OOIR: Observatory of International Research

Papers

(The H4-Index of Toxicology is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Early life exposure to per- and polyfluoroalkyl substances (PFAS) and latent health outcomes: A review including the placenta as a target tissue and possible driver of peri- and postnatal effects	210
Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats	158
A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate®	90
Per- and poly-fluoroalkyl substances (PFAS) and female reproductive outcomes: PFAS elimination, endocrine-mediated effects, and disease	89
Comparing the effects of polystyrene microplastics exposure on reproduction and fertility in male and female mice	76
Heavy metals induced mitochondrial dysfunction in animals: Molecular mechanism of toxicity	69
Study on the attenuated effect of Ginkgolide B on ferroptosis in high fat diet induced nonalcoholic fatty liver disease	61
Inhibition of ferroptosis attenuates busulfan-induced oligospermia in mice	60
NLRP3 inflammasome mediated pyroptosis is involved in cadmium exposure-induced neuroinflammation through the IL-1β/IkB-α-NF-κB-NLRP3 feedback loop in swine	58
Bioactivity profiling of per- and polyfluoroalkyl substances (PFAS) identifies potential toxicity pathways related to molecular structure	57
Hepatotoxic potentials of methotrexate: Understanding the possible toxicological molecular mechanisms	54
Polystyrene nanoplastics dysregulate lipid metabolism in murine macrophages in vitro	43
Why is elevation of serum cholesterol associated with exposure to perfluoroalkyl substances (PFAS) in humans? A workshop report on potential mechanisms	41
Persistent activation of Nrf2 promotes a vicious cycle of oxidative stress and autophagy inhibition in cadmium-induced kidney injury	41
Resveratrol protected acrolein-induced ferroptosis and insulin secretion dysfunction via ER-stress- related PERK pathway in MIN6 cells	41
The mechanism of the cadmium-induced toxicity and cellular response in the liver	36
AHR/ROS-mediated mitochondria apoptosis contributes to benzo[a]pyrene-induced heart defects and the protective effects of resveratrol	36
The neuroprotective effect of curcumin against Cd-induced neurotoxicity and hippocampal neurogenesis promotion through CREB-BDNF signaling pathway	36
Effects and mechanisms of pyrethroids on male reproductive system	35
The way forward for assessing the human health safety of cosmetics in the EU - Workshop proceedings	34
Aspirin eugenol ester ameliorates paraquat-induced oxidative damage through ROS/p38-MAPK-mediated mitochondrial apoptosis pathway	33
Protocatechuic acid modulates reproductive dysfunction linked to furan exposure in rats	33
Vipers of Major clinical relevance in Europe: Taxonomy, venom composition, toxicology and clinical management of human bites	33
Oxidative stress-dependent frataxin inhibition mediated alcoholic hepatocytotoxicity through ferroptosis	32
Paraquat exposure over generation affects lifespan and reproduction through mitochondrial disruption in C. elegans	32

Safer chemicals using less animals: kick-off of the European ONTOX project	32
Characterization of application scenario-dependent pharmacokinetics and pharmacodynamic properties of permethrin and hyperforin in a dynamic skin and liver multi-organ-chip model	32
ROS and iron homeostasis dependent ferroptosis play a vital role in 5-Fluorouracil induced cardiotoxicity in vitro and in vivo	32
Omeprazole attenuates cisplatin-induced kidney injury through suppression of the TLR4/NF-κB/NLRP3 signaling pathway	31
Phosgene inhalation toxicity: Update on mechanisms and mechanism-based treatment strategies	31
Exposure to a mixture of heavy metals induces cognitive impairment: Genes and microRNAs involved	31