OOIR: Observatory of International Research

Papers

(The H4-Index of Archives of Toxicology is 37. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging	313
Toxicology and pharmacology of synthetic organoselenium compounds: an update	140
Cancer drug resistance induced by EMT: novel therapeutic strategies	116
ROS-induced lipid peroxidation modulates cell death outcome: mechanisms behind apoptosis, autophagy, and ferroptosis	97
A framework for establishing scientific confidence in new approach methodologies	87
Environmental barium: potential exposure and health-hazards	86
Prediction reliability of QSAR models: an overview of various validation tools	73
An updated review on synthetic cathinones	68
The functions and regulation of heat shock proteins; key orchestrators of proteostasis and the heat shock response	65
Toxicities of opioid analgesics: respiratory depression, histamine release, hemodynamic changes, hypersensitivity, serotonin toxicity	63
Current EU regulatory requirements for the assessment of chemicals and cosmetic products: challenges and opportunities for introducing new approach methodologies	61
Cadmium induces renal inflammation by activating the NLRP3 inflammasome through ROS/MAPK/NF-κB pathway in vitro and in vivo	61
Cross-species analysis of hepatic cytochrome P450 and transport protein expression	60
Artificial intelligence and machine learning disciplines with the potential to improve the nanotoxicology and nanomedicine fields: a comprehensive review	56
Antidepressants- and antipsychotics-induced hepatotoxicity	55
Krebs cycle: activators, inhibitors and their roles in the modulation of carcinogenesis	52
Acute, reproductive, and developmental toxicity of essential oils assessed with alternative in vitro and in vivo systems	52
Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants	52
Toxicokinetics and metabolism of deoxynivalenol in animals and humans	52
Human Family 1–4 cytochrome P450 enzymes involved in the metabolic activation of xenobiotic and physiological chemicals: an update	51
Prediction of oral hepatotoxic dose of natural products derived from traditional Chinese medicines based on SVM classifier and PBPK modeling	51
A walk in the PARC: developing and implementing 21st century chemical risk assessment in Europe	49
Comparing N-acetylcysteine and 4-methylpyrazole as antidotes for acetaminophen overdose	49
Hypoxia, oxidative stress, and immune evasion: a trinity of the trichothecenes T-2 toxin and deoxynivalenol (DON)	49
A framework for chemical safety assessment incorporating new approach methodologies within REACH	47

Molecular insights into the pathophysiology of doxorubicin-induced cardiotoxicity: a graphical representation	47
Gadolinium: pharmacokinetics and toxicity in humans and laboratory animals following contrast agent administration	46
Origins, fate, and actions of methylated trivalent metabolites of inorganic arsenic: progress and prospects	46
Dapagliflozin suppresses ER stress and protects doxorubicin-induced cardiotoxicity in breast cancer patients	44
Functional alterations by a subgroup of neonicotinoid pesticides in human dopaminergic neurons	44
3D bioprinting of complex tissues in vitro: state-of-the-art and future perspectives	43
Ferroptosis as a mechanism of non-ferrous metal toxicity	43
Mechanisms of deoxynivalenol-induced endocytosis and degradation of tight junction proteins in jejunal IPEC-J2 cells involve selective activation of the MAPK pathways	41
Methanol-induced optic neuropathy: a still-present problem	40
Nrf2 deficiency aggravates the kidney injury induced by subacute cadmium exposure in mice	39
Neonicotinoids: mechanisms of systemic toxicity based on oxidative stress-mitochondrial damage	38
Metabolism-mediated cytotoxicity and genotoxicity of pyrrolizidine alkaloids	38
Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis	37
Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling	37