Cancer Letters

Papers
(The TQCC of Cancer Letters is 21. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Editorial Board191
Sphingosine-1 phosphate receptor 1 (S1PR1) expression maintains stemness of acute myeloid leukemia stem cells189
Versatility of Exosomes for Cancer Therapy181
Bypassing the Tollway; a novel path to TLR4 independent stemness regulation179
Ethnic Diversity and Metabolic Variations in Ovarian Cancer Cells: Implications for Personalized Medicine Strategies174
Editorial Board172
Corrigendum to “Selective degradation of FGFR1/2 overcomes antiestrogen resistance in ER+ breast cancer with FGFR1/2 alterations” [619 1 (2025) 217668 1–13]158
Corrigendum to “Identification of metastasis-associated proteins involved in gallbladder carcinoma metastasis by proteomic analysis and functional exploration of chloride intracellular channel 1” [Can146
Corrigendum to “Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells” [Cancer. Lett. (382) 2016-11-28; 382(2):215–230]146
Valproate and lithium: Old drugs for new pharmacological approaches in brain tumors?144
METTL3 regulates M6A methylation-modified EBV-pri-miR-BART3-3p to promote NK/T cell lymphoma growth132
Corrigendum to “The deficiency of ALKBH5 promotes lenvatinib resistance and CD8+ T cell exhaustion via accumulation of the cholesterol metabolite 27HC in hepatocellular carcinoma” [643 10 (2026) 21831132
Unscheduled polyploidy synergizes with oncogenic mutations to enhance genome instability and tumorigenesis127
Hormonal and neuronal interactions shaping the brain metastatic microenvironment123
A novel mismatch repair deficient lung adenocarcinoma model for immunotherapy research121
TIM3 on natural killer cells regulates antibody-dependent cellular cytotoxicity in HER2-positive gastric cancer117
ASPH dysregulates cell death and induces chemoresistance in hepatocellular carcinoma114
Editorial Board114
Nervous system in colorectal cancer109
The stromal microenvironment endows pancreatic neuroendocrine tumors with spatially specific invasive and metastatic phenotypes108
Neutrophil extracellular traps enhance platinum resistance in ovarian cancer via SHP-1 activation107
Targeting MKK3/c-Myc interaction to overcome osimertinib acquired resistance in EGFR mutant lung cancer107
A natural compound melatonin enhances the effects of Nimotuzumab via inhibiting EGFR in glioblastoma105
Regulation of gut microbiota on immune cell ferroptosis: A novel insight for immunotherapy against tumor103
Cigarette smoke induces FASN-dependent fatty acid metabolic rewiring to drive bladder cancer progression102
EGFR S442 ectodomain mutation confers cetuximab resistance that can be overcome by ERBB2 blockade with trastuzumab-deruxtecan98
Spatial multi-omics defines cancer-associated fibroblasts subtype gradients driving metabolic support and immune remodeling in pancreatic ductal adenocarcinoma96
Novel role of MKRN2 in regulating tumor growth through host microenvironment and macrophage M1 to M2 switch95
LCAT deficiency promotes hepatocellular carcinoma progression and lenvatinib resistance by promoting triglyceride catabolism and fatty acid oxidation94
Chaperone directed heterobifunctional molecules circumvent KRASG12C inhibitor resistance92
Increasing membrane polyunsaturated fatty acids sensitizes non-small cell lung cancer to anti-PD-1/PD-L1 immunotherapy92
Hypoxia effects on glioblastoma progression through YAP/TAZ pathway regulation92
CD147-specific chimeric antigen receptor T cells effectively inhibit T cell acute lymphoblastic leukemia91
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy88
FAP upregulates PD-L1 expression in cancer-associated fibroblasts to exacerbate T cells dysfunction and suppress anti-tumor immunity88
Intratumoral injection of mRNA encoding survivin in combination with STAT3 inhibitor stattic enhances antitumor effects87
Clinical development of immuno-oncology therapeutics85
ERBB3 targeting: A promising approach to overcoming cancer therapeutic resistance83
Fatty acids in cancer chemoresistance82
Neoantigen discovery and applications in glioblastoma: An immunotherapy perspective82
M6A-modified lncRNA FAM83H-AS1 promotes colorectal cancer progression through PTBP181
Coiled-coil domain-containing 154 promotes colorectal cancer proliferation and metastasis via interacting with minichromosome maintenance complex component 280
Manganese mediates nucleoplasm distribution of cGAS to enhance systemic antitumor immunity and drive abscopal effect80
Dual role of LY96 in shaping the mesenchymal glioblastoma ecosystem through stem cell maintenance and macrophage MES-like reprogramming79
PROTACs: Novel tools for improving immunotherapy in cancer79
Tumor-targeted exosomes for delivery of anticancer drugs78
Evaluation and preservation of fertility in patients with hematologic malignancies78
Sialic Acids: Sweet modulators fueling cancer cells and domesticating the tumor microenvironment77
The role of Hippo/YAP1 in cancer-associated fibroblasts: Literature review and future perspectives77
The E3 ligase TRIM22 functions as a tumor suppressor in breast cancer by targeting CCS for proteasomal degradation to inhibit STAT3 signaling76
Targeting LINC01607 sensitizes hepatocellular carcinoma to Lenvatinib via suppressing mitophagy75
The interplay between autophagy and apoptosis: its implication in lung cancer and therapeutics75
Targeting FOXM1 reshapes antitumor immunity to attenuate small cell lung cancer progression74
Proteomics and single cell profiling identify keratin driven preexisting immunity influences lung squamous carcinoma neoadjuvant therapy74
Targeting p53 for immune modulation: Exploring its functions in tumor immunity and inflammation73
Accelerating the clinical translation of CD70-targeted chimeric antigen receptor-based cell therapies in oncology: A comprehensive clinical investigation panorama analysis based on the Trialtrove data73
Tuning cellular metabolism for cancer virotherapy73
CD155 in tumor progression and targeted therapy70
Osteopontin promotes tumor microenvironment remodeling and therapy resistance70
MDSCs in bone metastasis: Mechanisms and therapeutic potential69
Comparable survival outcomes in HLA-Matched and haploidentical hematopoietic stem cell transplantation for severe aplastic anemia patients aged 40–50: A CBMTR Registry-based propensity score matching 69
An emerging aspect of cancer neuroscience: A literature review on chemotherapy-induced peripheral neuropathy68
Selpercatinib mitigates cancer cachexia independent of anti-tumor activity in the HT1080 tumor model68
The landscape of malignant transition: Unraveling cancer cell-of-origin and heterogeneous tissue microenvironment67
Integrated analysis of ascites and plasma extracellular vesicles identifies a miRNA-based diagnostic signature in ovarian cancer67
KAT7 enhances the proliferation and metastasis of head and neck squamous carcinoma by promoting the acetylation level of LDHA66
Letter to the editor on ‘A deep neural network predictor to predict the sensitivity of neoadjuvant chemoradiotherapy in locally advanced rectal cancer’65
Targeting Amino Acid Dependency for Cancer Treatment65
NSUN2-mediated m5C modification of KDM6B mRNA enhances osteoclast differentiation and promotes breast cancer bone metastasis65
Combination treatment with 17β-estradiol and anti-PD-L1 suppresses MC38 tumor growth by reducing PD-L1 expression and enhancing M1 macrophage population in MC38 colon tumor model65
AI-discovered cellular morphometric biomarkers in needle biopsy of prostate cancer predict neoadjuvant androgen deprivation therapy response and enable therapeutic targeting of mTOR in androgen depriv65
Nanoparticles in the diagnosis and treatment of cancer metastases: Current and future perspectives65
An effective two-stage NMBzA-induced rat esophageal tumor model revealing that the FAT-Hippo-YAP1 axis drives the progression of ESCC65
Extrachromosomal DNA amplifications exhibit distinct molecular characteristics and prognostic implications in gastric cancer64
R-spondin-3 promotes proliferation and invasion of breast cancer cells independently of Wnt signaling64
Loss of TFAM accelerates pentose phosphate pathway by unleashing G6PD oligomerization to drive hepatocarcinogenesis64
Corrigendum to “Discovery of YH677 as a cancer stemness inhibitor that suppresses triple-negative breast cancer growth and metastasis by regulating the TGFβ signaling pathway” [Canc. Lett. (2023) 216163
BCL-2/BCL-XL dual inhibition triggers Gasdermin D-mediated pyroptosis in mantle cell lymphoma63
Corrigendum to “UBE2T promotes radiation resistance in non-small cell lung cancer via inducing epithelial-mesenchymal transition and the ubiquitination-mediated FOXO1 degradation” [Canc. Lett. 494 (2063
Advancing neoadjuvant therapy with inetetamab for HER2-Positive breast cancer63
Tumor cell derived CCL20 exacerbates the immunosuppressive microenvironment by recruiting CCR6+ Tregs in pancreatic cancer62
FOXF2 expression triggered by endocrine therapy orchestrates therapeutic resistance through reorganization of chromatin architecture in breast cancer62
A high-affinity antibody-drug conjugates Actuximab-MMAE for potent and selective targeting of CEACAM5-Positive tumors61
Sonrotoclax (BGB-11417) synergistically amplifies the radiotherapy-elicited anti-tumor immune response61
MLCK inhibition induces synthetic lethality in MYC-driven cancer60
Lactylation-boosted polycomb repression of KLF4 elicits glycolysis in retinoblastoma: A positive feedback circuit between histone modifications60
Validation of “SARS-CoV-2 mRNA vaccines sensitize tumors to immune checkpoint blockade” in an independent cohort of 4,407 patients60
The combination of gemcitabine plus an anti-FGFR inhibitor can have a synergistic antitumor effect on FGF-activating cholangiocarcinoma60
Editorial Board60
MEK-mediated CHPF2 phosphorylation promotes colorectal cancer cell proliferation and metastasis by activating NF-κB signaling59
Uncontrolled hyperglycemia-induced membrane cholesterol dysregulation drives tumor immune evasion by reducing hardness of tumor cell plasma membrane58
Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases58
Emerging roles of lysosome homeostasis (repair, lysophagy and biogenesis) in cancer progression and therapy58
LKB1 inhibits telomerase activity resulting in cellular senescence through histone lactylation in lung adenocarcinoma58
G6PD+CSV+ circulating tumor cells associated with portal vein tumor thrombus formation via EMT-ferroptosis crosstalk: a dual biomarker for therapeutic efficacy and prognosis prediction in hepatocellul58
Deubiquitinating PABPC1 by USP10 upregulates CLK2 translation to promote tumor progression in pancreatic ductal adenocarcinoma57
Claudin-1 interacts with EPHA2 to promote cancer stemness and chemoresistance in colorectal cancer57
CircFLNB upregulated by chemotherapy via alternative splicing suppresses the progression of colorectal cancer56
Glucose restriction induces ROS-AMPK-mediated CTR1 expression and increases cisplatin efficiency in NSCLC56
Identification and characterization of Bufalin as a novel EGFR degrader56
Improved antitumor effects elicited by an oncolytic HSV-1 expressing a novel B7H3nb/CD3 BsAb55
Overexpression of nucleotide metabolic enzyme DUT in hepatocellular carcinoma potentiates a therapeutic opportunity through targeting its dUTPase activity55
Conquering chemoresistance in pancreatic cancer: Exploring novel drug therapies and delivery approaches amidst desmoplasia and hypoxia55
ANKZF1 knockdown inhibits glioblastoma progression by promoting intramitochondrial protein aggregation through mitoRQC55
Obese adipose tissue-derived extracellular vesicles enriched with glycolytic cargo promote colorectal cancer tumorigenesis55
S100A6 drives lymphatic metastasis of liver cancer via activation of the RAGE/NF-kB/VEGF-D pathway54
Copper orchestrates triple-negative breast cancer progression via the STEAP3-dependent CDK16-JAK1 activation54
Unraveling pancreatic ductal adenocarcinoma at single-cell resolution with spatial insights: From mechanisms to clinical translation53
Mapping the tumor immune landscape: single-cell RNA sequencing in cancer immunotherapy53
Low-dose metronomic chemotherapy triggers oxidized mtDNA sensing inside tumor cells to potentiate CD8+T anti-tumor immunity52
Acute myocardial infarction following allogeneic hematopoietic stem cell transplantation: A national cohort study52
WEE1 confers resistance to KRASG12C inhibitors in non-small cell lung cancer52
Tumor-nerve interactions in cancer regulation and progression52
Exercise in cancer prevention and anticancer therapy: Efficacy, molecular mechanisms and clinical information52
Single-cell RNA-sequencing of human spleens reveals an IDO-1+ tolerogenic dendritic cell subset in pancreatic cancer patients that is absent in normal individuals52
Pan-cancer atlas of tumor-resident microbiome, immunity and prognosis51
Protective role of epithelial deoxyhypusine synthase in colorectal carcinogenesis caused by deletion of the adenomatous polyposis coli gene51
WD repeat protein 54-mediator of ErbB2-driven cell motility 1 axis promotes bladder cancer tumorigenesis and metastasis and impairs chemosensitivity51
LINC00978 regulates metabolic rewiring to promote the malignancy of glioblastoma through AKR1B151
AI-based radiomic features predict outcomes and the added benefit of chemoimmunotherapy over chemotherapy in extensive stage small cell lung cancer: A multi-institutional study51
The feedback loop of AURKA/DDX5/TMEM147-AS1/let-7 drives lipophagy to induce cisplatin resistance in epithelial ovarian cancer51
Editorial Board50
Develop a Novel Therapy for Pancreatic Cancer50
Editorial Board50
Editorial Board50
Antimetastatic activity of B7-H3-targeted CAR T-cell therapy in triple-negative breast cancer49
A novel molecular subtyping based on multi-omics analysis for prognosis predicting in colorectal melanoma: A 16-year prospective multicentric study49
Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses48
Novel SARS-CoV-2 inhibition properties of the anti-cancer Kang Guan Recipe herbal formula48
Editorial Board47
Corrigendum to “P-REX1 amplification promotes progression of cutaneous melanomavia the PAK1/P38/MMP-2 pathway” [Cancer Lett. 407 (2017) 66–75]47
Active immunization with a structurally aggregated PD-L1 antigen breaks T and B immune tolerance in non-human primates and exhibits in vivo anti-tumoral effects in immunocompetent mouse tumor models47
Shifts in cancer funding: An overview of terminated research grants at the national cancer institute47
Interplay among extracellular vesicles, cancer stemness and immune regulation in driving hepatocellular carcinoma progression47
Multi-omics analysis unraveling stemness features associated with oncogenic dedifferentiation in 12 cancers47
PPAR agonists attenuate lenalidomide's anti-myeloma activity in vitro and in vivo47
FUT2-dependent fucosylation of LAMP1 promotes the apoptosis of colorectal cancer cells by regulating the autophagy-lysosomal pathway46
The CGCG response assessment criteria for spinal cord gliomas46
Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers46
Remodeling of tumor microenvironment by extracellular matrix protein 1a differentially regulates ovarian cancer metastasis46
Mitochondrial fragmentation in liver cancer: Emerging player and promising therapeutic opportunities46
Comprehensive clinico-genomic analysis of pancreatic ductal adenocarcinoma: Overcoming biases and limitations46
The role of the microbiota in cancer drug resistance and emerging therapeutic strategies46
Radiotherapy-induced tumor physical microenvironment remodeling to overcome immunotherapy resistance46
The safety and efficacy outcomes of Minnelide given alone or in combination with paclitaxel in advanced gastric cancer: A phase I trial46
Spermatid perinuclear RNA-binding protein promotes UBR5-mediated proteolysis of Dicer to accelerate triple-negative breast cancer progression45
Mucins as contrast agent targets for fluorescence-guided surgery of pancreatic cancer45
The post-chemotherapy changes of tumor physical microenvironment: Targeting extracellular matrix to address chemoresistance45
GPRC5A promotes gallbladder cancer metastasis by upregulating TNS4 via the JAK2–STAT3 pathway45
Phosphorylation of PBK/TOPK Tyr74 by JAK2 promotes Burkitt lymphoma tumor growth45
SENP1-Sirt3 axis promotes cholesterol biosynthesis in tumor-associated macrophages to suppress anti-tumor immunity44
Smoking-induced CCNA2 expression promotes lung adenocarcinoma tumorigenesis by boosting AT2/AT2-like cell differentiation44
Exosomal circUBR5 drives metastasis and chemoresistance in gastric signet-ring cell carcinoma by reprogramming cholesterol metabolism through the hsa-miR-1208/CYP19A1 axis and ACAT1 upregulation44
Decoding the potential microbiome modulation strategies from bugs to drugs in pancreatic cancer: Insights from clinical trials44
Suppressive immune microenvironment and CART therapy for glioblastoma: Future prospects and challenges43
CircUBE3A(2,3,4,5) promotes adenylate-uridylate-rich binding factor 1 nuclear translocation to suppress prostate cancer metastasis43
Single-cell chemokine receptor profiles delineate the immune contexture of tertiary lymphoid structures in head and neck squamous cell carcinoma43
Phase separation of EEF1E1 promotes tumor stemness via PTEN/AKT-mediated DNA repair in hepatocellular carcinoma43
Immunotherapy for extensive-stage small cell lung cancer: current status, challenges and future strategies43
Treatment strategies and molecular mechanism of radiotherapy combined with immunotherapy in colorectal cancer43
Application prospect of circular RNA-based neoantigen vaccine in tumor immunotherapy43
Dysregulation of autophagy in gastric carcinoma: Pathways to tumor progression and resistance to therapy43
Nanomaterials in crossroad of autophagy control in human cancers: Amplification of cell death mechanisms43
REDD1 is a determinant of the sensitivity of renal cell carcinoma cells to autophagy inhibition that can be therapeutically exploited by targeting PIM activity43
Sorbitol dehydrogenase induction of cancer cell necroptosis and macrophage polarization in the HCC microenvironment suppresses tumor progression42
Frontiers in pancreatic cancer on biomarkers, microenvironment, and immunotherapy42
hnRNPLL regulates MYOF alternative splicing and correlates with early metastasis in pancreatic ductal adenocarcinoma42
Disparities in mortality risk after diagnosis of hematological malignancies in 185 countries: A global data analysis42
Copper in hepatocellular carcinoma: A double-edged sword with therapeutic potentials42
A journey to excellence: Disseminating groundbreaking discoveries in oncology research42
Super-giant cells: Toward understanding tumor origins on the organismal level41
Effective leukemia-to-granulocyte induction by a cocktail of RUNX1, SPI1 and CEBPE41
The eIF3a translational control axis in the Wnt/β-catenin signaling pathway and colon tumorigenesis41
Deglycosylated PD-L1 is a biomarker for immune checkpoint blockade response: a real-world study in breast cancer patients in Taiwan41
Identification of SMARCAL1 as a molecular target for small cell lung cancer treatment41
Corrigendum to “NSUN4 mediated RNA 5-methylcytosine promotes the malignant progression of glioma through improving the CDC42 mRNA stabilization” [Cancer Lett. (2024) 597 217059]41
Corrigendum to “Scattered DUSP28 is a novel biomarker responsible for aggravating malignancy via the autocrine and paracrine signaling in metastatic pancreatic cancer” [Cancer Lett. 456 (2019 Aug 1) 141
Biodistribution and therapeutic efficacy of a gold nanoparticle-based targeted drug delivery system against pancreatic cancer41
Unlocking c-MET: A comprehensive journey into targeted therapies for breast cancer41
Hepatoprotective role for ERMP1 in MASLD-driven hepatocarcinogenesis and β-catenin-mutated tumors41
Corrigendum to “Helicobacter pylori upregulates Nanog and Oct4 via Wnt/β-catenin signaling pathway to promote cancer stem cell-like properties in human gastric cancer” [Canc. Lett. 374 (2016) 292–303]41
Deciphering the tumor-suppressive role of PSMB9 in melanoma through multi-omics and single-cell transcriptome analyses41
The mitotic regulator RCC2 promotes glucose metabolism through BACH1-dependent transcriptional upregulation of hexokinase II in glioma41
Melanoma cells release dysfunctional mitochondria to the tumor microenvironment and circulation in association with tumor progression41
A phase Ib/II trial of XL888 (HSP90 inhibitor) and pembrolizumab in metastatic pancreatic cancer with translational immune profiling41
Corrigendum to “The vulnerabilities of chemotherapy resistant pancreatic cancer revealed by organoids of pre- and post- neoadjuvant therapy” [Cancer Lett. (2026), Online ahead of print]41
RNA methyltransferase METTL16: From molecular mechanisms to therapeutic prospects in cancers40
Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells40
SIK1 promotes ferroptosis resistance in pancreatic cancer via HDAC5-STAT6-SLC7A11 axis40
Identification of SPP1+ macrophages in promoting cancer stemness via vitronectin and CCL15 signals crosstalk in liver cancer40
Dual targeting PPARα and NPC1L1 metabolic vulnerabilities blocks tumorigenesis40
CPSF3 regulates alternative polyadenylation of CNIH2 to promote esophageal squamous cell carcinoma progression40
Targeted inhibition of CHKα and mTOR in models of pancreatic ductal adenocarcinoma: A novel regimen for metastasis40
Targeting ephrin receptor A10 with antibody-drug conjugates for breast cancer40
Targeting tumor-intrinsic SLC16A3 to enhance anti-PD-1 efficacy via tumor immune microenvironment reprogramming40
Single-nucleus sequencing unveils heterogeneity in renal cell carcinomas microenvironment: Insights into pathogenic origins and treatment-responsive cellular subgroups39
Histone lactylation dynamics: Unlocking the triad of metabolism, epigenetics, and immune regulation in metastatic cascade of pancreatic cancer39
Keloids revisited: Current concepts in treatment and differential diagnosis39
CRISPR/Cas9 screen reveals that targeting TRIM34 enhances ferroptosis sensitivity and augments immunotherapy efficacy in hepatocellular carcinoma39
Revisiting the advances and challenges in the clinical applications of extracellular vesicles in cancer39
A novel GRK3-HDAC2 regulatory pathway is a key direct link between neuroendocrine differentiation and angiogenesis in prostate cancer progression39
EDARADD promotes colon cancer progression by suppressing E3 ligase Trim21-mediated ubiquitination and degradation of Snail39
PI3K PROTAC overcomes the lapatinib resistance in PIK3CA-mutant HER2 positive breast cancer39
Single-cell transcriptomics reveals intratumor heterogeneity and the potential roles of cancer stem cells and myCAFs in colorectal cancer liver metastasis and recurrence39
Circadian disruption in cancer and regulation of cancer stem cells by circadian clock genes: An updated review39
Enhanced prediction of breast cancer patient response to chemotherapy by integrating deconvolved expression patterns of immune, stromal and tumor cells39
Lipid metabolism reprogramming of CD8+ T cell and therapeutic implications in cancer39
Editorial Board38
Corrigendum to “Anti-tumor activity of antibody drug conjugate targeting aspartate-β-hydroxylase in pancreatic ductal adenocarcinoma” [Cancer Lett. 449 (2019) 87–98]38
Editorial Board38
MFN2-CD36 interaction regulates mitochondrial lipid digestion in cancer-associated fibroblasts and promotes esophageal squamous cell carcinoma progression38
How to design next-generation of antibody-drug conjugates for cancer treatment: Lessons from unsuccessful clinical trials38
Integrating multi-omics and artificial intelligence for personalized breast cancer management: A guide to clinicians38
Editorial Board38
PPDPF promotes esophageal squamous cell carcinoma progression by blocking PCCA binding to PCCB and inhibiting methionine catabolism38
Exosomal cannabidiol: A promising candidate for targeted oral delivery against breast cancer38
Radiosensitization of intrahepatic cholangiocarcinoma and metastatic disease in the liver using microbubble cavitation: results from a phase 2 clinical trial38
Corrigendum to “Pharmacological inhibition of DUSP6 suppresses gastric cancer growth and metastasis and overcomes cisplatin resistance” [Cancer Lett. (2018) 412 243–255]38
The intersections between neuroscience and medulloblastoma38
High-content drug screening in zebrafish xenografts reveals high efficacy of dual MCL-1/BCL-XL inhibition against Ewing sarcoma38
Targeting the molecular chaperone CCT2 inhibits GBM progression by influencing KRAS stability38
Editorial Board37
Multi-functional extracellular vesicles: Potentials in cancer immunotherapy37
Disruption of enhancer-driven S100A14 expression promotes esophageal carcinogenesis37
Drug screening reveals differential drug response in primary and metastatic clear cell sarcoma37
Editorial Board37
Inflammatory cytokine-regulated LNCPTCTS suppresses thyroid cancer progression via enhancing Snail nuclear export37
TFAP2C-DDR1 axis regulates resistance to CDK4/6 inhibitor in breast cancer37
MUC15 loss promotes perineural invasion in pancreatic cancer by activating the IGF1R/STAT3/NGF pathway37
Evolution and contemporary role of metronomic chemotherapy in the treatment of neuroblastoma37
IgSF protein EWI2 is a tumor suppressor37
The nuclear condensates of ESE3/EHF induce cellular senescence without the associated inflammatory secretory phenotype in pancreatic ductal adenocarcinoma37
Cell adhesion molecule ITGB2 promotes CAR-T cell therapy in B-cell malignancies37
Dual blockade of PD-1 and CTLA-4 generates long-lasting immunity against irradiated glioblastoma36
ITGB5 facilitates gastric cancer metastasis by promoting TGFBR2 endosomal recycling36
Cancer-associated fibroblast-like fibroblasts in vocal fold leukoplakia suppress CD8+T cell functions by inducing IL-6 autocrine loop and interacting with Th17 cells36
Cancer-associated fibroblasts: A key target to snatch victory from defeat in therapy resistance associated with the pancreatic cancer stroma36
Loss of branched-chain amino acid (BCAA) metabolism mediated by IGF2BP1-LPAL2-YBX1 interaction promotes malignancy in gallbladder cancer36
Cancer stem cells and tumor-associated macrophages: Interactions and therapeutic opportunities36
Metformin inhibits neutrophil extracellular traps-promoted pancreatic carcinogenesis in obese mice36
The new era of pancreatic cancer treatment: Application of nanotechnology breaking through bottlenecks35
ITPR1-AS1 promotes small cell lung cancer metastasis by facilitating P21 splicing and stabilizing DDX3X to activate the cRaf-MEK-ERK cascade35
HMGB1 in the interplay between autophagy and apoptosis in cancer35
SRC at the crossroads of KRAS inhibitor resistance: Mechanisms and therapeutic opportunities35
TGM2-mediated serotonylation in tumor endothelial cells promotes angiogenesis and tumor growth in colorectal cancer35
Extracellular vesicle biomarkers redefine prostate cancer radiotherapy35
Harnessing genetic interactions for prediction of immune checkpoint inhibitors response signature in cancer cells35
Microbiome and gartynecologic cancer35
AXL signal mediates adaptive resistance to KRAS G12C inhibitors in KRAS G12C-mutant tumor cells35
ETV4 lysine 2-hydroxyisobutyrylation promotes intrahepatic cholangiocarcinoma progression by suppressing ferroptosis through TXNIP downregulation35
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