OOIR: Observatory of International Research

Papers

(The median citation count of Basic Research in Cardiology is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Resolving the intertwining of inflammation and fibrosis in human heart failure at single-cell level	107
Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cere	96
Reduced reticulum–mitochondria Ca2+ transfer is an early and reversible trigger of mitochondrial dysfunctions in diabetic cardiomyopathy	86
IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria: guidelines of the EU-CARDIOPROTECTION COST Action	86
Cellular and mitochondrial mechanisms of atrial fibrillation	79
PCSK9 regulates pyroptosis via mtDNA damage in chronic myocardial ischemia	67
Coronary blood flow in heart failure: cause, consequence and bystander	61
Cytokines as therapeutic targets for cardio- and cerebrovascular diseases	58
Mitochondrial calpain-1 activates NLRP3 inflammasome by cleaving ATP5A1 and inducing mitochondrial ROS in CVB3-induced myocarditis	58
Mouse models of atherosclerosis and their suitability for the study of myocardial infarction	58
Protective effect of HINT2 on mitochondrial function via repressing MCU complex activation attenuates cardiac microvascular ischemia–reperfusion injury	54
Blunting TRPML1 channels protects myocardial ischemia/reperfusion injury by restoring impaired cardiomyocyte autophagy	48
Does remote ischaemic conditioning reduce inflammation? A focus on innate immunity and cytokine response	47
Hyperglycemia regulates cardiac K+ channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways	47
Regulation of STAT3 and its role in cardioprotection by conditioning: focus on non-genomic roles targeting mitochondrial function	46
Plasminogen activator inhibitor-1 reduces cardiac fibrosis and promotes M2 macrophage polarization in inflammatory cardiomyopathy	41
Cardiomyocyte Na+ and Ca2+ mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors	41
Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering	39
Fibroblast GATA-4 and GATA-6 promote myocardial adaptation to pressure overload by enhancing cardiac angiogenesis	38
miR-106a–363 cluster in extracellular vesicles promotes endogenous myocardial repair via Notch3 pathway in ischemic heart injury	37
Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants	37
Cardioprotection by selective SGLT-2 inhibitors in a non-diabetic mouse model of myocardial ischemia/reperfusion injury: a class or a drug effect?	37
Glucagon-like peptide-1 (GLP-1) receptor activation dilates cerebral arterioles, increases cerebral blood flow, and mediates remote (pre)conditioning neuroprotection against ischaemic stroke	36
Cardioprotection by remote ischemic conditioning is transferable by plasma and mediated by extracellular vesicles	36
Resident cardiac macrophages: crucial modulators of cardiac (patho)physiology	35

Adenosine and adenosine receptor-mediated action in coronary microcirculation	35
LncRNA LncHrt preserves cardiac metabolic homeostasis and heart function by modulating the LKB1-AMPK signaling pathway	31
Connexin 43 phosphorylation by casein kinase 1 is essential for the cardioprotection by ischemic preconditioning	30
Macrophage depletion in stellate ganglia alleviates cardiac sympathetic overactivation and ventricular arrhythmogenesis by attenuating neuroinflammation in heart failure	30
Regulatory B cells improve ventricular remodeling after myocardial infarction by modulating monocyte migration	29
SAIL: a new conserved anti-fibrotic lncRNA in the heart	29
Functional investigation of the coronary artery disease gene SVEP1	28
AMPKα1 deletion in myofibroblasts exacerbates post-myocardial infarction fibrosis by a connexin 43 mechanism	28
Thiol-based redox-active proteins as cardioprotective therapeutic agents in cardiovascular diseases	28
HIMF deletion ameliorates acute myocardial ischemic injury by promoting macrophage transformation to reparative subtype	27
Remote ischaemic conditioning: defining critical criteria for success—report from the 11th Hatter Cardiovascular Workshop	27
The zinc transporter ZIP7 (Slc39a7) controls myocardial reperfusion injury by regulating mitophagy	27
Transcriptome-wide association study of coronary artery disease identifies novel susceptibility genes	27
Reverse re-modelling chronic heart failure by reinstating heart rate variability	27
Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects	26
Metabolism regulator adiponectin prevents cardiac remodeling and ventricular arrhythmias via sympathetic modulation in a myocardial infarction model	25
SKI activates the Hippo pathway via LIMD1 to inhibit cardiac fibroblast activation	25
Vascular conditioning prevents adverse left ventricular remodelling after acute myocardial infarction: a randomised remote conditioning study	25
Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs	24
Effect of COMBinAtion therapy with remote ischemic conditioning and exenatide on the Myocardial Infarct size: a two-by-two factorial randomized trial (COMBAT-MI)	23
Regional analysis of inflammation and contractile function in reperfused acute myocardial infarction by in vivo 19F cardiovascular magnetic resonance in pigs	21
Non-responsiveness to cardioprotection by ischaemic preconditioning in Ossabaw minipigs with genetic predisposition to, but without the phenotype of the metabolic syndrome	21
Cardioprotection by post-conditioning with exogenous triiodothyronine in isolated perfused rat hearts and isolated adult rat cardiomyocytes	21
CaMKII and PKA-dependent phosphorylation co-regulate nuclear localization of HDAC4 in adult cardiomyocytes	21
Osteopontin promotes infarct repair	20
Distributed synthesis of sarcolemmal and sarcoplasmic reticulum membrane proteins in cardiac myocytes	20
Bone marrow-derived naïve B lymphocytes improve heart function after myocardial infarction: a novel cardioprotective mechanism for empagliflozin	20
Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1	20
Optogenetic manipulation of cardiac electrical dynamics using sub-threshold illumination: dissecting the role of cardiac alternans in terminating rapid rhythms	19
Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant	19
Single-cell transcriptomic identified HIF1A as a target for attenuating acute rejection after heart transplantation	19
The importance of clinically relevant background therapy in cardioprotective studies	19
Pathogenesis of arrhythmogenic cardiomyopathy: role of inflammation	18
Autocrine effects of PCSK9 on cardiomyocytes	18
Translation of experimental cardioprotective capability of P2Y12 inhibitors into clinical outcome in patients with ST-elevation myocardial infarction	17
Chronic isoprenaline/phenylephrine vs. exclusive isoprenaline stimulation in mice: critical contribution of alpha1-adrenoceptors to early cardiac stress responses	17
Loss of NPPA-AS1 promotes heart regeneration by stabilizing SFPQ–NONO heteromer-induced DNA repair	17
Nuclear Tkt promotes ischemic heart failure via the cleaved Parp1/Aif axis	17
Increased cytosolic calcium buffering contributes to a cellular arrhythmogenic substrate in iPSC-cardiomyocytes from patients with dilated cardiomyopathy	17
The miR-182/Myadm axis regulates hypoxia-induced pulmonary hypertension by balancing the BMP- and TGF-β-signalling pathways in an SMC/EC-crosstalk-associated manner	16
Omecamtiv mecarbil evokes diastolic dysfunction and leads to periodic electromechanical alternans	16
Clonal hematopoiesis and cardiovascular disease: deciphering interconnections	16
Characterizing the transition from immune response to tissue repair after myocardial infarction by multiparametric imaging	16
Innate immune cells in the pathophysiology of calcific aortic valve disease: lessons to be learned from atherosclerotic cardiovascular disease?	15
Mechanism of the switch from NO to H2O2 in endothelium-dependent vasodilation in diabetes	15
Why is endothelial resilience key to maintain cardiac health?	15
The platelet paradox of injury versus protection in myocardial infarction—has it been overlooked?	14
Neuronal guidance proteins in cardiovascular inflammation	14
Increased protein S-nitrosylation in mitochondria: a key mechanism of exercise-induced cardioprotection	14
CAESAR’s legacy: a new era of rigor in preclinical studies of cardioprotection	14

Endothelial ACKR3 drives atherosclerosis by promoting immune cell adhesion to vascular endothelium