Cephalalgia

Article	Citations
Evaluating the efficacy of CGRP mAbs and gepants for the preventive treatment of migraine: A systematic review and network meta-analysis of phase 3 randomised controlled trials	122
A missing piece in the puzzle of chronic dizziness: Dysautonomia	121
Evidence-based guidelines for the pharmacological treatment of migraine	92
Genetic characterization of the endocannabinoid system and psychiatric features in patients with migraine and medication overuse headache	87
Visual snow vs. migraine aura: Debate summary and novel insights into the syndrome	79
Persistent idiopathic facial pain: Integrating headache neurology insights into interdisciplinary guidelines	60
Efficacy of different cannabinoid compounds on migraine-like responses in female rats	51
International Classification of Headache Disorders-4 – Work in Progress 1	50
Introducing the four dimensions 4D migraine scale: A composite score proposal evaluating migraine severity and treatment efficacy	49
Corticosteroid-dependent increased expression of CGRP and its receptor subunits within the rodent trigeminal ganglion does not prompt cephalic allodynia	49
Chronic Migraine Epidemiology and Outcomes – International (CaMEO-I) Study: Methods and multi-country baseline findings for diagnosis rates and care	45
Harassment in the headache field: a global web-based cross-sectional survey	45
A reply, drug-induced reversible cerebral vasoconstriction syndrome: Lessons from the real world	44
Predictive value of preoperative white and gray matter microstructural alterations for microvascular decompression outcome in classical trigeminal neuralgia	43
Rethinking migraine with aura: Why cortical spreading depolarization (depression), not aura, causes headaches	42
Depression screening in migraine - A double-edged sword	41
IHC 2025 late-breaking abstracts	41
Childhood and adolescent headache: A problem not to be ignored in the era of new therapies	40
Impact of psychiatric comorbidity, resilience and executive function on childhood and adolescent headaches: A narrative review	40
Painful nervus intermedius neuropathy attributed to Bell's palsy: The need for independent diagnostic criteria	40
Population-based prevalence of cranial autonomic symptoms in migraine and proposed diagnostic appendix criteria	38
Effect of Altmetric score on manuscript citations: A randomized-controlled trial	38
The effects of certain TRP channels and voltage-gated KCNQ/Kv7 channel opener retigabine on calcitonin gene-related peptide release in the trigeminovascular system	37
Comment on “What predicts citation counts and translational impact in headache research? A machine learning analysis”	36
Triptan non-response in a London tertiary headache centre: What can we learn? A retrospective study	36

Guidelines of the International Headache Society for controlled trials of pharmacological preventive treatment for persistent post-traumatic headache attributed to mild traumatic brain injury	35
History of maternal migraine and its association with preeclampsia: A case–control study in a low-resource setting in Sudan, Africa	35
Genome-wide DNA methylation analysis in an antimigraine-treated preclinical model of cortical spreading depolarization	34
Corrigendum to: Evaluation of outcomes of calcitonin gene-related peptide (CGRP)-targeting therapies for acute and preventive migraine treatment based on patient sex	34
Paroxysmal hemicrania and hemicrania continua: Review on pathophysiology, clinical features and treatment	31
2025 Highlights in migraine prevention	31
An altered reward system characterizes chronic migraine with medication overuse headache	31
Systemic lupus erythematosus mimicking retinal migraine: a case report	31
A 7-year retrospective analysis of the management of children with acute headache presenting in a pediatric emergency department	30
Overlap between perceived triggers, premonitory symptoms and symptom persistence across migraine phases: A REFORM study	28
Sex differences in photophobic behaviors following cortical spreading depression in rats	26
Guidelines of the International Headache Society for Clinic-Based Headache Registries, 1 st edition	26
Genome sequencing reveals the Adgrl3 ( ADGRL3 ) gene as a possible cause of cephalic hypersensitivity in t	26
Galcanezumab modulates Capsaicin-induced C-fiber reactivity	25
COVID-19 vaccination-triggered cluster headache episodes with frequent attacks	25
The midfacial segment pain: little known disorder in need of scientific evaluation	24
Effect of COVID vaccination on monthly migraine days: a longitudinal cohort study	24
Author response to ‘Clarification on the incidence and sex-specificity of sexual dysfunction as an adverse event of CGRP-targeting medications’	24
Sensitivity of the SNNOOP10 list in the high-risk secondary headache detection	24
Safety profile of monoclonal antibodies targeting the calcitonin gene-related peptide system in pregnancy: Updated analysis in VigiBase®	23
Guidelines Update: Guidelines of the International Headache Society for controlled trials of preventive treatment of migraine in children and adolescents, 1st edition – An experience-based update	23
Crossing the Rubicon? The future impact of artificial intelligence on headache medicine	23
Comorbidity or combination – more evidence for cluster-migraine?	23
Long-term open-label and real-world studies of lasmiditan, ubrogepant, and rimegepant for the acute treatment of migraine attacks	22
Recognizing solitary pontine lesion–related trigeminal neuralgia as a distinct entity: The need for an updated ICHD classification	22
How do we facilitate individuals with recurrent headache and migraine receiving evidence-based behavioral treatment?	22
A placebo-controlled, randomized, single and multiple dose study to evaluate the safety, tolerability, and pharmacokinetics of rimegepant in healthy participants	22
Migraine attack incidence in relation to the post-ovulatory estrogen decline: A prospective cohort study	22
miR-382-5p and miR-34a in migraine: Expression in monocytes and a post-hoc exploratory comparison with expression in peripheral blood mononuclear cells	22
Looking at Cephalalgia from the inside	22
Genetic variability within molecular core clock genes in cluster headache	22
Greater occipital nerve block for the treatment of migraine: An umbrella review, systematic review, and meta-analysis	22
The non-decussating and decussating trigeminothalamic tracts in humans: A combination of connectome-based tractography and histological validation	21
Case reports: Could sexual dysfunction in women with migraine be a side effect of CGRP inhibition?	21
Physical impairment during and between migraine attacks: A daily diary study of patients with chronic migraine	21
Preclinical and clinical evaluation of LY3451838, a PACAP-neutralizing monoclonal antibody, in randomized, double-blind, placebo-controlled phase 1 and phase 2 studies involving healthy adults and adu	20
What is the evolutionary disadvantage of migraine?	20
Neck pain in migraine: A narrative review and steps to correct evaluation and treatment	20
Migraine and risk of atrial fibrillation: A 9-year follow-up based on the Trøndelag Health Study	20
Worldwide availability of medications for migraine and tension-type headache: A survey of the International Headache Society	19
The “index vein” as a sign for migraine aura in the emergency setting	19
Abnormal heart rate variability and its application in predicting treatment efficacy in patients with chronic migraine: An exploratory study	19
Alopecia as an emerging adverse event to CGRP monoclonal antibodies: Cases Series, evaluation of FAERS, and literature review	19
Thanks to Reviewers	19
Abstracts from the International Headache Congress 14–17 September 2023	19
Advancing understanding of migraine pathophysiology and therapy by consideration of patient sex	18
Muscae volitantes: A 19th-century precursor of visual snow syndrome?	18
Migraine-attributed burden, impact and disability, and migraine-impacted quality of life: Expert consensus on definitions from a Delphi process	18
Plasma adrenomedullin levels in migraine: A registry for migraine (REFORM) study	18
Effectiveness of anti-CGRP monoclonal antibodies and onabotulinumtoxinA in menstrually-related migraine: The unmet need of perimenstrual headache days	17

Are we closer to achieving precision medicine for migraine treatment? A narrative review	17
Letter to the Editor regarding “Effect of Altmetric score on manuscript citations: A randomized-controlled trial”	17
The effect of treatment onset time on acute efficacy in migraine patients treating with remote electrical neuromodulation (REN)	17
Are the ICHD-3 criteria for headache attributed to idiopathic intracranial hypertension valid? Headache phenotyping and field-testing in newly diagnosed idiopathic intracranial hypertension	17
Exploring the association between familial hemiplegic migraine genes ( CACNA1A , ATP1A2 and	17
Guidelines of the International Headache Society for Controlled Clinical Trials in Cluster Headache	17
Corneal confocal microscopy reveals nerve fiber alterations in migraine irrespective of subtype or visual hypersensitivity	16
Efficacy of eptinezumab in non-responders to subcutaneous monoclonal antibodies against CGRP and the CGRP receptor: A retrospective cohort study	16
Therapeutic dissociation of CGRP-targeted treatments in migraine and complex regional pain syndrome	16
Stroke due to small-vessel disease and migraine: A case–control study of a young adult with ischemic stroke population	16
Internet and social media's role in migraine education: Headache or not headache?	16
Premonitory symptoms in migraine: A REFORM Study	16
The impact of eating disorders on idiopathic intracranial hypertension	16
Corneal confocal microscopy identifies corneal nerve fiber loss in patients with migraine	16
2025 Highlights in digital technology in headache	15
Erratum	15
Comorbidity with fibromyalgia predicted poorer outcomes in patients with chronic migraine on flunarizine: Prospective proof-of-concept study	15
2025 highlights in non-invasive neurostimulation and neuromodulation for headache management	15
Brain imaging in migraine with and without aura: Similarities and differences	15
Shared genetics and causal relationships between migraine and thyroid function traits	15
Neurological and psychiatric comorbidities of migraine: Concepts and future perspectives	15
HEAD-WINd ® : A nationwide cohort study of headache disorders in danish adults using survey, smartphone and registry data	15
Two-year, real-world erenumab persistence and quality of life data in 82 pooled patients with abrupt onset, unremitting, treatment refractory headache and a migraine phenotype: New daily persistent he	15
Efficacy and safety of monoclonal antibodies targeting CGRP in migraine prevention. GRADE tables elaborated by the ad hoc working group of the International Headache Society	15
Pan-American migraine prevalence: Findings from the Americas’ migraine observatory study (AMIGOS)	15
Efficacy and safety of eptinezumab in a predominantly Asian population with chronic migraine: Results of the randomized, double-blind, placebo-controlled SUNRISE trial	14
The long-term effect of work schedule, shift work disorder, insomnia and restless legs syndrome on headache among nurses: A prospective longitudinal cohort study	14
The clinical outcome of patients starting monoclonal antibodies anti-CGRP with concomitant migraine preventive treatments	14
Electrophysiological findings in migraine may reflect abnormal synaptic plasticity mechanisms: A narrative review	14
Reply to “Methodological considerations in assessing the impact of CGRP monoclonal antibodies on blood pressure”	14
Comment on “Lack of reproducibility of resting-state functional MRI findings in migraine with aura”	14
Recurrent Painful Ophthalmoplegic Neuropathy: A case report with atypical features and a review of the literature	13
Hypnic Headache – What do we know in 2022?	13
Comparison of continuous headache features in youth with migraine, new daily persistent headache, and persistent post-traumatic headache	13
Headache at the chronic stage of cerebral venous thrombosis	13
It's not either-or: Why migraine care needs both real-world evidence studies and randomized controlled trials	13
Switching anti-CGRP(R) monoclonal antibodies in multi-assessed non-responder patients and implications for ineffectiveness criteria: A retrospective cohort study	13
Cigarette smoking history (personal and secondary childhood exposure) in non-cluster headache trigeminal autonomic cephalalgias: A clinic based study	13
“Wearing-off” efficacy of CGRP monoclonal antibodies for migraine prevention: A meta-analysis of randomized controlled trials	13
New migraine drugs: A critical appraisal of the reason why the majority of migraine patients do not receive an adequate medication	13
Corrigendum: No structural brain alterations in new daily persistent headache – a cross sectional VBM/SBM study	13
Children under 6 years with acute headache in Pediatric Emergency Departments. A 2-year retrospective exploratory multicenter Italian study	13
Prevalence and treatment of typical and atypical headaches in patients with Chiari I malformation: A meta-analysis and literature review	13
Proposed general diagnostic criteria for secondary headaches	13
Longitudinal trajectories of posttraumatic headache after pediatric mild traumatic brain injury	13
Avoidance behaviour modulates but does not condition phonophobia in migraine	13
Research to improve headache classification: Results, methods, and future challenges	13
2025 highlights in headache in children and adolescents	12
Adjunctive occipital nerve block for emergency treatment of acute migraine: A randomized, controlled trial	12
Late Breaking Author Index	12
Cephalalgia : a legacy of excellence, a vision for tomorrow	12
Orofacial pain for clinicians: A review of constant and attack-like facial pain syndromes	12
Opening of ATP-sensitive potassium channels activates meningeal nociceptors: Implications for the origin of migraine headache	12
Multidisciplinary headache treatment with work-focus in Norway: An observational study	12
Hypersensitivity to CGRP as a predictive biomarker of migraine prevention with erenumab	12
Longitudinal differences in iron deposition in periaqueductal gray matter and anterior cingulate cortex are associated with response to erenumab in migraine	12
Classification of solitary pontine lesion–related trigeminal neuralgia	12
Generative chatbots in headache education and research: A narrative review	12
Timing of headache after COVID-19 vaccines and its association with cerebrovascular events: An analysis of 41,700 VAERS reports	12
Comment on ‘'Correlation between endometriosis and migraine features: Results from a prospective case-control study'‘	12
Open-label trials for CGRP-targeted drugs in migraine prevention: A narrative review	12
Other primary headaches: Distinct clinical features and uncertain pathophysiology	12
Molecular triggers of migraine aura: A systematic review of human pharmacological provocation studies	12
2025 Highlights in acute migraine treatment	12
Addressing unmet needs in migraine: Real-world fremanezumab effectiveness in participants of the PEARL study with at least three prior preventive treatment failures	12
Developing an artificial intelligence-based headache diagnostic model and its utility for non-specialists’ diagnostic accuracy	11
Oxygen inhalation has no effect on provoked cranial autonomic symptoms using kinetic oscillation stimulation in healthy volunteers	11
Migraine and the risk of stroke in a middle-aged and elderly population: A prospective cohort study	11
Recovery and long-term outcome after neurosurgical closure of spinal CSF leaks in patients with spontaneous intracranial hypotension	11
An evolving machine-learning-based algorithm to early predict response to anti-CGRP monoclonal antibodies in patients with migraine	11
Epicranial headaches part 2: Nummular headache and epicrania fugax	11
Persistent headache attributed to past cervicocephalic artery dissection: clinical characteristics and contributors to headache persistence	11
Transition of headache care from childhood to adulthood: Focusing needs, barriers, and models of care. A position paper of the IHS Child and Adolescent Committee	11
How migraine and its associated treatment impact on pregnancy outcomes: Umbrella review with updated systematic review and meta-analysis	11
Health care resource utilization and costs associated with diagnosed medication overuse headache and potential acute medication overuse in individuals with migraine	10
Treatment experiences and clinical characteristics in migraine and tension-type headache patients before the first visit to a tertiary headache center	10
Levels of migraine controls following International Headache Society (IHS) recommendations with eptinezumab: Effectiveness and tolerability in a 24-week, prospective multicenter study (the TACHIS stud	10
Where are the men? A systematic review of sex bias in human provocation models of migraine	10
Open label experience of repeated OnabotulinumtoxinA injections towards the sphenopalatine ganglion in patients with chronic cluster headache and chronic migraine	10
Overuse of analgesics can affect the fertility biomarker Anti-Müllerian Hormone in females. A translational study	10

Phenotyping non-idiopathic pseudotumor cerebri syndrome – A prospective cohort study	10
The psychometric properties of an e-headache diary in migraine	10
Personal view: Modelling pain mechanisms of migraine without aura	10
Update in the understanding of new daily persistent headache	10
Pathophysiology of cluster headache: From the trigeminovascular system to the cerebral networks	10
Migraine and risk of hypertensive disorders of pregnancy: A population-based cohort study	10
Lack of a direct link between macular cones function and photophobia in interictal migraine	10
Severity of physical, emotional, and cognitive symptoms is associated with future persistence of acute post-traumatic headache attributed to mild traumatic brain injury	10
Migraine as a primary care-sensitive condition: Building pathways to accessible care	10
The SIH-EBP Score: A grading scale to predict the response to the first epidural blood patch in spontaneous intracranial hypotension	10
Reaching international consensus on the definition of refractory migraine using the Delphi method	9
Functional magnetic resonance imaging in migraine: A systematic review	9
It is a long way to the top if you wanna citations?	9
Investigations of the migraine-provoking effect of levcromakalim in patients with migraine with aura	9
The evolutionary meaning of migraine	9
Substance P and the trigeminovascular system: From preclinical mechanisms to human headache induction	9
2025 highlights in resistant and refractory migraine	9
ANODYNE study: A double-blind randomized trial of greater occipital nerve block of methylprednisolone and lignocaine versus placebo as a transitional preventive treatment for episodic cluster headache	9
Migraine and insufficient sleep: The effect of sleep restriction on nociceptive evoked potentials in migraine	9
Therapeutic dissociation of CGRP-targeted treatments in migraine and complex regional pain syndrome: Authors’ reply	9
Transition of cluster headache phenotype: An interview-based study	9
Update on cough, exertional and sex headache	9
Bioequivalence of rimegepant, a small molecule CGRP receptor antagonist, administered as an oral tablet, a sublingual orally disintegrating tablet, and a supralingual orally disintegrating tablet: two	9
The monoclonal CGRP-receptor blocking antibody erenumab has different effects on brainstem and cortical sensory-evoked responses	8
Diagnosis of idiopathic intracranial hypertension: A proposal for evidence-based diagnostic criteria	8
What's a migraine day? Analysis of the variety in the definition of a migraine day across phase III trials with drugs targeting the CGRP pathway	8
Sensitizing effect of antimigraine drug sumatriptan on capsaicin-sensitive lung vagal neurons via 5-HT 1B/1D receptors and PKA: Relevance to adverse	8
Pharmacologic characterization of atogepant: A potent and selective calcitonin gene–related peptide receptor antagonist	8
A narrative review of app- and internet-delivered headache interventions: From ideation to implementation and the future	8
Cannabinoids rescue migraine symptoms caused by central CGRP administration in mice	8
Effectiveness of anti-CGRP monoclonal antibodies on central symptoms of migraine	8
Cranial autonomic symptoms as a protective mechanism in patients with chronic migraine: A cross-sectional study	8
Visually-induced hemodynamic response and white matter hyperintensities in middle-aged women with ischemic stroke or migraine with aura	8
Identification of patients with chronic migraine by using sensory-evoked oscillations from the electroencephalogram classifier	8
Identification of brain areas in mice with peak neural activity across the acute and persistent phases of post-traumatic headache	8
Reviewing the complex relationship between circadian rhythms and cluster headache	8
Investigations of the subarachnoid space as a potential link between aura and headache in migraine: A case-control MRI study	8
Safety, tolerability, and efficacy of atogepant added to onabotulinumtoxinA for the preventive treatment of chronic migraine: A phase 3, multicenter, 24-week, open-label study	8
Studying migraine as a risk factor for stroke: The importance of working with an explicit causal framework	8
Comment on: Setting higher standards for migraine prevention: A position statement of the International Headache Society	8
Corrigendum to: “ CLOCK gene circannual expression in cluster headache”	8
Prolonged headache with vaccine- and dose-specific headache pattern associated with vaccine against SARS-CoV-2 in patients with migraine	8
A randomized open-label study to evaluate the effectiveness and safety of once-daily rimegepant 75 mg orally disintegrating tablet for the short-term preventive treatment of fasting-triggered headache	8
Evoked potential studies in migraine: A systematic review of neurophysiological patterns across migraine subtypes	8
Visual snow syndrome is probably not mediated by CGRP: A case series	8
Thanks to Reviewers	7
Medication “underuse” headache	7
Enhanced audiovisual associative pair learning in migraine without aura in adult patients: An unexpected finding	7
Epidemiology and clinical features of short-lasting unilateral neuralgiform headache attacks: A systematic review and meta-analysis	7
Prevalence, clinical characteristics and associated factors of cardiac cephalalgia: A prospective study	7
Biodistribution of atogepant and rimegepant in mouse peripheral and central structures of relevance to migraine pathogenesis	7
Longitudinal analysis of pain-induced brain activations in post-traumatic headache	7
Functional brainstem representations of the human trigeminal cervical complex	7
What proportion of people with migraine report postdromal symptoms? A systematic review and meta-analysis of observational studies	7
Complementary, but not equivalent: Clarifying the role of RWE and RCT in migraine research	7
Physical activity in migraine: Identifying an engagement threshold and patient clusters in a population-based cohort	7
Effectiveness and tolerability of pharmacological prophylaxis in migraine patients with prior preventive treatment failure: A systematic review and network meta-analysis of randomized controlled trial	7
Preventive CGRP-targeted therapies for chronic migraine with and without medication-overuse headache	7
Building community and visibility: A year of social media growth for Cephalalgia	7
Diagnosis, knowledge, perception, and productivity impact of headache education and clinical evaluation program in the workplace at an information technology company of more than 70,000 employees	7
Pharmacological modulation of ventral tegmental area neurons elicits changes in trigeminovascular sensory processing and is accompanied by glycemic changes: Implications for migraine	7
Nerve matters: Longitudinal microstructural change in the trigeminal nerve is associated with durable pain relief after surgery for trigeminal neuralgia	7
Continuous positive airway pressure in cluster headache: A randomized, placebo-controlled, triple-blind, crossover study	7
Raising the bar in migraine prevention: Toward freedom and optimal control	7
Minimal important difference of the Migraine Disability Assessment (MIDAS): Longitudinal data from the DMKG Headache Registry	7
Methodology of drug trials in migraine: History and suggestions for the future	7
Migraine stigma and general knowledge of migraine: A cross-sectional European survey	7
A male-specific mechanism of meningeal nociceptor sensitization promoting migraine headache	7
Neuromodulation in trigeminal autonomic cephalalgias: 11-year experience of non-invasive vagus nerve stimulation	7
A comparative study on prophylactic efficacy of cinnarizine and amitriptyline in childhood migraine: a randomized double-blind clinical trial	7
Indirect crosstalk between signalling pathways activated by CGRP and Piezo1 in human iPSC-derived endothelial cells relevant to migraine	6
Author Index	6
Transcultural headache medicine: A framework for integrating cultural contexts into headache science and care – a call to action from the International Headache Society	6
The effect of blood pressure lowering medications on the prevention of episodic migraine: A systematic review and meta-analysis	6
Sex differences in effectiveness of CGRP receptor antagonism for treatment of acute and persistent headache-like pain in a mouse model of mild traumatic brain injury	6
Pediatric screen exposure and school related headache disability	6
Headache prevalence and types in multiple sclerosis and related neuroimmunological diseases: A multicenter study	6
Promoting excellence in scientific peer review: The Cephalalgia Reviewer Academy	6
Placebo and nocebo in the treatment of migraine: How much does real world effectiveness depend on contextual effects?	6
A response: Update on cough, exertional and sex headache	6
An analysis of diffusion tensor imaging in classical trigeminal neuralgia	6
Impact and care gaps of headache disorders in active-duty military personnel: A cross-sectional study from a European armed forces population	6
The role of cytokines in migraine: A systematic review	6
New migraine drugs	6
Inhibiting PAC1 receptor internalization and endosomal ERK pathway activation may ameliorate hyperalgesia in a chronic migraine rat model	6
Effects of substance P on headache induction and arterial dilation in healthy adults	6
CLOCK gene circannual expression in cluster headache	6
Differences in cortical morphometry between persistent post-traumatic headache, migraine and healthy controls	6
Identification and characterization of migraine in pregnancy: A Norwegian registry-based cohort study	6
Effectiveness of onabotulinumtoxinA (BOTOX®) for the preventive treatment of chronic migraine: A meta-analysis on 10 years of real-world data	6
Effectiveness of transcranial direct current stimulation and monoclonal antibodies acting on the CGRP as a combined treatment for migraine (TACTIC): Results of a randomized controlled trial	6
Long-term outcomes of nummular headache: A series of 168 patients and 1198 patient-years of follow-up	5
Insufficient sleep may alter cortical excitability near the migraine attack: A blinded TMS crossover study	5
Increased prevalence of migraine in women with inflammatory bowel disease: A cross-sectional study	5
Patterns of migraine medication use in Norway: A nationwide registry-based observational study	5