Biochimica et Biophysica Acta-Reviews on Cancer

Article	Citations
The bridging role of neutrophils in the progression of inflammation-induced colorectal cancer	285
Modeling bladder cancer in the laboratory: Insights from patient-derived organoids	262
Microbial influence on triggering and treatment of host cancer: An intestinal barrier perspective	220
Progress and challenges of immunotherapy in triple-negative breast cancer	197
Advances in epigenetic modifications and cervical cancer research	172
Targeted drug delivery systems in Lymphoma treatment: Advances and clinical perspectives	121
The role of protein glycosylation in colorectal cancer: From molecular pathways to clinical applications	116
Unlocking the power of innate lymphoid cell plasticity in the tumor microenvironment: A revolutionary pathway for cancer immunotherapy	108
VISTA as a context-dependent immune checkpoint: Implications for tumor immunity and autoimmune pathogenesis	103
Is tumour-expressed aminopeptidase N (APN/CD13) structurally and functionally unique?	102
Uveal melanoma modeling in mice and zebrafish	100
Nutrition and dietary restrictions in cancer prevention	99
TSPAN1, a novel tetraspanin member highly involved in carcinogenesis and chemoresistance	90
Reflections on drug resistance to KRAS inhibitors and gene silencing/editing tools for targeting mutant KRAS in cancer treatment	89
ESR1 activating mutations: From structure to clinical application	80
Tumour cell-induced platelet aggregation in breast cancer: Scope of metal nanoparticles	78
miRNAs and androgen deprivation therapy for prostate cancer	74
Spatiotemporal dynamics of the pre-metastatic niche: remodeling of lung microenvironment before breast cancer metastasis and targeted intervention strategies	71
Mitochondrial metabolism in laryngeal cancer: therapeutic mechanisms and prospects	68
Dual perspective on autophagy in glioma: Detangling the dichotomous mechanisms of signaling pathways for therapeutic insights	67
Yin yang 1: a potential regulator of immune related diseases and cancer immunity	65
Unveiling anaphylatoxins: Pioneering cancer therapies through complement system insights	65
Biomarkers in high grade serous ovarian cancer	63
Insights into the role of connexins and specialized intercellular communication pathways in breast cancer: Mechanisms and applications	59
Extracellular vesicles in cancer therapy: Roles, potential application, and challenges	58

Detection methods for mitochondrial DNA heteroplasmy and their potential single-cell applications in cancer	56
Long non-coding RNAs: Fundamental regulators and emerging targets of cancer stem cells	56
In what area of biology has a “new” type of cell death been discovered?	54
Targeting lipid metabolism in cancer metastasis	54
Transcription factors in glioblastoma – Molecular pathogenesis and clinical implications	53
CCL20-CCR6 signaling in tumor microenvironment: Functional roles, mechanisms, and immunotherapy targeting	53
Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature	52
Contribution of CXCR3-mediated signaling in the metastatic cascade of solid malignancies	51
Epigenetic changes associated with Bacillus Calmette-Guerin (BCG) treatment in bladder cancer	51
Decoding the role of FOXP3 in esophageal cancer: Underlying mechanisms and therapeutic implications	50
The VEGF/VEGFR2 system in ovarian cancer: From functional to pharmacological significance	49
Revisiting CHK1 and WEE1 kinases as therapeutic targets in cancer	49
Fascin-1 in primary liver cancers, perspectives for targeted therapy	48
Exploring synthetic lethality in cancer therapy: CRISPR-Cas9 technology offers new hope	48
Small non-coding RNAs and pancreatic ductal adenocarcinoma: Linking diagnosis, pathogenesis, drug resistance, and therapeutic potential	48
S100A8 and S100A9 in Cancer	48
Advances and prospects of mRNA vaccines in cancer immunotherapy	48
Multiple impacts of Naa10p on cancer progression: Molecular functions and clinical prospects	47
Integrating multi-omics proteomic approaches in deciphering the tumor microenvironment and therapeutic resistance mechanisms in prostate cancer	47
Inhibition of nucleotide excision repair proteins associated with cancer chemotherapy	47
Interleukin-21 as an adjuvant in cancer immunotherapy: Current advances and future directions	45
STIM1-mediated calcium signalling in cancer: Its relation to tumour aggressiveness and therapeutic horizons	45
Multifaceted roles of neutrophils in tumor microenvironment	45
Prognostic features of the tumour microenvironment in oesophageal adenocarcinoma	45
Recent insights into RNA m5C methylation modification in hepatocellular carcinoma	44
Enhancing the anti-tumor response by combining DNA damage repair inhibitors in the treatment of solid tumors	44
The interplay of obesity, microbiome dynamics, and innovative anti-obesity strategies in the context of endometrial cancer progression and therapeutic approaches	43
Mitochondrial dynamics and metabolic attributes regulate function of natural killer cell and infiltration in tumor microenvironment modulating disease progression	43
Targeting Cdc20 for cancer therapy	42
Multiple therapeutic approaches of glioblastoma multiforme: From terminal to therapy	42
Olfactomedin 4 in cancer development and progression	41
Targeting the triad: phenotypic plasticity, tumor microenvironment and bone microenvironment in prostate cancer bone-metastatic events	41
Matrisomics: Beyond the extracellular matrix for unveiling tumor microenvironment	40
A role for RIO kinases in the crosshair of cancer research and therapy	40
Cellular functions, molecular signalings and therapeutic applications: Translational potential of deubiquitylating enzyme USP9X as a drug target in cancer treatment	39
Unveiling the potential of gene editing techniques in revolutionizing Cancer treatment: A comprehensive overview	39
Targetable axes of tumor-associated macrophages: An MSF framework for precision immunotherapy	39
Platinum-based systematic therapy in triple-negative breast cancer	39
Current advances in comprehensive omics data mining for oncology and cancer research	38
Interactions between cancer cells and tumor-associated macrophages in tumor microenvironment	38
Editorial Board	38
Implications of viral infection in cancer development	37
Vagus innervation in the gastrointestinal tumor: Current understanding and challenges	37
ASPORIN: A root of the matter in tumors and their host environment	36
Nondiploid cancer cells: Stress, tolerance and therapeutic inspirations	36
Abnormal metabolism in hepatic stellate cells: Pandora's box of MAFLD related hepatocellular carcinoma	36
CD8+ T-cell exhaustion: Impediment to triple-negative breast cancer (TNBC) immunotherapy	36
Antibody-drug conjugates in breast cancer: Marching from HER2-overexpression into HER2-low	35
Epithelial-Mesenchymal Transition in Cancer: A Focus on Itraconazole, a Hedgehog Inhibitor	33
An overview of BAP1 biological functions and current therapeutics	33

Ubiquitination/de-ubiquitination: A promising therapeutic target for PTEN reactivation in cancer	33
Intestinal multicellular organoids to study colorectal cancer	33
The Pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: Old spectacles with new insights	32
Modulation of N-glycosylation in the PD-1: PD-L1 axis as a strategy to enhance cancer immunotherapies	32
Focus on mast cells in the tumor microenvironment: Current knowledge and future directions	32
In vitro anticancer properties of anthocyanins: A systematic review	32
Combination therapy in cancer: The potential of tetrandrine as a polytherapy for acute myeloid leukemia	31
Refinement of safety and efficacy of anti-cancer chemotherapeutics by tailoring their site-specific intracellular bioavailability through transporter modulation	31
Antibody-drug conjugates in HER-2 negative breast cancers with poor prognosis	31
The NLRP3 inflammasome and its role in acute myeloid leukemia onset and development	31
Advances in clinical immunotherapy for gastric cancer	31
Muscle-to-tumor crosstalk: The effect of exercise-induced myokine on cancer progression	30
Exosomal non-coding RNAs (ncRNAs) as potential biomarkers in tumor early diagnosis	30
Research progress on the regulatory role of lactate and lactylation in tumor microenvironment	30
Predictive and prognostic value of PIK3CA mutations in HER2-positive breast cancer treated with tyrosine kinase inhibitors: A systematic review and meta-analysis	30
Emerging strategies to overcome PARP inhibitors' resistance in ovarian cancer	30
The microbiota-m6A-metabolism axis: Implications for therapeutic strategies in gastrointestinal cancers	30
M6A methylation in tumor immune microenvironment: Multidimensional mechanism and targeted therapy strategies	29
USP7 - a crucial regulator of cancer hallmarks	29
A holistic view on c-Kit in cancer: Structure, signaling, pathophysiology and its inhibitors	29
Unveiling the TGF-β/Smad signaling in renal carcinoma progression: Prognostic and therapeutic insights	29
Unraveling molecular aberrations and pioneering therapeutic strategies in osteosarcoma	28
Overview of splicing variation in ovarian cancer	28
Immune archetypes TIME classification system for nasopharyngeal carcinoma: A new direction for precision immunotherapy	28
Taurine and cancer: Biological properties and multifaceted roles in cancer progression	28
Strategies for studying immune and non-immune human and canine mammary gland cancer tumour infiltrate	27
Exploring the gut microbiome: A potential biomarker for cancer diagnosis, prognosis, and therapy	27
HOXA1, a breast cancer oncogene	27
Schwann cells and enteric glial cells: Emerging stars in colorectal cancer	27
Dual role of Snail1 as transcriptional repressor and activator	27
SNARE proteins: Core engines of membrane fusion in cancer	26
New target DDR1: A “double-edged sword” in solid tumors	26
Artificial intelligence and allied subsets in early detection and preclusion of gynecological cancers	26
RUNX1 and cancer	26
Colorectal cancer: Metabolic interactions reshape the tumor microenvironment	26
Potentially diagnostic and prognostic roles of piRNAs/PIWIs in pancreatic cancer: A review	26
Carbonic anhydrase IX: An atypical target for innovative therapies in cancer	26
Directing CAR T cells towards the tumor vasculature for the treatment of solid tumors	26
Epigenetic regulation of cancer-associated fibroblast heterogeneity	25
New insight into the role of SMAD4 mutation/deficiency in the prognosis and therapeutic resistance of pancreatic ductal adenocarcinomas	25
Perspectives and mechanisms for targeting mitotic catastrophe in cancer treatment	25
From resistance to resilience: Uncovering chemotherapeutic resistance mechanisms; insights from established models	25
Stress granules dynamics and promising functions in pancreatic cancer	25
Metabolic insights into TAMs and the tumor immune microenvironment: Regulatory mechanisms and therapeutic interventions	25
Keratin 1 as a cell-surface receptor in cancer	25
Scientific and clinical relevance of non-cellular tumor microenvironment components in ovarian cancer chemotherapy resistance	25
Role of macrophage PKM2 in inflammation and tumor progression and its targeted therapy	25
Interleukin-1 signaling in solid organ malignancies	25
Dietary sugar intervention: A promising approach for cancer therapy	25
A novel approach to reducing disparities in health outcomes by enhancing interpretation of cancer clinical trials for underrepresented patient groups	25
Role of F-box proteins in human upper gastrointestinal tumors	25
Keep your eyes peeled for long noncoding RNAs: Explaining their boundless role in cancer metastasis, drug resistance, and clinical application	25
Understanding the role of DNA methylation in colorectal cancer: Mechanisms, detection, and clinical significance	24
Sequencing of antibody drug conjugates in breast cancer: Evidence gap and future directions	24
Proteomics of post-translational modifications in colorectal cancer: Discovery of new biomarkers	24
Research progress of mitochondria and cytoskeleton crosstalk in tumour development	24
Reflecting on the cardiac toxicity in non-small cell lung cancer in the era of immune checkpoint inhibitors therapy combined with thoracic radiotherapy	24
To kill a cancer: Targeting the immune inhibitory checkpoint molecule, B7-H3	24
Radiotherapy modulates autophagy to reshape the tumor immune microenvironment to enhance anti-tumor immunity in esophageal cancer	24
Advances in the combination of immunoadjuvants and tumor ablation: Mediating immune effects to enhance anti-tumor efficacy	24
Augmentation of the EPR effect by mild hyperthermia to improve nanoparticle delivery to the tumor	24
Role of Yin Yang 1 (YY1) on microenvironment, signaling pathways, and epigenetics in lung cancer	24
Machine Learning in Epigenomics: Insights into Cancer Biology and Medicine	23
Expression and function of NF-Y subunits in cancer	23
A special subtype: Revealing the potential intervention and great value of KRAS wildtype pancreatic cancer	23
Non-small cell lung cancer: Emerging molecular targeted and immunotherapeutic agents	23
Corrigendum to “Snail1 as a key prognostic biomarker of cancer-associated fibroblasts in breast tumors” [Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, volume 1880 (2025) / 189316]	23
Emerging roles of PIWI-interacting RNAs (piRNAs) and PIWI proteins in head and neck cancer and their potential clinical implications	22
The correlation between gut and intra-tumor microbiota and PDAC: Etiology, diagnostics and therapeutics	22
Spatiotemporal heterogeneity and clinical challenge of pancreatic neuroendocrine tumors	22
Dual roles of human endogenous retroviruses in cancer progression and antitumor immune response	22
Overcoming therapeutic resistance in pancreatic cancer: Emerging opportunities by targeting BRCAs and p53	22
The neoantigens derived from transposable elements – A hidden treasure for cancer immunotherapy	21
Tumor microenvironment diversity and plasticity in cancer multidrug resistance	21
Psychological intervention to treat distress: An emerging frontier in cancer prevention and therapy	21
Tumoral heterogeneity in neuroblastoma	21
The signaling pathways regulated by KRAB zinc-finger proteins in cancer	21
βIII-tubulin overexpression in cancer: Causes, consequences, and potential therapies	21
Histone deacetylase complexes: Structure, regulation and function	21
Epidermal growth factor receptor PROTACs as an effective strategy for cancer therapy: A review	21

Role of the intratumoral microbiome in tumor progression and therapeutics implications	21
CD95 (Fas) and CD95L (FasL)-mediated non-canonical signaling pathways	20
The interplay between microbiome and host factors in pathogenesis and therapy of head and neck cancer	20
Anoikis and NETosis in colorectal cancer liver metastasis: the relationship and perspectives	20
Editorial Board	20
Epigenetic therapy: Research progress of decitabine in the treatment of solid tumors	20
Nanoparticulate delivery and targeting of RNA to the brain	20
Changing landscape of anti-angiogenic therapy: Novel approaches and clinical perspectives	20
Finding the junction between claudins and endometrial carcinoma	20
Cancer stem cells in focus: Deciphering the dynamic functional landscape of stemness in cancer	20
Comprehensive insights of etiological drivers of hepatocellular carcinoma: Fostering targeted nano delivery to anti-cancer regimes	19
Metabolic reprogramming in breast cancer: Pathways driving progression, drug resistance, and emerging therapeutics	19
Osteoblasts in bone metastasis: Key players in the tumor microenvironment and therapeutic targets	19
Clinical considerations of CDK4/6 inhibitors in triple-negative breast cancer	19
Roles of K(H)SRP in modulating gene transcription throughout cancer progression: Insights from cellular studies to clinical perspectives	19
The potential of TRP channels as new prognostic and therapeutic targets against prostate cancer progression	19
Unraveling metastatic timing: insights and challenges from genomic evolution	19
B7-H3 regulates anti-tumor immunity and promotes tumor development in colorectal cancer	19
Unveiling Cuproptosis: Mechanistic insights, roles, and leading advances in oncology	19
Cyclin-dependent kinases in DNA damage response	18
Protein induced by vitamin K absence or antagonist II: Experience to date and future directions	18
Advances in tuft cells, a chemosensory cell in sequential diseases of the pancreas	18
TERT promoter mutations in gliomas: Molecular roles in tumorigenesis, metastasis, diagnosis, prognosis, therapeutic targeting, and drug resistance	18
EV-mediated asymmetrical crosstalk between CAFs and cancer cells in the tumor microenvironment	18
Dietary and serum advanced glycation end-products and clinical outcomes in breast cancer	18
Advances in glioma models using in vivo electroporation to highjack neurodevelopmental processes	18
Editorial Board	18
Epigenetic mechanisms of cancer progression and therapy resistance in estrogen-receptor (ER+) breast cancer	18
Molecular and immune pathobiology of human angiosarcoma	18
Clinical and Molecular Attributes and Evaluation of Pancreatic Cystic Neoplasm	18
Biological function, regulatory mechanism, and clinical application of mannose in cancer	18
Decoding the role of intratumoral microbiota in gastric cancer	17
GSDM family and glioma	17
The role of exosomes in the tumour microenvironment on macrophage polarisation	17
Thymic epithelial tumor medical treatment: A narrative review	17
The comparison of pathogenic role and mechanism of Kallistatin and PEDF in tumors	17
Cancer-associated fungi: An emerging powerful player in cancer immunotherapy	17
Improving the efficacy of anti-EGFR drugs in GBM: Where we are going?	17
Enhancing immune checkpoint blockade therapy of genitourinary malignancies by co-targeting PMN-MDSCs	16
The role of TRIM25 in the occurrence and development of cancers and inflammatory diseases	16
Snake venom-derived peptides as anticancer candidates: Pioneering next-generation therapies	16
Unravelling the complexity of lncRNAs in autophagy to improve potential cancer therapy	16
Bioelectronic medicines: Therapeutic potential and advancements in next-generation cancer therapy	16
Interstitial fluid pressure as an emerging biomarker in solid tumors	16
Sensory neuro-tumor crosstalk: Therapeutic opportunities and emerging frontiers in cancer neuroscience	16
A review exploring the fusion of oncolytic viruses and cancer immunotherapy: An innovative strategy in the realm of cancer treatment	16
Relevance of tumor microbiome in cancer incidence, prognosis, and its clinical implications in therapeutics	16
Editorial Board	16
Mechanistic regulation of FOXO transcription factors in the nucleus	16
Therapeutic strategies of dual-target small molecules to overcome drug resistance in cancer therapy	16
Odors and cancer: Current status and future directions	16
Implication of Toll-Like Receptors in growth and management of health and diseases: Special focus as a promising druggable target to Prostate Cancer	16
Perioperative immunotherapy for patients with EGFR mutant non-small cell lung cancer: Unexpected potential benefits	16
microRNA-205 in prostate cancer: Overview to clinical translation	16
Precision medicine and phosphoproteomics for the identification of novel targeted therapeutic avenues in sarcomas	16
E3 ligases and deubiquitinating enzymes regulating the MAPK signaling pathway in cancers	15
Small extracellular vesicles (exosomes) and their cargo in pancreatic cancer: Key roles in the hallmarks of cancer	15
The progress of immune checkpoint therapy in primary liver cancer	15
Novel therapeutic approaches in GEP-NETs based on genetic and epigenetic alterations	15
Editorial Board	15
Targeting lipid metabolism to enhance cancer immunotherapy	15
Bacteria-based cancer therapy: Looking forward	15
Combination therapies with Wnt signaling inhibition: A better choice for prostate cancer treatment	15
Acetyl-CoA regulates lipid metabolism and histone acetylation modification in cancer	15
Cancer-associated fibroblasts: Mediators of head and neck tumor microenvironment remodeling	15
In vitro models: Can they unravel the complexities of cancer cell metastasis?	15
Biomechanical properties of laminins and their impact on cancer progression	15
Getting the GIST of long non-coding RNA	15
Corrigendum to “Unveiling the TGF-β/Smad signaling in renal carcinoma progression: Prognostic and therapeutic insights” [Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, Volume 1880, Issue 4,	15
RNF43 and ZNRF3: Versatile regulators at the membrane and their role in cancer	15
Dissecting the dual roles of lysosomal membrane proteins: Mediators of autophagy–apoptosis crosstalk in tumor progression	15
Key subunits of γ-secretase complex and breast cancer progression: biological function, regulation mode and therapeutic potential	15
Editorial Board	15
FGFR signaling and endocrine resistance in breast cancer: Challenges for the clinical development of FGFR inhibitors	15
Advancements in therapeutic peptides: Shaping the future of cancer treatment	14
Roles of miRNAs in regulating ovarian cancer stemness	14
Advancements in the application of ablative therapy and its combination with immunotherapy in anti-cancer therapy	14
Glioma and post-translational modifications: A complex relationship	14
The dual role of citrate in cancer	14
Fingerprint of the oxido-reductase ERO1: A protein disulfide bond producer and supporter of cancer	14
Targeting transposable elements in cancer: developments and opportunities	14
The innate effects of plant secondary metabolites in preclusion of gynecologic cancers: Inflammatory response and therapeutic action	14
Intercellular adhesion molecule-1 (ICAM-1): From molecular functions to clinical applications in cancer investigation	14
Decoding β-catenin associated protein-protein interactions: Emerging cancer therapeutic opportunities	13
The role of autophagy in pancreatic cancer progression	13
Gene regulation by the tumor suppressor p53 – The omics era	13
Clinical applications of deep learning in breast MRI	13
Spartin: At the crossroad between ubiquitination and metabolism in cancer	13
“Intrinsic disorder-protein modification-LLPS-tumor” regulatory axis: From regulatory mechanisms to precision medicine	13
Editorial Board	13
Charting the landscape of intratumoral microbiota in lung cancer: From bench to bedside	13
Efficacy and safety of trastuzumab with or without a tyrosine kinase inhibitor for HER2-positive breast cancer: A systematic review and meta-analysis	13
Exosomes: Traversing the blood-brain barrier and their therapeutic potential in brain cancer	13
Metabolic tricks of cancer cells	13
The association between the neuroendocrine system and the tumor immune microenvironment: Emerging directions for cancer immunotherapy	13