Biochimica et Biophysica Acta-Reviews on Cancer

Article	Citations
Tumour cell-induced platelet aggregation in breast cancer: Scope of metal nanoparticles	277
TSPAN1, a novel tetraspanin member highly involved in carcinogenesis and chemoresistance	229
Spatiotemporal dynamics of the pre-metastatic niche: remodeling of lung microenvironment before breast cancer metastasis and targeted intervention strategies	215
Uveal melanoma modeling in mice and zebrafish	183
Reflections on drug resistance to KRAS inhibitors and gene silencing/editing tools for targeting mutant KRAS in cancer treatment	160
VISTA as a context-dependent immune checkpoint: Implications for tumor immunity and autoimmune pathogenesis	115
Progress and challenges of immunotherapy in triple-negative breast cancer	105
Modeling bladder cancer in the laboratory: Insights from patient-derived organoids	99
ESR1 activating mutations: From structure to clinical application	93
Is tumour-expressed aminopeptidase N (APN/CD13) structurally and functionally unique?	93
Unlocking the power of innate lymphoid cell plasticity in the tumor microenvironment: A revolutionary pathway for cancer immunotherapy	89
Nutrition and dietary restrictions in cancer prevention	85
miRNAs and androgen deprivation therapy for prostate cancer	84
Advances in epigenetic modifications and cervical cancer research	79
Microbial influence on triggering and treatment of host cancer: An intestinal barrier perspective	77
Decoding the role of FOXP3 in esophageal cancer: Underlying mechanisms and therapeutic implications	73
Epigenetic changes associated with Bacillus Calmette-Guerin (BCG) treatment in bladder cancer	66
Insights into the role of connexins and specialized intercellular communication pathways in breast cancer: Mechanisms and applications	65
In what area of biology has a “new” type of cell death been discovered?	65
Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature	62
Biomarkers in high grade serous ovarian cancer	60
Contribution of CXCR3-mediated signaling in the metastatic cascade of solid malignancies	54
Targeting lipid metabolism in cancer metastasis	54
The VEGF/VEGFR2 system in ovarian cancer: From functional to pharmacological significance	52
Fascin-1 in primary liver cancers, perspectives for targeted therapy	51

Exploring synthetic lethality in cancer therapy: CRISPR-Cas9 technology offers new hope	50
Mitochondrial metabolism in laryngeal cancer: therapeutic mechanisms and prospects	49
Dual perspective on autophagy in glioma: Detangling the dichotomous mechanisms of signaling pathways for therapeutic insights	49
CCL20-CCR6 signaling in tumor microenvironment: Functional roles, mechanisms, and immunotherapy targeting	48
Extracellular vesicles in cancer therapy: Roles, potential application, and challenges	47
Transcription factors in glioblastoma – Molecular pathogenesis and clinical implications	47
Long non-coding RNAs: Fundamental regulators and emerging targets of cancer stem cells	46
S100A8 and S100A9 in Cancer	46
Advances and prospects of mRNA vaccines in cancer immunotherapy	46
Recent insights into RNA m5C methylation modification in hepatocellular carcinoma	46
Small non-coding RNAs and pancreatic ductal adenocarcinoma: Linking diagnosis, pathogenesis, drug resistance, and therapeutic potential	45
Multifaceted roles of neutrophils in tumor microenvironment	45
Multiple therapeutic approaches of glioblastoma multiforme: From terminal to therapy	45
Interleukin-21 as an adjuvant in cancer immunotherapy: Current advances and future directions	45
Multiple impacts of Naa10p on cancer progression: Molecular functions and clinical prospects	44
Prognostic features of the tumour microenvironment in oesophageal adenocarcinoma	44
Enhancing the anti-tumor response by combining DNA damage repair inhibitors in the treatment of solid tumors	44
The interplay of obesity, microbiome dynamics, and innovative anti-obesity strategies in the context of endometrial cancer progression and therapeutic approaches	43
Targeting Cdc20 for cancer therapy	43
Editorial Board	43
Current advances in comprehensive omics data mining for oncology and cancer research	42
Vagus innervation in the gastrointestinal tumor: Current understanding and challenges	42
An overview of BAP1 biological functions and current therapeutics	41
Predictive and prognostic value of PIK3CA mutations in HER2-positive breast cancer treated with tyrosine kinase inhibitors: A systematic review and meta-analysis	41
Combination therapy in cancer: The potential of tetrandrine as a polytherapy for acute myeloid leukemia	40
Modulation of N-glycosylation in the PD-1: PD-L1 axis as a strategy to enhance cancer immunotherapies	40
The NLRP3 inflammasome and its role in acute myeloid leukemia onset and development	40
Focus on mast cells in the tumor microenvironment: Current knowledge and future directions	39
Muscle-to-tumor crosstalk: The effect of exercise-induced myokine on cancer progression	39
Ubiquitination/de-ubiquitination: A promising therapeutic target for PTEN reactivation in cancer	39
Epithelial-Mesenchymal Transition in Cancer: A Focus on Itraconazole, a Hedgehog Inhibitor	39
The Pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: Old spectacles with new insights	39
Antibody-drug conjugates in HER-2 negative breast cancers with poor prognosis	39
Platinum-based systematic therapy in triple-negative breast cancer	37
CD8+ T-cell exhaustion: Impediment to triple-negative breast cancer (TNBC) immunotherapy	37
Unveiling the potential of gene editing techniques in revolutionizing Cancer treatment: A comprehensive overview	36
Interactions between cancer cells and tumor-associated macrophages in tumor microenvironment	35
Matrisomics: Beyond the extracellular matrix for unveiling tumor microenvironment	35
Cellular functions, molecular signalings and therapeutic applications: Translational potential of deubiquitylating enzyme USP9X as a drug target in cancer treatment	34
Antibody-drug conjugates in breast cancer: Marching from HER2-overexpression into HER2-low	34
Implications of viral infection in cancer development	33
Abnormal metabolism in hepatic stellate cells: Pandora's box of MAFLD related hepatocellular carcinoma	33
Advances in clinical immunotherapy for gastric cancer	32
ASPORIN: A root of the matter in tumors and their host environment	32
In vitro anticancer properties of anthocyanins: A systematic review	31
A role for RIO kinases in the crosshair of cancer research and therapy	31
Nondiploid cancer cells: Stress, tolerance and therapeutic inspirations	31
Intestinal multicellular organoids to study colorectal cancer	31
HOXA1, a breast cancer oncogene	30
Directing CAR T cells towards the tumor vasculature for the treatment of solid tumors	30

Overview of splicing variation in ovarian cancer	30
Research progress on the regulatory role of lactate and lactylation in tumor microenvironment	30
Refinement of safety and efficacy of anti-cancer chemotherapeutics by tailoring their site-specific intracellular bioavailability through transporter modulation	30
New target DDR1: A “double-edged sword” in solid tumors	29
Emerging strategies to overcome PARP inhibitors' resistance in ovarian cancer	29
Colorectal cancer: Metabolic interactions reshape the tumor microenvironment	29
USP7 - a crucial regulator of cancer hallmarks	29
A holistic view on c-Kit in cancer: Structure, signaling, pathophysiology and its inhibitors	29
Carbonic anhydrase IX: An atypical target for innovative therapies in cancer	29
The microbiota-m6A-metabolism axis: Implications for therapeutic strategies in gastrointestinal cancers	29
Strategies for studying immune and non-immune human and canine mammary gland cancer tumour infiltrate	28
Exosomal non-coding RNAs (ncRNAs) as potential biomarkers in tumor early diagnosis	28
Schwann cells and enteric glial cells: Emerging stars in colorectal cancer	28
Unveiling the TGF-β/Smad signaling in renal carcinoma progression: Prognostic and therapeutic insights	28
RUNX1 and cancer	28
Dual role of Snail1 as transcriptional repressor and activator	28
Unraveling molecular aberrations and pioneering therapeutic strategies in osteosarcoma	28
A novel approach to reducing disparities in health outcomes by enhancing interpretation of cancer clinical trials for underrepresented patient groups	27
Stress granules dynamics and promising functions in pancreatic cancer	27
Exploring the gut microbiome: A potential biomarker for cancer diagnosis, prognosis, and therapy	27
Interleukin-1 signaling in solid organ malignancies	27
Role of F-box proteins in human upper gastrointestinal tumors	26
Epigenetic regulation of cancer-associated fibroblast heterogeneity	26
From resistance to resilience: Uncovering chemotherapeutic resistance mechanisms; insights from established models	26
Perspectives and mechanisms for targeting mitotic catastrophe in cancer treatment	25
Keep your eyes peeled for long noncoding RNAs: Explaining their boundless role in cancer metastasis, drug resistance, and clinical application	25
To kill a cancer: Targeting the immune inhibitory checkpoint molecule, B7-H3	25
Sequencing of antibody drug conjugates in breast cancer: Evidence gap and future directions	25
New insight into the role of SMAD4 mutation/deficiency in the prognosis and therapeutic resistance of pancreatic ductal adenocarcinomas	25
Keratin 1 as a cell-surface receptor in cancer	25
Potentially diagnostic and prognostic roles of piRNAs/PIWIs in pancreatic cancer: A review	25
Scientific and clinical relevance of non-cellular tumor microenvironment components in ovarian cancer chemotherapy resistance	24
Artificial intelligence and allied subsets in early detection and preclusion of gynecological cancers	24
Proteomics of post-translational modifications in colorectal cancer: Discovery of new biomarkers	24
A special subtype: Revealing the potential intervention and great value of KRAS wildtype pancreatic cancer	24
Augmentation of the EPR effect by mild hyperthermia to improve nanoparticle delivery to the tumor	24
SNARE proteins: Core engines of membrane fusion in cancer	24
Understanding the role of DNA methylation in colorectal cancer: Mechanisms, detection, and clinical significance	23
The correlation between gut and intra-tumor microbiota and PDAC: Etiology, diagnostics and therapeutics	23
Research progress of mitochondria and cytoskeleton crosstalk in tumour development	23
Non-small cell lung cancer: Emerging molecular targeted and immunotherapeutic agents	23
Reflecting on the cardiac toxicity in non-small cell lung cancer in the era of immune checkpoint inhibitors therapy combined with thoracic radiotherapy	23
Spatiotemporal heterogeneity and clinical challenge of pancreatic neuroendocrine tumors	23
The neoantigens derived from transposable elements – A hidden treasure for cancer immunotherapy	23
Role of Yin Yang 1 (YY1) on microenvironment, signaling pathways, and epigenetics in lung cancer	23
Radiotherapy modulates autophagy to reshape the tumor immune microenvironment to enhance anti-tumor immunity in esophageal cancer	23
Emerging roles of PIWI-interacting RNAs (piRNAs) and PIWI proteins in head and neck cancer and their potential clinical implications	23
Expression and function of NF-Y subunits in cancer	23
Dual roles of human endogenous retroviruses in cancer progression and antitumor immune response	23
Overcoming therapeutic resistance in pancreatic cancer: Emerging opportunities by targeting BRCAs and p53	22
Tumoral heterogeneity in neuroblastoma	22
B7-H3 regulates anti-tumor immunity and promotes tumor development in colorectal cancer	22
Role of the intratumoral microbiome in tumor progression and therapeutics implications	22
Machine Learning in Epigenomics: Insights into Cancer Biology and Medicine	22
Histone deacetylase complexes: Structure, regulation and function	22
Finding the junction between claudins and endometrial carcinoma	22
Changing landscape of anti-angiogenic therapy: Novel approaches and clinical perspectives	22
Epidermal growth factor receptor PROTACs as an effective strategy for cancer therapy: A review	22
Editorial Board	22
Psychological intervention to treat distress: An emerging frontier in cancer prevention and therapy	22
Epigenetic therapy: Research progress of decitabine in the treatment of solid tumors	21
Unraveling metastatic timing: insights and challenges from genomic evolution	21
Tumor microenvironment diversity and plasticity in cancer multidrug resistance	21
Clinical considerations of CDK4/6 inhibitors in triple-negative breast cancer	21
The signaling pathways regulated by KRAB zinc-finger proteins in cancer	21
CD95 (Fas) and CD95L (FasL)-mediated non-canonical signaling pathways	21
Editorial Board	20
Advances in glioma models using in vivo electroporation to highjack neurodevelopmental processes	20
Advances in tuft cells, a chemosensory cell in sequential diseases of the pancreas	20
Roles of K(H)SRP in modulating gene transcription throughout cancer progression: Insights from cellular studies to clinical perspectives	20
The interplay between microbiome and host factors in pathogenesis and therapy of head and neck cancer	20
βIII-tubulin overexpression in cancer: Causes, consequences, and potential therapies	20
Enhancing immune checkpoint blockade therapy of genitourinary malignancies by co-targeting PMN-MDSCs	20
A review exploring the fusion of oncolytic viruses and cancer immunotherapy: An innovative strategy in the realm of cancer treatment	19
Decoding the role of intratumoral microbiota in gastric cancer	19
TERT promoter mutations in gliomas: Molecular roles in tumorigenesis, metastasis, diagnosis, prognosis, therapeutic targeting, and drug resistance	19
Cancer-associated fungi: An emerging powerful player in cancer immunotherapy	19
Osteoblasts in bone metastasis: Key players in the tumor microenvironment and therapeutic targets	19
EV-mediated asymmetrical crosstalk between CAFs and cancer cells in the tumor microenvironment	19
Improving the efficacy of anti-EGFR drugs in GBM: Where we are going?	19

The comparison of pathogenic role and mechanism of Kallistatin and PEDF in tumors	19
Epigenetic mechanisms of cancer progression and therapy resistance in estrogen-receptor (ER+) breast cancer	19
Molecular and immune pathobiology of human angiosarcoma	19
Comprehensive insights of etiological drivers of hepatocellular carcinoma: Fostering targeted nano delivery to anti-cancer regimes	19
GSDM family and glioma	18
The role of exosomes in the tumour microenvironment on macrophage polarisation	18
The potential of TRP channels as new prognostic and therapeutic targets against prostate cancer progression	18
Unveiling Cuproptosis: Mechanistic insights, roles, and leading advances in oncology	18
Clinical and Molecular Attributes and Evaluation of Pancreatic Cystic Neoplasm	18
Therapeutic strategies of dual-target small molecules to overcome drug resistance in cancer therapy	18
Thymic epithelial tumor medical treatment: A narrative review	18
The role of TRIM25 in the occurrence and development of cancers and inflammatory diseases	18
Biological function, regulatory mechanism, and clinical application of mannose in cancer	18
Dietary and serum advanced glycation end-products and clinical outcomes in breast cancer	17
Odors and cancer: Current status and future directions	17
Editorial Board	17
Interstitial fluid pressure as an emerging biomarker in solid tumors	17
Protein induced by vitamin K absence or antagonist II: Experience to date and future directions	17
Novel therapeutic approaches in GEP-NETs based on genetic and epigenetic alterations	17
Mechanistic regulation of FOXO transcription factors in the nucleus	17
Cyclin-dependent kinases in DNA damage response	17
Relevance of tumor microbiome in cancer incidence, prognosis, and its clinical implications in therapeutics	17
In vitro models: Can they unravel the complexities of cancer cell metastasis?	16
Key subunits of γ-secretase complex and breast cancer progression: biological function, regulation mode and therapeutic potential	16
Cancer-associated fibroblasts: Mediators of head and neck tumor microenvironment remodeling	16
E3 ligases and deubiquitinating enzymes regulating the MAPK signaling pathway in cancers	16
Unravelling the complexity of lncRNAs in autophagy to improve potential cancer therapy	16
Corrigendum to “Unveiling the TGF-β/Smad signaling in renal carcinoma progression: Prognostic and therapeutic insights” [Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, Volume 1880, Issue 4,	16
The progress of immune checkpoint therapy in primary liver cancer	16
Perioperative immunotherapy for patients with EGFR mutant non-small cell lung cancer: Unexpected potential benefits	16
Precision medicine and phosphoproteomics for the identification of novel targeted therapeutic avenues in sarcomas	16
microRNA-205 in prostate cancer: Overview to clinical translation	16
RNF43 and ZNRF3: Versatile regulators at the membrane and their role in cancer	16
Implication of Toll-Like Receptors in growth and management of health and diseases: Special focus as a promising druggable target to Prostate Cancer	16
Small extracellular vesicles (exosomes) and their cargo in pancreatic cancer: Key roles in the hallmarks of cancer	16
Bioelectronic medicines: Therapeutic potential and advancements in next-generation cancer therapy	15
FGFR signaling and endocrine resistance in breast cancer: Challenges for the clinical development of FGFR inhibitors	15
Acetyl-CoA regulates lipid metabolism and histone acetylation modification in cancer	15
Editorial Board	15
Advancements in therapeutic peptides: Shaping the future of cancer treatment	15
Targeting transposable elements in cancer: developments and opportunities	15
Combination therapies with Wnt signaling inhibition: A better choice for prostate cancer treatment	15
Bacteria-based cancer therapy: Looking forward	15
The dual role of citrate in cancer	15
Editorial Board	15
Fingerprint of the oxido-reductase ERO1: A protein disulfide bond producer and supporter of cancer	14
Glioma and post-translational modifications: A complex relationship	14
Recent thymic emigrants as the bridge between thymoma and autoimmune diseases	14
Editorial Board	14
Getting the GIST of long non-coding RNA	14
Roles of miRNAs in regulating ovarian cancer stemness	14
The innate effects of plant secondary metabolites in preclusion of gynecologic cancers: Inflammatory response and therapeutic action	14
Metabolic tricks of cancer cells	14
Intercellular adhesion molecule-1 (ICAM-1): From molecular functions to clinical applications in cancer investigation	14
Biomechanical properties of laminins and their impact on cancer progression	14
Advancements in the application of ablative therapy and its combination with immunotherapy in anti-cancer therapy	14
The association between the neuroendocrine system and the tumor immune microenvironment: Emerging directions for cancer immunotherapy	14
Exosomes: Traversing the blood-brain barrier and their therapeutic potential in brain cancer	13
DNA methylation-based diagnostic, prognostic, and predictive biomarkers in colorectal cancer	13
Modulation of Ca2+ signaling by antiapoptotic Bcl-2 versus Bcl-xL: From molecular mechanisms to relevance for cancer cell survival	13
Shared mechanisms for metastasis and drug resistance in prostate cancer	13
Efficacy and safety of trastuzumab with or without a tyrosine kinase inhibitor for HER2-positive breast cancer: A systematic review and meta-analysis	13
The key role of matrix stiffness in colorectal cancer immunotherapy: mechanisms and therapeutic strategies	13
The role of autophagy in pancreatic cancer progression	13
Decoding β-catenin associated protein-protein interactions: Emerging cancer therapeutic opportunities	13
Charting the landscape of intratumoral microbiota in lung cancer: From bench to bedside	13
Drug resistance in colorectal cancer: An epigenetic overview	13
“Intrinsic disorder-protein modification-LLPS-tumor” regulatory axis: From regulatory mechanisms to precision medicine	13
Gene regulation by the tumor suppressor p53 – The omics era	13
Spartin: At the crossroad between ubiquitination and metabolism in cancer	13
Structure, function, signaling pathways and clinical therapeutics: The translational potential of STAT3 as a target for cancer therapy	12
Ferroptosis and its interaction with tumor immune microenvironment in liver cancer	12
Advances and challenges in therapeutic resistant biomarkers of neuroblastoma: A comprehensive review	12
miRNA expression based modulation: A new paradigm for the treatment of chronic myeloid leukemia	12
Membrane drug transporters in cancer: From chemoresistance mechanism to therapeutic strategies	12
Advancements in immunotherapy for gastric cancer: Unveiling the potential of immune checkpoint inhibitors and emerging strategies	12
The enzyme glycogen synthase kinase-3 is associated with specific forms of oncogenesis; what more do we need to know to achieve clinical benefit?	12
Clinical applications of deep learning in breast MRI	12
BTB domain and CNC homolog 2: A master regulator that controls immune response and cancer progression	12
Metastasis prevention: How to catch metastatic seeds	12
Retraction notice to “Coagulation and inflammation in cancer: Limitations and prospects for treatment” [Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877 (2022) 188727]	12
Biological mechanisms and immunotherapy of brain metastases in non-small cell lung cancer	12
Recent advances in understanding the molecular role of phosphoinositide-specific phospholipase C gamma 1 as an emerging onco-driver and novel therapeutic target in human carcinogenesis	12
Cullin-RING Ligase 4 in Cancer: Structure, Functions, and Mechanisms	12
Targeting the heat shock response induced by modulated electro-hyperthermia (mEHT) in cancer	12
Drivers of cancer metastasis – Arise early and remain present	12
New insights into exosome mediated tumor-immune escape: Clinical perspectives and therapeutic strategies	12
MOMP: A critical event in cell death regulation and anticancer treatment	12
The potential roles of p53 signaling reactivation in pancreatic cancer therapy	11
Find the path of least resistance: Adaptive therapy to delay treatment failure and improve outcomes	11
Functional impact of non-coding RNAs in high-grade breast carcinoma: Moving from resistance to clinical applications: A comprehensive review	11
Corrigendum to “Recent thymic emigrants as the bridge between thymoma and autoimmune diseases” [Biochim Biophys Acta Rev Cancer. 2022;1877(3):188730.]	11
Leveraging preclinical models of metastatic breast cancer	11
Editorial Board	11
Activity and resistance to KRASG12C inhibitors in non-small cell lung cancer and colorectal cancer	11