Toxicology

Papers
(The median citation count of Toxicology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Oleanolic acid-3-glucoside, a synthetic oleanane-type saponin, ameliorates methylmercury-induced dysfunction of synaptic transmission in mice239
Editorial Board231
Roles of N6-methyladenosine in LncRNA changes and oxidative damage in cadmium-induced pancreatic β-cells179
Investigating the cardiotoxicity of N-n-butyl haloperidol iodide: Inhibition mechanisms on hERG channels131
Activation of α7 nicotinic acetylcholine receptor augments nerve growth factor action on PCtrk cells102
Machine learning classification of steatogenic compounds using toxicogenomics profiles89
Comparison of modes of action between fish, cell and mitochondrial toxicity based on toxicity correlation, excess toxicity and QSAR for class-based compounds64
Differential eigengene network analysis reveals benzo[a]pyrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin consensus regulatory network in human liver cell line HepG263
Deep Learning Algorithm Based on Molecular Fingerprint for Prediction of Drug‐Induced Liver Injury62
Nutrient molecule corona: An update for nanomaterial-food component interactions59
Peritubular myoid cells of the testis produce monocyte chemotactic protein 1 upon direct exposure to Mono-(2-Ethylhexyl) phthalate through the IL-1 signaling pathway58
Two thyroperoxidase-inhibiting chemicals induce shared transcriptional changes in hippocampus of developing rats58
Preconception exposure to dibutyl phthalate (DBP) impairs spermatogenesis by activating NF-κB/COX-2/RANKL signaling in Sertoli cells58
The novel polyfluoroalkyl benzenesulfonate OBS exposure induces cell cycle arrest and senescence of rat pituitary cell GH3 via the p53/p21/RB pathway56
Corrigendum to “Effects of perinatal exposure to bisphenol A on induction of prostate cancer in Sprague Dawley rats by MNU and testosterone” [Toxicology 484 (2023) 153394]54
Corrigendum to “Maternal linuron exposure alters testicular development in male offspring rats at the whole genome level” [Toxicology 389 (2017) 13–20]49
Exploring cardiac impact of oral nicotine exposure in a transplantable Neoplasm Mice Model: Insights from biochemical analysis, morphometry, and molecular docking: Chlorella vulgaris green algae suppo46
Editorial Board Members46
MCLR-elicited hepatic fibrosis and carcinogenic gene expression changes persist in rats with diet-induced nonalcoholic steatohepatitis through a 4-week recovery period44
Comprehensive analysis based in silico study of alternative bisphenols – Environmental explanation of prostate cancer progression44
Prediction of drug-induced mitochondrial dysfunction using succinate-cytochrome c reductase activity, QSAR and molecular docking44
Exposure to a combination of MWCNTs and DBP causes splenic toxicity in mice42
Ferrostatin‑1 alleviates liver injury via decreasing ferroptosis following ricin toxin poisoning in rat41
Comparative study on gene expression profiles in the liver of male neonatal mice prenatally exposed to PFOA and its alternative HFPO-DA41
Synergism in actions of HBV with aflatoxin in cancer development40
Uric acid accumulation in the kidney triggers mast cell degranulation and aggravates renal oxidative stress40
The formation of lamellar body-like structures may be a trigger of cetylpyridinium chloride-induced cell death and inflammatory response40
MLKL triggers NLRP3 activation in sodium arsenite-induced myocardial necroinflammation39
Dimethyl fumarate induces cardiac developmental toxicity in zebrafish via down-regulation of oxidative stress39
IL-10-TG/TPO-T4 axis, the target of bis (2-ethylhexyl) tetrabromophthalate on thyroid function imbalance39
A preliminary study of combined toxicity and underlying mechanisms of imidacloprid and cadmium coexposure using a multiomics integration approach38
Per- and polyfluoroalkyl substances as potentiators of hepatotoxicity in an exposome framework: Current challenges of environmental toxicology38
Edible vegetables grown in the vicinity of electronic wastes: A study of potential health risks and DNA damage in consumers37
The effects of hexabromocyclododecane on the transcriptome and hepatic enzyme activity in three human HepaRG-based models36
Necroptosis contributes to airborne particulate matter-induced ocular surface injury36
Influence of aryl hydrocarbon receptor and sulfotransferase 1A1 on bisphenol AF-induced clastogenesis in human hepatoma cells35
The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice34
A mechanistic toxicology study to grasp the mechanics of zearalenone estrogenicity: Spotlighting aromatase and the effects of its genetic variability34
Corrigendum to “Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats” [Toxicology 449 (2021) 152665]34
Copper oxide nanoparticles disrupt lysosomal function and promote foam cell formation in RAW264.7 macrophages33
Di-(2-ethylhexyl) phthalate induces prepubertal testicular injury through MAM-related mitochondrial calcium overload in Leydig and Sertoli cell apoptosis33
Triclosan has a strong influence on the development of mouse preimplantation embryo via activating miR-134/Nanog axis32
The Cost Outcome Pathway framework: Integrating socio-economic impacts to Adverse Outcome Pathways for supporting policy makers31
Integrated in silico analysis for the identification of key genes and signaling pathways in copper oxide nanoparticles toxicity31
Novel flame retardants (NFRs) in e-waste: Environmental burdens, health implications, and recommendations for safety assessment and sustainable management30
High-throughput screening of respiratory hazards: Exploring lung surfactant inhibition with 20 benchmark chemicals30
Lambda cyhalothrin and chlorantraniliprole caused biochemical, histological, and immunohistochemical alterations in male rabbit liver: Ameliorative effect of vitamins A, D, E, C mixture29
Organochlorine pesticides: occurrence, spatial distribution of residues, toxicity, and toxic mechanisms29
Acrolein inhalation acutely affects the regulation of mitochondrial metabolism in rat lung29
Microplastics/nanoplastics and neurological health: An overview of neurological defects and mechanisms29
Establishment of a point of departure for CBD hepatotoxicity employing human HepaRG spheroids29
Neurotoxicity of Tris (1,3-dichloroisopropyl) phosphate in Caenorhabditis elegans29
Gold nanoparticle intratesticular injections as a potential animal sterilization tool: Long-term reproductive and toxicological implications28
Legacy and alternative per- and polyfluoroalkyl substances (PFAS) alter the lipid profile of HepaRG cells28
Chemical effects on neural network activity: Comparison of acute versus network formation exposure in microelectrode array assays27
Editorial Board Members27
Predicting in vitro assays related to liver function using probabilistic machine learning27
OTSSP167 leads to follicular dysplasia and negatively affects oocyte quality in mice27
Predictive, integrative, and regulatory aspects of AI-driven computational toxicology – Highlights of the German Pharm-Tox Summit (GPTS) 202427
Editorial Board Members26
Assessment of transplacental and lactational genotoxicity of tembotrione in Wistar rats at different developmental stages by alkaline comet assay26
Effects of intrauterine exposure to concentrated ambient particles on allergic sensitization in juvenile mice25
Chronic consumption of food-additives lead to changes via microbiota gut-brain axis25
Comparison of two different toxin-induced kidney fibrosis models in terms of inflammatory responses24
Effects of ELF-PEMF exposure on spontaneous alternation, anxiety, motor co-ordination and locomotor activity of adult wistar rats and viability of C6 (Glial) cells in culture24
MLKL deficiency alleviates acute alcoholic liver injury via inhibition of NLRP3 inflammasome24
Protection from benzene-induced immune dysfunction in mice24
Increased TSLP and oxidative stress reflect airway epithelium injury upon cigarette smoke exposure. Is there a role for carbocysteine?24
Pb inhibited C2C12 myoblast differentiation by regulating HDAC223
Corrigendum to “Inhibitory effects of parabens on human and rat 17β-hydroxysteroid dehydrogenase 1: Mechanisms of action and impact on hormone synthesis” Toxicology 506 (August) (2024) 15387323
Cytotoxicity and pro-inflammatory effect of polystyrene nano-plastic and micro-plastic on RAW264.7 cells23
Fine particulate matter disrupts bile acid homeostasis in hepatocytes via binding to and activating farnesoid X receptor23
ROS-mediated NRF2/p-ERK1/2 signaling-involved mitophagy contributes to macrophages activation induced by CdTe quantum dots23
GenX induces fibroinflammatory gene expression in primary human hepatocytes23
Toxic talk: pannexin1 channel communication as an emerging mechanism of toxicity23
Assessing micro and nanoplastics toxicity using rodent models: Investigating potential mitochondrial implications23
Exposure to polystyrene nanoplastics promotes premature cellular senescence through mitochondrial ROS production and dysfunction in pre-differentiated skeletal myoblasts23
Benzyl butyl phthalate promotes ferroptosis in Sertoli cells via disrupting ceruloplasmin-mediated iron balance22
Ferroptosis is involved in cisplatin sensitivity of the S3 segment of immortalized proximal tubule cells22
Immunosuppression characterized by increased Treg cell and IL-10 levels in benzene-induced hematopoietic toxicity mouse model22
Corrigendum to “Chronic oral depleted uranium leads to reproductive damage in male rats through the ROS-hnRNP A2/B1-COX-2 signaling pathway” [Toxicology 449 (2021) 152666]22
Immunotoxicity of 2-Acetyl-4-tetrahydroxybutylimidazole in BALB/c mice with different vitamin B6 nutritional statuses21
Hematological, cardiovascular and oxidative DNA damage markers associated with heavy metal exposure in electronic waste (e-waste) workers of Bangladesh21
Role of miR-145-5p/ CD40 in the inflammation and apoptosis of HUVECs induced by PM2.521
Protective effect of dental pulp stem cells' conditioned medium against cisplatin-induced testicular damage in rats21
NAM-based prediction of point-of-contact toxicity in the lung: A case example with 1,3-dichloropropene21
The p,p’-DDE disturbs the M1 function without affecting the M2 phenotype nor unstimulated bone marrow-derived macrophages from BALB/c mice21
N-isopropylbenzylamine, a methamphetamine mimics, produces toxicity via increasing nitric oxide in vitro21
A comprehensive review of the proline mimic azetidine-2-carboxylic acid (A2C)20
Corrigendum to “Graphene quantum dots (GQDs) induce thigmotactic effect in zebrafish larvae via modulating key genes and metabolites related to synaptic plasticity” [Toxicology 487 (2023) 1–13]20
PM2.5 induces mitochondrial dysfunction via AHR-mediated cyp1a1 overexpression during zebrafish heart development20
Nicotine stimulates IL-8 expression via ROS/NF-κB and ROS/MAPK/AP-1 axis in human gastric cancer cells20
Editorial Board20
Environmental factors modulating protein conformations and their role in protein aggregation diseases20
Identifying the link between chemical exposures and breast cancer in African American women via integrated in vitro and exposure biomarker data20
The mechanism of the neuroprotective effect of zinc against cadmium-induced behavioral impairments in male Wister rats: Focus on tryptophan degradation pathway, oxidative-inflammatory stress, and hist20
The effects of fumonisin B1 on intercellular communications and miRNA modulations: Non-genotoxic carcinogenesis mechanisms in human kidney cells20
In vitro toxicological evaluation of glo menthol and non-menthol heated tobacco products20
Editorial Board20
Editorial Board Members20
Genomic comparisons between hepatocarcinogenic and non-hepatocarcinogenic organophosphate insecticides in the mouse liver20
Endocrine toxicity of atrazine and its underlying mechanisms20
PCB126 induced toxic actions on liver energy metabolism is mediated by AhR in rats20
Multi-omics analysis reveals BPF exposure causes hepatic glucose and lipid metabolism disorder in rats by disrupting energy homeostasis20
Exposure to volatile organic compounds induces cardiovascular toxicity that may involve DNA methylation19
Extracellular histones cause intestinal epithelium injury and disrupt its barrier function in vitro and in vivo19
Mechanisms and treatment strategies of organophosphate pesticide induced neurotoxicity in humans: A critical appraisal19
Gestational exposure to BPA alters the expression of glucose and lipid metabolic mediators in the placenta: Role in programming offspring for obesity19
Immunotoxic effect and mechanisms of Fusarium mycotoxins on human immune cells: A focus on T cells and macrophages19
Influence of polystyrene nanoparticles on the toxicity of tetrabromobisphenol A in human intestinal cell lines18
Neonatal exposure of bisphenol A led to increased lipolysis of visceral adipose tissue in adult rats with DNA hypomethylation of Atgl being one of the possible underlying mechanisms18
Bisphenol A induced neuronal apoptosis and enhanced autophagy in vitro through Nrf2/HO-1 and Akt/mTOR pathways18
Interaction and toxicity of ingested nanoparticles on the intestinal barrier18
Exposure to TCBPA stimulates the growth of arterial smooth muscle cells through the activation of the ROS/NF-κB/NLRP3 signaling pathway18
Maternal urban particulate matter exposure and signaling pathways in fetal brains and neurobehavioral development in offspring18
A Benchmark analysis of acrylamide-derived DNA adducts in rat hepatocytes in culture measured by a new, highly sensitive method18
Retraction notice to “Arsenic-induced mitochondrial instability leading to programmed cell death in the exposed individuals" [Toxicology 246 (2008) 101–111]18
Three-dimensional cultured ampullae from rats as a screening tool for vestibulotoxicity: Proof of concept using styrene18
Kupffer cells play a crucial role in monocrotaline-induced liver injury by producing TNF-α18
Effects of methoxychlor on broiler gut microbiota and liver and its residue accumulation risk to human health18
Mitochondria damage and ferroptosis involved in Ni-induced hepatotoxicity in mice18
Advice on assistance and protection provided by the Scientific Advisory Board of the Organisation for the Prohibition of Chemical Weapons: Part 3. On medical care and treatment of injuries from sulfur17
A microRNA signature for valproate-induced steatosis in human hepatocytes and its application to predict fatty liver in paediatric epileptic patients on valproate therapy17
Considerations for future quantitative structure-activity relationship (QSAR) modelling for heavy metals – A case study of mercury17
Editorial Board Members17
The effects and mechanism of LncRNA NORAD on doxorubicin-induced cardiotoxicity17
Polystyrene microplastics induced oxidative stress, inflammation and necroptosis via NF-κB and RIP1/RIP3/MLKL pathway in chicken kidney17
Editorial Board17
Comprehensive analysis of the impact of emerging flame retardants on prostate cancer progression: The potential molecular mechanisms and immune infiltration landscape17
A computational study on the biotransformation of alkenylbenzenes by a selection of CYPs: Reflections on their possible bioactivation17
Bmi1 signaling maintains the plasticity of airway epithelial progenitors in response to persistent silica exposures17
Exposure to organophosphate flame retardants and phthalates alters neuronal activity and network development17
Recombinant Klotho alleviates vancomycin-induced acute kidney injury by upregulating anti-oxidative capacity via JAK2/STAT3/GPx3 axis17
Dynamic analysis of intrahepatic T cells reveals a unique group of restorative Cxcr3 tissue-resident CD4 T cells in acute liver injury17
CYP2E1 mediated deoxynivalenol-induced hepatocyte toxicity by regulating ferroptosis17
The PD1 inhibitory pathway and mature dendritic cells contribute to abacavir hypersensitivity in human leukocyte antigen transgenic PD1 knockout mice17
Effect of the extra-nuclear cation on the cytotoxicity and mechanism of action of pyridine-2,6-dicarboxylate Ga(III) complexes17
Knock-down of FOXO3, GATA2, NFE2L2 and AHR promotes doxorubicin-induced cardiotoxicity in human cardiomyocytes17
Comparative evaluation of mutagenic, genotoxic, cytotoxic, and antimicrobial effects of flavour and fragrance aldehydes, ketones, oximes, and oxime ethers17
Chronic D-galactose administration induces natural aging characteristics, in rat’s brain and heart16
The variability in CYP3A4 activity determines the metabolic kinetic characteristics of ketamine16
Embryonic exposure to GenX causes reproductive toxicity by disrupting the formation of the blood-testis barrier in mouse offspring16
Silica nanoparticles induce pulmonary damage in rats via VEGFC/D–VEGFR3 signaling-mediated lymphangiogenesis and remodeling16
Tetrabromobisphenol S (TBBPS) exposure causes gastric cell senescence and inflammation by inducing iron overload16
Lycium barbarum polysaccharides attenuate nonylphenol and octylphenol-induced oxidative stress and neurotransmitter disorders in PC-12 cells16
Dihydrotestosterone induces reactive oxygen species accumulation and mitochondrial fission leading to apoptosis of granulosa cells16
Polystyrene microplastics aggravate acute pancreatitis in mice16
Autophagy alleviates hippocampal neuroinflammation by inhibiting the NLRP3 inflammasome in a juvenile rat model exposed particulate matter16
Long-term exposure to polystyrene microplastics reduces macrophages and affects the microbiota–gut–brain axis in mice15
Hepatic lipid metabolism disorders and immunotoxicity induced by cysteamine in early developmental stages of zebrafish15
Developments in the field of intestinal toxicity and signaling pathways associated with rodent exposure to micro(nano)plastics15
Bioaccessibility as a determining factor in the bioavailability and toxicokinetics of cadmium compounds15
Teratological, neurochemical and histomorphic changes in the limbic areas of F1 mice progeny due to co-parental polystyrene nanoplastic exposure15
Health impacts of PM2.5 emissions from brake pad wear: A comprehensive study on pulmonary, metabolic, and microbiota alterations15
Acute cytotoxicity of mineral fibres observed by time-lapse video microscopy15
RNA-Seq approach to investigate the effects of melatonin on bone marrow-derived dendritic cells from dextran sodium sulfate-induced colitis mice15
Ameliorative effects of the phytochemicals in dates (Phoenix dactylifera) against the toxicological changes induced by fipronil in male albino rats15
Evaluation of mutagenic, cytotoxic, mitochondrial dysfunction, apoptotic activity, and acute toxicity of ethanolic extract of Cissus quadrangularis15
Sintilimab combined with acetaminophen aggravates liver injury through apoptotic and disturbed bile acid pathways15
The impact of legacy and novel perfluoroalkyl substances on human cytochrome P450: An in vitro study on the inhibitory potential and underlying mechanisms15
Fluoride induced metabolic disorder of endothelial cells15
Hematological consequences of polyethylene microplastics toxicity in male rats: Oxidative stress, genetic, and epigenetic links15
Ochratoxin A stimulates release of IL-1β, IL–18 and CXCL8 from cultured human microglia15
The effects of direct addition of lead(ii) acetate to a human in vitro model of hematopoiesis recapitulates exposure to lead in utero15
Differential susceptibility of Leydig and Sertoli cells to bisphenol A15
Arsenic induces metabolome remodeling in mature human adipocytes14
Editorial Board Members14
Graphene quantum dots disturbed the energy homeostasis by influencing lipid metabolism of macrophages14
Association of endocrine disrupting chemicals levels in serum, environmental risk factors, and hepatic function among 5- to 14-year-old children14
Genotoxicity assessment of 1,4-anhydro-4-seleno-D-talitol (SeTal) in human liver HepG2 and HepaRG cells14
Role of myo-inositol in acute kidney injury induced by cisplatin14
Effect of persistent organic pollutants in patients with ischemic stroke and all stroke: A systematic review and meta-analysis14
Upregulation of postsynaptic cAMP/PKA/CREB signaling alleviates copper(Ⅱ)-induced oxidative stress and pyroptosis in MN9D cells14
O-alkyl and o-benzyl hesperetin derivative-1L attenuates inflammation and protects against alcoholic liver injury via inhibition of BRD2-NF-κB signaling pathway14
Neurotoxic effects and cognitive decline induced by Aniline Blue dye in an in-vivo zebrafish model14
Sodium arsenite accelerates D-galactose-induced aging in the testis of the rat: Evidence for mitochondrial oxidative damage, NF-kB, JNK, and apoptosis pathways14
Effects of perfluorooctanoic acid (PFOA) on gene expression profiles via nuclear receptors in HepaRG cells: Comparative study with in vitro transactivation assays14
6PPD induces apoptosis and autophagy in SH-SY5Y cells via ROS-mediated PI3K/AKT/mTOR pathway: In vitro and in silico approaches14
Evaluation of toxicological effects of bisphenol S with an in vitro human bone marrow mesenchymal stem cell: Implications for bone health14
Investigation of a broad diversity of nanoparticles, including their processes, as well as toxicity testing in diverse organs and systems14
Ophiopogonin D′-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells14
Lycopene alleviates Deoxynivalenol-induced toxicity in Porcine intestinal epithelial cells by mediating mitochondrial function13
Environmentally relevant concentrations of individual per- and polyfluoroalkyl substances (PFAS) and a PFAS mixture impact proliferation, migration, and gene transcription in a human myometrial cell l13
Di-n-butyl phthalate regulates vascular smooth muscle cells phenotypic switching by MiR-139–5p-MYOCD pathways13
Toxicological Evaluation of Vape Liquids Circulating in Brazil: Evidence of Emerging Hazards13
Editorial Board Members13
Utilization of the CometChip assay for detecting PAH-induced DNA bulky adducts in a 3D primary human bronchial epithelial cell model13
Virtual display of targets: A new level to rise the current understanding of ochratoxin A toxicity from a molecular standpoint13
Obituary for Karl Joachim Netter13
Mechanisms involved in pro-inflammatory responses to traffic-derived particulate matter (PM) in THP-1 macrophages compared to HBEC3-KT bronchial epithelial cells13
AFB1 consolidates HBV harm to induce liver injury and carcinogenic risk by inactivating FTCD-AS1-PXR-MASP1 axis13
Cadmium promotes hyaluronan synthesis by inducing hyaluronan synthase 3 expression in cultured vascular endothelial cells via the c-Jun N-terminal kinase–c-Jun pathway13
Ripretinib induced skeletal muscle toxicity through mitochondrial impairment in C2C12 myotubes13
Long-term exposure to arsenic in drinking water leads to myocardial damage by oxidative stress and reduction in NO13
In vitro test battery for testing molecular initiating events in chemical-induced cholestasis13
Editorial Board Members13
Effect of modified citrus pectin on galectin-3 inhibition in cisplatin-induced cardiac and renal toxicity13
The crucial involvement of gamma-Mangostin and CYP1B1 in the mechanism underlying the toxicity caused by cigarette smoke extract: In silico and in vitro insights13
Sorafenib is an antagonist of the aryl hydrocarbon receptor13
Dynamics and mechanisms of bioaccumulation and elimination of nonylphenol in zebrafish13
A metabolomic approach to study triptolide-induced ovarian damage in rats13
Loperamide induces excessive accumulation of bile acids in the liver of mice with different diets13
Molecular mechanisms of developmental toxicity induced by BBP in zebrafish embryos13
Increasing confidence in new approach methodologies for inhalation risk assessment with multiple end point assays using 5-day repeated exposure to 1,3-dichloropropene13
Tobacco smoking exposure-mediated ELAVL1 regulates bladder cancer cell senescence via autophagy activation12
Repeat-dose and local tolerance toxicity of SARS-CoV-2 FINLAY-FR-02 vaccine candidate in Sprague Dawley rats12
BPA exposure aggravates necroptosis of myocardial tissue in selenium deficient broilers through NO-dependent endoplasmic reticulum stress12
Per- and poly-fluoroalkyl substances (PFAS) and female reproductive outcomes: PFAS elimination, endocrine-mediated effects, and disease12
Investigating the functional role of BUB1B in aflatoxin B1-associated hepatocarcinogenesis12
Lung metabolome of 1,3-butadiene exposed Collaborative Cross mice reflects metabolic phenotype of human lung cancer12
MCF-7 cell - derived exosomes were involved in protecting source cells from the damage caused by tributyltin chloride via transport function12
Prenatal exposure to dibutyl phthalate contributes to erectile dysfunction in offspring male rats by activating the RhoA/ROCK signalling pathway12
Association between occupational lead exposure and immunotoxicity markers: A systematic review and meta-analysis12
Polystyrene microplastics trigger colonic inflammation in rats via the TLR4/NF-κB/COX-2 pathway and modulation of intestinal microbiota12
Toxicity evaluation of particles formed during 3D-printing: Cytotoxic, genotoxic, and inflammatory response in lung and macrophage models12
Chlorpyrifos impairs sperm parameters and number of Sertoli and Leydig cells in rats after exposure during the peripubertal period12
Editorial Board Members12
Graphene quantum dots (GQDs) induce thigmotactic effect in zebrafish larvae via modulating key genes and metabolites related to synaptic plasticity12
Cadmium induces spontaneous abortion by impairing endometrial stromal cell decidualization12
InterDIA: Interpretable prediction of drug-induced autoimmunity through ensemble machine learning approaches12
Geniposide suppresses thermogenesis via regulating PKA catalytic subunit in adipocytes12
Exploring the dynamics of the ABCB1 membrane transporter P-glycoprotein in the presence of ATP and active/non-active compounds through molecular dynamics simulations11
Effects of endocrine disrupting chemicals on the expression of RACK1 and LPS-induced THP-1 cell activation11
Mirabegron alleviates acetic acid-induced colitis in rats: Role of adiponectin and GSTM1/GSH detoxification pathway11
Immunotoxicity of relevant mixtures of pesticides and metabolites on THP-1 cells11
Glutathione attenuates diesel exhaust-induced lung epithelial injury via NF-κB/Nrf2/GPX4-mediated ferroptosis11
Occurrence and ecotoxicological impacts of polybrominated diphenyl ethers (PBDEs) in electronic waste (e-waste) in Africa: Options for sustainable and eco-friendly management strategies11
Effect of monosultap on notochord development in zebrafish (Danio rerio) embryos11
Editorial Board11
Oxidative metabolism in the cardiorespiratory system after an acute exposure to nickel-doped nanoparticles in mice11
‘Corrigendum to: “Bayesian benchmark dose analysis for inorganic arsenic in drinking water associated with bladder and lung cancer using epidemiological data” [Toxicology 455 (2021) 152752]’11
Prediction of polybrominated diphenyl ethers (PBDEs) as potential substrates of various human CYP enzymes and laboratory test of BDE-99 for its metabolism-activated mutagenicity11
Close association between the synergistic toxicity of zearalenone-deoxynivalenol combination and microRNA221-mediated PTEN/PI3K/AKT signaling in HepG2 cells11
Cellular targets of mefloquine11
Neurodevelopment effects of early life bisphenol-A exposure on visual memory: Insights into recovery dynamics11
Identification of circRNA expression profiles and the potential role of hsa_circ_0006916 in silicosis and pulmonary fibrosis11
Regulating of LncRNA2264/miR-20b-5p/IL17RD axis on hydrogen sulfide exposure-induced inflammation in broiler thymus by activating MYD88/NF-κB pathway11
Chronic low-level exposure to Pb, Hg, and Cd mixture triggers brain premature aging in rat11
ToxProfiler: A novel human-based reporter assay for in vitro chemical safety assessment11
Alternative animal models in predictive toxicology11
Resveratrol protected acrolein-induced ferroptosis and insulin secretion dysfunction via ER-stress- related PERK pathway in MIN6 cells10
Bag2 protects against doxorubicin-induced cardiotoxicity by maintaining Pink1-mediated mitophagy10
Innovation in drug toxicology: Application of mass spectrometry imaging technology10
Clinical and experimental research progress on neurotoxicity of sulfur mustard and its possible mechanisms10
Assessing the impact of TiO2 nanomaterials on intestinal cells: New evidence for epithelial translocation and potential pro-inflammatory effects10
Per- and polyfluoroalkyl substances (PFAS) augment adipogenesis and shift the proteome in murine 3T3-L1 adipocytes10
Effects of radon exposure on gut microbiota and its metabolites short-chain fatty acids in mice10
Preclinical liver toxicity models: Advantages, limitations and recommendations10
Antimony induces mitochondria-dependent and ER stress-triggered apoptosis via the oxidative stress-activated JNK signaling pathway in pancreatic islet β-cells10
Effects of miR-200b-3p and miR-424–5p regulating notch signaling pathway on atherosclerosis induced by PM2.5 in vitro10
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