Biochemical Society Transactions

Article	Citations
Connecting tubules: mechanisms of endoplasmic reticulum membrane fusion	174
Structural insights into ferroportin mediated iron transport	149
CD95/Fas ligand induced toxicity	85
Translation stalling in neurons: a critical mechanism for timely protein delivery to distal cellular processes	81
Canonical and alternate mechanisms that regulate ubiquitylation by the E3 ligase parkin	68
Mechanisms underpinning natural variation in non-photochemical quenching kinetics	62
Advances in understanding telomerase assembly	62
Functions and mechanisms of eukaryotic RNA-guided programmed DNA elimination	57
Caveolae and the oxidative stress response	56
The pleiotropic roles of eIF5A in cellular life and its therapeutic potential in cancer	55
Inflammatory cell death: how macrophages sense neighbouring cell infection and damage	51
Negative regulation of biofilm formation by nitric oxide sensing proteins	46
The impact of amino acid metabolism on adult neurogenesis	45
Solid-state nuclear magnetic resonance in the structural study of polyglutamine aggregation	44
Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques	43
Chemical catalysis by biological amyloids	43
Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling	43
Reconstituting membrane fission using a high content and throughput assay	43
Do tunneling nanotubes drive chemoresistance in solid tumors and other malignancies?	41
Neurodevelopmental functions of CHD8: new insights and questions	41
Spo11: from topoisomerase VI to meiotic recombination initiator	41
Experimental systems for the analysis of mutational signatures: no ‘one-size-fits-all' solution	40
The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI	39
Maximizing the performance of protein-based fluorescent biosensors	39
Exploring potential developmental origins of common neurodegenerative disorders	39

Joining forces: crosstalk between mechanosensitive PIEZO1 ion channels and integrin-mediated focal adhesions	38
The role of autophagy-lysosomal pathway in motor neuron diseases	38
Role of Yme1 in mitochondrial protein homeostasis: from regulation of protein import, OXPHOS function to lipid synthesis and mitochondrial dynamics	38
The role of lipid scramblases in regulating lipid distributions at cellular membranes	38
Compatibility of termination mechanisms in bacterial transcription with inference on eukaryotic models	36
Structural switching of tubulin in the microtubule lattice	35
Native mass spectrometry meets X-rays for the elucidation of protein structures	35
A dynamic role for transcription factors in restoring transcription through mitosis	34
Deconstructing cancer with precision genome editing	34
Emerging roles for tumor stroma in antigen presentation and anti-cancer immunity	32
The role of RHIM in necroptosis	32
Aminoacyl-tRNA synthetase interactions in SARS-CoV-2 infection	32
The long and the short of Periscope Proteins	31
Last but not least: BFL-1 as an emerging target for anti-cancer therapies	31
The molecular mechanisms of diapause and diapause-like reversible arrest	31
Emerging concepts of reactive oxygen species functions in plants	31
Periodic pattern formation during embryonic development	31
The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder	30
The SMN-ribosome interplay: a new opportunity for Spinal Muscular Atrophy therapies	30
Transition from totipotency to pluripotency in mice: insights into molecular mechanisms	30
Correction: Current Working Models of SMC-driven DNA-loop extrusion	28
Structural glycobiology – from enzymes to organelles	27
S-acylation in apoptotic and non-apoptotic cell death: a central regulator of membrane dynamics and protein function	27
Direct or indirect: the crucial role of N-palmitate in hedgehog signaling	27
New insights into the structure and dynamics of the TOM complex in mitochondria	27
Ribosomal RNA expansion segments and their role in ribosome biology	25
G0 or no-G0: phosphatase control of quiescence and cell cycle entry	25
Heparan sulphate and neural development: dissecting the roles of astrocyte-expressed heparan sulphate	24
Sensing of double-stranded RNA in human cells: molecular mechanisms and cellular consequences	24
Expect the unexpected: conventional and unconventional roles for cadherins in collective cell migration	24
The evolution and structure/function of bHLH–PAS transcription factor family	24
A busy BOD1-y: the diverse functions of an intracellular signaling regulatory protein family	23
Frankenstein Cas9: engineering improved gene editing systems	23
Extracellular membrane particles en route to the nucleus – exploring the VOR complex	23
Ceramide microdomains: the major influencers of the sphingolipid media platform	23
The role of peroxidasin in solid cancer progression	23
The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis	23
Recent insights into the control of mitochondrial fission	23
The octadecanoids: an emerging class of lipid mediators	23
Cryo-electron tomography: en route to the molecular anatomy of organisms and tissues	23
Covalent activity-based probes for imaging of serine proteases	22
Voltage-clamp fluorometry for advancing mechanistic understanding of ion channel mechanisms with a focus on acid-sensing ion channels	22
Research progress of ZIC5 for tumor metastasis	22
Correction: Fast-forward on P-type ATPases: recent advances on structure and function	22
Tetraspanins affect membrane structures and the trafficking of molecular partners: what impact on extracellular vesicles?	22
Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein	22
Straight A’s: protein S-acylation in the activation and autophagic degradation of NOD-like receptors	22
Mre11–Rad50: the DNA end game	21
Structural insights into the membrane-bound proteolytic machinery of bacterial protein quality control	21
Advances in understanding Ton and Tol system motor proteins	21

Uncovering novel regulators of memory using C. elegans genetic and genomic analysis	21
Novel roles for G protein-coupled receptor kinases in cardiac injury and repair	21
The mechanisms of alkali therapy in targeting renal diseases	21
The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer	21
Is the SPLUNC1-Orai1 axis a critical determinant of lung health?	20
General strategies for using amino acid sequence data to guide biochemical investigation of protein function	20
Correction: Emerging roles for tumor stroma in antigen presentation and anti-cancer immunity	20
The role of post-translational modifications in synaptic AMPA receptor activity	20
DDX41: exploring the roles of a versatile helicase	20
The central role of translation elongation in response to stress	20
Sculpting with stiffness: rigidity as a regulator of morphogenesis	20
Regulation of renal aquaporins: implications in tubular epithelial integrity	20
Structural basis of molecular recognition among classical cadherins mediating cell adhesion	20
How does the tubulin code facilitate directed cell migration?	20
Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery	20
The influence of high-order chromatin state in the regulation of stem cell fate	20
Chlamydia trachomatis invasion: a duet of effectors	19
Plant supercomplex I + III2 structure and function: implications for the growing field	19
S-acylation of Ca2+ transport proteins: molecular basis and functional consequences	19
Exploring the structural dynamics of the vesicle priming machinery	19
Folding speeds of helical membrane proteins	19
Transcriptional bursting: from fundamentals to novel insights	19
Transcriptional control of neural stem cell activity	19
Understanding the role of ten-eleven translocation family proteins in kidney diseases	19
Inorganic polyphosphate: from basic research to diagnostic and therapeutic opportunities in ALS/FTD	19
Sometimes less is more: inhibitory infrared light during early reperfusion calms hyperactive mitochondria and suppresses reperfusion injury	19
FASTK post-transcriptional regulators – a ‘FAST-tracK’ in mitochondrial gene expression	19
Shaping epithelial lumina under pressure	19
Designing de novo TIM barrels: insights into stabilization, diversification, and functionalization strategies	19
Suppression of double-stranded RNA sensing in cancer: molecular mechanisms and therapeutic potential	18
Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt	18
Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy	18
How do spherical bacteria regulate cell division?	18
Unusual modes of cell and nuclear divisions characterise Drosophila development	18
Age-dependent regenerative mechanisms in the brain	18
Revealing chromatin-specific functions of histone deacylases	18
Insights into the cellular consequences of LRRK2-mediated Rab protein phosphorylation	17
Mimetics of in-cell and subcellular crowding and solvation for protein folding	17
Advances in understanding the mechanisms of the human papillomavirus oncoproteins	17
Targeting NRF2 to promote epithelial repair	17
The art of hijacking: how Nsp1 impacts host gene expression during coronaviral infections	17
Control of epithelial homeostasis by apical polarity: it takes a network	17
Molecular and structural perspectives on protein trafficking to the primary cilium membrane	17
Understanding pyrethrin biosynthesis: toward and beyond natural pesticide overproduction	17
Regulation of mTORC1 by the Rag GTPases	17
Genome organization across scales: mechanistic insights from in vitro reconstitution studies	17
The application of single-molecule optical tweezers to study disease-related structural dynamics in RNA	17
Dissecting conserved molecular mechanisms of biological toxin activity through CRISPR screening	17
How far can omics go in unveiling the mechanisms of floral senescence?	17
An update on the role of sex hormones in the function of the cardiorenal mitochondria	16
Computational approaches to understand transcription regulation in development	16
Timely symbiosis: circadian control of legume-rhizobia symbiosis	16
Studying histone inheritance in different systems using imaging-based methods and perspectives	16
Human E3 ubiquitin ligases: accelerators and brakes for SARS-CoV-2 infection	16
Nano-organization of synaptic calcium signaling	16
One genome, multiple phenotypes: decoding the evolution and mechanisms of environmentally induced developmental plasticity in insects	16
Eliminating oncogenic RAS: back to the future at the drawing board	16
Lessons from natural molecular glue degraders	16
Polycomb-mediated histone modifications and gene regulation	15
Advancing our knowledge of antigen processing with computational modelling, structural biology, and immunology	15
Specific isotopic labelling and reverse labelling for protein NMR spectroscopy: using metabolic precursors in sample preparation	15
Should I stay or should I go: TFIIIC as assembly factor and barrier in RNA polymerase III transcription	15
Current working models of SMC-driven DNA-loop extrusion	15
Effects of antibiotics on bacterial cell morphology and their physiological origins	15
Advances in utilizing reverse micelles to investigate membrane proteins	15
The emerging theme of 3′UTR mRNA isoform regulation in reprogramming of cell metabolism	15
Intersectin — many facets of a scaffold protein	15
Bacterial microcompartments as a next-generation metabolic engineering tool: utilizing nature's solution for confining challenging catabolic pathways	15
Satellite cell dynamics during skeletal muscle hypertrophy	15
Unravelling mechanisms that govern meiotic crossover formation in wheat	15
The molecular mechanisms driving Plasmodium cell division	15
Nesprin-1: novel regulator of striated muscle nuclear positioning and mechanotransduction	15
GPX4: old lessons, new features	15
Cell-free genomics: transcription factor interactions in reconstituted naïve embryonic chromatin	15
Striving for sustainable biosynthesis: discovery, diversification, and production of antimicrobial drugs in Escherichia coli	15
How intrinsically disordered regions shape the function of CREB-binding protein	15
A closer look at the role of deubiquitinating enzymes in the Hypoxia Inducible Factor pathway	15
Recent advances in understanding the role of extracellular vesicles from probiotics in intestinal immunity signaling	15
Mechanisms of epithelial growth and development in the zebrafish intestine	15
Correction: Exploring the influence of anionic lipids in the host cell membrane on viral fusion	14

Differential functions of the KRAS splice variants	14
Redesigning miR-34a: structural and chemical advances in the therapeutic development of an miRNA anti-cancer agent	14
Using genomics to understand the mechanisms of virulence and drug resistance in fungal pathogens	14
DIG-DUBs: mechanisms and functions of ISG15 deconjugation by human and viral cross-reactive ubiquitin proteases	14
Strength in numbers: effect of protein crowding on the shape of cell membranes	14
Enhancer target prediction: state-of-the-art approaches and future prospects	14
The remodeling of Z-DNA in the mammalian germ line	13
How do different cell populations orchestrate myelin regeneration?	13
Quaternary arrangements of membrane proteins: an aquaporin case	13
Effectors and effects of arginine methylation	13
CRISPRi: a way to integrate iPSC-derived neuronal models	13
Atomic force microscopy 3D structural reconstruction of individual particles in the study of amyloid protein assemblies	13
Viral subversion of the cell polarity regulator Scribble	13
SUMO and the DNA damage response	13
The molecular mechanisms of human separase regulation	13
Developing high-affinity, oxygen-insensitive [NiFe]-hydrogenases as biocatalysts for energy conversion	13
Proofreading mechanisms of the innate immune receptor RIG-I: distinguishing self and viral RNA	13
Current understanding of heparanase 2 regulation, a non-heparanase	13
Mapping lipid pathways during phagocytosis	13
Endothelial Neuropilin-1: a multifaced signal transducer with an emerging role in inflammation and atherosclerosis beyond angiogenesis	13
Modification of extracellular matrix proteins by oxidants and electrophiles	13
Dopamine synthesis and transport: current and novel therapeutics for parkinsonisms	12
Interactions between zinc and NRF2 in vascular redox signalling	12
Beyond expectations: the development and biological activity of cytokinin oxidase/dehydrogenase inhibitors	12
Engineering CRISPR guide RNAs for programmable RNA sensors	12
Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT	12
Deubiquitinases in muscle physiology and disorders	12
The role of PQBP1 in neural development and function	12
NLR immune receptors: structure and function in plant disease resistance	12
Scaffolds and the scaffolding domain: an alternative paradigm for caveolin-1 signaling	12
DNA translocation by the CMG helicase: the helical inchworm model	12
The NMDAR-BK channelosomes as regulators of synaptic plasticity	12
The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation	12
Regulation of cardiomyocyte intracellular trafficking and signal transduction by protein palmitoylation	12
The molecular mechanisms of the bacterial iron sensor IdeR	12
Progress in recapitulating morphogenesis of blood microvascular structures for microphysiological systems development	12
Technology to the rescue: how to uncover the role of transposable elements in preimplantation development	12
Molecular regulators of chemotaxis in human hematopoietic stem cells	11
SMC-based immunity against extrachromosomal DNA elements	11
Lipid transport mechanisms in human ABCA family transporters: a structural perspective	11
Phase separation and viral factories: unveiling the physical processes supporting RNA packaging in dsRNA viruses	11
The cellular dynamics of neural tube formation	11
ESCRTing the RABs through conversion	11
ATP binding to Nerve Growth Factor (NGF) and pro-Nerve Growth Factor (proNGF): an endogenous molecular switch modulating neurotrophins activity	11
Regulation of ATR–CHK1 signaling by ubiquitination of CLASPIN	11
Exploring microRNAs in craniofacial regenerative medicine	11
Single-molecule study of the dynamics of the molecular chaperone Hsp70 during the functional cycle	11
Towards a phylogenetically informed approach to solving protein–protein interactions	11
Advances in nanobody multimerization and multispecificity: from in vivo assembly to in vitro production	11
A multi-dimensional view of context-dependent G protein-coupled receptor function	11
Is bRaQCing bad? New roles for ribosome associated quality control factors in stress granule regulation	11
Beyond the mono-nucleosome	11
Kinetochore–microtubule error correction for biorientation: lessons from yeast	11
Post-translational regulation of the low-density lipoprotein receptor provides new targets for cholesterol regulation	11
Force writes memory: proline isomerization as a molecular memory switch	11
What voltage-sensing phosphatases can reveal about the mechanisms of ion channel regulation by phosphoinositides	11
Insights into mechanisms of ubiquitin ADP-ribosylation reversal	11
ALTercations at telomeres: stress, recombination and extrachromosomal affairs	10
The mRNA dynamics underpinning translational control mechanisms of Drosophila melanogaster oogenesis	10
Advances in mechanochemical modelling of vertebrate gastrulation	10
Morphogenesis of leaves: from initiation to the production of diverse shapes	10
The functional importance of bacterial oxidative phosphonate pathways	10
Therapeutic targeting of eukaryotic initiation factor (eIF) 4E	10
Discovery of telomerase inhibitors: existing strategies and emerging innovations	10
Therapeutic targeting of TRAIL death receptors	10
Histone mutations in cancer	10
The SWI/SNF ATP-dependent chromatin remodeling complex in cell lineage priming and early development	10
Computational modelling of aggressive B-cell lymphoma	10
Processing DNA lesions during mitosis to prevent genomic instability	10
Cytoophidia and filaments: you must unlearn what you have learned	10
The interactions of amyloid β aggregates with phospholipid membranes and the implications for neurodegeneration	10
The emerging role of Rab proteins in osteoclast organelle biogenesis and function	10
Activation is only the beginning: mechanisms that tune kinase substrate specificity	10
The stabilization of Arp2/3 complex generated actin filaments	10
Cytokinin and reproductive shoot architecture: bigger and better?	10
CYRI proteins: controllers of actin dynamics in the cellular ‘eat vs walk’ decision	10
Nuclear RNA: a transcription-dependent regulator of chromatin structure	10
Mitochondrial DNA as inflammatory DAMP: a warning of an aging immune system?	10
Emerging liquid biopsy tools to analyse cancer biomarkers: electrochemical sensors and extracellular vesicle analysis	10
New insights into the mechanochemical coupling mechanism of kinesin–microtubule complexes from their high-resolution structures	10
Allosteric regulation and inhibition of protein kinases	10
Protective HLA-B57: T cell and natural killer cell recognition in HIV infection	10
CRAC channels and patho-physiology of peripheral organ systems	9
Mechanisms conferring bacterial cell wall variability and adaptivity	9
Advances in polarised luminescence approaches to understanding interactions between biomolecules	9
The O-GlcNAc cycling in neurodevelopment and associated diseases	9
Molecular aspects of Interleukin-36 cytokine activation and regulation	9
Rho GTPases in cancer resistance: mechanisms, vulnerabilities, and therapeutic opportunities	9
The multifunctional role of intrinsic disorder in NF-κB signaling	9
Emerging drivers of DNA repeat expansions	9
Recent advances in the structure and activation mechanisms of metabolite-releasing Pannexin 1 channels	9
Membrane protein structure and dynamics probed by MicroED	9
The role of HNF4α in adenocarcinoma	9
The role of lipids in genome integrity and pluripotency	9
Using modified mRNA for cardiomyocyte proliferation and cardiac genetic disease modelling and treatment	9