OOIR: Observatory of International Research

Papers

(The TQCC of Clinical and Experimental Pharmacology and Physiology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
	55
Issue Information	49
Efficacy and safety of baricitinib for the treatment of moderate‐to‐severe atopic dermatitis: A systematic review and meta‐analysis of randomized clinical trials	43
Ablation of TRPC3 compromises bicarbonate and phosphate transporter activity in mice proximal tubular cells	41
Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3‐mediated ZO‐1 expression	35
Reliability of Matrix‐Assisted Laser Desorption‐Ionisation Time‐of‐Flight Mass Spectrometry as a Method for Drug‐Resistant Tuberculosis Gene Identification	33
Glycyrrhizic Acid Ameliorates LPS‐Induced WI‐38 Cell Inflammation, Oxidative Stress, and Ferroptosis via Targeting METTL14 in Infantile Pneumonia	28
Fibroblast growth factor 10 ameliorates renal ischaemia–reperfusion injury by attenuating mitochondrial damage	25
LncRNA PRKCQ‐AS1 regulates paclitaxel resistance in triple‐negative breast cancer cells through miR‐361‐5p/PIK3C3 mediated autophagy	24
Ulinastatin affects focal cerebral ischemia–reperfusion injury via SOCS1‐mediated JAK2/STAT3 signalling pathway	22
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Weight‐based oxytocin infusion for preventing uterine atony during caesarean delivery in non‐labouring patients: A dose–response study	20
Development and Validation of a Comprehensive Risk Prediction Model for Polypoid Lesions of the Gallbladder	19
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Corticosterone‐Induced Myocardial Dysfunctions and the Cardioprotective Role of Tauroursodeoxycholic Acid: An Experimental Study in Mice	17
ALKBH5 inhibits the SIRT3/ACC1 axis to regulate fatty acid metabolism via an m6A‐IGF2BP1‐dependent manner in cervical squamous cell carcinoma	17
Effects of a single dose of rocuronium in patients with different body fat percentages: A randomised controlled trial	16
SIRT1 targeted by miR‐211‐5p regulated proliferation and apoptosis of Dex‐treated growth plate chondrocytes via mediating SOX2	16
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Correction to “low‐intensity pulsed ultrasound prevents prolonged hypoxia‐induced cardiac fibrosis through HIF ‐1α/ DNMT3a	14
Ginsenoside Rh4 inhibits the malignant progression of multiple myeloma and induces ferroptosis by regulating SIRT2	14
Sympathetic Nerve Activation Drives Cardiac Fibrosis and Arrhythmia in Lean Metabolic Dysfunction‐Associated Steatohepatitis Mice Concurrently Exposed to Ethanol and a High‐Fat/High‐Cholesterol Diet	14
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Indole‐3‐Propionic Acid Improves Vascular Function in High‐Fat Diet‐Induced Obese Mice via eNOS	14

Issue Information	13
Issue Information	13
Pyroptosis‐Mediated Antitumor Activity of Cinobufagin in Non‐Small Cell Lung Cancer	13
Adrenalectomy attenuates hyperalgesia but does not regulate muscle wasting in a female rat model of fibromyalgia	12
BRAP Homologue Deficiency Exacerbates Airway Inflammation in Mouse Models of Experimental Asthma‐Like Disease	12
EZH2 promotes the progression of osteosarcoma through the activation of the AKT/GSK3β pathway	12
AEBP1 restores osteoblastic differentiation under dexamethasone treatment by activating PI3K/AKT signalling	11
Bufalin reduces myocardial infarction‐induced myocardial fibrosis and improves cardiac function by inhibiting the NLRP3/IL‐1β signalling pathway	11
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Protective effect of melatonin and ascorbic acid combination on sepsis‐induced lung injury: An Experimental study	11
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Artesunate alleviates psoriasis‐like dermatitis by reducing interleukin‐23 expression in tumor necrosis factor‐alpha‐induced HaCaT cells	10
Sex Steroid Control of Serotonergic System: Clinical Implications for Psychiatric Disorders and Addiction Treatment	10
GSK3β inhibitor TDZD8 ameliorates brain damage through both ROS scavenging and inhibition of apoptosis in hyperglycaemic subarachnoid haemorrhage rats	10
Erythropoietin hyporesponsiveness in non‐alcoholic fatty liver disease	10
Thioredoxin‐1 regulates the autophagy induced by oxidative stress through LC3‐II in human lens epithelial cells	10
TLR4 Inhibitor TAK‐242 Protected Henoch–Schonlein Purpura Nephritis in Rats by Regulating Inflammatory Response and Immune Competence via NF‐ κB/NLRP3<	10
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BCR::ABL1‐positive chronic myeloid leukaemia with CALR mutation	9
RETRACTION : Diosmetin Exerts Cardioprotective Effect on Myocardial Ischaemia Injury in Neonatal Rats by Decreasing Oxidative Stress and Myocardial Apoptosis	9
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Therapeutic potential of curcumin in ARDS and COVID‐19	9
A spontaneous hyperglycaemic cynomolgus monkey presents cognitive deficits, neurological dysfunction and cataract	9
Sevoflurane‐induced P300 promotes neuron apoptosis via Sp1/CDK9 pathway	9
Phosphatidylserine accelerates wound healing and reduces necrosis in the rats: Growth factor activation	9
Rapid detection of guttae area using aniline blue staining in Fuchs endothelial corneal dystrophy mouse model	9
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Prognostic value of inflammatory and nutritional indexes among advanced NSCLC patients receiving PD‐1 inhibitor therapy	8
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Sirt6, Deubiquitinated and Stabilised by USP9X, Takes Essential Actions on the Pathogenesis of Experimental Autoimmune Myasthenia Gravis by Regulating CD4⁺ T Cells	8
Metabolomic modelling and neuroprotective effects of carvacrol against acrylamide toxicity in rat's brain and sciatic nerve	8
Electroacupuncture Attenuates Cerebral Ischemia–Reperfusion Injury by Inhibiting Ferroptosis via the p53/SLC7A11 Pathway	8
Isoferulic Acid Inhibits Proliferation and Migration of Pancreatic Cancer Cells, and Promotes the Apoptosis of Pancreatic Cancer Cells in a Mitochondria‐Dependent Manner Through Inhibiting NF	8
In vitro effects and mathematical modelling of CTCE‐9908 (a chemokine receptor 4 antagonist) on melanoma cell survival	8
Hsa_circ_0001204 modulates inflammatory response of macrophages infected by Mycobacterium tuberculosis via TLR4/NF‐κB signalling pathway	8
Esculentoside A ameliorates DNCB‐induced atopic dermatitis by suppressing the ROS‐NLRP3 axis via activating the Nrf2 pathway	8
Nicorandil mitigates amiodarone‐induced pulmonary toxicity and fibrosis in association with the inhibition of lung TGF‐β1/PI3K/Akt1‐p/mTOR axis in rats	8
Issue Information	8
Agomelatine alleviates steroid‐induced osteoporosis by targeting SIRT1/RANKL/FOXO1/OPG signalling in rats	8
Kruppel‐Like Factor 5 Modulates the Nuclear Factor Erythroid‐2‐Related Factor 2/Heme Oxygenase 1 Signalling Pathway to Regulate Vascular Smooth Muscle Cell Ferroptosis in Abdominal Aortic Aneurysm	7
Issue Information	7
A 2‐week treatment with 5‐azacytidine improved the hypercontractility state in prostate from obese mice: Role of the nitric oxide‐cyclic guanosine monophosphate signalling pathway	7
Global, Regional, and National Temporal Trend and Patterns of Change in the Burden of Asthma From 1990 to 2021: An Analysis of the Global Burden of Disease Study 2021	7
Relationship between serum CHIP levels with cardiovascular disease in maintenance haemodialysis patients	7
Issue Information	7
Kaempferol Ameliorates Sepsis‐Acute Lung Injury by Promoting Succinylation of SRPK1	7
Hsa_circ_0097922 promotes tamoxifen resistance and cell malignant behaviour of breast cancer cells by regulating ACTN4 expression via miR‐876‐3p	7
Endothelin System Blockade Extenuates Sepsis‐Induced Acute Heart and Kidney Injuries via Modulating ET‐1/Klotho/p38‐MAPK	6
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Ajugoside Promotes the Repair of Osteoporotic Bone by Inducing Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells	6

Issue Information	6
Scutellarin inhibits oleic acid induced vascular smooth muscle foam cell formation via activating autophagy and inhibiting NLRP3 inflammasome activation	6
COX17 Attenuates Diabetes‐Associated Retinal Injury by Improving Mitochondrial Function	6
Comprehensive analysis of EphA2 in pan‐cancer: A prognostic biomarker associated with cancer immunity	6
Exosomal miR‐21‐5p derived from multiple myeloma cells promote renal epithelial–mesenchymal transition through targeting TGF‐β/SMAD7 signalling pathway	6
The TNF ‐α– FABP4 –Dhhc7 Axis Mediates Olanzapine‐Induced Insulin Resistance in Rats and Humans	6
Synergic actions of botulinum neurotoxin A and oxaliplatin on colorectal tumour cell death through the upregulation of TRPM2 channel‐mediated oxidative stress	6
Aurora A‐Mediated Exosomal Secretion of miR ‐644a Promotes T‐Lymphocyte Apoptosis Through the NOXA	6
Overexpression of miR‐718 in Keratinocytes Affects the Psoriatic Inflammation via Targeting STAT1: In Vitro and In Vivo Evidence	6
Whole‐exome sequencing‐based mutational profiling of hepatocellular adenoma malignant transformation to hepatocellular carcinoma	6
GLP‐1 receptor agonist liraglutide alleviates kidney injury by regulating nuclear translocation of NRF2 in diabetic nephropathy	6
Propofol attenuates prostate cancer progression by upregulating TRHDE‐AS1 expression, and METTL14 could mediate its m6A modification	6
Disk diffusion‐based method aids in the detection of vanM‐positive Enterococcus faecium with low vancomycin minimum inhibitory concentrations	5
Issue Information	5
Study on the anti‐inflammatory effect of stachyose by inhibiting TLR4/NF‐κB signalling pathway in vitro and in vivo	5
Effectiveness and Safety of Omalizumab in the Adjuvant Treatment of Patients With Refractory Acute Urticaria: A Real‐World Case–Control Study	5
Association between dietary inflammation index and inflammatory bowel disease in adults: Results from National Health and Nutrition Examination Survey 2009–2010	5
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Relationship Between Long‐Term Exposure to Airborne Particulate Matter and the Intrinsic Capacity of Middle‐Aged and Older Adults in China: A Retrospective Cohort Study Based on	5
Shikonin ameliorates oxidative stress and neuroinflammation via the Akt/ERK/JNK/NF‐κB signalling pathways in a model of Parkinson's disease	5
Growth hormone‐releasing hormone beyond cancer	5
Restoring Autophagy by Exercise Ameliorates Insulin Resistance Partly via Calcineurin‐Driven TFEB Nuclear Translocation	5
Interaction of mtROS ‐Immune‐Inflammatory Vicious Cycle Activation in Sepsis‐Induced Cardiomyopathy	5
PD‐L1/PD‐L1 signalling promotes colorectal cancer cell migration ability through RAS/MEK/ERK	5
Impact of JAK/STAT inhibitors on human monocyte‐derived‐macrophages stimulated by cigarette smoke extract and lipopolysaccharide	5
Caffeic acid phenethyl ester ameliorates colistin‐induced nephrotoxicity in rats via modulation of FOXO1 /Nrf2/Sirt1 axis	5
Linarin Relieves Apoptosis, Inflammation and Oxidative Stress in LPS‐Induced Acute Kidney Injury by Modulating COX2	5
Tabersonine Alleviates Cerebral Ischemia/Reperfusion Injury Partly via Repressing the SLC6A2 / NF	5
Loganin exerts neuroprotective effect by inhibiting neuronal pyroptosis in rat with cerebral haemorrhage	5
Electroacupuncture Alleviates Focal Cerebral Ischemia–Reperfusion Injury and Is Associated With Modulation of Autophagy‐Ferroptosis Involving the STAT3	5