OOIR: Observatory of International Research

Papers

(The H4-Index of Archives of Toxicology is 38. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
A modular strategy for the testing and assessment of non-genotoxic carcinogens	894
Optimized methods for measuring competitive binding of chemical substances to thyroid hormone distributor proteins transthyretin and thyroxine binding globulin	270
Cell–cell contacts prevent t-BuOOH-triggered ferroptosis and cellular damage in vitro by regulation of intracellular calcium	246
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity	145
miR-451a and miR-486-5p: biomarkers for benzene-induced hematotoxicity	131
Induction of clastogenesis and gene mutations by carbamazepine (at its therapeutically effective serum levels) in mammalian cells and the dependence on human CYP2B6 enzyme activity	101
Influence of deoxynivalenol and zearalenone on the immunohistochemical expression of oestrogen receptors and liver enzyme genes in vivo in prepubertal gilts	93
SIRT3/GLUT4 signaling activation by metformin protect against cisplatin-induced ototoxicity in vitro	89
Novel insight into mechanisms for ATR activation by chromatin structures	84
Developmental brain lipidomics is influenced by postnatal chlorpyrifos exposure and APOE genetic background in mice	81
Single-cell RNA sequencing to reveal non-parenchymal cell heterogeneity and immune network of acetaminophen-induced liver injury in mice	73
7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells	72
Comprehensive ubiquitome analysis reveals persistent mitochondrial remodeling disruptions from doxorubicin-induced cardiotoxicity in aged CD-1 male mice	70
Estimating the reduction in US mortality if cigarettes were largely replaced by e-cigarettes	70
Sex-specific differences in toxicology: does the sex make the poison?	67
Unraveling the Hsp70-ROS-autophagy axis in pentachlorophenol-challenged lung and liver epithelial cells	63
Impaired intestinal stem cell activity in ETEC infection: enterotoxins, cyclic nucleotides, and Wnt signaling	62
Neonatal opioid toxicity: opioid withdrawal (abstinence) syndrome with emphasis on pharmacogenomics and respiratory depression	62
The role of redox signaling in mitochondria and endoplasmic reticulum regulation in kidney diseases	60
Mystery of methamphetamine-induced autophagosome accumulation in hippocampal neurons: loss of syntaxin 17 in defects of dynein–dynactin driving and autophagosome–late endosome/lysosome fusion	59
Investigating the applicability domain of the hiPSC-based PluriLum assay: an embryotoxicity assessment of chemicals and drugs	58
Activation of (un)regulated cell death as a new perspective for bispyridinium and imidazolium oximes	57
Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice	56
Exposure limits for indoor volatile substances concerning the general population: The role of population-based differences in sensory irritation of the eyes and airways for assessment factors	56
Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds—a hypo	55

The role of genetic polymorphisms for inducing genotoxicity in workers occupationally exposed to benzene: a systematic review	51
Canine coronavirus infection is intensified by 2,3,7,8-tetrachlorodibenzo-p-dioxin	51
Laser vs. thermal treatments of green pigment PG36: coincidence and toxicity of processes	47
Metabolism-mediated cytotoxicity and genotoxicity of pyrrolizidine alkaloids	46
Coenzyme Q0 defeats NLRP3-mediated inflammation, EMT/metastasis, and Warburg effects by inhibiting HIF-1α expression in human triple-negative breast cancer cells	45
Dynamically monitoring cellular γ-H2AX reveals the potential of carcinogenicity evaluation for genotoxic compounds	44
Yttrium chloride-induced cytotoxicity and DNA damage response via ROS generation and inhibition of Nrf2/PPARγ pathways in H9c2 cardiomyocytes	44
In vitro metabolism of helenalin and its inhibitory effect on human cytochrome P450 activity	42
N-acetyltransferase 2 acetylator genotype-dependent N-acetylation and toxicity of the arylamine carcinogen β-naphthylamine in cryopreserved human hepatocytes	41
ITGA1, the alpha 1 subunit of integrin receptor, is a novel marker of drug-resistant senescent melanoma cells in vitro	40
Effects of low concentrations of ozone gas exposure on percutaneous oxygen saturation and inflammatory responses in a mouse model of Dermatophagoides farinae-induced asthma	40
Perfluoroalkyl substances (PFASs) are substrates of the renal human organic anion transporter 4 (OAT4)	39
Application of physiologically based (PBK) modeling to quantify the effect of the antibiotic tobramycin on bile acid levels in human plasma	38
Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell models	38