Biochemical Society Transactions

Article	Citations
CD95/Fas ligand induced toxicity	113
Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques	111
Mechanisms underpinning natural variation in non-photochemical quenching kinetics	95
Solid-state nuclear magnetic resonance in the structural study of polyglutamine aggregation	86
Connecting tubules: mechanisms of endoplasmic reticulum membrane fusion	75
Translation stalling in neurons: a critical mechanism for timely protein delivery to distal cellular processes	64
Canonical and alternate mechanisms that regulate ubiquitylation by the E3 ligase parkin	61
Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling	55
The impact of amino acid metabolism on adult neurogenesis	54
Understanding immune signaling using advanced imaging techniques	52
Functions and mechanisms of eukaryotic RNA-guided programmed DNA elimination	51
Reconstituting membrane fission using a high content and throughput assay	50
Exploring the multifunctionality of SR proteins	47
Stop CRYing! Inhibition of cryptochrome function by small proteins	45
Neurodevelopmental functions of CHD8: new insights and questions	41
Caveolae and the oxidative stress response	40
Inflammatory cell death: how macrophages sense neighbouring cell infection and damage	40
Transgenic mouse models to study the physiological and pathophysiological roles of human Siglecs	39
A guide into the world of high-resolution 3D imaging: the case of soft X-ray tomography for the life sciences	39
Regulation of the antigen presentation machinery in cancer and its implication for immune surveillance	38
Negative regulation of biofilm formation by nitric oxide sensing proteins	37
Protein–protein and protein–lipid interactions of pore-forming BCL-2 family proteins in apoptosis initiation	37
Chemical catalysis by biological amyloids	37
Structural insights into ferroportin mediated iron transport	36
Do tunneling nanotubes drive chemoresistance in solid tumors and other malignancies?	35

Compatibility of termination mechanisms in bacterial transcription with inference on eukaryotic models	35
The pleiotropic roles of eIF5A in cellular life and its therapeutic potential in cancer	35
Aminoacyl-tRNA synthetase interactions in SARS-CoV-2 infection	35
Advances in understanding telomerase assembly	35
A dynamic role for transcription factors in restoring transcription through mitosis	34
Structural switching of tubulin in the microtubule lattice	34
Spo11: from topoisomerase VI to meiotic recombination initiator	34
Exploring potential developmental origins of common neurodegenerative disorders	34
Role of Yme1 in mitochondrial protein homeostasis: from regulation of protein import, OXPHOS function to lipid synthesis and mitochondrial dynamics	34
Alpha-to-beta cell trans-differentiation for treatment of diabetes	34
Maximizing the performance of protein-based fluorescent biosensors	33
Experimental systems for the analysis of mutational signatures: no ‘one-size-fits-all' solution	33
The molecular mechanisms of diapause and diapause-like reversible arrest	33
Deconstructing cancer with precision genome editing	33
The role of RHIM in necroptosis	32
Regulatory spine RS3 residue of protein kinases: a lipophilic bystander or a decisive element in the small-molecule kinase inhibitor binding?	31
The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI	31
The role of autophagy-lysosomal pathway in motor neuron diseases	31
The role of lipid scramblases in regulating lipid distributions at cellular membranes	31
Emerging roles for tumor stroma in antigen presentation and anti-cancer immunity	30
Big data and artificial intelligence (AI) methodologies for computer-aided drug design (CADD)	30
S-acylation in apoptotic and non-apoptotic cell death: a central regulator of membrane dynamics and protein function	30
Joining forces: crosstalk between mechanosensitive PIEZO1 ion channels and integrin-mediated focal adhesions	30
Encyclopaedia of eukaryotic DNA methylation: from patterns to mechanisms and functions	29
Correction: Current Working Models of SMC-driven DNA-loop extrusion	29
Structural glycobiology – from enzymes to organelles	29
Periodic pattern formation during embryonic development	28
The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder	28
The long and the short of Periscope Proteins	28
New insights into the structure and dynamics of the TOM complex in mitochondria	27
Functional characterisation of substrate-binding proteins to address nutrient uptake in marine picocyanobacteria	26
The evolution and structure/function of bHLH–PAS transcription factor family	25
The SMN-ribosome interplay: a new opportunity for Spinal Muscular Atrophy therapies	25
Studying membrane proteins with MicroED	25
Ribosomal RNA expansion segments and their role in ribosome biology	25
Transition from totipotency to pluripotency in mice: insights into molecular mechanisms	25
Last but not least: BFL-1 as an emerging target for anti-cancer therapies	25
Proteolytic regulation of mitochondrial oxidative phosphorylation components in plants	24
Frankenstein Cas9: engineering improved gene editing systems	24
Recent insights into the control of mitochondrial fission	24
Ceramide microdomains: the major influencers of the sphingolipid media platform	24
Extracellular membrane particles en route to the nucleus – exploring the VOR complex	24
Exploring cryo-electron microscopy with molecular dynamics	23
Small regulatory RNAs in rice epigenetic regulation	23
Expect the unexpected: conventional and unconventional roles for cadherins in collective cell migration	23
The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis	23
The octadecanoids: an emerging class of lipid mediators	22
Tetraspanins affect membrane structures and the trafficking of molecular partners: what impact on extracellular vesicles?	22
GCN2: roles in tumour development and progression	22
Bile acid metabolism and FXR-mediated effects in human cholestatic liver disorders	22

The role of peroxidasin in solid cancer progression	22
Three-dimensional models of the lung: past, present and future: a mini review	22
Covalent activity-based probes for imaging of serine proteases	21
Cryo-electron tomography: en route to the molecular anatomy of organisms and tissues	21
Voltage-clamp fluorometry for advancing mechanistic understanding of ion channel mechanisms with a focus on acid-sensing ion channels	21
CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact	21
Correction: Fast-forward on P-type ATPases: recent advances on structure and function	21
Molecular regulation of autophagosome formation	21
How lipids affect the energetics of co-translational alpha helical membrane protein folding	20
Mre11–Rad50: the DNA end game	20
Organismal and cellular interactions in vertebrate–alga symbioses	20
PIDD1 in cell cycle control, sterile inflammation and cell death	20
Sculpting with stiffness: rigidity as a regulator of morphogenesis	20
Structural insights into the membrane-bound proteolytic machinery of bacterial protein quality control	20
The mechanisms of alkali therapy in targeting renal diseases	19
Novel roles for G protein-coupled receptor kinases in cardiac injury and repair	19
Uncovering novel regulators of memory using C. elegans genetic and genomic analysis	19
Research progress of ZIC5 for tumor metastasis	19
Straight A’s: protein S-acylation in the activation and autophagic degradation of NOD-like receptors	19
The central role of translation elongation in response to stress	19
AAA+ proteins: one motor, multiple ways to work	19
Role of SWI/SNF chromatin remodeling genes in lung cancer development	18
General strategies for using amino acid sequence data to guide biochemical investigation of protein function	18
Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein	18
Inferiority complex: why do sensory ion channels multimerize?	18
DDX41: exploring the roles of a versatile helicase	18
Is the SPLUNC1-Orai1 axis a critical determinant of lung health?	18
Structural basis of molecular recognition among classical cadherins mediating cell adhesion	18
IMPDH dysregulation in disease: a mini review	17
Non-canonical roles of ATG8 for TFEB activation	17
Sometimes less is more: inhibitory infrared light during early reperfusion calms hyperactive mitochondria and suppresses reperfusion injury	17
Shaping epithelial lumina under pressure	17
The role of caspases as executioners of apoptosis	17
The role of post-translational modifications in synaptic AMPA receptor activity	17
S-acylation of Ca2+ transport proteins: molecular basis and functional consequences	17
The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer	17
Correction: Emerging roles for tumor stroma in antigen presentation and anti-cancer immunity	17
The influence of high-order chromatin state in the regulation of stem cell fate	17
Transcriptional control of neural stem cell activity	16
How does the tubulin code facilitate directed cell migration?	16
Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery	16
Plant supercomplex I + III2 structure and function: implications for the growing field	16
FASTK post-transcriptional regulators – a ‘FAST-tracK’ in mitochondrial gene expression	16
Transcriptional bursting: from fundamentals to novel insights	16
Folding speeds of helical membrane proteins	16
Chlamydia trachomatis invasion: a duet of effectors	16
How do spherical bacteria regulate cell division?	15
Advances in understanding the mechanisms of the human papillomavirus oncoproteins	15
Exploring the structural dynamics of the vesicle priming machinery	15
Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt	15
Insights into the cellular consequences of LRRK2-mediated Rab protein phosphorylation	15
Revealing chromatin-specific functions of histone deacylases	15
Understanding the role of ten-eleven translocation family proteins in kidney diseases	15
Control of epithelial homeostasis by apical polarity: it takes a network	15
The application of single-molecule optical tweezers to study disease-related structural dynamics in RNA	15
Genome organization across scales: mechanistic insights from in vitro reconstitution studies	15
Unusual modes of cell and nuclear divisions characterise Drosophila development	15
Inorganic polyphosphate: from basic research to diagnostic and therapeutic opportunities in ALS/FTD	15
Age-dependent regenerative mechanisms in the brain	15
An update on the role of sex hormones in the function of the cardiorenal mitochondria	14
Suppression of double-stranded RNA sensing in cancer: molecular mechanisms and therapeutic potential	14
Molecular and structural perspectives on protein trafficking to the primary cilium membrane	14
Eliminating oncogenic RAS: back to the future at the drawing board	14
Nano-organization of synaptic calcium signaling	14
Specific isotopic labelling and reverse labelling for protein NMR spectroscopy: using metabolic precursors in sample preparation	14
Lessons from natural molecular glue degraders	14
Human E3 ubiquitin ligases: accelerators and brakes for SARS-CoV-2 infection	14
The interplay of helminthic neuropeptides and proteases in parasite survival and host immunomodulation	14
The art of hijacking: how Nsp1 impacts host gene expression during coronaviral infections	14
The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation	14
Regulation of the generation of reactive oxygen species during photosynthetic electron transport	14
Studying histone inheritance in different systems using imaging-based methods and perspectives	14
Targeting NRF2 to promote epithelial repair	14
Polycomb-mediated histone modifications and gene regulation	14
Intersectin — many facets of a scaffold protein	14
Bacterial microcompartments as a next-generation metabolic engineering tool: utilizing nature's solution for confining challenging catabolic pathways	14
Npt2a as a target for treating hyperphosphatemia	14
How far can omics go in unveiling the mechanisms of floral senescence?	14
Understanding pyrethrin biosynthesis: toward and beyond natural pesticide overproduction	14
Organ-on-a-chip: current gaps and future directions	14

Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy	14
Cell-free genomics: transcription factor interactions in reconstituted naïve embryonic chromatin	14
The emerging theme of 3′UTR mRNA isoform regulation in reprogramming of cell metabolism	14
Satellite cell dynamics during skeletal muscle hypertrophy	14
Computational approaches to understand transcription regulation in development	14
Advancing our knowledge of antigen processing with computational modelling, structural biology, and immunology	14
Regulation of mTORC1 by the Rag GTPases	13
Timely symbiosis: circadian control of legume-rhizobia symbiosis	13
Recent advances in understanding the role of extracellular vesicles from probiotics in intestinal immunity signaling	13
Using genomics to understand the mechanisms of virulence and drug resistance in fungal pathogens	13
Nesprin-1: novel regulator of striated muscle nuclear positioning and mechanotransduction	13
A closer look at the role of deubiquitinating enzymes in the Hypoxia Inducible Factor pathway	13
Striving for sustainable biosynthesis: discovery, diversification, and production of antimicrobial drugs in Escherichia coli	13
Current working models of SMC-driven DNA-loop extrusion	13
Advances in utilizing reverse micelles to investigate membrane proteins	13
Microbial pathways for advanced biofuel production	13
One genome, multiple phenotypes: decoding the evolution and mechanisms of environmentally induced developmental plasticity in insects	13
GPX4: old lessons, new features	13
Should I stay or should I go: TFIIIC as assembly factor and barrier in RNA polymerase III transcription	13
Unravelling mechanisms that govern meiotic crossover formation in wheat	13
Conformational ensembles of intrinsically disordered proteins and flexible multidomain proteins	13