Biochemical Society Transactions

Article	Citations
Structural insights into ferroportin mediated iron transport	201
CD95/Fas ligand induced toxicity	167
Advances in understanding telomerase assembly	93
Chemical catalysis by biological amyloids	87
The impact of amino acid metabolism on adult neurogenesis	83
Canonical and alternate mechanisms that regulate ubiquitylation by the E3 ligase parkin	68
Connecting tubules: mechanisms of endoplasmic reticulum membrane fusion	66
Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling	61
Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques	60
Inflammatory cell death: how macrophages sense neighbouring cell infection and damage	59
Negative regulation of biofilm formation by nitric oxide sensing proteins	56
Functions and mechanisms of eukaryotic RNA-guided programmed DNA elimination	50
Solid-state nuclear magnetic resonance in the structural study of polyglutamine aggregation	50
Caveolae and the oxidative stress response	49
Reconstituting membrane fission using a high content and throughput assay	49
Translation stalling in neurons: a critical mechanism for timely protein delivery to distal cellular processes	46
The pleiotropic roles of eIF5A in cellular life and its therapeutic potential in cancer	45
Mechanisms underpinning natural variation in non-photochemical quenching kinetics	45
Neurodevelopmental functions of CHD8: new insights and questions	45
Do tunneling nanotubes drive chemoresistance in solid tumors and other malignancies?	44
The role of autophagy-lysosomal pathway in motor neuron diseases	42
A dynamic role for transcription factors in restoring transcription through mitosis	42
The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI	42
Native mass spectrometry meets X-rays for the elucidation of protein structures	42
Experimental systems for the analysis of mutational signatures: no ‘one-size-fits-all' solution	42

Aminoacyl-tRNA synthetase interactions in SARS-CoV-2 infection	41
Compatibility of termination mechanisms in bacterial transcription with inference on eukaryotic models	41
Role of Yme1 in mitochondrial protein homeostasis: from regulation of protein import, OXPHOS function to lipid synthesis and mitochondrial dynamics	41
Maximizing the performance of protein-based fluorescent biosensors	40
The molecular mechanisms of diapause and diapause-like reversible arrest	39
The role of RHIM in necroptosis	38
Emerging roles for tumor stroma in antigen presentation and anti-cancer immunity	37
Spo11: from topoisomerase VI to meiotic recombination initiator	37
Joining forces: crosstalk between mechanosensitive PIEZO1 ion channels and integrin-mediated focal adhesions	36
Deconstructing cancer with precision genome editing	36
Exploring potential developmental origins of common neurodegenerative disorders	36
The role of lipid scramblases in regulating lipid distributions at cellular membranes	36
Structural switching of tubulin in the microtubule lattice	36
Periodic pattern formation during embryonic development	35
Correction: Current Working Models of SMC-driven DNA-loop extrusion	35
The long and the short of Periscope Proteins	35
The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder	35
Sensing of double-stranded RNA in human cells: molecular mechanisms and cellular consequences	33
Direct or indirect: the crucial role of N-palmitate in hedgehog signaling	33
New insights into the structure and dynamics of the TOM complex in mitochondria	31
Emerging concepts of reactive oxygen species functions in plants	31
The SMN-ribosome interplay: a new opportunity for Spinal Muscular Atrophy therapies	29
Transition from totipotency to pluripotency in mice: insights into molecular mechanisms	29
S-acylation in apoptotic and non-apoptotic cell death: a central regulator of membrane dynamics and protein function	28
Ribosomal RNA expansion segments and their role in ribosome biology	28
A busy BOD1-y: the diverse functions of an intracellular signaling regulatory protein family	27
G0 or no-G0: phosphatase control of quiescence and cell cycle entry	27
Heparan sulphate and neural development: dissecting the roles of astrocyte-expressed heparan sulphate	27
Structural glycobiology – from enzymes to organelles	27
Cryo-electron tomography: en route to the molecular anatomy of organisms and tissues	26
The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis	26
Recent insights into the control of mitochondrial fission	26
Expect the unexpected: conventional and unconventional roles for cadherins in collective cell migration	26
Frankenstein Cas9: engineering improved gene editing systems	26
The impact of psuedouridine modification on human tRNA	25
The role of peroxidasin in solid cancer progression	25
Ceramide microdomains: the major influencers of the sphingolipid media platform	24
Tetraspanins affect membrane structures and the trafficking of molecular partners: what impact on extracellular vesicles?	24
Extracellular membrane particles en route to the nucleus – exploring the VOR complex	24
Novel roles for G protein-coupled receptor kinases in cardiac injury and repair	24
Mechanisms influencing transient cytoplasmic protein targeting to intracellular lipid droplets	24
Correction: Fast-forward on P-type ATPases: recent advances on structure and function	24
Mre11–Rad50: the DNA end game	24
Is the SPLUNC1-Orai1 axis a critical determinant of lung health?	24
The octadecanoids: an emerging class of lipid mediators	24
Covalent activity-based probes for imaging of serine proteases	24
Structural insights into the membrane-bound proteolytic machinery of bacterial protein quality control	24
Research progress of ZIC5 for tumor metastasis	24
Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein	23
Straight A’s: protein S-acylation in the activation and autophagic degradation of NOD-like receptors	23

Advances in understanding Ton and Tol system motor proteins	23
DDX41: exploring the roles of a versatile helicase	23
General strategies for using amino acid sequence data to guide biochemical investigation of protein function	23
The central role of translation elongation in response to stress	23
Voltage-clamp fluorometry for advancing mechanistic understanding of ion channel mechanisms with a focus on acid-sensing ion channels	23
Bottom-up reconstitution of model membrane systems: a mini-review	22
Understanding adipocyte heterogeneity across species, depot, and disease	22
Sculpting with stiffness: rigidity as a regulator of morphogenesis	22
Uncovering novel regulators of memory using C. elegans genetic and genomic analysis	22
The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer	22
Structural basis of molecular recognition among classical cadherins mediating cell adhesion	22
The mechanisms of alkali therapy in targeting renal diseases	22
Designing de novo TIM barrels: insights into stabilization, diversification, and functionalization strategies	21
Folding speeds of helical membrane proteins	21
FASTK post-transcriptional regulators – a ‘FAST-tracK’ in mitochondrial gene expression	21
Correction: Emerging roles for tumor stroma in antigen presentation and anti-cancer immunity	21
A pore is a pore is a pore (or a hub?): VDAC oligomerization in mitochondrial connectivity and modulation	21
Understanding the role of ten-eleven translocation family proteins in kidney diseases	21
Transcriptional control of neural stem cell activity	21
Sometimes less is more: inhibitory infrared light during early reperfusion calms hyperactive mitochondria and suppresses reperfusion injury	21
S-acylation of Ca2+ transport proteins: molecular basis and functional consequences	21
The influence of high-order chromatin state in the regulation of stem cell fate	21
Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery	21
Implications of Rho GTPase signaling in cancer immunotherapy	20
How does the tubulin code facilitate directed cell migration?	20
Advancing the monitoring of organelle contact sites in vitro and in vivo	20
Plant supercomplex I + III2 structure and function: implications for the growing field	20
Chlamydia trachomatis invasion: a duet of effectors	20
Transcriptional bursting: from fundamentals to novel insights	20
Role of post-translational modifications in modulating histone reactivity in the extracellular environment	20
Shaping epithelial lumina under pressure	20
Inorganic polyphosphate: from basic research to diagnostic and therapeutic opportunities in ALS/FTD	20
Exploring the structural dynamics of the vesicle priming machinery	20
Regulation of renal aquaporins: implications in tubular epithelial integrity	20
The role of post-translational modifications in synaptic AMPA receptor activity	20
Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt	19
Insights into the cellular consequences of LRRK2-mediated Rab protein phosphorylation	19
Revealing chromatin-specific functions of histone deacylases	19
Genome organization across scales: mechanistic insights from in vitro reconstitution studies	19
Unusual modes of cell and nuclear divisions characterise Drosophila development	19
Control of epithelial homeostasis by apical polarity: it takes a network	19
Dissecting conserved molecular mechanisms of biological toxin activity through CRISPR screening	18
Age-dependent regenerative mechanisms in the brain	18
The application of single-molecule optical tweezers to study disease-related structural dynamics in RNA	18
Molecular and structural perspectives on protein trafficking to the primary cilium membrane	18
Advances in understanding the mechanisms of the human papillomavirus oncoproteins	18
Mimetics of in-cell and subcellular crowding and solvation for protein folding	18
Understanding pyrethrin biosynthesis: toward and beyond natural pesticide overproduction	18
How do spherical bacteria regulate cell division?	18
Suppression of double-stranded RNA sensing in cancer: molecular mechanisms and therapeutic potential	17
Polycomb-mediated histone modifications and gene regulation	17
How far can omics go in unveiling the mechanisms of floral senescence?	17
Cell-free genomics: transcription factor interactions in reconstituted naïve embryonic chromatin	17
The art of hijacking: how Nsp1 impacts host gene expression during coronaviral infections	17
Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy	17
Computational approaches to understand transcription regulation in development	17
Regulation of mTORC1 by the Rag GTPases	16
The emerging theme of 3′UTR mRNA isoform regulation in reprogramming of cell metabolism	16
How intrinsically disordered regions shape the function of CREB-binding protein	16
Targeting NRF2 to promote epithelial repair	16
Eliminating oncogenic RAS: back to the future at the drawing board	16
Human E3 ubiquitin ligases: accelerators and brakes for SARS-CoV-2 infection	16
Specific isotopic labelling and reverse labelling for protein NMR spectroscopy: using metabolic precursors in sample preparation	16
Intersectin — many facets of a scaffold protein	16
Nano-organization of synaptic calcium signaling	16
Studying histone inheritance in different systems using imaging-based methods and perspectives	16
Replication associated nuclear DNA mismatch repair across kingdoms	16
Advancing our knowledge of antigen processing with computational modelling, structural biology, and immunology	16
Timely symbiosis: circadian control of legume-rhizobia symbiosis	16
Satellite cell dynamics during skeletal muscle hypertrophy	16
Bacterial microcompartments as a next-generation metabolic engineering tool: utilizing nature's solution for confining challenging catabolic pathways	16
An update on the role of sex hormones in the function of the cardiorenal mitochondria	16
Lessons from natural molecular glue degraders	16
One genome, multiple phenotypes: decoding the evolution and mechanisms of environmentally induced developmental plasticity in insects	16
A closer look at the role of deubiquitinating enzymes in the Hypoxia Inducible Factor pathway	15
Advances in utilizing reverse micelles to investigate membrane proteins	15
Nesprin-1: novel regulator of striated muscle nuclear positioning and mechanotransduction	15
Mechanisms of epithelial growth and development in the zebrafish intestine	15
Redesigning miR-34a: structural and chemical advances in the therapeutic development of an miRNA anti-cancer agent	15
Striving for sustainable biosynthesis: discovery, diversification, and production of antimicrobial drugs in Escherichia coli	15

The molecular mechanisms driving Plasmodium cell division	15
Small bites for big problems: stepwise aggregate degradation by autophagy	15
Effects of antibiotics on bacterial cell morphology and their physiological origins	15
Enhancer target prediction: state-of-the-art approaches and future prospects	15
Developing high-affinity, oxygen-insensitive [NiFe]-hydrogenases as biocatalysts for energy conversion	15
Recent advances in understanding the role of extracellular vesicles from probiotics in intestinal immunity signaling	15
Should I stay or should I go: TFIIIC as assembly factor and barrier in RNA polymerase III transcription	15
Current working models of SMC-driven DNA-loop extrusion	15
Correction: Exploring the influence of anionic lipids in the host cell membrane on viral fusion	15
Proofreading mechanisms of the innate immune receptor RIG-I: distinguishing self and viral RNA	15