Biochimica et Biophysica Acta-Reviews on Cancer

Article	Citations
A digital highway for data fluidity and data equity in precision medicine	262
Histone deacetylase complexes: Structure, regulation and function	213
Macrophages and tertiary lymphoid structures as indicators of prognosis and therapeutic response in cancer patients	194
PAK2 as a therapeutic target in cancer: Mechanisms, challenges, and future perspectives	190
Research progress of mitochondria and cytoskeleton crosstalk in tumour development	173
Immunotherapy for HPV negative head and neck squamous cell carcinoma	130
SENP3: Cancers and diseases	129
The role of nitric oxide synthase/ nitric oxide in infection-related cancers: Beyond antimicrobial activity	105
Clinical and molecular markers guide the genetics of pheochromocytoma and paraganglioma	103
Decoding PTEN regulation in clear cell renal cell carcinoma: Pathway for biomarker discovery and therapeutic insights	101
New horizons in the mechanisms and therapeutic strategies for PD-L1 protein degradation in cancer	87
Unlocking the potential: Targeting metabolic pathways in the tumor microenvironment for Cancer therapy	81
T cell exhaustion in human cancers	77
The neoantigens derived from transposable elements – A hidden treasure for cancer immunotherapy	77
New advances in the therapeutic strategy of head and neck squamous cell carcinoma: A review of latest therapies and cutting-edge research	76
A comprehensive review of current therapeutic strategies in cancers targeting DNA damage response mechanisms in head and neck squamous cell cancer	75
Retraction notice to “Coagulation and inflammation in cancer: Limitations and prospects for treatment” [Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877 (2022) 188727]	75
Adipose tissue-to-breast cancer crosstalk: Comprehensive insights	69
A Darwinian perspective on tumor immune evasion	65
Editorial Board	61
Reflecting on the cardiac toxicity in non-small cell lung cancer in the era of immune checkpoint inhibitors therapy combined with thoracic radiotherapy	58
The microbiota and aging microenvironment in pancreatic cancer: Cell origin and fate	58
The role of m6A modification in pediatric cancer	57
Machine Learning in Epigenomics: Insights into Cancer Biology and Medicine	54
Emerging roles of PIWI-interacting RNAs (piRNAs) and PIWI proteins in head and neck cancer and their potential clinical implications	53

Improving DCIS diagnosis and predictive outcome by applying artificial intelligence	52
Extrachromosomal DNA: Redefining the pathogenesis of glioblastoma	49
Ponatinib: An update on its drug targets, therapeutic potential and safety	49
Ezrin gone rogue in cancer progression and metastasis: An enticing therapeutic target	46
The potential of methioninase for cancer treatment	46
A special subtype: Revealing the potential intervention and great value of KRAS wildtype pancreatic cancer	44
Microbial influence on triggering and treatment of host cancer: An intestinal barrier perspective	42
Editorial Board	42
Mitochondrial dynamics, a new therapeutic target for Triple Negative Breast Cancer	41
Cancer stem cell in prostate cancer progression, metastasis and therapy resistance	41
Spatiotemporal heterogeneity and clinical challenge of pancreatic neuroendocrine tumors	40
Recent advances in understanding the molecular role of phosphoinositide-specific phospholipase C gamma 1 as an emerging onco-driver and novel therapeutic target in human carcinogenesis	40
Is tumour-expressed aminopeptidase N (APN/CD13) structurally and functionally unique?	39
The correlation between gut and intra-tumor microbiota and PDAC: Etiology, diagnostics and therapeutics	38
Targeting protein kinases benefits cancer immunotherapy	38
Editorial Board	37
Glioblastoma preclinical models: Strengths and weaknesses	37
Exploration of tumor penetrating peptide iRGD as a potential strategy to enhance tumor penetration of cancer nanotherapeutics	37
Radiolabeled nanobodies for tumor targeting: From bioengineering to imaging and therapy	36
Tumor microenvironment crosstalk between tumors and the nervous system in pancreatic cancer: Molecular mechanisms and clinical perspectives	35
Adenosine in cancer immunotherapy: Taking off on a new plane	35
Epidermal growth factor receptor PROTACs as an effective strategy for cancer therapy: A review	34
Targeting the heat shock response induced by modulated electro-hyperthermia (mEHT) in cancer	34
RNA m6A modification in prostate cancer: A new weapon for its diagnosis and therapy	33
Overcoming therapeutic resistance in pancreatic cancer: Emerging opportunities by targeting BRCAs and p53	32
Nutrition and dietary restrictions in cancer prevention	32
An overview of the research progress of BRCA gene mutations in breast cancer	32
Lymphatic vasculature in ovarian cancer	32
Targeting nanoparticles to malignant tumors	31
An insight into the ubiquitin-proteasomal axis and related therapeutic approaches towards central nervous system malignancies	31
The application of CA72-4 in the diagnosis, prognosis, and treatment of gastric cancer	31
Proprotein convertase subtilisin/kexin type 9 (PCSK9): A potential multifaceted player in cancer	31
Topical advances in PIM kinases and their inhibitors: Medicinal chemistry perspectives	31
The clinical significance and correlative signaling pathways of paired box gene 9 in development and carcinogenesis	29
Tumoral heterogeneity in neuroblastoma	29
Non-small cell lung cancer: Emerging molecular targeted and immunotherapeutic agents	28
The naked translation in cancer	28
New insights into RAS in head and neck cancer	27
ETS transcription factors: Multifaceted players from cancer progression to tumor immunity	27
Time to abandon CAR-T monotherapy for solid tumors	27
The role of 5-HT metabolism in cancer	27
Drivers of cancer metastasis – Arise early and remain present	27
TSPAN1, a novel tetraspanin member highly involved in carcinogenesis and chemoresistance	26
Expression and function of NF-Y subunits in cancer	26
Metastasis prevention: How to catch metastatic seeds	26
Uveal melanoma modeling in mice and zebrafish	26
New insights into exosome mediated tumor-immune escape: Clinical perspectives and therapeutic strategies	26
Epithelial-mesenchymal transition: When tumor cells meet myeloid-derived suppressor cells	25
N6-methyladenosine RNA modification in PD-1/PD-L1: Novel implications for immunotherapy	25
ESR1 activating mutations: From structure to clinical application	25

GPX4: The hub of lipid oxidation, ferroptosis, disease and treatment	25
The high-grade serous ovarian cancer metastasis and chemoresistance in 3D models	24
Modulating the gut microbiota by probiotics, prebiotics, postbiotics, and fecal microbiota transplantation: An emerging trend in cancer patient care	24
Delivery routes matter: Safety and efficacy of intratumoral immunotherapy	24
Reinforcing the immunogenic cell death to enhance cancer immunotherapy efficacy	24
Understanding the role of DNA methylation in colorectal cancer: Mechanisms, detection, and clinical significance	24
Combinatorial therapy in tumor microenvironment: Where do we stand?	23
Mitochondria: The metabolic switch of cellular oncogenic transformation	23
Understanding and advancement in gold nanoparticle targeted photothermal therapy of cancer	23
Advances in epigenetic modifications and cervical cancer research	23
Reflections on drug resistance to KRAS inhibitors and gene silencing/editing tools for targeting mutant KRAS in cancer treatment	23
Genomic instability, inflammatory signaling and response to cancer immunotherapy	22
miRNAs and androgen deprivation therapy for prostate cancer	22
Progress and challenges of immunotherapy in triple-negative breast cancer	22
Exosomes at the crossroad between therapeutic targets and therapy resistance in head and neck squamous cell carcinoma	22
Hurdle or thruster: Glucose metabolism of T cells in anti-tumour immunity	22
Targeting ion channels for the treatment of lung cancer	22
The RNA m6A writer METTL14 in cancers: Roles, structures, and applications	21
Adenoid cystic carcinoma: a review of clinical features, treatment targets and advances in improving the immune response to monoclonal antibody therapy	21
The role of the NDRG1 in the pathogenesis and treatment of breast cancer	21
The overall process of metastasis: From initiation to a new tumor	21
Dual roles of human endogenous retroviruses in cancer progression and antitumor immune response	20
Structure, function, signaling pathways and clinical therapeutics: The translational potential of STAT3 as a target for cancer therapy	20
Modeling bladder cancer in the laboratory: Insights from patient-derived organoids	20
The ubiquitin-proteasome system in the regulation of tumor dormancy and recurrence	20
Decoding secret role of mesenchymal stem cells in regulating cancer stem cells and drug resistance	20
Advances and challenges in therapeutic resistant biomarkers of neuroblastoma: A comprehensive review	20
The interaction of SET and protein phosphatase 2A as target for cancer therapy	20
The tumor microenvironment's gambit: Exosomal pawns on the board of head and neck cancer	19
Editorial Board	19
Contribution of CXCR3-mediated signaling in the metastatic cascade of solid malignancies	19
Recent advances in HDAC-targeted imaging probes for cancer detection	19
RORγT agonists as immune modulators in anticancer therapy.	19
Targeting autophagy in urological system cancers: From underlying mechanisms to therapeutic implications	19
Editorial Board	19
B7-H3 regulates anti-tumor immunity and promotes tumor development in colorectal cancer	19
Tumor microenvironment of human breast cancer, and feline mammary carcinoma as a potential study model	19
Clinical considerations of CDK4/6 inhibitors in triple-negative breast cancer	19
The O-GlcNAcylation and its promotion to hepatocellular carcinoma	19
Advances and prospects of mRNA vaccines in cancer immunotherapy	19
Protein domain-based approaches for the identification and prioritization of therapeutically actionable cancer variants	19
Clusterin as modulator of carcinogenesis: A potential avenue for targeted cancer therapy	19
Core services that power AI-driven transformation in cancer research and care	19
Editorial Board	19
Multiplex immunohistochemistry of metastatic colorectal cancer and ex vivo tumor avatars	19
Centrosome amplification in cancer and cancer-associated human diseases	18
An overview of kinin mediated events in cancer progression and therapeutic applications	18
Oncoviruses: How do they hijack their host and current treatment regimes	18
The roles of small extracellular vesicles in lung cancer: Molecular pathology, mechanisms, diagnostics, and therapeutics	18
Tumor draining lymph nodes, immune response, and radiotherapy: Towards a revisal of therapeutic principles	17
Vitamin K: New insights related to senescence and cancer metastasis	17
ROS: A “booster” for chronic inflammation and tumor metastasis	17
Role of exosomes in lung cancer: A comprehensive insight from immunomodulation to theragnostic applications	17
Oncogenic Neuregulin 1 gene (NRG1) fusions in cancer: A potential new therapeutic opportunities	17
S100A8 and S100A9 in Cancer	17
Ability of animals to detect cancer odors	17
The signaling pathways regulated by KRAB zinc-finger proteins in cancer	17
Targeting Trop-2 in cancer: Recent research progress and clinical application	17
Impact of hereditary thrombophilia on cancer-associated thrombosis, tumour susceptibility and progression: A review of existing evidence	16
Finding the junction between claudins and endometrial carcinoma	16
Activity and resistance to KRASG12C inhibitors in non-small cell lung cancer and colorectal cancer	16
Advances in nuclei targeted delivery of nanoparticles for the management of cancer	16
Targeting glutamine metabolism crosstalk with tumor immune response	16
Editorial Board	16
Find the path of least resistance: Adaptive therapy to delay treatment failure and improve outcomes	16
Insights into the role of connexins and specialized intercellular communication pathways in breast cancer: Mechanisms and applications	16
Dual perspective on autophagy in glioma: Detangling the dichotomous mechanisms of signaling pathways for therapeutic insights	15
Targeting endothelial cell anergy to improve CAR T cell therapy for solid tumors	15
Lactic acid: The culprit behind the immunosuppressive microenvironment in hepatocellular carcinoma	15
Dissecting SOX2 expression and function reveals an association with multiple signaling pathways during embryonic development and in cancer progression	15
Role of cell division cycle-associated proteins in regulating cell cycle and promoting tumor progression	15
Helicobacter pylori triggers inflammation and oncogenic transformation by perturbing the immune microenvironment	15
Leveraging preclinical models of metastatic breast cancer	15
RLIP: A necessary transporter protein for translating oxidative stress into pro-obesity and pro-carcinogenic signaling	14
Mitochondrial DNA-activated cGAS-STING pathway in cancer: Mechanisms and therapeutic implications	14
Advances in immunotherapy for breast cancer and feline mammary carcinoma: From molecular basis to novel therapeutic targets	14
Precision oncology: Using cancer genomics for targeted therapy advancements	14
YAP and TAZ: Monocorial and bicorial transcriptional co-activators in human cancers	14
Epigenetic therapy: Research progress of decitabine in the treatment of solid tumors	14
Epigenetic changes associated with Bacillus Calmette-Guerin (BCG) treatment in bladder cancer	14

Breaking through therapeutic barriers: Insights into CDK4/6 inhibition resistance in hormone receptor-positive metastatic breast cancer	14
Promises of natural products as clinical applications for cancer	14
Corrigendum to “Recent thymic emigrants as the bridge between thymoma and autoimmune diseases” [Biochim Biophys Acta Rev Cancer. 2022;1877(3):188730.]	14
Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature	14
Roles of CDK12 mutations in PCa development and treatment	14
Targeting the MHC-I endosomal-lysosomal trafficking pathway in cancer: From mechanism to immunotherapy	14
Snail transcription factors as key regulators of chemoresistance, stemness and metastasis of ovarian cancer cells	14
TRDMT1-mediated RNA C-5 methylation as a novel target in anticancer therapy	14