Biochimie

Article	Citations
The key role of aquaporins in animals and plants	154
The role of the gut microbial metabolism of sterols and bile acids in human health	84
Unveiling overlooked pathways: The uric acid catabolism genes in the human genome	48
Death and the desaturase: Implication of Stearoyl-CoA desaturase-1 in the mechanisms of cell stress, apoptosis, and ferroptosis	47
Deciphering the substrate specificity of housekeeping sortase A and pilus-specific sortase C of probiotic bacterium Lactococcus lactis	44
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Inside front cover-EDB	42
Deciphering the Akt1-HuD interaction in HuD-mediated neuronal differentiation	41
Dual-targeted anti-CMV/anti-HIV-1 heterodimers	41
Potential elevation of exopeptidase activity of Glu-specific endopeptidase I/GluV8 mediated by hydrophobic P1′-position amino acid residue	40
Molecular and cellular outcomes of quercetin actions on healthy and tumor osteoblasts	39
Knockdown of the mRNA encoding the ribosomal protein eL38 in mammalian cells causes a substantial reorganization of genomic transcription	39
New transaminase from Odontosyllis undecimdonta the first potential enzyme of the luciferin biosynthesis pathway	37
TolC-AcrA complex formation monitored by time dependent single-channel electrophysiology	36
Circadian rhythmicity of the thioredoxin system in cultured murine peritoneal macrophages	36
Cryptic inhibitory regions nearby activation domains	36
A U2 snRNP-specific protein, U2A′, is involved in stress response and drug resistance in Cryptococcus deneoformans	35
Cellular binding and uptake of fluorescent glucose analogs 2-NBDG and 6-NBDG occurs independent of membrane glucose transporters	34
The copper P-type ATPase CtpA is involved in the response of Mycobacterium tuberculosis to redox stress	34
Dynamics prediction of emerging notable spike protein mutations in SARS-CoV-2 implies a need for updated vaccines	31
Elucidating the pivotal role of TSPO in porphyrin-related cellular processes, in Bacillus cereus	31
Melatonin as an adjuvant treatment modality with doxorubicin	31
Glycolysis as key regulatory step in FSH-induced rat Sertoli cell proliferation: Role of the mTORC1 pathway	29
Involvement of aquaglyceroporins in energy metabolism in health and disease	29
Established and emerging players in phospholipid scrambling: A structural perspective	29

Intraovarian condensed platelet cytokines for infertility and menopause—Mirage or miracle?	29
Syndecan-1 and -4 influence Wnt signaling and cell migration in human breast cancers	29
Zwitterionic fluorinated detergents: From design to membrane protein applications	28
Proteomics of the haemolymph of the terrestrial crustacean Porcellio scaber reveals components of its innate immunity under baseline conditions	27
Molecular and cellular mechanisms of melatonin in breast cancer	26
Enhanced activity of split trehalase biosensors by interspecies domain combineering	25
Comparison of the calcium signaling alterations in GABA-ergic medium spiny neurons produced from iPSCs of different origins	25
Role of human group IIA secreted phospholipase A2 in malaria pathophysiology: Insights from a transgenic mouse model	25
Dioclea violacea lectin inhibits tumorigenesis and tumor angiogenesis in vivo	23
Purification and characterization of a hemocyanin with lectin-like activity isolated from the hemolymph of speckled shrimp, Metapenaeus monoceros	23
Counteracting diabetes-induced adipose tissue derived-stromal cell senescence	23
Glycine disrupts myelin, glutamatergic neurotransmission, and redox homeostasis in a neonatal model for non ketotic hyperglycinemia	22
Coumestrol as a new substance that may diminish lipid precursors of the inflammation in steatotic primary rat hepatocytes	22
Cold stress during room temperature housing alters skeletal response to simulated microgravity (hindlimb unloading) in growing female C57BL6 mice	22
Brown/Beige adipose tissues and the emerging role of their secretory factors in improving metabolic health: The batokines	21
Transcriptional regulation of the Japanese flounder Cu,Zn-SOD (Jfsod1) gene in RAW264.7 cells during oxidative stress caused by causative bacteria of edwardsiellosis	21
The interplay between cis- and trans-acting factors drives selective mRNA translation initiation in eukaryotes	20
Translocator protein (TSPO), still an enigmatic transmembrane protein: From structures to functions	20
Lipids, from molecular mechanisms to diseases	19
Coronaviruses, cholesterol and statins: Involvement and application for Covid-19	19
The glycoprotein gp63– a potential pan drug target for developing new antileishmanial agents	18
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Pyridoxal kinase gene deletion leads to impaired growth, deranged redox metabolism and cell cycle arrest in Leishmania donovani	17
Coordination between human DNA polymerase β and apurinic/apyrimidinic endonuclease 1 in the course of DNA repair	17
Cytoskeletal β-tubulin and cysteine cathepsin L deregulation by SARS-CoV-2 spike protein interaction with the neuronal model cell line SH-SY5Y	17
Inside front cover-EDB	17
At the outer part of the active site in Trypanosoma cruzi glucokinase: The role of phenylalanine 337	17
Enteroaggregative Escherichia coli induces altered glycosylation in membrane proteins of cultured human intestinal epithelial cells	17
G-quadruplex motifs are functionally conserved in cis-regulatory regions of pathogenic bacteria: An in-silico evaluation	17
Crosstalk between protein misfolding and endoplasmic reticulum stress during ageing and their role in age-related disorders	17
CogiTx1: A novel subtilisin A inhibitor isolated from the sea anemone Condylactis gigantea belonging to the defensin 4 protein family	17
Zinc binding loop mutations of hSOD1 promote amyloid fibrils under physiological conditions: Implications for initiation of amyotrophic lateral sclerosis	17
TSPO in pancreatic beta cells and its possible involvement in type 2 diabetes	16
Intraspecific venom variation of Mexican West Coast Rattlesnakes (Crotalus basiliscus) and its implications for antivenom production	16
Intestinal gluconeogenesis: A translator of nutritional information needed for glycemic and emotional balance	16
Assessment of MGP gene expression in cancer and contribution to prognosis	16
Crystal structure and characterization of nucleoside diphosphate kinase from Vibrio cholerae	16
Biochemical characterization of RNase R 2′-O-methylation sensitivity	16
Stbd1-deficient mice display insulin resistance associated with enhanced hepatic ER-mitochondria contact	16
Functional and ligand binding studies of NAD(P)H hydrate dehydratase enzyme from vancomycin-resistant Staphylococcus aureus by NMR spectroscopic approach, including saturation transfer difference (STD	16
The protein-bound uremic toxin p-cresyl-sulfate promotes intracellular ROS production and lipid peroxidation in 3T3-L1 adipose cells	16
Total mRNA and primary human myoblasts’ in vitro cell cycle progression distinguishes between clones	15
Probing telomeric-like G4 structures with full or partial 2′-deoxy-5-hydroxyuridine substitutions	15
Corseting a tripartite ABC transporter to make it fit for transport	15
Structural and functional properties of rBmTI-A: A Kunitz-BPTI serine protease inhibitor with therapeutical potential	15
Effects of osmolality on the expression of brain aquaporins in AQP11-null mice	15
Fibrinolytic enzyme from Arthrospira platensis and its effects on breast cancer cells: Exploring its potential as an innovative therapy	15
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Pathogenic role of mitogen activated protein kinases in protozoan parasites	15

Enzymatic activity of HIV-1 protease defines migration of tumor cells in vitro and enhances their metastatic activity in vivo	15
In silico-driven identification and experimental confirmation of antifungal proteins (AFPs) against Candida albicans	15
The Mycobacterium tuberculosis protein tyrosine phosphatase MptpA features a pH dependent activity overlapping the bacterium sensitivity to acidic conditions	14
Exosomes, circadian rhythms, and cancer precision medicine: New frontiers	14
Helicid: A novel Anti-Staphylococcus aureus adjuvant	14
Dynamic lid domain of Chloroflexus aurantiacus Malonyl-CoA reductase controls the reaction	14
50 years since the concept of homeoviscous adaptation	14
Dietary monoterpenoids and human health: Unlocking the potential for therapeutic use	13
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Benefits of rutin on mitochondrial function and inflammation in an aluminum-induced neurotoxicity rat model: Potential interest for the prevention of neurodegeneration	13
LC-MS/MS based untargeted lipidomics uncovers lipid signatures of late-onset preeclampsia	13
The β-lactam ticarcillin is a Staphylococcus aureus UDP-N-acetylglucosamine 2-epimerase binder	13
Venom variation among the three subspecies of the North African mountain viper Vipera monticola Saint Girons 1953	13
Poly(A) tail degradation in human cells: ATF4 mRNA as a model for biphasic deadenylation	13
The unfolded protein response and the biology of uveal melanoma	13
N-terminal PPE domain plays an integral role in extracellular transportation and stability of the immunomodulatory Rv3539 protein of the Mycobacterium tuberculosis	13
Structural study and antimicrobial and wound healing effects of lectin from Solieria filiformis (Kützing) P.W.Gabrielson	12
Melatonin as an oncostatic agent: Review of the modulation of tumor microenvironment and overcoming multidrug resistance	12
Ultrasensitive detection of microRNAs based on click chemistry-terminal deoxynucleotidyl transferase combined with CRISPR/Cas12a	12
A combinatorial in silico approach for microRNA-target identification: Order out of chaos	12
Proton leak through the UCPs and ANT carriers and beyond: A breath for the electron transport chain	12
The influence of friedelin, resinone, tingenone and betulin of compounds on chondrogenic differentiation of porcine adipose-derived mesenchymal stem cells (pADMSCs)	12
BAP31: Physiological functions and roles in disease	12
Dynamic modulation of transthylakoid electric potential by chloroplast ATP synthases	12
Structural and functional studies of a snake venom phospholipase A2-like protein complexed to an inhibitor from Tabernaemontana catharinensis	12
p53 knock-down and hypoxia affects glutathione peroxidase 4 antioxidant response in hepatopancreas of the white shrimp Litopenaeus vannamei	12
Human sperm functioning is related to the aquaporin-mediated water and hydrogen peroxide transport regulation	12
Inside front cover-EDB	12
Integrated biomarker response index as an ally in the observation of metabolic biomarkers in muscle of Astyanax lacustris exposed to thermal variation	12
Phospholipase A2, a nonnegligible enzyme superfamily in gastrointestinal diseases	11
Lrp as a potential transcriptional regulator involved in stress response in Haloferax mediterranei	11
A novel metalloproteinase-derived cryptide from Bothrops cotiara venom inhibits angiotensin-converting enzyme activity	11
MAGE-I proteins and cancer-pathways: A bidirectional relationship	11
Voltage dependent anion channel and its interaction with N-acetyl-L-Cysteine (NAC) under oxidative stress on planar lipid bilayer	11
Pathogenesis and therapeutic implications of matrix metalloproteinases in intervertebral disc degeneration: A comprehensive review	11
Mechanistic physicochemical insights into glycation and drug binding by serum albumin: Implications in diabetic conditions	11
Elucidating on the quaternary structure of viper venom phospholipase A2 enzymes in aqueous solution	11
Inside front cover-EDB	11
Characterization of Arabidopsis thaliana FRATAXIN HOMOLOG in heme catabolism	11
The impact of endocrine disrupting compounds and carcinogens in wastewater: Implications for breast cancer	11
Daphnetin weakened the pathogenicity of methicillin-resistant Staphylococcus aureus by inhibiting Sortase A and α-hemolysin	11
Interaction of small heat shock proteins with BAG3	11
Elucidating carbohydrate metabolism in Euglena gracilis: Reverse genetics-based evaluation of genes coding for enzymes linked to paramylon accumulation	11
Melatonin in health and diseases	11
Interaction of Solanum tuberosum L. translation initiation factors eIF4E with potato virus Y VPg: Apprehend and avoid	11
Key amino acid residues in homoserine-acetyltransferase from M. tuberculosis give insight into the evolution of MetX family of enzymes – HAT, SAT and HST	10
Recent advances in the use of legume lectins for the diagnosis and treatment of breast cancer	10
Posttraumatic stress disorder is characterized by functional dysregulation of dermal fibroblasts	10
Translocator protein (TSPO) ligands attenuate mitophagy deficits in the SH-SY5Y cellular model of Alzheimer's disease via the autophagy adaptor P62	10
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Role of NADP+-dependent isocitrate dehydrogenase from muscle tissue of Rana sylvatica in ROS defense during freeze-tolerance	10
Quench me if you can: Alpha-2-macroglobulin trypsin complexes enable serum biomarker analysis by MALDI mass spectrometry	10
Functional characterization of GNE mutations prevalent in Asian subjects with GNE myopathy, an ultra-rare neuromuscular disorder	10
Luminescence-based complementation assay to assess target engagement and cell permeability of glycolate oxidase (HAO1) inhibitors	10
Sucrose phosphorylase from Alteromonas mediterranea: Structural insight into the regioselective α-glucosylation of (+)-catechin	10
The tetrapartite synapse in neuropsychiatric disorders: Matrix metalloproteinases (MMPs) as promising targets for treatment and rational drug design	10
Heart and kidney H2S production is reduced in hypertensive and older rats	9
Optimized high-yield expression of envelope glycoprotein domain III from dengue virus serotypes 1 to 4	9
CD38/NAD+ glycohydrolase and associated antigens in chronic lymphocytic leukaemia: From interconnected signalling pathways to therapeutic strategies	9
The ‘Not-So-Famous Five’ in tumorigenesis: tRNAs, tRNA fragments, and tRNA epitranscriptome in concert with AARSs and AIMPs	9
Pigment epithelium-derived factor and its role in microvascular-related diseases	9
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Germline and somatic genetic variability of oxysterol-related genes in breast cancer patients with early disease of the luminal subtype	9
Exploring ligand interactions with human phosphomannomutases using recombinant bacterial thermal shift assay and biochemical validation	9
Reviewer Acknowledgement	9
Retraction notice to “MiR-650 regulates the proliferation, migration and invasion of human oral cancer by targeting Growth factor independent 1 (Gfi1)” [Biochimie 156 (2018) 69–78]	9
Mycobacterium tuberculosis and its secreted tyrosine phosphatases	9
Musculoskeletal regeneration: A zebrafish perspective	9
Bacillus thuringiensis: From biopesticides to anticancer agents	9
The role of G-Quadruplex DNA in Paraspeckle formation in cancer	9
Inside front cover-EDB	9
Evaluating the cytotoxicity mechanism of the cell-penetrating peptide TP10 on Jurkat cells	9
Retraction notice to “Betulinic acid downregulates expression of oxidative stress-induced lipoprotein lipase via PKC/ERK/c-Fos pathways in RAW264.7 macrophages” [Biochimie 119C (2015) 192–203]	9
Achatina fulica haemocyanin-derived peptides as novel antimicrobial agents	9
Structure and activation mechanism of the human liver-type glutaminase GLS2	9
Humanizing plant-derived snakins and their encrypted antimicrobial peptides	9
Brain lipid sensing and the neural control of energy balance	9
Ex vivo tolerization and M2 polarization of macrophages dampens both pro- and anti-inflammatory cytokine production in response to diabetic wound fluid stimulation	8
Unraveling the impact of the p.R107L mutation on the structure and function of human αB-Crystallin: Implications for cataract formation	8
Naked mole-rat hyaluronan	8

Functions of long non-coding RNA ROR in patient-derived glioblastoma cells	8
Structure and function of Campylobacter jejuni polynucleotide phosphorylase (PNPase): Insights into the role of this RNase in pathogenicity	8
Macromolecules from mushrooms, venoms, microorganisms, and plants for diabetes treatment - Progress or setback?	8
Kinetic and pharmacokinetic characteristics of therapeutic methinoninе γ-lyase encapsulated in polyion complex vesicles	8
Anti-smoking drugs cytisine and varenicline reduce cardiac reperfusion injury in rat model of myocardial ischemia	8
Cell cycle and mitosis progression during ZIKA virus infection: The viral non-structural protein NS5 as a master regulator of the APC/cyclosome?	8
A Malassezia pseudoprotease dominates the secreted hydrolase landscape and is a potential allergen on skin	8
Decreased cortical Nrf2 gene expression in autism and its relationship to thiol and cobalamin status	8
Characterizing ligand-induced conformational changes in clinically relevant galectin-1 by HN/H2O (D2O) exchange	8
Does hypersialylation compensate the functional Alpha1-AntiTrypsin (A1AT) deficiency in all critically ill patients?	8
N-terminal processing by dipeptidyl peptidase 9: Cut and Go!	8
Effect of metformin in hypothalamic astrocytes from an immunocompromised mice model	8
Galactokinase-like protein from Leishmania donovani: Biochemical and structural characterization of a recombinant protein	8
Editorial of the special issue “Tailored lipids: From synthesis to specific biological functions”	8
Lipid droplets degradation mechanisms from microalgae to mammals, a comparative overview	8
Shift in phospholipid and fatty acid contents accompanies brain myelination	8
The molecular crosstalk of the hippo cascade in breast cancer: A potential central susceptibility	8
Molecular explorations of the Leishmania donovani 6-phosphogluconolactonase enzyme, a key player in the pentose phosphate pathway	8
CRISPR genotyping methods: Tracing the evolution from spoligotyping to machine learning	8
Purification and characterization of human glycerol 3-phosphate dehydrogenases (mitochondrial and cytosolic) by NAD+/NADH redox method	8
Structural descriptions of ligand interactions to RNA quadruplexes folded from the non-coding region of pseudorabies virus	8
Orchestra of ligand-activated transcription factors in the molecular symphony of SERPINE 1 / PAI-1 gene regulation	8
Hypoxia-induced downregulation of RNA m6A protein machinery in the naked mole-rat heart	7
Solid-state NMR study of structural heterogeneity of the apo WT mouse TSPO reconstituted in liposomes	7
Fractionating stem cells secretome for Parkinson's disease modeling: Is it the whole better than the sum of its parts?	7
Crystallographic and biophysical analyses of Pseudomonas aeruginosa ketopantoate reductase: Implications of ligand induced conformational changes in cofactor recognition	7
Small molecular exogenous modulators of active forms of MMPs	7
Distinctive aspects of ligand binding to G4 DNA structure flanked by the double helix	7
Inside front cover-EDB	7
Microbial β-glucosidases: Recent advances and applications	7
Housing temperature plays a critical role in determining gut microbiome composition in research mice: Implications for experimental reproducibility	7
Modeling G4s in chromatin context confirms partial nucleosome exclusion and reveals nucleosome-disrupting effects of the least selective G4 ligands	7
Structural and mechanistic insights into the substrate specificity and hydrolysis of GH31 α-N-acetylgalactosaminidase	7
Biophysical investigations of class A GPCRs	7
Identification and characterisation of a novel interaction between oestrogen receptor alpha and FOXP2	7
The determinants of metabolic discrepancies in aerobic glycolysis: Providing potential targets for breast cancer treatment	7
Role of dysfunctional peri-organ adipose tissue in metabolic disease	7
Inside front cover-EDB	7
Discovery and characterization of the α-amylases cDNAs from Enchytraeus albidus shed light on the evolution of “Enchytraeus-Eisenia type” Amy homologs in Annelida	7
Stability and context of intercalated motifs (i-motifs) for biological applications	7
Redesigning methionine γ-lyase for improved stability and catalytic activity in the β-elimination reaction for the synthesis of thiosulfinates	7
Basic protein- and peptide-induced stabilization of long-loop DNA G-guadruplexes	7
α-Conotoxin RgIA and oligoarginine R8 in the mice model alleviate long-term oxaliplatin induced neuropathy	7
Glutathione is required for growth and cadmium tolerance in the amphibian chytrid fungus, Batrachochytrium dendrobatidis	7
Characterization of three sialidases from Danio rerio	7
Is insulin resistance tissue-dependent and substrate-specific? The role of white adipose tissue and skeletal muscle	7
Role of SIRT5 in cancer. Friend or Foe?	7
Flexibility of active center affects thermostability and activity of Penicillium canescens xylanase E	7
A site-specific phosphorylation in FSTL1 determines its promigratory role in wound healing	7
New insights into the substrate specificity of cholesterol oxidases for more aware application	7
HIV-1 Tat: An update on transcriptional and non-transcriptional functions	7
Modular architecture and functional annotation of human RNA-binding proteins containing RNA recognition motif	7
Effects of natural polymorphisms in SARS-CoV-2 RNA-dependent RNA polymerase on its activity and sensitivity to inhibitors in vitro	7
Glucose deprivation using 2-deoxyglucose and acarbose induce metabolic oxidative stress and apoptosis in female mice bearing breast cancer	7
The neutralisation and inhibitory effects of new tRNA-mimetic aptamer against cytotoxin-induced cytotoxicity in human skin keratinocytes	6
Aquaporins implicated in the cell proliferation and the signaling pathways of cell stemness	6
The l-Arginine pathway may act as a mediator in the association between impaired one-carbon metabolism and hypertension	6
Uncovering a delicate balance between endonuclease RNase III and ribosomal protein S15 in E. coli ribosome assembly	6
Regenerative medicines: A new regulatory paradigm for South Africa	6
Optimizing expression, purification, structural and functional assessments of a novel dimeric incretin (GLP-1cpGLP-1)	6
Corrigendum to “Wrapping axons in mammals and Drosophila: Different lipids, same principle” [BIOCHIMIE 178C (2020) 39–48]	6
On the footsteps of Hippocrates, Sanctorius and Harvey to better understand the influence of cold on the occurrence of COVID-19 in European countries in 2020	6
Evaluation of the effect of dimethyl fumarate on human bone marrow-derived mesenchymal stem cells using bottom-up proteomics	6
Melatonin as an adjuvant treatment modality with doxorubicin [Biochimie 200 (2022) 1–7]	6
Adipokines from white adipose tissue in regulation of whole body energy homeostasis	6
Reporter system controlled by the involucrin promoter as a tool to follow epidermal differentiation	6
Biochemical and metabolic characterization of a G6PC2 inhibitor	6
High-salt diet induces dyslipidemia through the SREBP2/PCSK9 pathway in dahl salt-sensitive rats	6
Biochemical aspects of hemoglobin-xenobiotic interactions and their implications in drug discovery	6
The multifaceted role of proteases and modern analytical methods for investigation of their catalytic activity	6
Inside front cover-EDB	6
Probing G-quadruplex-ligand binding using DNA intrinsic fluorescence	6
Structure determination and analyses of the GAPDH from the parasite Schistosoma mansoni, the first one from a platyhelminth	6
Proteomic and toxicological characterization of the venoms of the most enigmatic group of rattlesnakes: The long-tailed rattlesnakes	6
Novel chimeric peptides based on endomorphins and ghrelin receptor antagonist produced supraspinal antinociceptive effects with reduced acute tolerance in mice	6
Mitochondrial proteases modulate mitochondrial stress signalling and cellular homeostasis in health and disease	6
Exploring NAD+ metabolism and NNAT: Insights from structure, function, and computational modeling	6
“Humanizing” mouse environments: Humidity, diurnal cycles and thermoneutrality	6
Lethal action of Licarin A derivatives in Leishmania (L.) infantum: Imbalance of calcium and bioenergetic metabolism	6
IGFBP6 regulates extracellular vesicles formation via cholesterol abundance in MDA-MB-231 cells	6
Novel quaternary structures of the human prion protein globular domain	6
Polyamines putrescine and spermidine as modulators of protein aggregation rate: The effect on DTT-induced aggregation of α-lactalbumin	6
CRISPR/Cas9-mediated knock-out of AGXT1 in HepG2 cells as a new in vitro model of Primary Hyperoxaluria Type 1	6
Sialic acid-containing glycans play a role in the activity of snake venom proteases	6
The mutual and dynamic role of TSPO and ligands in their binding process: An example with PK-11195	6
Identification of an acetyl esterase in the supernatant of the environmental strain Bacillus sp. HR21-6	6
Ubash3b promotes TPA-mediated suppression of leukemogenesis through accelerated downregulation of PKCδ protein	6
In vitro and in vivo evidence of the antineoplastic activity of quercetin against endothelial cells transformed by Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor	6
The pentose phosphate pathway (PPP) in the glioma metabolism: A potent enhancer of malignancy	6
Unravelling the molecular interactions between the SARS-CoV-2 RBD spike protein and various specific monoclonal antibodies	6
CRISPR/Cas9-mediated epigenetic editing tool: An optimized strategy for targeting de novo DNA methylation with stable status via homology directed repair pathway	6
Unlocking the enigma of phenotypic drug tolerance: Mechanisms and emerging therapeutic strategies	5
Retinoic acid restores the levels of cellular cholesterol in Leishmania donovani infected macrophages by increasing npc1 and npc2 expressions	5
Unveiling the mechanism of hesperidin-induced LdTopI-mediated cell death pathway in protozoan parasite Leishmania donovani	5
Antimicrobial nano-assemblies of tryptocidine C, a tryptophan-rich cyclic decapeptide, from ethanolic solutions	5