Toxicology

Article	Citations
Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats	201
Per- and poly-fluoroalkyl substances (PFAS) and female reproductive outcomes: PFAS elimination, endocrine-mediated effects, and disease	126
Comparing the effects of polystyrene microplastics exposure on reproduction and fertility in male and female mice	115
A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate®	112
Heavy metals induced mitochondrial dysfunction in animals: Molecular mechanism of toxicity	95
Study on the attenuated effect of Ginkgolide B on ferroptosis in high fat diet induced nonalcoholic fatty liver disease	73
Hepatotoxic potentials of methotrexate: Understanding the possible toxicological molecular mechanisms	72
Bioactivity profiling of per- and polyfluoroalkyl substances (PFAS) identifies potential toxicity pathways related to molecular structure	70
NLRP3 inflammasome mediated pyroptosis is involved in cadmium exposure-induced neuroinflammation through the IL-1β/IkB-α-NF-κB-NLRP3 feedback loop in swine	66
The mechanism of the cadmium-induced toxicity and cellular response in the liver	54
Polystyrene nanoplastics dysregulate lipid metabolism in murine macrophages in vitro	54
Resveratrol protected acrolein-induced ferroptosis and insulin secretion dysfunction via ER-stress- related PERK pathway in MIN6 cells	54
Why is elevation of serum cholesterol associated with exposure to perfluoroalkyl substances (PFAS) in humans? A workshop report on potential mechanisms	49
AHR/ROS-mediated mitochondria apoptosis contributes to benzo[a]pyrene-induced heart defects and the protective effects of resveratrol	49
Effect of uncontrolled fertilization and heavy metal toxicity associated with arsenic(As), lead(Pb) and cadmium (Cd), and possible remediation	48
Persistent activation of Nrf2 promotes a vicious cycle of oxidative stress and autophagy inhibition in cadmium-induced kidney injury	45
Vipers of Major clinical relevance in Europe: Taxonomy, venom composition, toxicology and clinical management of human bites	43
Safer chemicals using less animals: kick-off of the European ONTOX project	42
Paraquat exposure over generation affects lifespan and reproduction through mitochondrial disruption in C. elegans	41
Exposure to a mixture of heavy metals induces cognitive impairment: Genes and microRNAs involved	38
ROS and iron homeostasis dependent ferroptosis play a vital role in 5-Fluorouracil induced cardiotoxicity in vitro and in vivo	38
Environmental and occupational pesticide exposure and human sperm parameters: A Navigation Guide review	37
Phosgene inhalation toxicity: Update on mechanisms and mechanism-based treatment strategies	37
Aspirin eugenol ester ameliorates paraquat-induced oxidative damage through ROS/p38-MAPK-mediated mitochondrial apoptosis pathway	37
Nutrition, one-carbon metabolism and arsenic methylation	36

Oxaliplatin-induced hepatic sinusoidal obstruction syndrome	35
Inhibition of ferroptosis reduces susceptibility to frequent excessive alcohol consumption-induced atrial fibrillation	35
Oxidative stress-dependent frataxin inhibition mediated alcoholic hepatocytotoxicity through ferroptosis	35
Characterization of application scenario-dependent pharmacokinetics and pharmacodynamic properties of permethrin and hyperforin in a dynamic skin and liver multi-organ-chip model	35
Ozone exposure promotes pyroptosis in rat lungs via the TLR2/4-NF-κB-NLRP3 signaling pathway	34
Mechanisms and treatment strategies of organophosphate pesticide induced neurotoxicity in humans: A critical appraisal	34
Alternative animal models in predictive toxicology	34
Cadmium induces endoplasmic reticulum stress-mediated apoptosis in pig pancreas via the increase of Th1 cells	33
Exposure to PM2.5 aggravates Parkinson’s disease via inhibition of autophagy and mitophagy pathway	33
Apoptotic activities of brusatol in human non-small cell lung cancer cells: Involvement of ROS-mediated mitochondrial-dependent pathway and inhibition of Nrf2-mediated antioxidant response	33
Cadmium induces apoptosis via generating reactive oxygen species to activate mitochondrial p53 pathway in primary rat osteoblasts	33
Metabolic, reproductive and thyroid effects of bis(2-ethylhexyl) phthalate (DEHP) orally administered to male and female juvenile rats at dose levels derived from children biomonitoring study	31
Arsenic methylation – Lessons from three decades of research	31
Cadmium exposure induces TNF-α-mediated necroptosis via FPR2/TGF-β/NF-κB pathway in swine myocardium	31
Polystyrene nanoplastics exacerbate lipopolysaccharide-induced myocardial fibrosis and autophagy in mice via ROS/TGF-β1/Smad	30
Nicotine stimulates IL-8 expression via ROS/NF-κB and ROS/MAPK/AP-1 axis in human gastric cancer cells	30
Benzo[a]pyrene immunogenetics and immune archetype reprogramming of lung	30
SIRT4 Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the AKT/mTOR/Autophagy Pathway	30
Glyphosate-based herbicides: Evidence of immune-endocrine alteration	30
Investigating the cytotoxicity of per- and polyfluoroalkyl substances in HepG2 cells: A structure-activity relationship approach	30
Human in vitro vascularized micro-organ and micro-tumor models are reproducible organ-on-a-chip platforms for studies of anticancer drugs	29
Adipose mesenchymal stem cell-derived antioxidative extracellular vesicles exhibit anti-oxidative stress and immunomodulatory effects under PM2.5 exposure	29
Environmental pollutants exposure and male reproductive toxicity: The role of epigenetic modifications	29
Mitochondria damage and ferroptosis involved in Ni-induced hepatotoxicity in mice	29
Cigarette smoking exposure breaks the homeostasis of cholesterol and bile acid metabolism and induces gut microbiota dysbiosis in mice with different diets	29
Lead (Pb) induced Oxidative Stress as a Mechanism to Cause Neurotoxicity in Drosophila melanogaster	28
Analysis of reproducibility and robustness of a human microfluidic four-cell liver acinus microphysiology system (LAMPS)	28
In-vitro toxicity of molybdenum trioxide nanoparticles on human keratinocytes	27
Multiple neurological effects associated with exposure to organophosphorus pesticides in man	27
Molecular toxicity of methotrexate in rheumatoid arthritis treatment: A novel perspective and therapeutic implications	27
Derivation, characterisation and analysis of an adverse outcome pathway network for human hepatotoxicity	26
Bayesian benchmark dose analysis for inorganic arsenic in drinking water associated with bladder and lung cancer using epidemiological data	26
Cytotoxicity and genotoxicity of low-dose vanadium dioxide nanoparticles to lung cells following long-term exposure	26
Central role of TRAP1 in the ameliorative effect of oleanolic acid on the mitochondrial-mediated and endoplasmic reticulum stress-excitated apoptosis induced by ochratoxin A	26
The use of calcium carbide in food and fruit ripening: Potential mechanisms of toxicity to humans and future prospects	26
Health repercussions of environmental exposure to lead: Methylation perspective	25
Perfluorooctane sulfonate (PFOS) disrupts testosterone biosynthesis via CREB/CRTC2/StAR signaling pathway in Leydig cells	25
Dual TBK1/IKKε inhibitor amlexanox mitigates palmitic acid-induced hepatotoxicity and lipoapoptosis in vitro	25
Ubiquitous plasticizer, Di-(2-ethylhexyl) phthalate enhances existing inflammatory profile in monocytes of children with autism	25
Microphysiological system modeling of ochratoxin A-associated nephrotoxicity	25
Comparative toxicities of BPA, BPS, BPF, and TMBPF in the nematode Caenorhabditis elegans and mammalian fibroblast cells	24
Salidroside alleviates liver inflammation in furan-induced mice by regulating oxidative stress and endoplasmic reticulum stress	24
Nanosafety vs. nanotoxicology: adequate animal models for testing in vivo toxicity of nanoparticles	24
Subacute cadmium exposure promotes M1 macrophage polarization through oxidative stress-evoked inflammatory response and induces porcine adrenal fibrosis	24
Roles of ERK/Akt signals in mitochondria-dependent and endoplasmic reticulum stress-triggered neuronal cell apoptosis induced by 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, a major active metabolite	23
Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies	23
Atrazine impairs testicular function in BalB/c mice by affecting Leydig cells	23
Formaldehyde induces ferroptosis in hippocampal neuronal cells by upregulation of the Warburg effect	23
Selenium triggers Nrf2-AMPK crosstalk to alleviate cadmium-induced autophagy in rabbit cerebrum	23
Pulmonary toxicity, genotoxicity, and carcinogenicity evaluation of molybdenum, lithium, and tungsten: A review	23

Structure-activity relationship analysis of perfluoroalkyl carbonic acids on human and rat placental 3β-hydroxysteroid dehydrogenase activity	23
Ustilaginoidin D induces hepatotoxicity and behaviour aberrations in zebrafish larvae	23
A review of low-dose arsenic risks and human cancers	22
Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity	22
Cannabidiol selectively modulates interleukin (IL)-1β and IL-6 production in toll-like receptor activated human peripheral blood monocytes	22
The impact of legacy and novel perfluoroalkyl substances on human cytochrome P450: An in vitro study on the inhibitory potential and underlying mechanisms	22
Aflatoxin B1 interferes with embryonic liver development: Involvement of p53 signaling and apoptosis in zebrafish	22
Bisphenol S promotes the progression of prostate cancer by regulating the expression of COL1A1 and COL1A2	22
Di-(2-ethyl hexyl) phthalate induced oxidative stress promotes microplastics mediated apoptosis and necroptosis in mice skeletal muscle by inhibiting PI3K/AKT/mTOR pathway	21
Relative comparison of strobilurin fungicides at environmental levels: Focus on mitochondrial function and larval activity in early staged zebrafish (Danio rerio)	21
Protective effects of Folic acid against reproductive, hematological, hepatic, and renal toxicity induced by Acetamiprid in male Albino rats	21
Zearalenone exposure mediated hepatotoxicity via mitochondrial apoptotic and autophagy pathways: Associated with gut microbiome and metabolites	21
Cadmium disrupts mitochondrial distribution and activates excessive mitochondrial fission by elevating cytosolic calcium independent of MCU-mediated mitochondrial calcium uptake in its neurotoxicity	21
Environmental factors modulating protein conformations and their role in protein aggregation diseases	21
Cadmium induces apoptosis of pig lymph nodes by regulating the PI3K/AKT/HIF-1α pathway	20
Prenatal dexamethasone exposure caused fetal rats liver dysplasia by inhibiting autophagy-mediated cell proliferation	20
A comparative study based on activity, conformation and computational analysis on the inhibition of human salivary aldehyde dehydrogenase by phthalate plasticizers: Implications in assessing the safet	20
Polystyrene microplastics induced oxidative stress, inflammation and necroptosis via NF-κB and RIP1/RIP3/MLKL pathway in chicken kidney	20
Per- and polyfluoroalkyl substances (PFAS) augment adipogenesis and shift the proteome in murine 3T3-L1 adipocytes	20
PKM2 regulates cigarette smoke-induced airway inflammation and epithelial-to-mesenchymal transition via modulating PINK1/Parkin-mediated mitophagy	20
Chronic ethanol exposure induces neuroinflammation in H4 cells through TLR3 / NF-κB pathway and anxiety-like behavior in male C57BL/6 mice	20
Comparative cytotoxicity of seven per- and polyfluoroalkyl substances (PFAS) in six human cell lines	19
The role of maternal high fat diet on mouse pup metabolic endpoints following perinatal PFAS and PFAS mixture exposure	19
Predicting the effects of per- and polyfluoroalkyl substance mixtures on peroxisome proliferator-activated receptor alpha activity in vitro	19
Effects of phthalates on the functions and fertility of mouse spermatozoa	19
Phytosphingosine-induced cell apoptosis via a mitochondrially mediated pathway	19
Exploring the aging effect of the anticancer drugs doxorubicin and mitoxantrone on cardiac mitochondrial proteome using a murine model	19
The effects of bisphenol A and bisphenol S on adipokine expression and glucose metabolism in human adipose tissue	19
The effects of cadmium on the development of Drosophila and its transgenerational inheritance effects	19
Changes induced by chronic exposure to high arsenic concentrations in the intestine and its microenvironment	19
Chronic consumption of food-additives lead to changes via microbiota gut-brain axis	19
Nutrient molecule corona: An update for nanomaterial-food component interactions	19
Cadmium-stimulated invasion of rat liver cells during malignant transformation: Evidence of the involvement of oxidative stress/TET1-sensitive machinery	18
A hypoxia-driven occurrence of chronic kidney disease and osteoporosis in COPD individuals: New insights into environmental cadmium exposure	18
Bisphenol A exposure prenatally delays bone development and bone mass accumulation in female rat offspring via the ERβ/HDAC5/TGFβ signaling pathway	18
Comparison of quantitation methods in proteomics to define relevant toxicological information on AhR activation of HepG2 cells by BaP	18
Involvement of CYP2E1-ROS-CD36/DGAT2 axis in the pathogenesis of VPA-induced hepatic steatosis in vivo and in vitro	18
Perfluorooctane sulfonate (PFOS) exposure of bovine oocytes affects early embryonic development at human-relevant levels in an in vitro model	18
3-Indolepropionic acid upturned male reproductive function by reducing oxido-inflammatory responses and apoptosis along the hypothalamic-pituitary-gonadal axis of adult rats exposed to chlorpyrifos	18
Molecular mechanism of kidney damage caused by abamectin in carp: Oxidative stress, inflammation, mitochondrial damage, and apoptosis	18
Prepubertal arsenic exposure alters phosphoproteins profile, quality, and fertility of epididymal spermatozoa in sexually mature rats	18
Reproducibility of adipogenic responses to metabolism disrupting chemicals in the 3T3-L1 pre-adipocyte model system: An interlaboratory study	18
Pterostilbene attenuates RIPK3-dependent hepatocyte necroptosis in alcoholic liver disease via SIRT2-mediated NFATc4 deacetylation	18
The methylimidazolium ionic liquid M8OI is detectable in human sera and is subject to biliary excretion in perfused human liver	17
Cyclophosphamide instigated hepatic-renal oxidative/inflammatory stress aggravates immunosuppressive indoleamine 2,3-dioxygenase in male rats: Abatement by quercetin	17
Redox-sensitive Nrf2 and MAPK signaling pathways contribute to trichloroethene-mediated autoimmune disease progression	17
Cigarette smoke extract reduces FOXO3a promoting tumor progression and cell migration in lung cancer	17
Perfluoroheptanoic acid induces Leydig cell hyperplasia but inhibits spermatogenesis in rats after pubertal exposure	17
The dynamicity of acute ozone-induced systemic leukocyte trafficking and adrenal-derived stress hormones	17
Effects of low dose ionizing radiation on the brain- a functional, cellular, and molecular perspective	17
Polybrominated diphenyl ethers quinone exhibits neurotoxicity by inducing DNA damage, cell cycle arrest, apoptosis and p53-driven adaptive response in microglia BV2 cells	17
Impaired mitochondrial function of alveolar macrophages in carbon nanotube-induced chronic pulmonary granulomatous disease	17
METTL3-mediated M6A methylation modification is involved in colistin-induced nephrotoxicity through apoptosis mediated by Keap1/Nrf2 signaling pathway	16
The combined impact of decabromodiphenyl ether and high fat exposure on non-alcoholic fatty liver disease in vivo and in vitro	16
Iron overload inhibits cell proliferation and promotes autophagy via PARP1/SIRT1 signaling in endometriosis and adenomyosis	16
Phosphocreatine attenuates doxorubicin-induced cardiotoxicity by inhibiting oxidative stress and activating TAK1 to promote myocardial survival in vivo and in vitro	16
Interleukin 33 mediates hepatocyte autophagy and innate immune response in the early phase of acetaminophen-induced acute liver injury	16
Developmental toxicity of fenbuconazole in zebrafish: Effects on mitochondrial respiration and locomotor behavior	16
Non-cytotoxic dosage of fumonisin B1 aggravates ochratoxin A-induced nephrocytotoxicity and apoptosis via ROS-dependent JNK/MAPK signaling pathway	16
Cadmium acute exposure induces metabolic and transcriptomic perturbations in human mature adipocytes	16
PM2.5 induces mitochondrial dysfunction via AHR-mediated cyp1a1 overexpression during zebrafish heart development	16
Involvement of ABC transporters in the detoxification of non-substrate nanoparticles in lung and cervical cancer cells	16
Multiple metabolic changes mediate the response of Caenorhabditis elegans to the complex I inhibitor rotenone	16
Research update on aflatoxins toxicity, metabolism, distribution, and detection: A concise overview	15
BDE-209 induce spermatocytes arrest at early-pachytene stage during meiotic prophase I in mice	15
The immune modulatory role of marjoram extract on imidacloprid induced toxic effects in thymus and spleen of adult rats	15
Cytotoxicity and pro-inflammatory effect of polystyrene nano-plastic and micro-plastic on RAW264.7 cells	15
Bisphenol-A exposure leads to neurotoxicity through upregulating the expression of histone deacetylase 2 in vivo and in vitro	15
Bisphenols A, F, S and AF trigger apoptosis and/or endoplasmic reticulum stress in human endometrial stromal cells	15
Endocrine disrupting chemicals: Friend or foe to brown and beige adipose tissue?	15
Inhalation exposure by cigarette smoke: Effects on the progression of bleomycin- and lipopolysaccharide-induced lung injuries in rat models	15
MicroRNA-223–3p promotes pyroptosis of cardiomyocyte and release of inflammasome factors via downregulating the expression level of SPI1 (PU.1)	15
Surface modification of pralidoxime chloride-loaded solid lipid nanoparticles for enhanced brain reactivation of organophosphorus-inhibited AChE: Pharmacokinetics in rat	15
Tumour necrosis factor-α (TNF-α) enhances dietary carcinogen-induced DNA damage in colorectal cancer epithelial cells through activation of JNK signaling pathway	15
Human-relevant mechanisms and risk factors for TAK-875-Induced liver injury identified via a gene pathway-based approach in Collaborative Cross mice	15
Perfluoroalkyl acids potentiate glutamate excitotoxicity in rat cerebellar granule neurons	15
GenX induces fibroinflammatory gene expression in primary human hepatocytes	15
Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent	15
Association of endocrine disrupting chemicals levels in serum, environmental risk factors, and hepatic function among 5- to 14-year-old children	15
Zinc and selenium mitigated heavy metals mixture (Pb, Al, Hg and Mn) mediated hepatic-nephropathy via modulation of oxido-inflammatory status and NF‑kB signaling in female albino rats	14

TCDD attenuates EAE through induction of FasL on B cells and inhibition of IgG production	14
Microcystin-leucine arginine exposure induced intestinal lipid accumulation and MC-LR efflux disorder in Lithobates catesbeianus tadpoles	14
C. elegans toxicant responses vary among genetically diverse individuals	14
Sodium arsenite accelerates D-galactose-induced aging in the testis of the rat: Evidence for mitochondrial oxidative damage, NF-kB, JNK, and apoptosis pathways	14
Aryl hydrocarbon receptor as a DNA methylation reader in the stress response pathway	14
The aryl hydrocarbon receptor activates ceramide biosynthesis in mice contributing to hepatic lipogenesis	14
Development and characterization of rat duodenal organoids for ADME and toxicology applications	14
Close association between the synergistic toxicity of zearalenone-deoxynivalenol combination and microRNA221-mediated PTEN/PI3K/AKT signaling in HepG2 cells	14
Perinatal exposure to a glyphosate-based herbicide causes dysregulation of dynorphins and an increase of neural precursor cells in the brain of adult male rats	14
Assessing the neurotoxicity of the carbamate methomyl in Caenorhabditis elegans with a multi-level approach	14
Chronic exposure of bisphenol-A impairs cognitive function and disrupts hippocampal insulin signaling pathway in male mice	14
Long noncoding RNA-SNHG20 promotes silica-induced pulmonary fibrosis by miR-490-3p/TGFBR1 axis	14
The potential mechanism of histamine-inducing cardiopulmonary inflammation and apoptosis in a novel oral model of rat intoxication	14
Exosomes mediated the delivery of ochratoxin A-induced cytotoxicity in HEK293 cells	14
Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice	14
The role of DRP1- PINK1-Parkin-mediated mitophagy in early cadmium-induced liver damage	14
Hematological consequences of polyethylene microplastics toxicity in male rats: Oxidative stress, genetic, and epigenetic links	14
Enantioselective toxic effects of mefentrifluconazole in the liver of adult zebrafish (Danio rerio) based on transcription level and metabolomic profile	13
Melatonin ameliorates nickel induced autophagy in mouse brain: Diminution of oxidative stress	13
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis	13
Toxicity evaluation of particles formed during 3D-printing: Cytotoxic, genotoxic, and inflammatory response in lung and macrophage models	13
Autophagy-induced p62 accumulation is required for curcumol to regulate KLF5-mediated angiogenesis in liver sinusoidal endothelial cells	13
Identifying the link between chemical exposures and breast cancer in African American women via integrated in vitro and exposure biomarker data	13
Cardioprotective effects of bosentan in 5-fluorouracil-induced cardiotoxicity	13
Innovation in drug toxicology: Application of mass spectrometry imaging technology	13
Environmentally relevant perinatal exposure to DBP disturbs testicular development and puberty onset in male mice	13
Hsa_circ_0005915 promotes N,N-dimethylformamide-induced oxidative stress in HL-7702 cells through NRF2/ARE axis	13
Alterations in reproductive parameters and steroid biosynthesis induced by nickel oxide nanoparticles in male rats: The ameliorative effect of hesperidin	13
An adverse outcome pathway on the disruption of retinoic acid metabolism leading to developmental craniofacial defects	13
Cellular response of THP-1 macrophages to polystyrene microplastics exposure	13
HIF-1α inhibits T-2 toxin-mediated "immune evasion" process by negatively regulating PD-1/PD-L1	13
Random forest algorithm-based accurate prediction of chemical toxicity to Tetrahymena pyriformis	13
miR-138 inhibits epithelial-mesenchymal transition in silica-induced pulmonary fibrosis by regulating ZEB2	13
Inhalation toxicity of copper compounds: Results of 14-day range finding study for copper sulphate pentahydrate and dicopper oxide and 28-day subacute inhalation exposure of dicopper oxide in rats	12
L-carnitine extenuates endocrine disruption, inflammatory burst and oxidative stress in carbendazim-challenged male rats via upregulation of testicular StAR and FABP9, and downregulation of P38-MAPK p	12
Evaluation and comparison of in vitro intrinsic clearance rates measured using cryopreserved hepatocytes from humans, rats, and rainbow trout	12
NaF-induced neurotoxicity via activation of the IL-1β/JNK signaling pathway	12
Physiologically inspired culture medium prolongs the lifetime and insulin sensitivity of human hepatocytes in micropatterned co-cultures	12
In vitro toxicity of fibrous glaucophane	12
Phenanthrene induces autism-like behavior by promoting oxidative stress and mTOR pathway activation	12
Exposure to a combination of MWCNTs and DBP causes splenic toxicity in mice	12
Estragole: DNA adduct formation in primary rat hepatocytes and genotoxic potential in HepG2-CYP1A2 cells	12
Perinatal exposure to known endocrine disrupters alters ovarian development and systemic steroid hormone profile in rats	12
Toxicity mechanism of acrolein on DNA damage and apoptosis in BEAS-2B cells: Insights from cell biology and molecular docking analyses	12
Genotoxicity assessment of per- and polyfluoroalkyl substances mixtures in human liver cells (HepG2)	12
NAM-based prediction of point-of-contact toxicity in the lung: A case example with 1,3-dichloropropene	12
Essential concepts for interpreting the dose-response of low-level arsenic exposure in epidemiological studies	12
Synergistic effects of arsenic and fluoride on oxidative stress and apoptotic pathway in Leydig and Sertoli cells	12
Arsenic exposure during porcine oocyte maturation negatively affects embryonic development by triggering oxidative stress-induced mitochondrial dysfunction and apoptosis	12
L-tetrahydropalmatine reduces oxaliplatin accumulation in the dorsal root ganglion and mitochondria through selectively inhibiting the transporter-mediated uptake thereby attenuates peripheral neuroto	12
Cytotoxicity and mechanism of action of metal complexes: An overview	12
O-alkyl and o-benzyl hesperetin derivative-1L attenuates inflammation and protects against alcoholic liver injury via inhibition of BRD2-NF-κB signaling pathway	12
Single intratracheal administration of cross-linked water-soluble acrylic acid polymer causes acute alveolo-interstitial inflammation and the subsequent fibrotic formation possibly via the TGF-β1 path	12
The role of α5-nicotinic acetylcholine receptor/NLRP3 signaling pathway in lung adenocarcinoma cell proliferation and migration	12
Identification of miRNAs involved in liver injury induced by chronic exposure to cadmium	12
Potential mechanism of lead poisoning to the growth and development of ovarian follicle	12
Protective effects of resveratrol against the cardiac developmental toxicity of trichloroethylene in zebrafish embryos	12
Effects of endocrine disrupting chemicals on the expression of RACK1 and LPS-induced THP-1 cell activation	12
Neurotoxicity of zearalenone’s metabolites and beauvericin mycotoxins via apoptosis and cell cycle disruption	12
Acute oral colchicine caused gastric mucosal injury and disturbance of associated microbiota in mice	12
Prediction of drug-induced mitochondrial dysfunction using succinate-cytochrome c reductase activity, QSAR and molecular docking	12
An integrated approach, based on mass spectrometry, for the assessment of imidacloprid metabolism and penetration into mouse brain and fetus after oral treatment	12
Evidence for the systemic diffusion of (2-chloroethyl)-ethyl-sulfide, a sulfur mustard analog, and its deleterious effects in brain	12
Improvement roles of zinc supplementation in low dose lead induced testicular damage and glycolytic inhibition in mice	12
Curcumin alleviates aristolochic acid nephropathy based on SIRT1/Nrf2/HO-1 signaling pathway	11
Alginic acid induces oxidative stress-mediated hormone secretion disorder, apoptosis and autophagy in mouse granulosa cells and ovaries	11
Nano-enabled delivery of EGCG ameliorates silica-induced pulmonary fibrosis in rats	11
Immunosuppression characterized by increased Treg cell and IL-10 levels in benzene-induced hematopoietic toxicity mouse model	11
Effects of all-trans and 9-cis retinoic acid on differentiating human neural stem cells in vitro	11
Necroptosis contributes to airborne particulate matter-induced ocular surface injury	11
Acute cytotoxicity of mineral fibres observed by time-lapse video microscopy	11
TSSF-hERG: A machine-learning-based hERG potassium channel-specific scoring function for chemical cardiotoxicity prediction	11
RNA-Seq approach to investigate the effects of melatonin on bone marrow-derived dendritic cells from dextran sodium sulfate-induced colitis mice	11
Radiation-induced lipoprotein-associated phospholipase A2 increases lysophosphatidylcholine and induces endothelial cell damage	11
Acute acrylonitrile exposure inhibits endogenous H2S biosynthesis in rat brain and liver: The role of CBS/3-MPST-H2S pathway in its astrocytic toxicity	11
Acrolein inhalation acutely affects the regulation of mitochondrial metabolism in rat lung	11
BPA exposure aggravates necroptosis of myocardial tissue in selenium deficient broilers through NO-dependent endoplasmic reticulum stress	11
Di-n-butyl phthalate regulates vascular smooth muscle cells phenotypic switching by MiR-139–5p-MYOCD pathways	11
The potential risks of chronic fluoride exposure on nephrotoxic via altering glucolipid metabolism and activating autophagy and apoptosis in ducks	11
Silibinin-loaded nanostructured lipid carriers (NLCs) ameliorated cognitive deficits and oxidative damages in aluminum chloride-induced neurotoxicity in male mice	11
Octocrylene exposure impairs mouse oocyte quality by inducing spindle defects and mitochondria dysfunction	11
The effects of carbon monoxide releasing molecules on paraquat-induced pulmonary interstitial inflammation and fibrosis	11
In utero exposures to mint-flavored JUUL aerosol impair lung development and aggravate house dust mite-induced asthma in adult offspring mice	11
Gut as the target tissue of mercury and the extraintestinal effects	11
Prenatal exposure to phthalates and its effects upon cognitive and motor functions: A systematic review	11
Association between occupational lead exposure and immunotoxicity markers: A systematic review and meta-analysis	11
Enhanced GRP78 protein expression via the IRE1α/ASK1/p38 MAPK pathway during As2O3-induced endoplasmic reticulum stress in BEAS-2B cells	10
Cyanotoxin exposure and hepatocellular carcinoma	10
Causal relationship between humidifier disinfectant exposure and Th17-mediated airway inflammation and hyperresponsiveness	10
COVID-19 and the liver: an adverse outcome pathway perspective	10
Cadmium induced mouse spermatogonia apoptosis via mitochondrial calcium overload mediated by IP3R-MCU signal pathway	10
Tauroursodeoxycholic acid attenuates cisplatin-induced ototoxicity by inhibiting the accumulation and aggregation of unfolded or misfolded proteins in the endoplasmic reticulum	10
Effects of lanthanum nitrate on behavioral disorder, neuronal damage and gene expression in different developmental stages of Caenorhabditis elegans	10
Upregulation of postsynaptic cAMP/PKA/CREB signaling alleviates copper(Ⅱ)-induced oxidative stress and pyroptosis in MN9D cells	10
Human 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure and thyroid cancer risk	10