Biochimica et Biophysica Acta-Reviews on Cancer

Article	Citations
Tumour cell-induced platelet aggregation in breast cancer: Scope of metal nanoparticles	286
The bridging role of neutrophils in the progression of inflammation-induced colorectal cancer	284
Modeling bladder cancer in the laboratory: Insights from patient-derived organoids	228
Microbial influence on triggering and treatment of host cancer: An intestinal barrier perspective	201
Targeted drug delivery systems in Lymphoma treatment: Advances and clinical perspectives	176
The role of protein glycosylation in colorectal cancer: From molecular pathways to clinical applications	127
Unlocking the power of innate lymphoid cell plasticity in the tumor microenvironment: A revolutionary pathway for cancer immunotherapy	121
Reflections on drug resistance to KRAS inhibitors and gene silencing/editing tools for targeting mutant KRAS in cancer treatment	115
Spatiotemporal dynamics of the pre-metastatic niche: remodeling of lung microenvironment before breast cancer metastasis and targeted intervention strategies	112
miRNAs and androgen deprivation therapy for prostate cancer	106
VISTA as a context-dependent immune checkpoint: Implications for tumor immunity and autoimmune pathogenesis	106
ESR1 activating mutations: From structure to clinical application	102
Is tumour-expressed aminopeptidase N (APN/CD13) structurally and functionally unique?	95
Uveal melanoma modeling in mice and zebrafish	92
TSPAN1, a novel tetraspanin member highly involved in carcinogenesis and chemoresistance	80
Advances in epigenetic modifications and cervical cancer research	78
Nutrition and dietary restrictions in cancer prevention	76
Progress and challenges of immunotherapy in triple-negative breast cancer	73
Dual perspective on autophagy in glioma: Detangling the dichotomous mechanisms of signaling pathways for therapeutic insights	71
Biomarkers in high grade serous ovarian cancer	70
Insights into the role of connexins and specialized intercellular communication pathways in breast cancer: Mechanisms and applications	66
The VEGF/VEGFR2 system in ovarian cancer: From functional to pharmacological significance	65
Exploring synthetic lethality in cancer therapy: CRISPR-Cas9 technology offers new hope	65
Transcription factors in glioblastoma – Molecular pathogenesis and clinical implications	62
Yin yang 1: a potential regulator of immune related diseases and cancer immunity	62

Epigenetic changes associated with Bacillus Calmette-Guerin (BCG) treatment in bladder cancer	60
Detection methods for mitochondrial DNA heteroplasmy and their potential single-cell applications in cancer	59
Decoding the role of FOXP3 in esophageal cancer: Underlying mechanisms and therapeutic implications	58
Contribution of CXCR3-mediated signaling in the metastatic cascade of solid malignancies	57
In what area of biology has a “new” type of cell death been discovered?	56
Extracellular vesicles in cancer therapy: Roles, potential application, and challenges	55
Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature	53
Targeting lipid metabolism in cancer metastasis	53
Unveiling anaphylatoxins: Pioneering cancer therapies through complement system insights	52
Fascin-1 in primary liver cancers, perspectives for targeted therapy	52
Revisiting CHK1 and WEE1 kinases as therapeutic targets in cancer	52
CCL20-CCR6 signaling in tumor microenvironment: Functional roles, mechanisms, and immunotherapy targeting	52
Mitochondrial metabolism in laryngeal cancer: therapeutic mechanisms and prospects	52
Long non-coding RNAs: Fundamental regulators and emerging targets of cancer stem cells	52
Advances and prospects of mRNA vaccines in cancer immunotherapy	51
Enhancing the anti-tumor response by combining DNA damage repair inhibitors in the treatment of solid tumors	50
S100A8 and S100A9 in Cancer	50
Interleukin-21 as an adjuvant in cancer immunotherapy: Current advances and future directions	49
Prognostic features of the tumour microenvironment in oesophageal adenocarcinoma	49
Inhibition of nucleotide excision repair proteins associated with cancer chemotherapy	48
Multiple impacts of Naa10p on cancer progression: Molecular functions and clinical prospects	48
Integrating multi-omics proteomic approaches in deciphering the tumor microenvironment and therapeutic resistance mechanisms in prostate cancer	47
Small non-coding RNAs and pancreatic ductal adenocarcinoma: Linking diagnosis, pathogenesis, drug resistance, and therapeutic potential	47
Mitochondrial dynamics and metabolic attributes regulate function of natural killer cell and infiltration in tumor microenvironment modulating disease progression	47
The interplay of obesity, microbiome dynamics, and innovative anti-obesity strategies in the context of endometrial cancer progression and therapeutic approaches	45
Targeting Cdc20 for cancer therapy	45
STIM1-mediated calcium signalling in cancer: Its relation to tumour aggressiveness and therapeutic horizons	45
Recent insights into RNA m5C methylation modification in hepatocellular carcinoma	45
The mechanics of anoikis resistance in cancer	44
Multifaceted roles of neutrophils in tumor microenvironment	43
Multiple therapeutic approaches of glioblastoma multiforme: From terminal to therapy	43
Targeting the triad: phenotypic plasticity, tumor microenvironment and bone microenvironment in prostate cancer bone-metastatic events	42
Olfactomedin 4 in cancer development and progression	41
Modulation of N-glycosylation in the PD-1: PD-L1 axis as a strategy to enhance cancer immunotherapies	41
Focus on mast cells in the tumor microenvironment: Current knowledge and future directions	41
In vitro anticancer properties of anthocyanins: A systematic review	40
ASPORIN: A root of the matter in tumors and their host environment	40
The Pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: Old spectacles with new insights	40
Epithelial-Mesenchymal Transition in Cancer: A Focus on Itraconazole, a Hedgehog Inhibitor	39
Targetable axes of tumor-associated macrophages: An MSF framework for precision immunotherapy	39
An overview of BAP1 biological functions and current therapeutics	39
A role for RIO kinases in the crosshair of cancer research and therapy	39
Antibody-drug conjugates in breast cancer: Marching from HER2-overexpression into HER2-low	39
Editorial Board	38
Current advances in comprehensive omics data mining for oncology and cancer research	38
Vagus innervation in the gastrointestinal tumor: Current understanding and challenges	36
Nondiploid cancer cells: Stress, tolerance and therapeutic inspirations	36
Implications of viral infection in cancer development	35
Intestinal multicellular organoids to study colorectal cancer	34
Ubiquitination/de-ubiquitination: A promising therapeutic target for PTEN reactivation in cancer	34

The NLRP3 inflammasome and its role in acute myeloid leukemia onset and development	33
Cellular functions, molecular signalings and therapeutic applications: Translational potential of deubiquitylating enzyme USP9X as a drug target in cancer treatment	33
Refinement of safety and efficacy of anti-cancer chemotherapeutics by tailoring their site-specific intracellular bioavailability through transporter modulation	33
Antibody-drug conjugates in HER-2 negative breast cancers with poor prognosis	33
Predictive and prognostic value of PIK3CA mutations in HER2-positive breast cancer treated with tyrosine kinase inhibitors: A systematic review and meta-analysis	33
Platinum-based systematic therapy in triple-negative breast cancer	32
Abnormal metabolism in hepatic stellate cells: Pandora's box of MAFLD related hepatocellular carcinoma	32
CD8+ T-cell exhaustion: Impediment to triple-negative breast cancer (TNBC) immunotherapy	32
Unveiling the potential of gene editing techniques in revolutionizing Cancer treatment: A comprehensive overview	32
Combination therapy in cancer: The potential of tetrandrine as a polytherapy for acute myeloid leukemia	32
Matrisomics: Beyond the extracellular matrix for unveiling tumor microenvironment	32
Strategies for studying immune and non-immune human and canine mammary gland cancer tumour infiltrate	31
Directing CAR T cells towards the tumor vasculature for the treatment of solid tumors	31
Muscle-to-tumor crosstalk: The effect of exercise-induced myokine on cancer progression	31
Interactions between cancer cells and tumor-associated macrophages in tumor microenvironment	31
New target DDR1: A “double-edged sword” in solid tumors	31
Advances in clinical immunotherapy for gastric cancer	31
Unveiling the TGF-β/Smad signaling in renal carcinoma progression: Prognostic and therapeutic insights	30
Overview of splicing variation in ovarian cancer	30
Exosomal non-coding RNAs (ncRNAs) as potential biomarkers in tumor early diagnosis	30
Immune archetypes TIME classification system for nasopharyngeal carcinoma: A new direction for precision immunotherapy	30
Emerging strategies to overcome PARP inhibitors' resistance in ovarian cancer	30
Taurine and cancer: Biological properties and multifaceted roles in cancer progression	30
M6A methylation in tumor immune microenvironment: Multidimensional mechanism and targeted therapy strategies	29
HOXA1, a breast cancer oncogene	29
Unraveling molecular aberrations and pioneering therapeutic strategies in osteosarcoma	29
A holistic view on c-Kit in cancer: Structure, signaling, pathophysiology and its inhibitors	29
The microbiota-m6A-metabolism axis: Implications for therapeutic strategies in gastrointestinal cancers	28
RUNX1 and cancer	28
Dual role of Snail1 as transcriptional repressor and activator	28
Exploring the gut microbiome: A potential biomarker for cancer diagnosis, prognosis, and therapy	28
Schwann cells and enteric glial cells: Emerging stars in colorectal cancer	28
Colorectal cancer: Metabolic interactions reshape the tumor microenvironment	27
Potentially diagnostic and prognostic roles of piRNAs/PIWIs in pancreatic cancer: A review	27
USP7 - a crucial regulator of cancer hallmarks	27
Carbonic anhydrase IX: An atypical target for innovative therapies in cancer	27
Research progress on the regulatory role of lactate and lactylation in tumor microenvironment	27
Metabolic insights into TAMs and the tumor immune microenvironment: Regulatory mechanisms and therapeutic interventions	27
Stress granules dynamics and promising functions in pancreatic cancer	26
A novel approach to reducing disparities in health outcomes by enhancing interpretation of cancer clinical trials for underrepresented patient groups	26
Scientific and clinical relevance of non-cellular tumor microenvironment components in ovarian cancer chemotherapy resistance	26
Dietary sugar intervention: A promising approach for cancer therapy	26
Keratin 1 as a cell-surface receptor in cancer	25
Keep your eyes peeled for long noncoding RNAs: Explaining their boundless role in cancer metastasis, drug resistance, and clinical application	25
Role of macrophage PKM2 in inflammation and tumor progression and its targeted therapy	25
Augmentation of the EPR effect by mild hyperthermia to improve nanoparticle delivery to the tumor	25
Perspectives and mechanisms for targeting mitotic catastrophe in cancer treatment	25
From resistance to resilience: Uncovering chemotherapeutic resistance mechanisms; insights from established models	25
To kill a cancer: Targeting the immune inhibitory checkpoint molecule, B7-H3	25
Role of F-box proteins in human upper gastrointestinal tumors	25
Artificial intelligence and allied subsets in early detection and preclusion of gynecological cancers	25
Interleukin-1 signaling in solid organ malignancies	25
Sequencing of antibody drug conjugates in breast cancer: Evidence gap and future directions	25
New insight into the role of SMAD4 mutation/deficiency in the prognosis and therapeutic resistance of pancreatic ductal adenocarcinomas	25
Epigenetic regulation of cancer-associated fibroblast heterogeneity	25
Proteomics of post-translational modifications in colorectal cancer: Discovery of new biomarkers	25
Corrigendum to “Snail1 as a key prognostic biomarker of cancer-associated fibroblasts in breast tumors” [Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, volume 1880 (2025) / 189316]	24
Role of Yin Yang 1 (YY1) on microenvironment, signaling pathways, and epigenetics in lung cancer	24
Expression and function of NF-Y subunits in cancer	24
Non-small cell lung cancer: Emerging molecular targeted and immunotherapeutic agents	24
Dual roles of human endogenous retroviruses in cancer progression and antitumor immune response	24
Histone deacetylase complexes: Structure, regulation and function	24
SNARE proteins: Core engines of membrane fusion in cancer	24
Advances in the combination of immunoadjuvants and tumor ablation: Mediating immune effects to enhance anti-tumor efficacy	24
Epidermal growth factor receptor PROTACs as an effective strategy for cancer therapy: A review	24
A special subtype: Revealing the potential intervention and great value of KRAS wildtype pancreatic cancer	24
The neoantigens derived from transposable elements – A hidden treasure for cancer immunotherapy	23
Radiotherapy modulates autophagy to reshape the tumor immune microenvironment to enhance anti-tumor immunity in esophageal cancer	23
Tumoral heterogeneity in neuroblastoma	23
Emerging roles of PIWI-interacting RNAs (piRNAs) and PIWI proteins in head and neck cancer and their potential clinical implications	23
Spatiotemporal heterogeneity and clinical challenge of pancreatic neuroendocrine tumors	23
Understanding the role of DNA methylation in colorectal cancer: Mechanisms, detection, and clinical significance	23
The correlation between gut and intra-tumor microbiota and PDAC: Etiology, diagnostics and therapeutics	23
The interplay between microbiome and host factors in pathogenesis and therapy of head and neck cancer	22
Psychological intervention to treat distress: An emerging frontier in cancer prevention and therapy	22
Overcoming therapeutic resistance in pancreatic cancer: Emerging opportunities by targeting BRCAs and p53	22
Editorial Board	22
Role of the intratumoral microbiome in tumor progression and therapeutics implications	22
Research progress of mitochondria and cytoskeleton crosstalk in tumour development	22
Cancer stem cells in focus: Deciphering the dynamic functional landscape of stemness in cancer	22

Reflecting on the cardiac toxicity in non-small cell lung cancer in the era of immune checkpoint inhibitors therapy combined with thoracic radiotherapy	22
Machine Learning in Epigenomics: Insights into Cancer Biology and Medicine	22
Epigenetic therapy: Research progress of decitabine in the treatment of solid tumors	21
Nanoparticulate delivery and targeting of RNA to the brain	21
Clinical considerations of CDK4/6 inhibitors in triple-negative breast cancer	21
B7-H3 regulates anti-tumor immunity and promotes tumor development in colorectal cancer	21
Unraveling metastatic timing: insights and challenges from genomic evolution	21
The signaling pathways regulated by KRAB zinc-finger proteins in cancer	21
Finding the junction between claudins and endometrial carcinoma	21
βIII-tubulin overexpression in cancer: Causes, consequences, and potential therapies	21
Anoikis and NETosis in colorectal cancer liver metastasis: the relationship and perspectives	21
CD95 (Fas) and CD95L (FasL)-mediated non-canonical signaling pathways	20
Snake venom-derived peptides as anticancer candidates: Pioneering next-generation therapies	20
A review exploring the fusion of oncolytic viruses and cancer immunotherapy: An innovative strategy in the realm of cancer treatment	20
Tumor microenvironment diversity and plasticity in cancer multidrug resistance	20
Changing landscape of anti-angiogenic therapy: Novel approaches and clinical perspectives	20
Unveiling Cuproptosis: Mechanistic insights, roles, and leading advances in oncology	20
Roles of K(H)SRP in modulating gene transcription throughout cancer progression: Insights from cellular studies to clinical perspectives	20
Molecular and immune pathobiology of human angiosarcoma	20
The potential of TRP channels as new prognostic and therapeutic targets against prostate cancer progression	20
Metabolic reprogramming in breast cancer: Pathways driving progression, drug resistance, and emerging therapeutics	19
Osteoblasts in bone metastasis: Key players in the tumor microenvironment and therapeutic targets	19
Biological function, regulatory mechanism, and clinical application of mannose in cancer	19
Comprehensive insights of etiological drivers of hepatocellular carcinoma: Fostering targeted nano delivery to anti-cancer regimes	19
Enhancing immune checkpoint blockade therapy of genitourinary malignancies by co-targeting PMN-MDSCs	19
Decoding the role of intratumoral microbiota in gastric cancer	19
Thymic epithelial tumor medical treatment: A narrative review	19
The role of TRIM25 in the occurrence and development of cancers and inflammatory diseases	19
Dietary and serum advanced glycation end-products and clinical outcomes in breast cancer	19
Cancer-associated fungi: An emerging powerful player in cancer immunotherapy	18
Editorial Board	18
Therapeutic strategies of dual-target small molecules to overcome drug resistance in cancer therapy	18
GSDM family and glioma	18
The role of exosomes in the tumour microenvironment on macrophage polarisation	18
Improving the efficacy of anti-EGFR drugs in GBM: Where we are going?	18
Clinical and Molecular Attributes and Evaluation of Pancreatic Cystic Neoplasm	18
Advances in tuft cells, a chemosensory cell in sequential diseases of the pancreas	18
Advances in glioma models using in vivo electroporation to highjack neurodevelopmental processes	18
TERT promoter mutations in gliomas: Molecular roles in tumorigenesis, metastasis, diagnosis, prognosis, therapeutic targeting, and drug resistance	18
The comparison of pathogenic role and mechanism of Kallistatin and PEDF in tumors	17
Dissecting the dual roles of lysosomal membrane proteins: Mediators of autophagy–apoptosis crosstalk in tumor progression	17
EV-mediated asymmetrical crosstalk between CAFs and cancer cells in the tumor microenvironment	17
Interstitial fluid pressure as an emerging biomarker in solid tumors	17
Sensory neuro-tumor crosstalk: Therapeutic opportunities and emerging frontiers in cancer neuroscience	17
Epigenetic mechanisms of cancer progression and therapy resistance in estrogen-receptor (ER+) breast cancer	17
Odors and cancer: Current status and future directions	17
Cyclin-dependent kinases in DNA damage response	17
Precision medicine and phosphoproteomics for the identification of novel targeted therapeutic avenues in sarcomas	17
Protein induced by vitamin K absence or antagonist II: Experience to date and future directions	17