Biochimica et Biophysica Acta-Reviews on Cancer

Article	Citations
Immunotherapy for HPV negative head and neck squamous cell carcinoma	308
SENP3: Cancers and diseases	223
Clinical and molecular markers guide the genetics of pheochromocytoma and paraganglioma	211
PAK2 as a therapeutic target in cancer: Mechanisms, challenges, and future perspectives	209
Research progress of mitochondria and cytoskeleton crosstalk in tumour development	184
Adipose tissue-to-breast cancer crosstalk: Comprehensive insights	130
The neoantigens derived from transposable elements – A hidden treasure for cancer immunotherapy	129
A comprehensive review of current therapeutic strategies in cancers targeting DNA damage response mechanisms in head and neck squamous cell cancer	109
New horizons in the mechanisms and therapeutic strategies for PD-L1 protein degradation in cancer	105
Retraction notice to “Coagulation and inflammation in cancer: Limitations and prospects for treatment” [Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877 (2022) 188727]	101
Glioblastoma preclinical models: Strengths and weaknesses	93
The microbiota and aging microenvironment in pancreatic cancer: Cell origin and fate	88
Editorial Board	88
Emerging roles of PIWI-interacting RNAs (piRNAs) and PIWI proteins in head and neck cancer and their potential clinical implications	87
Extrachromosomal DNA: Redefining the pathogenesis of glioblastoma	82
Exploration of tumor penetrating peptide iRGD as a potential strategy to enhance tumor penetration of cancer nanotherapeutics	75
Ponatinib: An update on its drug targets, therapeutic potential and safety	75
Editorial Board	71
Microbial influence on triggering and treatment of host cancer: An intestinal barrier perspective	70
Cancer stem cell in prostate cancer progression, metastasis and therapy resistance	69
Spatiotemporal heterogeneity and clinical challenge of pancreatic neuroendocrine tumors	66
Editorial Board	63
Radiolabeled nanobodies for tumor targeting: From bioengineering to imaging and therapy	59
Tumor microenvironment crosstalk between tumors and the nervous system in pancreatic cancer: Molecular mechanisms and clinical perspectives	58
Adenosine in cancer immunotherapy: Taking off on a new plane	57

Lymphatic vasculature in ovarian cancer	55
Topical advances in PIM kinases and their inhibitors: Medicinal chemistry perspectives	54
An insight into the ubiquitin-proteasomal axis and related therapeutic approaches towards central nervous system malignancies	53
Epithelial-mesenchymal transition: When tumor cells meet myeloid-derived suppressor cells	52
Tumoral heterogeneity in neuroblastoma	50
The naked translation in cancer	49
Non-small cell lung cancer: Emerging molecular targeted and immunotherapeutic agents	49
Time to abandon CAR-T monotherapy for solid tumors	45
Reinforcing the immunogenic cell death to enhance cancer immunotherapy efficacy	43
New insights into RAS in head and neck cancer	43
The high-grade serous ovarian cancer metastasis and chemoresistance in 3D models	43
Reflecting on the cardiac toxicity in non-small cell lung cancer in the era of immune checkpoint inhibitors therapy combined with thoracic radiotherapy	43
TSPAN1, a novel tetraspanin member highly involved in carcinogenesis and chemoresistance	42
GPX4: The hub of lipid oxidation, ferroptosis, disease and treatment	41
New insights into exosome mediated tumor-immune escape: Clinical perspectives and therapeutic strategies	41
Targeting nanoparticles to malignant tumors	38
Advances in epigenetic modifications and cervical cancer research	37
The application of CA72-4 in the diagnosis, prognosis, and treatment of gastric cancer	37
The clinical significance and correlative signaling pathways of paired box gene 9 in development and carcinogenesis	37
Advances and challenges in therapeutic resistant biomarkers of neuroblastoma: A comprehensive review	36
Machine Learning in Epigenomics: Insights into Cancer Biology and Medicine	36
Decoding secret role of mesenchymal stem cells in regulating cancer stem cells and drug resistance	36
Recent advances in understanding the molecular role of phosphoinositide-specific phospholipase C gamma 1 as an emerging onco-driver and novel therapeutic target in human carcinogenesis	35
The role of the NDRG1 in the pathogenesis and treatment of breast cancer	35
New advances in the therapeutic strategy of head and neck squamous cell carcinoma: A review of latest therapies and cutting-edge research	35
Is tumour-expressed aminopeptidase N (APN/CD13) structurally and functionally unique?	35
Overcoming therapeutic resistance in pancreatic cancer: Emerging opportunities by targeting BRCAs and p53	34
Nutrition and dietary restrictions in cancer prevention	34
ETS transcription factors: Multifaceted players from cancer progression to tumor immunity	34
Modulating the gut microbiota by probiotics, prebiotics, postbiotics, and fecal microbiota transplantation: An emerging trend in cancer patient care	34
Hurdle or thruster: Glucose metabolism of T cells in anti-tumour immunity	33
T cell exhaustion in human cancers	32
The potential of methioninase for cancer treatment	32
Genomic instability, inflammatory signaling and response to cancer immunotherapy	31
The role of m6A modification in pediatric cancer	31
A special subtype: Revealing the potential intervention and great value of KRAS wildtype pancreatic cancer	31
A Darwinian perspective on tumor immune evasion	31
The role of 5-HT metabolism in cancer	30
RNA m6A modification in prostate cancer: A new weapon for its diagnosis and therapy	29
ESR1 activating mutations: From structure to clinical application	29
Epidermal growth factor receptor PROTACs as an effective strategy for cancer therapy: A review	29
Targeting protein kinases benefits cancer immunotherapy	29
The overall process of metastasis: From initiation to a new tumor	28
The correlation between gut and intra-tumor microbiota and PDAC: Etiology, diagnostics and therapeutics	28
Expression and function of NF-Y subunits in cancer	27
Unlocking the potential: Targeting metabolic pathways in the tumor microenvironment for Cancer therapy	27
N6-methyladenosine RNA modification in PD-1/PD-L1: Novel implications for immunotherapy	27
The role of nitric oxide synthase/ nitric oxide in infection-related cancers: Beyond antimicrobial activity	27
Understanding the role of DNA methylation in colorectal cancer: Mechanisms, detection, and clinical significance	27
Structure, function, signaling pathways and clinical therapeutics: The translational potential of STAT3 as a target for cancer therapy	27

Histone deacetylase complexes: Structure, regulation and function	26
Macrophages and tertiary lymphoid structures as indicators of prognosis and therapeutic response in cancer patients	26
Targeting autophagy in urological system cancers: From underlying mechanisms to therapeutic implications	25
Drivers of cancer metastasis – Arise early and remain present	25
The interaction of SET and protein phosphatase 2A as target for cancer therapy	25
Modeling bladder cancer in the laboratory: Insights from patient-derived organoids	25
Decoding PTEN regulation in clear cell renal cell carcinoma: Pathway for biomarker discovery and therapeutic insights	25
Mitochondria: The metabolic switch of cellular oncogenic transformation	24
Combinatorial therapy in tumor microenvironment: Where do we stand?	24
Proprotein convertase subtilisin/kexin type 9 (PCSK9): A potential multifaceted player in cancer	24
Mitochondrial dynamics, a new therapeutic target for Triple Negative Breast Cancer	24
Dual roles of human endogenous retroviruses in cancer progression and antitumor immune response	24
Delivery routes matter: Safety and efficacy of intratumoral immunotherapy	24
The ubiquitin-proteasome system in the regulation of tumor dormancy and recurrence	23
Improving DCIS diagnosis and predictive outcome by applying artificial intelligence	23
Ezrin gone rogue in cancer progression and metastasis: An enticing therapeutic target	23
A digital highway for data fluidity and data equity in precision medicine	23
Targeting the heat shock response induced by modulated electro-hyperthermia (mEHT) in cancer	23
Metastasis prevention: How to catch metastatic seeds	22
miRNAs and androgen deprivation therapy for prostate cancer	22
Reflections on drug resistance to KRAS inhibitors and gene silencing/editing tools for targeting mutant KRAS in cancer treatment	22
Exosomes at the crossroad between therapeutic targets and therapy resistance in head and neck squamous cell carcinoma	22
An overview of the research progress of BRCA gene mutations in breast cancer	22
Uveal melanoma modeling in mice and zebrafish	22
Understanding and advancement in gold nanoparticle targeted photothermal therapy of cancer	22
The RNA m6A writer METTL14 in cancers: Roles, structures, and applications	21
Editorial Board	21
Protein domain-based approaches for the identification and prioritization of therapeutically actionable cancer variants	21
Targeting ion channels for the treatment of lung cancer	21
Adenoid cystic carcinoma: a review of clinical features, treatment targets and advances in improving the immune response to monoclonal antibody therapy	21
Editorial Board	21
Progress and challenges of immunotherapy in triple-negative breast cancer	21
The tumor microenvironment's gambit: Exosomal pawns on the board of head and neck cancer	21
B7-H3 regulates anti-tumor immunity and promotes tumor development in colorectal cancer	21
The roles of small extracellular vesicles in lung cancer: Molecular pathology, mechanisms, diagnostics, and therapeutics	20
An overview of kinin mediated events in cancer progression and therapeutic applications	20
S100A8 and S100A9 in Cancer	20
Oncoviruses: How do they hijack their host and current treatment regimes	20
Editorial Board	20
Clinical considerations of CDK4/6 inhibitors in triple-negative breast cancer	20
Vitamin K: New insights related to senescence and cancer metastasis	20
Recent advances in HDAC-targeted imaging probes for cancer detection	20
Multiplex immunohistochemistry of metastatic colorectal cancer and ex vivo tumor avatars	20
Targeting Trop-2 in cancer: Recent research progress and clinical application	20
Tumor draining lymph nodes, immune response, and radiotherapy: Towards a revisal of therapeutic principles	20
Editorial Board	19
Dissecting SOX2 expression and function reveals an association with multiple signaling pathways during embryonic development and in cancer progression	19
Find the path of least resistance: Adaptive therapy to delay treatment failure and improve outcomes	19
Regulation of cGAS-STING signalling in cancer: Approach for combination therapy	19
Impact of hereditary thrombophilia on cancer-associated thrombosis, tumour susceptibility and progression: A review of existing evidence	19
The intratumoural microbiota in cancer: new insights from inside	19
Apoptosis, necroptosis, and pyroptosis as alternative cell death pathways induced by chemotherapeutic agents?	19
Helicobacter pylori triggers inflammation and oncogenic transformation by perturbing the immune microenvironment	19
Lactic acid: The culprit behind the immunosuppressive microenvironment in hepatocellular carcinoma	19
Elucidating the mechanisms of Temozolomide resistance in gliomas and the strategies to overcome the resistance.	19
Advances in nuclei targeted delivery of nanoparticles for the management of cancer	19
Transcription factors in glioblastoma – Molecular pathogenesis and clinical implications	19
Tumor-associated neutrophils and neutrophil-targeted cancer therapies	19
CDK7-dependent transcriptional addiction in bone and soft tissue sarcomas: Present and Future	19
Role of exosomes in lung cancer: A comprehensive insight from immunomodulation to theragnostic applications	19
Leveraging preclinical models of metastatic breast cancer	18
Roles of CDK12 mutations in PCa development and treatment	18
Targeting endothelial cell anergy to improve CAR T cell therapy for solid tumors	18
Role of cell division cycle-associated proteins in regulating cell cycle and promoting tumor progression	18
Promises of natural products as clinical applications for cancer	18
How to evaluate deep learning for cancer diagnostics – factors and recommendations	17
Epigenetic therapy: Research progress of decitabine in the treatment of solid tumors	17
Precision oncology: Using cancer genomics for targeted therapy advancements	17
Paradoxical functions of long noncoding RNAs in modulating STAT3 signaling pathway in hepatocellular carcinoma	17
Corrigendum to “Recent thymic emigrants as the bridge between thymoma and autoimmune diseases” [Biochim Biophys Acta Rev Cancer. 2022;1877(3):188730.]	17
Targeting the MHC-I endosomal-lysosomal trafficking pathway in cancer: From mechanism to immunotherapy	17
Decoding mitochondria's role in immunity and cancer therapy	17
Snail transcription factors as key regulators of chemoresistance, stemness and metastasis of ovarian cancer cells	17
Tumor microenvironment of human breast cancer, and feline mammary carcinoma as a potential study model	16
Long non-coding RNAs and cancer metastasis: Molecular basis and therapeutic implications	16
Targeting Bcl-2 for cancer therapy	16
RORγT agonists as immune modulators in anticancer therapy.	16
Advances in immunotherapy for breast cancer and feline mammary carcinoma: From molecular basis to novel therapeutic targets	15
Breaking through therapeutic barriers: Insights into CDK4/6 inhibition resistance in hormone receptor-positive metastatic breast cancer	15
PARP inhibitor resistance in ovarian cancer: Underlying mechanisms and therapeutic approaches targeting the ATR/CHK1 pathway	15

Oncosuppressive and oncogenic activity of the sphingolipid-metabolizing enzyme β-galactosylceramidase	15
CD95 (Fas) and CD95L (FasL)-mediated non-canonical signaling pathways	15
Contribution of CXCR3-mediated signaling in the metastatic cascade of solid malignancies	15
Ability of animals to detect cancer odors	15
Targeting tumor and bone microenvironment: Novel therapeutic opportunities for castration-resistant prostate cancer patients with bone metastasis	15
Targeting DNA damage response in pancreatic ductal adenocarcinoma: A review of preclinical and clinical evidence	15
Finding the junction between claudins and endometrial carcinoma	15
Keep a watchful eye on methionine adenosyltransferases, novel therapeutic opportunities for hepatobiliary and pancreatic tumours	15
The potential roles of p53 signaling reactivation in pancreatic cancer therapy	15