Archives of Toxicology

Article	Citations
Cardiovascular responses of adult male Sprague–Dawley rats following acute organophosphate intoxication and post-exposure treatment with midazolam with or without allopregnanolone	488
Characterization of pathological changes in the olfactory system of mice exposed to methylmercury	149
Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models	145
Dopaminergic and serotonergic changes in rabbit fetal brain upon repeated gestational exposure to diesel engine exhaust	121
Pharmacogenetics in early drug development for non-alcoholic steatohepatitis: missed chances and future opportunities	115
Discovery of the Alternaria mycotoxins alterperylenol and altertoxin I as novel immunosuppressive and antiestrogenic compounds in vitro	96
Heavy metals: toxicity and human health effects	87
Hypertension toxicity of VEGFR-TKIs in cancer treatment: incidence, mechanisms, and management strategies	80
Minimum information for reporting on the TEER (trans-epithelial/endothelial electrical resistance) assay (MIRTA)	80
Establishment of a human 3D in vitro liver-bone model as a potential system for drug toxicity screening	68
Metabolic dysfunction-associated steatotic liver disease-induced changes in the antioxidant system: a review	66
Microarray analysis of gene expression in lung tissues of indium-exposed rats: possible roles of S100 proteins in lung diseases	63
Registration status of skin sensitisation data derived from the Local Lymph Node Assay (LLNA): BrdU-ELISA in REACH	61
Response to Dr. Reutova regarding the Letter to the Editor titled ‘What are the criteria and conditions for performing the micronucleus assay in oral exfoliated cells from children continuously expose	61
Thifluzamide exposure induced neuro-endocrine disrupting effects in zebrafish (Danio rerio)	60
Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity	53
A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe	53
Activation of (un)regulated cell death as a new perspective for bispyridinium and imidazolium oximes	52
Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids	51
Involvement of per- and polyfluoroalkyl compounds in tumor development	49
A novel approach to calculating the kinetically derived maximum dose	49
Cannabidiol disrupts apoptosis, autophagy and invasion processes of placental trophoblasts	48
Genetic variations in the CTLA-4 immune checkpoint pathway are associated with colon cancer risk, prognosis, and immune infiltration via regulation of IQCB1 expression	47
Developing urinary pyrrole–amino acid adducts as non-invasive biomarkers for identifying pyrrolizidine alkaloids-induced liver injury in human	47
Female offspring of mice perinatally exposed to benzophenone-3 showed early subfertility linked to a poor oocyte stockpile	46

The estimation of acute oral toxicity (LD50) of G-series organophosphorus-based chemical warfare agents using quantitative and qualitative toxicology in silico methods	46
The Bach1/HO-1 pathway regulates oxidative stress and contributes to ferroptosis in doxorubicin-induced cardiomyopathy in H9c2 cells and mice	45
Cytogenotoxicity and inflammatory response in liver of rats exposed to different doses of cannabis nano emulsions	44
Toxicokinetics of plasmatic VX in a swine model: comparison of a simple enzymatic titration method with a mass spectrometry method	43
Developmental brain lipidomics is influenced by postnatal chlorpyrifos exposure and APOE genetic background in mice	43
Comparison of comet-based approaches to assess base excision repair	42
The diarrhetic shellfish-poisoning toxin, okadaic acid, provokes gastropathy, dysbiosis and susceptibility to bacterial infection in a non-rodent bioassay, Galleria mellonella	42
US regulations to curb alleged cancer causes are ineffectual and compromised by scientific, constitutional and ethical violations	40
Bisphenol A and its analogues: from their occurrence in foodstuffs marketed in Europe to improved monitoring strategies—a review of published literature from 2018 to 2023	38
Connexins may play a critical role in cigarette smoke-induced pulmonary hypertension	37
Novel insight into mechanisms for ATR activation by chromatin structures	37
Reply to the opinion paper “The EU chemicals strategy for sustainability: an opportunity to develop new approaches for hazard assessment” by Scholz et al.	36
Interplay between proteasome function and inflammatory responses in e-cig vapor condensate-challenged lung epithelial cells	34
Use of innovative, cross-disciplinary in vitro, in silico and in vivo approaches to characterize the metabolism of chloro-alpha-pyrrolidinovalerophenone (4-Cl-PVP)	33
In vitro effects of the endocrine disruptor p,p′DDT on human choriogonadotropin/luteinizing hormone receptor signalling	33
Metabolism of alcohol ethoxylates (AEs) in rat, hamster, and human hepatocytes and liver S9: a pilot study for metabolic stability, metabolic pathway, and metabolites identification in vitro and in si	32
Species differences and human relevance of the toxicity of 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors and a new approach method in vitro for investigation	32
Sirtuins as molecular targets, mediators, and protective agents in metal-induced toxicity	31
Mechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition	31
The role of hypoxia-inducible factor 1 alpha (HIF-1α) modulation in heavy metal toxicity	31
Systematic evaluation of high-throughput PBK modelling strategies for the prediction of intravenous and oral pharmacokinetics in humans	31
A modular strategy for the testing and assessment of non-genotoxic carcinogens	31
The entactogen 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) as a treatment aid in psychotherapy and its safety concerns	31
Avicenna’s clinical toxicology approach and beneficial materia medica against oral poisoning	30
Molecular insights into the pathophysiology of doxorubicin-induced cardiotoxicity: a graphical representation	29
Carbon nanotubes conjugated with cisplatin activate different apoptosis signaling pathways in 2D and 3D-spheroid triple-negative breast cancer cell cultures: a comparative study	29
Chicken heterophils extracellular traps act as early effectors against cyclopiazonic acid dependent upon NADPH oxidase, ROS and glycolysis	28
Towards the mechanism of spermatotoxicity of p-tert-butyl-alpha-methylhydrocinnamic aldehyde: inhibition of late stage ex-vivo spermatogenesis in rat seminiferous tubule cultures by para-tert-butyl- b	28
Mouse innate-like B-1 lymphocytes promote inhaled particle-induced in vitro granuloma formation and inflammation in conjunction with macrophages	27
Neonatal opioid toxicity: opioid withdrawal (abstinence) syndrome with emphasis on pharmacogenomics and respiratory depression	27
Influence of deoxynivalenol and zearalenone on the immunohistochemical expression of oestrogen receptors and liver enzyme genes in vivo in prepubertal gilts	27
Effects of postnatal exposure to tetrabromobisphenol A on testis development in mice and early key events	27
SIRT3/GLUT4 signaling activation by metformin protect against cisplatin-induced ototoxicity in vitro	26
Assessing the role of the gut microbiome in methylmercury demethylation and elimination in humans and gnotobiotic mice	26
Reply to the opinion paper “The impact of stress on rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide: some theoretical concepts for scientific debate” by Silva et al.	26
A comparison of thyroidal protection by iodine and perchlorate against radioiodine exposure in Caucasians and Japanese	25
Role of miR-24-3p and miR-146a-5p in dendritic cells’ maturation process induced by contact sensitizers	25
Aryl hydrocarbon receptor (AHR) functions in infectious and sterile inflammation and NAD+-dependent metabolic adaptation	25
Impact of endocrine disruptors on peripheral blood mononuclear cells in vitro: role of gender	25
Prothioconazole induces cell cycle arrest by up-regulation of EIF4EBP1 in extravillous trophoblast cells	24
Methanol-induced optic neuropathy: a still-present problem	24
Intestinal and hepatic effects of iron oxide nanoparticles	23
N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances	23
Orphan nuclear receptor ERRγ regulates hepatic TGF-β2 expression and fibrogenic response in CCl4-induced acute liver injury	23
Structure-based virtual screening of CYP1A1 inhibitors: towards rapid tier-one assessment of potential developmental toxicants	23
The tyrosine kinase inhibitor LPM4870108 impairs learning and memory and induces transcriptomic and gene‑specific DNA methylation changes in rats	23
Mystery of methamphetamine-induced autophagosome accumulation in hippocampal neurons: loss of syntaxin 17 in defects of dynein–dynactin driving and autophagosome–late endosome/lysosome fusion	22
Cysteine conjugates of acetaminophen and p-aminophenol are potent inducers of cellular impairment in human proximal tubular kidney HK-2 cells	22
Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney	21
Hepatic metabolism of chlorinated derivatives of bisphenol A (ClxBPA) and interspecies differences between rats and humans	21

Impaired intestinal stem cell activity in ETEC infection: enterotoxins, cyclic nucleotides, and Wnt signaling	21
In vitro and in vivo protective potential of quercetin-3-glucuronide against lipopolysaccharide-induced pulmonary injury through dual activation of nuclear factor-erythroid 2 related factor 2 and auto	21
Androgenic properties of the dietary supplement 5α-hydroxy-laxogenin	21
Vascular endothelial dysfunction induced by 3-bromofluoranthene via MAPK-mediated-NFκB pro-inflammatory pathway and intracellular ROS generation	21
In vitro modeling of liver fibrosis in 3D microtissues using scalable micropatterning system	21
Role of hepcidin in oxidative stress and cell death of cultured mouse renal collecting duct cells: protection against iron and sensitization to cadmium	20
Feeding Brassica vegetables to rats leads to the formation of characteristic DNA adducts (from 1-methoxy-3-indolylmethyl glucosinolate) in many tissues	20
Rhazes's methodology in the science of toxicology	19
TRPM7 restrains plasmin activity and promotes transforming growth factor-β1 signaling in primary human lung fibroblasts	19
Opinion: A serious issue with the standardization of the adenovirus-based COVID-19 vaccines?	19
In vitro human cell-based TTR-TRβ CALUX assay indicates thyroid hormone transport disruption of short-chain, medium-chain, and long-chain chlorinated paraffins	19
Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds—a hypo	19
rVSV-ΔG-SARS-CoV-2-S vaccine: repeated intramuscular (IM) toxicity, local tolerance, immunogenicity and biodistribution study in NZW rabbits	19
Altered metabolic pathways elucidated via untargeted in vivo toxicometabolomics in rat urine and plasma samples collected after controlled application of a human equivalent amphetamine dose	19
PBTK model-based analysis of CYP3A4 induction and the toxicokinetics of the pyrrolizidine alkaloid retrorsine in man	18
The fungicide propiconazole induces hepatic steatosis and activates PXR in a mouse model of diet-induced obesity	18
New aspects in snake venom toxicology	18
Hepatoprotective effects of phytochemicals and plant extracts against chemotherapy-induced liver damage in animal models: a systematic review	18
Exposure to the mycotoxin deoxynivalenol reduces the transport of conjugated bile acids by intestinal Caco-2 cells	18
The EU chemicals strategy for sustainability: in support of the BfR position	18
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity	17
Paternal lipopolysaccharide exposure induced intrauterine growth restriction via the inactivation of placental MEST/PI3K/AKT pathway in mice	17
Drug-induced hepatic sinusoidal obstruction syndrome: current advances and future perspectives	17
Strategies for enhanced bioavailability of oxime reactivators in the central nervous system	17
Effects of co-formulants on the absorption and secretion of active substances in plant protection products in vitro	17
OCT1-dependent uptake of structurally diverse pyrrolizidine alkaloids in human liver cells is crucial for their genotoxic and cytotoxic effects	17
Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450s	17
Chronic oral exposure to low-concentration fumonisin B2 significantly exacerbates the inflammatory responses of allergies in mice via inhibition of IL-10 release by regulatory T cells in gut-associate	17
The Janus face of uranium in toxicology	17
A framework for establishing scientific confidence in new approach methodologies	17
Replacement of animal testing by integrated approaches to testing and assessment (IATA): a call for in vivitrosi	17
Differential impact of JUUL flavors on pulmonary immune modulation and oxidative stress responses in male and female mice	16
Evaluation of functional candidate biomarkers of non-genotoxic hepatocarcinogenicity in human liver spheroid co-cultures	16
Carbon monoxide-triggered health effects: the important role of the inflammasome and its possible crosstalk with autophagy and exosomes	16
Mechanistic perspectives on differential mitochondrial-based neuroprotective effects of several carnitine forms in Alzheimer’s disease in vitro model	16
Exposure limits for indoor volatile substances concerning the general population: The role of population-based differences in sensory irritation of the eyes and airways for assessment factors	16
Multi-omics bioactivity profile-based chemical grouping and read-across: a case study with Daphnia magna and azo dyes	16
Cell–cell contacts prevent t-BuOOH-triggered ferroptosis and cellular damage in vitro by regulation of intracellular calcium	16
Cannabidivarin and cannabigerol induce unfolded protein response and angiogenesis dysregulation in placental trophoblast HTR-8/SVneo cells	16
The IL-1 promoter-driven luciferase reporter cell line THP-G1b can efficiently predict skin-sensitising chemicals	16
From hazard to risk prioritization: a case study to predict drug-induced cholestasis using physiologically based kinetic modeling	16
Medaka embryos as a model for metabolism of anabolic steroids	16
A multi-biomarker micronucleus assay using imaging flow cytometry	16
Molecular mechanisms of environmental pollutant-induced cartilage damage: from developmental disorders to osteoarthritis	16
A multi-omics approach to elucidate okadaic acid-induced changes in human HepaRG hepatocarcinoma cells	16
Investigating the applicability domain of the hiPSC-based PluriLum assay: an embryotoxicity assessment of chemicals and drugs	16
Oral nicotine pouches with an aftertaste? Part 1: screening and initial toxicological assessment of flavorings and other ingredients	15
The effect of alkyl substitution on the oxidative metabolism and mutagenicity of phenanthrene	15
Optimized methods for measuring competitive binding of chemical substances to thyroid hormone distributor proteins transthyretin and thyroxine binding globulin	15
The food-borne carcinogenic 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) disrupts circadian rhythms and ameliorated by pterostilbene (PSB) in Caenorhabditis elegans	15
Elevated blood-ethanol concentration promotes reduction of aliphatic ketones (acetone and ethyl methyl ketone) to secondary alcohols along with slower oxidation to aliphatic diols	15
Effects of novel flame retardants tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) and triphenyl phosphate (TPhP) on function and homeostasis in human and rat pancreatic beta-cell lines	15
Trends in research on advanced glycation end products (AGEs)	15
Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh	15
Arylacetamide deacetylase regulates hepatic iron homeostasis to protect against carbon tetrachloride-induced ferroptosis	15
Effects of chronic insecticide exposure on neuronal network development in vitro in rat cortical cultures	15
Single-cell RNA sequencing to reveal non-parenchymal cell heterogeneity and immune network of acetaminophen-induced liver injury in mice	14
In silico analysis decodes transthyretin (TTR) binding and thyroid disrupting effects of per- and polyfluoroalkyl substances (PFAS)	14
Comparative case study on NAMs: towards enhancing specific target organ toxicity analysis	14
Environmental barium: potential exposure and health-hazards	14
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging	14
Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice	14
In vitro assessment of thyroid peroxidase inhibition by chemical exposure: comparison of cell models and detection methods	14
Grouping of chemicals for safety assessment: the importance of toxicokinetic properties of salicylate esters	14
Monitoring of per- and polyfluoroalkyl substances (PFAS) in human blood samples collected in three regions with known PFAS releases in the environment and three control regions in South Germany	14
Contribution to the ongoing discussion on fluoride toxicity	14
Non-invasive in vitro NAM for the detection of reversible and irreversible eye damage after chemical exposure for GHS classification purposes (ImAi)	13
A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS)	13
CYP2E1 in 1,4-dioxane metabolism and liver toxicity: insights from CYP2E1 knockout mice study	13
Are the current commercially available oximes capable of reactivating acetylcholinesterase inhibited by the nerve agents of the A-series?	13
Scientific discrepancies in European regulatory proposals on endocrine disruptors—REACH regulation quo vadis?	13
Basic concepts of mixture toxicity and relevance for risk evaluation and regulation	13
Toxicokinetics of 2-ethylhexyl salicylate (EHS) and its seven metabolites in humans after controlled single dermal exposure to EHS	13
Titanium dioxide nanoparticles: revealing the mechanisms underlying hepatotoxicity and effects in the gut microbiota	13
Exposure of intestinal explants to NX, but not to DON, enriches the secretome in mitochondrial proteins	13
Mammalian toxicity of trifluoroacetate and assessment of human health risks due to environmental exposures	13
Physiologically-based pharmacokinetic model for evaluating gender-specific exposures of N-nitrosodimethylamine (NDMA)	13
Synthesis and in vitro assessment of the reactivation profile of clinically available oximes on the acetylcholinesterase model inhibited by A-230 nerve agent surrogate	12
Gasdermin D membrane pores orchestrate IL-1α secretion from necrotic macrophages after NFS-rich silica exposure	12
Induction of clastogenesis and gene mutations by carbamazepine (at its therapeutically effective serum levels) in mammalian cells and the dependence on human CYP2B6 enzyme activity	12

Ferroptosis as a mechanism of non-ferrous metal toxicity	12
Progress in protecting vestibular hair cells	12
Nitrofurantoin-induced liver injury: long-term follow-up in two prospective DILI registries	12
Functional alterations by a subgroup of neonicotinoid pesticides in human dopaminergic neurons	12
Unraveling the AKT/ERK cascade and its role in Parkinson disease	12
Immunomodulation and exposure to per- and polyfluoroalkyl substances: an overview of the current evidence from animal and human studies	12
Screening for ferroptosis genes related to endometrial carcinoma and predicting of targeted drugs based on bioinformatics	12
Cancer drug resistance induced by EMT: novel therapeutic strategies	12
Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose	12
The EU chemicals strategy for sustainability: critical reflections on proposed regulatory changes for endocrine disruptors and mixture toxicity	12
Issue analysis: key characteristics approach for identifying endocrine disruptors	12
Characterization of drug-induced liver injury associated with drug reaction with eosinophilia and systemic symptoms in two prospective DILI registries	12
Morphological alterations in C57BL/6 mouse intestinal organoids as a tool for predicting chemical-induced toxicity	12
Accumulation of chlorinated paraffins in adipocytes is determined by cellular lipid content and chlorination level	11
Multi-organ developmental toxicity and its characteristics in fetal mice induced by dexamethasone at different doses, stages, and courses during pregnancy	11
Infections at the nexus of metabolic-associated fatty liver disease	11
Short-term repeated oral intake of low dose cannabidiol: effects on liver enzyme activity and creatinine concentration during intense exercise	11
Chronic bisphenol A exposure triggers visual perception dysfunction through impoverished neuronal coding ability in the primary visual cortex	11
Correction to: Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data	11
Neurotoxicity evoked by organophosphates and available countermeasures	11
Author Correction: Hazard characterization of Alternaria toxins to identify data gaps and improve risk assessment for human health	11
Systems analysis of miRNA biomarkers to inform drug safety	11
Effects of low concentrations of ozone gas exposure on percutaneous oxygen saturation and inflammatory responses in a mouse model of Dermatophagoides farinae-induced asthma	11
Evaluation of the cyto- and genotoxicity of two types of cellulose nanomaterials using human intestinal cells and in vitro digestion simulation	11
Development of a transcriptome-based determination of innate immune suppressor (TDIS) assay as an in vitro test for immunotoxicity	11
Effects of carbon black particles on human monocyte-derived macrophages: type-dependent pro-inflammatory activation in vitro	11
Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells	11
Dynamics in zebrafish development define transcriptomic specificity after angiogenesis inhibitor exposure	11
Disentangling the role of selenium in antagonizing the toxicity of arsenic and cadmium	11
Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers	11
Metabolism-mediated cytotoxicity and genotoxicity of pyrrolizidine alkaloids	11
miR-451a and miR-486-5p: biomarkers for benzene-induced hematotoxicity	11
Proteomic profiling of murine biliary-derived hepatic organoids and their capacity for drug disposition, bioactivation and detoxification	11
Sepsis-induced cardiomyopathy: understanding pathophysiology and clinical implications	11
Combined use of multiparametric high-content-screening and in vitro circadian reporter assays in neurotoxicity evaluation	11
Estimating the reduction in US mortality if cigarettes were largely replaced by e-cigarettes	11
Metabolism and interactions of Ivermectin with human cytochrome P450 enzymes and drug transporters, possible adverse and toxic effects	10
Effects of drug-drug interactions and CYP3A4 variants on alectinib metabolism	10
Apelin-13 protects against cisplatin-induced ototoxicity by inhibiting apoptosis and regulating STAT1 and STAT3	10
Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validation	10
Multi-omics analysis reveals metabolism of okadaic acid in gut lumen of rat	10
Krebs cycle: activators, inhibitors and their roles in the modulation of carcinogenesis	10
Laser vs. thermal treatments of green pigment PG36: coincidence and toxicity of processes	10
New data on the metabolism of chloromethylisothiazolinone and methylisothiazolinone in human volunteers after oral dosage: excretion kinetics of a urinary mercapturic acid metabolite (“M-12”)	10
Repeated-dose toxicity and toxicokinetic study of isobutylparaben in rats subcutaneously treated for 13 weeks	10
Dapagliflozin protects against doxorubicin-induced cardiotoxicity by restoring STAT3	10
Identification, synthesis and quantification of eutylone consumption markers in a chemsex context	10
A fast and reliable method for monitoring genomic instability in the model organism Caenorhabditis elegans	10
Toxicokinetics of praseodymium and cerium administered as chloride salts in Sprague–Dawley rats: impacts of the dose and of co-exposure with additional rare earth elements	10
The evaluation of skin sensitization potential of the UVCB substance diisopentyl phthalate by in silico and in vitro methods	10
Cytotoxicity of Prymnesium parvum extracts and prymnesin analogs on epithelial fish gill cells RTgill-W1 and the human colon cell line HCEC-1CT	9
One-step extraction and determination of 513 psychoactive substances, drugs, and their metabolites from hair by LC–MS/MS	9
Toxicological and pharmacological characterization of novel cinnamylpiperazine synthetic opioids in humans and in vitro including 2-methyl AP-237 and AP-238	9
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment	9
Ensemble machine learning to evaluate the in vivo acute oral toxicity and in vitro human acetylcholinesterase inhibitory activity of organophosphates	9
Guidance for statistical design and analysis of toxicological dose–response experiments, based on a comprehensive literature review	9
Application of physiologically based (PBK) modeling to quantify the effect of the antibiotic tobramycin on bile acid levels in human plasma	9
Targeting erythrocyte-mediated hypoxia to alleviate lung injury induced by pyrrolizidine alkaloids	9
In vitro models to detect in vivo bile acid changes induced by antibiotics	9
Transforming toxins into treatments: the revolutionary role of α-amanitin in cancer therapy	9
iNKT17 cells play a pathogenic role in ethinylestradiol-induced cholestatic hepatotoxicity	9
In vitro metabolism of helenalin and its inhibitory effect on human cytochrome P450 activity	9
Toxicokinetics of homosalate in humans after dermal application: applicability of oral-route data for exposure assessment by human biomonitoring	9
Evolution of hormesis research: a bibliometric analysis	9
Systemic effects and impact on the gut microbiota upon subacute oral exposure to silver acetate in rats	9
Future in the past: paternal reprogramming of offspring phenotype and the epigenetic mechanisms	9
The interactions of subcellular organelles in pulmonary fibrosis induced by carbon black nanoparticles: a comprehensive review	9
Assessment of the potential vaping-related exposure to carbonyls and epoxides using stable isotope-labeled precursors in the e-liquid	9
Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants	9
Newly discovered letter: why Muller failed to cite the negative mouse mutation findings of Snell, preserving his chances to receive the Nobel Prize	9
In vitro to in vivo extrapolation and high-content imaging for simultaneous characterization of chemically induced liver steatosis and markers of hepatotoxicity	9
Biotransformation and toxicokinetics of 2-phenoxyethanol after oral exposure in humans: a volunteer study	9
Compromised blood–bile barrier after acetaminophen overdose	9
Quality of reporting animal studies	8
Systemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed?	8
Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell models	8
Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis	8
How to avoid misinterpretation of dual reporter gene assay data affected by cell damage	8
Cell survival after DNA damage in the comet assay	8
N6-methyladenosine reader YTHDC2 and eraser FTO may determine hepatocellular carcinoma prognoses after transarterial chemoembolization	8
Antineoplastic therapy affects the in vitro phenotype and functionality of healthy human bone marrow-derived mesenchymal stromal cells	8
Functional variants of RPS6KB1 and PIK3R1 in the autophagy pathway genes and risk of bladder cancer	8
The role of cellular senescence in neurodegenerative diseases	8
Mouse precision-cut liver slices as an ex vivo model to study drug-induced cholestasis	8
Integrated data from intravital imaging and HPLC–MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats	8
Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation	8
Comparative metabolism of aflatoxin B1 in mouse, rat and human primary hepatocytes using HPLC–MS/MS	8
Yttrium chloride-induced cytotoxicity and DNA damage response via ROS generation and inhibition of Nrf2/PPARγ pathways in H9c2 cardiomyocytes	8
Modernizing persistence–bioaccumulation–toxicity (PBT) assessment with high throughput animal-free methods	8
The role of ferroptosis in cardio-oncology	8
Sex differences in the tumor promoting effects of tobacco smoke in a cRaf transgenic lung cancer disease model	8
Impact of plastic-related compounds on the gene expression signature of HepG2 cells transfected with CYP3A4	8
Considerations for the optimization of in vitro models of chloropicrin toxicity	8
The role of genetic polymorphisms for inducing genotoxicity in workers occupationally exposed to benzene: a systematic review	8
In silico and in vitro metabolism studies of the new synthetic opiate AP-237 (bucinnazine) using bioinformatics tools	8