Archives of Toxicology

Article	Citations
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging	313
Toxicology and pharmacology of synthetic organoselenium compounds: an update	140
Cancer drug resistance induced by EMT: novel therapeutic strategies	116
ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis	97
A framework for establishing scientific confidence in new approach methodologies	87
Environmental barium: potential exposure and health-hazards	86
Prediction reliability of QSAR models: an overview of various validation tools	73
An updated review on synthetic cathinones	68
The functions and regulation of heat shock proteins; key orchestrators of proteostasis and the heat shock response	65
Toxicities of opioid analgesics: respiratory depression, histamine release, hemodynamic changes, hypersensitivity, serotonin toxicity	63
Current EU regulatory requirements for the assessment of chemicals and cosmetic products: challenges and opportunities for introducing new approach methodologies	61
Cadmium induces renal inflammation by activating the NLRP3 inflammasome through ROS/MAPK/NF-κB pathway in vitro and in vivo	61
Cross-species analysis of hepatic cytochrome P450 and transport protein expression	60
Artificial intelligence and machine learning disciplines with the potential to improve the nanotoxicology and nanomedicine fields: a comprehensive review	56
Antidepressants- and antipsychotics-induced hepatotoxicity	55
Toxicokinetics and metabolism of deoxynivalenol in animals and humans	52
Krebs cycle: activators, inhibitors and their roles in the modulation of carcinogenesis	52
Acute, reproductive, and developmental toxicity of essential oils assessed with alternative in vitro and in vivo systems	52
Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants	52
Prediction of oral hepatotoxic dose of natural products derived from traditional Chinese medicines based on SVM classifier and PBPK modeling	51
Human Family 1–4 cytochrome P450 enzymes involved in the metabolic activation of xenobiotic and physiological chemicals: an update	51
Hypoxia, oxidative stress, and immune evasion: a trinity of the trichothecenes T-2 toxin and deoxynivalenol (DON)	49
A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe	49
Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose	49
A framework for chemical safety assessment incorporating new approach methodologies within REACH	47

Molecular insights into the pathophysiology of doxorubicin-induced cardiotoxicity: a graphical representation	47
Origins, fate, and actions of methylated trivalent metabolites of inorganic arsenic: progress and prospects	46
Gadolinium: pharmacokinetics and toxicity in humans and laboratory animals following contrast agent administration	46
Functional alterations by a subgroup of neonicotinoid pesticides in human dopaminergic neurons	44
Dapagliflozin suppresses ER stress and protects doxorubicin-induced cardiotoxicity in breast cancer patients	44
3D bioprinting of complex tissues in vitro: state-of-the-art and future perspectives	43
Ferroptosis as a mechanism of non-ferrous metal toxicity	43
Mechanisms of deoxynivalenol-induced endocytosis and degradation of tight junction proteins in jejunal IPEC-J2 cells involve selective activation of the MAPK pathways	41
Methanol-induced optic neuropathy: a still-present problem	40
Nrf2 deficiency aggravates the kidney injury induced by subacute cadmium exposure in mice	39
Metabolism-mediated cytotoxicity and genotoxicity of pyrrolizidine alkaloids	38
Neonicotinoids: mechanisms of systemic toxicity based on oxidative stress-mitochondrial damage	38
Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling	37
Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis	37
Ochratoxin A induces nephrotoxicity in vitro and in vivo via pyroptosis	36
Toxicology and pharmacology of botulinum and tetanus neurotoxins: an update	35
Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole ‘nitazene’ synthetic opioid	33
Estimation of health risks associated with dietary cadmium exposure	33
The role of endogenous versus exogenous sources in the exposome of putative genotoxins and consequences for risk assessment	33
Fumonisin B1 alters global m6A RNA methylation and epigenetically regulates Keap1-Nrf2 signaling in human hepatoma (HepG2) cells	32
Kupffer cells regulate liver recovery through induction of chemokine receptor CXCR2 on hepatocytes after acetaminophen overdose in mice	32
Neurotoxicity and underlying cellular changes of 21 mitochondrial respiratory chain inhibitors	31
Nrf2: a main responsive element in cells to mycotoxin-induced toxicity	31
Cytochrome P450-dependent biotransformation capacities in embryonic, juvenile and adult stages of zebrafish (Danio rerio)—a state-of-the-art review	31
Pharmacology and toxicology of tannins	31
Implementing organ-on-chip in a next-generation risk assessment of chemicals: a review	31
Cytochrome P450 expression, induction and activity in human induced pluripotent stem cell-derived intestinal organoids and comparison with primary human intestinal epithelial cells and Caco-2 cells	30
In vitro human cell-based TTR-TRβ CALUX assay indicates thyroid hormone transport disruption of short-chain, medium-chain, and long-chain chlorinated paraffins	30
Effects of the food colorant carmoisine on zebrafish embryos at a wide range of concentrations	29
New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids	29
Metabolism and interactions of Ivermectin with human cytochrome P450 enzymes and drug transporters, possible adverse and toxic effects	29
Pharmacology and toxicology of eteplirsen and SRP-5051 for DMD exon 51 skipping: an update	28
Electronic cigarette aerosols induce oxidative stress-dependent cell death and NF-κB mediated acute lung inflammation in mice	27
Neurotoxicity evoked by organophosphates and available countermeasures	27
Hepatotoxicity induced by nanomaterials: mechanisms and in vitro models	27
A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS)	27
Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes	27
Mechanisms of opioid-induced respiratory depression	26
Sacubitril/valsartan reduces endoplasmic reticulum stress in a rat model of doxorubicin-induced cardiotoxicity	26
Dynamic alteration in miRNA and mRNA expression profiles at different stages of chronic arsenic exposure-induced carcinogenesis in a human cell culture model of skin cancer	26
Understanding the molecular mechanisms of statin pleiotropic effects	26
Development and safety of PI3K inhibitors in cancer	26
Sirtuins as molecular targets, mediators, and protective agents in metal-induced toxicity	26
Recent progress of iPSC technology in cardiac diseases	25
The pro-radical hydrogen peroxide as a stable hydroxyl radical distributor: lessons from pancreatic beta cells	25
The “EU chemicals strategy for sustainability” questions regulatory toxicology as we know it: is it all rooted in sound scientific evidence?	25
A review of species differences in the control of, and response to, chemical-induced thyroid hormone perturbations leading to thyroid cancer	24
N6-methyladenosine reader YTHDC2 and eraser FTO may determine hepatocellular carcinoma prognoses after transarterial chemoembolization	24
A current perspective on snake venom composition and constituent protein families	24
Clinical application of pyrrole–hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans	24

Human metabolism and urinary excretion of seven neonicotinoids and neonicotinoid-like compounds after controlled oral dosages	23
Can seafood from marine sites of dumped World War relicts be eaten?	23
Replacement of animal testing by integrated approaches to testing and assessment (IATA): a call for in vivitrosi	23
Delayed administration of N-acetylcysteine blunts recovery after an acetaminophen overdose unlike 4-methylpyrazole	23
Chronic intestinal inflammation drives colorectal tumor formation triggered by dietary heme iron in vivo	22
Dapagliflozin protects against doxorubicin-induced cardiotoxicity by restoring STAT3	22
The application of cytokeratin-18 as a biomarker for drug-induced liver injury	21
Nephrotoxic antisense oligonucleotide SPC5001 induces kidney injury biomarkers in a proximal tubule-on-a-chip	21
First identification, chemical analysis and pharmacological characterization of N-piperidinyl etonitazene (etonitazepipne), a recent addition to the 2-benzylbenzimidazole opioid subclass	21
DMSO-free highly differentiated HepaRG spheroids for chronic toxicity, liver functions and genotoxicity studies	21
Polyphenols: a route from bioavailability to bioactivity addressing potential health benefits to tackle human chronic diseases	21
Effect of bisphenol A on the neurological system: a review update	20
A novel regQTL-SNP and the risk of lung cancer: a multi-dimensional study	20
Benzo[a]pyrene and Caenorhabditis elegans: defining the genotoxic potential in an organism lacking the classical CYP1A1 pathway	20
DNA methyltransferase- and histone deacetylase-mediated epigenetic alterations induced by low-level methylmercury exposure disrupt neuronal development	20
Diagnosing intake and rationalizing toxicities associated with 5F-MDMB-PINACA and 4F-MDMB-BINACA abuse	20
Principles of dose-setting in toxicology studies: the importance of kinetics for ensuring human safety	20
Deoxynivalenol induces caspase-3/GSDME-dependent pyroptosis and inflammation in mouse liver and HepaRG cells	19
A review on immunomodulatory effects of BPA analogues	19
Perfluoroalkyl substances (PFASs) are substrates of the renal human organic anion transporter 4 (OAT4)	19
Carbon monoxide-triggered health effects: the important role of the inflammasome and its possible crosstalk with autophagy and exosomes	19
Differences in P-glycoprotein activity in human and rodent blood–brain barrier assessed by mechanistic modelling	19
Validation of the in vitro comet assay for DNA cross-links and altered bases detection	19
Glyphosate exposure induces synaptic impairment in hippocampal neurons and cognitive deficits in developing rats	19
Cannabidiol disrupts apoptosis, autophagy and invasion processes of placental trophoblasts	19
Mapping DEHP to the adverse outcome pathway network for human female reproductive toxicity	19
Effect of cryopreservation on DNA damage and DNA repair activity in human blood samples in the comet assay	19
Genetic variants in m6A regulators are associated with gastric cancer risk	18
Ingestion of titanium dioxide nanoparticles: a definite health risk for consumers and their progeny	18
Cardiotoxicity of cyclophosphamide’s metabolites: an in vitro metabolomics approach in AC16 human cardiomyocytes	18
Identification of genetic variants in m6A modification genes associated with pancreatic cancer risk in the Chinese population	18
Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application	18
More than additive effects on liver triglyceride accumulation by combinations of steatotic and non-steatotic pesticides in HepaRG cells	18
Human neuronal signaling and communication assays to assess functional neurotoxicity	18
Roles of selected non-P450 human oxidoreductase enzymes in protective and toxic effects of chemicals: review and compilation of reactions	18
Inhibition of neurite outgrowth and enhanced effects compared to baseline toxicity in SH-SY5Y cells	18
The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment	18
Role of Ca2+ in healthy and pathologic cardiac function: from normal excitation–contraction coupling to mutations that cause inherited arrhythmia	17
Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model	17
Developments in high-resolution mass spectrometric analyses of new psychoactive substances	17
Genotoxicity assessment: opportunities, challenges and perspectives for quantitative evaluations of dose–response data	17
Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice	17
A review and assessment of cyanobacterial toxins as cardiovascular health hazards	17
Integration of data across toxicity endpoints for improved safety assessment of chemicals: the example of carcinogenicity assessment	17
Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages	17
Infections at the nexus of metabolic-associated fatty liver disease	16
The diarrhetic shellfish-poisoning toxin, okadaic acid, provokes gastropathy, dysbiosis and susceptibility to bacterial infection in a non-rodent bioassay, Galleria mellonella	16
Mechanistic perspectives on differential mitochondrial-based neuroprotective effects of several carnitine forms in Alzheimer’s disease in vitro model	16
Human metabolism and kinetics of the UV absorber 2-(2H-benzotriazol-2-yl)-4,6-di-tert-pentylphenol (UV 328) after oral administration	16
Identification and characterization of potent, selective, and efficacious inhibitors of human arylamine N-acetyltransferase 1	16
Inter-laboratory automation of the in vitro micronucleus assay using imaging flow cytometry and deep learning	16
Subcellular spatio-temporal intravital kinetics of aflatoxin B1 and ochratoxin A in liver and kidney	16
Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative d	16
Systems analysis of miRNA biomarkers to inform drug safety	16
Immunomodulation and exposure to per- and polyfluoroalkyl substances: an overview of the current evidence from animal and human studies	16
Differential impact of JUUL flavors on pulmonary immune modulation and oxidative stress responses in male and female mice	16
Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation	16
In silico, in vitro, and in vivo human metabolism of acetazolamide, a carbonic anhydrase inhibitor and common “diuretic and masking agent” in doping	16
Characterization of recent non-fentanyl synthetic opioids via three different in vitro µ-opioid receptor activation assays	15
Metabolic profiling as a powerful tool for the analysis of cellular alterations caused by 20 mycotoxins in HepG2 cells	15
Cell survival after DNA damage in the comet assay	15
Physiology-based toxicokinetic modelling of aluminium in rat and man	15
Impacts of bisphosphonates on the bone and its surrounding tissues: mechanistic insights into medication-related osteonecrosis of the jaw	15
The electrophysiological effects of cannabidiol on action potentials and transmembrane potassium currents in rabbit and dog cardiac ventricular preparations	15
Activation of autophagy triggers mitochondrial loss and changes acetylation profile relevant for mechanotransduction in bladder cancer cells	15
Recent research on Novichok	15
Effect of methylmercury on fetal neurobehavioral development: an overview of the possible mechanisms of toxicity and the neuroprotective effect of phytochemicals	14
Expanded high-throughput screening and chemotype-enrichment analysis of the phase II: e1k ToxCast library for human sodium-iodide symporter (NIS) inhibition	14
In vitro interactions of Alternaria mycotoxins, an emerging class of food contaminants, with the gut microbiota: a bidirectional relationship	14
Nitrofurantoin-induced liver injury: long-term follow-up in two prospective DILI registries	14
Nanoparticle-induced inflammation and fibrosis in ex vivo murine precision-cut liver slices and effects of nanoparticle exposure conditions	14
Quo vadis blood protein adductomics?	14
Ensemble machine learning to evaluate the in vivo acute oral toxicity and in vitro human acetylcholinesterase inhibitory activity of organophosphates	14
Impaired protein adduct removal following repeat administration of subtoxic doses of acetaminophen enhances liver injury in fed mice	14
Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71	14
Farnesoid X receptor (FXR) agonists induce hepatocellular apoptosis and impair hepatic functions via FXR/SHP pathway	14
Circular RNA circ_Cabin1 promotes DNA damage in multiple mouse organs via inhibition of non-homologous end-joining repair upon PM2.5 exposure	14
Assessment of multiple mycotoxin exposure and its association with food consumption: a human biomonitoring study in a pregnant cohort in rural Bangladesh	14
Intestinal and hepatic effects of iron oxide nanoparticles	14
Ascorbate: antioxidant and biochemical activities and their importance for in vitro models	13

Effects of co-formulants on the absorption and secretion of active substances in plant protection products in vitro	13
In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)	13
Mycotoxins and cellular senescence: the impact of oxidative stress, hypoxia, and immunosuppression	13
Sex-dependent dynamics of metabolism in primary mouse hepatocytes	13
Determination of in vitro hepatotoxic potencies of a series of perfluoroalkyl substances (PFASs) based on gene expression changes in HepaRG liver cells	13
Contribution to the ongoing discussion on fluoride toxicity	13
Towards better prediction of xenobiotic genotoxicity: CometChip technology coupled with a 3D model of HepaRG human liver cells	13
Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A	13
Exploring the dermotoxicity of the mycotoxin deoxynivalenol: combined morphologic and proteomic profiling of human epidermal cells reveals alteration of lipid biosynthesis machinery and membrane struc	13
Acute exposure to microcystin-LR induces hepatopancreas toxicity in the Chinese mitten crab (Eriocheir sinensis)	13
Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3	13
Pharmacokinetics and toxicity evaluation following oral exposure to bisphenol F	13
microRNAs signatures as potential biomarkers of structural cardiotoxicity in human-induced pluripotent stem-cell derived cardiomyocytes	12
Bothrops lanceolatus snake (Fer-de-lance) venom triggers inflammatory mediators’ storm in human blood	12
Case study: risk associated to wearing silver or graphene nanoparticle-coated facemasks for protection against COVID-19	12
Assessment of the exposure to polycyclic aromatic hydrocarbons in users of various tobacco/nicotine products by suitable urinary biomarkers	12
Alkylated epidermal creatine kinase as a biomarker for sulfur mustard exposure: comparison to adducts of albumin and DNA in an in vivo rat study	12
Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment	12
Deoxynivalenol induces apoptosis and autophagy in human prostate epithelial cells via PI3K/Akt signaling pathway	12
Effects of postnatal exposure to tetrabromobisphenol A on testis development in mice and early key events	12
Neurotoxicity of four frequently used nanoparticles: a systematic review to reveal the missing data	12
A human stem cell-derived test system for agents modifying neuronal N-methyl-d-aspartate-type glutamate receptor Ca2+-signalling	12
The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro	12
The BH3 mimetic (±) gossypol induces ROS-independent apoptosis and mitochondrial dysfunction in human A375 melanoma cells in vitro	12
Yttrium chloride-induced cytotoxicity and DNA damage response via ROS generation and inhibition of Nrf2/PPARγ pathways in H9c2 cardiomyocytes	12
Activation of (un)regulated cell death as a new perspective for bispyridinium and imidazolium oximes	12
In vitro effects of the endocrine disruptor p,p′DDT on human choriogonadotropin/luteinizing hormone receptor signalling	12
Urolithin A attenuates arsenic-induced gut barrier dysfunction	12
Precision cut lung slices: an ex vivo model for assessing the impact of immunomodulatory therapeutics on lung immune responses	12
Assessment of cochlear toxicity in response to chronic 3,3′-iminodipropionitrile in mice reveals early and reversible functional loss that precedes overt histopathology	12
Duplex sequencing provides detailed characterization of mutation frequencies and spectra in the bone marrow of MutaMouse males exposed to procarbazine hydrochloride	12
Recommendations on dose level selection for repeat dose toxicity studies	12
A-agents, misleadingly known as “Novichoks”: a narrative review	12
In silico analysis decodes transthyretin (TTR) binding and thyroid disrupting effects of per- and polyfluoroalkyl substances (PFAS)	12
Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism	12
A mixture of 13 pesticides, contaminants, and food additives below individual NOAELs produces histopathological and organ weight changes in rats	11
Genotoxicity and inflammatory potential of stainless steel welding fume particles: an in vitro study on standard vs Cr(VI)-reduced flux-cored wires and the role of released metals	11
T-2 toxin-induced intestinal damage with dysregulation of metabolism, redox homeostasis, inflammation, and apoptosis in chicks	11
Systems toxicology study reveals reduced impact of heated tobacco product aerosol extract relative to cigarette smoke on premature aging and exacerbation effects in aged aortic cells in vitro	11
Serotonin involvement in okadaic acid-induced diarrhoea in vivo	11
Assessment of the potential vaping-related exposure to carbonyls and epoxides using stable isotope-labeled precursors in the e-liquid	11
The effect of alkyl substitution on the oxidative metabolism and mutagenicity of phenanthrene	11
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity	11
Post-VX exposure treatment of rats with engineered phosphotriesterases	11
Kinetic time courses of inhaled silver nanoparticles in rats	11
Human risk assessment of di-isobutyl phthalate through the application of a developed physiologically based pharmacokinetic model of di-isobutyl phthalate and its major metabolite mono-isobutyl phthal	11
CRISPR-based DNA methylation editing of NNT rescues the cisplatin resistance of lung cancer cells by reducing autophagy	11
Human risk assessment of 4-n-nonylphenol (4-n-NP) using physiologically based pharmacokinetic (PBPK) modeling: analysis of gender exposure differences and application to exposure analysis related to l	11
Four decades of chemotherapy-induced cognitive dysfunction: comprehensive review of clinical, animal and in vitro studies, and insights of key initiating events	11
Toxicological and pharmacological characterization of novel cinnamylpiperazine synthetic opioids in humans and in vitro including 2-methyl AP-237 and AP-238	11
Are the current commercially available oximes capable of reactivating acetylcholinesterase inhibited by the nerve agents of the A-series?	11
Host genetics and gut microbiota cooperatively contribute to azoxymethane-induced acute toxicity in Collaborative Cross mice	11
Application of toxicology in silico methods for prediction of acute toxicity (LD50) for Novichoks	11
Association between lead exposure and DNA damage (genotoxicity): systematic review and meta-analysis	11
Spatiotemporal analysis of the UPR transition induced by methylmercury in the mouse brain	11
Development of versatile and potent monoquaternary reactivators of acetylcholinesterase	11
Particulate and drug-induced toxicity assessed in novel quadruple cell human primary hepatic disease models of steatosis and pre-fibrotic NASH	11
Development and validation of the TGx-HDACi transcriptomic biomarker to detect histone deacetylase inhibitors in human TK6 cells	11
The EU chemicals strategy for sustainability: critical reflections on proposed regulatory changes for endocrine disruptors and mixture toxicity	11
What do we currently know about Novichoks? The state of the art	10
TRPM7 restrains plasmin activity and promotes transforming growth factor-β1 signaling in primary human lung fibroblasts	10
Aryl hydrocarbon receptor (AHR) functions in infectious and sterile inflammation and NAD+-dependent metabolic adaptation	10
Serious liver injury induced by Nimesulide: an international collaborative study	10
Effects of low-dose bisphenol AF on mammal testis development via complex mechanisms: alterations are detectable in both infancy and adulthood	10
Expression of stem cell markers as useful complementary factors in the early detection of urinary bladder carcinogens by immunohistochemistry for γ-H2AX	10
Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450s	10
Research for type 2 diabetes mellitus in endemic arsenism areas in central China: role of low level of arsenic exposure and KEAP1 rs11545829 polymorphism	10
Coenzyme Q0 defeats NLRP3-mediated inflammation, EMT/metastasis, and Warburg effects by inhibiting HIF-1α expression in human triple-negative breast cancer cells	10
Mammalian toxicity of trifluoroacetate and assessment of human health risks due to environmental exposures	10
Impaired intestinal stem cell activity in ETEC infection: enterotoxins, cyclic nucleotides, and Wnt signaling	10
Transcriptomics analysis of hepatotoxicity induced by the pesticides imazalil, thiacloprid and clothianidin alone or in binary mixtures in a 28-day study in female Wistar rats	10
Catalytic activity and stereoselectivity of engineered phosphotriesterases towards structurally different nerve agents in vitro	10
Oxidative-stress and long-term hepatotoxicity: comparative study in Upcyte human hepatocytes and hepaRG cells	9
Toxic effect of light on oocyte and pre-implantation embryo: a systematic review	9
Role of microRNAs in response to cadmium chloride in pancreatic ductal adenocarcinoma	9
LncRNA H19 modulated by miR-146b-3p/miR-1539-mediated allelic regulation in transarterial chemoembolization of hepatocellular carcinoma	9
Opioid toxicity: histamine, hypersensitivity, and MRGPRX2	9
Proactive therapeutic drug monitoring of vincristine in pediatric and adult cancer patients: current supporting evidence and future efforts	9
Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation	9
Chicken heterophils extracellular traps act as early effectors against cyclopiazonic acid dependent upon NADPH oxidase, ROS and glycolysis	9
Circular RNA circNIPBL promotes NNK-induced DNA damage in bronchial epithelial cells via the base excision repair pathway	9
Mechanism and treatment of α-amanitin poisoning	9
Determinants and mechanisms of inorganic nanoparticle translocation across mammalian biological barriers	9
Inhalation of hydrogenated vegetable oil combustion exhaust and genotoxicity responses in humans	9
Repetitive diacetyl vapor exposure promotes ubiquitin proteasome stress and precedes bronchiolitis obliterans pathology	9
Chlordecone: development of a physiologically based pharmacokinetic tool to support human health risks assessments	9
Notch1-mediated inflammation is associated with endothelial dysfunction in human brain microvascular endothelial cells upon particulate matter exposure	9
Basic concepts of mixture toxicity and relevance for risk evaluation and regulation	9
Renal hypoxia–HIF–PHD–EPO signaling in transition metal nephrotoxicity: friend or foe?	9
Inflammation as common link to progressive neurological diseases	9
Artificial intelligence (AI)—it’s the end of the tox as we know it (and I feel fine)*	9
The influence of the long-term chemical activation of the nuclear receptor pregnane X receptor (PXR) on liver carcinogenesis in mice	9
The 28 + 28 day design is an effective sampling time for analyzing mutant frequencies in rapidly proliferating tissues of MutaMouse animals	9
Physiologically based kinetic modelling based prediction of in vivo rat and human acetylcholinesterase (AChE) inhibition upon exposure to diazinon	9
The role of hypoxia-inducible factor 1 alpha (HIF-1α) modulation in heavy metal toxicity	9