Biochimie

Papers
(The TQCC of Biochimie is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Zwitterionic fluorinated detergents: From design to membrane protein applications114
Deciphering the Akt1-HuD interaction in HuD-mediated neuronal differentiation87
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Melatonin as an adjuvant treatment modality with doxorubicin62
Circadian rhythmicity of the thioredoxin system in cultured murine peritoneal macrophages59
Cryptic inhibitory regions nearby activation domains56
Are Traditional mutant controls sufficient to identify true RNA G-quadruplex binding proteins?55
Proteomics of the haemolymph of the terrestrial crustacean Porcellio scaber reveals components of its innate immunity under baseline conditions53
Deciphering the substrate specificity of housekeeping sortase A and pilus-specific sortase C of probiotic bacterium Lactococcus lactis53
TolC-AcrA complex formation monitored by time dependent single-channel electrophysiology53
Intraovarian condensed platelet cytokines for infertility and menopause—Mirage or miracle?48
Death and the desaturase: Implication of Stearoyl-CoA desaturase-1 in the mechanisms of cell stress, apoptosis, and ferroptosis44
Bispecific targeting system based on DARPins-modified light-chain ferritin for cancer chemotherapy43
Human mitochondrial persulfide dioxygenase is potently and reversibly inhibited by nitric oxide39
The role of the gut microbial metabolism of sterols and bile acids in human health38
The copper P-type ATPase CtpA is involved in the response of Mycobacterium tuberculosis to redox stress33
Molecular and cellular outcomes of quercetin actions on healthy and tumor osteoblasts33
Potential elevation of exopeptidase activity of Glu-specific endopeptidase I/GluV8 mediated by hydrophobic P1′-position amino acid residue33
In silico activity and effect of synthetic chalcones on Candida albicans and Candida tropicalis biofilms30
Glycolysis as key regulatory step in FSH-induced rat Sertoli cell proliferation: Role of the mTORC1 pathway29
Molecular and cellular mechanisms of melatonin in breast cancer29
Elucidating the pivotal role of TSPO in porphyrin-related cellular processes, in Bacillus cereus28
Unveiling overlooked pathways: The uric acid catabolism genes in the human genome26
The role of mitochondrial DNA in bone/cartilage diseases26
Established and emerging players in phospholipid scrambling: A structural perspective26
New transaminase from Odontosyllis undecimdonta the first potential enzyme of the luciferin biosynthesis pathway25
Syndecan-1 and -4 influence Wnt signaling and cell migration in human breast cancers25
A U2 snRNP-specific protein, U2A′, is involved in stress response and drug resistance in Cryptococcus deneoformans25
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Translocator protein (TSPO), still an enigmatic transmembrane protein: From structures to functions24
Pyridoxal kinase gene deletion leads to impaired growth, deranged redox metabolism and cell cycle arrest in Leishmania donovani24
In-silico prioritization of pathogenic Interleukin-37b variants and a fusion platform for high-yield soluble production24
Lipids, from molecular mechanisms to diseases23
Comparison of the calcium signaling alterations in GABA-ergic medium spiny neurons produced from iPSCs of different origins23
Counteracting diabetes-induced adipose tissue derived-stromal cell senescence23
Enhanced activity of split trehalase biosensors by interspecies domain combineering23
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The interplay between cis- and trans-acting factors drives selective mRNA translation initiation in eukaryotes22
Ribosome biogenesis and homeostasis: in the front line to cope with cellular stress22
Dioclea violacea lectin inhibits tumorigenesis and tumor angiogenesis in vivo22
Purification and characterization of a hemocyanin with lectin-like activity isolated from the hemolymph of speckled shrimp, Metapenaeus monoceros21
Cold stress during room temperature housing alters skeletal response to simulated microgravity (hindlimb unloading) in growing female C57BL6 mice21
Transcriptional regulation of the Japanese flounder Cu,Zn-SOD (Jfsod1) gene in RAW264.7 cells during oxidative stress caused by causative bacteria of edwardsiellosis21
CogiTx1: A novel subtilisin A inhibitor isolated from the sea anemone Condylactis gigantea belonging to the defensin 4 protein family20
Coordination between human DNA polymerase β and apurinic/apyrimidinic endonuclease 1 in the course of DNA repair20
Multiple strategies for HB-EGF inhibition: interference with receptor binding, ectodomain shedding and matricrine signaling20
At the outer part of the active site in Trypanosoma cruzi glucokinase: The role of phenylalanine 33720
Application of transposon expression system in recombinant protein expression and gene therapy20
Zinc binding loop mutations of hSOD1 promote amyloid fibrils under physiological conditions: Implications for initiation of amyotrophic lateral sclerosis20
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Molecular insights of immune evasion by Orf Virus: the interaction and functional impact of viral OH1 phosphatase on STAT120
The glycoprotein gp63– a potential pan drug target for developing new antileishmanial agents19
Human prostacyclin and thromboxane synthases: Molecular interactions, regulation, and pharmacology19
The role of UCP5 in cardiac aging and metabolism in Drosophila19
Coumestrol as a new substance that may diminish lipid precursors of the inflammation in steatotic primary rat hepatocytes19
Glycine disrupts myelin, glutamatergic neurotransmission, and redox homeostasis in a neonatal model for non ketotic hyperglycinemia19
Crosstalk between protein misfolding and endoplasmic reticulum stress during ageing and their role in age-related disorders18
Enteroaggregative Escherichia coli induces altered glycosylation in membrane proteins of cultured human intestinal epithelial cells18
Enzymatic activity of HIV-1 protease defines migration of tumor cells in vitro and enhances their metastatic activity in vivo18
Functional and ligand binding studies of NAD(P)H hydrate dehydratase enzyme from vancomycin-resistant Staphylococcus aureus by NMR spectroscopic approach, including saturation transfer difference (STD18
Optimal transport model for gas migration in the intestinal wall18
Intestinal gluconeogenesis: A translator of nutritional information needed for glycemic and emotional balance18
Fibrinolytic enzyme from Arthrospira platensis and its effects on breast cancer cells: Exploring its potential as an innovative therapy17
Sterol biosynthesis and phytosterol bioconversion in Crassostrea gigas larvae: new evidence from mass-balance feeding studies17
Biochemical characterization of RNase R 2′-O-methylation sensitivity17
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Structural and functional properties of rBmTI-A: A Kunitz-BPTI serine protease inhibitor with therapeutical potential17
Structural and kinetic profiling of Leishmania braziliensis trypanothione reductase: A molecular model for the development of targeted therapies17
The unconventional RNA-binding activity of metabolic enzymes17
In silico-driven identification and experimental confirmation of antifungal proteins (AFPs) against Candida albicans16
Cytoskeletal β-tubulin and cysteine cathepsin L deregulation by SARS-CoV-2 spike protein interaction with the neuronal model cell line SH-SY5Y16
Stbd1-deficient mice display insulin resistance associated with enhanced hepatic ER-mitochondria contact16
Venomics and insect prey specificity of the Central American scorpion Centruroides limbatus (Pocock, 1898) and its comparison with close species Centruroides bicolor (Pocock, 1898)16
Novel alternative transcripts of TLR8 and TLR9 reveal evolutionary pressure to conserve protein structure16
Assessment of MGP gene expression in cancer and contribution to prognosis16
Probing telomeric-like G4 structures with full or partial 2′-deoxy-5-hydroxyuridine substitutions16
TSPO in pancreatic beta cells and its possible involvement in type 2 diabetes16
Revisiting SmE16, a calcium-binding protein from Schistosoma mansoni with unknown functions16
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The Mycobacterium tuberculosis protein tyrosine phosphatase MptpA features a pH dependent activity overlapping the bacterium sensitivity to acidic conditions15
Over-expression of AeWRKY2 promotes oleanolic acid and hederagenin accumulation in Aralia elata15
Materials and device architectures for cortisol detection: Mechanisms, measurement technologies, and clinical implications15
N-terminal PPE domain plays an integral role in extracellular transportation and stability of the immunomodulatory Rv3539 protein of the Mycobacterium tuberculosis15
The prolyl oligopeptidase and α-synuclein connection revisited15
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Decoding G-quadruplex stability: the role of loop architecture and sequence context in the human genome15
The β-lactam ticarcillin is a Staphylococcus aureus UDP-N-acetylglucosamine 2-epimerase binder15
Helicid: A novel Anti-Staphylococcus aureus adjuvant15
Effects of two longevity interventions, calorie restriction and rapamycin treatment, on the kynurenine-aryl hydrocarbon receptor pathway in aging skeletal muscle15
Venom variation among the three subspecies of the North African mountain viper Vipera monticola Saint Girons 195314
Dietary monoterpenoids and human health: Unlocking the potential for therapeutic use14
The unfolded protein response and the biology of uveal melanoma14
50 years since the concept of homeoviscous adaptation14
Corseting a tripartite ABC transporter to make it fit for transport14
p53 knock-down and hypoxia affects glutathione peroxidase 4 antioxidant response in hepatopancreas of the white shrimp Litopenaeus vannamei14
Interplay between cholesterol, Bis(monoacylglycerol)phosphate, and parasitophorous vacuole dynamics in Leishmania infantum infection of macrophages14
Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction14
Proton leak through the UCPs and ANT carriers and beyond: A breath for the electron transport chain14
LC-MS/MS based untargeted lipidomics uncovers lipid signatures of late-onset preeclampsia14
Exosomes, circadian rhythms, and cancer precision medicine: New frontiers14
Ribosome biogenesis is a therapeutic vulnerability in pediatric neuroblastoma14
Benefits of rutin on mitochondrial function and inflammation in an aluminum-induced neurotoxicity rat model: Potential interest for the prevention of neurodegeneration14
Structural study and antimicrobial and wound healing effects of lectin from Solieria filiformis (Kützing) P.W.Gabrielson13
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Ultrasensitive detection of microRNAs based on click chemistry-terminal deoxynucleotidyl transferase combined with CRISPR/Cas12a13
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Dynamic modulation of transthylakoid electric potential by chloroplast ATP synthases13
Elucidating on the quaternary structure of viper venom phospholipase A2 enzymes in aqueous solution13
Characterization of Arabidopsis thaliana FRATAXIN HOMOLOG in heme catabolism13
Melatonin as an oncostatic agent: Review of the modulation of tumor microenvironment and overcoming multidrug resistance13
MAGE-I proteins and cancer-pathways: A bidirectional relationship12
The impact of endocrine disrupting compounds and carcinogens in wastewater: Implications for breast cancer12
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Functional and immunological variability of Viperid venoms across continents and cross-neutralization by Peruvian antivenoms12
Interaction of Solanum tuberosum L. translation initiation factors eIF4E with potato virus Y VPg: Apprehend and avoid12
Hypothyroidism impacts mammary tumor-associated adipose tissue and breast cancer epithelial cell dialogue12
Interaction of small heat shock proteins with BAG312
Lrp as a potential transcriptional regulator involved in stress response in Haloferax mediterranei12
Integrated biomarker response index as an ally in the observation of metabolic biomarkers in muscle of Astyanax lacustris exposed to thermal variation12
Structural and functional studies of a snake venom phospholipase A2-like protein complexed to an inhibitor from Tabernaemontana catharinensis12
Glutathionylation and metabolic dysfunction-associated steatotic liver disease12
Lunatin-1: a membrane-disruptive peptide isolated from Hadruroides lunatus scorpion venom with cytotoxicity against MDA-MB-231 breast cancer cell line12
Voltage dependent anion channel and its interaction with N-acetyl-L-Cysteine (NAC) under oxidative stress on planar lipid bilayer12
Melatonin in health and diseases12
Daphnetin weakened the pathogenicity of methicillin-resistant Staphylococcus aureus by inhibiting Sortase A and α-hemolysin12
A novel metalloproteinase-derived cryptide from Bothrops cotiara venom inhibits angiotensin-converting enzyme activity12
Differential impact of copper stress in two Ectocarpales: metabolic disruption and defensive signaling in the free-living Ectocarpus sp7 and the endophytic Laminarionema elsbetiae11
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The extreme C-terminal region of the phage BFK20 gp41 helicase has a role in DNA binding, protein-ATP interactions and ATPase activity11
Heart and kidney H2S production is reduced in hypertensive and older rats11
Posttraumatic stress disorder is characterized by functional dysregulation of dermal fibroblasts11
Exploring mitochondrial phototoxicity: Mechanisms, measurement, and mitigation11
Recent advances in the use of legume lectins for the diagnosis and treatment of breast cancer11
Role of NADP+-dependent isocitrate dehydrogenase from muscle tissue of Rana sylvatica in ROS defense during freeze-tolerance11
Pathogenesis and therapeutic implications of matrix metalloproteinases in intervertebral disc degeneration: A comprehensive review11
Beyond classical domains: The protein unit paradigm - from protein-architecture characterization to downstream applications11
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Brain lipid sensing and the neural control of energy balance11
Functional characterization of GNE mutations prevalent in Asian subjects with GNE myopathy, an ultra-rare neuromuscular disorder11
Exploring ligand interactions with human phosphomannomutases using recombinant bacterial thermal shift assay and biochemical validation11
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Advances in cell cycle regulation to enhance recombinant protein production in CHO cells11
Regulation and signaling of SNX10, a tumor suppressor in hepatocellular carcinoma11
Luminescence-based complementation assay to assess target engagement and cell permeability of glycolate oxidase (HAO1) inhibitors11
Sucrose phosphorylase from Alteromonas mediterranea: Structural insight into the regioselective α-glucosylation of (+)-catechin11
Germline and somatic genetic variability of oxysterol-related genes in breast cancer patients with early disease of the luminal subtype10
CD38/NAD+ glycohydrolase and associated antigens in chronic lymphocytic leukaemia: From interconnected signalling pathways to therapeutic strategies10
A Malassezia pseudoprotease dominates the secreted hydrolase landscape and is a potential allergen on skin10
Role of the FhlA transcriptional activator in metabolic changes in Escherichia coli during fermentation of mixed carbon sources at acidic pH10
Retraction notice to “MiR-650 regulates the proliferation, migration and invasion of human oral cancer by targeting Growth factor independent 1 (Gfi1)” [Biochimie 156 (2018) 69–78]10
Naked mole-rat hyaluronan10
Humanizing plant-derived snakins and their encrypted antimicrobial peptides10
The tetrapartite synapse in neuropsychiatric disorders: Matrix metalloproteinases (MMPs) as promising targets for treatment and rational drug design10
Optimized high-yield expression of envelope glycoprotein domain III from dengue virus serotypes 1 to 410
Translocator protein (TSPO) ligands attenuate mitophagy deficits in the SH-SY5Y cellular model of Alzheimer's disease via the autophagy adaptor P6210
The ‘Not-So-Famous Five’ in tumorigenesis: tRNAs, tRNA fragments, and tRNA epitranscriptome in concert with AARSs and AIMPs10
Retraction notice to “Betulinic acid downregulates expression of oxidative stress-induced lipoprotein lipase via PKC/ERK/c-Fos pathways in RAW264.7 macrophages” [Biochimie 119C (2015) 192–203]10
The X Factor: Regional differences in the level of ontogenetic variations in procoagulant venom activity in the Northwestern Neotropical Rattlesnake (Crotalus culminatus)10
Lipid droplets degradation mechanisms from microalgae to mammals, a comparative overview10
Pigment epithelium-derived factor and its role in microvascular-related diseases10
Evaluating the cytotoxicity mechanism of the cell-penetrating peptide TP10 on Jurkat cells10
Reviewer Acknowledgement10
Mycobacterium tuberculosis and its secreted tyrosine phosphatases10
Enhancing amplification efficiency and reducing molecular diagnostic reaction time through rational design of T4 gp32 Variants in recombinase polymerase amplification10
Effect of metformin in hypothalamic astrocytes from an immunocompromised mice model9
Redesigning methionine γ-lyase for improved stability and catalytic activity in the β-elimination reaction for the synthesis of thiosulfinates9
Orchestra of ligand-activated transcription factors in the molecular symphony of SERPINE 1 / PAI-1 gene regulation9
CRISPR genotyping methods: Tracing the evolution from spoligotyping to machine learning9
The molecular crosstalk of the hippo cascade in breast cancer: A potential central susceptibility9
Macromolecules from mushrooms, venoms, microorganisms, and plants for diabetes treatment - Progress or setback?9
Leishmania (Viannia) braziliensis Thor strain and subpopulations Thor03, Thor10, and Thor22 have differences in the surface membrane proteases activity profile9
Characterization of the sweetness of natural plant-derived sweeteners mogroside IV and V and their interactions with human sweet taste receptor9
Achatina fulica haemocyanin-derived peptides as novel antimicrobial agents9
Galactokinase-like protein from Leishmania donovani: Biochemical and structural characterization of a recombinant protein9
Stability and context of intercalated motifs (i-motifs) for biological applications9
N-3 long-chain polyunsaturated fatty acids in fish physiology: From aquaculture to economic, ecological and public health challenges9
A clot to uncover: SARS-CoV-2 nucleocapsid can outcompete the FOXP3 forkhead domain for DNA binding in vitro9
Shift in phospholipid and fatty acid contents accompanies brain myelination9
N-terminal processing by dipeptidyl peptidase 9: Cut and Go!9
Unraveling the impact of the p.R107L mutation on the structure and function of human αB-Crystallin: Implications for cataract formation9
Editorial of the special issue “Tailored lipids: From synthesis to specific biological functions”9
Does hypersialylation compensate the functional Alpha1-AntiTrypsin (A1AT) deficiency in all critically ill patients?9
Modular architecture and functional annotation of human RNA-binding proteins containing RNA recognition motif9
Purification and characterization of human glycerol 3-phosphate dehydrogenases (mitochondrial and cytosolic) by NAD+/NADH redox method9
Cell cycle and mitosis progression during ZIKA virus infection: The viral non-structural protein NS5 as a master regulator of the APC/cyclosome?9
Modeling G4s in chromatin context confirms partial nucleosome exclusion and reveals nucleosome-disrupting effects of the least selective G4 ligands9
Microbial degradation of hydrocarbons from petroleum assisted by biosurfactants: Pathways and bioremediation potential9
Functions of long non-coding RNA ROR in patient-derived glioblastoma cells9
Structural descriptions of ligand interactions to RNA quadruplexes folded from the non-coding region of pseudorabies virus9
Flexibility of active center affects thermostability and activity of Penicillium canescens xylanase E8
Basic protein- and peptide-induced stabilization of long-loop DNA G-guadruplexes8
Effects of natural polymorphisms in SARS-CoV-2 RNA-dependent RNA polymerase on its activity and sensitivity to inhibitors in vitro8
Housing temperature plays a critical role in determining gut microbiome composition in research mice: Implications for experimental reproducibility8
Molecular explorations of the Leishmania donovani 6-phosphogluconolactonase enzyme, a key player in the pentose phosphate pathway8
The determinants of metabolic discrepancies in aerobic glycolysis: Providing potential targets for breast cancer treatment8
New insights into the substrate specificity of cholesterol oxidases for more aware application8
A single intra-articular injection of IDO-Gal3 shifts synovial fluid metabolic profiles for up to six weeks in male rats with knee instability8
Is insulin resistance tissue-dependent and substrate-specific? The role of white adipose tissue and skeletal muscle8
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Microbial β-glucosidases: Recent advances and applications8
ShortCut RNase III is capable of digesting single mRNA transcripts into < 10 nucleotide products8
Structure and function of Campylobacter jejuni polynucleotide phosphorylase (PNPase): Insights into the role of this RNase in pathogenicity8
Distinctive aspects of ligand binding to G4 DNA structure flanked by the double helix8
Biophysical investigations of class A GPCRs8
Role of dysfunctional peri-organ adipose tissue in metabolic disease8
Role of SIRT5 in cancer. Friend or Foe?8
Altered hemostatic dynamics and its regulation in follicular microenvironment of women with polycystic ovary syndrome8
Discovery and characterization of the α-amylases cDNAs from Enchytraeus albidus shed light on the evolution of “Enchytraeus-Eisenia type” Amy homologs in Annelida8
Sodium benzoate, a common food preservative-induced Insulin resistance and atrophy in C2C12 myotubes8
Anti-smoking drugs cytisine and varenicline reduce cardiac reperfusion injury in rat model of myocardial ischemia8
A site-specific phosphorylation in FSTL1 determines its promigratory role in wound healing8
Hypoxia-induced downregulation of RNA m6A protein machinery in the naked mole-rat heart8
Small molecular exogenous modulators of active forms of MMPs8
Glutathione is required for growth and cadmium tolerance in the amphibian chytrid fungus, Batrachochytrium dendrobatidis8
MicroRNA-mediated regulation of hypoxic kidney adaptation in naked mole-rats (Heterocephalus glaber)7
The mutual and dynamic role of TSPO and ligands in their binding process: An example with PK-111957
The pentose phosphate pathway (PPP) in the glioma metabolism: A potent enhancer of malignancy7
Adipokines from white adipose tissue in regulation of whole body energy homeostasis7
Exploring NAD+ metabolism and NNAT: Insights from structure, function, and computational modeling7
Difference in the rearrangement of quail histone H1 allelic variants during divergent selection for reduction of body mass coupled to the food withdraw7
Novel chimeric peptides based on endomorphins and ghrelin receptor antagonist produced supraspinal antinociceptive effects with reduced acute tolerance in mice7
The HEK293T cells manage overload by the overexpressed full-length Htt variants via proteasome activation7
Melatonin as an adjuvant treatment modality with doxorubicin [Biochimie 200 (2022) 1–7]7
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Sometimes size does matter: Anticoagulant pathophysiological effects of Southwestern Speckled Rattlesnake (Crotalus pyrrhus) venoms are dichotomous by body size7
Identification of an acetyl esterase in the supernatant of the environmental strain Bacillus sp. HR21-67
Solid-state NMR study of structural heterogeneity of the apo WT mouse TSPO reconstituted in liposomes7
Sialic acid-containing glycans play a role in the activity of snake venom proteases7
Evaluation of the effect of dimethyl fumarate on human bone marrow-derived mesenchymal stem cells using bottom-up proteomics7
Phototropin localization and interactions regulate photophysiological processes in Chlamydomonas reinhardtii7
Optimizing expression, purification, structural and functional assessments of a novel dimeric incretin (GLP-1cpGLP-1)7
In vitro and in vivo evidence of the antineoplastic activity of quercetin against endothelial cells transformed by Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor7
Biochemical and metabolic characterization of a G6PC2 inhibitor7
CRISPR/Cas9-mediated knock-out of AGXT1 in HepG2 cells as a new in vitro model of Primary Hyperoxaluria Type 17
A non-canonical, moonlighting Acinetobacter baumannii glyceraldehyde-3-phosphate dehydrogenase (GAPDH/GapA) promotes iron acquisition from heme, transferrin and lactoferrin7
Identification and characterisation of a novel interaction between oestrogen receptor alpha and FOXP27
Reporter system controlled by the involucrin promoter as a tool to follow epidermal differentiation7
Aerobic Exercise Attenuates Sarcopenia-Related Changes via TXNIP-Associated Modulation of Apoptosis, Inflammation and Autophagy7
Exercise-driven changes in tryptophan metabolism leading to healthy aging7
CRISPR/Cas9-mediated epigenetic editing tool: An optimized strategy for targeting de novo DNA methylation with stable status via homology directed repair pathway7
Mitochondrial proteases modulate mitochondrial stress signalling and cellular homeostasis in health and disease7
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