OOIR: Observatory of International Research

Papers

(The TQCC of Connective Tissue Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Comparative characterization of hydrogels from human amniotic membrane and umbilical cord: biological and physicochemical properties	32
NEDD4L affects stability of the CHEK2/TP53 axis through ubiquitination modification to enhance osteogenic differentiation of periodontal ligament stem cells	29
Rheological properties of the human and porcine oral mucosa	25
Exosomal circZNF638 promotes postmenopausal osteoporosis progression through MGAT1-mediated SMAD9 glycosylation	22
Mechanism of IRF8 on osteocyte apoptosis in steroid-induced osteonecrosis of the femoral head	20
Tissue zone dependence and asymmetric distribution of membrane ruffles of in-situ bovine chondrocytes	15
Notum disrupts Wnt/β-catenin-mediated BMP9 osteogenesis in MSCs: implications for bone regeneration	12
Effects of intramuscular administration of Platelet-Rich Plasma on denervated muscle after peripheral nerve injury	12
Application of knee joint distraction: challenges and opportunities	12
Teriparatide prevented synovial inflammation and cartilage destruction in mice with DMM	11
Retinoic acid inhibits the pyroptosis of degenerated nucleus pulposus cells by activating Sirt1-SOD2 signaling	11
5α-dihydrotestosterone upregulates interferon signaling and limits osteoclast differentiation during inflammatory state	10
A gene expression and a histostructural analysis of the palmar fascia of patients affected by Dupuytren’s disease	10
Kaempferol binds with NSUN2 to mediate RNA 5-methylcytosine modification of BMP2 in osteogenic differentiation	10
Effects of dental pulp-derived mesenchymal stem cell exosomes produced under hypoxia conditions on osteoarthritic chondrocytes	10
The mechanism of lncRNA SNHG1 in osteogenic differentiation via miR-497-5p/ HIF1AN axis	8
PELI1 silencing delays intervertebral disc degeneration by impeding nucleus pulposus cell death	8
LncRNA SNHG7 inhibits apoptosis and proliferation of osteoarthritis cells induced by IL-β through sponging miR-146b	8
Acidosis induces significant changes to the murine supraspinatus enthesis organic matrix	7
Key insights and implications of cartilage degradation in osteoarthritis	7
Oncostatin M attenuates tumor necrosis factor-α-induced synthesis of macrophage-colony stimulating factor via suppression of Akt in osteoblasts	7
Comparative evaluation and optimization of amniotic membrane derived bioscaffold for bone regeneration in critical sized bone defect in rabbit radius model	7
Clinical and molecular landscape of post-traumatic osteoarthritis	7
Assembly of collagen fibers into contiguous dense and loose regions of subcutaneous fascia	7
miR-20a: a key regulator of orthodontic tooth movement via BMP2 signaling pathway modulation	7

Statement of Removal: Microengineering the synovial membrane microenvironment for osteoarthritis research	6
Cross-regulation of inflammation and metabolic mechanisms in osteoarthritis: recent advances bridging the gap to novel treatments	6
Sclerostin antibody promotes bone formation through the Wnt/β-catenin signaling pathway in femoral trochlear after patellar instability	6
Connections give strength: building next layer of Connective Tissue Research	6
The nuclear localization sequence and C-terminus of parathyroid hormone-related protein regulate chondrocyte development in epiphyseal growth cartilage	6
Overexpression of NSUN3 suppresses ferroptosis in osteoarthritis chondrocytes by reducing m5C modification and expression of PCBP1 mRNA	6
Biomechanical outcomes of pharmacological therapies for post-traumatic arthrofibrosis in preclinical animal models: a systematic review and meta-analysis	5
Peptide p[63–82] induces transcriptomic alterations associated with processes involved in cartilage repair in osteoarthritic human chondrocytes	5
The beneficial and detrimental effects of exercise and unloading on OA progression after anterior cruciate ligament injury	5
Cellular and molecular mechanisms underlying subchondral bone remodeling and associated pain in osteoarthritis	5
Lumican stimulates osteogenic differentiation in bone marrow-derived mesenchymal stem cells through glycolytic reprogramming to alleviate osteoporosis	5
Gelatin but not type I collagen promotes bacteria phagocytosis in PMA-treated U937 human lymphoma cells	5
TGF-β1 requires IL-13 to sustain collagen accumulation and increasing tissue strength and stiffness	5
miR-34a-5p facilitates osteogenic differentiation of bone marrow mesenchymal stem cells and modulates bone metabolism by targeting HDAC1 and promoting ER-α transcription	4
Application of gene therapy in osteoarthritis	4
LPS-induced inflammation potentiates dental pulp stem cell odontogenic differentiation through C5aR and p38	4
Notch1 is a marker for in situ resting osteocytes in a 3-dimensional gel culture model	4
A tribute to doctor Arthur Veis	4
Mechanics and differential healing outcomes of small and large defect injuries of the tendon-bone attachment in the rat rotator cuff	4
Advancements in understanding the role of obesity in osteoarthritis	4
Combination ex vivo regional gene therapy with sonic hedgehog and bone morphogenetic protein-2 does not enhance bone healing in critical size defects	4
Flow cytometric identification of dynamic immune cell populations in a rat model of post-traumatic elbow contracture	4
Charting the evolving paradigm of osteoarthritis research	4
Preliminary study of extracorporeal shock wave alleviating joint capsule fibrosis caused by internal bleeding of knee joint in rats	4
Drug repurposing for osteoarthritis disease modification in the early 21 ^st century	4
Dapagliflozin attenuates lipotoxic tenocyte injury via PPARα activation and irisin-driven antioxidant pathways	4
Nutrient deprivation of tendon-derived cells and its effect on collagen matrix integrity – mimicking graft remodelling after ACL reconstruction in vitro	4
Rotenone impairs osteoclastogenesis by inhibiting cell migration: insights from machine learning	4