OOIR: Observatory of International Research

Papers

(The TQCC of Basic Research in Cardiology is 25. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 500 papers]. The publications cover those that have been published in the past four years, i.e., from 2019-09-01 to 2023-09-01.)

Article	Citations
Coronary microvascular obstruction: the new frontier in cardioprotection	152
COVID-19 in the heart and the lungs: could we “Notch” the inflammatory storm?	149
M1-like macrophage-derived exosomes suppress angiogenesis and exacerbate cardiac dysfunction in a myocardial infarction microenvironment	112
DNA-PKcs promotes cardiac ischemia reperfusion injury through mitigating BI-1-governed mitochondrial homeostasis	90
Microvascular and lymphatic dysfunction in HFpEF and its associated comorbidities	69
Mitochondrial noncoding RNA-regulatory network in cardiovascular disease	63
Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cere	61
Increased RyR2 activity is exacerbated by calcium leak-induced mitochondrial ROS	59
Acute exposure to nocturnal train noise induces endothelial dysfunction and pro-thromboinflammatory changes of the plasma proteome in healthy subjects	56
Reduced reticulum–mitochondria Ca2+ transfer is an early and reversible trigger of mitochondrial dysfunctions in diabetic cardiomyopathy	56
IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria: guidelines of the EU-CARDIOPROTECTION COST Action	55
TRPV4 deletion protects heart from myocardial infarction-induced adverse remodeling via modulation of cardiac fibroblast differentiation	55
Resolving the intertwining of inflammation and fibrosis in human heart failure at single-cell level	53
Vascular autophagy in health and disease	50
Perspective: cardiovascular disease and the Covid-19 pandemic	49
CARD9 promotes autophagy in cardiomyocytes in myocardial ischemia/reperfusion injury via interacting with Rubicon directly	49
Small extracellular vesicles secreted from human amniotic fluid mesenchymal stromal cells possess cardioprotective and promigratory potential	48
Enhancement of cardiac lymphangiogenesis by transplantation of CD34+VEGFR-3+ endothelial progenitor cells and sustained release of VEGF-C	46
PCSK9 regulates pyroptosis via mtDNA damage in chronic myocardial ischemia	46
Non-coding RNAs: emerging players in cardiomyocyte proliferation and cardiac regeneration	44
Mitochondrial connexin 43 in sex-dependent myocardial responses and estrogen-mediated cardiac protection following acute ischemia/reperfusion injury	42
Thrombin receptor PAR4 drives canonical NLRP3 inflammasome signaling in the heart	42
Allogeneic cardiosphere-derived cells (CAP-1002) in critically ill COVID-19 patients: compassionate-use case series	41
Cytokines as therapeutic targets for cardio- and cerebrovascular diseases	39
Selective intrarenal delivery of mesenchymal stem cell-derived extracellular vesicles attenuates myocardial injury in experimental metabolic renovascular disease	39

Exercise improves cardiac function and glucose metabolism in mice with experimental myocardial infarction through inhibiting HDAC4 and upregulating GLUT1 expression	38
Cellular and mitochondrial mechanisms of atrial fibrillation	38
Does remote ischaemic conditioning reduce inflammation? A focus on innate immunity and cytokine response	37
Neuraminidase-1 promotes heart failure after ischemia/reperfusion injury by affecting cardiomyocytes and invading monocytes/macrophages	36
Mouse models of atherosclerosis and their suitability for the study of myocardial infarction	34
Hyperglycemia regulates cardiac K+ channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways	33
Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering	33
Inflammation shapes pathogenesis of murine arrhythmogenic cardiomyopathy	33
Fibroblast growth factor 21 inhibited ischemic arrhythmias via targeting miR-143/EGR1 axis	32
NAD+ administration decreases microvascular damage following cardiac ischemia/reperfusion by restoring autophagic flux	32
Anaemia is associated with severe RBC dysfunction and a reduced circulating NO pool: vascular and cardiac eNOS are crucial for the adaptation to anaemia	31
Triad3A attenuates pathological cardiac hypertrophy involving the augmentation of ubiquitination-mediated degradation of TLR4 and TLR9	30
Nuclear localization of a novel calpain-2 mediated junctophilin-2 C-terminal cleavage peptide promotes cardiomyocyte remodeling	30
Regulation of STAT3 and its role in cardioprotection by conditioning: focus on non-genomic roles targeting mitochondrial function	30
Remote ischemic preconditioning reduces myocardial ischemia–reperfusion injury through unacylated ghrelin-induced activation of the JAK/STAT pathway	29
Perturbations in myocardial perfusion and oxygen balance in swine with multiple risk factors: a novel model of ischemia and no obstructive coronary artery disease	29
Metoprolol blunts the time-dependent progression of infarct size	29
Coronary blood flow in heart failure: cause, consequence and bystander	29
Fibroblast GATA-4 and GATA-6 promote myocardial adaptation to pressure overload by enhancing cardiac angiogenesis	29
Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants	28
Glucagon-like peptide-1 (GLP-1) receptor activation dilates cerebral arterioles, increases cerebral blood flow, and mediates remote (pre)conditioning neuroprotection against ischaemic stroke	28
Cardiomyocyte Na+ and Ca2+ mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors	27
Inhibition of NaV1.8 prevents atrial arrhythmogenesis in human and mice	27
Plasminogen activator inhibitor-1 reduces cardiac fibrosis and promotes M2 macrophage polarization in inflammatory cardiomyopathy	27
Protective effect of HINT2 on mitochondrial function via repressing MCU complex activation attenuates cardiac microvascular ischemia–reperfusion injury	26
A future for remote ischaemic conditioning in high-risk patients	26
Targeting myocardial ischaemic injury in the absence of reperfusion	26
Overexpression of mitochondrial creatine kinase preserves cardiac energetics without ameliorating murine chronic heart failure	25
Interruption of vascular endothelial growth factor receptor 2 signaling induces a proliferative pulmonary vasculopathy and pulmonary hypertension	25
Cardioprotection by remote ischemic conditioning is transferable by plasma and mediated by extracellular vesicles	25
miR-106a–363 cluster in extracellular vesicles promotes endogenous myocardial repair via Notch3 pathway in ischemic heart injury	25