OOIR: Observatory of International Research

Papers

(The median citation count of Connective Tissue Research is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Maresin-1 suppresses IL-1β-induced MMP-13 secretion by activating the PI3K/AKT pathway and inhibiting the NF-κB pathway in synovioblasts of an osteoarthritis rat model with treadmill exercise	29
The role of the tendon ECM in mechanotransduction: disruption and repair following overuse	19
LncRNA SNHG5 promotes chondrocyte proliferation and inhibits apoptosis in osteoarthritis by regulating miR-10a-5p/H3F3B axis	19
Regulation of chondrocyte biosynthetic activity by dynamic hydrostatic pressure: the role of TRP channels	17
Extracellular matrix at the muscle – tendon interface: functional roles, techniques to explore and implications for regenerative medicine	17
Compression stress induces nucleus pulposus cell autophagy by inhibition of the PI3K/AKT/mTOR pathway and activation of the JNK pathway	17
GREM1 inhibits osteogenic differentiation, senescence and BMP transcription of adipose-derived stem cells	15
Spatial frequency metrics for analysis of microscopic images of musculoskeletal tissues	15
Shikonin induces odontoblastic differentiation of dental pulp stem cells via AKT–mTOR signaling in the presence of CD44	14
RANKL expression of primary osteoblasts is enhanced by an IL-17-mediated JAK2/STAT3 pathway through autophagy suppression	14
Magnolin exhibits anti-inflammatory effects on chondrocytes via the NF-κB pathway for attenuating anterior cruciate ligament transection-induced osteoarthritis	14
Multiomics analysis of the mdx/mTR mouse model of Duchenne muscular dystrophy	14
Fluid shear stress-induced down-regulation of microRNA-140-5p promotes osteoblast proliferation by targeting VEGFA via the ERK5 pathway	13
Temporal changes in the muscle extracellular matrix due to volumetric muscle loss injury	12
Methods for studying MLO-Y4 osteocytes in collagen-hydroxyapatite scaffolds in the rotary cell culture system	11
An inducible model for unraveling the effects of advanced glycation end-product accumulation in aging connective tissues	11
Proanthocyanidins inhibit the apoptosis and aging of nucleus pulposus cells through the PI3K/Akt pathway delaying intervertebral disc degeneration	11
The potential role of mechanosensitive ion channels in substrate stiffness-regulated Ca²⁺response in chondrocytes	11
Ontogeny informs regeneration: explant models to investigate the role of the extracellular matrix in cartilage tissue assembly and development	11
Naringin inhibits titanium particles-induced up-regulation of TNF-α and IL-6 via the p38 MAPK pathway in fibroblasts from hip periprosthetic membrane	10
Expression of extracellular matrix components and cytokine receptors in human fibrocytes during rheumatoid arthritis	10
Downregulation of lncRNA XIST promotes proliferation and differentiation, limits apoptosis of osteoblasts through regulating miR-203-3p/ZFPM2 axis	10
Cellular alterations and crosstalk in the osteochondral joint in osteoarthritis and promising therapeutic strategies	10
Optogenetic activation of muscle contraction in vivo	9
Identification of key potential targets for TNF-α/TNFR1-related intervertebral disc degeneration by bioinformatics analysis	9

Collagens I and V differently regulate the proliferation and adhesion of rat islet INS-1 cells through the integrin β1/E-cadherin/β-catenin pathway	8
HOXA10 inhibit the osteogenic differentiation of periodontal ligament stem cells by regulating β-catenin localization and DKK1 expression	8
The role of SLRPs and large aggregating proteoglycans in collagen fibrillogenesis, extracellular matrix assembly, and mechanical function of fibrocartilage	8
Comparison of the efficiency of laminin versus fibronectin as a differential adhesion assay for isolation of human articular cartilage derived chondroprogenitors	8
Pleiotropin enhances the osteo/dentinogenic differentiation potential of dental pulp stem cells	8
Proteoglycan-4 and hyaluronan composition in synovial fluid and serum from clinical equine subjects: relationship to cartilage boundary lubrication and viscosity of synovial fluid	8
Effects of Raloxifene and tibial loading on bone mass and mechanics in male and female mice	8
Metformin reduces myogenic contracture and myofibrosis induced by rat knee joint immobilization via AMPK-mediated inhibition of TGF-β1/Smad signaling pathway	7
Therapeutic potential of mesenchymal stem cell-derived exosomes as a cell-free therapy approach for the treatment of skin, bone, and cartilage defects	7
Effects of osteogenic ambulatory mechanical stimulation on early stages of BMP-2 mediated bone repair	7
Radial extracorporeal shock wave reduces myogenic contracture and muscle atrophy via inhibiting NF-κB/HIF-1α signaling pathway in rabbit	7
Collagen misfolding mutations: the contribution of the unfolded protein response to the molecular pathology	7
Therapeutic application of extracellular vesicles for musculoskeletal repair & regeneration	7
Sema3A accelerates bone formation during distraction osteogenesis in mice	7
Inhibition of RhoA/MRTF-A signaling alleviates nucleus pulposus fibrosis induced by mechanical stress overload	7
PBN protects NP cells from AAPH-induced degenerative changes by inhibiting the ERK1/2 pathway	7
Regenerative rehabilitation of catastrophic extremity injury in military conflicts and a review of recent developmental efforts	7
Volumetric muscle loss disrupts length-dependent architectural and functional characteristics of skeletal muscle	7
Stress-deprivation induces an up-regulation of versican and connexin-43 mRNA and protein synthesis and increased ADAMTS-1 production in tendon cells in situ	6
Clinical and laboratory findings following transplantation of allogeneic adipose-derived mesenchymal stromal cells in knee osteoarthritis, a brief report	6
Axin2-lineage cells contribute to neonatal tendon regeneration	6
Impact of aging on tendon homeostasis, tendinopathy development, and impaired healing	6
Development of a novel knee contracture mouse model by immobilization using external fixation	6
Extracellular vesicles from human umbilical cord mesenchymal stem cells reduce lipopolysaccharide-induced spinal cord injury neuronal apoptosis by mediating miR-29b-3p/PTEN	6
C5a complement receptor modulates odontogenic dental pulp stem cell differentiation under hypoxia	6
Role of Nrf2 and HO-1 in intervertebral disc degeneration	6
Blocking CCN2 preferentially inhibits osteoclastogenesis induced by repetitive high force bone loading	6
Ex vivo models of musculoskeletal tissues	5
Influence of the site of injury on the spontaneous healing response in a rat model of total rupture of the anterior cruciate ligament	5
Potential cross-talk between muscle and tendon in Duchenne muscular dystrophy	5
Comparison of dynamic mechanical properties of dentin between deciduous and permanent teeth	5
Effect of bone marrow mesenchymal stem cell transplantation combined with lugua polypeptide injection on osteoarthritis in rabbit knee joint	5
Comparison between placental and skeletal muscle ECM: in vivo implantation	5
Responses of matrix metalloproteinases to hyperbaric oxygen treatment: changing for good or ill?	5
Minoxidil decreases collagen I deposition and tissue-like contraction in clubfoot-derived cells: a way to improve conservative treatment of relapsed clubfoot?	5
Chondrocyte morphology as an indicator of collagen network integrity	5
Diversity in heritable disorders of connective tissue at a single center	5
Force dependent effects of chronic overuse on fibrosis-related genes and proteins in skeletal muscles	5
Oral mucosa equivalents, prevascularization approaches, and potential applications	5
MiR-151b inhibits osteoblast differentiation via downregulating Msx2	4
Basement membrane recovery process in rat soleus muscle after exercise-induced muscle injury	4
Role of pro-inflammatory interleukins in osteoarthritis: a narrative review	4
Osteogenic capacity of mesenchymal stem cells from patients with osteoporotic hip fractures in vivo	4
Characterization of murine subacromial bursal-derived cells	4
PDGF-AA promotes gap junction intercellular communication in chondrocytes via the PI3K/Akt pathway	4
Acceleration of pelvic tissue generation by overexpression of basic fibroblast growth factor in stem cells	4
Overexpression of laminin α4 facilitates proliferation and migration of fibroblasts in knee arthrofibrosis by targeting canonical Shh/Gli1 signaling	4
Osteoarthritic meniscal entheses exhibit altered collagen fiber orientation	4
RHOA inhibits chondrogenic differentiation of mesenchymal stem cells in adolescent idiopathic scoliosis	3
The effects of the amount of weight bearing on articular cartilage early after ACL reconstruction in rats	3

Differential MMP 1 and MMP 13 expression in proliferation and ligamentization phases of graft remodeling in anterior cruciate ligament reconstruction	3
Exercise-driven exacerbation of inflammation: contribution of animal models of rheumatoid arthritis and spondyloarthritis	3
Cyclic mechanical stretch regulates the AMPK/Egr1 pathway in tenocytes via Ca2+-mediated mechanosensing	3
Effects of non-steroidal anti-inflammatory drug (ibuprofen) in low and high dose on stemness and biological characteristics of human dental pulp-derived mesenchymal stem cells	3
Clinical, genetic characteristics and treatment outcomes of children and adolescents with osteogenesis imperfecta: a two-center experience	3
Contribution of immune cells to intervertebral disc degeneration and the potential of immunotherapy	3
Teriparatide prevented synovial inflammation and cartilage destruction in mice with DMM	3