Biochemical Society Transactions

Article	Citations
The pleiotropic roles of eIF5A in cellular life and its therapeutic potential in cancer	166
Illuminating membrane structural dynamics of fusion and endocytosis with advanced light imaging techniques	142
Reconstituting membrane fission using a high content and throughput assay	85
Chemical catalysis by biological amyloids	78
Neurodevelopmental functions of CHD8: new insights and questions	62
Protein–protein and protein–lipid interactions of pore-forming BCL-2 family proteins in apoptosis initiation	61
Connecting tubules: mechanisms of endoplasmic reticulum membrane fusion	59
Regulation of germline proteostasis by HSF1 and insulin/IGF-1 signaling	55
Structural insights into ferroportin mediated iron transport	53
CD95/Fas ligand induced toxicity	52
Solid-state nuclear magnetic resonance in the structural study of polyglutamine aggregation	48
Inflammatory cell death: how macrophages sense neighbouring cell infection and damage	44
Negative regulation of biofilm formation by nitric oxide sensing proteins	43
Caveolae and the oxidative stress response	43
Translation stalling in neurons: a critical mechanism for timely protein delivery to distal cellular processes	42
Canonical and alternate mechanisms that regulate ubiquitylation by the E3 ligase parkin	42
Do tunneling nanotubes drive chemoresistance in solid tumors and other malignancies?	41
Advances in understanding telomerase assembly	41
Mechanisms underpinning natural variation in non-photochemical quenching kinetics	41
The impact of amino acid metabolism on adult neurogenesis	41
Spo11: from topoisomerase VI to meiotic recombination initiator	39
Aminoacyl-tRNA synthetase interactions in SARS-CoV-2 infection	39
Functions and mechanisms of eukaryotic RNA-guided programmed DNA elimination	39
A dynamic role for transcription factors in restoring transcription through mitosis	38
Exploring potential developmental origins of common neurodegenerative disorders	38

The molecular mechanisms of diapause and diapause-like reversible arrest	38
Emerging roles for tumor stroma in antigen presentation and anti-cancer immunity	38
Joining forces: crosstalk between mechanosensitive PIEZO1 ion channels and integrin-mediated focal adhesions	37
Maximizing the performance of protein-based fluorescent biosensors	37
The role of filamentation in activation and DNA sequence specificity of the sequence-specific endonuclease SgrAI	37
The role of lipid scramblases in regulating lipid distributions at cellular membranes	35
Structural switching of tubulin in the microtubule lattice	35
Deconstructing cancer with precision genome editing	35
Experimental systems for the analysis of mutational signatures: no ‘one-size-fits-all' solution	33
Role of Yme1 in mitochondrial protein homeostasis: from regulation of protein import, OXPHOS function to lipid synthesis and mitochondrial dynamics	32
The role of RHIM in necroptosis	31
Proteolytic regulation of mitochondrial oxidative phosphorylation components in plants	31
The role of autophagy-lysosomal pathway in motor neuron diseases	31
Transition from totipotency to pluripotency in mice: insights into molecular mechanisms	31
Compatibility of termination mechanisms in bacterial transcription with inference on eukaryotic models	31
Encyclopaedia of eukaryotic DNA methylation: from patterns to mechanisms and functions	31
Sensing of double-stranded RNA in human cells: molecular mechanisms and cellular consequences	30
Correction: Current Working Models of SMC-driven DNA-loop extrusion	29
Structural glycobiology – from enzymes to organelles	29
The long and the short of Periscope Proteins	28
Periodic pattern formation during embryonic development	27
Last but not least: BFL-1 as an emerging target for anti-cancer therapies	27
The TFIIS N-terminal domain (TND): a transcription assembly module at the interface of order and disorder	26
The evolution and structure/function of bHLH–PAS transcription factor family	26
S-acylation in apoptotic and non-apoptotic cell death: a central regulator of membrane dynamics and protein function	26
The SMN-ribosome interplay: a new opportunity for Spinal Muscular Atrophy therapies	26
New insights into the structure and dynamics of the TOM complex in mitochondria	25
Frankenstein Cas9: engineering improved gene editing systems	24
Emerging concepts of reactive oxygen species functions in plants	24
Expect the unexpected: conventional and unconventional roles for cadherins in collective cell migration	24
Ribosomal RNA expansion segments and their role in ribosome biology	24
A busy BOD1-y: the diverse functions of an intracellular signaling regulatory protein family	23
The octadecanoids: an emerging class of lipid mediators	23
The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis	23
Extracellular membrane particles en route to the nucleus – exploring the VOR complex	23
Heparan sulphate and neural development: dissecting the roles of astrocyte-expressed heparan sulphate	23
Recent insights into the control of mitochondrial fission	22
CRISPR/Cas9 and genetic screens in malaria parasites: small genomes, big impact	22
Voltage-clamp fluorometry for advancing mechanistic understanding of ion channel mechanisms with a focus on acid-sensing ion channels	22
Cryo-electron tomography: en route to the molecular anatomy of organisms and tissues	22
The role of peroxidasin in solid cancer progression	22
Small regulatory RNAs in rice epigenetic regulation	22
Tetraspanins affect membrane structures and the trafficking of molecular partners: what impact on extracellular vesicles?	22
Ceramide microdomains: the major influencers of the sphingolipid media platform	22
Advances in understanding Ton and Tol system motor proteins	21
Straight A’s: protein S-acylation in the activation and autophagic degradation of NOD-like receptors	21
The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer	21
Correction: Fast-forward on P-type ATPases: recent advances on structure and function	21
Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein	20
Covalent activity-based probes for imaging of serine proteases	20

Research progress of ZIC5 for tumor metastasis	20
Structural basis of molecular recognition among classical cadherins mediating cell adhesion	20
The central role of translation elongation in response to stress	20
Structural insights into the membrane-bound proteolytic machinery of bacterial protein quality control	20
Role of SWI/SNF chromatin remodeling genes in lung cancer development	20
General strategies for using amino acid sequence data to guide biochemical investigation of protein function	20
The mechanisms of alkali therapy in targeting renal diseases	20
Sculpting with stiffness: rigidity as a regulator of morphogenesis	20
Uncovering novel regulators of memory using C. elegans genetic and genomic analysis	20
Novel roles for G protein-coupled receptor kinases in cardiac injury and repair	20
Mre11–Rad50: the DNA end game	20
Is the SPLUNC1-Orai1 axis a critical determinant of lung health?	20
DDX41: exploring the roles of a versatile helicase	19
Transcriptional control of neural stem cell activity	19
Regulation of renal aquaporins: implications in tubular epithelial integrity	19
How does the tubulin code facilitate directed cell migration?	19
The role of post-translational modifications in synaptic AMPA receptor activity	19
Plant supercomplex I + III2 structure and function: implications for the growing field	19
The influence of high-order chromatin state in the regulation of stem cell fate	19
FASTK post-transcriptional regulators – a ‘FAST-tracK’ in mitochondrial gene expression	19
Chlamydia trachomatis invasion: a duet of effectors	19
S-acylation of Ca2+ transport proteins: molecular basis and functional consequences	19
Understanding the role of ten-eleven translocation family proteins in kidney diseases	18
Targeting trypanosomes: how chemogenomics and artificial intelligence can guide drug discovery	18
Designing de novo TIM barrels: insights into stabilization, diversification, and functionalization strategies	18
Sometimes less is more: inhibitory infrared light during early reperfusion calms hyperactive mitochondria and suppresses reperfusion injury	18
Exploring the structural dynamics of the vesicle priming machinery	18
Transcriptional bursting: from fundamentals to novel insights	18
Correction: Emerging roles for tumor stroma in antigen presentation and anti-cancer immunity	18
Shaping epithelial lumina under pressure	18
Inorganic polyphosphate: from basic research to diagnostic and therapeutic opportunities in ALS/FTD	18
Unusual modes of cell and nuclear divisions characterise Drosophila development	17
Revealing chromatin-specific functions of histone deacylases	17
The application of single-molecule optical tweezers to study disease-related structural dynamics in RNA	17
Age-dependent regenerative mechanisms in the brain	17
Suppression of double-stranded RNA sensing in cancer: molecular mechanisms and therapeutic potential	17
Control of epithelial homeostasis by apical polarity: it takes a network	17
The art of hijacking: how Nsp1 impacts host gene expression during coronaviral infections	17
Folding speeds of helical membrane proteins	17
Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy	17
Genome organization across scales: mechanistic insights from in vitro reconstitution studies	17
Understanding pyrethrin biosynthesis: toward and beyond natural pesticide overproduction	17
Gone with the Wnt(less): a mechanistic perspective on the journey of Wnt	16
Advances in understanding the mechanisms of the human papillomavirus oncoproteins	16
Polycomb-mediated histone modifications and gene regulation	16
How do spherical bacteria regulate cell division?	16
How far can omics go in unveiling the mechanisms of floral senescence?	16
GPX4: old lessons, new features	16
Molecular and structural perspectives on protein trafficking to the primary cilium membrane	16
Insights into the cellular consequences of LRRK2-mediated Rab protein phosphorylation	16
Bacterial microcompartments as a next-generation metabolic engineering tool: utilizing nature's solution for confining challenging catabolic pathways	16
Nano-organization of synaptic calcium signaling	15
Cell-free genomics: transcription factor interactions in reconstituted naïve embryonic chromatin	15
Striving for sustainable biosynthesis: discovery, diversification, and production of antimicrobial drugs in Escherichia coli	15
Mechanisms of epithelial growth and development in the zebrafish intestine	15
Specific isotopic labelling and reverse labelling for protein NMR spectroscopy: using metabolic precursors in sample preparation	15
Timely symbiosis: circadian control of legume-rhizobia symbiosis	15
Eliminating oncogenic RAS: back to the future at the drawing board	15
Advancing our knowledge of antigen processing with computational modelling, structural biology, and immunology	15
Regulation of mTORC1 by the Rag GTPases	15
Should I stay or should I go: TFIIIC as assembly factor and barrier in RNA polymerase III transcription	15
The emerging theme of 3′UTR mRNA isoform regulation in reprogramming of cell metabolism	15
One genome, multiple phenotypes: decoding the evolution and mechanisms of environmentally induced developmental plasticity in insects	15
Studying histone inheritance in different systems using imaging-based methods and perspectives	15
Lessons from natural molecular glue degraders	15
Human E3 ubiquitin ligases: accelerators and brakes for SARS-CoV-2 infection	15
Satellite cell dynamics during skeletal muscle hypertrophy	15
Targeting NRF2 to promote epithelial repair	15
Using genomics to understand the mechanisms of virulence and drug resistance in fungal pathogens	15
Computational approaches to understand transcription regulation in development	15
An update on the role of sex hormones in the function of the cardiorenal mitochondria	15
Intersectin — many facets of a scaffold protein	15
Unravelling mechanisms that govern meiotic crossover formation in wheat	14
Nesprin-1: novel regulator of striated muscle nuclear positioning and mechanotransduction	14
A closer look at the role of deubiquitinating enzymes in the Hypoxia Inducible Factor pathway	14
Advances in utilizing reverse micelles to investigate membrane proteins	14
Current working models of SMC-driven DNA-loop extrusion	14
Recent advances in understanding the role of extracellular vesicles from probiotics in intestinal immunity signaling	14
Enhancer target prediction: state-of-the-art approaches and future prospects	14
The molecular mechanisms driving Plasmodium cell division	14

Effects of antibiotics on bacterial cell morphology and their physiological origins	14
The molecular mechanisms of human separase regulation	14
Viral subversion of the cell polarity regulator Scribble	13
The remodeling of Z-DNA in the mammalian germ line	13
Atomic force microscopy 3D structural reconstruction of individual particles in the study of amyloid protein assemblies	13
DIG-DUBs: mechanisms and functions of ISG15 deconjugation by human and viral cross-reactive ubiquitin proteases	13
Redesigning miR-34a: structural and chemical advances in the therapeutic development of an miRNA anti-cancer agent	13
SUMO and the DNA damage response	13
How do different cell populations orchestrate myelin regeneration?	13
CRISPRi: a way to integrate iPSC-derived neuronal models	13
Effectors and effects of arginine methylation	13
Correction: Exploring the influence of anionic lipids in the host cell membrane on viral fusion	13
Modification of extracellular matrix proteins by oxidants and electrophiles	13
Endothelial Neuropilin-1: a multifaced signal transducer with an emerging role in inflammation and atherosclerosis beyond angiogenesis	13
Strength in numbers: effect of protein crowding on the shape of cell membranes	13
Differential functions of the KRAS splice variants	13
Current understanding of heparanase 2 regulation, a non-heparanase	13
Mapping lipid pathways during phagocytosis	12
NLR immune receptors: structure and function in plant disease resistance	12
Engineering CRISPR guide RNAs for programmable RNA sensors	12
Deubiquitinases in muscle physiology and disorders	12
The role of PQBP1 in neural development and function	12
Quaternary arrangements of membrane proteins: an aquaporin case	12
DNA translocation by the CMG helicase: the helical inchworm model	12
Dopamine synthesis and transport: current and novel therapeutics for parkinsonisms	12
Interactions between zinc and NRF2 in vascular redox signalling	12
The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation	12
Proofreading mechanisms of the innate immune receptor RIG-I: distinguishing self and viral RNA	12
Developing high-affinity, oxygen-insensitive [NiFe]-hydrogenases as biocatalysts for energy conversion	12
Scaffolds and the scaffolding domain: an alternative paradigm for caveolin-1 signaling	12
Beyond expectations: the development and biological activity of cytokinin oxidase/dehydrogenase inhibitors	12
Is bRaQCing bad? New roles for ribosome associated quality control factors in stress granule regulation	11
Beyond the mono-nucleosome	11
Regulation of cardiomyocyte intracellular trafficking and signal transduction by protein palmitoylation	11
Towards a phylogenetically informed approach to solving protein–protein interactions	11
Progress in recapitulating morphogenesis of blood microvascular structures for microphysiological systems development	11
Exploring microRNAs in craniofacial regenerative medicine	11
The molecular mechanisms of the bacterial iron sensor IdeR	11
Activation is only the beginning: mechanisms that tune kinase substrate specificity	11
Emerging liquid biopsy tools to analyse cancer biomarkers: electrochemical sensors and extracellular vesicle analysis	11
Advances in nanobody multimerization and multispecificity: from in vivo assembly to in vitro production	11
Technology to the rescue: how to uncover the role of transposable elements in preimplantation development	11
ESCRTing the RABs through conversion	11
Force writes memory: proline isomerization as a molecular memory switch	11
Phase separation and viral factories: unveiling the physical processes supporting RNA packaging in dsRNA viruses	11
A multi-dimensional view of context-dependent G protein-coupled receptor function	11
Post-translational regulation of the low-density lipoprotein receptor provides new targets for cholesterol regulation	11
Discovery of telomerase inhibitors: existing strategies and emerging innovations	11
ATP binding to Nerve Growth Factor (NGF) and pro-Nerve Growth Factor (proNGF): an endogenous molecular switch modulating neurotrophins activity	11
The NMDAR-BK channelosomes as regulators of synaptic plasticity	11
The cellular dynamics of neural tube formation	11
Mechanistic insights into protein folding by the eukaryotic chaperonin complex CCT	11
SMC-based immunity against extrachromosomal DNA elements	11
Single-molecule study of the dynamics of the molecular chaperone Hsp70 during the functional cycle	11
Kinetochore–microtubule error correction for biorientation: lessons from yeast	11
New insights into the mechanochemical coupling mechanism of kinesin–microtubule complexes from their high-resolution structures	11
The functional importance of bacterial oxidative phosphonate pathways	11
Insights into mechanisms of ubiquitin ADP-ribosylation reversal	11
Allosteric regulation and inhibition of protein kinases	10
ALTercations at telomeres: stress, recombination and extrachromosomal affairs	10
The emerging role of Rab proteins in osteoclast organelle biogenesis and function	10
Cytoophidia and filaments: you must unlearn what you have learned	10
Therapeutic targeting of TRAIL death receptors	10
Processing DNA lesions during mitosis to prevent genomic instability	10
Molecular regulators of chemotaxis in human hematopoietic stem cells	10
The interactions of amyloid β aggregates with phospholipid membranes and the implications for neurodegeneration	10
Regulation of ATR–CHK1 signaling by ubiquitination of CLASPIN	10
The SWI/SNF ATP-dependent chromatin remodeling complex in cell lineage priming and early development	10
Cytokinin and reproductive shoot architecture: bigger and better?	10
The stabilization of Arp2/3 complex generated actin filaments	10
Histone mutations in cancer	10
Therapeutic targeting of eukaryotic initiation factor (eIF) 4E	10
What voltage-sensing phosphatases can reveal about the mechanisms of ion channel regulation by phosphoinositides	10
Protective HLA-B57: T cell and natural killer cell recognition in HIV infection	10
Mitochondrial DNA as inflammatory DAMP: a warning of an aging immune system?	9
Fast-forward on P-type ATPases: recent advances on structure and function	9
Recent developments in the engineering of Rubisco activase for enhanced crop yield	9
Molecular aspects of Interleukin-36 cytokine activation and regulation	9
Emerging drivers of DNA repeat expansions	9
The long and short of EJC-independent nonsense-mediated RNA decay	9
Regulatory dynamics of arginine metabolism in Staphylococcus aureus	9
Computational modelling of aggressive B-cell lymphoma	9
Laminin N-terminus (LaNt) proteins, laminins and basement membrane regulation	9
Inorganic polyphosphate and ion transport across biological membranes	9
Recent advances in the structure and activation mechanisms of metabolite-releasing Pannexin 1 channels	9
Advances in polarised luminescence approaches to understanding interactions between biomolecules	9
Using modified mRNA for cardiomyocyte proliferation and cardiac genetic disease modelling and treatment	9
Mature beyond their years: young children who escape detection of parasitemia despite living in settings of intense malaria transmission	9
Morphogenesis of leaves: from initiation to the production of diverse shapes	9
The mRNA dynamics underpinning translational control mechanisms of Drosophila melanogaster oogenesis	9
Loss of brain energy metabolism control as a driver for memory impairment upon insulin resistance	9
The O-GlcNAc cycling in neurodevelopment and associated diseases	9
The role of HNF4α in adenocarcinoma	9
Peeking into the future: inferring mechanics in dynamical tissues	9
Structural biology of shelterin and telomeric chromatin: the pieces and an unfinished puzzle	9