OOIR: Observatory of International Research

Papers

(The TQCC of Neuropathology and Applied Neurobiology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Invited Review: The spectrum of neuropathology in COVID‐19	91
Intracerebral endotheliitis and microbleeds are neuropathological features of COVID‐19	87
Brain tumour diagnostics using a DNA methylation‐based classifier as a diagnostic support tool	57
Dysfunction of the blood–brain barrier in Alzheimer's disease: Evidence from human studies	52
Neuropathological findings in two patients with fatal COVID‐19	51
Peripheral inflammation exacerbates α‐synuclein toxicity and neuropathology in Parkinson's models	49
Systematic review of human post‐mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease	38
Classification of diseases with accumulation of Tau protein	36
Cell senescence in neuropathology: A focus on neurodegeneration and tumours	33
Deep learning‐based model for diagnosing Alzheimer's disease and tauopathies	32
NLRP3 inflammasome and endoplasmic reticulum stress in the epileptogenic zone in temporal lobe epilepsy: molecular insights into their interdependence	32
Loss of the metabolism and sleep regulating neuronal populations expressing orexin and oxytocin in the hypothalamus in amyotrophic lateral sclerosis	31
A case series of Diffuse Glioneuronal Tumours with Oligodendroglioma‐like features and Nuclear Clusters (DGONC)	27
Identification of intraneuronal amyloid beta oligomers in locus coeruleus neurons of Alzheimer’s patients and their potential impact on inhibitory neurotransmitter receptors and neuronal excitability	24
Distinct brain‐derived TDP‐43 strains from FTLD‐TDP subtypes induce diverse morphological TDP‐43 aggregates and spreading patterns in vitro and in vivo	24
White matter alterations in Alzheimer’s disease without concomitant pathologies	22
A systems‐level analysis highlights microglial activation as a modifying factor in common epilepsies	21
Impaired brain insulin signalling in Parkinson's disease	21
Utrophin modulator drugs as potential therapies for Duchenne and Becker muscular dystrophies	21
CTNNB1 mutations are clonal in adamantinomatous craniopharyngioma	21
STochastic Optical Reconstruction Microscopy (STORM) reveals the nanoscale organization of pathological aggregates in human brain	21
Machine learning‐based decision tree classifier for the diagnosis of progressive supranuclear palsy and corticobasal degeneration	21
MRI and pathology correlations in the medulla in sudden unexpected death in epilepsy (SUDEP): a postmortem study	20
Invited Review – Understanding cause and effect in Alzheimer's pathophysiology: Implications for clinical trials	19
Review: Microglia in motor neuron disease	19

Heterozygous CAPN3 missense variants causing autosomal‐dominant calpainopathy in seven unrelated families	19
A polyphenotypic malignant paediatric brain tumour presenting a MN1‐PATZ1 fusion, no epigenetic similarities with CNS High‐Grade Neuroepithelial Tumour with MN1 Alteration (CNS HGNET‐MN1	19
Hippocampal subfield pathologic burden in Lewy body diseases vs. Alzheimer’s disease	19
N‐terminal heterogeneity of parenchymal and vascular amyloid‐β deposits in Alzheimer’s disease	19
Novel CAPN3 variant associated with an autosomal dominant calpainopathy	18
Novel clinicopathological characteristics differentiate dementia with Lewy bodies from Parkinson’s disease dementia	18
Correlations in post‐mortem imaging‐histopathology studies of sporadic human cerebral small vessel disease: A systematic review	18
Plectin dysfunction in neurons leads to tau accumulation on microtubules affecting neuritogenesis, organelle trafficking, pain sensitivity and memory	17
Differential brain region‐specific expression of MeCP2 and BDNF in Rett Syndrome patients: a distinct grey‐white matter variation	17
TDP43 proteinopathy is associated with aberrant DNA methylation in human amyotrophic lateral sclerosis	17
Neutrophil extracellular traps (NETs) infiltrate haematoma and surrounding brain tissue after intracerebral haemorrhage: A post‐mortem study	16
Molecular pathophysiology of human MICU1 deficiency	16
Olfactory bulb SARS‐CoV‐2 infection is not paralleled by the presence of virus in other central nervous system areas	16
The autophagy‐enhancing drug carbamazepine improves neuropathology and motor impairment in mouse models of Machado–Joseph disease	15
The S1PR2‐CCL2‐BDNF‐TrkB pathway mediates neuroinflammation and motor incoordination in hyperammonaemia	15
Neurodegenerative movement disorders: An epigenetics perspective and promise for the future	15
NOTCH3 variant position is associated with NOTCH3 aggregation load in CADASIL vasculature	15
Spinal manifestations of CLN1 disease start during the early postnatal period	15
Vimentin citrullination probed by a novel monoclonal antibody serves as a specific indicator for reactive astrocytes in neurodegeneration	15
Signs of early cellular dysfunction in multiple system atrophy	15
Non‐coding regulatory elements: Potential roles in disease and the case of epilepsy	14
Intranuclear inclusions in skin biopsies are not limited to neuronal intranuclear inclusion disease but can also be seen in oculopharyngodistal myopathy	14
A rare case of paediatric astroblastoma with concomitant MN1‐GTSE1 and EWSR1‐PATZ1 gene fusions altering management	14
Balloon cells promote immune system activation in focal cortical dysplasia type 2b	14
Robust methylation‐based classification of brain tumours using nanopore sequencing	14
Necrosome‐positive granulovacuolar degeneration is associated with TDP‐43 pathological lesions in the hippocampus of ALS/FTLD cases	14
Significance of cytosolic cathepsin D in Alzheimer's disease pathology: Protective cellular effects of PLGA nanoparticles against β‐amyloid‐toxicity	13
TRAPPC11‐related muscular dystrophy with hypoglycosylation of alpha‐dystroglycan in skeletal muscle and brain	13
Impaired myelin production due to an intrinsic failure of oligodendrocytes in mTORpathies	13
Expression pattern of perilipins in human brain during aging and in Alzheimer's disease	13
Lipid alterations in human frontal cortex in ALS‐FTLD‐TDP43 proteinopathy spectrum are partly related to peroxisome impairment	13
Proteomic characterisation of polyglucosan bodies in skeletal muscle in RBCK1 deficiency	13
RAPGEF2 mediates oligomeric Aβ‐induced synaptic loss and cognitive dysfunction in the 3xTg‐AD mouse model of Alzheimer’s disease	13
The molecular landscape and associated clinical experience in infant medulloblastoma: prognostic significance of second‐generation subtypes	12
MiR‐142‐3p regulates synaptopathy‐driven disease progression in multiple sclerosis	12
DNA methylation profiling improves routine diagnosis of paediatric central nervous system tumours: A prospective population‐based study	12
Accurate calling of KIAA1549‐BRAF fusions from DNA of human brain tumours using methylation array‐based copy number and gene panel sequencing data	12
G protein‐coupled receptor kinases are associated with Alzheimer's disease pathology	12
L‐DOPA regulates α‐synuclein accumulation in experimental parkinsonism	11
CD47 promotes the proliferation and migration of adamantinomatous craniopharyngioma cells by activating the MAPK/ERK pathway, and CD47 blockade facilitates microglia‐mediated phagocytosis	11
Concomitant LATE‐NC in Alzheimer's disease is not associated with increased tau or amyloid‐β pathological burden	11
Faster disease progression in Parkinson’s disease with type 2 diabetes is not associated with increased α‐synuclein, tau, amyloid‐β or vascular pathology	11
Tumour‐associated CD204⁺ microglia/macrophages accumulate in perivascular and perinecrotic niches and correlate with an interleukin‐6‐enriched inflammatory profile in glioblastoma	11
Transcriptional signatures of synaptic vesicle genes define myotonic dystrophy type I neurodegeneration	11
Targeted next‐generation sequencing of adult gliomas for retrospective prognostic evaluation and up‐front diagnostics	11
The prognostic significance of clinicopathological features in meningiomas: Microscopic brain invasion can predict patient outcome in otherwise benign meningiomas	11
Protein homeostasis in LGMDR9 (LGMD2I) – The role of ubiquitin–proteasome and autophagy–lysosomal system	11
Global microRNA profiling identified miR‐10b‐5p as a regulator of neurofibromatosis 1 (NF1)‐glioma migration	10
Neuron types in the primate striatum: Stereological analysis of projection neurons and interneurons in control and parkinsonian monkeys	10
Sex differences in the neuropathological hallmarks of Alzheimer’s disease: focus on cognitively intact elderly individuals	10

Heterozygous APOE Christchurch in familial Alzheimer’s disease without mutations in other Mendelian genes	10
Concurrent tau pathologies in frontotemporal lobar degeneration with TDP‐43 pathology	10
Invited Review – A 5‐year update on epigenome‐wide association studies of DNA modifications in Alzheimer’s disease: progress, practicalities and promise	10
Emerging roles for the YAP/TAZ transcriptional regulators in brain tumour pathology and targeting options	10
Old age genetically confirmed frontotemporal lobar degeneration with TDP‐43 has limbic predominant TDP‐43 deposition	10
Irisin treatment lowers levels of phosphorylated tau in the hippocampus of pre‐symptomatic female but not male htau mice	10
HnRNP K mislocalisation in neurons of the dentate nucleus is a novel neuropathological feature of neurodegenerative disease and ageing	10
Arteriolar neuropathology in cerebral microvascular disease	10
BRAIN UK: Accessing NHS tissue archives for neuroscience research	9
Neuropathology of genetically defined malformations of cortical development—A systematic literature review	9
Telomeric alterations in the default mode network during the progression of Alzheimer’s disease: Selective vulnerability of the precuneus	9
Extracellular matrix remodelling is associated with muscle force increase in overloaded mouse plantaris muscle	9
Diagnostic accuracy of 1p/19q codeletion tests in oligodendroglioma: A comprehensive meta‐analysis based on a Cochrane systematic review	9
The severity of behavioural symptoms in FTD is linked to the loss of GABRQ‐expressing VENs and pyramidal neurons	9
MOBP and HIP1 in multiple system atrophy: New α‐synuclein partners in glial cytoplasmic inclusions implicated in the disease pathogenesis	9
AKT1^E17K‐mutated meningioma cell lines respond to treatment with the AKT inhibitor AZD5363	9
Post‐treatment hypermutation in a recurrent diffuse glioma with H3.3 p.G34 Mutation	9
Splicing factor proline and glutamine rich intron retention, reduced expression and aggregate formation are pathological features of amyotrophic lateral sclerosis	9
Characterisation of early ultrastructural changes in the cerebral white matter of CADASIL small vessel disease using high‐pressure freezing/freeze‐substitution	9
Seizure activity and brain damage in a model of focal non‐convulsive status epilepticus	9
ALK‐rearranged histiocytosis: Report of two cases with involvement of the central nervous system	9
Cauda equina paragangliomas express HOXB13	9
The desmin mutation R349P increases contractility and fragility of stem cell‐generated muscle micro‐tissues	9