Biochimie

Papers
(The median citation count of Biochimie is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2211
The key role of Warburg effect in SARS-CoV-2 replication and associated inflammatory response103
Role of AMPK mediated pathways in autophagy and aging101
May omega-3 fatty acid dietary supplementation help reduce severe complications in Covid-19 patients?98
Eicosapentaenoic and docosahexaenoic acid derived specialised pro-resolving mediators: Concentrations in humans and the effects of age, sex, disease and increased omega-3 fatty acid intake93
Current perspectives for microbial lipases from extremophiles and metagenomics77
Human health benefits of very-long-chain polyunsaturated fatty acids from microalgae68
In silico molecular docking in DNA aptamer development67
Vimentin: Regulation and pathogenesis60
Reactive oxygen and nitrogen species and innate immune response56
Molecular docking simulation reveals ACE2 polymorphisms that may increase the affinity of ACE2 with the SARS-CoV-2 Spike protein55
Jejunum: The understudied meeting place of dietary lipids and the microbiota48
Stroke treatment: Is exosome therapy superior to stem cell therapy?44
Brown/Beige adipose tissues and the emerging role of their secretory factors in improving metabolic health: The batokines39
Biochemical properties, nutritional values, health benefits and sustainability of palm oil38
Treatments in Covid-19 patients with pre-existing metabolic dysfunction-associated fatty liver disease: A potential threat for drug-induced liver injury?38
Role of Nrf2 and mitochondria in cancer stem cells; in carcinogenesis, tumor progression, and chemoresistance37
Fundamental insights into the interaction between telomerase/TERT and intracellular signaling pathways36
Inhibition of interleukin-2-inducible T-cell kinase causes reduction in imiquimod-induced psoriasiform inflammation through reduction of Th17 cells and enhancement of Treg cells in mice36
Analyses of viral genomes for G-quadruplex forming sequences reveal their correlation with the type of infection35
Mesenchymal stem cells: Biological characteristics and application in disease therapy35
Role of tryptophan metabolism in cancers and therapeutic implications34
BAP31: Physiological functions and roles in disease34
Role of pyroptosis in cancer cells and clinical applications34
Therapeutic applications of mitochondrial transplantation33
Functional effects of protein variants33
The neuroprotective and antidiabetic effects of trigonelline: A review of signaling pathways and molecular mechanisms31
Diabetes mellitus and melatonin: Where are we?30
DNA cleavage mechanism by metal complexes of Cu(II), Zn(II) and VO(IV) with a schiff-base ligand29
Brucein D modulates MAPK signaling cascade to exert multi-faceted anti-neoplastic actions against breast cancer cells29
A regulatory role of circRNA-miRNA-mRNA network in osteoblast differentiation28
Natural and synthetic retinoid X receptor ligands and their role in selected nuclear receptor action28
Advances in characterization of SIRT3 deacetylation targets in mitochondrial function28
Bis(monoacylglycero)phosphate, a new lipid signature of endosome-derived extracellular vesicles27
LncRNA ZFAS1 inhibits triple-negative breast cancer by targeting STAT327
Odd-chain fatty acids as novel histone deacetylase 6 (HDAC6) inhibitors27
Biotechnology tools and applications for development of oilseed crops with healthy vegetable oils27
Adipokines from white adipose tissue in regulation of whole body energy homeostasis26
Wnt/β-catenin signaling in colorectal cancer: Is therapeutic targeting even possible?26
Membrane heist: Coronavirus host membrane remodeling during replication26
PCR enhancers: Types, mechanisms, and applications in long-range PCR26
Osteoporosis: A role for lipids26
High prevalence for obesity in severe COVID-19: Possible links and perspectives towards patient stratification25
The chemical composition and lipid profile of the chub mackerel (Scomber colias) show a strong seasonal dependence: Contribution to a nutritional evaluation25
Curcumin analogs exhibit anti-cancer activity by selectively targeting G-quadruplex forming c-myc promoter sequence24
Cellular binding and uptake of fluorescent glucose analogs 2-NBDG and 6-NBDG occurs independent of membrane glucose transporters24
Research mechanisms of and pharmaceutical treatments for ferroptosis in liver diseases24
Bis(monoacylglycero)phosphate, an important actor in the host endocytic machinery hijacked by SARS-CoV-2 and related viruses23
The impact of endocrine disrupting compounds and carcinogens in wastewater: Implications for breast cancer23
Y box binding protein 1 (YB-1) oncoprotein at the hub of DNA proliferation, damage and cancer progression23
Wnt/β-catenin signaling pathway-a versatile player in apoptosis and autophagy23
KDM6B (JMJD3) and its dual role in cancer22
Essential sufficiency of zinc, ω-3 polyunsaturated fatty acids, vitamin D and magnesium for prevention and treatment of COVID-19, diabetes, cardiovascular diseases, lung diseases and cancer22
Na/K-ATPase: Their role in cell adhesion and migration in cancer22
The endosomal lipid bis(monoacylglycero) phosphate as a potential key player in the mechanism of action of chloroquine against SARS-COV-2 and other enveloped viruses hijacking the endocytic pathway22
Bacillus thuringiensis: From biopesticides to anticancer agents21
Plant lectin: A promising future anti-tumor drug21
Shaping the gut microbiota by bioactive phytochemicals: An emerging approach for the prevention and treatment of human diseases21
A novel anionic cathelicidin lacking direct antimicrobial activity but with potent anti-inflammatory and wound healing activities from the salamander Tylototriton kweichowensis21
Dbr1 functions in mRNA processing, intron turnover and human diseases19
Design and characterization of new antimicrobial peptides derived from aurein 1.2 with enhanced antibacterial activity19
The chemical mechanisms of the enzymes in the branched-chain amino acids biosynthetic pathway and their applications19
Beyond amyloid proteins: Thioflavin T in nucleic acid recognition19
Adipokines in obesity and metabolic-related-diseases19
Possible cancer-causing capacity of COVID-19: Is SARS-CoV-2 an oncogenic agent?19
Nuclear transformation of Chlamydomonas reinhardtii: A review19
Oxidative distress in aging and age-related diseases: Spatiotemporal dysregulation of protein oxidation and degradation19
Roles of microRNAs in carbohydrate and lipid metabolism disorders and their therapeutic potential18
HIV-1 Tat: An update on transcriptional and non-transcriptional functions18
Plasmodium’s journey through the Anopheles mosquito: A comprehensive review18
Inborn errors in the vitamin B6 salvage enzymes associated with neonatal epileptic encephalopathy and other pathologies17
Prolidase – A protein with many faces17
Proteomics analysis of Cyclobalanopsis gilva provides new insights of low seed germination17
EGCG as an anti-SARS-CoV-2 agent: Preventive versus therapeutic potential against original and mutant virus17
Discovery of a multi-target compound for estrogen receptor-positive (ER+) breast cancer: Involvement of aromatase and ERs17
Involvement of aquaglyceroporins in energy metabolism in health and disease17
Loss of WD2 subdomain of Apaf-1 forms an apoptosome structure which blocks activation of caspase-3 and caspase-917
Sulfur amino acid metabolism and related metabotypes of autism spectrum disorder: A review of biochemical evidence for a hypothesis17
Breast cancer organoid model allowed to reveal potentially beneficial combinations of 3,3′-diindolylmethane and chemotherapy drugs17
Extracellular vesicles of MSCs and cardiomyoblasts are vehicles for lipid mediators16
Pancreatic islet cells disarray, apoptosis, and proliferation in obese mice. The role of Semaglutide treatment16
Contribution of Apaf-1 to the pathogenesis of cancer and neurodegenerative diseases16
ConBr lectin modulates MAPKs and Akt pathways and triggers autophagic glioma cell death by a mechanism dependent upon caspase-8 activation16
Biomembrane lipids: When physics and chemistry join to shape biological activity16
Single and consecutive application of near-infrared and green irradiation modulates adipose derived stem cell proliferation and affect differentiation factors16
Stability and context of intercalated motifs (i-motifs) for biological applications16
Cellular and molecular modification of egg envelope hardening in fertilization15
Novel G-quadruplex prone sequences emerge in the complete assembly of the human X chromosome15
Naturally occurring cobalamin (B12) analogs can function as cofactors for human methylmalonyl-CoA mutase15
Role of mitochondrial calcium in hypochlorite induced oxidative damage of cells15
Characterization and modulation of brain lipids content of rainbow trout fed with 100% plant based diet rich in omega-3 long chain polyunsaturated fatty acids DHA and EPA15
Tanshinone IIA exerts autophagic cell death through down-regulation of β-catenin in renal cell carcinoma cells15
Cancer diets for cancer patients: Lessons from mouse studies and new insights from the study of fatty acid metabolism in tumors15
Decreased cortical Nrf2 gene expression in autism and its relationship to thiol and cobalamin status15
Oncostatic activities of melatonin: Roles in cell cycle, apoptosis, and autophagy15
trans-Anethole attenuated renal injury and reduced expressions of angiotensin II receptor (AT1R) and TGF-β in streptozotocin-induced diabetic rats15
Allosteric transitions of rabbit skeletal muscle lactate dehydrogenase induced by pH-dependent dissociation of the tetrameric enzyme15
G-quadruplex motifs are functionally conserved in cis-regulatory regions of pathogenic bacteria: An in-silico evaluation15
Early shedding of membrane-bounded ACE2 could be an indicator for disease severity in SARS-CoV-214
Regulation of mitochondrial function by forkhead transcription factors14
Versatility of mesenchymal stem cell-derived extracellular vesicles in tissue repair and regenerative applications14
EPHA2 antisense RNA modulates EPHA2 mRNA levels in basal-like/triple-negative breast cancer cells14
Molecular simulation studies of the interactions between the human/pangolin/cat/bat ACE2 and the receptor binding domain of the SARS-CoV-2 spike protein14
Adipose-derived stem/stromal cell secretome modulates breast cancer cell proliferation and differentiation state towards aggressiveness14
The diversity of lipocalin receptors14
α-Conotoxin RgIA and oligoarginine R8 in the mice model alleviate long-term oxaliplatin induced neuropathy14
The role of G-Quadruplex DNA in Paraspeckle formation in cancer14
Lipidomic analysis of human corneal epithelial cells exposed to ocular irritants highlights the role of phospholipid and sphingolipid metabolisms in detergent toxicity mechanisms14
The effect of electrospun scaffolds on the glycosaminoglycan profile of differentiating neural stem cells14
Intestinal interplay of quorum sensing molecules and human receptors14
Exosomal lipids from membrane organization to biomarkers: Focus on an endolysosomal-specific lipid13
Non-B DNA structures as a booster of genome instability13
High salt diet contributes to hypertension by weakening the medullary tricarboxylic acid cycle and antioxidant system in Dahl salt-sensitive rats13
Histone code reader SPIN1 is a promising target of cancer therapy13
Up-regulation of PCSK6 by lipid oxidation products: A possible role in atherosclerosis13
Serotonergic drugs modulate the phase behavior of complex lipid bilayers12
Oleochemistry potential from Brazil northeastern exotic plants12
Human sperm functioning is related to the aquaporin-mediated water and hydrogen peroxide transport regulation12
The structural and molecular biology of type IV galactosemia12
Stabilization of a DNA aptamer by ligand binding12
Production, characteristics and applications of microbial heparinases12
Structural and functional impact of clinically relevant E1α variants causing pyruvate dehydrogenase complex deficiency12
Inhibition of LPAR6 overcomes sorafenib resistance by switching glycolysis into oxidative phosphorylation in hepatocellular carcinoma12
Levalbuterol lowers the feedback inhibition by dopamine and delays misfolding and aggregation in tyrosine hydroxylase12
Biochemical aspects of hemoglobin-xenobiotic interactions and their implications in drug discovery12
The role of melatonin in bone regeneration: A review of involved signaling pathways12
Coronaviruses, cholesterol and statins: Involvement and application for Covid-1912
Mitochondrial peptide Mtln contributes to oxidative metabolism in mice11
Relaxin in hepatic fibrosis: What is known and where to head?11
Oncostatic activities of melatonin: Roles in cell cycle, apoptosis, and autophagy [Biochimie 200 (2022) 44–59]11
Mig6 not only inhibits EGFR and HER2 but also targets HER3 and HER4 in a differential specificity: Implications for targeted esophageal cancer therapy11
Free advanced glycation end product distribution in blood components and the effect of genetic polymorphisms11
Tau R2 and R3 are essential regions for tau aggregation, seeding and propagation11
Musculoskeletal regeneration: A zebrafish perspective11
Structure and activation mechanism of the human liver-type glutaminase GLS211
Novel activity of human BChE: Lipid hydrolysis11
Regulation of apoptosis and autophagy by albendazole in human colon adenocarcinoma cells11
Zinc binding loop mutations of hSOD1 promote amyloid fibrils under physiological conditions: Implications for initiation of amyotrophic lateral sclerosis11
Aquaporins with lactate/lactic acid permeability at physiological pH conditions11
A two-quartet G-quadruplex topology of human KIT2 is conformationally selected by a perylene derivative11
Evaluating the role of nitric oxide in myogenesis in vitro11
Skatole: A thin red line between its benefits and toxicity11
Heteroarene-fused anthraquinone derivatives as potential modulators for human aurora kinase B11
The stimulation of succinate-fueled respiration of rat liver mitochondria in state 4 by α,ω-hexadecanedioic acid without induction of proton conductivity of the inner membrane. Intrinsic uncoupling of11
Protein structural heterogeneity: A hypothesis for the basis of proteolytic recognition by the main protease of SARS-CoV and SARS-CoV-211
A regenerative approach to the pharmacological management of hard-to-heal wounds11
Pigment epithelium-derived factor and its role in microvascular-related diseases10
Transcriptional regulation of alcohol induced liver fibrosis in a translational porcine hepatocellular carcinoma model10
The enzymes in COVID-19: A review10
Structural considerations on lipoxygenase function, inhibition and crosstalk with nitric oxide pathways10
Metal effect on intein splicing: A review10
Experimental models of lipid overload and their relevance in understanding skeletal muscle insulin resistance and pathological changes in mitochondrial oxidative capacity10
Potential physio-pathological effects of branched fatty acid esters of hydroxy fatty acids10
Functional roles of human Up-frameshift suppressor 3 (UPF3) proteins: From nonsense-mediated mRNA decay to neurodevelopmental disorders10
Anti-inflammatory and anti-virus potential of poxytrins, especially protectin DX10
TRPP2 ion channels: The roles in various subcellular locations10
Fatty acid binding protein 7 mediates linoleic acid-induced cell death in triple negative breast cancer cells by modulating 13-HODE10
Intraspecific venom variation of Mexican West Coast Rattlesnakes (Crotalus basiliscus) and its implications for antivenom production10
Structural and thermodynamic analyses of human TMED1 (p24γ1) Golgi dynamics10
Conservation and over-representation of G-quadruplex sequences in regulatory regions of mitochondrial DNA across distinct taxonomic sub-groups10
Succinyl-CoA:3-oxoacid coenzyme A transferase (SCOT) deficiency: A rare and potentially fatal metabolic disease10
Guidelines for G-quadruplexes: I. In vitro characterization10
Biochemical, pharmacological and structural characterization of BmooMP-I, a new P–I metalloproteinase from Bothrops moojeni venom10
Skin aquaporins as druggable targets: Promoting health by addressing the disease10
Glucose deprivation using 2-deoxyglucose and acarbose induce metabolic oxidative stress and apoptosis in female mice bearing breast cancer10
Molecular and cellular mechanisms of melatonin in breast cancer10
Imbalance between alpha-1-antitrypsin and interleukin 6 is associated with in-hospital mortality and thrombosis during COVID-199
CRISPR/Cas gene-editing technology and its advances in dentistry9
Exosomes derived from mesenchymal stem cells: A promising cell-free therapeutic tool for cutaneous wound healing9
Heart and kidney H2S production is reduced in hypertensive and older rats9
Elucidating carbohydrate metabolism in Euglena gracilis: Reverse genetics-based evaluation of genes coding for enzymes linked to paramylon accumulation9
AICAR stimulates mitochondrial biogenesis and BCAA catabolic enzyme expression in C2C12 myotubes9
Phylogenetics and biochemistry elucidate the evolutionary link between l-malate and l-lactate dehydrogenases and disclose an intermediate group of sequences with mix functional properties9
Mutations in the coordination spheres of T1 Cu affect Cu2+-activation of the laccase from Thermus thermophilus9
Retinoic acid restores the levels of cellular cholesterol in Leishmania donovani infected macrophages by increasing npc1 and npc2 expressions9
Binding of SARS-CoV-2 protein ORF9b to mitochondrial translocase TOM70 prevents its interaction with chaperone HSP909
Melatonin and inflammatory bowel disease: From basic mechanisms to clinical application9
Identification of small molecule allosteric modulators of 5,10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain9
Rescue effect of sodium acetate in diabetes mellitus-associated testicular dysfunction is accompanied by PCSK9 modulation9
Thiolatocobalamins repair the activity of pathogenic variants of the human cobalamin processing enzyme CblC9
Shift in phospholipid and fatty acid contents accompanies brain myelination9
Humanizing plant-derived snakins and their encrypted antimicrobial peptides9
Aquaporins implicated in the cell proliferation and the signaling pathways of cell stemness9
Phospholipase A2, a nonnegligible enzyme superfamily in gastrointestinal diseases9
Travel light: Essential packing for membrane proteins with an active lifestyle8
Cancer stem cell-derived exosome-induced metastatic cancer: An orchestra within the tumor microenvironment8
Lactic acid fermentation: A maladaptive mechanism and an evolutionary throwback boosting cancer drug resistance8
NMS-873 functions as a dual inhibitor of mitochondrial oxidative phosphorylation8
Lactose-binding lectin from Vatairea macrocarpa seeds induces in vivo angiogenesis via VEGF and TNF-ɑ expression and modulates in vitro doxorubicin-induced genotoxicity8
Cytotoxic effects of aptamer-doxorubicin conjugates in an ovarian cancer cell line8
Muscles proteome analysis; irisin administration mimics some molecular effects of exercise in quadriceps muscle8
Anticancer activity of D-LAK-120A, an antimicrobial peptide, in non-small cell lung cancer (NSCLC)8
Crystal structure of Dictyoglomus thermophilum β-d-xylosidase DtXyl unravels the structural determinants for efficient notoginsenoside R1 hydrolysis8
Fractionating stem cells secretome for Parkinson's disease modeling: Is it the whole better than the sum of its parts?8
Functions of long non-coding RNA ROR in patient-derived glioblastoma cells8
Daidzein-directed methionine γ-lyase in enzyme prodrug therapy against breast cancer8
DHEA-pretreatment attenuates oxidative stress in kidney-cortex and liver of diabetic rabbits and delays development of the disease8
X-aptamers targeting Thy-1 membrane glycoprotein in pancreatic ductal adenocarcinoma8
3-aminobenzamide protects against colitis associated diabetes mellitus in male BALB/c mice: Role of PARP-1, NLRP3, SIRT-1, AMPK8
Recent progress in leptin signaling from a structural perspective and its implications for diseases8
Grapevine aquaporins: Diversity, cellular functions, and ecophysiological perspectives8
Neuroprotective effect of 6-hydroxy-2,2,4-trimethyl-1,2-dihydroquinoline mediated via regulation of antioxidant system and inhibition of inflammation and apoptosis in a rat model of cerebral ischemia/8
Hematopoietically-expressed homeobox protein HHEX regulates adipogenesis in preadipocytes8
In-solution structural studies involving a phospholipase A2-like myotoxin and a natural inhibitor: Plasticity of oligomeric assembly affects mechanisms of inhibition8
What do secreted phospholipases A2 have to offer in combat against different viruses up to SARS-CoV-2?8
What happens when the mitochondrial H+-translocating F1FO-ATP(hydrol)ase becomes a molecular target of calcium? The pore opens8
Biological evaluation and spectral characterization of a novel tetracenomycin X congener8
The hide-and-seek game of the oncogenic Epstein-Barr virus-encoded EBNA1 protein with the immune system: An RNA G-quadruplex tale7
p53 knock-down and hypoxia affects glutathione peroxidase 4 antioxidant response in hepatopancreas of the white shrimp Litopenaeus vannamei7
CD151 enrichment in exosomes of luminal androgen receptor breast cancer cell line contributes to cell invasion7
Neurotoxic or neuroprotective: Post-translational modifications of α-synuclein at the cross-roads of functions7
Cassava (Manihot esculenta) defensins: Prospection, structural analysis and tissue-specific expression under biotic/abiotic stresses7
The role of Cannabidiol and tetrahydrocannabivarin to overcome doxorubicin resistance in MDA-MB-231 xenografts in athymic nude mice7
Multimodal plasma metabolomics and lipidomics in elucidating metabolic perturbations in tuberculosis patients with concurrent type 2 diabetes7
Recent advances in the use of legume lectins for the diagnosis and treatment of breast cancer7
The potential of antifungal peptide Sesquin as natural food preservative7
Molecular basis of melatonin protective effects in metastasis: A novel target of melatonin7
Impact of protein dynamics on secondary structure prediction7
SNAIL Transctiption factor in prostate cancer cells promotes neurite outgrowth7
Crystal structure of SFPQ-NONO heterodimer7
Frequent sequence variants of human glycine N-acyltransferase (GLYAT) and inborn errors of metabolism7
LEAP2 is a more conserved ligand than ghrelin for fish GHSRs7
Unveiling the biodiversity of lipid species in Corynebacteria- characterization of the uncommon lipid families in C. glutamicum and pathogen C. striatum by mass spectrometry7
Dynamics prediction of emerging notable spike protein mutations in SARS-CoV-2 implies a need for updated vaccines7
Site-directed mutations reflecting functional and structural properties of Ec-NhaA7
Mechanistic physicochemical insights into glycation and drug binding by serum albumin: Implications in diabetic conditions7
The digestion of diacylglycerol isomers by gastric and pancreatic lipases and its impact on the metabolic pathways for TAG re-synthesis in enterocytes7
The biochemical association between R157H mutation in human αB-crystallin and development of cardiomyopathy: Structural and functional analyses of the mutant protein7
Delta or Omega? Δ12 (ω6) fatty acid desaturases count 3C after the pre-existing double bond7
Structural basis of the myotoxic inhibition of the Bothrops pirajai PrTX-I by the synthetic varespladib7
Glutathione is required for growth and cadmium tolerance in the amphibian chytrid fungus, Batrachochytrium dendrobatidis7
Gene cluster from plant to microbes: Their role in genome architecture, organism's development, specialized metabolism and drug discovery7
Following tyrothricin peptide production by Brevibacillus parabrevis with electrospray mass spectrometry7
The NRSF/REST transcription factor in hallmarks of cancer: From molecular mechanisms to clinical relevance7
Analysis of the mechanisms of action of isopentenyl caffeate against Leishmania7
CRISPR/Cas9-mediated knock-out of AGXT1 in HepG2 cells as a new in vitro model of Primary Hyperoxaluria Type 17
The protein-bound uremic toxin p-cresyl-sulfate promotes intracellular ROS production and lipid peroxidation in 3T3-L1 adipose cells6
Role of SIRT5 in cancer. Friend or Foe?6
Housing temperature plays a critical role in determining gut microbiome composition in research mice: Implications for experimental reproducibility6
Effects of natural polymorphisms in SARS-CoV-2 RNA-dependent RNA polymerase on its activity and sensitivity to inhibitors in vitro6
Viral nanoparticles: Current advances in design and development6
Cancer and Trypanosoma cruzi: Tumor induction or protection?6
Effects of resveratrol on inflammation and oxidative stress induced by the uremic toxin indoxyl sulfate in Murine macrophage-like RAW 264.76
Molecular insights into the mechanism of substrate binding and catalysis of bifunctional FAD synthetase from Staphylococcus aureus6
Human transcriptional gene regulatory network compiled from 14 data resources6
Enzyme dysfunction at atomic resolution: Disease-associated variants of human phosphoglucomutase-16
Implication of cation-proton antiporters (CPA) in human health and diseases causing microorganisms6
A-family anti-inflammatory cyclopentenone prostaglandins: A novel class of non-statin inhibitors of HMG-CoA reductase6
Role of human group IIA secreted phospholipase A2 in malaria pathophysiology: Insights from a transgenic mouse model6
Functional analysis of Lsm protein under multiple stress conditions in the extreme haloarchaeon Haloferax mediterranei6
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