Molecular and Cellular Biochemistry

Article	Citations
CircEXOC5 facilitates cell pyroptosis via epigenetic suppression of Nrf2 in septic acute lung injury	203
Lnc PVT1 facilitates TGF-β1-induced human cardiac fibroblast activation in vitro and ISO-induced myocardial fibrosis in vivo through regulating MYC	201
Activated TREM1-mediated MAPK signaling in endothelial cells caused by highly expressed STAT1 is associated with intracranial aneurysms occurrence and rupture	147
CircHAT1 regulates the proliferation and phenotype switch of vascular smooth muscle cells in lower extremity arteriosclerosis obliterans through targeting SFRS1	81
Anti-inflammatory effects and gut microbiota modulation of synbiotic mulberry in DSS-induced colitis rats	76
Nicaraven attenuates the acquired radioresistance of established tumors in mouse models via PARP inhibition	69
Protective effect of exosomes derived from platelet-rich plasma during human sperm cryopreservation	65
Sodium butyrate attenuates liver fibrogenesis via promoting H4K8 crotonylation	55
TRIM46 upregulates Wnt/β-catenin signaling by inhibiting Axin1 to mediate hypoxia-induced epithelial–mesenchymal transition in HK2 cells	55
HSF4 promotes tumor progression of colorectal cancer by transactivating c-MET	50
Retraction Note: Microrheological disorders in patients with polycythemia vera suffered acute ischemic stroke	48
Extracellular vesicles derived from bone marrow mesenchymal stem cells ameliorate liver fibrosis via micro-7045-5p	48
Retraction Note: Thrombin stimulates VSMC proliferation through an EGFR-dependent pathway: involvement of MMP-2	48
miR-4299 inhibits tumor progression in pancreatic cancer through targeting ADAM17	47
Retraction Note: Arginase inhibitor attenuates pulmonary artery hypertension induced by hypoxia	46
Retraction Note: MiRNA-27a mediates insulin resistance in 3T3-L1 cells through the PPARγ	45
Insights into non-coding RNAS: biogenesis, function and their potential regulatory roles in acute kidney disease and chronic kidney disease	44
Production of Duchenne muscular dystrophy cellular model using CRISPR-Cas9 exon deletion strategy	44
The role of prickle proteins in vertebrate development and pathology	44
Stability and expression of SARS-CoV-2 spike-protein mutations	42
Angiopoietin-like protein 2 inhibits thrombus formation	40
NRF2 signaling pathway and telomere length in aging and age-related diseases	39
ACSL4 accelerates osteosarcoma progression via modulating TGF-β/Smad2 signaling pathway	39
STK32C modulates doxorubicin resistance in triple-negative breast cancer cells via glycolysis regulation	38
Exosomes derived from human umbilical cord mesenchymal stem cells decrease neuroinflammation and facilitate the restoration of nerve function in rats suffering from intracerebral hemorrhage	37

Erythronecroptosis: an overview of necroptosis or programmed necrosis in red blood cells	37
Ferroptosis in TNBC: interplay with tumor-infiltrating immune cells and therapeutic implications	36
Intermittent fasting and exercise: a dual intervention for orchestrating glycolipid conversion and utilization in healthy mice	35
Gut microbiota regulates gut homeostasis, mucosal immunity and influences immune-related diseases	34
Untargeted metabolomics identifies indole-3-propionic acid to relieve Ang II-induced endothelial dysfunction in aortic dissection	34
MTMR7 attenuates the proliferation and migration of pulmonary arterial smooth muscle cells in pulmonary hypertension by suppressing ERK/STAT3 signaling	33
Analyses of oxidative DNA damage among coal vendors via single cell gel electrophoresis and quantification of 8-hydroxy-2’-deoxyguanosine	32
The role of resistin and adiponectin ratios with uric acid in assessing metabolic syndrome in type 2 diabetes	32
P311 knockdown alleviates hyperoxia-induced injury by inactivating the Smad3 signaling pathway in type II alveolar epithelial cells	32
SNORC knockdown alleviates inflammation, autophagy defect and matrix degradation of chondrocytes in osteoarthritis development	31
Current advances in human-induced pluripotent stem cell-based models and therapeutic approaches for congenital heart disease	30
Investigation of homocysteine, D-dimer and platelet count levels as potential predictors of thrombosis risk in COVID-19 patients	30
Drugs targeting TGF-β/Notch interaction attenuate hypertrophic scar formation by optic atrophy 1-mediated mitochondrial fusion	30
Synaptic-mitochondrial transport: mechanisms in neural adaptation and degeneration	29
Myocardial infarction serum preconditioning bone marrow mesenchymal stem cell-derived exosomes enhance anti-fibrosis in rat myocardial infarction hearts	29
Tempol and silymarin rescue from zinc-induced degeneration of dopaminergic neurons through modulation of oxidative stress and inflammation	28
Angiogenic Markers in Gestational Diabetes and their Association with Placental Dimensions	28
Mechanisms and clinical landscape of N6-methyladenosine (m6A) RNA modification in gastrointestinal tract cancers	27
AMPK/mTOR balance during exercise: implications for insulin resistance in aging muscle	26
Ferroptosis: a potential therapeutic target in cardio-cerebrovascular diseases	26
Exosome isolation based on polyethylene glycol (PEG): a review	26
The study of the mechanism of non-coding RNA regulation of programmed cell death in diabetic cardiomyopathy	26
Mitochondria and NLRP3 inflammasome in cardiac hypertrophy	25
Molecular mechanisms of ferroptosis in cardiovascular disease	25
Unlocking cardiac health: exploring the role of class I HDACs in cardiovascular diseases	24
Correction to: Irisin: muscle’s novel player in endoplasmic reticulum stress and disease	24
Correction: miR-206 alleviates LPS-induced inflammatory injury in cardiomyocytes via directly targeting USP33 to inhibit the JAK2/STAT3 signaling pathway	24
Phosphorylation of RasGRP1 by Shc3 prevents RasGRP1 degradation and contributes to Ras/c-Jun activation in hepatocellular carcinoma	24
ER stress improvement by aerobic training or enalapril differently ameliorates pathological cardiac remodeling in obese mice	24
The impact of combination of zofenopril and different diuretics on regression of myocardial reperfusion injury and oxidative status in spontaneously hypertensive rats	23
Effects of resveratrol on inflammatory cytokines in COVID-19 patients: a randomized, double-blinded, placebo-controlled clinical trial	23
Silencing lncRNA KCNQ1OT1 reduced hepatic ischemia reperfusion injury-induced pyroptosis by regulating miR-142a-3p/HMGB1 axis	23
Optimizing human endometrial mesenchymal stem cells for maximal induction of angiogenesis	23
Developing therapeutic approaches for chronic myeloid leukemia: a review	23
Retraction Note: The importance of vitamin D in the diagnosis and treatment of adenomyosis	23
Effects of a physical exercise or motor activity protocol on cognitive function, lipid profile, and BDNF levels in older adults with mild cognitive impairment	23
Development and classification of RNA aptamers for therapeutic purposes: an updated review with emphasis on cancer	22
Rheumatoid arthritis: advances in treatment strategies	22
The effect of TMAO on aging-associated cardiovascular and metabolic pathways and emerging therapies	22
The role of HBV cccDNA in occult hepatitis B virus infection	22
Protein kinase CK2 phosphorylates a conserved motif in the Notch effector E(spl)-Mγ	21
Insights into the C-terminal domain of apolipoprotein E from chimera studies with apolipophorin III	21
Aberrant formation of the neutrophil extracellular trap and the expression of the PLEKHA1 in systemic lupus erythematosus and ulcerative colitis	21
A novel identified circular RNA, circSnap47, promotes heart failure progression via regulation of miR-223-3p/MAPK axis	21
Molecular characterization underlying IFN-α2 treatment in polycythemia vera: a transcriptomic overview	21
The role of the mitochondrial trans-sulfuration in cerebro-cardio renal dysfunction during trisomy down syndrome	20
Twist alters the breast tumor microenvironment via choline kinase to facilitate an aggressive phenotype	20
Swimming exercise activates peroxisome proliferator-activated receptor-alpha and mitigates age-related renal fibrosis in rats	20
Repurposing FDA-approved drugs as inhibitors of therapy-induced invadopodia activity in glioblastoma cells	20
The gut microbiota-NLRP3 inflammasome connection: current evidence and perspectives for non-communicable diseases	20

Ferroptosis: a new promising target for hepatocellular carcinoma therapy	20
Correction to: Melatonin antagonizes oxidative stress-induced apoptosis in retinal ganglion cells through activating the thioredoxin-1 pathway	20
Downregulation of PRMT5 by AMI-1 enhances therapeutic efficacy of compound kushen injection in lung carcinoma in vitro and in vivo	20
Intermittent fasting shifts the diurnal transcriptome atlas of transcription factors	19
Retraction Note: Downregulation of long non-coding RNA TUG1 suppresses tumor growth by promoting ubiquitination of MET in diffuse large B-cell lymphoma	19
Vitamin D accelerates the subdural hematoma clearance through improving the meningeal lymphatic vessel function	19
Lymphoid tissue inducer cells in cancer: a potential therapeutic target	19
Follistatin-like protein 1 attenuates doxorubicin-induced cardiomyopathy by inhibiting MsrB2-mediated mitophagy	19
Retraction Note: Forkhead factor FOXQ1 promotes TGF-β1 expression and induces epithelial–mesenchymal transition	19
Editorial Expression of Concern: Induction of HRR genes and inhibition of DNMT1 is associated with anthracycline anti-tumor antibiotic-tolerant breast carcinoma cells	18
Therapeutic role of kaempferol and myricetin in streptozotocin-induced diabetes synergistically via modulation in pancreatic amylase, glycogen storage and insulin secretion	18
The dark side of SIRT7	18
The frequency of the ACE I/D polymorphism in South America: a systematic review and meta-analysis	18
Catechin promotes endoplasmic reticulum stress-mediated gastric cancer cell apoptosis via NOX4-induced reactive oxygen species	18
Chemopreventive aspects, investigational anticancer applications and current perspectives on allyl isothiocyanate (AITC): a review	18
Endothelium Piezo1 deletion alleviates experimental varicose veins by attenuating perivenous inflammation	17
Salidroside overcomes cisplatin resistance in ovarian cancer via the inhibition of CRNDE-mediated autophagy	17
The multifaceted nature of SUMOylation in heart disease and its therapeutic potential	17
Alpha-1-antitrypsin in serum exosomes and pericardial fluid exosomes is associated with severity of rheumatic heart disease	17
Ribosomal proteins: the missing piece in the inflammation puzzle?	17
Mechanisms and therapeutic prospect of the JAK-STAT signaling pathway in liver cancer	17
Erythropoietin promotes energy metabolism to improve LPS-induced injury in HK-2 cells via SIRT1/PGC1-α pathway	17
Metformin role in Parkinson’s disease: a double-sword effect	17
Characterization of intestinal microbiota in patients with psoriasis combined with metabolic syndrome	17
Correction to: Macrophage energy metabolism in cardiometabolic disease	16
The role of WWP1 and WWP2 in bone/cartilage development and diseases	16
Retraction Note: A miR‑1275 mimic protects myocardiocyte apoptosis by regulating the Wnt/NF‑κB pathway in a rat model of myocardial ischemia–reperfusion‑induced myocardial injury	16
LncRNA HCG18 promotes inflammation and apoptosis in intervertebral disc degeneration via the miR-495-3p/FSTL1 axis	16
Tanshinone IIA (TSIIA) represses the progression of non-small cell lung cancer by the circ_0020123/miR-1299/HMGB3 pathway	16
HuD and alpha-crystallin A axis protects neuro-retinal cells in early diabetes	16
Cholesterol suppresses AMFR-mediated PDL1 ubiquitination and degradation in HCC	16
Selenocoxib-3, a novel anti-inflammatory therapeutic effectively resolves colitis	16
Retraction Note: The levels of pro- and anti-inflammatory cytokines in premature infants with perinatal infections	16
Emerging role of lipophagy in liver disorders	16
Retraction Note: Baicalin augments the differentiation of osteoblasts via enhancement of microRNA-217	16
Correction: Exosomes from circRNA-Ptpn4 can modify ADSC treatment and repair nerve damage caused by cerebral infarction by shifting microglial M1/M2 polarization	16
Targeting RAGE-signaling pathways in the repair of rotator-cuff injury	16
Exploring the potential link between human papillomavirus infection and coronary artery disease: a review of shared pathways and mechanisms	16
Vagus nerve stimulation (VNS) preventing postoperative cognitive dysfunction (POCD): two potential mechanisms in cognitive function	16
Circular RNAs: key players in tumor immune evasion	16
Circ_0090231 knockdown protects vascular smooth muscle cells from ox-LDL-induced proliferation, migration and invasion via miR-942-5p/PPM1B axis during atherosclerosis	16
Exploring exhaled volatile organic compounds as potential biomarkers in anti-MDA5 antibody-positive interstitial lung disease	15
Effects of four weeks lasting aerobic physical activity on cardiovascular biomarkers, oxidative stress and histomorphometric changes of heart and aorta in rats with experimentally induced hyperhomocys	15
Treating diabetes with combination of phosphodiesterase 5 inhibitors and hydroxychloroquine—a possible prevention strategy for COVID-19?	15
Respiratory issues in patients with multiple sclerosis as a risk factor during SARS-CoV-2 infection: a potential role for exercise	15
TXNIP knockdown ameliorates hepatic ischemia/reperfusion injury by inhibiting apoptosis and improving mitochondrial dysfunction via HIF-1α	15
Eupatilin ameliorates postmenopausal osteoporosis via elevating microRNA-211-5p and repressing Janus kinase 2/Signal transducer and activator of transcription 3 pathway	15
Relevance and mechanism of STAT3/miR-221-3p/Fascin-1 axis in EGFR TKI resistance of triple-negative breast cancer	15
The role of Nod-like receptor protein 3 inflammasome activated by ion channels in multiple diseases	15
NEK2 affects the ferroptosis sensitivity of gastric cancer cells by regulating the expression of HMOX1 through Keap1/Nrf2	15
Abnormal upregulation of NUBP2 contributes to cancer progression in colorectal cancer	15
Regional heterogeneity in vascular contractile dysfunction in diabetic mice	14
Walnut supplementation increases levels of UCP1 and CD36 in brown adipose tissue independently of diet type	14
Tumor microenvironment noise-induced polarization: the main challenge in macrophages’ immunotherapy for cancer	14
Mechanistic insight and structure activity relationship of isatin-based derivatives in development of anti-breast cancer agents	14
TOR1 AIP1 interacts with p53 to enhance cell cycle dysregulation in prostate cancer progression	14
LncRNA GNAS-AS1 knockdown inhibits keloid cells growth by mediating the miR-188-5p/RUNX2 axis	14
Disrupting of IGF2BP3-stabilized HK2 mRNA by MYO16-AS1 competitively binding impairs LUAD migration and invasion	13
METTL1-mediated m7G modification promotes colorectal cancer metastasis via stabilization of ICAM-1	13
The pharmaco-epigenetics of hypertension: a focus on microRNA	13
NR1H4-mediated circRHOBTB3 modulates the proliferation, metastasis, and Warburg effects of cervical cancer through interacting with IGF2BP3	13
Development of quantitative PCR and digital PCR for the quantification of Leishmania infantum in dogs	13
A new perspective on the autophagic and non-autophagic functions of the GABARAP protein family: a potential therapeutic target for human diseases	13
SGLT2i continuously prevents cardiac hypertrophy by reducing ferroptosis via AMPK up-regulation	13
Investigation of effects of transferrin-conjugated gold nanoparticles on hippocampal neuronal activity and anxiety behavior in mice	13
Retraction Note: Curcumin amends Ca2 + dysregulation in microglia by suppressing the activation of P2 × 7 receptor	13
Biochemical characterization of clinically relevant mutations of human Translin	13
Mitochondrial complex-1 as a therapeutic target for cardiac diseases	13
Loss of FAM172A gene prompts cell proliferation in liver regeneration	13
Mitochondrial disease management through phytochemical interventions	13
Toll-like receptors polymorphisms and COVID-19: a systematic review	13
Single-cell atlas profiling revealed cellular characteristics and dynamic changes after PD-1 blockade therapy of brain metastases from laryngeal squamous cell carcinoma	13
Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission	13
Triphenyltin isoselenocyanate: a novel nuclear retinoid X receptor ligand with antiproliferative and cytotoxic properties in cell lines derived from human breast cancer	13
Mitochondrial Dysfunction-Molecular Mechanisms and Potential Treatment approaches of Hepatocellular Carcinoma	13
Downregulation of glycoprotein non-metastatic melanoma protein B prevents high glucose-induced angiogenesis in diabetic retinopathy	13
Development of stem cell therapy for atherosclerosis	12
Recent progress on anti-nociceptive effects of carbon monoxide releasing molecule-2 (CORM-2)	12
A systematic review of cell therapy modalities and outcomes in cerebral palsy	12
Inhibitors of gastric acid secretion increase oxidative stress and matrix metalloproteinase-2 activity leading to vascular remodeling	12

A review on the epigenetic regulation of testosterone synthesis in Leydig cells	12
Anti-OAcGD2 antibody in combination with ceramide kinase inhibitor mediates potent antitumor cytotoxicity against breast cancer and diffuse intrinsic pontine glioma cells	12
The challenges and progress of CAR-T cell therapy in the treatment of solid tumors	12
Human amniotic membrane scaffold enhances adipose mesenchymal stromal cell mitochondrial bioenergetics promoting their regenerative capacities	12
Role of AMP deaminase in diabetic cardiomyopathy	12
Global trend in exosome isolation and application: an update concept in management of diseases	12
Molecular pathways and therapeutic targets linked to triple-negative breast cancer (TNBC)	12
Retraction Note to: Expression patterns of AMP-deaminase isozymes in human hepatocellular carcinoma (HCC)	12
Inhibition of STRA6 suppresses NSCLC growth via blocking STAT3/SREBP-1c axis-mediated lipogenesis	12
Advancing Parkinson’s diagnosis: seed amplification assay for α-synuclein detection in minimally invasive samples	12
Punicalagin protects against the development of pancreatic injury and insulitis in rats with induced T1DM by reducing inflammation and oxidative stress	12
The truncated AXIN1 isoform promotes hepatocellular carcinoma metastasis through SRSF9-mediated exon 9 skipping	12
Computational insights into NIMA-related kinase 6: unraveling mutational effects on structure and function	12
The E2F family: a ray of dawn in cardiomyopathy	12
Research advances in branched-chain amino acid metabolism in tumors	12
The gut microbiome: an important role in neurodegenerative diseases and their therapeutic advances	12
How does caspases regulation play role in cell decisions? apoptosis and beyond	12
Constructed the ceRNA network and predicted a FEZF1-AS1/miR-92b-3p/ZIC5 axis in colon cancer	12
N6-methyladenosine-induced miR-182-5p promotes multiple myeloma tumorigenesis by regulating CAMK2N1	12
Single cell transcription revealing key transcription factors in embryonic kidney development	12
Deciphering the enigma: long noncoding RNAs in disease pathogenesis and therapeutic prospects	12
Let-7c-3p suppresses lens epithelial-mesenchymal transition by inhibiting cadherin-11 expression in fibrotic cataract	12
The bone-vascular axis: the link between osteoporosis and vascular calcification	12
Residual risks and evolving atherosclerotic plaques	12
The role of lncRNA-ZFAS1 in liver fibrosis: insights into the miR-1953/TAZ axis	12
Putative volatile biomarkers of bovine tuberculosis infection in breath, skin and feces of cattle	12
The effects of N6-methyladenosine RNA methylation on the nervous system	12
Chronic stress, gut microbiota, and immunity: interconnections and implications for health	12
STAT3 mediates ECM stiffness-dependent progression in ovarian cancer	11
M2 macrophage-derived exosomes carry miR-142-3p to restore the differentiation balance of irradiated BMMSCs by targeting TGF-β1	11
circSKA3 promotes colorectal cancer metastases through miR-1238 and methylation	11
The role of mitochondrial dysfunction in the protective effect of ginger derived extracellular vesicles on hepatic stellate cells against cytotoxicity	11
The SIRT1/GPS2/AIP1 axis regulates pulmonary vascular permeability in ventilator-induced lung injury	11
Causal effect of systolic blood pressure on myocardial injury and mortality: insights from Mendelian randomization and a prospective group study	11
Low-intensity exercise prevents cardiac inflammation through the NF-κB/TNFα pathway in insulin-resistant male rats	11
miR-206 alleviates LPS-induced inflammatory injury in cardiomyocytes via directly targeting USP33 to inhibit the JAK2/STAT3 signaling pathway	11
Molecular mechanisms of morphine tolerance and dependence; novel insights and future perspectives	11
Effect of PI3K/AKT/mTOR signaling pathway-based clustered nursing care combined with papaverine injection on vascular inflammation and vascular crisis after replantation of severed fingers	11
Re. Re.: “Immunothrombotic dysregulation in Chagas disease and COVID19: a comparative study of anticoagulation”	11
STING agonist, SMA-2, inhibits clear cell renal cell carcinoma through improving tumor microenvironment	11
BsmI, ApaI and FokI variants of vitamin D receptor gene polymorphism as predictors of response to treatment in immune thrombocytopenia patients	11
Plant polysaccharides and antioxidant benefits for exercise performance and gut health: from molecular pathways to clinic	11
PGC-1α participates in tumor chemoresistance by regulating glucose metabolism and mitochondrial function	11
Human-induced pluripotent stem cell-derived exosomes promote skin wound healing through activating FGF2-mediated p38 pathway	11
Single-cell RNA sequencing generates an atlas of normal tibia cartilage under mechanical loading conditions	11
Isolation methods, proliferation, and adipogenic differentiation of adipose-derived stem cells from different fat depots in bovines	11
Retraction Note: Tactics for treating young children with pyelonephritis and vesicoureteral reflux associated with impaired fibrillogenesis	11
MYH7 in cardiomyopathy and skeletal muscle myopathy	11
Multi-omics analysis identifies potential mechanisms by which high glucose accelerates macrophage foaming	11
A tribute to Prof. Naranjan S. Dhalla, former Editor-in-Chief of Molecular and Cellular Biochemistry	11
The highs and lows of monoamine oxidase as molecular target in cancer: an updated review	11
Cell-intrinsic factors governing quiescence vis-à-vis activation of adult hematopoietic stem cells	10
Correction to: The relationship between serum coagulation parameters and the recurrence of chronic subdural hematoma	10
Combinational delivery of TLR4 and TLR7/8 agonist enhanced the therapeutic efficacy of immune checkpoint inhibitors to colon tumor	10
The mechanisms of exercise improving cardiovascular function by stimulating Piezo1 and TRP ion channels: a systemic review	10
Retraction Note: Downregulation of Hyaluronic acid-CD44 signaling pathway in cervical cancer cell by natural polyphenols Plumbagin, Pongapin and Karanjin	10
Cell death crosstalk in respiratory diseases: unveiling the relationship between pyroptosis and ferroptosis in asthma and COPD	10
Neutrophil extracellular traps: a catalyst for atherosclerosis	10
Novel pyrrolidine-aminophenyl-1,4-naphthoquinones: structure-related mechanisms of leukemia cell death	10
A randomized controlled trial on the impact of anesthetic agents on renal function in cardiac surgery with cardiopulmonary bypass	10
Fibroblasts and mouse breast cancer cells can form cellular aggregates in improved soft agar culture medium	10
Empagliflozin and dapagliflozin decreased atrial monoamine oxidase expression and alleviated oxidative stress in overweight non-diabetic cardiac patients	10
Enhancing cardiac regeneration: direct reprogramming of fibroblasts into myocardial-like cells using extracellular vesicles secreted by cardiomyocytes	10
Neuroprotection elicited by taurine in sporadic Alzheimer-like disease: benefits on memory and control of neuroinflammation in the hippocampus of rats	10
The role of the farnesoid X receptor in diabetes and its complications	10
Significance of UGT1A6, UGT1A9, and UGT2B7 genetic variants and their mRNA expression in the clinical outcome of renal cell carcinoma	10
Important molecular mechanisms in ferroptosis	10
RETRACTED ARTICLE: Tactics for treating young children with pyelonephritis and vesicoureteral reflux associated with impaired fibrillogenesis	10
Retraction Note: Role of CC-chemokine receptor 5 on myocardial ischemia–reperfusion injury in rats	10
The role of estrogen in Alzheimer’s disease pathogenesis and therapeutic potential in women	10
A review of immune modulators and immunotherapy in infectious diseases	10
Exercise training decreases the load and changes the content of circulating SDS-resistant protein aggregates in patients with heart failure with reduced ejection fraction	10