OOIR: Observatory of International Research

Papers

(The H4-Index of Cancer Letters is 63. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Editorial Board	186
Selpercatinib mitigates cancer cachexia independent of anti-tumor activity in the HT1080 tumor model	177
Versatility of Exosomes for Cancer Therapy	168
Sphingosine-1 phosphate receptor 1 (S1PR1) expression maintains stemness of acute myeloid leukemia stem cells	168
Bypassing the Tollway; a novel path to TLR4 independent stemness regulation	164
IBI379, a novel B cell maturation antigen/CD3 bispecific T-cell engager, displays high antitumor efficacy in preclinical models of multiple myeloma	154
Ethnic Diversity and Metabolic Variations in Ovarian Cancer Cells: Implications for Personalized Medicine Strategies	148
Editorial Board	144
Corrigendum to “Selective degradation of FGFR1/2 overcomes antiestrogen resistance in ER+ breast cancer with FGFR1/2 alterations” [619 1 (2025) 217668 1–13]	135
Corrigendum to “Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells” [Cancer. Lett. (382) 2016-11-28; 382(2):215–230]	134
Corrigendum to “Identification of metastasis-associated proteins involved in gallbladder carcinoma metastasis by proteomic analysis and functional exploration of chloride intracellular channel 1” [Can	127
CD147-specific chimeric antigen receptor T cells effectively inhibit T cell acute lymphoblastic leukemia	126
Combination treatment with 17β-estradiol and anti-PD-L1 suppresses MC38 tumor growth by reducing PD-L1 expression and enhancing M1 macrophage population in MC38 colon tumor model	118
Targeting FOXM1 reshapes antitumor immunity to attenuate small cell lung cancer progression	108
Valproate and lithium: Old drugs for new pharmacological approaches in brain tumors?	107
Hypoxia effects on glioblastoma progression through YAP/TAZ pathway regulation	106
The landscape of malignant transition: Unraveling cancer cell-of-origin and heterogeneous tissue microenvironment	105
Sialic Acids: Sweet modulators fueling cancer cells and domesticating the tumor microenvironment	104
Nervous system in colorectal cancer	103
LCAT deficiency promotes hepatocellular carcinoma progression and lenvatinib resistance by promoting triglyceride catabolism and fatty acid oxidation	102
Integrated analysis of ascites and plasma extracellular vesicles identifies a miRNA-based diagnostic signature in ovarian cancer	102
Manganese mediates nucleoplasm distribution of cGAS to enhance systemic antitumor immunity and drive abscopal effect	96
Novel role of MKRN2 in regulating tumor growth through host microenvironment and macrophage M1 to M2 switch	93
Intratumoral injection of mRNA encoding survivin in combination with STAT3 inhibitor stattic enhances antitumor effects	92
Increasing membrane polyunsaturated fatty acids sensitizes non-small cell lung cancer to anti-PD-1/PD-L1 immunotherapy	90

An emerging aspect of cancer neuroscience: A literature review on chemotherapy-induced peripheral neuropathy	90
FAP upregulates PD-L1 expression in cancer-associated fibroblasts to exacerbate T cells dysfunction and suppress anti-tumor immunity	89
The role of Hippo/YAP1 in cancer-associated fibroblasts: Literature review and future perspectives	89
A novel mismatch repair deficient lung adenocarcinoma model for immunotherapy research	88
ERBB3 targeting: A promising approach to overcoming cancer therapeutic resistance	88
MDSCs in bone metastasis: Mechanisms and therapeutic potential	87
Coiled-coil domain-containing 154 promotes colorectal cancer proliferation and metastasis via interacting with minichromosome maintenance complex component 2	87
NSUN2-mediated m5C modification of KDM6B mRNA enhances osteoclast differentiation and promotes breast cancer bone metastasis	82
Proteomics and single cell profiling identify keratin driven preexisting immunity influences lung squamous carcinoma neoadjuvant therapy	82
TIM3 on natural killer cells regulates antibody-dependent cellular cytotoxicity in HER2-positive gastric cancer	79
Evaluation and preservation of fertility in patients with hematologic malignancies	78
Chaperone directed heterobifunctional molecules circumvent KRASG12C inhibitor resistance	78
KAT7 enhances the proliferation and metastasis of head and neck squamous carcinoma by promoting the acetylation level of LDHA	77
Editorial Board	76
Targeting p53 for immune modulation: Exploring its functions in tumor immunity and inflammation	75
Fatty acids in cancer chemoresistance	74
ASPH dysregulates cell death and induces chemoresistance in hepatocellular carcinoma	74
Comparable survival outcomes in HLA-Matched and haploidentical hematopoietic stem cell transplantation for severe aplastic anemia patients aged 40–50: A CBMTR Registry-based propensity score matching	73
Neoantigen discovery and applications in glioblastoma: An immunotherapy perspective	73
Corrigendum to “The deficiency of ALKBH5 promotes lenvatinib resistance and CD8+ T cell exhaustion via accumulation of the cholesterol metabolite 27HC in hepatocellular carcinoma” [643 10 (2026) 21831	73
CD155 in tumor progression and targeted therapy	72
A Deep Learning Pathomic Signature Predicts Survival and Recurrence in Pancreatic Ductal Adenocarcinoma Independent of CA19-9	72
METTL3 regulates M6A methylation-modified EBV-pri-miR-BART3-3p to promote NK/T cell lymphoma growth	71
CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy	71
Targeted inhibition of the expression of both MCM5 and MCM7 by miRNA-214 impedes DNA replication and tumorigenesis in hepatocellular carcinoma cells	69
PI3K inhibitor impairs tumor progression and enhances sensitivity to anlotinib in anlotinib-resistant osteosarcoma	69
Tuning cellular metabolism for cancer virotherapy	68
Unscheduled polyploidy synergizes with oncogenic mutations to enhance genome instability and tumorigenesis	68
M6A-modified lncRNA FAM83H-AS1 promotes colorectal cancer progression through PTBP1	68
Hormonal and neuronal interactions shaping the brain metastatic microenvironment	68
A natural compound melatonin enhances the effects of Nimotuzumab via inhibiting EGFR in glioblastoma	67
The E3 ligase TRIM22 functions as a tumor suppressor in breast cancer by targeting CCS for proteasomal degradation to inhibit STAT3 signaling	66
Targeting LINC01607 sensitizes hepatocellular carcinoma to Lenvatinib via suppressing mitophagy	65
The stromal microenvironment endows pancreatic neuroendocrine tumors with spatially specific invasive and metastatic phenotypes	65
Tumor-targeted exosomes for delivery of anticancer drugs	64
Targeting MKK3/c-Myc interaction to overcome osimertinib acquired resistance in EGFR mutant lung cancer	64
Neutrophil extracellular traps enhance platinum resistance in ovarian cancer via SHP-1 activation	63
Regulation of gut microbiota on immune cell ferroptosis: A novel insight for immunotherapy against tumor	63
Clinical development of immuno-oncology therapeutics	63