OOIR: Observatory of International Research

Papers

(The H4-Index of Archives of Toxicology is 40. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Recent aspects of the effects of zinc on human health	273
Inhibition and induction of CYP enzymes in humans: an update	161
Designer drugs: mechanism of action and adverse effects	133
Toxicology and pharmacology of synthetic organoselenium compounds: an update	125
Drug induced liver injury: an update	122
Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses	107
Organophosphorus compounds and oximes: a critical review	97
Mode of action-based risk assessment of genotoxic carcinogens	97
Interactions of polystyrene nanoplastics with in vitro models of the human intestinal barrier	95
Cancer drug resistance induced by EMT: novel therapeutic strategies	94
COVID-19 and drug-induced liver injury: a problem of plenty or a petty point?	89
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging	82
Arsenic intoxication: general aspects and chelating agents	74
Chemical carcinogen safety testing: OECD expert group international consensus on the development of an integrated approach for the testing and assessment of chemical non-genotoxic carcinogens	68
Environmental barium: potential exposure and health-hazards	68
Quantitative adverse outcome pathway (qAOP) models for toxicity prediction	65
A novel 3D intestine barrier model to study the immune response upon exposure to microplastics	62
A framework for establishing scientific confidence in new approach methodologies	61
An updated review on synthetic cathinones	60
Impairment of bile acid metabolism by perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in human HepaRG hepatoma cells	60
Cross-species analysis of hepatic cytochrome P450 and transport protein expression	56
Toxicology data of graphene-family nanomaterials: an update	55
Perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorononanoic acid (PFNA) increase triglyceride levels and decrease cholesterogenic gene expression in human HepaRG liver c	54
Cadmium induces renal inflammation by activating the NLRP3 inflammasome through ROS/MAPK/NF-κB pathway in vitro and in vivo	52
Current EU regulatory requirements for the assessment of chemicals and cosmetic products: challenges and opportunities for introducing new approach methodologies	52

Prediction reliability of QSAR models: an overview of various validation tools	49
The functions and regulation of heat shock proteins; key orchestrators of proteostasis and the heat shock response	49
An update on T-2 toxin and its modified forms: metabolism, immunotoxicity mechanism, and human exposure assessment	49
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) induce epigenetic alterations and promote human breast cell carcinogenesis in vitro	48
Prediction of oral hepatotoxic dose of natural products derived from traditional Chinese medicines based on SVM classifier and PBPK modeling	47
Human Family 1–4 cytochrome P450 enzymes involved in the metabolic activation of xenobiotic and physiological chemicals: an update	46
Comparing in vitro human liver models to in vivo human liver using RNA-Seq	46
Adverse outcome pathways for ionizing radiation and breast cancer involve direct and indirect DNA damage, oxidative stress, inflammation, genomic instability, and interaction with hormonal regulation	45
Neurofilament light chain: a specific serum biomarker of axonal damage severity in rat models of Chemotherapy-Induced Peripheral Neurotoxicity	44
Revisiting the evidence for genotoxicity of acrylamide (AA), key to risk assessment of dietary AA exposure	43
Hypoxia, oxidative stress, and immune evasion: a trinity of the trichothecenes T-2 toxin and deoxynivalenol (DON)	42
Toxicities of opioid analgesics: respiratory depression, histamine release, hemodynamic changes, hypersensitivity, serotonin toxicity	42
Origins, fate, and actions of methylated trivalent metabolites of inorganic arsenic: progress and prospects	41
Acute, reproductive, and developmental toxicity of essential oils assessed with alternative in vitro and in vivo systems	40
The evolution of strategies to minimise the risk of human drug-induced liver injury (DILI) in drug discovery and development	40