Biochemical Society Transactions

Article	Citations
Caveolae and the oxidative stress response	95
CD95/Fas ligand induced toxicity	95
Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques	90
Organ-on-chip applications in drug discovery: an end user perspective	83
Functions and mechanisms of eukaryotic RNA-guided programmed DNA elimination	77
Reconstituting membrane fission using a high content and throughput assay	75
Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling	72
Chemical catalysis by biological amyloids	70
Negative regulation of biofilm formation by nitric oxide sensing proteins	55
Do tunneling nanotubes drive chemoresistance in solid tumors and other malignancies?	49
Inflammatory cell death: how macrophages sense neighbouring cell infection and damage	48
Protein–protein and protein–lipid interactions of pore-forming BCL-2 family proteins in apoptosis initiation	46
Structural insights into ferroportin mediated iron transport	45
Advances in understanding telomerase assembly	43
A guide into the world of high-resolution 3D imaging: the case of soft X-ray tomography for the life sciences	42
Neurodevelopmental functions of CHD8: new insights and questions	37
Understanding immune signaling using advanced imaging techniques	36
Connecting tubules: mechanisms of endoplasmic reticulum membrane fusion	36
Stop CRYing! Inhibition of cryptochrome function by small proteins	36
Transgenic mouse models to study the physiological and pathophysiological roles of human Siglecs	35
The impact of amino acid metabolism on adult neurogenesis	34
Exploring the multifunctionality of SR proteins	34
Solid-state nuclear magnetic resonance in the structural study of polyglutamine aggregation	33
Maximizing the performance of protein-based fluorescent biosensors	33
Regulation of the antigen presentation machinery in cancer and its implication for immune surveillance	33

The pleiotropic roles of eIF5A in cellular life and its therapeutic potential in cancer	33
The role of lipid scramblases in regulating lipid distributions at cellular membranes	32
Structural switching of tubulin in the microtubule lattice	32
LARP6 proteins in plants	32
The role of protein acetylation in regulating mitochondrial fusion and fission	32
The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI	32
Exploring potential developmental origins of common neurodegenerative disorders	31
Aminoacyl-tRNA synthetase interactions in SARS-CoV-2 infection	31
Regulatory spine RS3 residue of protein kinases: a lipophilic bystander or a decisive element in the small-molecule kinase inhibitor binding?	31
Experimental systems for the analysis of mutational signatures: no ‘one-size-fits-all' solution	30
Deconstructing cancer with precision genome editing	29
Role of Yme1 in mitochondrial protein homeostasis: from regulation of protein import, OXPHOS function to lipid synthesis and mitochondrial dynamics	29
Applications of Cryo-EM in small molecule and biologics drug design	29
Spo11: from topoisomerase VI to meiotic recombination initiator	29
Writing and erasing O-GlcNAc from target proteins in cells	29
Compatibility of termination mechanisms in bacterial transcription with inference on eukaryotic models	29
The role of autophagy-lysosomal pathway in motor neuron diseases	28
Alpha-to-beta cell trans-differentiation for treatment of diabetes	28
Joining forces: crosstalk between mechanosensitive PIEZO1 ion channels and integrin-mediated focal adhesions	28
A dynamic role for transcription factors in restoring transcription through mitosis	28
Emerging roles for tumor stroma in antigen presentation and anti-cancer immunity	28
Big data and artificial intelligence (AI) methodologies for computer-aided drug design (CADD)	27
The role of RHIM in necroptosis	27
Microglia extracellular vesicles: focus on molecular composition and biological function	27
The molecular mechanisms of diapause and diapause-like reversible arrest	27
Correction: Current Working Models of SMC-driven DNA-loop extrusion	27
S-acylation in apoptotic and non-apoptotic cell death: a central regulator of membrane dynamics and protein function	26
Conquer by cryo-EM without physically dividing	26
Are cachexia-associated tumors transmitTERS of ER stress?	26
Studying membrane proteins with MicroED	26
Functional characterisation of substrate-binding proteins to address nutrient uptake in marine picocyanobacteria	26
Transition from totipotency to pluripotency in mice: insights into molecular mechanisms	26
Last but not least: BFL-1 as an emerging target for anti-cancer therapies	25
Ribosomal RNA expansion segments and their role in ribosome biology	24
New insights into the structure and dynamics of the TOM complex in mitochondria	24
Proteolytic regulation of mitochondrial oxidative phosphorylation components in plants	24
The SMN-ribosome interplay: a new opportunity for Spinal Muscular Atrophy therapies	24
Structural glycobiology – from enzymes to organelles	23
CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact	23
Efficiency and equity in origin licensing to ensure complete DNA replication	23
Encyclopaedia of eukaryotic DNA methylation: from patterns to mechanisms and functions	23
The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder	23
The evolution and structure/function of bHLH–PAS transcription factor family	23
Periodic pattern formation during embryonic development	23
Ceramide microdomains: the major influencers of the sphingolipid media platform	23
The long and the short of Periscope Proteins	23
Frankenstein Cas9: engineering improved gene editing systems	22
Recent insights into the control of mitochondrial fission	21
Exploring cryo-electron microscopy with molecular dynamics	21
Bile acid metabolism and FXR-mediated effects in human cholestatic liver disorders	21

Small regulatory RNAs in rice epigenetic regulation	21
The role of peroxidasin in solid cancer progression	21
How neural stem cells contribute to neocortex development	21
Extracellular membrane particles en route to the nucleus – exploring the VOR complex	21
Cryo-electron tomography: en route to the molecular anatomy of organisms and tissues	21
The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis	21
MsbA: an ABC transporter paradigm	21
The octadecanoids: an emerging class of lipid mediators	20
How lipids affect the energetics of co-translational alpha helical membrane protein folding	20
Molecular regulation of autophagosome formation	20
Chemical biology approaches to study histone interactors	20
Expect the unexpected: conventional and unconventional roles for cadherins in collective cell migration	20
GCN2: roles in tumour development and progression	20
Tetraspanins affect membrane structures and the trafficking of molecular partners: what impact on extracellular vesicles?	20
Three-dimensional models of the lung: past, present and future: a mini review	20
The central role of translation elongation in response to stress	19
Uncovering novel regulators of memory using C. elegans genetic and genomic analysis	19
Sculpting with stiffness: rigidity as a regulator of morphogenesis	19
Voltage-clamp fluorometry for advancing mechanistic understanding of ion channel mechanisms with a focus on acid-sensing ion channels	19
Mechanisms of vascular smooth muscle cell investment and phenotypic diversification in vascular diseases	19
Inferiority complex: why do sensory ion channels multimerize?	19
Structural basis of molecular recognition among classical cadherins mediating cell adhesion	18
Correction: Fast-forward on P-type ATPases: recent advances on structure and function	18
AAA+ proteins: one motor, multiple ways to work	18
Mre11–Rad50: the DNA end game	18
Covalent activity-based probes for imaging of serine proteases	18
Is the SPLUNC1-Orai1 axis a critical determinant of lung health?	18
The role of caspases as executioners of apoptosis	18
General strategies for using amino acid sequence data to guide biochemical investigation of protein function	18
Role of SWI/SNF chromatin remodeling genes in lung cancer development	18
PIDD1 in cell cycle control, sterile inflammation and cell death	17
The mechanisms of alkali therapy in targeting renal diseases	17
Novel roles for G protein-coupled receptor kinases in cardiac injury and repair	17
Structural insights into the membrane-bound proteolytic machinery of bacterial protein quality control	17
Research progress of ZIC5 for tumor metastasis	17
Straight A’s: protein acylation in the S-acylation and autophagic degradation of NOD-like receptors	17
DDX41: exploring the roles of a versatile helicase	17
IMPDH dysregulation in disease: a mini review	17
Ion channels as convergence points in the pathology of pulmonary arterial hypertension	17
The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer	17
Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery	16
Improving photosynthesis through the enhancement of Rubisco carboxylation capacity	16
Transcriptional control of neural stem cell activity	16
Non-canonical roles of ATG8 for TFEB activation	16
Understanding the role of ten-eleven translocation family proteins in kidney diseases	16
Organismal and cellular interactions in vertebrate–alga symbioses	16
Correction: Emerging roles for tumor stroma in antigen presentation and anti-cancer immunity	16
Artificial protein assemblies with well-defined supramolecular protein nanostructures	16
Plant supercomplex I + III2 structure and function: implications for the growing field	16
Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein	16
The influence of high-order chromatin state in the regulation of stem cell fate	16
The role of pro-domains in human growth factors and cytokines	16
Shaping epithelial lumina under pressure	16
Folding speeds of helical membrane proteins	15
S-acylation of Ca2+ transport proteins: molecular basis and functional consequences	15
How does the tubulin code facilitate directed cell migration?	15
Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt	15
Genome organization across scales: mechanistic insights from in vitro reconstitution studies	15
Chlamydia trachomatis invasion: a duet of effectors	15
Exploring the structural dynamics of the vesicle priming machinery	15
Inorganic polyphosphate: from basic research to diagnostic and therapeutic opportunities in ALS/FTD	15
Unusual modes of cell and nuclear divisions characterise Drosophila development	15
Insights into the cellular consequences of LRRK2-mediated Rab protein phosphorylation	15
Structural and functional approaches to studying cAMP regulation of HCN channels	15
The role of post-translational modifications in synaptic AMPA receptor activity	15
Sometimes less is more: inhibitory infrared light during early reperfusion calms hyperactive mitochondria and suppresses reperfusion injury	15
The application of single-molecule optical tweezers to study disease-related structural dynamics in RNA	15
Transcriptional bursting: from fundamentals to novel insights	15
Organ-on-a-chip: current gaps and future directions	14
Advances in understanding the mechanisms of the human papillomavirus oncoproteins	14
Age-dependent regenerative mechanisms in the brain	14
Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy	14
Revealing chromatin-specific functions of histone deacylases	14
U7 deciphered: the mechanism that forms the unusual 3′ end of metazoan replication-dependent histone mRNAs	14
Solid state NMR of membrane proteins: methods and applications	14
Regulation of the generation of reactive oxygen species during photosynthetic electron transport	14
LRRK2 along the Golgi and lysosome connection: a jamming situation	14
Understanding pyrethrin biosynthesis: toward and beyond natural pesticide overproduction	14
Suppression of double-stranded RNA sensing in cancer: molecular mechanisms and therapeutic potential	14
Molecular and structural perspectives on protein trafficking to the primary cilium membrane	14

Cell-free genomics: transcription factor interactions in reconstituted naïve embryonic chromatin	13
Lessons from natural molecular glue degraders	13
Npt2a as a target for treating hyperphosphatemia	13
Timely symbiosis: circadian control of legume-rhizobia symbiosis	13
The art of hijacking: how Nsp1 impacts host gene expression during coronaviral infections	13
Human E3 ubiquitin ligases: accelerators and brakes for SARS-CoV-2 infection	13
How far can omics go in unveiling the mechanisms of floral senescence?	13
Bioengineering silk into blood vessels	13
The interplay of helminthic neuropeptides and proteases in parasite survival and host immunomodulation	13
How do spherical bacteria regulate cell division?	13
An update on the role of sex hormones in the function of the cardiorenal mitochondria	13
Studying histone inheritance in different systems using imaging-based methods and perspectives	13
Advancing our knowledge of antigen processing with computational modelling, structural biology, and immunology	13
Specific isotopic labelling and reverse labelling for protein NMR spectroscopy: using metabolic precursors in sample preparation	12
GPX4: old lessons, new features	12
Targeting NRF2 to promote epithelial repair	12
Regulation of mTORC1 by the Rag GTPases	12
The NEDD4 ubiquitin E3 ligase: a snapshot view of its functional activity and regulation	12
Intersectin — many facets of a scaffold protein	12
Polycomb-mediated histone modifications and gene regulation	12
Lipid–protein interactions in virus assembly and budding from the host cell plasma membrane	12
Bacterial microcompartments as a next-generation metabolic engineering tool: utilizing nature's solution for confining challenging catabolic pathways	12
One genome, multiple phenotypes: decoding the evolution and mechanisms of environmentally induced developmental plasticity in insects	12
Eliminating oncogenic RAS: back to the future at the drawing board	12
Nano-organization of synaptic calcium signaling	12
The emerging theme of 3′UTR mRNA isoform regulation in reprogramming of cell metabolism	12
A closer look at the role of deubiquitinating enzymes in the Hypoxia Inducible Factor pathway	12
Satellite cell dynamics during skeletal muscle hypertrophy	12
Computational approaches to understand transcription regulation in development	12
How do different cell populations orchestrate myelin regeneration?	11
Strength in numbers: effect of protein crowding on the shape of cell membranes	11
To export, or not to export: how nuclear export factor variants resolve Piwi's dilemma	11
Current working models of SMC-driven DNA-loop extrusion	11
Mechanisms of catalytic RNA molecules	11
Nesprin-1: novel regulator of striated muscle nuclear positioning and mechanotransduction	11
Unravelling mechanisms that govern meiotic crossover formation in wheat	11
The molecular mechanisms driving Plasmodium cell division	11
The remodeling of Z-DNA in the mammalian germ line	11
Atomic force microscopy 3D structural reconstruction of individual particles in the study of amyloid protein assemblies	11
The molecular mechanisms of human separase regulation	11
Modification of extracellular matrix proteins by oxidants and electrophiles	11
Conformational ensembles of intrinsically disordered proteins and flexible multidomain proteins	11
Mechanisms of epithelial growth and development in the zebrafish intestine	11
Using genomics to understand the mechanisms of virulence and drug resistance in fungal pathogens	11
Microbial pathways for advanced biofuel production	11
Striving for sustainable biosynthesis: discovery, diversification, and production of antimicrobial drugs in Escherichia coli	11
Current understanding of heparanase 2 regulation, a non-heparanase	11
Endothelial Neuropilin-1: a multifaced signal transducer with an emerging role in inflammation and atherosclerosis beyond angiogenesis	11
Enhancer target prediction: state-of-the-art approaches and future prospects	11
NLR immune receptors: structure and function in plant disease resistance	11
Advances in utilizing reverse micelles to investigate membrane proteins	11
Recent advances in understanding the role of extracellular vesicles from probiotics in intestinal immunity signaling	11
Targeting the BCL-2-regulated apoptotic pathway for the treatment of solid cancers	11
Effects of antibiotics on bacterial cell morphology and their physiological origins	11
Correction: Exploring the influence of anionic lipids in the host cell membrane on viral fusion	11
Proofreading mechanisms of the innate immune receptor RIG-I: distinguishing self and viral RNA	10
Whole-genome methods to define DNA and histone accessibility and long-range interactions in chromatin	10
Regulation of cardiomyocyte intracellular trafficking and signal transduction by protein palmitoylation	10
The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation	10
Scaffolds and the scaffolding domain: an alternative paradigm for caveolin-1 signaling	10
SUMO and the DNA damage response	10
Quaternary arrangements of membrane proteins: an aquaporin case	10
Mapping lipid pathways during phagocytosis	10
Decoding the sorghum methylome: understanding epigenetic contributions to agronomic traits	10
Dopamine synthesis and transport: current and novel therapeutics for parkinsonisms	10
Interactions between zinc and NRF2 in vascular redox signalling	10
Deubiquitinases in muscle physiology and disorders	10
Beyond expectations: the development and biological activity of cytokinin oxidase/dehydrogenase inhibitors	10
Effectors and effects of arginine methylation	10
Cofactor F420, an emerging redox power in biosynthesis of secondary metabolites	10
Directed evolution approaches for optogenetic tool development	10
Viral subversion of the cell polarity regulator Scribble	10
DIG-DUBs: mechanisms and functions of ISG15 deconjugation by human and viral cross-reactive ubiquitin proteases	10
New appreciation for an old pathway: the Lands Cycle moves into new arenas in health and disease	10
Live-cell visualization of cytochrome c: a tool to explore apoptosis	10
The role of PQBP1 in neural development and function	10
Engineering CRISPR guide RNAs for programmable RNA sensors	10
Developing high-affinity, oxygen-insensitive [NiFe]-hydrogenases as biocatalysts for energy conversion	10
CRISPRi: a way to integrate iPSC-derived neuronal models	10
Differential functions of the KRAS splice variants	10
Single-molecule study of the dynamics of the molecular chaperone Hsp70 during the functional cycle	9
Engineering E. coli to synthesize butanol	9
SMC-based immunity against extrachromosomal DNA elements	9
Computational exploration of cellular communication in skin from emerging single-cell and spatial transcriptomic data	9
Phase separation and viral factories: unveiling the physical processes supporting RNA packaging in dsRNA viruses	9
Advances in nanobody multimerization and multispecificity: from in vivo assembly to in vitro production	9
The cellular dynamics of neural tube formation	9
The molecular mechanisms of the bacterial iron sensor IdeR	9
Semi- and fully synthetic carbohydrate vaccines against pathogenic bacteria: recent developments	9
Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT	9
Epigenetic mechanisms in paediatric brain tumours: regulators lose control	9
Beyond the mono-nucleosome	9
A multi-dimensional view of context-dependent G protein-coupled receptor function	9
Integration of functional genomics data to uncover cell type-specific pathways affected in Parkinson's disease	9
Structure determination of GPCRs: cryo-EM compared with X-ray crystallography	9