Cancer Letters

Article	Citations
CircRNA in cancer: Fundamental mechanism and clinical potential	271
Immunotherapy for osteosarcoma: Fundamental mechanism, rationale, and recent breakthroughs	268
Clinical practice guidelines for the management of adult diffuse gliomas	226
Resveratrol for cancer therapy: Challenges and future perspectives	212
Incidence, mortality, survival, risk factor and screening of colorectal cancer: A comparison among China, Europe, and northern America	190
Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis	185
Regulation of Nuclear Factor-KappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis?	177
Long non-coding RNAs in the doxorubicin resistance of cancer cells	131
Triple-negative breast cancer therapeutic resistance: Where is the Achilles' heel?	128
Sonodynamic therapy-derived multimodal synergistic cancer therapy	120
Luteolin and its derivative apigenin suppress the inducible PD-L1 expression to improve anti-tumor immunity in KRAS-mutant lung cancer	120
HPV post-infection microenvironment and cervical cancer	118
Gut microbiota-derived short-chain fatty acids and colorectal cancer: Ready for clinical translation?	117
Pyruvate kinase M2 (PKM2) in cancer and cancer therapeutics	112
ACSL4 reprograms fatty acid metabolism in hepatocellular carcinoma via c-Myc/SREBP1 pathway	111
Metabolic adaptation in hypoxia and cancer	106
APOBEC: A molecular driver in cervical cancer pathogenesis	102
LncRNA-miRNA axes in breast cancer: Novel points of interaction for strategic attack	101
Autophagy and cancer drug resistance in dialogue: Pre-clinical and clinical evidence	100
Radiotherapy, immunotherapy, and the tumour microenvironment: Turning an immunosuppressive milieu into a therapeutic opportunity	100
LncRNAs in cancer: Regulatory and therapeutic implications	99
The oncogenic and clinical implications of lactate induced immunosuppression in the tumour microenvironment	97
CircRNAs in lung cancer - Biogenesis, function and clinical implication	96
Cancer-associated fibroblasts induce monocytic myeloid-derived suppressor cell generation via IL-6/exosomal miR-21-activated STAT3 signaling to promote cisplatin resistance in esophageal squamous cell	96
Translation of noncoding RNAs and cancer	94

METTL3 enhances the stability of MALAT1 with the assistance of HuR via m6A modification and activates NF-κB to promote the malignant progression of IDH-wildtype glioma	94
Phospholipase A2 superfamily in cancer	93
Epstein–Barr virus-associated gastric cancer: A distinct subtype	91
Wnt signaling pathway in cancer immunotherapy	91
Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids	90
Beta2-microglobulin(B2M) in cancer immunotherapies: Biological function, resistance and remedy	86
KLF2 inhibits cancer cell migration and invasion by regulating ferroptosis through GPX4 in clear cell renal cell carcinoma	85
M2 macrophage-derived exosomes promote lung adenocarcinoma progression by delivering miR-942	81
Exosomal circ_0030167 derived from BM-MSCs inhibits the invasion, migration, proliferation and stemness of pancreatic cancer cells by sponging miR-338-5p and targeting the Wif1/Wnt8/β-catenin axis	81
Exosome-derived FGD5-AS1 promotes tumor-associated macrophage M2 polarization-mediated pancreatic cancer cell proliferation and metastasis	80
Exosome-mediated delivery of RNA and DNA for gene therapy	80
Recent advances in strategies for overcoming hypoxia in photodynamic therapy of cancer	76
Fibronectin regulates anoikis resistance via cell aggregate formation	76
The TIM3/Gal9 signaling pathway: An emerging target for cancer immunotherapy	74
Targeting neutrophil extracellular traps with thrombomodulin prevents pancreatic cancer metastasis	73
NLRP3 inflammasome upregulates PD-L1 expression and contributes to immune suppression in lymphoma	72
Cancer screening in China: The current status, challenges, and suggestions	71
Tumor microenvironment mechanisms and bone metastatic disease progression of prostate cancer	71
Reality CHEK: Understanding the biology and clinical potential of CHK1	69
Metabolism and function of polyamines in cancer progression	66
Androgen receptor (AR) heterogeneity in prostate cancer and therapy resistance	65
Non-matrigel scaffolds for organoid cultures	65
Photodynamic therapy induces human esophageal carcinoma cell pyroptosis by targeting the PKM2/caspase-8/caspase-3/GSDME axis	65
Targeting the p53-MDM2 pathway for neuroblastoma therapy: Rays of hope	65
SLC7A11/ xCT is a target of miR-5096 and its restoration partially rescues miR-5096-mediated ferroptosis and anti-tumor effects in human breast cancer cells	64
A novel axis of circKIF4A-miR-637-STAT3 promotes brain metastasis in triple-negative breast cancer	64
Mesenchymal stem cell-derived exosome: A tumor regulator and carrier for targeted tumor therapy	64
Hippo pathway: Regulation, deregulation and potential therapeutic targets in cancer	64
Hypoxia: Friend or Foe for drug delivery in Pancreatic Cancer	63
Low-dose carboplatin reprograms tumor immune microenvironment through STING signaling pathway and synergizes with PD-1 inhibitors in lung cancer	62
CDK12/13 inhibition induces immunogenic cell death and enhances anti-PD-1 anticancer activity in breast cancer	62
Sonodynamic therapy: Rapid progress and new opportunities for non-invasive tumor cell killing with sound	62
SIRT3 inhibits gallbladder cancer by induction of AKT-dependent ferroptosis and blockade of epithelial-mesenchymal transition	62
The treatment landscape of metastatic prostate cancer	62
PMN-MDSCs accumulation induced by CXCL1 promotes CD8+ T cells exhaustion in gastric cancer	62
UBE2T promotes radiation resistance in non-small cell lung cancer via inducing epithelial-mesenchymal transition and the ubiquitination-mediated FOXO1 degradation	59
Celastrol in cancer therapy: Recent developments, challenges and prospects	59
Linc01232 promotes the metastasis of pancreatic cancer by suppressing the ubiquitin-mediated degradation of HNRNPA2B1 and activating the A-Raf-induced MAPK/ERK signaling pathway	59
Bacteroides fragilis restricts colitis-associated cancer via negative regulation of the NLRP3 axis	58
27-Hydroxycholesterol acts on myeloid immune cells to induce T cell dysfunction, promoting breast cancer progression	58
Tumor microenvironment in head and neck squamous cell carcinoma: Functions and regulatory mechanisms	58
A novel protein encoded by circASK1 ameliorates gefitinib resistance in lung adenocarcinoma by competitively activating ASK1-dependent apoptosis	58
Forkhead box D1 promotes EMT and chemoresistance by upregulating lncRNA CYTOR in oral squamous cell carcinoma	58
Hypoxia-mediated drug resistance in breast cancers	57
NK cells-directed therapies target circulating tumor cells and metastasis	57
The hexosamine biosynthetic pathway and cancer: Current knowledge and future therapeutic strategies	57
YAP/TAZ and EZH2 synergize to impair tumor suppressor activity of TGFBR2 in non-small cell lung cancer	56
The double-edged sword of H19 lncRNA: Insights into cancer therapy	55
Chitinase 3-like-1 and fibronectin in the cargo of extracellular vesicles shed by human macrophages influence pancreatic cancer cellular response to gemcitabine	55
Complement C5a induces the formation of neutrophil extracellular traps by myeloid-derived suppressor cells to promote metastasis	55

Interleukin-6 facilitates tumor progression by inducing ferroptosis resistance in head and neck squamous cell carcinoma	54
Hsp90 inhibitor-loaded IR780 micelles for mitochondria-targeted mild-temperature photothermal therapy in xenograft models of human breast cancer	54
Splicing factor SF3B1 is overexpressed and implicated in the aggressiveness and survival of hepatocellular carcinoma	54
T-cell-based immunotherapy in colorectal cancer	54
Epigenetic silencing of chemokine CCL2 represses macrophage infiltration to potentiate tumor development in small cell lung cancer	53
HNRNPC impedes m6A-dependent anti-metastatic alternative splicing events in pancreatic ductal adenocarcinoma	53
Immune checkpoint inhibitor resistance in hepatocellular carcinoma	53
Radiosensitivity of colorectal cancer and radiation-induced gut damages are regulated by gasdermin E	53
Different T-cell subsets in glioblastoma multiforme and targeted immunotherapy	52
IGFBP2 promotes tumor progression by inducing alternative polarization of macrophages in pancreatic ductal adenocarcinoma through the STAT3 pathway	52
FGF21 in obesity and cancer: New insights	52
Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells	51
Circulating RNAs in prostate cancer patients	51
SERPINE2/PN-1 regulates the DNA damage response and radioresistance by activating ATM in lung cancer	51
Gene fusion neoantigens: Emerging targets for cancer immunotherapy	51
Dissecting miRNA signature in colorectal cancer progression and metastasis	51
Fusobacterium nucleatum promotes esophageal squamous cell carcinoma progression via the NOD1/RIPK2/NF-κB pathway	51
Cooperation between chemotherapy and immunotherapy in gastroesophageal cancers	50
CircPTK2/PABPC1/SETDB1 axis promotes EMT-mediated tumor metastasis and gemcitabine resistance in bladder cancer	50
The transformation of cancer-associated fibroblasts: Current perspectives on the role of TGF-β in CAF mediated tumor progression and therapeutic resistance	49
Colorectal cancer immunotherapy-Recent progress and future directions	49
Exosomal O-GlcNAc transferase from esophageal carcinoma stem cell promotes cancer immunosuppression through up-regulation of PD-1 in CD8+ T cells	49
Stromal fibroblasts shape the myeloid phenotype in normal colon and colorectal cancer and induce CD163 and CCL2 expression in macrophages	49
CircARHGAP12 promotes nasopharyngeal carcinoma migration and invasion via ezrin-mediated cytoskeletal remodeling	49
Interferon regulatory factor 1(IRF-1) activates anti-tumor immunity via CXCL10/CXCR3 axis in hepatocellular carcinoma (HCC)	48
Tumor cell-derived exosomes deliver TIE2 protein to macrophages to promote angiogenesis in cervical cancer	48
Non-coding RNA in thyroid cancer - Functions and mechanisms	48
Glutaminase inhibition with telaglenastat (CB-839) improves treatment response in combination with ionizing radiation in head and neck squamous cell carcinoma models	48
Intestinal estrogen receptor beta suppresses colon inflammation and tumorigenesis in both sexes	47
FOXO3a in cancer drug resistance	47
Cope with copper: From copper linked mechanisms to copper-based clinical cancer therapies	47
Tumor perfusion enhancement by ultrasound stimulated microbubbles potentiates PD-L1 blockade of MC38 colon cancer in mice	46
APCCDC20-mediated degradation of PHD3 stabilizes HIF-1a and promotes tumorigenesis in hepatocellular carcinoma	46
Hypoxia-driven intratumor heterogeneity and immune evasion	46
An aptamer-based drug delivery agent (CD133-apt-Dox) selectively and effectively kills liver cancer stem-like cells	45
METTL3-m6A-EGFR-axis drives lenvatinib resistance in hepatocellular carcinoma	45
HOTAIR and androgen receptor synergistically increase GLI2 transcription to promote tumor angiogenesis and cancer stemness in renal cell carcinoma	45
Trials and tribulations of pancreatic cancer immunotherapy	45
Trim21-mediated HIF-1α degradation attenuates aerobic glycolysis to inhibit renal cancer tumorigenesis and metastasis	44
CD8+ T cell exhaustion and cancer immunotherapy	44
Fucoidan-coated nanoparticles target radiation-induced P-selectin to enhance chemoradiotherapy in murine colorectal cancer	44
Mitochondrial pyruvate carrier 1 regulates ferroptosis in drug-tolerant persister head and neck cancer cells via epithelial-mesenchymal transition	44
Plasmacytoid dendritic cells recruited by HIF-1α/eADO/ADORA1 signaling induce immunosuppression in hepatocellular carcinoma	44
LncRNAs in tumor metabolic reprogramming and immune microenvironment remodeling	44
p53-targeted lncRNA ST7-AS1 acts as a tumour suppressor by interacting with PTBP1 to suppress the Wnt/β-catenin signalling pathway in glioma	44
TOX-expressing terminally exhausted tumor-infiltrating CD8+ T cells are reinvigorated by co-blockade of PD-1 and TIGIT in bladder cancer	44
Immune checkpoints in osteosarcoma: Recent advances and therapeutic potential	43
Exosome-mediated transfer of SNHG7 enhances docetaxel resistance in lung adenocarcinoma	43
UHRF1 promotes androgen receptor-regulated CDC6 transcription and anti-androgen receptor drug resistance in prostate cancer through KDM4C-Mediated chromatin modifications	42
Fascin promotes lung cancer growth and metastasis by enhancing glycolysis and PFKFB3 expression	42
OTUD5-mediated deubiquitination of YAP in macrophage promotes M2 phenotype polarization and favors triple-negative breast cancer progression	42
HIF-1α inhibition promotes the efficacy of immune checkpoint blockade in the treatment of non-small cell lung cancer	42
Mitochondrial rewiring through mitophagy and mitochondrial biogenesis in cancer stem cells: A potential target for anti-CSC cancer therapy	42
Let-7a-5p inhibits triple-negative breast tumor growth and metastasis through GLUT12-mediated warburg effect	41
Macrophages in pancreatic cancer: An immunometabolic perspective	41
Non-coding RNAs in gastric cancer	41
Worldwide distribution, associated factors, and trends of gallbladder cancer: A global country-level analysis	41
PARPi treatment enhances radiotherapy-induced ferroptosis and antitumor immune responses via the cGAS signaling pathway in colorectal cancer	41
Unravelling glioblastoma heterogeneity by means of single-cell RNA sequencing	40
Exosome-mediated remodeling of the tumor microenvironment: From local to distant intercellular communication	40
The evolving role of immune cells in prostate cancer	40
Irreversible electroporation induces CD8+ T cell immune response against post-ablation hepatocellular carcinoma growth	40
Drug conjugate-based anticancer therapy - Current status and perspectives	40
Pericytes in the tumor microenvironment	40
Blood-based liquid biopsy: Insights into early detection and clinical management of lung cancer	39
MicroRNA-15b in extracellular vesicles from arsenite-treated macrophages promotes the progression of hepatocellular carcinomas by blocking the LATS1-mediated Hippo pathway	39
Prostate cancer dormancy and recurrence	39
Single cell RNA-seq reveals the CCL5/SDC1 receptor-ligand interaction between T cells and tumor cells in pancreatic cancer	39
An SGLT2 inhibitor modulates SHH expression by activating AMPK to inhibit the migration and induce the apoptosis of cervical carcinoma cells	39
Autophagy-driven regulation of cisplatin response in human cancers: Exploring molecular and cell death dynamics	39
Linking cell-surface GRP78 to cancer: From basic research to clinical value of GRP78 antibodies	39
Small extracellular vesicle-bound vascular endothelial growth factor secreted by carcinoma-associated fibroblasts promotes angiogenesis in a bevacizumab-resistant manner	38
Cancer-associated fibroblasts in non-small cell lung cancer: Recent advances and future perspectives	38
Intratumoral CD45+CD71+ erythroid cells induce immune tolerance and predict tumor recurrence in hepatocellular carcinoma	38
Integrated analysis of ascites and plasma extracellular vesicles identifies a miRNA-based diagnostic signature in ovarian cancer	38
Alterations of circulating bacterial DNA in colorectal cancer and adenoma: A proof-of-concept study	38
Long non-coding RNAs in colorectal cancer: Novel oncogenic mechanisms and promising clinical applications	37
Local intracerebral inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo	37
lncRNA LINC01057 promotes mesenchymal differentiation by activating NF-κB signaling in glioblastoma	37
Lymphatic metastasis of bladder cancer: Molecular mechanisms, diagnosis and targeted therapy	37

The human VRK1 chromatin kinase in cancer biology	37
TGF-β signaling networks in the tumor microenvironment	37
Tumor-stroma TGF-β1-THBS2 feedback circuit drives pancreatic ductal adenocarcinoma progression via integrin αvβ3/CD36-mediated activation of the MAPK pathway	37
miR-105-5p regulates PD-L1 expression and tumor immunogenicity in gastric cancer	37
Emerging immune checkpoints in the tumor microenvironment: Implications for cancer immunotherapy	37
MMP1 drives tumor progression in large cell carcinoma of the lung through fibroblast senescence	36
METTL3 induces PLX4032 resistance in melanoma by promoting m6A-dependent EGFR translation	36
SP1-induced lncRNA DUBR promotes stemness and oxaliplatin resistance of hepatocellular carcinoma via E2F1-CIP2A feedback	36
Circular RNA TGFBR2 acts as a ceRNA to suppress nasopharyngeal carcinoma progression by sponging miR-107	36
Sublethal heat stress-induced O-GlcNAcylation coordinates the Warburg effect to promote hepatocellular carcinoma recurrence and metastasis after thermal ablation	36
Adipocytokines visfatin and resistin in breast cancer: Clinical relevance, biological mechanisms, and therapeutic potential	36
Therapeutic targeting m6A-guided miR-146a-5p signaling contributes to the melittin-induced selective suppression of bladder cancer	36
STAT3β disrupted mitochondrial electron transport chain enhances chemosensitivity by inducing pyroptosis in esophageal squamous cell carcinoma	35
Cancer-associated fibroblasts activated by miR-196a promote the migration and invasion of lung cancer cells	35
MicroRNAs: Emerging oncogenic and tumor-suppressive regulators, biomarkers and therapeutic targets in lung cancer	35
Tumor microenvironment and metabolic remodeling in gemcitabine‐based chemoresistance of pancreatic cancer	35
Functional long non-coding RNAs in hepatocellular carcinoma	35
Bone marrow-derived macrophages converted into cancer-associated fibroblast-like cells promote pancreatic cancer progression	35
Racial disparities in prostate cancer: A complex interplay between socioeconomic inequities and genomics	35
Exosomes deliver lncRNA DARS-AS1 siRNA to inhibit chronic unpredictable mild stress-induced TNBC metastasis	34
Cedrol suppresses glioblastoma progression by triggering DNA damage and blocking nuclear translocation of the androgen receptor	34
Molecular characteristics and clinical behaviour of epithelial ovarian cancers	34
Prostate cancer treatment – China's perspective	34
Metabolism and polarization regulation of macrophages in the tumor microenvironment	34
Hippo/YAP signaling choreographs the tumor immune microenvironment to promote triple negative breast cancer progression via TAZ/IL-34 axis	34
Minimally invasive photothermal ablation assisted by laparoscopy as an effective preoperative neoadjuvant treatment for orthotopic hepatocellular carcinoma	34
CD74 promotes perineural invasion of cancer cells and mediates neuroplasticity via the AKT/EGR-1/GDNF axis in pancreatic ductal adenocarcinoma	34
Arginine deprivation as a strategy for cancer therapy: An insight into drug design and drug combination	34
Adipocyte-derived extracellular vesicles promote breast cancer cell malignancy through HIF-1α activity	33
Angiogenesis is promoted by exosomal DPP4 derived from 5-fluorouracil-resistant colon cancer cells	33
Interplay of long non-coding RNAs and HIF-1α: A new dimension to understanding hypoxia-regulated tumor growth and metastasis	33
Fangchinoline inhibits non-small cell lung cancer metastasis by reversing epithelial-mesenchymal transition and suppressing the cytosolic ROS-related Akt-mTOR signaling pathway	33
Nano-drug delivery system targeting tumor microenvironment: A prospective strategy for melanoma treatment	33
Sex differences in health and disease: A review of biological sex differences relevant to cancer with a spotlight on glioma	33
Stress-induced upregulation of TNFSF4 in cancer-associated fibroblast facilitates chemoresistance of lung adenocarcinoma through inhibiting apoptosis of tumor cells	33
Inhibition of glycolytic activator PFKFB3 suppresses tumor growth and induces tumor vessel normalization in hepatocellular carcinoma	33
Small hepatitis B virus surface antigen promotes malignant progression of hepatocellular carcinoma via endoplasmic reticulum stress-induced FGF19/JAK2/STAT3 signaling	33
IDO1/TDO dual inhibitor RY103 targets Kyn-AhR pathway and exhibits preclinical efficacy on pancreatic cancer	32
Understanding the cellular origin and progression of esophageal cancer using esophageal organoids	32
Deubiquitinating enzyme OTUB1 in immunity and cancer: Good player or bad actor?	32
Combining NanoKnife with M1 oncolytic virus enhances anticancer activity in pancreatic cancer	32
A novel integrated system using patient-derived glioma cerebral organoids and xenografts for disease modeling and drug screening	32
Targeted delivery of exosomal miR-484 reprograms tumor vasculature for chemotherapy sensitization	32
HNRNPA2B1 regulates tamoxifen- and fulvestrant-sensitivity and hallmarks of endocrine resistance in breast cancer cells	32
Sonodynamic therapy complements PD-L1 immune checkpoint inhibition in a murine model of pancreatic cancer	31
MUC4 enhances gemcitabine resistance and malignant behaviour in pancreatic cancer cells expressing cancer-associated short O-glycans	31
PARP inhibitor plus radiotherapy reshapes an inflamed tumor microenvironment that sensitizes small cell lung cancer to the anti-PD-1 immunotherapy	31
sORF-Encoded MicroPeptides: New players in inflammation, metabolism, and precision medicine	31
Metformin sensitizes AML cells to chemotherapy through blocking mitochondrial transfer from stromal cells to AML cells	31
The epigenetic roles of DNA N6-Methyladenine (6mA) modification in eukaryotes	31
Thyroid hormone and androgen signals mutually interplay and enhance inflammation and tumorigenic activation of tumor microenvironment in prostate cancer	31
TERT promoter mutations and GABP transcription factors in carcinogenesis: More foes than friends	31
c-Myc-activated intronic miR-210 and lncRNA MIR210HG synergistically promote the metastasis of gastric cancer	30
Differentiated cancer cell-originated lactate promotes the self-renewal of cancer stem cells in patient-derived colorectal cancer organoids	30
Tumor-derived microparticles promote the progression of triple-negative breast cancer via PD-L1-associated immune suppression	30
Inhibition of DCLK1 sensitizes resistant lung adenocarcinomas to EGFR-TKI through suppression of Wnt/β-Catenin activity and cancer stemness	30
Long noncoding RNA LINC00657 inhibits cervical cancer development by sponging miR-20a-5p and targeting RUNX3	30
The opportunities and challenges in immunotherapy: Insights from the regulation of PD-L1 in cancer cells	30
Secretory autophagy-induced bladder tumour-derived extracellular vesicle secretion promotes angiogenesis by activating the TPX2-mediated phosphorylation of the AURKA-PI3K-AKT axis	30
The intratumoral microbiome: Characterization methods and functional impact	30
Tumor-derived exosomes in the cancer immune microenvironment and cancer immunotherapy	30
Pyridoxine induces monocyte-macrophages death as specific treatment of acute myeloid leukemia	30
Chemotherapy in metastatic castration-resistant prostate cancer: Current scenario and future perspectives	30
Circular RNA circLGMN facilitates glioblastoma progression by targeting miR-127-3p/LGMN axis	29
XPO1 inhibition synergizes with PARP1 inhibition in small cell lung cancer by targeting nuclear transport of FOXO3a	29
Proton pump inhibitors suppress DNA damage repair and sensitize treatment resistance in breast cancer by targeting fatty acid synthase	29
Nanoparticles in the diagnosis and treatment of cancer metastases: Current and future perspectives	29
Co-administration of sulforaphane and doxorubicin attenuates breast cancer growth by preventing the accumulation of myeloid-derived suppressor cells	29
Sorafenib combined with STAT3 knockdown triggers ER stress-induced HCC apoptosis and cGAS-STING-mediated anti-tumor immunity	29
ILC2-derived IL-9 inhibits colorectal cancer progression by activating CD8+ T cells	29
Sox9/INHBB axis-mediated crosstalk between the hepatoma and hepatic stellate cells promotes the metastasis of hepatocellular carcinoma	29
VIRMA contributes to non-small cell lung cancer progression via N6-methyladenosine-dependent DAPK3 post-transcriptional modification	29
The Tn antigen promotes lung tumor growth by fostering immunosuppression and angiogenesis via interaction with Macrophage Galactose-type lectin 2 (MGL2)	29
Metabolic reprogramming by ex vivo glutamine inhibition endows CAR-T cells with less-differentiated phenotype and persistent antitumor activity	29
Immune-checkpoint inhibitor resistance in cancer treatment: Current progress and future directions	29
Tumor extracellular vesicles loaded with exogenous Let-7i and miR-142 can modulate both immune response and tumor microenvironment to initiate a powerful anti-tumor response	29
FGL2-wired macrophages secrete CXCL7 to regulate the stem-like functionality of glioma cells	29
Regulation of the tumor suppressor PTEN in triple-negative breast cancer	29
Dual inhibition of TGFβ signaling and CSF1/CSF1R reprograms tumor-infiltrating macrophages and improves response to chemotherapy via suppressing PD-L1	29
Breast cancer extracellular vesicles-derived miR-1290 activates astrocytes in the brain metastatic microenvironment via the FOXA2→CNTF axis to promote progression of brain metastases	28
Tumor-targeted exosomes for delivery of anticancer drugs	28
The tumor microenvironment shapes the molecular characteristics of exhausted CD8+ T cells	28
SMARCA4: Current status and future perspectives in non-small-cell lung cancer	28
Neutrophils: Driving inflammation during the development of hepatocellular carcinoma	28
A novel long non-coding RNA RP11-286H15.1 represses hepatocellular carcinoma progression by promoting ubiquitination of PABPC4	28
SIRT1 inhibitors mitigate radiation-induced GI syndrome by enhancing intestinal-stem-cell survival	28
Sunitinib increases the cancer stem cells and vasculogenic mimicry formation via modulating the lncRNA-ECVSR/ERβ/Hif2-α signaling	28
Exosomes in head and neck cancer: Roles, mechanisms and applications	28
E2F1 promotes proliferation and metastasis of clear cell renal cell carcinoma via activation of SREBP1-dependent fatty acid biosynthesis	28
Patient-derived organoids in translational oncology and drug screening	28
Calcium channel TRPV6 promotes breast cancer metastasis by NFATC2IP	28
Cancer-initiating cells in human pancreatic cancer organoids are maintained by interactions with endothelial cells	28
Developing liver organoids from induced pluripotent stem cells (iPSCs): An alternative source of organoid generation for liver cancer research	28
Androgens in prostate cancer: A tale that never ends	28
Small extracellular vesicles containing miR-192/215 mediate hypoxia-induced cancer-associated fibroblast development in head and neck squamous cell carcinoma	27