OOIR: Observatory of International Research

Papers

(The TQCC of Rhinology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
The alchemy of precision and innovation: treating chronic airway inflammatory conditions in 2025	173
Nasal endoscopy score thresholds to trigger consideration of chronic rhinosinusitis treatment escalation and implications for disease control	159
Regional disparities in cost-effectiveness of biologics for CRSwNP should not modify the strategy	64
Relationship of chronic rhinosinusitis with Sjögren’s syndrome, systemic lupus erythematosus, and ankylosing spondylitis	38
Endoscopic surgery versus conservative treatment in nasopharyngeal carcinoma patients with nasopharyngeal necrosis	33
Microbiome analyses in chronic rhinosinusitis	29
Correlations of pre- and post-operative symptoms with cytokines in different phenotypes and endotypes of chronic rhinosinusitis	23
Elevated MIF identified by multiple cytokine analyses facilitates macrophage M2 polarization contributing to postoperative recurrence in chronic rhinosinusitis with nasal polyps	21
Reply to Letter to the editor concerning "Determining a cut-off value for eosinophilic chronic rhinosinusitis"	19
Characterization of the ciliary beating efficiency in primary diffuse chronic rhinosinusitis	15
Rhino(septo)plasty Informed Consent Consensus by the European Rhinoplasty Course Faculty – EUFOREA	15
Body mass index’s effect on CRSwNP extends to pathological endotype and recurrence	12
Reconsidering biologic treatment recommendations for CRSwNP without asthma in EUFOREA guidelines	12
Exhaled breath condensate metabolomics reveals conserved networks and bidirectional crosstalk in asthma and CRSwNP	11
Salvage endoscopic surgery for skull base osteoradionecrosis in nasopharyngeal carcinoma patients: A prospective, observational, single-arm clinical study	11
Real-world observational data on olfactory dysfunction of the Smell & Taste Clinic of UZ Leuven (Belgium) from 2021-2024	11
Motion analysis for objective evaluation of psychomotor skills in Endoscopic Sinus Surgery	10
High-HDAC7 expression related to poor prognosis in sinonasal mucosal melanoma	10
Blood eosinophils to direct oral corticosteroid treatment for patients with nasal polyps – an open label, non-inferiority, randomized control trial	9
The differences between sinonasal respiratory epithelial adenomatoid hamartoma and nasal polyps: insights into immunopathology	9
Critical appraisal of methodological rigor in a systematic review on post-COVID-19 vaccination-associated olfactory dysfunction	9
Tissue eosinophilia and computed tomography features in paediatric chronic rhinosinusitis with nasal polyps requiring revision surgery	9
Clinical management of dupilumab-induced blood eosinophilia in CRSwNP: a practical algorithm	9
Impact of real-world confounders on the accuracy of an AI model to support read out of skin prick automated test results	9
Local IgE is a superior biomarker than serum IgE for nasal type 2 inflammation in house dust mites sensitized allergic rhinitis	8

Targeted biologics for chronic rhinosinusitis with nasal polyps: efficacy and safety comparison of eight monoclonal antibodies via network meta-analysis	8
Topical corticosteroids adherence in chronic rhinosinusitis with nasal polyps patients on dupilumab	8
Effectiveness of the lateral pedicled endonasal flap for prevention of restenosis in frontal sinus drillouts	7
Development and psychometric validation of the Chronic Rhinosinusitis Control Test	7
Type 2 inflammation promotes distinct metabolic profiles in chronic rhinosinusitis with nasal polyps	7
Association between allergic rhinitis and attention deficit hyperactivity disorder symptoms in pediatric patients: the impact of seasonal variability	7
Gender differences in outcomes following endoscopic sinus surgery: a systematic review and meta-analysis	7
Concomitant cystic fibrosis and NSAID-exacerbated respiratory disease	7
Topical anaesthesia and decongestion in rhinology	6
The use of fascia lata can minimize olfactory damage in endoscopic endonasal skull base surgery	6
Patients with olfactory loss exhibit pronounced adaptation to chemosensory stimuli: an electrophysiological study	6
Variations of olfactory function with circadian timing and chronotype	6
Predictive factors of involuntary weight loss in patients with smell and taste disorders	6
A positive correlation between autonomic nervous system function and endoscopic disease severity in chronic rhinosinusitis: a quantitative assessment	6
Establishing validity of a novel patient-centered and directly measurable definition of acute exacerbation of chronic rhinosinusitis	5
Discordance of chronic rhinosinusitis disease control between EPOS guidelines and patient perspectives identifies utility of patient-rated control assessment	5
Association of gustatory dysfunction and Alzheimer's disease: a systematic review and meta-analysis	5
Indication for biologics in a real-world cohort of dupilumab treated chronic rhinosinusitis with nasal polyps patients according to international recommendations: evidence from the European CRS Outcom	5
Measuring control of disease in Chronic Rhinosinusitis; assessing the correlation between SinoNasal Outcome Test-22 and Visual Analogue Scale item scores	5
Nasal disorders and cardiovascular damage: flow-mediated dilation and intima-media thickness as risk parameters	5
From persistent olfactory dysfunction to permanent loss: investigating quality of life in acquired and congenital anosmia	5
Comment to the article "Comparison of outcomes for Draf IIB vs Draf III in endoscopic frontal sinus surgery: a comprehensive systematic review and meta-analysis"	4
Mepolizumab improves outcomes in patients with CRSwNP with one or more prior nasal polyp surgeries	4
Pocket guide: biologics in upper and lower airways in adults	4
Therapeutic outcomes of biologic switching in chronic rhinosinusitis with nasal polyps: a systematic review and meta-analysis	4
Real-world-effectiveness of biological treatment for severe chronic rhinosinusitis with nasal polyps	4
Normative data for the lateralization task in the assessment of intranasal trigeminal function	4
Validation of a three-dimensionally printed simulator for training in endoscopic sinonasal surgery	4
Neuromodulators do not appear effective for post-viral parosmia	4
Orthonasal and retronasal olfactory function in olfactory cleft obstructions	4
IL-17A disrupts the nasal mucosal epithelial barrier in patients with chronic rhinosinusitis by activating the ERK/STAT3 pathway	4
Clinical characteristics and management of orbital apex syndrome: a 10-year multicentre experience	4
Low levels of miR-143-3p are associated with severe chronic rhinosinusitis with nasal polyps	4
De-escalation of dupilumab for chronic rhinosinusitis with nasal polyps: analysis of outcomes after modified dosing regimen	4
Small extracellular vesicles facilitate epithelial-mesenchymal transition in chronic rhinosinusitis with nasal polyps via the miR-375-3p/QKI axis	4
Integrating pretreatment 18F-FDG PET-CT parameters, peripheral blood indicators and clinical characteristics in predicting chemotherapy plus immunotherapy outcomes for de novo metastatic nasopharyngea	4
Association between chronic obstructive pulmonary disease and chronic rhinosinusitis: a longitudinal follow-up study using a national health insurance database	4
Olfactory dysfunction in adult cystic fibrosis patients	4
Targeting highly expressed olfactory receptors to improve olfactory testing and training	4
Eosinophils are the dominant type2 marker for the current indication of biological treatment in severe uncontrolled chronic rhinosinusitis with nasal polyps	3
Clinical outcomes of functional endoscopic sinus surgery in cystic fibrosis patients - a single centre experience	3
Olfactory implants: international opinion paper on emerging technologies and clinical applications	3
Responders to biologics in severe uncontrolled chronic rhinosinusitis with nasal polyps: a multicentric observational real-life study	3
Real world efficacy of dupilumab in switchers versus biological naive CRSwNP patients	3
Assessing parosmia patients: a study on the evaluation method using a self-administered odor questionnaire for parosmia	3
Comparison of outcomes for Draf IIB vs Draf III in endoscopic frontal sinus surgery: a comprehensive systematic review and meta-analysis	3
The elongated ciliated cells derived from nasal polyps are distinctly different from ciliated cells in different parts of the nasal mucosa	3
Treatment escalation and sustained disease control in chronic rhinosinusitis: a retrospective surgical cohort study	3
Peak nasal inspiratory flow in chronic obstructive pulmonary disease	3
Mepolizumab in CRSwNP/ECRS and NP: the phase III randomised MERIT trial in Japan, China, and Russia	3

Clinical characteristics and associated factors of qualitative olfactory dysfunction	3
TRIM27 expression is associated with poor prognosis in sinonasal mucosal melanoma	3
Recurrence rates of de-novo versus inverted papilloma-transformed sinonasal squamous cell carcinoma: a meta-analysis	3
Prelacrimal window approach to the maxillary sinus: a systematic review and meta-analysis of the literature	3
Rhinological procedures result in minimal generation of aerosols	3
Combining EBV DNA dynamics with RECIST-based radiographic response to improve prognostic stratification of recurrent/metastatic nasopharyngeal carcinoma in the era of immunotherapy	3
Integration of transcriptomic data identifies CD163 as a key link between chronic rhinosinusitis with nasal polyps and COVID-19	3
Safety and feasibility of the endoscopic endonasal approach to anterior skull base tumour resections in young children	3
The role of TAS2R38 genotype in surgical outcomes and culturable bacteria in chronic rhinosinusitis with or without nasal polyps	3
Overall symptom severity as a patient-reported outcome measure for chronic rhinosinusitis: what it reflects and how to measure it	3
Hydration alters viscosity of nasal secretions in postnasal drip	3
Treating objective outcome measures of chronic rhinosinusitis: are we making the patient or ourselves feel better?	3
Validity and reliability of the Empty Nose Syndrome Index (ENSI)	3
Eosinophilic complications during dupilumab therapy for type 2 diseases: a systematic review	3
From postoperative cerebrospinal fluid leak to meningitis: unveiling the risk factors for meningitis after endoscopic skull base surgery	3