestational PFOS exposure via PERK/ATF4 signaling	19
Multi-omics and multi-stages integration identified a novel variant associated with silicosis risk	19
Cyanobacterial harmful bloom lipopolysaccharides: pro-inflammatory effects on epithelial and immune cells in vitro	19
Flavonoids commonly induce hormetic responses	19
T-2 toxin-induced splenic injury by disrupting the gut microbiota–spleen axis via promoting IL-6/JAK/STAT1 signaling-mediated inflammation and apoptosis and its mitigation by elemental nano-selenium	19
Duplex sequencing provides detailed characterization of mutation frequencies and spectra in the bone marrow of MutaMouse males exposed to procarbazine hydrochloride	18
A urinary biomarker for monitoring exposures to 2,2,4-trimethyl-1,3-pentanediol monoisobutyrate and 2,2,4-trimethyl-1,3-pentanediol diisobutyrate in rats	18
Lack of CYP3A4 protein induction despite mRNA induction in primary hepatocytes exposed to rifabutin as a possible explanation for its low interaction risk in vivo	18
Vernonia amygdalina displays otoprotective effects via antioxidant pathway on cisplatin-induced hair cell loss in zebrafish	18
Differentiated SH-SY5Y neuroblastoma cells as a model for evaluation of nerve agent-associated neurotoxicity	18
Preliminary nonclinical safety and immunogenicity of an rVSV-ΔG-SARS-CoV-2-S vaccine in mice, hamsters, rabbits and pigs	18
A novel in vitro high-content imaging assay for the prediction of drug-induced lung toxicity	18
Catalytic activity and stereoselectivity of engineered phosphotriesterases towards structurally different nerve agents in vitro	18
Optimisation of the HepaRG cell line model for drug toxicity studies using two different cultivation conditions: advantages and limitations	18
Exploring the multifaceted impact of bisphosphonates on bone graft integration: transitioning from in vivo insights to clinical applications	18
In silico prediction of parkinsonian motor deficits-related neurotoxicants based on the adverse outcome pathway concept	18
Is there a relationship between orthodontic treatment and DNA damage? The relevance of metal ion accumulation in oral mucosa cells	18
Impact of Hedgehog modulators on signaling pathways in primary murine and human hepatocytes in vitro: insights into liver metabolism	18
A study of the pharmacokinetics of clozapine and its metabolites by the dynamics of its distribution in the oral fluid of healthy volunteers	18
The physiological and biochemical basis of potency thresholds modeled using human estrogen receptor alpha: implications for identifying endocrine disruptors	17
Chemobrain: mitoxantrone-induced oxidative stress, apoptotic and autophagic neuronal death in adult CD-1 mice	17
In vivo mutagenicity and tumor-promoting activity of 1,3-dichloro-2-propanol in the liver and kidneys of gpt delta rats	17
Extension and validation of a physiologically based toxicokinetic model for risk assessment of aluminium exposure in humans	17
Plasma biomarkers TAP, CPA1, and CPA2 for the detection of pancreatic injury in rat: the development of a novel multiplex IA-LC-MS/MS assay and biomarker performance evaluation	17
Effects of marine biotoxins on drug-metabolizing cytochrome P450 enzymes and their regulation in mammalian cells	17
Oxidative-stress and long-term hepatotoxicity: comparative study in Upcyte human hepatocytes and hepaRG cells	17
The thrombopoietin mimetic JNJ-26366821 reduces the late injury and accelerates the onset of liver recovery after acetaminophen-induced liver injury in mice	16
Metabolic activation of WHO-congeners PCB28, 52, and 101 by human CYP2A6: evidence from in vitro and in vivo experiments	16
Exploiting TRP channel diversity in insects: a pathway to next-generation pest management	16
Substance abuse and neurodegenerative diseases: focus on ferroptosis	16
Correction to: The explosive trinitrotoluene (TNT) induces gene expression of carbonyl reductase in the blue mussel (Mytilus spp.): a new promising biomarker for sea dumped war relicts?	16
Systematic review of genotoxicity induced by occupational exposure to antineoplastic drugs	16
A dual role for ERK-1/2 in the regulation of plasmin activity and cell migration in metastatic NSCLC-H1299 cells	16
Genotoxicity and inflammatory potential of stainless steel welding fume particles: an in vitro study on standard vs Cr(VI)-reduced flux-cored wires and the role of released metals	16
The hepatoprotective potential of ferulic acid against a spectrum of pharmaceuticals and toxic compounds	16
Vinpocetine protects against chloroquine-induced cardiotoxicity by mitigating oxidative stress	16
Sub-acute oral exposure to lowest observed adverse effect level of nivalenol exacerbates atopic dermatitis in mice via direct activation of mitogen-activated protein kinase signal in antigen-presentin	16
YES1 as a potential target to overcome drug resistance in EGFR-deregulated non-small cell lung cancer	16
Proteomic diversity of Russell's viper venom: exploring PLA2 isoforms, pharmacological effects, and inhibitory approaches	16
A mixture of 13 pesticides, contaminants, and food additives below individual NOAELs produces histopathological and organ weight changes in rats	16
Correction: Species-differences in the in vitro biotransformation of trifluoroethene (HFO-1123)	16
In vitro metabolism of Benzyl-4CN-BUTINACA and MDMB-4CN-BUTINACA using human hepatocytes and LC-QToF-MS analysis	15
Next generation risk assessment of human exposure to estrogens using safe comparator compound values based on in vitro bioactivity assays	15
Central role of Sigma-1 receptor in ochratoxin A-induced ferroptosis	15
Developments in high-resolution mass spectrometric analyses of new psychoactive substances	15
Identification of phase-I and phase-II metabolites and the metabolic pathway of the novel synthetic cannabinoid 5F-EDMB-PICA in vitro	15

Impact of indoor air pollution on DNA damage and chromosome stability: a systematic review	15
Cytotoxicity and genotoxicity of the carcinogen aristolochic acid I (AA-I) in human bladder RT4 cells	15
Internal exposure to heat-induced food contaminants in omnivores, vegans and strict raw food eaters: biomarkers of exposure to acrylamide (hemoglobin adducts, urinary mercapturic acids) and new insigh	15
A review of the scientific literature on experimental toxicity studies of COVID-19 vaccines, with special attention to publications in toxicology journals	15
A model-based approach to designing developmental toxicology experiments using sea urchin embryos	15
In vitro and in vivo protective potential of quercetin-3-glucuronide against lipopolysaccharide-induced pulmonary injury through dual activation of nuclear factor-erythroid 2 related factor 2 and auto	14
Modular air–liquid interface aerosol exposure system (MALIES) to study toxicity of nanoparticle aerosols in 3D-cultured A549 cells in vitro	14
Multi-omics bioactivity profile-based chemical grouping and read-across: a case study with Daphnia magna and azo dyes	14
Possum: identification and interpretation of potassium ion inhibitors using probabilistic feature vectors	14
Lysosomal dysfunction in Schwann cells is involved in bortezomib-induced peripheral neurotoxicity	14
Screening for ferroptosis genes related to endometrial carcinoma and predicting of targeted drugs based on bioinformatics	14
Development and validation of an automatic machine learning model to predict abnormal increase of transaminase in valproic acid-treated epilepsy	14
Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application	14
PBTK model-based analysis of CYP3A4 induction and the toxicokinetics of the pyrrolizidine alkaloid retrorsine in man	13
Replication stress: an early key event in ochratoxin a genotoxicity?	13
Cytogenotoxicity and inflammatory response in liver of rats exposed to different doses of cannabis nano emulsions	13
Connexins may play a critical role in cigarette smoke-induced pulmonary hypertension	13
Application of in silico methods to predict the acute toxicity of bicyclic organophosphorus compounds as potential chemical weapon	13
Toxicokinetics of plasmatic VX in a swine model: comparison of a simple enzymatic titration method with a mass spectrometry method	13
Exposure of intestinal explants to NX, but not to DON, enriches the secretome in mitochondrial proteins	13
Dopaminergic and serotonergic changes in rabbit fetal brain upon repeated gestational exposure to diesel engine exhaust	13
Characterization of pathological changes in the olfactory system of mice exposed to methylmercury	13
Towards the mechanism of spermatotoxicity of p-tert-butyl-alpha-methylhydrocinnamic aldehyde: inhibition of late stage ex-vivo spermatogenesis in rat seminiferous tubule cultures by para-tert-butyl- b	13
In vitro approaches to investigate the effect of chemicals on antibody production: the case study of PFASs	13
Metabolism of alcohol ethoxylates (AEs) in rat, hamster, and human hepatocytes and liver S9: a pilot study for metabolic stability, metabolic pathway, and metabolites identification in vitro and in si	13
Cannabidiol disrupts apoptosis, autophagy and invasion processes of placental trophoblasts	12
Contribution to the ongoing discussion on fluoride toxicity	12
Immunomodulation and exposure to per- and polyfluoroalkyl substances: an overview of the current evidence from animal and human studies	12
Developing urinary pyrrole–amino acid adducts as non-invasive biomarkers for identifying pyrrolizidine alkaloids-induced liver injury in human	12
Metabolic dysfunction-associated steatotic liver disease-induced changes in the antioxidant system: a review	12
The entactogen 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) as a treatment aid in psychotherapy and its safety concerns	12
Dynamics in zebrafish development define transcriptomic specificity after angiogenesis inhibitor exposure	12
OCT1-dependent uptake of structurally diverse pyrrolizidine alkaloids in human liver cells is crucial for their genotoxic and cytotoxic effects	12
In silico analysis decodes transthyretin (TTR) binding and thyroid disrupting effects of per- and polyfluoroalkyl substances (PFAS)	12
Thifluzamide exposure induced neuro-endocrine disrupting effects in zebrafish (Danio rerio)	12
Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh	12
Drug-induced hepatic sinusoidal obstruction syndrome: current advances and future perspectives	12
Hepatic metabolism of chlorinated derivatives of bisphenol A (ClxBPA) and interspecies differences between rats and humans	12
Mouse innate-like B-1 lymphocytes promote inhaled particle-induced in vitro granuloma formation and inflammation in conjunction with macrophages	12
Accumulation of chlorinated paraffins in adipocytes is determined by cellular lipid content and chlorination level	12
A novel approach to calculating the kinetically derived maximum dose	12
Comparison of comet-based approaches to assess base excision repair	12
Unanticipated differences in the rat plasma metabolome of genistein and daidzein	12
Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice	12
New aspects in snake venom toxicology	12
Particulate and drug-induced toxicity assessed in novel quadruple cell human primary hepatic disease models of steatosis and pre-fibrotic NASH	11
Molecular mechanisms of environmental pollutant-induced cartilage damage: from developmental disorders to osteoarthritis	11
Effects of chronic insecticide exposure on neuronal network development in vitro in rat cortical cultures	11
Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning	11
Compromised blood–bile barrier after acetaminophen overdose	11
Correction to: Cytotoxicity of Prymnesium parvum extracts and prymnesin analogs on epithelial fish gill cells RTgill-W1 and the human colon cell line HCEC-1CT	11
In vitro studies on the dependence of drug deposition in dentin on drug concentration, contact time, and the physicochemical properties of the drugs	11
Heavy metals: toxicity and human health effects	11
The EU chemicals strategy for sustainability: critical reflections on proposed regulatory changes for endocrine disruptors and mixture toxicity	11
SIRT3 regulates PFKFB3-mediated glycolysis to attenuate cisplatin-induced ototoxicity both in vivo and in vitro	11
Role of paraoxonase 1 in organophosphate G-series nerve agent poisoning and future therapeutic strategies	11
Fasting augments pyrrolizidine alkaloid-induced hepatotoxicity	11
Elevated risk of adverse effects from foodborne contaminants and drugs in inflammatory bowel disease: a review	11
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment	11
Sirtuins as molecular targets, mediators, and protective agents in metal-induced toxicity	11
Effects of postnatal exposure to tetrabromobisphenol A on testis development in mice and early key events	11
Correction: Grouping of chemicals for safety assessment: the importance of toxicokinetic properties of salicylate esters	11
Multi-omics analysis reveals metabolism of okadaic acid in gut lumen of rat	11
How to avoid misinterpretation of dual reporter gene assay data affected by cell damage	11
Future in the past: paternal reprogramming of offspring phenotype and the epigenetic mechanisms	11
Is micronucleus test a suitable method for monitoring oral mucosa exposed to dental bleachings in smokers?	10
Alterations in the proteomes of HepG2 and IHKE cells inflicted by six selected mycotoxins	10
The current state of EVALI research (electronic cigarettes or vaping product use-associated lung injury)	10
Obituary: Eugenio Vilanova	10
Functional metabolomics characterizes the contribution of farnesoid X receptor in pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome	10
Organotin and organochlorine toxicants activate key translational regulatory proteins in human immune cells	10
Intracellular hydrogen sulfide induces stress granule formation and translational repression through eIF2α phosphorylation	10
Combined biological effects and lung proteomics analysis in mice reveal different toxic impacts of electronic cigarette aerosol and combustible cigarette smoke on the respiratory system	10
Identification of key neuronal mechanisms triggered by dimethyl fumarate in SH-SY5Y human neuroblastoma cells through a metabolomic approach	10
In silico prediction of the interaction of legacy and novel per- and poly-fluoroalkyl substances (PFAS) with selected human transporters and of their possible accumulation in the human body	10
Targeting gut microbiota for immunotherapy of diseases	10
Human metabolism and excretion kinetics of benzotriazole UV stabilizer UV-327 after single oral administration	10
Non-clinical immunogenicity, biodistribution and toxicology evaluation of a chimpanzee adenovirus-based COVID-19 vaccine in rat and rhesus macaque	10
The “EU chemicals strategy for sustainability” questions regulatory toxicology as we know it: is it all rooted in sound scientific evidence?	10
Excavatolide C/cisplatin combination induces antiproliferation and drives apoptosis and DNA damage in bladder cancer cells	10
Investigating the in vitro steatotic mixture effects of similarly and dissimilarly acting test compounds using an adverse outcome pathway-based approach	9
Organoid-based 3D in vitro microphysiological systems as alternatives to animal experimentation for preclinical and clinical research	9
Potential of the zebrafish (Danio rerio) embryo test to discriminate between chemicals of similar molecular structure—a study with valproic acid and 14 of its analogues	9
Influence of deoxynivalenol-contaminated feed on the immune response of pigs after PRRSV vaccination and infection	9
Genetic variants of SOS2, MAP2K1 and RASGRF2 in the RAS pathway genes predict survival of HBV-related hepatocellular carcinoma patients	9
Interactions between polycyclic aromatic hydrocarbons and genetic variants in the cGAS–STING pathway affect the risk of colorectal cancer	9
Molecular signatures of angiogenesis inhibitors: a single-embryo untargeted metabolomics approach in zebrafish	9
A novel regQTL-SNP and the risk of lung cancer: a multi-dimensional study	9
The potential effects of HECTD4 variants on fasting glucose and triglyceride levels in relation to prevalence of type 2 diabetes based on alcohol intake	9
Simulations of radioiodine exposure and protective thyroid blocking in a new biokinetic model of the mother–fetus unit at different pregnancy ages	9
Thalidomide-induced limb malformations: an update and reevaluation	9
Kinetically-derived maximal dose (KMD) confirms lack of human relevance for high-dose effects of octamethylcyclotetrasiloxane (D4)	9
The relevance of acid sphingomyelinase as a potential target for therapeutic intervention in hepatic disorders: current scenario and anticipated trends	9
The functions and regulation of heat shock proteins; key orchestrators of proteostasis and the heat shock response	9
Interaction of the chemotherapeutic agent oxaliplatin and the tyrosine kinase inhibitor dasatinib with the organic cation transporter 2	9