Biochimica et Biophysica Acta-Reviews on Cancer

Article	Citations
Tumour cell-induced platelet aggregation in breast cancer: Scope of metal nanoparticles	360
Microbial influence on triggering and treatment of host cancer: An intestinal barrier perspective	244
Is tumour-expressed aminopeptidase N (APN/CD13) structurally and functionally unique?	178
Advances in epigenetic modifications and cervical cancer research	160
Modeling bladder cancer in the laboratory: Insights from patient-derived organoids	152
TSPAN1, a novel tetraspanin member highly involved in carcinogenesis and chemoresistance	148
miRNAs and androgen deprivation therapy for prostate cancer	121
The interaction of SET and protein phosphatase 2A as target for cancer therapy	101
Nutrition and dietary restrictions in cancer prevention	100
Reflections on drug resistance to KRAS inhibitors and gene silencing/editing tools for targeting mutant KRAS in cancer treatment	97
Uveal melanoma modeling in mice and zebrafish	91
ESR1 activating mutations: From structure to clinical application	89
Progress and challenges of immunotherapy in triple-negative breast cancer	85
Decoding the role of FOXP3 in esophageal cancer: Underlying mechanisms and therapeutic implications	76
Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature	75
Targeting lipid metabolism in cancer metastasis	71
Transcription factors in glioblastoma – Molecular pathogenesis and clinical implications	68
In what area of biology has a “new” type of cell death been discovered?	67
Extracellular vesicles in cancer therapy: Roles, potential application, and challenges	65
Dual perspective on autophagy in glioma: Detangling the dichotomous mechanisms of signaling pathways for therapeutic insights	60
Insights into the role of connexins and specialized intercellular communication pathways in breast cancer: Mechanisms and applications	60
Epigenetic changes associated with Bacillus Calmette-Guerin (BCG) treatment in bladder cancer	60
Contribution of CXCR3-mediated signaling in the metastatic cascade of solid malignancies	55
Biomarkers in high grade serous ovarian cancer	54
S100A8 and S100A9 in Cancer	52

Long non-coding RNAs: Fundamental regulators and emerging targets of cancer stem cells	50
Advances and prospects of mRNA vaccines in cancer immunotherapy	49
Mitochondrial metabolism in laryngeal cancer: Therapeutic mechanisms and prospects	48
Tumor suppressor p53: Biology, signaling pathways, and therapeutic targeting	46
Enhancing the anti-tumor response by combining DNA damage repair inhibitors in the treatment of solid tumors	45
Prognostic features of the tumour microenvironment in oesophageal adenocarcinoma	45
The interplay of obesity, microbiome dynamics, and innovative anti-obesity strategies in the context of endometrial cancer progression and therapeutic approaches	45
Multiple therapeutic approaches of glioblastoma multiforme: From terminal to therapy	45
Targeting Cdc20 for cancer therapy	44
Recent insights into RNA m5C methylation modification in hepatocellular carcinoma	44
Multifaceted roles of neutrophils in tumor microenvironment	44
Small non-coding RNAs and pancreatic ductal adenocarcinoma: Linking diagnosis, pathogenesis, drug resistance, and therapeutic potential	43
Interleukin-21 as an adjuvant in cancer immunotherapy: Current advances and future directions	42
Long non-coding RNAs: A view to kill ovarian cancer	42
Multiple impacts of Naa10p on cancer progression: Molecular functions and clinical prospects	42
Editorial Board	41
Modulation of N-glycosylation in the PD-1: PD-L1 axis as a strategy to enhance cancer immunotherapies	40
Epithelial-Mesenchymal Transition in Cancer: A Focus on Itraconazole, a Hedgehog Inhibitor	40
An overview of BAP1 biological functions and current therapeutics	39
Nondiploid cancer cells: Stress, tolerance and therapeutic inspirations	39
Matrisomics: Beyond the extracellular matrix for unveiling tumor microenvironment	38
Predictive and prognostic value of PIK3CA mutations in HER2-positive breast cancer treated with tyrosine kinase inhibitors: A systematic review and meta-analysis	38
Current advances in comprehensive omics data mining for oncology and cancer research	38
Antibody-drug conjugates in HER-2 negative breast cancers with poor prognosis	38
Vagus innervation in the gastrointestinal tumor: Current understanding and challenges	38
Abnormal metabolism in hepatic stellate cells: Pandora's box of MAFLD related hepatocellular carcinoma	37
Intestinal multicellular organoids to study colorectal cancer	36
Refinement of safety and efficacy of anti-cancer chemotherapeutics by tailoring their site-specific intracellular bioavailability through transporter modulation	36
Antibody-drug conjugates in breast cancer: Marching from HER2-overexpression into HER2-low	36
CD8+ T-cell exhaustion: Impediment to triple-negative breast cancer (TNBC) immunotherapy	35
The Pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: Old spectacles with new insights	34
Cross talk between autophagy and oncogenic signaling pathways and implications for cancer therapy	34
Ubiquitination/de-ubiquitination: A promising therapeutic target for PTEN reactivation in cancer	34
In vitro anticancer properties of anthocyanins: A systematic review	34
Implications of viral infection in cancer development	34
Mesenchymal stem cells in glioblastoma therapy and progression: How one cell does it all	34
Cellular functions, molecular signalings and therapeutic applications: Translational potential of deubiquitylating enzyme USP9X as a drug target in cancer treatment	33
Focus on mast cells in the tumor microenvironment: Current knowledge and future directions	33
ASPORIN: A root of the matter in tumors and their host environment	33
Unveiling the potential of gene editing techniques in revolutionizing Cancer treatment: A comprehensive overview	31
The emerging roles of dual-specificity phosphatases and their specific characteristics in human cancer	31
A role for RIO kinases in the crosshair of cancer research and therapy	31
Platinum-based systematic therapy in triple-negative breast cancer	31
Muscle-to-tumor crosstalk: The effect of exercise-induced myokine on cancer progression	30
Advances in clinical immunotherapy for gastric cancer	30
Exploring the gut microbiome: A potential biomarker for cancer diagnosis, prognosis, and therapy	29
Overview of splicing variation in ovarian cancer	29
Unraveling molecular aberrations and pioneering therapeutic strategies in osteosarcoma	29
Exosomal non-coding RNAs (ncRNAs) as potential biomarkers in tumor early diagnosis	29
HOXA1, a breast cancer oncogene	29

Schwann cells and enteric glial cells: Emerging stars in colorectal cancer	29
Strategies for studying immune and non-immune human and canine mammary gland cancer tumour infiltrate	28
New target DDR1: A “double-edged sword” in solid tumors	28
Colorectal cancer: Metabolic interactions reshape the tumor microenvironment	28
Emerging strategies to overcome PARP inhibitors' resistance in ovarian cancer	28
Dual role of Snail1 as transcriptional repressor and activator	28
Manipulating macrophage polarization in cancer patients: From nanoparticles to human chimeric antigen receptor macrophages	28
Role of F-box proteins in human upper gastrointestinal tumors	27
Directing CAR T cells towards the tumor vasculature for the treatment of solid tumors	27
USP7 - a crucial regulator of cancer hallmarks	27
Carbonic anhydrase IX: An atypical target for innovative therapies in cancer	27
A holistic view on c-Kit in cancer: Structure, signaling, pathophysiology and its inhibitors	27
RUNX1 and cancer	27
A novel approach to reducing disparities in health outcomes by enhancing interpretation of cancer clinical trials for underrepresented patient groups	27
Research progress on the regulatory role of lactate and lactylation in tumor microenvironment	27
Potentially diagnostic and prognostic roles of piRNAs/PIWIs in pancreatic cancer: A review	26
Data-driven approaches to advance research and clinical care for pediatric cancer	26
Stress granules dynamics and promising functions in pancreatic cancer	26
SNARE proteins: Core engines of membrane fusion in cancer	26
Proteomics of post-translational modifications in colorectal cancer: Discovery of new biomarkers	26
Interleukin-1 signaling in solid organ malignancies	26
Perspectives and mechanisms for targeting mitotic catastrophe in cancer treatment	25
Scientific and clinical relevance of non-cellular tumor microenvironment components in ovarian cancer chemotherapy resistance	25
Epigenetic regulation of cancer-associated fibroblast heterogeneity	25
From resistance to resilience: Uncovering chemotherapeutic resistance mechanisms; insights from established models	25
Keep your eyes peeled for long noncoding RNAs: Explaining their boundless role in cancer metastasis, drug resistance, and clinical application	25
Artificial intelligence and allied subsets in early detection and preclusion of gynecological cancers	25
To kill a cancer: Targeting the immune inhibitory checkpoint molecule, B7-H3	25
New insight into the role of SMAD4 mutation/deficiency in the prognosis and therapeutic resistance of pancreatic ductal adenocarcinomas	24
Augmentation of the EPR effect by mild hyperthermia to improve nanoparticle delivery to the tumor	24
Keratin 1 as a cell-surface receptor in cancer	23
The clinical significance and correlative signaling pathways of paired box gene 9 in development and carcinogenesis	23
Emerging roles of PIWI-interacting RNAs (piRNAs) and PIWI proteins in head and neck cancer and their potential clinical implications	23
A digital highway for data fluidity and data equity in precision medicine	23
Consequence of distinctive expression of MUC2 in colorectal cancers: How much is actually bad?	23
A special subtype: Revealing the potential intervention and great value of KRAS wildtype pancreatic cancer	23
Histone deacetylase complexes: Structure, regulation and function	22
Improving DCIS diagnosis and predictive outcome by applying artificial intelligence	22
Expression and function of NF-Y subunits in cancer	22
The correlation between gut and intra-tumor microbiota and PDAC: Etiology, diagnostics and therapeutics	22
Overcoming therapeutic resistance in pancreatic cancer: Emerging opportunities by targeting BRCAs and p53	22
The neoantigens derived from transposable elements – A hidden treasure for cancer immunotherapy	22
Reflecting on the cardiac toxicity in non-small cell lung cancer in the era of immune checkpoint inhibitors therapy combined with thoracic radiotherapy	22
Research progress of mitochondria and cytoskeleton crosstalk in tumour development	22
Understanding the role of DNA methylation in colorectal cancer: Mechanisms, detection, and clinical significance	22
Epidermal growth factor receptor PROTACs as an effective strategy for cancer therapy: A review	22
Dual roles of human endogenous retroviruses in cancer progression and antitumor immune response	22
Spatiotemporal heterogeneity and clinical challenge of pancreatic neuroendocrine tumors	22
Machine Learning in Epigenomics: Insights into Cancer Biology and Medicine	22
Epigenetic therapy: Research progress of decitabine in the treatment of solid tumors	21
The interplay between microbiome and host factors in pathogenesis and therapy of head and neck cancer	21
Tumoral heterogeneity in neuroblastoma	21
Centrosome amplification in cancer and cancer-associated human diseases	21
Changing landscape of anti-angiogenic therapy: Novel approaches and clinical perspectives	21
Non-small cell lung cancer: Emerging molecular targeted and immunotherapeutic agents	21
Editorial Board	21
Finding the junction between claudins and endometrial carcinoma	21
CD95 (Fas) and CD95L (FasL)-mediated non-canonical signaling pathways	20
B7-H3 regulates anti-tumor immunity and promotes tumor development in colorectal cancer	20
Tumor microenvironment diversity and plasticity in cancer multidrug resistance	20
βIII-tubulin overexpression in cancer: Causes, consequences, and potential therapies	20
Clinical considerations of CDK4/6 inhibitors in triple-negative breast cancer	20
Role of the intratumoral microbiome in tumor progression and therapeutics implications	20
Psychological intervention to treat distress: An emerging frontier in cancer prevention and therapy	20
The signaling pathways regulated by KRAB zinc-finger proteins in cancer	20
GSDM family and glioma	19
Dietary and serum advanced glycation end-products and clinical outcomes in breast cancer	19
Improving the efficacy of anti-EGFR drugs in GBM: Where we are going?	19
Advances in tuft cells, a chemosensory cell in sequential diseases of the pancreas	19
Molecular and immune pathobiology of human angiosarcoma	19
Cancer-associated fungi: An emerging powerful player in cancer immunotherapy	19
The comparison of pathogenic role and mechanism of Kallistatin and PEDF in tumors	19
Editorial Board	19
Clinical and Molecular Attributes and Evaluation of Pancreatic Cystic Neoplasm	19
Enhancing immune checkpoint blockade therapy of genitourinary malignancies by co-targeting PMN-MDSCs	19
Thymic epithelial tumor medical treatment: A narrative review	19
A review exploring the fusion of oncolytic viruses and cancer immunotherapy: An innovative strategy in the realm of cancer treatment	19
Advances in glioma models using in vivo electroporation to highjack neurodevelopmental processes	19
The role of exosomes in the tumour microenvironment on macrophage polarisation	18
The role of TRIM25 in the occurrence and development of cancers and inflammatory diseases	18

Protein induced by vitamin K absence or antagonist II: Experience to date and future directions	18
The potential of TRP channels as new prognostic and therapeutic targets against prostate cancer progression	18
Odors and cancer: Current status and future directions	18
TERT promoter mutations in gliomas: Molecular roles in tumorigenesis, metastasis, diagnosis, prognosis, therapeutic targeting, and drug resistance	18
Roles of K(H)SRP in modulating gene transcription throughout cancer progression: Insights from cellular studies to clinical perspectives	18
Cyclin-dependent kinases in DNA damage response	18
Interstitial fluid pressure as an emerging biomarker in solid tumors	17
In vitro models: Can they unravel the complexities of cancer cell metastasis?	17
Editorial Board	17
Unveiling Cuproptosis: Mechanistic insights, roles, and leading advances in oncology	17
Biological function, regulatory mechanism, and clinical application of mannose in cancer	17
Implication of Toll-Like Receptors in growth and management of health and diseases: Special focus as a promising druggable target to Prostate Cancer	17
Therapeutic strategies of dual-target small molecules to overcome drug resistance in cancer therapy	17
Epigenetic mechanisms of cancer progression and therapy resistance in estrogen-receptor (ER+) breast cancer	17
Precision medicine and phosphoproteomics for the identification of novel targeted therapeutic avenues in sarcomas	17
Acetyl-CoA regulates lipid metabolism and histone acetylation modification in cancer	16
Perioperative immunotherapy for patients with EGFR mutant non-small cell lung cancer: Unexpected potential benefits	16
Relevance of tumor microbiome in cancer incidence, prognosis, and its clinical implications in therapeutics	16
microRNA-205 in prostate cancer: Overview to clinical translation	16
The progress of immune checkpoint therapy in primary liver cancer	16
Bioelectronic medicines: Therapeutic potential and advancements in next-generation cancer therapy	16
Unravelling the complexity of lncRNAs in autophagy to improve potential cancer therapy	16
Small extracellular vesicles (exosomes) and their cargo in pancreatic cancer: Key roles in the hallmarks of cancer	16
Mechanistic regulation of FOXO transcription factors in the nucleus	16
Combination therapies with Wnt signaling inhibition: A better choice for prostate cancer treatment	16
Advancements in the application of ablative therapy and its combination with immunotherapy in anti-cancer therapy	15
RNF43 and ZNRF3: Versatile regulators at the membrane and their role in cancer	15
Novel therapeutic approaches in GEP-NETs based on genetic and epigenetic alterations	15
Editorial Board	15
Cancer-associated fibroblasts: Mediators of head and neck tumor microenvironment remodeling	15
Editorial Board	15
Advancements in therapeutic peptides: Shaping the future of cancer treatment	15
Achievement in active agent structures as a power tools in tumor angiogenesis imaging	15
E3 ligases and deubiquitinating enzymes regulating the MAPK signaling pathway in cancers	15
Glioma and post-translational modifications: A complex relationship	14
Bacteria-based cancer therapy: Looking forward	14
Roles of miRNAs in regulating ovarian cancer stemness	14
Metabolic tricks of cancer cells	14
The dual role of citrate in cancer	14
Biomechanical properties of laminins and their impact on cancer progression	14
FGFR signaling and endocrine resistance in breast cancer: Challenges for the clinical development of FGFR inhibitors	14
Intercellular adhesion molecule-1 (ICAM-1): From molecular functions to clinical applications in cancer investigation	14
Targeting transposable elements in cancer: developments and opportunities	14
Fingerprint of the oxido-reductase ERO1: A protein disulfide bond producer and supporter of cancer	14
The innate effects of plant secondary metabolites in preclusion of gynecologic cancers: Inflammatory response and therapeutic action	14
Decoding β-catenin associated protein-protein interactions: Emerging cancer therapeutic opportunities	13
Cullin-RING Ligase 4 in Cancer: Structure, Functions, and Mechanisms	13
The role of autophagy in pancreatic cancer progression	13
Recent thymic emigrants as the bridge between thymoma and autoimmune diseases	13
Editorial Board	13
“Intrinsic disorder-protein modification-LLPS-tumor” regulatory axis: From regulatory mechanisms to precision medicine	13
The association between the neuroendocrine system and the tumor immune microenvironment: Emerging directions for cancer immunotherapy	13
Gene regulation by the tumor suppressor p53 – The omics era	13
Ferroptosis and its interaction with tumor immune microenvironment in liver cancer	13
Spartin: At the crossroad between ubiquitination and metabolism in cancer	13
Efficacy and safety of trastuzumab with or without a tyrosine kinase inhibitor for HER2-positive breast cancer: A systematic review and meta-analysis	13
DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer	13
Clinical applications of deep learning in breast MRI	13
Modulation of Ca2+ signaling by antiapoptotic Bcl-2 versus Bcl-xL: From molecular mechanisms to relevance for cancer cell survival	12
Hurdle or thruster: Glucose metabolism of T cells in anti-tumour immunity	12
The role of the NDRG1 in the pathogenesis and treatment of breast cancer	12
Retraction notice to “Coagulation and inflammation in cancer: Limitations and prospects for treatment” [Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877 (2022) 188727]	12
The key role of matrix stiffness in colorectal cancer immunotherapy: mechanisms and therapeutic strategies	12
Targeting the heat shock response induced by modulated electro-hyperthermia (mEHT) in cancer	12
Recent advances in understanding the molecular role of phosphoinositide-specific phospholipase C gamma 1 as an emerging onco-driver and novel therapeutic target in human carcinogenesis	12
Drug resistance in colorectal cancer: An epigenetic overview	12
Advances and challenges in therapeutic resistant biomarkers of neuroblastoma: A comprehensive review	12
Structure, function, signaling pathways and clinical therapeutics: The translational potential of STAT3 as a target for cancer therapy	12
The potential of methioninase for cancer treatment	11
Glioblastoma preclinical models: Strengths and weaknesses	11
New insights into exosome mediated tumor-immune escape: Clinical perspectives and therapeutic strategies	11
Exploration of tumor penetrating peptide iRGD as a potential strategy to enhance tumor penetration of cancer nanotherapeutics	11
Leveraging preclinical models of metastatic breast cancer	11
Epithelial-mesenchymal transition: When tumor cells meet myeloid-derived suppressor cells	11
Metastasis prevention: How to catch metastatic seeds	11
The role of 5-HT metabolism in cancer	11
Advancements in immunotherapy for gastric cancer: Unveiling the potential of immune checkpoint inhibitors and emerging strategies	11
Editorial Board	11
New advances in the therapeutic strategy of head and neck squamous cell carcinoma: A review of latest therapies and cutting-edge research	11
Targeting nanoparticles to malignant tumors	11
Membrane drug transporters in cancer: From chemoresistance mechanism to therapeutic strategies	11
Drivers of cancer metastasis – Arise early and remain present	11
MOMP: A critical event in cell death regulation and anticancer treatment	11
Mechanisms of cancer cachexia and targeted therapeutic strategies	11
The potential roles of p53 signaling reactivation in pancreatic cancer therapy	10
Targeting Bcl-2 for cancer therapy	10
Liquid biopsy in pancreatic cancer – Current perspective and future outlook	10
Activity and resistance to KRASG12C inhibitors in non-small cell lung cancer and colorectal cancer	10
Current and future directions of USP7 interactome in cancer study	10
Find the path of least resistance: Adaptive therapy to delay treatment failure and improve outcomes	10
Unfolded protein response at the cross roads of tumourigenesis, oxygen sensing and drug resistance in clear cell renal cell carcinoma	10
Phase separation in DNA damage response: New insights into cancer development and therapy	10
Tumor-associated neutrophils and neutrophil-targeted cancer therapies	10
Amazing roles of extrachromosomal DNA in cancer progression	10
The emerging role of extracellular vesicles and particles in prostate cancer diagnosis, and risk stratification	10