Basic Research in Cardiology

(The TQCC of Basic Research in Cardiology is 26. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
Resolving the intertwining of inflammation and fibrosis in human heart failure at single-cell level90
Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cere81
Microvascular and lymphatic dysfunction in HFpEF and its associated comorbidities77
IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria: guidelines of the EU-CARDIOPROTECTION COST Action73
Reduced reticulum–mitochondria Ca2+ transfer is an early and reversible trigger of mitochondrial dysfunctions in diabetic cardiomyopathy73
Increased RyR2 activity is exacerbated by calcium leak-induced mitochondrial ROS72
Cellular and mitochondrial mechanisms of atrial fibrillation65
PCSK9 regulates pyroptosis via mtDNA damage in chronic myocardial ischemia57
Vascular autophagy in health and disease55
Non-coding RNAs: emerging players in cardiomyocyte proliferation and cardiac regeneration52
Cytokines as therapeutic targets for cardio- and cerebrovascular diseases51
Coronary blood flow in heart failure: cause, consequence and bystander49
Mouse models of atherosclerosis and their suitability for the study of myocardial infarction49
Hyperglycemia regulates cardiac K+ channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways45
Protective effect of HINT2 on mitochondrial function via repressing MCU complex activation attenuates cardiac microvascular ischemia–reperfusion injury44
Allogeneic cardiosphere-derived cells (CAP-1002) in critically ill COVID-19 patients: compassionate-use case series42
Mitochondrial calpain-1 activates NLRP3 inflammasome by cleaving ATP5A1 and inducing mitochondrial ROS in CVB3-induced myocarditis42
Does remote ischaemic conditioning reduce inflammation? A focus on innate immunity and cytokine response41
Neuraminidase-1 promotes heart failure after ischemia/reperfusion injury by affecting cardiomyocytes and invading monocytes/macrophages40
Regulation of STAT3 and its role in cardioprotection by conditioning: focus on non-genomic roles targeting mitochondrial function39
Inflammation shapes pathogenesis of murine arrhythmogenic cardiomyopathy39
Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering38
NAD+ administration decreases microvascular damage following cardiac ischemia/reperfusion by restoring autophagic flux37
Remote ischemic preconditioning reduces myocardial ischemia–reperfusion injury through unacylated ghrelin-induced activation of the JAK/STAT pathway36
Plasminogen activator inhibitor-1 reduces cardiac fibrosis and promotes M2 macrophage polarization in inflammatory cardiomyopathy35
Anaemia is associated with severe RBC dysfunction and a reduced circulating NO pool: vascular and cardiac eNOS are crucial for the adaptation to anaemia35
Nuclear localization of a novel calpain-2 mediated junctophilin-2 C-terminal cleavage peptide promotes cardiomyocyte remodeling35
Cardiomyocyte Na+ and Ca2+ mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors34
Fibroblast GATA-4 and GATA-6 promote myocardial adaptation to pressure overload by enhancing cardiac angiogenesis34
miR-106a–363 cluster in extracellular vesicles promotes endogenous myocardial repair via Notch3 pathway in ischemic heart injury33
Glucagon-like peptide-1 (GLP-1) receptor activation dilates cerebral arterioles, increases cerebral blood flow, and mediates remote (pre)conditioning neuroprotection against ischaemic stroke33
Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants32
Targeting myocardial ischaemic injury in the absence of reperfusion32
Metoprolol blunts the time-dependent progression of infarct size31
Cardioprotection by remote ischemic conditioning is transferable by plasma and mediated by extracellular vesicles30
Blunting TRPML1 channels protects myocardial ischemia/reperfusion injury by restoring impaired cardiomyocyte autophagy30
Resident cardiac macrophages: crucial modulators of cardiac (patho)physiology30
Adenosine and adenosine receptor-mediated action in coronary microcirculation28
Functional investigation of the coronary artery disease gene SVEP127
LncRNA LncHrt preserves cardiac metabolic homeostasis and heart function by modulating the LKB1-AMPK signaling pathway27
Selective NADH communication from α-ketoglutarate dehydrogenase to mitochondrial transhydrogenase prevents reactive oxygen species formation under reducing conditions in the heart27
SAIL: a new conserved anti-fibrotic lncRNA in the heart27
Interruption of vascular endothelial growth factor receptor 2 signaling induces a proliferative pulmonary vasculopathy and pulmonary hypertension26