OOIR: Observatory of International Research

Papers

(The TQCC of Allergologia et Immunopathologia is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
From bioinformatics to anti-inflammation and immune regulation: ACT001 in lipopolysaccharide-induced lung injury	28
From bench to bedside: advances in standardized oral immunotherapy and early predictors of persistent cow’s milk allergy in children	25
The Buddhasothorn Asthma Severity Score (BASS): A practical screening tool for predicting severe asthma exacerbations for pediatric patients	24
Regional patterns of molecular sensitization to dust mites and pollens in a Portuguese pediatric population: a multicentric study	20
Knockdown of KLK13 has a protective effect against ovalbumin-induced asthma in mice	20
Unveiling heterogeneity in individual thresholds	20
Quality of life in children with food allergies, psychiatric symptoms, and caregiving burden of their mothers	18
JNJ0966 inhibits PDGF-BB-induced airway smooth muscle cell proliferation and extracellular matrix production by regulating MMP-9	17
Study on the antipruritic mechanism of Zanthoxylum bungeanum and Zanthoxylum schinifolium volatile oil on chronic eczema based on H1R and PAR-2 mediated GRPR pathway	17
Activation of the NLRP3 inflammasome by HMGB1 through inhibition of the Nrf2/HO-1 pathway promotes bleomycin-induced pulmonary fibrosis after acute lung injury in rats	17
Sevoflurane ameliorates LPS-induced inflammatory injury of HK-2 cells through Sirtuin1/NF-κB pathway	16
Knockdown of CXCL3-inhibited apoptosis and inflammation in lipopolysaccharide-treated BEAS-2B and HPAEC through inactivating MAPKs pathway	16
Benefit of educational intervention on Autoinjector Technique for caregivers and paediatric patients with food allergies: A literature review	15
Aeroallergen sensitization in school-age children with allergic rhinitis	15
Allergic rhinitis and dental caries: A systematic review	14
lnc-THRIL and miR-125b relate to disease risk, severity, and imbalance of Th1 cells/Th2 cells in allergic rhinitis	14
Prevalence and triggers of allergic diseases across different age groups: A comparative analysis of patients aged under 50, 50–64, and 65 and older	13
IgE-mediated Anisakis allergy in children	13
ZBTB16 exerts anti-angiogenic effects in rheumatoid arthritis by regulating HIF-1α pathway	13
Impact of COVID-19 in allergen immunotherapy: An Italian survey	13
Severe bronchiolitis profiling as the first step towards prevention of asthma	13
Peucedanum japonicum Thunberg root extract inhibits atopic dermatitis-like skin symptoms	13
Consequence of COVID-19 on allergic asthma outcomes: a systematic review and meta-analysis	13
Diagnostic outcomes and temporal changes in skin tests and specific immunoglobulin E levels following Hymenoptera sting reactions: single-center analysis of 194 patients	13
Morroniside alleviates lipopolysaccharide-induced inflammatory and oxidative stress in inflammatory bowel disease by inhibiting NLRP3 and NF-κB signaling pathways	13

Biomarkers of response to omalizumab in patients with chronic spontaneous urticaria	13
Effect of budesonide combined with montelukast sodium on pulmonary function parameters and immunoglobulin levels in children with bronchial asthma	13
Management of antibiotic allergy in children: a practical approach	13
Knockdown of ARHGDIB promotes autophagy and reduces inflammation in LPS-induced alveolar epithelial cells via the PRKACB/NF-κB pathway	12
Sociodemographic characteristics of asthma patients and accompanying comorbidities	12
Erythropoietin inhibits neutrophil extracellular traps formation to ameliorate lung injury in a pneumonia model	11
Analysis of the diagnostic value of coagulation markers and coagulation function indices on the occurrence of DIC in sepsis and its prognosis	11
Anti-inflammatory effect of N-(trifluoromethylphenyl)- 2-cyano-3-hydroxy-crotonic acid amide and gluconic acid on allergic rhinitis and asthma controlling	11
Food allergy in adolescents: validation of the food allergy independent measure and the EuroPrevall food allergy quality of life questionnaire into Spanish	11
First successful desensitization with Abemaciclib in an adult patient with breast cancer: A case report	11
Retraction: MiR-185-5p measurement assists in reflecting Th1/Th2 cell imbalance, inflammatory cytokine production, and exacerbation risk for childhood asthma	11
Analysis of the efficacy of Yupingfeng powder combined with acupuncture on allergic rhinitis: systematic review and meta analysis	11
Long-term outcome of omalizumab-assisted desensitisation to cow’s milk and eggs in patients refractory to conventional oral immunotherapy: real-life study	11
Orientin inhibits the progression of fibroblast-like synovial cells in rheumatoid arthritis by regulating MAPK-signaling pathway	11
The role of Human Development Index in the epidemiology of asthma in adolescents in Kosovo	11
Investigation of serum IL-12, IL-16, and IL-17A as diagnostic biomarkers in children with cow’s milk protein allergy	10
The use of a long-acting muscarinic antagonist in the treatment of asthma: A tertiary asthma center experience	10
Critical appraisal of reporting, statistical methodology, and interpretation in a preclinical intranasal curcumin model of allergic rhinitis	10
Proteinase-3 as an autoantigen and the development of granulomatosis with polyangiitis	10
Correlation patterns among house dust mite allergens in allergic rhinitis: A molecular sensitization study in Mallorca	10
Tolerance induction to LTP in patients with anaphylaxis: Serological response markers	10
Real-World Study of Ragweed Sublingual Immunotherapy in Hungary	10
Selective IgA deficiency and allergic diseases: Clinical and immunological evaluation	10
Hierarchical analysis of Mediterranean Dietary pattern on atopic diseases’ prevalence in adolescence: The Greek Global Asthma Network study	10
ATP2B1-AS1 exacerbates sepsis-induced cell apoptosis and inflammation by regulating miR-23a-3p/TLR4 axis	10
Impulse oscillometry in children and adolescents with persistent asthma and its correlation with spirometry	9
Perinatal tobacco smoke exposure in 12,405 mother-infant pairs: findings from the EISL Phase 3 in South America	9
Mometasone furoate nasal spray in Italian children with seasonal allergic rhinitis: a comprehensive assessment	9
HLA-G in asthma and its potential as an effective therapeutic agent	9
Elucidating the probiotic strategy with Pediococcus acidilactici BCB1H and Lactiplantibacillus plantarum HMX2 for restoring normal functions of gut and suppressing inflammation in a DSS-induced coliti	9
Severity of disease and the quality of life indexes in infants with atopic dermatitis	9
Oral food challenge in children with contact urticaria in reaction to cow’s milk	9
Drug-induced enterocolitis, a new condition under consideration	9
Oral mite anaphylaxis after pizza consumption in a child: A case report and review of the literature	9
From triggers to treatment: An epidemiological exploration of anaphylaxis in a lower middle-income area in Colombia	9
Clinical and serological characteristics of patients allergic to LTP	9
A practical and applicable desensitization scheme for ciprofloxacin with a glass of water	9
Urolithin A induces protective autophagy to alleviate inflammation, oxidative stress, and endoplasmic reticulum stress in pediatric pneumonia	9
Is it time to reconsider the role of partially hydrolyzed infant formulas in the prevention of allergic diseases?	9
PHLDA1 knockdown inhibits inflammation and oxidative stress by regulating JNK/ERK pathway, and plays a protective role in sepsis-induced acute kidney injury	9
Food additives and their impact on human health	9
Old Questions, new answers: real-world long-term efficiency of hymenoptera venom immunotherapy: prevalance of venom-induced anaphylaxis, risk factors, and field sting reactions	9
Change of administration route of allergen immunotherapy: Rates and causes	9
Relapse or worsening of chronic spontaneous urticaria during SARS-CoV-2 infection and vaccination in children: A telemedicine follow-up	9
Association between the correct use of intranasal aerosols and symptom improvement in allergic rhinitis	9
Corrigendum to: Knockdown of ANXA3 regulates NF-κB/STAT3 pathway to alleviate inflammation and hyperproliferation in psoriasis models	9
Benralizumab in severe eosinophilic asthma: A real-world, single-center, observational study from Mexico	8
Effect of budesonide formoterol combined with tiotropium bromide on pulmonary function and inflammatory factors in patients with asthma–COPD overlap syndrome	8
Kaempferitrin alleviates LPS-induced septic acute lung injury in mice through downregulating NF-κB pathway	8
CTRP6 suppresses neutrophil extracellular traps formation to ameliorate sepsis-induced lung injury through inactivation of ERK pathway	8

Auraptene alleviates inflammatory injury and cell apoptosis in children with pneumonia in vitro	8
Analysis of the diagnostic value of coagulation markers and coagulation function indices on the occurrence of DIC in sepsis and its prognosis	8
CD4+CD25+CD127loFOXP3+ cell in food allergy: Does it predict anaphylaxis?	8
SIRT5 reduces the inflammatory response and barrier dysfunction in IL-17A-induced epidermal keratinocytes	8
Allergo-immunopathology mechanism of thymol-inhibiting airway remodeling in asthmatic mice by regulating TGF-β/Smad3 pathway	8
Decreased NK cells in cases of severe adenovirus pneumonia with liver dysfunction in pediatric intensive care unit: Evidence from 330 patients	8
Rhizoma coptidis can inhibit the excessive proliferation, inflammation, and transformation of lung fibroblasts into myofibroblasts	8
Protective effects of aloin on asthmatic mice by activating Nrf2/HO-1 pathway and inhibiting TGF-β/Smad2/3 pathway	8
LARP7 alleviates psoriasis symptoms in mice by regulating the SIRT1/NF-κκB signaling pathway	8
IgG food hypersensitivity: A potential hidden precipitant for chronic spontaneous urticaria A case report	8
Alpha-gal syndrome	7
Mesenchymal stem cell-derived exosomes improved septic lung injury by reducing excessive NETs formation and alleviating inflammatory response	7
Safety of 1 mcg/mL as the starting dose in cluster protocol for hymenoptera immunotherapy	7
Exploring the interplay between oxidative stress and autophagy in asthma: Pathophysiology and therapeutic potential	7
Long noncoding RNA HOXA-AS2 ameliorates chronic intermittent hypoxia-induced lung inflammation by regulating miR-17-5p/tipe2 axis	7
Quality of life against seasonal vs perennial allergens: ESPRINT-15 modified in the pediatric population	7
MiR-185-5p measurement assists in reflecting Th1/Th2 cell imbalance, inflammatory cytokine production, and exacerbation risk for childhood asthma	7
Risk of allergic rhinitis in patients with inflammatory bowel disease: A systematic review and meta-analysis	7
A rare outcome following a bee sting: Total alopecia	7
Galangin inhibits lipopolysaccharide-induced inflammation and stimulates osteogenic differentiation of bone marrow mesenchymal stem cells via regulation of AKT/mTOR signaling	7
Clinical use of ketoprofen lysine salt: a reappraisal in adolescents with acute respiratory infections	7
The immunopathology of coronary microembolization and the underlying inflammopathophysiological mechanisms	7
Microplastics exposure and immunologic response	7
Studying the relationship between allergo-inflammation and left atrium and pulmonary vein pathological changes in allergic asthma	7
The relationship between neutropenia and disease prognosis in patients with Common Variable Immunodeficiency (CVID)	7
Corrigendum to: Lysine hydroxylase 1 (PLOD1) regulates glucose metabolism and promotes Th17 cell differentiation in psoriasis	7
Vitamin A–regulated ciliated cells promote airway epithelium repair in an asthma mouse model	7
Recent advances in biologic therapies for ankylosing spondylitis: A 2024 update	6
Immunomodulatory effect of IL-2 induced bone marrow mononuclear cell therapy on control of allergic asthma	6
Early presentation of allergic contact dermatitis due to paraphenylenediamine	6
Knockdown of DDX3Y alleviates ovalbumin-induced allergic rhinitis in mice by regulating NF-κB pathway	6
A Delphi consensus on diagnosis, management, and treatment with allergen immunotherapy of polysensitized children in Spain	6
Positive drug provocation with beta-lactam antibiotics in children: A single test may not be enough	6
RE: Anaphylaxis due to green beans (Phaseolus vulgaris): a new phenotype?”	6
IgE-mediated allergy to egg protein	6
Real-life effectiveness of tezepelumab in severe asthma	6
Genetic predisposition and increased environmental allergen exposure in cat allergy: The pandemic is a very good example	6
Allergologia et Immunopathologia: The only way to move ahead is to grow	6
Significant association between TaqI and FokI VDR gene polymorphisms and chronic spontaneous urticaria in a Colombian Caribbean population	6
Acanthoside B attenuates NLRP3-mediated pyroptosis and ulcerative colitis through inhibition of tAGE/RAGE pathway	6
Factors affecting the use of salbutamol before hospital admission in children with asthma exacerbation	6
Appearance of food-dependent exercise-induced anaphylaxis as an inflammatory disease: a pediatric case report and differential diagnosis	6
Can fluoroquinolones be safely used in patients with immediate hypersensitivity reaction to penicillin?	6
Allergic contact dermatitis to chlorhexidine in children	6
Effect of metformin on gut microbiota imbalance in patients with T2DM, and the value of probiotic supplementation	6
Ragweed (Ambrosia artemisiifolia) is the most important seasonal allergen in the Black Sea Region	6
Auraptene alleviates inflammatory injury and cell apoptosis in children with pneumonia in vitro	6
Decreased expression of hsa-miR-142-3p and hsa-miR-155-5p in common variable immunodeficiency and involvement of their target genes and biological pathways	6
Wiskott-Aldrich syndrome complicated with IgG4-related Sclerosing disease: A case report and literature review	6
Isoegomaketone alleviates inflammatory response and oxidative stress in sepsis lung injury	6
Immediate reactions to proton pump inhibitors: Clinical findings and testing outcomes	6
Rosavin inhibits neutrophil extracellular traps formation to ameliorate sepsis-induced lung injury by regulating the MAPK pathway	6
Erythropoietin inhibits neutrophil extracellular traps formation to ameliorate lung injury in a pneumonia model	6
Revolutionizing leishmaniasis control: leveraging immunoinformatics for precision-driven in-silico vaccine design	6
Characterization of a group of children with eosinophilic esophagitis in Cali, Colombia	5
Cinnamtannin D1 ameliorates DSS-induced colitis by preventing Th17/Treg imbalance through activation of the AMPK/mTOR pathway	5
MiR-328-3p promotes TGF-β1-induced proliferation, migration, and inflammation of airway smooth muscle cells by regulating the PTEN/Akt pathway	5
Rapid drug desensitization with chemotherapy: when should omalizumab be considered?	5
Efficacy of hypertonic saline nasal irrigation in allergic rhinitis: A systematic review and meta-analysis	5
Neferine alleviates ovalbumin-induced asthma via MAPK signaling pathways in mice	5
SIRT3 improves alveolar epithelial cell damage caused by bronchopulmonary dysplasia through deacetylation of FOXO1	5
Zeaxanthin attenuates OVA-induced allergic asthma in mice by regulating the p38 MAPK/β-catenin signaling pathway	5
Outcomes of the European baseline series patch test in the geriatric population	5
Analysis of the diagnostic value of coagulation markers and coagulation function indices on the occurrence of DIC in sepsis and its prognosis	5
CITED2 alleviates lipopolysaccharide-induced inflammation and pyroptosis in - human lung fibroblast by inhibition of NF-κB pathway	5
Cold-induced anaphylaxis triggered by drinking cold water	5
Adult IgE-mediated food allergy: clinical characteristics, predictors of severe reactions, and total IgE cut-off	5
Etiological causes in patients with acute urticaria and angioedema	5
Prevalence of inhaled allergen sensitization among patients with suspected allergic diseases in Sichuan province: 3-year data from a single center	5
Therapeutic effects of acupuncture in rheumatoid arthritis are associated with centromere protein F expression	5
Molecular sensitisation patterns to aeroallergens in a Mediterranean paediatric population and their clinical implications	5
Simvastatin alleviates experimental autoimmune encephalomyelitis through regulating the balance of Th17 and Treg in mice	5
Lonicerin alleviates LPS-evoked inflammation and apoptosis in HK2 cells	5
Establishing the degree of control in patients with atopic dermatitis with the atopic dermatitis control tool (ADCT)	5