OOIR: Observatory of International Research

Papers

(The H4-Index of Archives of Toxicology is 41. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
NAD(P)+-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite	2155
Sex-specific differences in toxicology: does the sex make the poison?	1074
The effects of nanoplastics on toxicity of metals and metal nanoparticles: molecular mechanisms and health effects	696
SIRT3/GLUT4 signaling activation by metformin protect against cisplatin-induced ototoxicity in vitro	668
Optimized methods for measuring competitive binding of chemical substances to thyroid hormone distributor proteins transthyretin and thyroxine binding globulin	238
Single-cell RNA sequencing to reveal non-parenchymal cell heterogeneity and immune network of acetaminophen-induced liver injury in mice	211
miR-451a and miR-486-5p: biomarkers for benzene-induced hematotoxicity	152
Construction of testicular organoids and their applications in the field of toxicology	133
Induction of clastogenesis and gene mutations by carbamazepine (at its therapeutically effective serum levels) in mammalian cells and the dependence on human CYP2B6 enzyme activity	124
Neonatal opioid toxicity: opioid withdrawal (abstinence) syndrome with emphasis on pharmacogenomics and respiratory depression	117
7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells	113
Qualitative and quantitative in silico toxicity profiling of “angel dust”: phencyclidine (PCP) analogues as new psychoactive substances (3-HO-PCP, 3-MeO-PCP, 4-MeO-PCP, 3-HO-PCE, 3-MeO-PCE, 4-MeO-PCE)	100
Biodistribution and pulmonary toxicity of branched polyethyleneimine in rats following intratracheal and intravenous exposure	96
Green tea catechins: protectors or threats to DNA? A review of their antigenotoxic and genotoxic effects	93
Development of a QSAR model for predicting PPARα activation by PFAS based on human in vitro data of a comprehensive panel of legacy and novel PFAS	91
Schizantherin B alleviates cisplatin-induced ototoxicity and does not interfere cisplatin-based chemotherapy in a breast cancer model	89
The landscape of cocaine cytotoxicity and the role of sigma-1 receptor modulation and adulterant synergism	88
Unraveling the Hsp70-ROS-autophagy axis in pentachlorophenol-challenged lung and liver epithelial cells	87
In vitro evidence for estrogen receptor activity of selected phase II isoflavone metabolites	86
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity	86
Cell–cell contacts prevent t-BuOOH-triggered ferroptosis and cellular damage in vitro by regulation of intracellular calcium	83
Mutagenic and carcinogenic potency determinations for NDMA support the cumulative dose assumption underpinning the less-than-lifetime Threshold of Toxicological Concern	81
Comprehensive ubiquitome analysis reveals persistent mitochondrial remodeling disruptions from doxorubicin-induced cardiotoxicity in aged CD-1 male mice	81
THP-1-derived polarized macrophages differ by drug transporter transcriptomics, P-glycoprotein activity and rifampicin uptake kinetics	76
Influence of deoxynivalenol and zearalenone on the immunohistochemical expression of oestrogen receptors and liver enzyme genes in vivo in prepubertal gilts	67

Investigating the applicability domain of the hiPSC-based PluriLum assay: an embryotoxicity assessment of chemicals and drugs	62
Developmental brain lipidomics is influenced by postnatal chlorpyrifos exposure and APOE genetic background in mice	57
The role of redox signaling in mitochondria and endoplasmic reticulum regulation in kidney diseases	55
A modular strategy for the testing and assessment of non-genotoxic carcinogens	52
Exposure limits for indoor volatile substances concerning the general population: The role of population-based differences in sensory irritation of the eyes and airways for assessment factors	52
Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice	52
Oxidative stress-mediated DNA fragmentation involved in STING-dependent apoptosis in human keratinocytes by 5-amino-2-methylphenol under ambient UVB exposure	49
Whether aristolochic acid directly drives hepatocarcinogenesis: comprehensive investigations from mutational signatures to animal models	48
Whole cigarette smoke condensates of heated tobacco products disrupt cell adhesion and induce anoikis in human bronchial epithelial cells	48
In vitro-in silico analysis reveals that loss of tankyrase1/2 improves bile acid handling in genetically engineered HepG2 cultures	45
PFAS-like behavior of alkylimidazolium ionic liquids: chain-length–dependent toxicokinetics and PBTK-based risk implications	44
Chemical disruption of placental thyroid hormone signalling: a systematic review that highlights sex-specific effects	44
Identification, synthesis and quantification of eutylone consumption markers in a chemsex context	44
Evaluation of the toxicity of combustion smokes at the air–liquid interface: a comparison between two lung cell models and two exposure methods	44
Quantitative genotoxicity assessment of N-nitrosodimethylamine in mice by error-corrected next-generation sequencing and DNA methylation quantification for toxicity threshold determination	42
What do we currently know about Novichoks? The state of the art	42
Application of physiologically based (PBK) modeling to quantify the effect of the antibiotic tobramycin on bile acid levels in human plasma	41
In silico structural and mechanistic sights into the N-glycosidase mechanism of Shiga toxin	41