OOIR: Observatory of International Research

Papers

(The H4-Index of Archives of Toxicology is 40. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Induction of clastogenesis and gene mutations by carbamazepine (at its therapeutically effective serum levels) in mammalian cells and the dependence on human CYP2B6 enzyme activity	1296
7-Hydroxycannabidiol and 7-carboxycannabidiol induced cytotoxicity via apoptosis and endoplasmic reticulum stress in human hepatic cells	483
Estimating the reduction in US mortality if cigarettes were largely replaced by e-cigarettes	356
Cell–cell contacts prevent t-BuOOH-triggered ferroptosis and cellular damage in vitro by regulation of intracellular calcium	155
SIRT3/GLUT4 signaling activation by metformin protect against cisplatin-induced ototoxicity in vitro	140
Investigating the applicability domain of the hiPSC-based PluriLum assay: an embryotoxicity assessment of chemicals and drugs	124
miR-451a and miR-486-5p: biomarkers for benzene-induced hematotoxicity	93
Influence of deoxynivalenol and zearalenone on the immunohistochemical expression of oestrogen receptors and liver enzyme genes in vivo in prepubertal gilts	91
Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity	86
Green tea catechins: protectors or threats to DNA? A review of their antigenotoxic and genotoxic effects	83
Unraveling the Hsp70-ROS-autophagy axis in pentachlorophenol-challenged lung and liver epithelial cells	80
Whether aristolochic acid directly drives hepatocarcinogenesis: comprehensive investigations from mutational signatures to animal models	79
Sex-specific differences in toxicology: does the sex make the poison?	79
Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds—a hypo	78
Exposure limits for indoor volatile substances concerning the general population: The role of population-based differences in sensory irritation of the eyes and airways for assessment factors	77
The role of redox signaling in mitochondria and endoplasmic reticulum regulation in kidney diseases	69
Comprehensive ubiquitome analysis reveals persistent mitochondrial remodeling disruptions from doxorubicin-induced cardiotoxicity in aged CD-1 male mice	68
NAD(P)+-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite	67
Biodistribution and intestinal inflammatory response following voluntary oral intake of silver nanoparticles by C57BL/6J mice	67
Neonatal opioid toxicity: opioid withdrawal (abstinence) syndrome with emphasis on pharmacogenomics and respiratory depression	65
Developmental brain lipidomics is influenced by postnatal chlorpyrifos exposure and APOE genetic background in mice	64
A modular strategy for the testing and assessment of non-genotoxic carcinogens	64
Construction of testicular organoids and their applications in the field of toxicology	63
Impaired intestinal stem cell activity in ETEC infection: enterotoxins, cyclic nucleotides, and Wnt signaling	61
Single-cell RNA sequencing to reveal non-parenchymal cell heterogeneity and immune network of acetaminophen-induced liver injury in mice	57

Dynamically monitoring cellular γ-H2AX reveals the potential of carcinogenicity evaluation for genotoxic compounds	56
Optimized methods for measuring competitive binding of chemical substances to thyroid hormone distributor proteins transthyretin and thyroxine binding globulin	56
In vitro metabolism of helenalin and its inhibitory effect on human cytochrome P450 activity	54
The role of genetic polymorphisms for inducing genotoxicity in workers occupationally exposed to benzene: a systematic review	52
What do we currently know about Novichoks? The state of the art	52
Perfluoroalkyl substances (PFASs) are substrates of the renal human organic anion transporter 4 (OAT4)	51
Effects of low concentrations of ozone gas exposure on percutaneous oxygen saturation and inflammatory responses in a mouse model of Dermatophagoides farinae-induced asthma	50
Molecular mechanisms behind ROS regulation in cancer: A balancing act between augmented tumorigenesis and cell apoptosis	49
Yttrium chloride-induced cytotoxicity and DNA damage response via ROS generation and inhibition of Nrf2/PPARγ pathways in H9c2 cardiomyocytes	48
Combined use of multiparametric high-content-screening and in vitro circadian reporter assays in neurotoxicity evaluation	47
In silico structural and mechanistic sights into the N-glycosidase mechanism of Shiga toxin	46
Development of a transcriptome-based determination of innate immune suppressor (TDIS) assay as an in vitro test for immunotoxicity	45
Internal exposure to heat-induced food contaminants in omnivores, vegans and strict raw food eaters: biomarkers of exposure to 2- and 3-monochloropropanediol (urinary excretion) and glycidol (hemoglob	44
Evaluation of the toxicity of combustion smokes at the air–liquid interface: a comparison between two lung cell models and two exposure methods	43
Impact of plastic-related compounds on the gene expression signature of HepG2 cells transfected with CYP3A4	42
In vitro-in silico analysis reveals that loss of tankyrase1/2 improves bile acid handling in genetically engineered HepG2 cultures	40
Canine coronavirus infection is intensified by 2,3,7,8-tetrachlorodibenzo-p-dioxin	40
Apelin-13 protects against cisplatin-induced ototoxicity by inhibiting apoptosis and regulating STAT1 and STAT3	40