Biophysical Chemistry

Article	Citations
Editorial Board	82
The Boltzmann principle in the theory of enzymatic catalysis and conformational mobility of biomolecules	71
Effect of cycloastragenol and punicalagin on Prp(106–126) and Aβ(25–35) oligomerization and fibrillizaton	58
Molecular insights into the transport and toxicity of 6-PPD: Interactions with human serum albumin and alpha-glucosidase	54
Studies on stabilization of collagen using Cr-doped polydopamine complex	48
Probing pharmaceutically important amino acids L-isoleucine and L-tyrosine Solubilities: Unraveling the solvation thermodynamics in diverse mixed solvent systems	45
A detailed review of genetically encodable RFPs and far-RFPs and their applications in advanced super-resolution imaging techniques	43
Disordered regions tune order in chromatin organization and function	37
Unveiling the mechanisms underlying photothermal efficiency of gold shell-isolated nanoparticles (AuSHINs) on ductal mammary carcinoma cells (BT-474)	36
Intrinsic disorder and structural biology: Searching where the light isn't	30
Editorial Board	25
Free energy landscape of wrapping of lipid nanocluster by polysaccharides	25
Molecular docking and density functional theory studies of flavonoids of Holy basil plant against COX-2 enzyme	24
In silico investigation on the mutational analysis of BRCA1-BARD1 RING domains and its effect on nucleosome recognition and ubiquitination	24
The contrasting roles of co-solvents in protein formulations and food products	21
The role of hydrophobic patches of de novo designed MSI-78 and VG16KRKP antimicrobial peptides on fragmenting model bilayer membranes	21
Dimethyl sulfoxide (DMSO) is a stabilizing co-solvent for G-quadruplex DNA	20
Interaction of gentamicin and gentamicin-AOT with poly-(lactide-co-glycolate) in a drug delivery system - density functional theory calculations and molecular dynamics simulation	20
Coupling of conformation and CPD damage in nucleosomal DNA	19
PolyQ aggregation studied by model peptides with intrinsic tryptophan fluorophores	18
Investigation of serotonin-receptor interactions, stability and signal transduction pathways via molecular dynamics simulations	18
Structural aspects of the MHC expression control system	18
The effect of various compounds on the COVID mechanisms, from chemical to molecular aspects	18
How to evict HP1 from H3: Using a complex salt bridge	17
Selective IR super-resolution imaging of β-keratins at the bulk or interface in feather detected by using a nonlinear optical process	17

Editorial Board	17
Quantification of protein-protein interactions and activation dynamics: A new path to predictive biomarkers	17
Corrigendum to “Effect of disialoganglioside GD3 on the subgel, gel and fluid phases of cationic DODAB vesicles” [biophysical chemistry 326 (2025) 107503]	16
Potential allosteric sites captured in glycolytic enzymes via residue-based network models: Phosphofructokinase, glyceraldehyde-3-phosphate dehydrogenase and pyruvate kinase	16
The amyloidogenic peptide stretch in human tau, tau306–311 is a promising injectable hydrogelator	16
Editorial Board	15
Infrared spectrochemical findings on intermittent fasting-associated gross molecular modifications in rat myocardium	15
Differential effect of polyol and sugar osmolytes on the refolding of homologous alpha amylases: A comparative study	15
Computational pharmacology: New avenues for COVID-19 therapeutics search and better preparedness for future pandemic crises	15
Editorial Board	14
Protein folding in vitro and in the cell: From a solitary journey to a team effort	14
Elucidation of benzene sulfonamide derivative binding at a novel interprotomer pocket of wild type and mutants of coxsackievirus B3 viral capsid using molecular dynamics simulations and density functi	14
The influence of N-alkyl chains in benzoyl-thiourea derivatives on urease inhibition: Soil studies and biophysical and theoretical investigations on the mechanism of interaction	14
Elucidating the conformational behavior and membrane-destabilizing capability of the antimicrobial peptide ecPis-4s	14
Atomic insights into the inhibition of R3 domain of tau protein by epigallocatechin gallate, quercetin and gallic acid	14
Different behavior of Ferguson plot between agarose and polyacrylamide gels	13
Editorial Board	13
Biochemical and biophysical properties of a recombinant serine peptidase from Purpureocillium lilacinum	13
Hydrogen‑deuterium exchange mass spectrometry to study interactions and conformational changes of proteins in paints	13
Exploring the aggregation of amyloid-β 42 through Monte Carlo simulations	13
Isolated auto-citrullinated regions of PADI4 associate to the intact protein without altering their disordered conformation	12
A deep learning framework for enhancer prediction using word embedding and sequence generation	12
Transient protonic capacitor: Explaining the bacteriorhodopsin membrane experiment of Heberle et al. 1994	12
C-terminal determinants for RNA binding motif 7 protein stability and RNA recognition	12
Decoding SARS-CoV-2 variants: Mutations, viral stability, and breakthroughs in vaccines and therapies	12
Discovery of TGFBR1 (ALK5) as a potential drug target of quercetin glycoside derivatives (QGDs) by reverse molecular docking and molecular dynamics simulation	12
Aβ42 fibril and non-fibril oligomers characterization using a nanopipette	12
Interdomain interactions in Grb2 revealed by the conformational stability and CD28 binding analysis	12
Next-generation antibacterial cryogels: Berberine-infused smart membranes with molecular docking-guided targeting of MRSA and MDR E. coli	12
Binding properties of recombinant LDL receptor and LOX-1 receptor to LDL measured using bio-layer interferometry and atomic force microscopy	11
Fifty-hertz magnetic fields induce DNA damage through activating mPTP associated mitochondrial permeability transition in senescent human fetal lung fibroblasts	11
DODAB vesicles containing lysophosphatidylcholines: The relevance of acyl chain saturation on the membrane structure and thermal properties	11
Self-assembling of coiled-coil peptides into virus-like particles: Basic principles, properties, design, and applications with special focus on vaccine design and delivery	11
Chemical modifications to mRNA nucleobases impact translation elongation and termination	11
Exploring the physicochemical properties of the integration of Tristearoyl uridine in Langmuir monolayers: An approach to cell membrane modeling for prodrugs	11
Characterization of plasmatic proteins adsorption on poly(styrene sodium sulfonate) functionalized silicone surfaces	11
NMR and EPR study of the interaction of tris(3-hydroxy-4-pyridinonato) Ga(III) complexes with liposomes that mimic plant membranes	10
Assessing the DNA structural integrity via selective annihilation of Watson-Crick hydrogen bonds: Insights from molecular dynamics simulations	10
Probing the ligand-binding pocket of recombinant β-lactoglobulin: Calorimetric and spectroscopic studies	10
The effect of lipid saturation on the formation of styrene maleic acid lipid nanoparticles	10
Organic solvents aggregating and shaping structural folding of protein, a case study of the protease enzyme	10
The membrane-binding bacterial toxin long direct repeat D inhibits protein translation	10
Structural dynamics of a designed peptide pore under an external electric field	9
Interaction of detergent with complex mimics of bacterial membranes	9
Protonic conductor: Explaining the transient “excess protons” experiment of Pohl's group 2012	9
Analyzing the interaction of Helicobacter pylori GAPDH with host molecules and hemin: Inhibition of hemin binding	9
A pipeline to evaluate the discrepant interactions between typical nitrogenous disinfection byproduct haloacetonitriles and human hemoglobin	9
Structural and mechanical behavior of type-I collagen fibrils in presence of induced electrostatic interactions through ionic liquids	9
Editorial Board	9
The B-box1 domain of PML mediates SUMO E2-E3 complex formation through an atypical interaction with UBC9	9

Excitation energy migration to study protein oligomerization and amyloid formation	9
Sugar distributions on gangliosides guide the formation and stability of amyloid-β oligomers	9
Simulated pressure changes in LacI suggest a link between hydration and functional conformational changes	8
The scientific adventures of Richard Epand	8
Oxidative damage to βL-crystallin in vitro by iron compounds formed in physiological buffers	8
ROC-guided virtual screening, molecular dynamics simulation, and bioactivity validation assessment Z195914464 as a 3CL Mpro inhibitor	8
A combination of structure-based virtual screening and experimental strategies to identify the potency of caffeic acid ester derivatives as SARS-CoV-2 3CLpro inhibitor from an in-house database	8
Editorial Board	8
Biophysical significance of fluorescence spectroscopy in deciphering nucleic acid dynamics: From fundamental to recent advancements	8
Crystal structure analysis of pyrrolidone carboxyl peptidase from Thermus thermophilus	8
The role of nonlinear axonal membrane capacitance in modulating ion channel cooperativity in action potential dynamics: Studies on Hodgkin-Huxley's model	8
Editorial Board	8
Computational design of a β-wrapin's N-terminal domain with canonical and non-canonical amino acid modifications mimicking curcumin's proposed inhibitory function	8
Interaction of Myrsinoic acid a with biomembrane models: Differential effects on DPPC and DPPS properties revealed by surface rheology and vibrational spectroscopy	8
Local optical probing of proteins of various sizes and charges with FITC label	8
Exploring the binding kinetics and behaviors of self-aggregated beta-amyloid oligomers to phase-separated lipid rafts with or without ganglioside-clusters	8
pH dependence of C•A, G•A and A•A mismatches in the stem of precursor microRNA-31	8
Editorial Board	8
The role of the lipid environment in the activity of G protein coupled receptors	7
A semiempirical and machine learning approach for fragment-based structural analysis of non-hydroxamate HDAC3 inhibitors	7
Evidence of the different effect of mercury and cadmium on the hIAPP aggregation process	7
Identification of determinants of lipid and ion transport in TMEM16/anoctamin proteins through a Bayesian statistical analysis	7
Biotransformation of phenytoin in the electrochemically-driven CYP2C19 system	7
Isolation of Amyloid-like Protein Aggregates (APA) from white bread and their characterisation	7
The composition of fusogenic lipid mixtures at the air-water modulates the physicochemical properties changes upon interaction with lysicamine	7
Thermodynamics of oligomerization and Helix-to-sheet structural transition of amyloid β-protein on anionic phospholipid vesicles	7
Metal-binding and folding thermodynamics of Escherichia coli ribonuclease HI related to its catalytic function	7
Editorial Board	7
Richer than previously probed: An application of 1H NMR reveals one hundred metabolites using only fifty microliter serum	7
Targeting hydrophobicity in biofilm-associated protein (Bap) as a novel antibiofilm strategy against Staphylococcus aureus biofilm	7
Identification of the therapeutic potential of novel TIGIT/PVR interaction blockers based advanced computational techniques and experimental validation	7
Tunnel connects lipid bilayer to occluded odorant-binding site of insect olfactory receptor	7
Editorial Board	7
Differential effects of DTT on HEWL amyloid fibrillation and fibril morphology at different pH	7
Effect of partial O-methylation in dehydrodieugenol on its antitrypanosomal activity - correlation with the toxicity using cell membrane models	7
The effect of human serum albumin glycation on the binding of antidiabetic agent-exenatide; the multispectroscopic studies. Part II	7
Secondary structure of peptides mimicking the Gly-rich regions of major ampullate spidroin protein 1 and 2	7
Molecular dynamics of SARS-CoV-2 omicron variants from Philippine isolates against hesperidin as spike protein inhibitor	7
Exploring the solubility and intermolecular interactions of biologically significant amino acids l-serine and L-cysteine in binary mixtures of H2O + DMF, H2O + DMSO and H2O + ACN in temperature range	7
How to best estimate the viscosity of lipid bilayers	7
Effects of curcumin in the interaction with cardiolipin-containg lipid monolayers and bilayers	7
Editorial Board	7
Mutations in asparaginase II from E. coli and implications for inactivation and PEGylation	7
Luteoloside inhibits Aβ1–42 fibrillogenesis, disintegrates preformed fibrils, and alleviates amyloid-induced cytotoxicity	7
Cationic liposomes as carriers of natural compounds from plant extract	6
pH-equilibration of human hair: Kinetics and pH-dependence of the partition ratios for H − and OH -ions based on a Freundlich isotherm	6
Lipid domain boundary triggers membrane damage and protein folding of human islet amyloid polypeptide in the early pathogenesis of amyloid diseases	6
Interaction mechanism of a cysteine protease inhibitor, odanacatib, with human serum albumin: In vitro and bioinformatics studies	6
Effects of an external static EF on the conformational transition of 5-HT1A receptor: A molecular dynamics simulation study	6
Nearest-neighbour parametrization of DNA single, double and triple mismatches at low sodium concentration	6
Unveiling theranostic potential: Insights into cell-free microRNA-protein interactions	6
Editorial Board	6
Salvianolic acid B prevents the amyloid transformation of A53T mutant of α-synuclein	6
Editorial Board	6
Asymmetrical interactions between nanoparticles and proteins arising from deformation upon adsorption to surfaces	6
Osmotic stress studies of G-protein-coupled receptor rhodopsin activation	6
Editorial Board	6
The influence of pH on the structure and stability of the Grb2 dimer reveals changes in the inter-domain and molecular interaction: Could it be a modulation mechanism?	6
Copper(II) enhances the antibacterial activity of nitroxoline against MRSA by promoting aerobic glycolysis	6
Structural packing of the non-amyloid component core domain in α-synuclein plays a role in the stability of the fibrils	6
Equilibrium solubility, solvent effect, solvation and thermodynamic modeling of 1, 3-dinitropyrazole in solutions of methyl alcohol /ethyl alcohol + water	6
Probing and gauging of D-Penicillamine xenobiotics in hepatic Wilson disease patients	6
Structural modeling, energetic analysis and molecular design of a π-stacking system at the complex interface of pediatric respiratory syncytial virus nucleocapsid with the C-terminal peptide of phosph	6
Liposomes encapsulating artificial cytosol as drug delivery system	6
Deterministic error propagation in ITC: Revealing multi-fold errors in Kd values under standard conditions	6
Hydrolysis rate constants of ATP determined in situ at elevated temperatures	6
Mechanistic and biophysical insight into the inhibitory and disaggregase role of antibiotic moxifloxacin on human lysozyme amyloid formation	6
Biocementation of soils of different surface chemistries via enzyme induced carbonate precipitation (EICP): An integrated laboratory and molecular dynamics study	6
Analyzing of L-tryptophan thermodynamics and its solubility in aqueous acetonitrile blends at diverse temperatures	6
Editorial Board	6
Combined effect of the head groups and alkyl chains of archaea lipids when interacting with bacteriorhodopsin	6
The pH dependence of emulsifying properties for glutathione disulfide at oil-water interfaces	6
Conformational stability and order of Hoogsteen base pair induced by protein binding	5
Design of zwitterionic fluorescent polymers for membrane protein solubilization into native nanodiscs	5
In silico analysis of aptamer-RNA conjugate interactions with human transferrin receptor	5
Composition of raft-like cell membrane microdomains resistant to styrene-maleic acid copolymer (SMA) solubilization	5
Bilirubin nanotechnology: An innovative approach in biomedicine	5
Photophysical and structural aspects of poly-L-tryptophan: π−π	5
Editorial Board	5
Decoding the dynamics of BCL9 triazole stapled peptide	5

Influence of docosahexaenoic acid on the interfacial behavior of cholesterol-containing lipid membranes: Interactions with small amphiphiles and hydration properties	5
A benchmark for evaluation of structure-based online tools for antibody-antigen binding affinity	5
Effect of a U:G mispair on the water around DNA	5
Editorial Board	5
A surprisingly simple three-state generic process for reversible protein denaturation by trifluoroethanol	5
Inhibitory effects of carbon quantum dots towards hen egg white lysozyme amyloidogenesis through formation of a stable protein complex	5
Urineprint of high-altitude: Insights from analyses of urinary biomarkers and bio-physical-chemical features of extracellular vesicles	5
Binding between an amine cationic surfactant and DNA and surface properties of the resultant aggregates	5
Interaction of negatively and positively capped gold nanoparticle with different lipid model membranes	5
Aggregation and partitioning of amyloid peptide fragments in the presence of a lipid bilayer: A coarse grained molecular dynamics study	5
Force-induced unzipping of DNA in the presence of solvent molecules	5
Allostery, and how to define and measure signal transduction	5
Editorial Board	5
Effects of perturbation of the hydrophobic coiled-coil core on the thermal transition process of α-helical self-assembling peptides with α-β conformational transition capability	5
Interaction process behind the strong stabilization of G-quadruplexes by alkaloid fagaronine	5
Improved analysis of NMR chemical shift perturbations through an error estimation method	5
Affinity of aromatic amino acid side chains in amino acid solvents	5
A single-molecule stochastic theory of protein-ligand binding in the presence of multiple unfolding/folding and ligand binding pathways	4
Development of immobilized peroxidase on amino-functionalized magnetic MgFe2O4 nanoparticles for antioxidant activity and decolorization	4
Non-micellar ganglioside GM1 induces an instantaneous conformational change in Aβ42 leading to the modulation of the peptide amyloid-fibril pathway	4
Editorial Board	4
Intrinsically disordered proteins/regions and insight into their biomolecular interactions	4
Serum albumin mitigated perfluorooctane sulfonate-induced cytotoxicity by affecting the cellular responses	4
Trp residues near peptide termini enhance the membranolytic activity of cationic amphipathic α-helices	4
An evidence of pores in phospholipid membrane induced by an antimicrobial peptide NK-2	4
Amyloids, amorphous aggregates and assemblies of peptides – Assessing aggregation	4
Analysis of solid-state NMR data facilitated by MagRO_NMRViewJ with Graph_Robot: Application for membrane protein and amyloid.	4
Theoretical investigation of the electronic absorption spectra of the glucosides	4
Studies on the binding of wedelolactone to human serum albumin with multi-spectroscopic analysis, molecular docking and molecular dynamic simulation	4
Editorial Board	4
Phenolic fractions of Heliotropium Bacciferum inhibit human insulin aggregation and protect against amyloid-induced cytotoxicity: Structural and biophysical analysis	4
Editorial for the special issue “A Celebration of Women in Biophysical Chemistry”	4
Editorial Board	4
Unbiased clustering of residues undergoing synchronous motions in proteins using NMR spin relaxation data	4
Dependence of cell's membrane potential on extracellular voltage observed in Chara globularis	4
A model of minimal entropy generation for cytoskeletal transport systems with multiple interacting motors	4
In silico and in vitro characterization of Phytolacca latbenia (Moq.): QSAR, phytochemical, and toxicological insights into antiglycation and antidiabetic potential	4
DNA groove binder and significant cytotoxic activity on human colon cancer cells: Potential of a dimeric zinc (II) phthalocyanine derivative	4
Neuroinflammation induced by amyloid-forming pancreatic amylin: Rationale for a mechanistic hypothesis	4
SDS protein interactions	4
The processing intermediate of human amylin, pro-amylin(1–48), has in vivo and in vitro bioactivity	4
Protein–lipid acyl chain interactions: Depth-dependent changes of segmental mobility of phospholipid in contact with bacteriorhodopsin	4
Radiation-induced alterations in the dielectric features of irradiated tissues	4
Nuclease resistance and protein recognition properties of DNA and hybrid PNA-DNA four-way junctions	4
The growth of microbial cultures complies with the laws of thermodynamics	4
A rhein-huprine hybrid protects erythrocyte membrane integrity against Alzheimer’s disease related Aβ(1-42) peptide	4
Characterization of the interaction of metal-protoporphyrins photosensitizers with β- lactoglobulin	4
Editorial Board	4
Quantum mechanics in ion channel	4
Molecular mechanisms of Lobeline-mediated inhibition of lysozyme amyloidogenesis: A synergistic approach using biophysical and cheminformatics techniques	4
Raman spectroscopic signatures of amyloid fibrils: Insights into structural and biochemical changes in human tissues	4
Decrypting the interaction pattern of Piperlongumine with calf thymus DNA and dodecamer d(CGCGAATTCGCG)2 B-DNA: Biophysical and molecular docking analysis	4
Spectroscopy studies of interaction hypericin with an anti-cancer therapy drug doxorubicin	4
Degree–based topological indices, NMR chemical shifts, chemical reactivity, molecular dynamics and DFT analysis of 1,4-Methanoazulene-9-methanol, Decahydro-4,8,8-trimethyl-, [1S-(1α,3aβ,4α,8aβ,9R)]	4
The food and pharmaceutical additive benzoic acid induces amyloid fibrillation of an intrinsically disordered protein	4
Nanoscale intracellular ultrastructures affected by osmotic pressure using small-angle X-ray scattering	4
Relevance of ceramide 1-phosphate domain formation in activation of cytosolic phospholipase A2	4
Citrullination of adenosine deaminase impairs its binding to dipeptidyl peptidase IV	4
Topical ocular administration using thermosensitive chitosan-glycerophosphate-PRP hydrogels for improved ocular bioavailability	4
A large HIV gp41 construct with trimer-of-hairpins structure exhibits V2E mutation-dominant attenuation of vesicle fusion and helicity very similar to V2E attenuation of HIV fusion and infection and s	4
Editorial Board	3
Effect of ergosterol or cholesterol on the morphology and dynamics of the POPC/sphingomyelin bilayer	3
Immature ALS-associated mutant superoxide dismutases form variable aggregate structures through distinct oligomerization processes	3
Modulating the pH-activity profile of the glucose isomerase from Thermotoga marimita by introducing positively and negatively charged residues	3
Exploring impact of cold atmospheric plasma directed self-assembly of glycated bovine serum albumin	3
Insights into the mechanism of peptide fibril growth on gold surface	3
Interaction of native and aggregated albumin with DMPC bilayers	3
Sustainable synthesis and functional profiling of Ipomoea hederifolia-derived terpenoids-assisted silver nanoparticles: Mechanistic insights into anticancer, antioxidant, antibiofilm, and anti-quorum	3
Editorial Board	3
Mapping the metabolic perturbations associated with palmitate-induced oxidative stress and development of insulin resistance in skeletal muscle cells	3
Structural factors governing binding of curvature-sensing peptides to bacterial extracellular vesicles covered with hydrophilic polysaccharide chains	3
A theoretical study on binding and stabilization of galactose and novel galactose analogues to the human α-galactosidase A variant causing Fabry disease	3
Characterisation of collagen type I matrices for pathophysiologically relevant spatial cancer cell cultures	3
Inhibition of nucleation and disruption of amyloid fibrillation in human lysozyme aggregation by a potent Cu(II) flufenamate chemotherapeutic drug candidate	3
Wine tannins and their aggregation/release with lipids and proteins: Review and perspectives for neurodegenerative diseases	3
Investigating the role of axonal ion channel cooperativity in action potential dynamics: Studies on Hodgkin-Huxley's model	3
Leveraging liquid-liquid phase separation and volume modulation to regulate the enzymatic activity of formate dehydrogenase	3
Fluorescence microscopic imaging of single desmin intermediate filaments elongated by the presence of divalent cations in vitro	3
Molecular crowding effect on specific binding of Hg2+ to T–T mismatched base pair in duplex DNA	3
Targeting phenylalanine assemblies as a prospective disease-modifying therapy for phenylketonuria	3
Detection of bacteriorhodopsin trimeric rotation at thermal phase transitions of purple membrane in suspension	3
Editorial Board	3
Analysis on the in-silico ensemble methods for 3D modelling of ssDNA aptamers	3
Energy landscapes for proteins described by the UNRES coarse-grained potential	3
Systematic molecular profiling of non-native N6-substitution effects on m6A binding to the YTH domains of human RNA m6A readers in diabetes	3
Membrane lateral organization from potential energy disconnectivity graph	3
Potential differentiation of successive SARS-CoV-2 mutations by RNA: DNA hybrid analyses	3
Alpha-synuclein phosphorylation induces amyloid conversion via enhanced electrostatic bridging: Insights from molecular modeling of the full-length protein	3
Understanding the conformational changes in the influenza B M2 ion channel at various protonation states	3
Dynamic membrane interaction and amyloid fibril formation of glucagon, melittin and human calcitonin	3
Bilirubin: Photophysical and photochemical properties, phototherapy, analytical methods of measurement. A short review	3
Editorial Board	3
Molecular recognition and interaction between human plasminogen Kringle 5 and voltage-dependent anion channel-1 by biological specificity technologies and molecular dynamic simulation	3
Equations describing semi-confluent cell growth (I) Analytical approximations	3
Monte Carlo molecular simulation of solution and surface-bound DNA hybridization of short oligomers at varying surface densities	3