Toxicology

Papers
(The median citation count of Toxicology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
The effects of Aroclor 1254 alone and in combination with X-rays on the male mice germ cells quantity and quality223
Editorial Board Members153
Are the BPA analogues an alternative to classical BPA? Comparison between 2D and alternative 3D in vitro neuron model to assess cytotoxic and genotoxic effects137
Differential eigengene network analysis reveals benzo[a]pyrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin consensus regulatory network in human liver cell line HepG2112
Editorial Board Members104
Editorial Board Members72
Decrease of an intracellular organic osmolyte contributes to the cytotoxicity of organophosphate in neuroblastoma cells in vitro72
Editorial Board Members66
Safety evaluation of dufulin racemate and its R(S)-enantiomers in rats based on dose-effect relationship, time-effect relationship, and lipidomics63
The potential risks of chronic fluoride exposure on nephrotoxic via altering glucolipid metabolism and activating autophagy and apoptosis in ducks63
Health impacts of PM2.5 emissions from brake pad wear: A comprehensive study on pulmonary, metabolic, and microbiota alterations60
Ferroptosis is involved in trophoblast cells cytotoxicity induced by black phosphorus nanoparticles59
Two thyroperoxidase-inhibiting chemicals induce shared transcriptional changes in hippocampus of developing rats53
Toxic effect and mRNA mechanism of moon dust simulant induced pulmonary inflammation in rats49
Ozone exposure promotes pyroptosis in rat lungs via the TLR2/4-NF-κB-NLRP3 signaling pathway45
The formation of lamellar body-like structures may be a trigger of cetylpyridinium chloride-induced cell death and inflammatory response43
Nutrient molecule corona: An update for nanomaterial-food component interactions43
Benzo(a)pyrene promotes the malignant progression of malignant-transformed BEAS-2B cells by regulating YTH N6-methyladenosine RNA binding protein 1 to inhibit ferroptosis42
An integrated approach, based on mass spectrometry, for the assessment of imidacloprid metabolism and penetration into mouse brain and fetus after oral treatment42
Benzopyrene represses mitochondrial fission factors and PINK1/Parkin-mediated mitophagy in primary astrocytes40
Effects of perfluorooctanoic acid (PFOA) on gene expression profiles via nuclear receptors in HepaRG cells: Comparative study with in vitro transactivation assays38
Phosphocreatine attenuates doxorubicin-induced cardiotoxicity by inhibiting oxidative stress and activating TAK1 to promote myocardial survival in vivo and in vitro37
The efficacy and toxicity of antineoplastic antimetabolites: Role of gut microbiota37
Germ-free status but not subacute polychlorinated biphenyl (PCB) exposure altered hepatic phosphatidylcholine and ether-phosphatidylcholine levels in mice36
Human risk assessment of inhaled irritants: Role of sensory stimulations from spatially separated nociceptors36
In vitro toxicity and chemical analysis of e-cigarette aerosol produced amid dry hitting36
Cyanotoxin exposure and hepatocellular carcinoma36
A review on toxicity mechanism and risk factors of nanoparticles in respiratory tract35
Combining transcriptomics and metabolomics to assess neurodevelopmental alteration caused by in utero exposure of mice to three putative thyroid hormone system disruptors35
Urinary GM2AP coincides with renal cortical damage and grades cisplatin nephrotoxicity severity in rats34
Caffeine disrupts ataxia telangiectasia mutated gene-related pathways and exacerbates acetaminophen toxicity in human fetal immortalized hepatocytes33
An in-depth examination of Per- and Polyfluoroalkyl (PFAS) effects on transporters, with emphasis on the ABC superfamily: A critical review33
Editorial Board33
The novel polyfluoroalkyl benzenesulfonate OBS exposure induces cell cycle arrest and senescence of rat pituitary cell GH3 via the p53/p21/RB pathway32
Synergism in actions of HBV with aflatoxin in cancer development32
Selenium nanoparticles alleviate deoxynivalenol-induced intestinal epithelial barrier dysfunction by regulating endoplasmic reticulum stress in IPEC-J2 cells32
Uric acid accumulation in the kidney triggers mast cell degranulation and aggravates renal oxidative stress31
Computational and experimental studies on the inhibitory mechanism of hydroxychloroquine on hERG31
Investigation of cannabidiol-induced cytotoxicity in human hepatic cells31
Cigarette smoking exposure breaks the homeostasis of cholesterol and bile acid metabolism and induces gut microbiota dysbiosis in mice with different diets30
Oleanolic acid-3-glucoside, a synthetic oleanane-type saponin, ameliorates methylmercury-induced dysfunction of synaptic transmission in mice30
Pesticide mediated silent neurotoxicity and its unmasking: An update on recent progress30
Safer chemicals using less animals: kick-off of the European ONTOX project30
How does organophosphorus chemical warfare agent exposure affect respiratory physiology in mice?30
Deoxynivalenol induces cell senescence in RAW264.7 macrophages via HIF-1α-mediated activation of the p53/p21 pathway29
Exploring microbiota-gut-brain axis biomarkers linked to autism spectrum disorder in prenatally chlorpyrifos-exposed Fmr1 knock-out and wild-type male rats29
Long-term toxicity evaluation of aristolochic acid-IIIa in mice29
HMGA2-mediated glutamine metabolism is required for Cd-induced cell growth and cell migration28
Analysis of environmental pollutant Bisphenol F elicited prostate injury targets and underlying mechanisms through network toxicology, molecular docking, and multi-level bioinformatics data integratio28
Embryonic ethanol exposure induces oxidative stress and inflammation in zebrafish model: A dose-dependent study28
Genotoxicity assessment of 1,4-anhydro-4-seleno-D-talitol (SeTal) in human liver HepG2 and HepaRG cells27
The zebrafish embryo as a model for chemically-induced steatosis: A case study with three pesticides27
Correlation between inhibition of lung surfactant function in vitro and rapid reduction in tidal volume following exposure to plant protection products in mice.27
Bisphenol S promotes the progression of prostate cancer by regulating the expression of COL1A1 and COL1A227
Pterostilbene attenuates RIPK3-dependent hepatocyte necroptosis in alcoholic liver disease via SIRT2-mediated NFATc4 deacetylation27
Soluble epoxide hydrolase inhibitor can protect the femoral head against tobacco smoke exposure-induced osteonecrosis in spontaneously hypertensive rats26
Editorial Board Members26
Are lithium and its salts genotoxic? Re: Hadrup et al. Pulmonary toxicity, genotoxicity, and carcinogenicity evaluation of molybdenum, lithium, and tungsten: A review. Toxicology 467 (2022) 15309826
CYP3A1 metabolism-based neurotoxicity of strychnine in rat26
In vitro toxicity of fine and coarse particulate matter on the skin, ocular and lung microphysiological cell-culture systems25
Toxicity mechanism of peri-implantation pesticide beta-cypermethrin exposure on endometrial remodeling in early pregnant mice25
Editorial Board Members25
Editorial Board Members25
Editorial Board Members25
Characterization and applicability of a novel physiologically relevant 3D-tetraculture bronchial model for in vitro assessment of respiratory sensitization24
Editorial Board Members24
Editorial Board Members24
Role of myo-inositol in acute kidney injury induced by cisplatin23
Arsenic induces metabolome remodeling in mature human adipocytes22
Comparison of modes of action between fish, cell and mitochondrial toxicity based on toxicity correlation, excess toxicity and QSAR for class-based compounds22
Editorial Board22
A novel three-dimensional Nrf2 reporter epidermis model for skin sensitization assessment22
Cadmium disrupts mitochondrial distribution and activates excessive mitochondrial fission by elevating cytosolic calcium independent of MCU-mediated mitochondrial calcium uptake in its neurotoxicity21
Methylglyoxal-derived hydroimidazolone-1/RAGE axis induces renal oxidative stress and renal fibrosis in vitro and in vivo21
Dimethyl fumarate induces cardiac developmental toxicity in zebrafish via down-regulation of oxidative stress21
Bisphenol S (BPS) induces glioblastoma progression via regulation of EZH2-mediated PI3K/AKT/mTOR pathway in U87-MG cells21
Interaction between retinoic acid and FGF/ERK signals are involved in Dexamethasone-induced abnormal myogenesis during embryonic development21
Vitamin B ameliorates PM2.5-induced kidney damage by reducing endoplasmic reticulum stress and oxidative stress in pregnant mice and HK-221
Cytotoxicity and mechanism of action of metal complexes: An overview20
Ophiopogonin D′-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells20
3-Indolepropionic acid upturned male reproductive function by reducing oxido-inflammatory responses and apoptosis along the hypothalamic-pituitary-gonadal axis of adult rats exposed to chlorpyrifos20
Pulmonary inflammatory responses and retention dynamics of cellulose nanofibrils20
Effect of persistent organic pollutants in patients with ischemic stroke and all stroke: A systematic review and meta-analysis20
Comprehensive analysis based in silico study of alternative bisphenols – Environmental explanation of prostate cancer progression20
Phenanthrene induces autism-like behavior by promoting oxidative stress and mTOR pathway activation19
Prediction of hepatic drug clearance with a human microfluidic four-cell liver acinus microphysiology system19
Cadmium induced mouse spermatogonia apoptosis via mitochondrial calcium overload mediated by IP3R-MCU signal pathway19
Redox-sensitive Nrf2 and MAPK signaling pathways contribute to trichloroethene-mediated autoimmune disease progression19
The role of DRP1- PINK1-Parkin-mediated mitophagy in early cadmium-induced liver damage19
Pinellia ternata lectin induces inflammation through TLR4 receptor and mediates PI3K/Akt/mTOR axis to regulate NF-κB signaling pathway19
New insights into inhibitory nature of triclosan on acetylcholinesterase activity19
Xanthohumol inhibits non-small cell lung cancer by activating PUMA-mediated apoptosis19
Pathways involved in the human vascular Tetrabromobisphenol A response: Calcium and potassium channels and nitric oxide donors19
Enhanced GRP78 protein expression via the IRE1α/ASK1/p38 MAPK pathway during As2O3-induced endoplasmic reticulum stress in BEAS-2B cells19
Assessing the neurotoxicity of the carbamate methomyl in Caenorhabditis elegans with a multi-level approach18
In silico assessment of mixture toxicity mechanisms involved in the pathogenesis of thyroid diseases: The combination of toxic metal(oid)s and decabrominated diphenyl ether18
Graphene quantum dots disturbed the energy homeostasis by influencing lipid metabolism of macrophages18
Iron overload inhibits cell proliferation and promotes autophagy via PARP1/SIRT1 signaling in endometriosis and adenomyosis18
Newly scheduled carbamate compounds: A synopsis of their properties and development, and considerations for the scientific community18
Non-cytotoxic dosage of fumonisin B1 aggravates ochratoxin A-induced nephrocytotoxicity and apoptosis via ROS-dependent JNK/MAPK signaling pathway18
MCLR-elicited hepatic fibrosis and carcinogenic gene expression changes persist in rats with diet-induced nonalcoholic steatohepatitis through a 4-week recovery period17
Association of endocrine disrupting chemicals levels in serum, environmental risk factors, and hepatic function among 5- to 14-year-old children17
Deep Learning Algorithm Based on Molecular Fingerprint for Prediction of Drug‐Induced Liver Injury17
Bisphenol A exposure prenatally delays bone development and bone mass accumulation in female rat offspring via the ERβ/HDAC5/TGFβ signaling pathway17
Maternal exposure to PM2.5 decreases ovarian reserve in neonatal offspring mice through activating PI3K/AKT/FoxO3a pathway and ROS-dependent NF-κB pathway17
Salidroside alleviates liver inflammation in furan-induced mice by regulating oxidative stress and endoplasmic reticulum stress17
Acute cytotoxicity of mineral fibres observed by time-lapse video microscopy17
Intermittent exposure to chlorpyrifos results in cardiac hypertrophy and oxidative stress in rats17
Effects of lanthanum nitrate on behavioral disorder, neuronal damage and gene expression in different developmental stages of Caenorhabditis elegans17
Inhibition by pesticides of the DJ-1/Park7 protein related to Parkinson disease.17
Molecular docking study of frequently used food additives for selected targets depending on the chromosomal abnormalities they cause17
Teratological, neurochemical and histomorphic changes in the limbic areas of F1 mice progeny due to co-parental polystyrene nanoplastic exposure16
An integrated in silico-in vitro investigation to assess the skin sensitization potential of 4-Octylphenol16
Neurotoxicity of ochratoxin A: Molecular mechanisms and neurotherapeutic strategies16
Tumour necrosis factor-α (TNF-α) enhances dietary carcinogen-induced DNA damage in colorectal cancer epithelial cells through activation of JNK signaling pathway16
A deep-learning approach for identifying prospective chemical hazards16
Subacute cadmium exposure promotes M1 macrophage polarization through oxidative stress-evoked inflammatory response and induces porcine adrenal fibrosis16
Acute oral colchicine caused gastric mucosal injury and disturbance of associated microbiota in mice16
Evaluation of toxicological effects of bisphenol S with an in vitro human bone marrow mesenchymal stem cell: Implications for bone health16
Multiomics was used to clarify the mechanism by which air pollutants affect chronic obstructive pulmonary disease: A human cohort study16
Endoplasmic reticulum stress and pro-inflammatory responses induced by phthalate metabolites monoethylhexyl phthalate and monobutyl phthalate in 1.1B4 pancreatic beta cells16
Neurotoxic and convulsant effects induced by jack bean ureases on the mammalian nervous system16
Quercetin protects against levetiracetam induced gonadotoxicity in rats15
Pyriproxyfen exposure induces DNA damage, cell proliferation impairments and apoptosis in the brain vesicles layers of chicken embryos15
The use of calcium carbide in food and fruit ripening: Potential mechanisms of toxicity to humans and future prospects15
Exposure to a combination of MWCNTs and DBP causes splenic toxicity in mice15
Preconception exposure to dibutyl phthalate (DBP) impairs spermatogenesis by activating NF-κB/COX-2/RANKL signaling in Sertoli cells15
Exploring cardiac impact of oral nicotine exposure in a transplantable Neoplasm Mice Model: Insights from biochemical analysis, morphometry, and molecular docking: Chlorella vulgaris green algae suppo15
The impact of legacy and novel perfluoroalkyl substances on human cytochrome P450: An in vitro study on the inhibitory potential and underlying mechanisms15
Why is elevation of serum cholesterol associated with exposure to perfluoroalkyl substances (PFAS) in humans? A workshop report on potential mechanisms15
Exposure to PM2.5 aggravates Parkinson’s disease via inhibition of autophagy and mitophagy pathway15
Acute hydrogen sulfide-induced neurochemical and morphological changes in the brainstem15
Gene expression profiles of two testicular somatic cell lines respond differently to 4-nitrophenol mediating vary reproductive toxicity15
Sodium arsenite accelerates D-galactose-induced aging in the testis of the rat: Evidence for mitochondrial oxidative damage, NF-kB, JNK, and apoptosis pathways15
Bisphenols A, F, S and AF trigger apoptosis and/or endoplasmic reticulum stress in human endometrial stromal cells15
PBDEs and dechlorane plus contamination in community e-waste recycling: Environmental and health implications in Northeastern Thailand14
Ferrostatin‑1 alleviates liver injury via decreasing ferroptosis following ricin toxin poisoning in rat14
Upregulation of postsynaptic cAMP/PKA/CREB signaling alleviates copper(Ⅱ)-induced oxidative stress and pyroptosis in MN9D cells14
Bayesian benchmark dose analysis for inorganic arsenic in drinking water associated with bladder and lung cancer using epidemiological data14
Particulate matter induced cognitive impairments via endoplasmic reticulum stress-mediated damage to mitochondria-associated endoplasmic reticulum membranes in immature rats14
Pesticide mixture effects on liver protein abundance in HepaRG cells14
Corrigendum to “Effects of perinatal exposure to bisphenol A on induction of prostate cancer in Sprague Dawley rats by MNU and testosterone” [Toxicology 484 (2023) 153394]14
Use of a polymeric implant system to assess the neurotoxicity of subacute exposure to 2,2′,5,5′-tetrachlorobiphenyl-4-ol, a human metabolite of PCB 52, in male adolescent rats14
Atrazine impairs testicular function in BalB/c mice by affecting Leydig cells14
Prediction of drug-induced mitochondrial dysfunction using succinate-cytochrome c reductase activity, QSAR and molecular docking14
Corrigendum to: “BPA exposure aggravates necroptosis of myocardial tissue in selenium deficient broilers through NO-dependent endoplasmic reticulum stress” [Toxicology, 472 (2022), 153190]14
Pulmonary toxicity, genotoxicity, and carcinogenicity evaluation of molybdenum, lithium, and tungsten: A review14
Prenatal exposure to di-n-butyl phthalate promotes RIPK1-regulated necroptosis of uroepithelial cells and induces hypospadias through the epithelial-mesenchymal transition process in newborn male rats14
miR-15b-5p promotes HgCl2-induced chicken embryo kidney cells ferroptosis by targeting β-TrCP-mediated ATF4 ubiquitin degradation14
Safety assessment and redox status in rats after chronic exposure to cannabidiol and cannabigerol14
BDE209-promoted Dio2 degradation in H4 glioma cells through the autophagy pathway, resulting in hypothyroidism and leading to neurotoxicity14
Investigating the cardiotoxicity of N-n-butyl haloperidol iodide: Inhibition mechanisms on hERG channels14
O-alkyl and o-benzyl hesperetin derivative-1L attenuates inflammation and protects against alcoholic liver injury via inhibition of BRD2-NF-κB signaling pathway14
Heavy metals altered the xenobiotic metabolism of rats by targeting the GST enzyme: An in vitro and in silico study13
Activation of α7 nicotinic acetylcholine receptor augments nerve growth factor action on PCtrk cells13
Corrigendum to “Investigation of antioxidant, anti-inflammatory and DNA-protective properties of eugenol in thioacetamide-induced liver injury in rats” [Toxicology 268 (3) 204–212]13
Cadmium exposure induces inflammation, oxidative stress and DNA damage in HUVEC and promotes THP-1 adhesion: A possible mechanism on the formation of atherosclerotic plaque13
Infant mice fed soy-based formulas exhibit alterations in anxiety-like behaviours and the 5-HT system13
The challenge to identify sensitive safety biomarkers of peripheral neurotoxicity in the rat: A collaborative effort across industry and academia (IMI NeuroDeRisk project)13
Transcriptomics and metabolomics analyses of graphene oxide toxicity on porcine alveolar macrophages13
Effects of 28-day nose-only inhalation of PCB52 (2,2′,5,5′-Tetrachlorobiphenyl) on the brain transcriptome13
Chronic exposure to polystyrene microplastics induces renal fibrosis via ferroptosis13
Long-term exposure to polystyrene microplastics reduces macrophages and affects the microbiota–gut–brain axis in mice13
Comparative study on gene expression profiles in the liver of male neonatal mice prenatally exposed to PFOA and its alternative HFPO-DA13
Neurotoxic effects and cognitive decline induced by Aniline Blue dye in an in-vivo zebrafish model13
Corrigendum to “Maternal linuron exposure alters testicular development in male offspring rats at the whole genome level” [Toxicology 389 (2017) 13–20]13
Investigation of a broad diversity of nanoparticles, including their processes, as well as toxicity testing in diverse organs and systems13
Substance depletion of volatile monoterpenes – A confounding factor for toxicity testing in the Ames fluctuation test13
Roles of N6-methyladenosine in LncRNA changes and oxidative damage in cadmium-induced pancreatic β-cells13
Chlorpyrifos induces lung metastases and modulation of cancer stem cell markers in triple negative breast cancer model13
COVID-19 and the liver: an adverse outcome pathway perspective13
Susceptibility to DNA damage caused by abrogation of Rad54 homolog B: A putative mechanism for chemically induced cleft palate12
Di-n-butyl phthalate regulates vascular smooth muscle cells phenotypic switching by MiR-139–5p-MYOCD pathways12
Editorial Board Members12
Molecular mechanisms of developmental toxicity induced by BBP in zebrafish embryos12
Cytomodulatory characteristics of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) against cypermethrin on skin fibroblast cells (HFF-1)12
Effects of prenatal pesticide exposure on the fetal brain and placenta transcriptomes in a rodent model12
In vitro toxicity of fibrous glaucophane12
Bisphenol A induces apoptosis in response to DNA damage through c-Abl/YAPY357/ p73 pathway in P19 embryonal carcinoma stem cells12
Sexually concordant and dimorphic transcriptional responses to maternal trichloroethylene and/or N-acetyl cysteine exposure in Wistar rat placental tissue12
Elemicin exposure induced aberrant lipid metabolism via modulation of gut microbiota in mice12
Environmentally relevant perinatal exposure to DBP disturbs testicular development and puberty onset in male mice12
γ-glutamylcysteine suppresses cadmium-induced apoptosis in PC12 cells via regulating oxidative stress12
Editorial Board Members12
The role of mouse and human peroxisome proliferator-activated receptor-α in modulating the hepatic effects of perfluorooctane sulfonate in mice12
In vitro binding analysis of legacy-linear and new generation-cyclic perfluoro-alkyl substances on sex hormone binding globulin and albumin, suggests low impact on serum hormone kinetics of testostero12
Sorafenib is an antagonist of the aryl hydrocarbon receptor12
Toxicity evaluation of particles formed during 3D-printing: Cytotoxic, genotoxic, and inflammatory response in lung and macrophage models12
Comparative toxicities of BPA, BPS, BPF, and TMBPF in the nematode Caenorhabditis elegans and mammalian fibroblast cells12
Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice12
Evidence for enduring cardiac and multiorgan toxicity after repeated exposure to the synthetic cannabinoid JWH-018 in male rats12
Neurotoxicity of Tris (1,3-dichloroisopropyl) phosphate in Caenorhabditis elegans12
Influence of aryl hydrocarbon receptor and sulfotransferase 1A1 on bisphenol AF-induced clastogenesis in human hepatoma cells12
L-tetrahydropalmatine reduces oxaliplatin accumulation in the dorsal root ganglion and mitochondria through selectively inhibiting the transporter-mediated uptake thereby attenuates peripheral neuroto12
Increasing confidence in new approach methodologies for inhalation risk assessment with multiple end point assays using 5-day repeated exposure to 1,3-dichloropropene12
Study on the mechanisms of defective spermatogenesis induced by TiO2 NPs based on 3D blood−testis barrier microfluidic chip12
Adverse effects of microcystins on sperm: A systematic review12
Alterations in reproductive parameters and steroid biosynthesis induced by nickel oxide nanoparticles in male rats: The ameliorative effect of hesperidin12
3D scaffold fabricated with composite material for cell culture and its derived platform for safety evaluation of drugs12
Obituary for Karl Joachim Netter11
The trichothecene neosolaniol stimulates an emetic response through neuropeptide Y2 and serotonin 3 receptors in mink11
Eumelanin protects the liver against diethylnitrosamine-induced liver injury11
11β-hydroxysteroid dehydrogenases and biomarkers in fetal development11
Editorial Board Members11
Dynamics and mechanisms of bioaccumulation and elimination of nonylphenol in zebrafish11
Recreational MDMA doses do not elicit hepatotoxicity in HepG2 spheroids under normo- and hyperthermia11
Transcriptional effects of binary combinations of PFAS in FaO cells11
Editorial Board Members11
Effect of heated tobacco products and traditional cigarettes on pulmonary toxicity and SARS-CoV-2-induced lung injury11
Comparison of the effect of glyphosate and glyphosate-based herbicide on hippocampal neurogenesis after developmental exposure in rats11
A metabolomic approach to study triptolide-induced ovarian damage in rats11
Long-term exposure to arsenic in drinking water leads to myocardial damage by oxidative stress and reduction in NO11
Environmental exposure to microcystin-LR increases the risks of urinary bladder proliferation and carcinogenesis: Evidence from case control, animal, and in vitro studies11
Suppression of apoptotic signaling in rat hepatocytes by non-dioxin-like polychlorinated biphenyls depends on the receptors CAR and PXR11
Ripretinib induced skeletal muscle toxicity through mitochondrial impairment in C2C12 myotubes11
Editorial Board Members11
Editorial Board Members11
Acute and subchronic exposure of cyadox induced metabolic and transcriptomic disturbances in Wistar rats11
Emerging organophosphate ester resorcinol bis(diphenyl phosphate) exerts estrogenic effects via estrogen receptor pathways11
Comparing the effects of polystyrene microplastics exposure on reproduction and fertility in male and female mice10
Wnt5a/Ca2+ signaling regulates silica-induced ferroptosis in mouse macrophages by altering ER stress-mediated redox balance10
A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate®10
Subchronic exposure to di-(2-ethylhexyl) phthalate (DEHP) elicits blood–brain barrier dysfunction and neuroinflammation in male C57BL/6J mice10
Acidosis induces autophagic cell death through ASIC1-mediated Akt/mTOR signaling in HT22 neurons10
A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction10
Chemical effects on neural network activity: Comparison of acute versus network formation exposure in microelectrode array assays10
Association between occupational lead exposure and immunotoxicity markers: A systematic review and meta-analysis10
Random forest algorithm-based accurate prediction of chemical toxicity to Tetrahymena pyriformis10
Necroptosis contributes to airborne particulate matter-induced ocular surface injury10
Environmental mycotoxins: A potential etiological factor for neurodegenerative diseases?10
Sex, age, and species differences of perfluorooctanoic acid modeled by flow- versus permeability-limited physiologically-based pharmacokinetic models10
Hormonal, liver, and renal function associated with electronic waste (e-waste) exposure in Dhaka, Bangladesh10
A workflow to practically apply true dose considerations to in vitro testing for next generation risk assessment10
Gut microbiota dysbiosis and intestinal barrier impairment in diarrhea caused by cold drink and high-fat diet10
Virtual display of targets: A new level to rise the current understanding of ochratoxin A toxicity from a molecular standpoint10
Investigation of the metabolomic crosstalk between liver sinusoidal endothelial cells and hepatocytes exposed to paracetamol using organ-on-chip technology10
Lambda cyhalothrin and chlorantraniliprole caused biochemical, histological, and immunohistochemical alterations in male rabbit liver: Ameliorative effect of vitamins A, D, E, C mixture10
Methamphetamine inhibits huntingtin-associated protein 1-mediated tyrosine receptor kinase B endocytosis resulting the neuroprotective dysfunction of brain-derived neurotrophic factor10
Polyhexamethylene guanidine phosphate induces pyroptosis via reactive oxygen species-regulated mitochondrial dysfunction in bronchial epithelial cells10
Cannabidiol disrupts tryptophan metabolism in the human term placenta10
Loperamide induces excessive accumulation of bile acids in the liver of mice with different diets9
Decabromodiphenyl ether exposure reduces dabrafenib sensitivity of papillary thyroid carcinoma harboring BRAF mutation through the EGFR-CRAF-MAPK pathway: An in vitro study9
Effect of modified citrus pectin on galectin-3 inhibition in cisplatin-induced cardiac and renal toxicity9
Benzo[a]pyrene exposure promotes RIP1-mediated necroptotic death of osteocytes and the JNK/IL-18 pathway activation via generation of reactive oxygen species9
Iodixanol activation of mast cells: Implications in the pathogenesis of iodixanol-induced delayed cutaneous adverse reactions9
Triclosan has a strong influence on the development of mouse preimplantation embryo via activating miR-134/Nanog axis9
Downregulation of miRNA-155–5p contributes to the adipogenic activity of 2-ethylhexyl diphenyl phosphate in 3T3-L1 preadipocytes9
Increased production of matrix metalloproteinase-7 (MMP-7) by asbestos exposure enhances tissue migration of human regulatory T-like cells9
Pulmonary toxicity of molybdenum disulphide after inhalation in mice9
Comparative toxicological analysis of two pristine carbon nanomaterials (graphene oxide and aminated graphene oxide) and their corresponding degraded forms using human in vitro models9
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